PDB code Error? No. sub No. sub (corrected) Symmetry Symmetry(corrected) PubMed id PubMed id (correction) Annotation comment 101m NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 102l NO 1 1 NPS NPS 8429913 8429913 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 102m NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 103l NO 1 1 NPS NPS 8429913 8429913 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 103m NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 104l_1 PROBNOT 1 1 NPS NPS 8429913 8503008 BU changed since last release and is now corrected - Phage T4 Lysosyme is monomeric - automaticaly inferred from 137l 104l_2 PROBNOT 1 1 NPS NPS 8429913 8503008 BU changed since last release and is now corrected - Phage T4 Lysosyme is monomeric - automaticaly inferred from 137l 104m NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 105m NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 106m NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 107l NO 1 1 NPS NPS 8503008 8503008 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 107m NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 108l NO 1 1 NPS NPS 8503008 8503008 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 108m NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 109l NO 1 1 NPS NPS 8503008 8503008 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 109m NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 10gs NO 2 2 C2 C2 9398518 9398518 -- Annotation transfered from 9gss 110l NO 1 1 NPS NPS 8503008 8503008 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 110m NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 111l NO 1 1 NPS NPS 8503008 8503008 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 111m NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 112l NO 1 1 NPS NPS 8503008 8503008 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 112m NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 113l NO 1 1 NPS NPS 8503008 8503008 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 114l NO 1 1 NPS NPS 8503008 8503008 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 115l NO 1 1 NPS NPS 8503008 8503008 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 117e PROBNOT 2 2 C2 C2 9878371 9878371 SP says dimer -- Annotation transfered from 1wgi 118l NO 1 1 NPS NPS 8218201 8218201 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 119l NO 1 1 NPS NPS 8218201 8218201 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 11ba NO 2 2 C2 C2 10082366 10082366 11bg NO 2 2 C2 C2 10543951 10543951 -- Annotation transfered from 11ba 11gs NO 2 2 C2 C2 9426214 9426214 -- Annotation transfered from 9gss 120l NO 1 1 NPS NPS 8218201 8218201 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 121p PROBYES 2 1 C2 NPS -1 0 Ras proteins are monomeric G proteins (not dimeric) 122l NO 1 1 NPS NPS 8218201 8218201 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 123l NO 1 1 NPS NPS 8218201 8218201 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 125l NO 1 1 NPS NPS 8218201 8218201 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 126l NO 1 1 NPS NPS 8218201 8218201 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 127l NO 1 1 NPS NPS 8218201 8218201 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 128l NO 1 1 NPS NPS 8218201 8218201 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 129l NO 1 1 NPS NPS 8298466 8298466 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 12ca PROBNOT 1 1 NPS NPS 1910042 1910042 9000633 says monomeric -- Annotation transfered from 1uga 12gs NO 2 2 C2 C2 10452896 10452896 -- Annotation transfered from 9gss 130l NO 1 1 NPS NPS 8298466 8298466 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 131l NO 1 1 NPS NPS 8298466 8298466 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 132l NO 1 1 NPS NPS 8373783 8373783 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 133l NO 1 1 NPS NPS 8105095 8105095 Lysozyme C is monomeric -- Annotation transfered from 1lzr 134l NO 1 1 NPS NPS 8105095 8105095 Lysozyme C is monomeric -- Annotation transfered from 1lzr 135l NO 1 1 NPS NPS 15299509 15299509 137l YES 2 1 NS NPS 8503008 8503008 Phage T4 Lysosyme is monomeric 138l NO 1 1 NPS NPS 8177878 8177878 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 139l NO 1 1 NPS NPS 8177878 8177878 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 13gs NO 2 2 C2 C2 10452896 10452896 -- Annotation transfered from 9gss 140l NO 1 1 NPS NPS 8259514 8259514 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 141l NO 1 1 NPS NPS 8259514 8259514 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 142l NO 1 1 NPS NPS 8259514 8259514 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 143l NO 1 1 NPS NPS 8259514 8259514 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 144l NO 1 1 NPS NPS 8259514 8259514 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 145l NO 1 1 NPS NPS 8259514 8259514 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 146l NO 1 1 NPS NPS 8259514 8259514 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 147l NO 1 1 NPS NPS 8259514 8259514 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 148l NO 1 1 NPS NPS 8266098 8266098 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 149l NO 1 1 NPS NPS 7920248 7920248 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 14gs NO 2 2 C2 C2 9665696 9665696 -- Annotation transfered from 9gss 150l_1 NO 1 1 NPS NPS 7920248 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 150l_2 NO 1 1 NPS NPS 7920248 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 150l_3 NO 1 1 NPS NPS 7920248 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 150l_4 NO 1 1 NPS NPS 7920248 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 151l NO 1 1 NPS NPS 7920248 7920248 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 152l NO 1 1 NPS NPS 7920248 7920248 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 155l NO 1 1 NPS NPS 7869383 2916125 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 156l NO 1 1 NPS NPS 7869383 2916125 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 157l NO 1 1 NPS NPS 7869383 2916125 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 158l NO 1 1 NPS NPS 7869383 2916125 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 159l NO 1 1 NPS NPS 7869383 2916125 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 160l NO 1 1 NPS NPS 7869383 2916125 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 161l NO 1 1 NPS NPS 7869383 2916125 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 162l NO 1 1 NPS NPS 7869383 2916125 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 163l NO 1 1 NPS NPS 7869383 2916125 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 164l NO 1 1 NPS NPS 7869383 2916125 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 165l NO 1 1 NPS NPS 7869383 2916125 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 166l NO 1 1 NPS NPS 7869383 2916125 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 167l_1 NO 1 1 NPS NPS 7616572 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 167l_2 NO 1 1 NPS NPS 7616572 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 16gs NO 2 2 C2 C2 9665696 9665696 -- Annotation transfered from 9gss 170l NO 1 1 NPS NPS 7616572 7616572 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 171l NO 1 1 NPS NPS 7616572 7616572 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 172l NO 1 1 NPS NPS 7616572 7616572 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 173l NO 1 1 NPS NPS 7616572 7616572 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 175l_1 NO 1 1 NPS NPS 7616572 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 175l_2 NO 1 1 NPS NPS 7616572 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 177l NO 1 1 NPS NPS 7616572 7616572 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 178l NO 1 1 NPS NPS 7616572 7616572 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 179l NO 1 1 NPS NPS 7616572 7616572 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 17gs NO 2 2 C2 C2 9398518 9398518 -- Annotation transfered from 9gss 180l PROBYES 2 1 NS NPS 7616572 3681997 BU changed since last release and is now incorrect - Phage T4 lysosyme is monomeric - automaticaly inferred from 1l10 181l NO 1 1 NPS NPS 7612599 7612599 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 182l NO 1 1 NPS NPS 7612599 7612599 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 183l NO 1 1 NPS NPS 7612599 7612599 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 184l NO 1 1 NPS NPS 7612599 7612599 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 185l NO 1 1 NPS NPS 7612599 7612599 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 186l NO 1 1 NPS NPS 7612599 7612599 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 187l NO 1 1 NPS NPS 7612599 7612599 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 188l NO 1 1 NPS NPS 7612599 7612599 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 189l NO 1 1 NPS NPS 8771182 8771182 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 18gs NO 2 2 C2 C2 10452896 9665696 -- Annotation transfered from 9gss 190l NO 1 1 NPS NPS 12487988 0 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 191l NO 1 1 NPS NPS 12487988 0 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 192l NO 1 1 NPS NPS 12487988 0 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 193l NO 1 1 NPS NPS 15299672 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 194l NO 1 1 NPS NPS 15299672 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 195l NO 1 1 NPS NPS 8676387 8676387 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 196l NO 1 1 NPS NPS 8676387 8676387 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 197l NO 1 1 NPS NPS 8676387 8676387 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 198l NO 1 1 NPS NPS 8676387 8676387 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 199l NO 1 1 NPS NPS 8676387 8676387 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 19gs NO 2 2 C2 C2 10452896 0 -- Annotation transfered from 9gss 19hc NO 2 2 C2 C2 10368280 10368280 Interface geometry conserved with 1duw (79% id) 1a06 NO 1 1 NPS NPS 8601311 8601311 Paper says CaMKI is a monomeric enzyme 1a07 PROBYES 2 1 NS NPS 9174343 6254988 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution 1a08_1 PROBNOT 1 1 NPS NPS 9174343 6254988 BU changed since last release and is now corrected - In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution - automaticaly inferred from 1a07 1a08_2 PROBNOT 1 1 NPS NPS 9174343 6254988 BU changed since last release and is now corrected - In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution - automaticaly inferred from 1a07 1a09 PROBYES 2 1 NS NPS 9174343 9174343 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1a07 1a0f NO 2 2 C2 C2 9680481 9680481 Interface geometry conserved with 1e6b (23%) -- Annotation transfered from 1n2a 1a0g NO 2 2 C2 C2 9749913 9749913 Homodimer -- Annotation transfered from 2daa 1a0j PROBYES 4 1 NS NPS 9757092 9757092 1a0k PROBNOT 1 1 NPS NPS 9016723 9016723 SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio 1a0l NO 4 4 D2 D2 9521329 9521329 The paper shows tha tit is a tetramer. In addition, it is would be active only as a tetramer 1a15 PROBYES 2 1 C2 NPS 9618518 9618518 Chemokines are known to be predominantly in the monomeric form at physiological concentrations, and monomeric analogs are biologically active. Moreover, sedimentation equilibrium and NMR studies of SDF-1 have indicated that this chemokine is a monomer even at high concentrations. 1a16 NO 4 4 D2 D2 9520390 9520390 BU changed since last release and is now corrected - Paper says tetramer 1a18 PROBYES 2 1 C2 NPS 9680187 9680187 ALBP is monomeric at low and high salt concentrations. -- Annotation transfered from 1ab0 1a1a PROBYES 2 1 NS NPS 9174343 9174343 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1a07 1a1b PROBYES 2 1 NS NPS 9174343 9174343 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1a07 1a1c PROBYES 2 1 NS NPS 9174343 9174343 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1a07 1a1e PROBYES 2 1 NS NPS 9174343 9174343 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1a07 1a1s NO 12 12 Tetr Tetr 9501170 9501170 Interface geometry conserved with 1ort (39%) -- Annotation transfered from 1pvv 1a1v NO 1 1 NPS NPS 9493270 9614113 Although Rep DNA helicase, for example, is a stable monomer in solution in the absence of DNA, a dimeric form of Rep is induced in the presence of DNA which is known as the functional form. So the monomer is still relevant. 1a1x YES 2 1 C2 NPS 9520380 9520380 11679718 says: Solution studies have shown that hTcl1 and mTcl1 form dimers, whereas hMtcp1 exists primarily as a monomer. - Monomer is this one. 1a25 PROBYES 2 1 C2 NPS 9817842 9817842 1a27 NO 2 2 C2 C2 -1 0 Paper says dimer -- Annotation transfered from 3dhe 1a28_1 PROBYES 1 2 NPS C2 9620806 15189034 BU changed since last release and is now incorrect - no info in paper, PISA says dimer - automaticaly inferred from 1sr7 1a28_2 PROBYES 1 2 NPS C2 9620806 15189034 BU changed since last release and is now incorrect - no info in paper, PISA says dimer - automaticaly inferred from 1sr7 1a29 PROBNOT 1 1 NPS NPS 9799490 7634090 -- Annotation transfered from 3cln 1a2b PROBNOT 1 1 NPS NPS 9545299 9545299 1a2d PROBYES 2 1 C2 NPS 9680187 9680187 ALBP is monomeric at low and high salt concentrations. -- Annotation transfered from 1ab0 1a2f PROBNOT 1 1 NPS NPS 0 0 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1a2g PROBNOT 1 1 NPS NPS 0 0 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1a2j NO 1 1 NPS NPS 9655827 10700276 It seems that it is accepted that the native form of the protein is a monomer. 1a2k_2 PROBYES 1 2 NPS C2 9533885 9878368 BU changed since last release and is now incorrect - Paper says dimer - automaticaly inferred from 1byu 1a2l_1 NA 1 1 NPS NPS 9655827 10700276 BU changed since last release and is now corrected - It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant - automaticaly inferred from 1ac1 1a2l_2 NA 1 1 NPS NPS 9655827 10700276 BU changed since last release and is now corrected - It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant - automaticaly inferred from 1ac1 1a2m_1 NA 1 1 NPS NPS 9655827 10700276 BU changed since last release and is now corrected - It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant - automaticaly inferred from 1ac1 1a2m_2 NA 1 1 NPS NPS 9655827 10700276 BU changed since last release and is now corrected - It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant - automaticaly inferred from 1ac1 1a2n PROBYES 3 1 C3 NPS 9485407 9485407 MurA activity was shown to reside on a single monomeric polypeptide chain corresponding to the molecular mass predicted from the gene sequence. -- Annotation transfered from 1uae 1a2p_1 YES 1 3 NPS C3 7078632 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1a2p_2 YES 1 3 NPS C3 7078632 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1a2p_3 YES 1 3 NPS C3 7078632 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1a2q NO 1 1 NPS NPS 2684274 2684274 -- Annotation transfered from 1yja 1a2t NO 1 1 NPS NPS 8762134 8762134 Paper says monomeric -- Annotation transfered from 1ena 1a2u NO 1 1 NPS NPS 8762134 8762134 Paper says monomeric -- Annotation transfered from 1ena 1a2v PROBYES 6 2 D3 C2 15299901 15299901 Paper says dimer 1a2w NO 2 2 C2 C2 9520384 9520384 Yet a third form of the RNAse domain swapped dimer 1a2z NO 4 4 D2 D2 10368293 10368293 Interface geometry conserved with 1iof (50%) 1a30 NO 2 2 C2 C2 9485357 9485357 -- Annotation transfered from 1ajx 1a33 PROBNOT 1 1 NPS NPS 9655334 9655334 Paper says nothing - fragment - PISA says monomer 1a37 NO 2 2 C2 C2 9632691 7603574 14-3-3c forms the canonical dimer found in mammalian 14-3-3 proteins -- Annotation transfered from 1qjb 1a38 NO 2 2 C2 C2 9632691 7603574 14-3-3c forms the canonical dimer found in mammalian 14-3-3 proteins -- Annotation transfered from 1qjb 1a39 PROBNOT 1 1 NPS NPS 9335168 9335168 SP says monomer 1a3c NO 2 2 C2 C2 9551555 9551555 The PyrR dimer differs from other PRTase dimers, suggesting it may have evolved specifically for RNA binding. A large, basic, surface at the dimer interface is an obvious RNA-binding site and uracil specificity is probably provided by hydrogen bonds from mainchain and sidechain atoms in the hood subdomain. 1a3d NO 3 3 C3 C3 9636712 9636712 Forms trimers in many different cryst. conditions so the authors think it is biol. relevant. - The active site is hidden in the trimeric form. The paper discusses the relevance and says it is not understood why the form 94% id does not adopt a trimeric form. - Still an equilibrium exists and enzyme is monomeric when [.] < 0.05 mg/L --> could be activated when released! - interesting 1a3f NO 3 3 C3 C3 9636712 9636712 Forms trimers in many different cryst. conditions so the authors think it is biol. relevant. - The active site is hidden in the trimeric form. The paper discusses the relevance and says it is not understood why the form 94% id does not adopt a trimeric form. - Still an equilibrium exists and enzyme is monomeric when [.] < 0.05 mg/L --> could be activated when released! - interesting -- Annotation transfered from 1a3d 1a3g NO 6 6 D3 D3 9163511 9163511 Paper says hexamer - SP too -- Annotation transfered from 1iyd 1a3k NO 1 1 NPS NPS 9582341 9582341 Paper says monomer 1a3s PROBNOT 1 1 NPS NPS 9757105 9261152 Paper says: Like Arabidopsis thaliana Ubc1 and S. cerevisiae Ubc4, murine/human Ubc9 was crystallized as a monomer 1a3t NO 1 1 NPS NPS 9260275 9260275 Paper says monomeric -- Annotation transfered from 1ena 1a3u NO 1 1 NPS NPS 9260275 9260275 Paper says monomeric -- Annotation transfered from 1ena 1a3v NO 1 1 NPS NPS 9260275 9260275 Paper says monomeric -- Annotation transfered from 1ena 1a3w NO 4 4 D2 D2 9519410 9519410 Interface geometry conserved with 1pkm (50%) 1a3x NO 4 4 D2 D2 9519410 9519410 BU changed since last release and is now corrected - Interface geometry conserved with 1pkm (50%) 1a3y PROBYES 2 1 NS NPS 9609684 9609684 Porcine OBP was believed for a long time to be a monomer under physiological conditions but there are recent data that support the existence of a monomer-dimer equilibrium. - If a dimer that is probably not one with an open symmetry. -- Annotation transfered from 1e02 1a3z PROBNOT 1 1 NPS NPS -1 0 SP says monomer -- Annotation transfered from 1rcy 1a42 PROBNOT 1 1 NPS NPS 9541386 9541386 9000633 says monomeric -- Annotation transfered from 1uga 1a44 PROBNOT 1 1 NPS NPS 9782057 9782057 Nothing said in the paper - PISA says monomer. An email was sent to the authors 1a45 NA 2 2 C2 C2 9367641 9367641 Under these conditions the bovine γF protein molecules in the very dense protein phase may tend to attract each other into arrays as indicated in Fig. 4(B) and 4(C). This is a hypothetical interaction but it makes sense. So depending on the [.] there is possibly a monomer dimer oligomer equilibrium - still note that PID 3052280 says that gamma crystallins are monomeric 1a47 PROBNOT 1 1 NPS NPS 9488711 9488711 Paper says nothing but Cyclodextrin-glycosyltransferase are monomeric - PISA also says so. 1a49_1 PROBNOT 4 4 D2 D2 9572839 8193145 BU changed since last release and is now corrected - 15299671 says tetramer - automaticaly inferred from 1pkn 1a49_2 PROBNOT 4 4 D2 D2 9572839 8193145 BU changed since last release and is now corrected - 15299671 says tetramer - automaticaly inferred from 1pkn 1a4b NA 2 1 C2 NPS 9520385 9520385 No clear info found -- Annotation transfered from 1azc 1a4e NO 4 4 D2 D2 9931255 9931255 Interface geometry conserved with 1mqf (45% id) 1a4h NO 2 2 C2 C2 9230303 9230303 1a4o_1 NO 2 2 C2 C2 7603574 10488331 14-3-3c forms the canonical dimer found in mammalian 14-3-3 proteins - automatic transfer from 1qjb 1a4o_2 NO 2 2 C2 C2 7603574 10488331 14-3-3c forms the canonical dimer found in mammalian 14-3-3 proteins - automatic transfer from 1qjb 1a4p YES 2 4 C2 C2 9886297 9886297 Wrong interface chosen - tetramer because of a disulfide bridge 1a4r PROBYES 2 1 C2 NPS 10211824 10211824 1a4s NO 4 4 D2 D2 9792097 9792097 Paper says tetramer 1a4u NO 2 2 C2 C2 9735295 9735295 Paper says dimer 1a4v PROBNOT 1 1 NPS NPS 9537992 9537992 SP says: Lactose synthase (LS) is a heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA). -- Annotation transfered from 1b9o 1a4x PROBNOT 2 2 C2 C2 9551555 9551555 Paper says: The aggregation state of PyrR is variable. The apparent molecular weight for the major species eluted in gel filtration experiments is directly proportional to protein concentration [5]. On the basis of the crystal structures, rapid equilibrium between dimeric and hexameric species is inferred. The small buried surface area and lack of hydrogen bonds in the threefold interface of the hexamer imply that it is not a biologically relevant subunit interaction [46]. The hexameric form of PyrR therefore may be non-physiological and due only to the relatively high in vitro concentrations used during both gel filtration and crystallographic studies. -- dimer hexamer equilibrium 1a4z NO 4 4 D2 D2 9195888 9195888 Interface geometry conserved with 1uxr (30%) 1a50 NO 4 4 C2 C2 9548921 9548921 Paper says a2b2 -- Annotation transfered from 2wsy 1a52 NO 2 2 C2 C2 9600906 9600906 paper says dimer -- Annotation transfered from 1err 1a58 PROBNOT 1 1 NPS NPS 9559680 9559680 Paper says nothing - fragment - PISA says monomer -- Annotation transfered from 1a33 1a59 NO 2 2 C2 C2 9551556 9551556 Interface geometry conserved with 6cts (27%) 1a5a NO 4 4 C2 C2 9535826 9535826 Paper says a2b2 -- Annotation transfered from 2wsy 1a5b NO 4 4 C2 C2 9535826 9535826 Paper says a2b2 -- Annotation transfered from 2wsy 1a5i PROBNOT 1 1 NPS NPS 9354616 9354616 SP says monomer 1a5k NO 9 9 C3 C3 9558361 9558361 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1a5l NO 9 9 C3 C3 9558361 9558361 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1a5m NO 9 9 C3 C3 9558361 9558361 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1a5n NO 9 9 C3 C3 9558361 9558361 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1a5o NO 9 9 C3 C3 9558361 9558361 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1a5p NO 1 1 NPS NPS 9605332 9605332 -- Annotation transfered from 6rsa 1a5q NO 1 1 NPS NPS 9605332 9605332 -- Annotation transfered from 6rsa 1a5s NO 4 4 C2 C2 9548921 9548921 Paper says a2b2 -- Annotation transfered from 2wsy 1a5u_1 PROBNOT 4 4 D2 D2 9572839 8193145 BU changed since last release and is now corrected - 15299671 says tetramer - automaticaly inferred from 1pkn 1a5u_2 PROBNOT 4 4 D2 D2 9572839 8193145 BU changed since last release and is now corrected - 15299671 says tetramer - automaticaly inferred from 1pkn 1a5v NO 2 2 C2 C2 9560188 9560188 Interface is conserved with 1itg even though seq sim is ~35% so I believe this interface is functionally relevant (plus it is known to oligomerize). - very interesting -- Annotation transfered from 1cxu 1a5w PROBYES 2 2 C2 C2 9560188 9560188 This dimer might be right but another form (with another interface), the one found in 1a5v (same sequence as this one), is similar to 1itg even though there is little seq similarity (30%). So Id say that the conserved interface is probably right. This one could be as well since SP say it is a homotetramer, but I believe more in the conserved one so for now I ll say this one is wrong. (PISA might be wrong too then). 1a5x PROBYES 2 2 C2 C2 9560188 9560188 This dimer might be right but another form (with another interface), the one found in 1a5v (same sequence as this one), is similar to 1itg even though there is little seq similarity (30%). So Id say that the conserved interface is probably right. This one could be as well since SP say it is a homotetramer, but I believe more in the conserved one so for now I ll say this one is wrong. (PISA might be wrong too then). 1a5y PROBNOT 1 1 NPS NPS 9553104 9553104 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1a5z NO 4 4 D2 D2 9655830 9655830 Paper says tetramer 1a64 NO 2 2 C2 C2 9731771 9731771 The same sequence is found to form a tetrameric assembly under high ionic strenght. 1a65 PROBNOT 1 1 NPS NPS 9546223 9546223 Paper says: C. cinereus laccase is a monomeric molecule consisting of three tightly associated cupredoxin-like domains -- Annotation transfered from 1hfu 1a68 NO 4 4 C4 C4 9582078 9582078 Interface geometry conserved with 3kvt (42%) -- Annotation transfered from 1t1d 1a69 NO 6 6 D3 D3 9653038 9653038 Paper and SP say hexamer -- Annotation transfered from 1ovg 1a6d NO 16 16 D8 D8 9546398 9546398 1a6e NO 16 16 D8 D8 9546398 9546398 1a6g NO 1 1 NPS NPS 10512835 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1a6k NO 1 1 NPS NPS 10512835 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1a6l NO 1 1 NPS NPS 9837955 9837955 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1a6m NO 1 1 NPS NPS 10512835 0 Myoglobin is a monomeric protein (8663546) 1a6n NO 1 1 NPS NPS 10512835 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1a6r NO 6 6 D3 D3 9546396 9546396 SP says hexamer and interface geometry conserved with 1cb5 (38%) -- Annotation transfered from 3gcb 1a6y NO 2 2 NS NS 9660968 9660968 Binds direct DNA repeats -- Annotation transfered from 1hlz 1a71 NO 2 2 C2 C2 9649310 9649310 -- Annotation transfered from 8adh 1a72 NO 2 2 C2 C2 9649310 9649310 -- Annotation transfered from 8adh 1a76 PROBNOT 1 1 NPS NPS 9699635 9699635 Paper doesn mention oligomer, FEN-1 seems monomeric in other species and PISA says monomer. -- Annotation transfered from 1a77 1a77 PROBNOT 1 1 NPS NPS 9699635 9699635 Paper doesn mention oligomer, FEN-1 seems monomeric in other species and PISA says monomer. 1a78 NO 2 2 C2 C2 10861929 10861929 Paper says dimer 1a7a NO 4 4 D2 D2 9586999 9586999 SP says tetramer, interface geometry conserved among rat and human. -- Annotation transfered from 1b3r 1a7b NO 4 4 D2 D2 9731771 9731771 The same sequence is found to form a dimeric assembly under low ionic strenght. 1a7c PROBNOT 1 1 NPS NPS 9634700 9634700 Paper says nothing - Family mostly monomeric - PISA says monomer -- Annotation transfered from 1dvn 1a7d NO 1 1 NPS NPS 9188702 9188702 PAper says monomer: Monomeric analogues of hemerythrin and hemoglobin, found in muscle tissue, have been designated myohemerythrin and myoglobin 1a7e NO 1 1 NPS NPS 9188702 9188702 PAper says monomer: Monomeric analogues of hemerythrin and hemoglobin, found in muscle tissue, have been designated myohemerythrin and myoglobin -- Annotation transfered from 1a7d 1a7k NO 4 4 D2 D2 9571030 9571030 SP says tetramer - papers too 1a7l_1 PROBNOT 1 1 NPS NPS 9654443 12794084 EcoCyc says monomer - automatic transfer from 1nl5 1a7l_2 PROBNOT 1 1 NPS NPS 9654443 12794084 EcoCyc says monomer - automatic transfer from 1nl5 1a7l_3 PROBNOT 1 1 NPS NPS 9654443 12794084 EcoCyc says monomer - automatic transfer from 1nl5 1a7s NO 1 1 NPS NPS 9761855 9761855 PISA and SP say monomer 1a7t YES 2 1 NS NPS 9578564 9730812 1a7u YES 2 3 NS C3 9642069 9642069 -- Interface geometry conserved with 1a88 1a7x YES 2 1 C2 NPS 9871618 9871618 Normally monomeric in solution - But very interesting: one mutation (F36M) transforms it into an inducible dimer. Isnt that so interesting? It thus also shows that it can be very simple to form a heterointerfaces, and that a high proportion of supposedly errors in the BU can reflect a potential high affinity (given that 1/2 mutations are introduced) - very nice example! -- Annotation transfered from 2fke 1a80 NA 1 1 NPS NPS 9618487 9618487 SwissProt says monomer but PISA says dimer. The contacts established in the dimeric form are also found in 1ef3 which is a bit puzzling. --> investigate more - interesting case. -- Annotation transfered from 1m9h 1a82 NO 2 2 C2 C2 9576910 9576910 Active form is a homodimer 1a85 PROBNOT 1 1 NPS NPS 9655333 9655333 No clear evidence after a quick search but PISA agrees ... 1a86 PROBNOT 1 1 NPS NPS 9655333 9655333 No clear evidence after a quick search but PISA agrees ... -- Annotation transfered from 1a85 1a88 NO 3 3 C3 C3 9642069 9642069 Interface conserved with 1brt (40% id) 1a8a PROBNOT 1 1 NPS NPS 7583670 7583670 SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1n42 1a8b PROBNOT 1 1 NPS NPS 7583670 7583670 SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1n42 1a8g NO 2 2 C2 C2 10047488 10047488 -- Annotation transfered from 1ajx 1a8i NO 2 2 C2 C2 9568898 9568898 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1a8j NO 2 2 C2 C2 9630831 9630831 1a8k_1 PROBNOT 2 2 C2 C2 9370363 10651036 BU changed since last release and is now corrected - - automaticaly inferred from 3tlh 1a8k_2 PROBNOT 2 2 C2 C2 9370363 10651036 BU changed since last release and is now corrected - - automaticaly inferred from 3tlh 1a8m NO 3 3 C3 C3 9488135 9488135 SP and paper say trimer -- Annotation transfered from 4tsv 1a8q PROBYES 1 3 NPS C3 9642069 9642069 Interface conserved with 1a88 (50%) 1a8s YES 1 3 NPS C3 9642069 9642069 -- Interface conserved with 1a88 (60%) 1a8t_1 PROBNOT 1 1 NPS NPS 9545432 9730812 BU changed since last release and is now corrected - - automaticaly inferred from 1a7t 1a8t_2 PROBNOT 1 1 NPS NPS 9545432 9730812 BU changed since last release and is now corrected - - automaticaly inferred from 1a7t 1a8u YES 2 3 NS C3 9642069 9642069 -- Interface geometry conserved with 1a88 -- Annotation transfered from 1a7u 1a95 NO 4 4 D2 D2 9743633 9743633 XGPRT exists as a tetramer both in solution (as determined by gel-filtration studies; [Vos et al 1997]) and in the crystals. The subunit arrangement observed for XGPRT may explain why tetramers are required for enzyme function, since three of the four subunits may be contributing residues to each of the four active sites in the tetramer. More details in the paper -- Annotation transfered from 1a97 1a96 NO 4 4 D2 D2 9743633 9743633 XGPRT exists as a tetramer both in solution (as determined by gel-filtration studies; [Vos et al 1997]) and in the crystals. The subunit arrangement observed for XGPRT may explain why tetramers are required for enzyme function, since three of the four subunits may be contributing residues to each of the four active sites in the tetramer. More details in the paper -- Annotation transfered from 1a97 1a97 NO 4 4 D2 D2 9743633 9743633 XGPRT exists as a tetramer both in solution (as determined by gel-filtration studies; [Vos et al 1997]) and in the crystals. The subunit arrangement observed for XGPRT may explain why tetramers are required for enzyme function, since three of the four subunits may be contributing residues to each of the four active sites in the tetramer. More details in the paper - !?Swissprot wrong: says trimer?! 1a98 NO 4 4 D2 D2 9743633 0 XGPRT exists as a tetramer both in solution (as determined by gel-filtration studies; [Vos et al 1997]) and in the crystals. The subunit arrangement observed for XGPRT may explain why tetramers are required for enzyme function, since three of the four subunits may be contributing residues to each of the four active sites in the tetramer. More details in the paper -- Annotation transfered from 1a97 1a9m NO 2 2 C2 C2 9450540 9450540 -- Annotation transfered from 1ajx 1a9o NO 3 3 C3 C3 9585525 9585525 Paper says trimer -- Annotation transfered from 1v48 1a9p NO 3 3 C3 C3 9585525 9585525 Paper says trimer -- Annotation transfered from 1v48 1a9q NO 3 3 C3 C3 9585525 9585525 Paper says trimer -- Annotation transfered from 1v48 1a9r NO 3 3 C3 C3 9585525 9585525 Paper says trimer -- Annotation transfered from 1v48 1a9s NO 3 3 C3 C3 9585525 9585525 Paper says trimer -- Annotation transfered from 1v48 1a9t NO 3 3 C3 C3 9585525 9585525 Paper says trimer -- Annotation transfered from 1v48 1a9u PROBNOT 1 1 NPS NPS 9753691 9753691 -- Annotation transfered from 1kv1 1a9x PROBNOT 8 8 D2 D2 9636022 11551199 Carbamoyl phosphate synthetase (CPS) from Escherichia coli is allosterically regulated by the metabolites ornithine, IMP, and UMP. Ornithine and IMP function as activators, whereas UMP is an inhibitor. CPS undergoes changes in the state of oligomerization that are dependent on the protein concentration and the binding of allosteric effectors. Ornithine and IMP promote the formation of an (ab)4 tetramer while UMP favors the formation of an (ab)2 dimer. Propagate to all (CPS) please! -) -- Annotation transfered from 1bxr 1a9y NO 2 2 C2 C2 9708982 9708982 SP says homodimer -- Annotation transfered from 2udp 1a9z NO 2 2 C2 C2 9708982 9708982 SP says homodimer -- Annotation transfered from 2udp 1aa4 PROBNOT 1 1 NPS NPS 8673607 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aac NO 1 1 NPS NPS 15299631 8495197 Amicyanin is a monomeric protein with a molecular weight of 15000 (Husain & Davidson, 1985) -- Annotation transfered from 1aaj 1aaj NO 1 1 NPS NPS 8495197 8495197 Amicyanin is a monomeric protein with a molecular weight of 15000 (Husain & Davidson, 1985) 1aam NO 2 2 C2 C2 7909946 7909946 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1aan NO 1 1 NPS NPS 8495197 8495197 Amicyanin is a monomeric protein with a molecular weight of 15000 (Husain & Davidson, 1985) -- Annotation transfered from 1aaj 1aap NA 2 2 C2 C2 2125487 2125487 Paper not online - Amyloid beta A4 protein (protein normally 770aa, and this fragment is 56 so I am not sure about this dimer) 1aaq NO 2 2 C2 C2 1637805 1637805 -- Annotation transfered from 1ajx 1aar PROBNOT 2 2 C2 C2 1322903 1322903 Ubiquitin binds to proteins in different forms that may lead to the degradation of the target protein. For this reason I will consider all the ubiquitin structures to be correct. i.e. different forms may exist. -- Annotation transfered from 1tbe 1aat NO 2 2 C2 C2 7151682 7151682 BU changed since last release and is now corrected - 1aaw NO 2 2 C2 C2 7909946 7909946 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1aax PROBNOT 1 1 NPS NPS 9391040 9391040 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1ab0 PROBYES 2 1 C2 NPS 9092513 12794068 ALBP is monomeric at low and high salt concentrations. 1ab1 PROBNOT 1 1 NPS NPS 8450543 8450543 Although no clear reference was found, it is accepted to me that crambin is at least predominantly monomeric in somution. 1ab5_1 PROBNOT 1 1 NPS NPS 9761905 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 1ab5_2 PROBNOT 1 1 NPS NPS 9761905 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 1ab6_1 PROBNOT 1 1 NPS NPS 9761905 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 1ab6_2 PROBNOT 1 1 NPS NPS 9761905 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 1abb NO 4 4 D2 D2 1304390 1304390 Paper says: Phosphorylase reconstituted with PLPP is not active, but the modified enzyme exhibits properties the of R-state conformation as detected by high affinity for AMP and aggregation of dimers to tetramers (Withers et al., 1982). 1abe NO 1 1 NPS NPS 6379466 6379466 EcoCyc says monomer 1abf NO 1 1 NPS NPS 2818726 2818726 EcoCyc says monomer -- Annotation transfered from 1abe 1abn NO 1 1 NPS NPS 1447221 1447221 SwissProt and PISA say monomer -- Annotation transfered from 1ads 1abo_1 PROBNOT 1 1 NPS NPS 7664083 7664083 BU changed since last release and is now corrected - PISA says monomer, SH3 domain are functional as monomers - automaticaly inferred from 1abq 1abo_2 PROBNOT 1 1 NPS NPS 7664083 7664083 BU changed since last release and is now corrected - PISA says monomer, SH3 domain are functional as monomers - automaticaly inferred from 1abq 1abq PROBYES 2 1 C2 NPS 7664083 7664083 PISA says monomer, SH3 domain are functional as monomers 1abs NO 1 1 NPS NPS 7935843 7935843 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1ac1 NA 2 1 C2 NPS 9300489 10700276 It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant 1ac4 PROBNOT 1 1 NPS NPS 8673607 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1ac5 PROBNOT 1 1 NPS NPS 8745419 8745419 Paper says nothing, PISA says monomer 1ac6 NO 2 2 C2 C2 9199407 9199407 Classic interface 1ac8 PROBNOT 1 1 NPS NPS 8673607 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1acd PROBYES 2 1 C2 NPS 9092513 9092513 ALBP is monomeric at low and high salt concentrations. -- Annotation transfered from 1ab0 1acf PROBNOT 1 1 NPS NPS 8078936 8078936 SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio -- Annotation transfered from 1prq 1acj PROBNOT 1 1 NPS NPS 8415649 8415649 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. 1acl PROBNOT 1 1 NPS NPS 8415649 8415649 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1acm NO 12 12 D3 D3 1303763 1303763 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1acv NA 2 1 C2 NPS 9300489 10700276 It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant 1acx PROBNOT 1 1 NPS NPS -1 0 No paper but PISA, PQS and PDB agree so I ll assume it is a monomer 1ad3 NO 2 2 C2 C2 9095201 9095201 Paper says dimer -- good interesting example to show the exponential explosion of hits when below 30% !! 1ad5_1 NO 1 1 NPS NPS 9024658 10360180 The author of 2hck told me it was known to be a monomer - automatic transfer from 1qcf 1ad5_2 NO 1 1 NPS NPS 9024658 10360180 The author of 2hck told me it was known to be a monomer - automatic transfer from 1qcf 1adb NO 2 2 C2 C2 7918390 7918390 -- Annotation transfered from 8adh 1adc NO 2 2 C2 C2 7918390 7918390 -- Annotation transfered from 8adh 1adf NO 2 2 C2 C2 8286346 8286346 -- Annotation transfered from 8adh 1adg NO 2 2 C2 C2 8286346 8286346 -- Annotation transfered from 8adh 1adj_1 NO 2 2 C2 C2 9115984 11399074 BU changed since last release and is now corrected - Interface geometry conserved with 1ge0 (42%) - automatic transfer from 1h4v 1adj_2 NO 2 2 C2 C2 9115984 11399074 BU changed since last release and is now corrected - Interface geometry conserved with 1ge0 (42%) - automatic transfer from 1h4v 1adl PROBYES 2 1 C2 NPS 7929228 7929228 ALBP is monomeric at low and high salt concentrations. -- Annotation transfered from 1ab0 1ads NO 1 1 NPS NPS 1621098 1621098 SwissProt and PISA say monomer 1adt PROBYES 1 2 NPS NS 8039495 8632448 BU changed since last release and is now incorrect - Paper says: Dynamic light-scattering shows that the C-terminal domain is inde ed p olymeric in solution. - automaticaly inferred from 1adu 1adu PROBNOT 2 2 NS NS 8632448 8632448 Paper says: Dynamic light-scattering shows that the C-terminal domain is inde ed p olymeric in solution. 1adv PROBNOT 2 2 NS NS 8632448 8632448 Paper says: Dynamic light-scattering shows that the C-terminal domain is inde ed p olymeric in solution. -- Annotation transfered from 1adu 1adw PROBYES 2 1 C2 NPS 7583671 0 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 1ady_1 NO 2 2 C2 C2 9115984 11399074 BU changed since last release and is now corrected - Interface geometry conserved with 1ge0 (42%) - automatic transfer from 1h4v 1ady_2 NO 2 2 C2 C2 9115984 11399074 BU changed since last release and is now corrected - Interface geometry conserved with 1ge0 (42%) - automatic transfer from 1h4v 1ae1 NO 2 2 C2 C2 9560196 9560196 say dimer in paper 1ae4 NO 1 1 NPS NPS 9329083 9329083 Swissprot and PISA say monomer -- Annotation transfered from 1cwn 1ae5 NO 1 1 NPS NPS 9095193 9095193 PISA and SP say monomer -- Annotation transfered from 1a7s 1ae7 PROBNOT 1 1 NPS NPS 1568473 1568473 SP says monomer 1aeb PROBNOT 1 1 NPS NPS 11812152 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aec PROBNOT 1 1 NPS NPS 1606141 1606141 related proteins are monomeric and PISA says monomer -- example for illustrating a case where I am not too sure 1aed PROBNOT 1 1 NPS NPS 11812152 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aee PROBNOT 1 1 NPS NPS 11812152 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aef PROBNOT 1 1 NPS NPS 11812152 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aeg PROBNOT 1 1 NPS NPS 11812152 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aeh PROBNOT 1 1 NPS NPS 11812152 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aei NO 6 6 D3 D3 7477411 7477411 The annexin XII (ANXB12) crystal structure presented evidence that calcium mediates the formation of a hexamer through a novel intermolecular calcium-binding site - calcium induced hexamerization - very interesting! -- Annotation transfered from 1dm5 1aej PROBNOT 1 1 NPS NPS 11812152 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aek PROBNOT 1 1 NPS NPS 11812152 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aem PROBNOT 1 1 NPS NPS 11812152 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aen PROBNOT 1 1 NPS NPS 11812152 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aeo PROBNOT 1 1 NPS NPS 11812152 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aeq PROBNOT 1 1 NPS NPS 11812152 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aes PROBNOT 1 1 NPS NPS 8673607 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aet PROBNOT 1 1 NPS NPS 8673607 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aeu PROBNOT 1 1 NPS NPS 8673607 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aev PROBNOT 1 1 NPS NPS 9305956 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1aew NO 24 24 Octa Octa 9159481 9159481 Interface geometry conserved with 1lb3 (80%) -- Annotation transfered from 1ies 1aex NO 1 1 NPS NPS 8762134 8762134 Paper says monomeric -- Annotation transfered from 1ena 1af4 NO 1 1 NPS NPS 9113975 9113975 -- Annotation transfered from 1be6 1afk_1 PROBNOT 1 1 NPS NPS 9154942 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1afk_2 PROBNOT 1 1 NPS NPS 9154942 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1afl_1 PROBNOT 1 1 NPS NPS 9154942 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1afl_2 PROBNOT 1 1 NPS NPS 9154942 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1afs PROBYES 2 1 C2 NPS 9261071 9261071 Said to be monomeric in the paper. Also nice paragraph about the function of the prot -- Annotation transfered from 1lwi 1afu_1 PROBNOT 1 1 NPS NPS 9154942 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1afu_2 PROBNOT 1 1 NPS NPS 9154942 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1afw NO 2 2 C2 C2 9402066 9402066 Paper says dimer 1ag0_1 PROBNOT 1 1 NPS NPS 0 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1ag0_2 PROBNOT 1 1 NPS NPS 0 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1ag1 PROBNOT 2 2 C2 C2 2040290 2040290 SP says dimer -- Annotation transfered from 6tim 1ag6 PROBNOT 1 1 NPS NPS 9792096 9792096 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) -- Annotation transfered from 1oow 1ag8 NO 4 4 D2 D2 9195888 9195888 Interface geometry conserved with 1uxr (30%) -- Annotation transfered from 1a4z 1ag9 NA 2 1 C2 NPS 9416602 9416602 Most similar flavodoxins are monomers but it was shown that: the dimerized flavodoxin from Azotobacter lacks biological activity (Yoch, 1975), suggesting that the dimerization blocks formation of the transient complexes that are involved in electron transfer. So dimerization might have a role similar to that in the thioredoxin (1fvk). 1agi NO 1 1 NPS NPS 7708754 7708754 1agn_1 PROBNOT 2 2 C2 C2 9228021 10631979 BU changed since last release and is now corrected - - automaticaly inferred from 1d1t 1agn_2 PROBNOT 2 2 C2 C2 9228021 10631979 BU changed since last release and is now corrected - - automaticaly inferred from 1d1t 1agp PROBYES 2 1 C2 NPS 8357792 8357792 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 1ags NO 2 2 C2 C2 7892174 7892174 BU changed since last release and is now corrected - No structure present? 1agw_1 PROBNOT 1 1 NPS NPS 9139660 9774334 BU changed since last release and is now corrected - Paper does not mention dimer and PISA says monomer - automaticaly inferred from 2fgi 1agw_2 PROBNOT 1 1 NPS NPS 9139660 9774334 BU changed since last release and is now corrected - Paper does not mention dimer and PISA says monomer - automaticaly inferred from 2fgi 1ah0 NO 1 1 NPS NPS 9195881 9195881 SwissProt an dPISA say monomer -- Annotation transfered from 1ah3 1ah3 NO 1 1 NPS NPS 9195881 9195881 SwissProt an dPISA say monomer 1ah4 NO 1 1 NPS NPS 9195881 9195881 SwissProt an dPISA say monomer -- Annotation transfered from 1ah3 1ah6 NO 2 2 C2 C2 9187656 9187656 -- Annotation transfered from 1a4h 1ah8 NO 2 2 C2 C2 9187656 9187656 -- Annotation transfered from 1a4h 1aha PROBNOT 1 1 NPS NPS 8075985 8075985 No info in papers, PISA says monomer 1ahb PROBNOT 1 1 NPS NPS 8075985 8075985 No info in papers, PISA says monomer -- Annotation transfered from 1aha 1ahc PROBNOT 1 1 NPS NPS 8075985 8075985 No info in papers, PISA says monomer -- Annotation transfered from 1aha 1ahe NO 2 2 C2 C2 7664122 7664122 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1ahf NO 2 2 C2 C2 7664122 7664122 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1ahg NO 2 2 C2 C2 7664122 7664122 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1ahh NO 4 4 D2 D2 8672472 8672472 said in paper -- Annotation transfered from 1fmc 1ahi NO 4 4 D2 D2 8672472 8672472 said in paper -- Annotation transfered from 1fmc 1ahn NO 1 1 NPS NPS 9416602 9416602 Most similar prots are also monomer. 1ahp NO 2 2 C2 C2 9145112 9145112 -- Annotation transfered from 2ecp 1ahr PROBNOT 1 1 NPS NPS 9195880 9195880 -- Annotation transfered from 3cln 1ahu NO 8 8 D4 D4 9261083 9141139 Paper says octamer -- Annotation transfered from 2vao 1ahv YES 8 2 NS C2 9261083 9141139 Seems this crystal form is not compatible with a hexamer. -- Annotation transfered from 1ahz 1ahx NO 2 2 C2 C2 7664122 7664122 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1ahy NO 2 2 C2 C2 7664122 7664122 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1ahz YES 8 2 NS C2 9261083 9141139 Seems this crystal form is not compatible with a hexamer. 1ai9 PROBYES 2 1 C2 NPS 9374515 9374515 Paper says nothing - PISA says monomer and related proteins are monomeric 1aia NO 2 2 C2 C2 7819232 7819232 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1aib NO 2 2 C2 C2 7819232 7819232 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1aic NO 2 2 C2 C2 7819232 7819232 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1aid NO 2 2 C2 C2 8340363 8340363 -- Annotation transfered from 1ajx 1aii PROBNOT 1 1 NPS NPS 9111038 9111038 PISA says monomer and related proteins are monomeric -- Annotation transfered from 1axn 1aim NO 1 1 NPS NPS 9260273 9260273 The enzyme is a monomeric glycoprotein -- Annotation transfered from 1me4 1aiq NO 2 2 C2 C2 9416600 9416600 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1aiu PROBNOT 2 2 C2 C2 9369469 9369469 SP says dimer, paper too, interface geometry conserved with 1nsw (36%) - monomer dimer equilibrium -- very interesting paper: quantification of the interface strengh according to the pH (> 10 fold difference). 1aiz NA 2 1 C2 NPS 15299522 0 No clear info found -- Annotation transfered from 1azc 1aj0 YES 1 2 NPS C2 9187658 9187658 SP says dimer - interface geometry conseved with 1eye (41%) 1aj2 YES 1 2 NPS C2 9187658 9187658 SP says dimer - interface geometry conseved with 1eye (41%) -- Annotation transfered from 1aj0 1aj5_1 PROBNOT 2 2 C2 C2 9228945 14579356 BU changed since last release and is now corrected - - automaticaly inferred from 1np8 1aj5_2 PROBNOT 2 2 C2 C2 9228945 14579356 BU changed since last release and is now corrected - - automaticaly inferred from 1np8 1aj8 NO 2 2 C2 C2 9254593 9254593 Interface geometry conserved with 1a59 (38%) 1ajg NO 1 1 NPS NPS 7634074 7634074 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1ajh NO 1 1 NPS NPS 7634074 7634074 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1ajm NO 2 2 C2 C2 9416600 9416600 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1ajr NO 2 2 C2 C2 9211866 9211866 Interface geometry conserved with 2ay6 (36%) -- Annotation transfered from 1ajs 1ajs NO 2 2 C2 C2 9211866 9211866 Interface geometry conserved with 2ay6 (36%) 1ajv NO 2 2 C2 C2 9083478 9083478 -- Annotation transfered from 1ajx 1ajx NO 2 2 C2 C2 9083478 9083478 1ajz YES 1 2 NPS C2 9187658 9187658 SP says dimer - interface geometry conseved with 1eye (41%) -- Annotation transfered from 1aj0 1ak2 PROBNOT 1 1 NPS NPS 8868479 8868479 SP says monomer 1ak9 NO 1 1 NPS NPS 2684274 2684274 -- Annotation transfered from 1yja 1aka NO 2 2 C2 C2 7819232 0 Interface geometry conserved with 2ay6 (38%) -- Annotation transfered from 1ivr 1akb NO 2 2 C2 C2 7819232 7819232 Interface geometry conserved with 2ay6 (38%) -- Annotation transfered from 1ivr 1akc NO 2 2 C2 C2 7819232 7819232 Interface geometry conserved with 2ay6 (38%) -- Annotation transfered from 1ivr 1akd PROBNOT 1 1 NPS NPS 9357977 9357977 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1ake_1 PROBNOT 1 1 NPS NPS 1548697 0 BU changed since last release and is now corrected - SP and EcoCyc say monomer - automaticaly inferred from 1e4y 1ake_2 PROBNOT 1 1 NPS NPS 1548697 0 BU changed since last release and is now corrected - SP and EcoCyc say monomer - automaticaly inferred from 1e4y 1aki NO 1 1 NPS NPS -1 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1akm PROBNOT 3 3 C3 C3 9253409 9253409 Paper says trimer: Anabolic OTCase is the simplest form of the enzyme, comprising a single homotrimeric unit -- Annotation transfered from 1duv 1akn NO 1 1 NPS NPS 9331420 9331420 Paper says monomer -- Annotation transfered from 2bce 1akq PROBNOT 1 1 NPS NPS 12206666 9874201 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1f4p 1akr PROBNOT 1 1 NPS NPS 9622492 9622492 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1f4p 1akt PROBNOT 1 1 NPS NPS 9622492 9622492 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1f4p 1aku PROBNOT 1 1 NPS NPS 12206666 0 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1f4p 1akv PROBNOT 1 1 NPS NPS 12206666 0 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1f4p 1akw PROBNOT 1 1 NPS NPS 9622492 9622492 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1f4p 1aky PROBNOT 1 1 NPS NPS 7670369 7670369 SP and PISA say monomer -- Annotation transfered from 2aky 1al6 NO 2 2 C2 C2 0 0 Interface geometry conserved with 1a59 (27%) -- Annotation transfered from 6cts 1ala PROBNOT 1 1 NPS NPS 8471604 8471604 PISA says monomer and related proteins are monomeric 1alb NO 1 1 NPS NPS 1554730 12794068 ALBP is monomeric at low and high salt concentrations. 1alc PROBNOT 1 1 NPS NPS 2769757 2769757 SP says: Lactose synthase (LS) is a heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA). -- Annotation transfered from 1b9o 1alq PROBYES 2 1 C2 NPS 9220963 9220963 Class A betalactamase are apparently monomeric in solution (said in paper) -- Annotation transfered from 1kgf 1alv NO 2 2 C2 C2 9228946 9228946 1alw NO 2 2 C2 C2 9228946 9228946 -- Annotation transfered from 1alv 1aly PROBNOT 3 3 C3 C3 8589998 8589998 SP says trimer 1am1 NO 2 2 C2 C2 9230303 9230303 -- Annotation transfered from 1a4h 1am6 PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1am7 PROBYES 3 1 NS NPS 9514719 9514719 No oligo mentionned 1ama NO 2 2 C2 C2 1522585 1522585 Interface geometry conserved with 2ay6 (38%) -- Annotation transfered from 1ivr 1amh PROBYES 2 1 C2 NPS 7795518 7795518 Trysin is monomeric -- Annotation transfered from 1anb 1amk NO 2 2 C2 C2 10235625 0 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1n55 1amm PROBNOT 1 1 NPS NPS 15299624 0 y-Crystallins are exclusively monomeric -- Annotation transfered from 1gcs 1amp PROBYES 2 1 C2 NPS 8087555 8087555 Aminopeptidase from Aeromonas proteolytica (AAP) is a small, monomeric enzyme (32KDa) -- Annotation transfered from 1igb 1amq NO 2 2 C2 C2 7896726 7896726 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1amr NO 2 2 C2 C2 7896726 7896726 Interface geometry conserved with 2ay6 (45%) 1ams NO 2 2 C2 C2 7896726 7896726 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1amw NO 2 2 C2 C2 9230303 9230303 -- Annotation transfered from 1a4h 1amy NO 1 1 NPS NPS 8196040 9571044 alpha-Amylases (a-1,4 glucan-4-glucanohydrolase, EC 3.2.1.1) are monomeric enzymes that catalyse the hydrolysis of internal a-D-(1,4) glucosidic linkages in starch and related oligo- and polysaccharides with release of malto-oligosaccharides and glucose in the alpha-anomeric form. 1amz NO 2 2 C2 C2 0 0 Interface geometry conserved with 1a59 (27%) -- Annotation transfered from 6cts 1an0 PROBYES 2 1 NS NPS 0 0 BU changed since last release and is now incorrect - 1an5 NO 2 2 C2 C2 9687366 9687366 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1an7 PROBYES 4 2 D2 C2 9636713 9636713 Paper says dimer - Interface geometry conserved with 1sei (58%) 1an8 PROBNOT 2 2 C2 C2 9253413 9253413 Paper thinks dimer is bioligocaly relevant 1anb PROBYES 2 1 C2 NPS 1554694 1554694 Trysin is monomeric 1anc PROBYES 2 1 C2 NPS 1554694 1554694 Trysin is monomeric -- Annotation transfered from 1anb 1and PROBYES 2 1 C2 NPS 8448149 8448149 Trysin is monomeric -- Annotation transfered from 1anb 1ane PROBYES 2 1 C2 NPS 8448149 0 Trysin is monomeric -- Annotation transfered from 1anb 1anf PROBNOT 1 1 NPS NPS 9309217 9309217 EcoCyc says monomer -- Annotation transfered from 1nl5 1ang YES 2 2 C2 C2 8159679 8159679 Human angiogenin is monomeric 1ank_1 PROBNOT 1 1 NPS NPS 7937733 0 BU changed since last release and is now corrected - SP and EcoCyc say monomer - automaticaly inferred from 1e4y 1ank_2 PROBNOT 1 1 NPS NPS 7937733 0 BU changed since last release and is now corrected - SP and EcoCyc say monomer - automaticaly inferred from 1e4y 1ann PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 1aow 1ant PROBNOT 2 2 C2 C2 8087553 8087553 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization -- Annotation transfered from 1jvq 1anv PROBYES 1 2 NPS NS 15299602 8632448 BU changed since last release and is now incorrect - Paper says: Dynamic light-scattering shows that the C-terminal domain is inde ed p olymeric in solution. - automaticaly inferred from 1adu 1anw_1 PROBNOT 1 1 NPS NPS 1446685 9398511 BU changed since last release and is now corrected - SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) - So no dimer - automaticaly inferred from 1hak 1anw_2 PROBNOT 1 1 NPS NPS 1446685 9398511 BU changed since last release and is now corrected - SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) - So no dimer - automaticaly inferred from 1hak 1anx_1 PROBNOT 1 1 NPS NPS 8254674 9398511 BU changed since last release and is now corrected - SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) - So no dimer - automaticaly inferred from 1hak 1anx_2 PROBNOT 1 1 NPS NPS 8254674 9398511 BU changed since last release and is now corrected - SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) - So no dimer - automaticaly inferred from 1hak 1anx_3 PROBNOT 1 1 NPS NPS 8254674 9398511 BU changed since last release and is now corrected - SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) - So no dimer - automaticaly inferred from 1hak 1ao5 YES 4 1 C2 NPS 9232643 9232643 BU changed since last release and is now incorrect - The physiological relevance of the mGK-13 dimer unclear. Although mGK-13 is monomeric in solution at a concentration of 1 mg/mL, the yield of purified mGK-13 indicates that a concentration in excess of 10 mg/mL occurs in the mouse submandibular glands. - might be a monomer dimer equilibrium 1aoa PROBNOT 1 1 NPS NPS 9302997 9302997 SwissProt says monomer 1aob NO 2 2 C2 C2 9687366 9687366 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1aoc PROBYES 2 1 NS NPS 9003754 9003754 Coagulogen is a soluble protein that has the potetial to self-oligomerize to form gel like matter. This is triggered by cleavage and removal of the peptide C, which uncover a hydrophobic surface. -- very interesting protein and function! 1aoe_1 PROBNOT 1 1 NPS NPS 9374515 9374515 BU changed since last release and is now corrected - Paper says nothing - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1ai9 1aoe_2 PROBNOT 1 1 NPS NPS 9374515 9374515 BU changed since last release and is now corrected - Paper says nothing - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1ai9 1aof NO 2 2 C2 C2 9311786 9311786 Homodimer -- Annotation transfered from 1h9y 1aog NO 2 2 C2 C2 8771196 8771196 Large interface and closely related dimer -- Annotation transfered from 1bzl 1aoj NO 2 2 C2 C2 9303002 9303002 SwissProt says homodimer -- Annotation transfered from 1i07 1aon NO 21 21 NPS C7 9285585 9285585 -- error in symmetry calculation, I dont know why 1aoq NO 2 2 C2 C2 9311786 9311786 Homodimer -- Annotation transfered from 1h9y 1aos NO 4 4 D2 D2 9256435 9256435 Interface geometry conserved with 1fur (22%) 1aow PROBNOT 1 1 NPS NPS 9405281 9405281 SP says monomer 1aox PROBYES 2 1 C2 NPS 9353312 9353312 Normaly forms heterodimers 1aoz PROBNOT 2 2 C2 C2 1548698 1548698 The dimer related about this crystallographic axis is suggested as the dimer present in solution. 1ap5 NO 4 4 D2 D2 9537987 9537987 Paper says tetramer -- Annotation transfered from 1n0j 1ap6 NO 4 4 D2 D2 9537987 9537987 Paper says tetramer -- Annotation transfered from 1n0j 1ap9 NO 3 3 C3 C3 9287223 9287223 SP says trimer -- Annotation transfered from 2brd 1apa PROBNOT 1 1 NPS NPS 7925458 7925458 SP says monomer 1apb NO 1 1 NPS NPS 2204627 2204627 EcoCyc says monomer -- Annotation transfered from 1abe 1apg PROBNOT 1 1 NPS NPS 1433290 9147041 Blocked ricin undergoes a pH-dependent reversible self-association, being predominantly dimeric at neutral pH and monomeric at acidic pH. 1apm NO 1 1 NPS NPS 15299526 0 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1apn NO 4 4 D2 D2 8749847 8749847 SP says tetramer -- Annotation transfered from 1cjp 1apt NO 1 1 NPS NPS -1 0 -- Annotation transfered from 1bxo 1apu NO 1 1 NPS NPS -1 0 -- Annotation transfered from 1bxo 1apv NO 1 1 NPS NPS 1567842 1567842 -- Annotation transfered from 1bxo 1apw NO 1 1 NPS NPS 1567842 1567842 -- Annotation transfered from 1bxo 1aq0 PROBYES 2 1 NS NPS 9452466 9452466 Paper says: Space group and unit cell dimensions are consistent with the presence of two protein molecules per asymmetric unit. does not mention an oligomer. 1aq1 NO 1 1 NPS NPS 9334743 9334743 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1aq2 NO 1 1 NPS NPS 9406547 9406547 Paper says: E. coli PCK is a monomeric, globular protein -- Annotation transfered from 1os1 1aq7 PROBNOT 1 1 NPS NPS -1 0 -- Annotation transfered from 1az8 1aq8 NO 3 3 C3 C3 9353305 9353305 -- Annotation transfered from 1as7 1aqb PROBNOT 1 1 NPS NPS 9757135 9757135 Serum retinol binding protein (RBP) is a monomeric protein of molecular weight 21,000 that transports vitamin A in the circulation 1aqc PROBYES 2 1 NS NPS 9321393 9321393 Paper shows a monomer 1aqe NO 2 2 C2 C2 9485359 9485359 Paper says dimer -- Annotation transfered from 1czj 1aqf_1 PROBNOT 4 4 D2 D2 9308890 8193145 BU changed since last release and is now corrected - 15299671 says tetramer - automaticaly inferred from 1pkn 1aqf_2 PROBNOT 4 4 D2 D2 9308890 8193145 BU changed since last release and is now corrected - 15299671 says tetramer - automaticaly inferred from 1pkn 1aql_1 NO 1 1 NPS NPS 9331420 9548741 Paper says monomer - automatic transfer from 2bce 1aql_2 NO 1 1 NPS NPS 9331420 9548741 Paper says monomer - automatic transfer from 2bce 1aqn NO 1 1 NPS NPS 2514787 2514787 -- Annotation transfered from 1yja 1aqp NO 1 1 NPS NPS 9275172 9275172 -- Annotation transfered from 6rsa 1aqu NA 2 2 C2 C2 9360604 9360604 I have not read the paper but my guess is that this is a wrong interface (the right one is in 1hy3). -- Annotation transfered from 1bo6 1aqv NO 2 2 C2 C2 1522586 1522586 -- Annotation transfered from 9gss 1aqw_1 NO 2 2 C2 C2 9351803 9398518 - automatic transfer from 9gss 1aqw_2 NO 2 2 C2 C2 9351803 9398518 - automatic transfer from 9gss 1aqx_1 NO 2 2 C2 C2 9351803 9398518 - automatic transfer from 9gss 1aqx_2 NO 2 2 C2 C2 9351803 9398518 - automatic transfer from 9gss 1aqy NA 2 2 C2 C2 9360604 9360604 I have not read the paper but my guess is that this is a wrong interface (the right one is in 1hy3). -- Annotation transfered from 1bo6 1ar0 NO 2 2 C2 C2 9368653 9368653 NTF2 eluted with an apparent Mr of 31 kDa consistent with its existing in solution as dimers. -- Annotation transfered from 1oun 1ar2 NO 2 2 C2 C2 9427009 9427009 Paper says dimer 1ar4 NO 4 4 D2 D2 -1 0 The overall structure of the SOD remains a compact tetrameter and is comparable to that at pH 6.1 no matter whether the pH increases or fluoride is added -- Annotation transfered from 1bsm 1ar5 NO 4 4 D2 D2 -1 0 The overall structure of the SOD remains a compact tetrameter and is comparable to that at pH 6.1 no matter whether the pH increases or fluoride is added -- Annotation transfered from 1bsm 1arg NO 2 2 C2 C2 7556224 7556224 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1arh NO 2 2 C2 C2 7556224 7556224 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1ari NO 2 2 C2 C2 7851426 7851426 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1arp PROBNOT 1 1 NPS NPS 8289254 8289254 Peroxidases seem to be monomeric in general -- Annotation transfered from 1gza 1ars NO 2 2 C2 C2 7798192 7798192 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1art NO 2 2 C2 C2 7798192 7798192 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1aru PROBNOT 1 1 NPS NPS 7665612 7665612 Peroxidases seem to be monomeric in general -- Annotation transfered from 1gza 1arv PROBNOT 1 1 NPS NPS 7665612 7665612 Peroxidases seem to be monomeric in general -- Annotation transfered from 1gza 1arw PROBNOT 1 1 NPS NPS 7665612 7665612 Peroxidases seem to be monomeric in general -- Annotation transfered from 1gza 1arx PROBNOT 1 1 NPS NPS 7665612 7665612 Peroxidases seem to be monomeric in general -- Annotation transfered from 1gza 1ary PROBNOT 1 1 NPS NPS 7665612 7665612 Peroxidases seem to be monomeric in general -- Annotation transfered from 1gza 1as0 PROBNOT 1 1 NPS NPS 9398294 9398294 Normally part of a heterotrimer, so apparently no homo-interaction. -- Annotation transfered from 1gdd 1as2 PROBNOT 1 1 NPS NPS 9398294 9398294 Normally part of a heterotrimer, so apparently no homo-interaction. -- Annotation transfered from 1gdd 1as3 PROBNOT 1 1 NPS NPS 9398294 9398294 Normally part of a heterotrimer, so apparently no homo-interaction. -- Annotation transfered from 1gdd 1as6 NO 3 3 C3 C3 9353305 9353305 -- Annotation transfered from 1as7 1as7 NO 3 3 C3 C3 9353305 9353305 1as8 NO 3 3 C3 C3 9353305 9353305 -- Annotation transfered from 1as7 1asa NO 2 2 C2 C2 0 0 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1asb NO 2 2 C2 C2 0 0 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1asc NO 2 2 C2 C2 0 0 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1asd NO 2 2 C2 C2 0 0 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1ase NO 2 2 C2 C2 0 0 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1asf NO 2 2 C2 C2 0 0 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1asg NO 2 2 C2 C2 0 0 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1ask NO 2 2 C2 C2 9368653 9368653 NTF2 eluted with an apparent Mr of 31 kDa consistent with its existing in solution as dimers. -- Annotation transfered from 1oun 1asl NO 2 2 C2 C2 8196059 8196059 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1asm NO 2 2 C2 C2 8196059 8196059 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1asn NO 2 2 C2 C2 8196059 8196059 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1aso PROBNOT 2 2 C2 C2 8478945 8478945 The dimer related about this crystallographic axis is suggested as the dimer present in solution. -- Annotation transfered from 1aoz 1asp PROBNOT 2 2 C2 C2 8478945 8478945 The dimer related about this crystallographic axis is suggested as the dimer present in solution. -- Annotation transfered from 1aoz 1asq PROBNOT 2 2 C2 C2 8478945 8478945 The dimer related about this crystallographic axis is suggested as the dimer present in solution. -- Annotation transfered from 1aoz 1asu NO 2 2 C2 C2 7563093 7563093 This dimer might be right but another form (with another interface), the one found in 1a5v (same sequence as this one), is similar to 1itg even though there is little seq similarity (30%). So Id say that the conserved interface is probably right. This one could be as well since SP say it is a homotetramer, but I believe more in the conserved one so for now I ll say this one is wrong. (PISA might be wrong too then). 1asv NO 2 2 C2 C2 7563093 7563093 Interface is conserved with 1itg even though seq sim is ~35% so I believe this interface is functionally relevant (plus it is known to oligomerize). - very interesting -- Annotation transfered from 1cxu 1asw PROBYES 2 2 C2 C2 7563093 7563093 This dimer might be right but another form (with another interface), the one found in 1a5v (same sequence as this one), is similar to 1itg even though there is little seq similarity (30%). So Id say that the conserved interface is probably right. This one could be as well since SP say it is a homotetramer, but I believe more in the conserved one so for now I ll say this one is wrong. (PISA might be wrong too then). 1at1 NO 12 12 D3 D3 2405902 2405902 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1at5 NO 1 1 NPS NPS 9571046 9571046 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1at6 NO 1 1 NPS NPS 9571046 9571046 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1ath PROBNOT 2 2 C2 C2 7656006 7656006 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization -- Annotation transfered from 1jvq 1atj YES 6 1 NS NPS 9406554 9406554 1atk NO 1 1 NPS NPS 9033588 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa 1atl PROBYES 2 1 C2 NPS 8078901 8078901 Papers say nothing and PISA says monomer -- Annotation transfered from 1dth 1atp NO 1 1 NPS NPS 15299527 0 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1atu PROBNOT 1 1 NPS NPS 8939743 8939743 Paper says nothing, forms a heterodimer with an apparent 1:1 ratio (1oph) and PISA says monomer -- Annotation transfered from 1oo8 1au0 NO 1 1 NPS NPS -1 0 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa -- Annotation transfered from 1atk 1au1 NA 2 2 NS NS 9342320 9342320 However, unlike the human IFN-alpha2b dimer, in which homologous surfaces form the interface, human IFN-beta dimerizes with contact surfaces from opposite sides of the molecule. - The crystal structures determined for many of these helical cytokines, as well as biochemical studies, show that some of them form dimers (IFN-γ, IL-10, MCSF, IL-5) with topologies suggesting that rearrangements at the genetic level have occurred that preserve the dimerization potential 1au2 NO 1 1 NPS NPS -1 0 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa -- Annotation transfered from 1atk 1au3 NO 1 1 NPS NPS 9733481 0 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa -- Annotation transfered from 1atk 1au4 NO 1 1 NPS NPS 9733481 0 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa -- Annotation transfered from 1atk 1au7 NO 2 2 C2 C2 9009203 9009203 BU changed since last release and is now corrected - Paper says homodimer 1au8 PROBNOT 1 1 NPS NPS 0 0 Paper says nothing - PISA says monomer -- Annotation transfered from 1cgh 1au9 NO 1 1 NPS NPS 2684274 2684274 -- Annotation transfered from 1yja 1auc PROBNOT 2 2 C2 C2 9369469 9369469 SP says dimer, paper too, interface geometry conserved with 1nsw (36%) - monomer dimer equilibrium -- Annotation transfered from 1aiu 1aug NO 4 4 D2 D2 10196127 10196127 Interface geometry conserved with 1a2z (36%) 1auj PROBNOT 1 1 NPS NPS 9341205 9341205 -- Annotation transfered from 1az8 1auk YES 1 2 NPS C2 9521684 9521684 All similar structures are dimers or octamers, and this appears to be right. -- Annotation transfered from 1e1z 1aun PROBNOT 1 1 NPS NPS 10047487 10047487 Thaumatin-like Zeamatin is a 22 kDa protein isolated from corn 1auv NO 4 4 D2 D2 9463376 9463376 Paper says: An ATP-stabilized tetramer of rSynI-ABC is observed during velocity sedimentation and size-exclusion chromatographic experiments. -- Annotation transfered from 1px2 1auw NO 4 4 D2 D2 9369472 9369472 Interface geometry conserved with 1fur (23%) -- Annotation transfered from 1tjw 1aux NO 4 4 D2 D2 9463376 9463376 Paper says: An ATP-stabilized tetramer of rSynI-ABC is observed during velocity sedimentation and size-exclusion chromatographic experiments. -- Annotation transfered from 1px2 1av4 NO 2 2 C2 C2 9405045 9405045 Interface geometry conserved with 1ksi (25%) -- Annotation transfered from 1sii 1av6 PROBNOT 1 1 NPS NPS 9660928 9660928 SP and PISA say monomer -- Annotation transfered from 1eam 1av7 NO 1 1 NPS NPS 9425066 9425066 -- Annotation transfered from 1be6 1avb NO 2 2 C2 C2 9582323 9582323 Paper says dimer 1avd NO 4 4 D2 D2 8515446 8515446 Avidin is a clear tetramer -- Annotation transfered from 2cam 1ave NO 4 4 D2 D2 8289264 8289264 Avidin is a clear tetramer -- Annotation transfered from 2cam 1avh_1 PROBNOT 1 1 NPS NPS 1311770 9398511 BU changed since last release and is now corrected - SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) - So no dimer - automaticaly inferred from 1hak 1avh_2 PROBNOT 1 1 NPS NPS 1311770 9398511 BU changed since last release and is now corrected - SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) - So no dimer - automaticaly inferred from 1hak 1avk NO 2 2 C2 C2 9405045 9405045 Interface geometry conserved with 1ksi (25%) -- Annotation transfered from 1sii 1avl NO 2 2 C2 C2 9405045 9405045 Interface geometry conserved with 1ksi (25%) -- Annotation transfered from 1sii 1avm NO 4 4 D2 D2 0 0 The overall structure of the SOD remains a compact tetrameter and is comparable to that at pH 6.1 no matter whether the pH increases or fluoride is added -- Annotation transfered from 1bsm 1avn PROBNOT 1 1 NPS NPS 9265618 9265618 9000633 says monomeric -- Annotation transfered from 1uga 1avr PROBNOT 1 1 NPS NPS 1311770 1311770 11099380SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) 1avs_1 PROBNOT 1 1 NPS NPS 9367759 0 - automatic transfer from 1ncx 1avs_2 PROBNOT 1 1 NPS NPS 9367759 0 - automatic transfer from 1ncx 1avt NO 1 1 NPS NPS 9425066 9425066 -- Annotation transfered from 1be6 1aw5 NO 8 8 D4 D4 9406553 9406553 Paper says octamer -- Annotation transfered from 1qml 1aw9 PROBYES 6 2 D3 C2 9417936 9417936 Paper does not talk about the hexamer and PISA also says dimer. 1awb NO 2 2 C2 C2 -1 8068620 - automatic transfer from 1imb 1awd PROBYES 2 1 C2 NPS 10545324 10545324 Seems monomeric - Plus all others that are similar are monomeric - paper says: as with all previously described ferredoxins, the protein is strongly anionic and the isoelectric point was determined as 3.7. No isoforms were detected. The molecular weight determined by sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS–PAGE) was very high, 20 kDa, similar to that of other ferredoxins with anomalous behaviour in polyacrylamide gels, and attributed to some ionic interaction with the gel matrix due to the low isoelectric point of ferredoxins. Gel filtration using a calibrated superose column and 0.25 M NaCl gave a mass of 14.6 kDa, which is still much higher than the molecular weight calculated from the amino acid sequence (10,196 Da). 1awi PROBYES 2 1 C2 NPS 9360613 9360613 SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio - paper says nothing about dimer 1awp PROBYES 2 1 NS NPS 9484218 9484218 Oligomeric state not mentioned - PISA says monomer 1awq PROBNOT 1 1 NPS NPS 9385632 9385632 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 1awr_1 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1awr_2 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1awr_3 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1awr_4 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1awr_5 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1awr_6 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1aws PROBNOT 1 1 NPS NPS 9385632 9385632 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 1awt_1 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1awt_2 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1awt_3 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1awt_4 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1awt_5 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1awt_6 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1awu PROBNOT 1 1 NPS NPS 9385632 9385632 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 1awv_1 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1awv_2 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1awv_3 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1awv_4 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1awv_5 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1awv_6 PROBNOT 1 1 NPS NPS 9385632 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1ax0 NO 2 2 C2 C2 9545381 9545381 1ax1 NO 2 2 C2 C2 9545381 9545381 -- Annotation transfered from 1ax0 1ax2 NO 2 2 C2 C2 9545381 9545381 -- Annotation transfered from 1ax0 1ax9 PROBNOT 1 1 NPS NPS 10089512 10089512 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1axa NO 2 2 C2 C2 9521105 9521105 -- Annotation transfered from 1ajx 1axb PROBNOT 1 1 NPS NPS 9485412 9485412 EcoCyc says monomer -- Annotation transfered from 1jwp 1axc NO 3 3 C3 C3 8861913 8861913 1axd NO 2 2 C2 C2 9417926 9417926 1axe NO 2 2 C2 C2 9371755 9371755 -- Annotation transfered from 8adh 1axg_1 PROBNOT 2 2 C2 C2 9371755 9132002 BU changed since last release and is now corrected - - automaticaly inferred from 1lde 1axg_2 PROBNOT 2 2 C2 C2 9371755 9132002 BU changed since last release and is now corrected - - automaticaly inferred from 1lde 1axm_1 PROBYES 2 1 C2 NPS 9655399 8652550 BU changed since last release and is now incorrect - SP says monomer - automaticaly inferred from 2afg 1axm_2 PROBYES 2 1 C2 NPS 9655399 8652550 BU changed since last release and is now incorrect - SP says monomer - automaticaly inferred from 2afg 1axm_3 PROBYES 2 1 C2 NPS 9655399 8652550 BU changed since last release and is now incorrect - SP says monomer - automaticaly inferred from 2afg 1axn PROBNOT 1 1 NPS NPS 8639653 8639653 PISA says monomer and related proteins are monomeric 1axq NO 1 1 NPS NPS -1 0 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1axr NO 2 2 C2 C2 -1 0 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1axw NO 2 2 C2 C2 0 0 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1axy NO 2 2 C2 C2 9545381 9545381 -- Annotation transfered from 1ax0 1axz NO 2 2 C2 C2 9545381 9545381 -- Annotation transfered from 1ax0 1ay2 PROBYES 2 2 C2 NS 7477282 7477282 In the pili the protein adopts a helical symmetry so a closed dimer cannot be the right assembly 1ay4 NO 2 2 C2 C2 9665848 9665848 PAper says dimer -- Annotation transfered from 2ay6 1ay5 NO 2 2 C2 C2 9665848 9665848 PAper says dimer -- Annotation transfered from 2ay6 1ay8 NO 2 2 C2 C2 9665848 9665848 PAper says dimer -- Annotation transfered from 2ay6 1aya_1 PROBNOT 1 1 NPS NPS 7521735 7521735 - automatic transfer from 1ayd 1aya_2 PROBNOT 1 1 NPS NPS 7521735 7521735 - automatic transfer from 1ayd 1ayb PROBNOT 1 1 NPS NPS 7521735 7521735 -- Annotation transfered from 1ayd 1ayc PROBNOT 1 1 NPS NPS 7521735 7521735 -- Annotation transfered from 1ayd 1ayd PROBNOT 1 1 NPS NPS 7521735 7521735 1ayf PROBYES 2 1 C2 NPS 9551550 9551550 Paper says nothing, PISA implies monomer 1ayi YES 2 1 C2 NPS 9639578 9639578 we found that Im7 only ever exists in solution as a monomer, even up to protein concentrations of 15 mg/ml 1ayl NO 1 1 NPS NPS 8599762 8599762 Paper says: E. coli PCK is a monomeric, globular protein -- Annotation transfered from 1os1 1ayo PROBYES 2 1 NS NPS 9634697 9634697 Paper says:The αMs exist as monomers, or as dimeric and tetrameric assemblies of approximately 180 kDa subunits 1ayp_1 PROBYES 2 1 C2 NPS 15299314 8979149 BU changed since last release and is now incorrect - Human PLA predominantly exists as a monomer - automaticaly inferred from 1poe 1ayp_2 PROBYES 2 1 C2 NPS 15299314 8979149 BU changed since last release and is now incorrect - Human PLA predominantly exists as a monomer - automaticaly inferred from 1poe 1ayp_3 PROBYES 2 1 C2 NPS 15299314 8979149 BU changed since last release and is now incorrect - Human PLA predominantly exists as a monomer - automaticaly inferred from 1poe 1ayu NO 1 1 NPS NPS 9405598 9405598 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa -- Annotation transfered from 1atk 1ayv NO 1 1 NPS NPS 9405598 9405598 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa -- Annotation transfered from 1atk 1ayw NO 1 1 NPS NPS 9405598 9405598 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa -- Annotation transfered from 1atk 1ayz_1 PROBNOT 1 1 NPS NPS 9497353 9497353 Paper says nothing, PISA says monomer -- monomeric state seems consistent across the different homologous proteins. 1ayz_2 PROBNOT 1 1 NPS NPS 9497353 9497353 Paper says nothing, PISA says monomer -- monomeric state seems consistent across the different homologous proteins. -- Annotation transfered from 1ayz_1 1ayz_3 PROBNOT 1 1 NPS NPS 9497353 9497353 Paper says nothing, PISA says monomer -- monomeric state seems consistent across the different homologous proteins. -- Annotation transfered from 1ayz_1 1az1 NO 1 1 NPS NPS 9405046 9405046 SwissProt and PISA say monomer -- Annotation transfered from 1ads 1az2 NO 1 1 NPS NPS 9405046 9405046 SwissProt and PISA say monomer -- Annotation transfered from 1ads 1az5 NO 2 2 C2 C2 9485411 9485411 1az8 PROBNOT 1 1 NPS NPS 0 0 1azb NA 2 1 C2 NPS 15299522 0 No clear info found -- Annotation transfered from 1azc 1azc NA 2 1 C2 NPS 15299522 0 No clear info found 1azd NO 4 4 D2 D2 9094437 9094437 SP says tetramer -- Annotation transfered from 1cjp 1azf NO 1 1 NPS NPS 9757106 9757106 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1azi NO 1 1 NPS NPS 9576852 9576852 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1azl PROBNOT 1 1 NPS NPS 9622492 9622492 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1f4p 1azm NO 1 1 NPS NPS 7932756 7932756 10529183 says monomer -- Annotation transfered from 1crm 1azn_1 PROBYES 2 1 C2 NPS 15299318 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 1azn_2 PROBYES 2 1 C2 NPS 15299318 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 1azr_1 PROBYES 2 1 C2 NPS 15299504 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 1azr_2 PROBYES 2 1 C2 NPS 15299504 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 1azt YES 2 1 C2 NPS 9395396 9395396 Paper says: Each asymmetric unit of the crystal contains a nonphysiological Gsalpha dimer oriented parallel to the a axis of the crystal. 1azu PROBNOT 1 1 NPS NPS -1 0 This is hard to believe but it seems that azurin is a monomeric protein! 1azv NO 2 2 C2 C2 9541385 9541385 Mammalian Cu,Zn SOD assembles into an unusually stable homodimer with exquisite substrate specificity. Interface conserved down to 50% (at least with 1jcv) -- Annotation transfered from 1n19 1azw NA 2 2 C2 C2 9427736 9427736 No evidence found - Email was sent 1azx_1 PROBYES 1 2 NPS C2 9405673 15342247 BU changed since last release and is now incorrect - 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization - automaticaly inferred from 1jvq 1azx_2 PROBYES 1 2 NPS C2 9405673 15342247 BU changed since last release and is now incorrect - 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization - automaticaly inferred from 1jvq 1b02 NO 2 2 C2 C2 10091656 10091656 -- Annotation transfered from 1bsf 1b07 PROBNOT 1 1 NPS NPS 9851931 9851931 Paper says nothing, related structures are monomers and PISA says monomer 1b0c YES 10 10 NR D5 10731422 10731422 Paper says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium -- A decamer this protein may be, but the structure of this decamer it is not. Look at 1bhc and tell me that this structure is correct! 1b0d NO 1 1 NPS NPS 11418760 11418760 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1b0e PROBNOT 1 1 NPS NPS 9651152 9651152 -- Annotation transfered from 1c1m 1b0f NO 1 1 NPS NPS 9651152 10581030 Neutrophil elastase is a monomeric glycoprotein 1b0o PROBNOT 2 2 C2 C2 9867826 9867826 SP says: Under physiological conditions beta-lactoglobulin exists as an equilibrium mixture of monomeric and dimeric forms -- Annotation transfered from 2blg 1b0t NO 1 1 NPS NPS 0 0 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1b0u PROBYES 2 1 NS NPS 9872322 9872322 The protein is dimeric in solution but the dimer found in this structure might not be biologicaly relevant (cf. 12150914). Although it seems that dimerization is ATP induced so the monomeric state is also right. -- ligand induced dimerization 1b0v_1 NO 1 1 NPS NPS 10593945 8132582 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. - automatic transfer from 1frm 1b0v_2 NO 1 1 NPS NPS 10593945 8132582 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. - automatic transfer from 1frm 1b0v_3 NO 1 1 NPS NPS 10593945 8132582 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. - automatic transfer from 1frm 1b0v_4 NO 1 1 NPS NPS 10593945 8132582 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. - automatic transfer from 1frm 1b0w_1 PROBNOT 2 2 C2 C2 9818054 9990143 BU changed since last release and is now corrected - - automaticaly inferred from 1qp1 1b0w_2 PROBNOT 2 2 C2 C2 9818054 9990143 BU changed since last release and is now corrected - - automaticaly inferred from 1qp1 1b0w_3 PROBNOT 2 2 C2 C2 9818054 9990143 BU changed since last release and is now corrected - - automaticaly inferred from 1qp1 1b0x NO 2 2 C2 C2 9886291 9886291 Paper says dimer but it is later questioned (10601296). -- good interesting example to show that you can see anything you want in crystals and that some people even publish that ... 1b0y PROBNOT 1 1 NPS NPS 10531472 10531472 The protein seem to be in a monomer dimer equilibrium (12077426 EPR and NMR studies have shown that HiPIPs might dimerize in the solution through their hydrophobic surfaces, a discovery that has led to important insights regarding the electron-transfer pathway) 1b11 YES 1 2 NPS C2 10651036 10651036 1b13 PROBNOT 1 1 NPS NPS 10216292 10216292 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1fhm 1b14 NO 2 2 C2 C2 9735295 9735295 Paper says dimer -- Annotation transfered from 1a4u 1b15 NO 2 2 C2 C2 10366509 10366509 Paper says dimer -- Annotation transfered from 1a4u 1b16 NO 2 2 C2 C2 10366509 10366509 Paper says dimer -- Annotation transfered from 1a4u 1b1b YES 1 2 NPS C2 9887269 9887269 Interface conserved down to 30% with 1on1 1b1c PROBNOT 1 1 NPS NPS 10048323 10048323 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins 1b1e NO 1 1 NPS NPS 9918722 9918722 Human angiogenin is monomeric -- Annotation transfered from 1h52 1b1i NO 1 1 NPS NPS 9918722 9918722 Human angiogenin is monomeric -- Annotation transfered from 1h52 1b1j NO 1 1 NPS NPS 9918722 9918722 Human angiogenin is monomeric -- Annotation transfered from 1h52 1b1y PROBNOT 1 1 NPS NPS 9918723 9918723 Paper implies monomer: The 3D structure of sweet potato b-amylase has shown the same molecular architecture, except for the tetrameric nature of this enzyme (Cheong et al., 1995). 1b1z PROBNOT 4 4 D2 D2 9878045 9878045 Tetramer might be relevant: Structural and mutational studies of SEB, SEC, SPEA, and TSST1 suggest MHC binding uses the sur face on the front of Domain 1.Since this sur face is blocked in the SPEA tetramer, tetramer–monomer equilibrium will likely modulate superantigenicity. The ability of factors to stabilize the tetramer could be employed to reduce the ability of SPEA to stimulate T-cell proliferation. -- Annotation transfered from 1ha5 1b20_1 YES 1 3 NPS C3 11914482 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1b20_2 YES 1 3 NPS C3 11914482 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1b20_3 YES 1 3 NPS C3 11914482 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1b21_1 YES 1 3 NPS C3 11914482 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1b21_2 YES 1 3 NPS C3 11914482 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1b21_3 YES 1 3 NPS C3 11914482 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1b23 NO 1 1 NPS NPS 10368282 9838020 BU changed since last release and is now corrected - EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa. - automatic transfer from 1ha3_1 1b25 NO 4 4 D2 D2 10024458 10024458 Paper says tetramer 1b2j PROBNOT 1 1 NPS NPS 10216292 10216292 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1fhm 1b2k YES 2 1 NS NPS 11418760 11418760 1b2l NO 2 2 C2 C2 10366509 10366509 Paper says dimer -- Annotation transfered from 1a4u 1b2r NO 1 1 NPS NPS 10651039 10651039 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1b2x_1 YES 1 3 NPS C3 11914482 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1b2x_2 YES 1 3 NPS C3 11914482 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1b2x_3 YES 1 3 NPS C3 11914482 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1b2z_1 YES 1 3 NPS C3 11914482 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1b2z_2 YES 1 3 NPS C3 11914482 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1b2z_3 YES 1 3 NPS C3 11914482 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1b37_1 PROBNOT 1 1 NPS NPS 10368296 10368296 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Paper says: PAO is a monomeric soluble protein with a molecular mass of about 53 kDa and a non-covalently bound FAD molecule as cofactor (and gives reference) - automaticaly inferred from 1b5q 1b37_2 PROBNOT 1 1 NPS NPS 10368296 10368296 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Paper says: PAO is a monomeric soluble protein with a molecular mass of about 53 kDa and a non-covalently bound FAD molecule as cofactor (and gives reference) - automaticaly inferred from 1b5q 1b37_3 PROBNOT 1 1 NPS NPS 10368296 10368296 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Paper says: PAO is a monomeric soluble protein with a molecular mass of about 53 kDa and a non-covalently bound FAD molecule as cofactor (and gives reference) - automaticaly inferred from 1b5q 1b38 NO 1 1 NPS NPS 10085115 10085115 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1b39 NO 1 1 NPS NPS 10085115 10085115 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1b3a_1 PROBYES 1 2 NPS C2 9889151 0 BU changed since last release and is now incorrect - Paper implies it is a dimer - automaticaly inferred from 1eqt 1b3a_2 PROBYES 1 2 NPS C2 9889151 0 BU changed since last release and is now incorrect - Paper implies it is a dimer - automaticaly inferred from 1eqt 1b3d PROBYES 2 1 NS NPS 10543949 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme 1b3k_1 PROBNOT 1 1 NPS NPS 10368279 10913251 Paper says nothing - Family mostly monomeric - PISA says monomer - automatic transfer from 1dvn 1b3k_2 PROBNOT 1 1 NPS NPS 10368279 10913251 Paper says nothing - Family mostly monomeric - PISA says monomer - automatic transfer from 1dvn 1b3k_3 PROBNOT 1 1 NPS NPS 10368279 10913251 Paper says nothing - Family mostly monomeric - PISA says monomer - automatic transfer from 1dvn 1b3k_4 PROBNOT 1 1 NPS NPS 10368279 10913251 Paper says nothing - Family mostly monomeric - PISA says monomer - automatic transfer from 1dvn 1b3r NO 4 4 D2 D2 10387078 10387078 SP says tetramer, interface geometry conserved among rat and human. 1b42 YES 2 1 C2 NPS 10377383 10377383 SP and PISA say monomer -- Annotation transfered from 3mct 1b43 PROBYES 2 1 C2 NPS 9778254 9778254 Paper implies monomer - PISA agrees 1b47 NA 3 1 NS NPS 10078535 10078535 Paper does not mention a trimer 1b48 NO 2 2 C2 C2 10508391 10508391 1b49 NO 2 2 C2 C2 10064578 10064578 1b4d YES 1 2 NPS C2 10211820 10211820 1b4e NO 8 8 D4 D4 10194344 10194344 Paper says octamer -- Annotation transfered from 1i8j 1b4f YES 16 2 NS C2 9933164 9933164 BU changed since last release and is now incorrect - Paper claims it can form oligomers but 10601296 (same author, five months later?!) claims that finaly it might be monomeric -- come on how did this guy publish that?? 1b4k NO 8 8 D4 D4 10356331 10356331 Paper says octamer 1b4l NO 2 2 C2 C2 10026301 10026301 SOD is a dimer -- Annotation transfered from 2jcw 1b4n NO 4 4 D2 D2 10024458 10024458 Paper says tetramer -- Annotation transfered from 1b25 1b4p NO 2 2 C2 C2 0 0 1b4s NO 6 6 D3 D3 10200157 10200157 SP, PISA and paper say hexamer 1b4t NO 2 2 C2 C2 10026301 10026301 SOD is a dimer -- Annotation transfered from 2jcw 1b4w PROBYES 4 2 D2 C2 10728829 9761847 Paper says dimer 1b4x NO 2 2 C2 C2 10708649 10708649 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1b56 PROBNOT 1 1 NPS NPS 10493790 10493790 Paper says nothing, PISA says monomer 1b57 NO 2 2 C2 C2 10080900 10080900 1b59 PROBNOT 1 1 NPS NPS 9812898 9812898 Paper says nothing, PISA says monomer -- Annotation transfered from 1b6a 1b5d YES 4 2 C2 C2 10064578 10064578 1b5e YES 4 2 C2 C2 10064578 10064578 -- Annotation transfered from 1b5d 1b5m PROBNOT 1 1 NPS NPS 8973214 8973214 Oligomeric state not mentioned - PISA says monomer 1b5o NO 2 2 C2 C2 11432784 11432784 -- Annotation transfered from 1gck 1b5p NO 2 2 C2 C2 11432784 11432784 -- Annotation transfered from 1gck 1b5q YES 3 1 NS NPS 10368296 10368296 BU changed since last release and is now incorrect - Paper says: PAO is a monomeric soluble protein with a molecular mass of about 53 kDa and a non-covalently bound FAD molecule as cofactor (and gives reference) 1b5s NO 60 60 Icos Icos 9990008 9990008 Paper says 60-mer -- interesting: paper to cite absolutely!! Also ask Aaron Klug for his paper about quasi-equivalence. 1b5t NA 3 2 NS C2 10201405 10201405 Paper says dimer: Human and other eukaryotic MTHFRs are dimeric enzymes composed of subunits of Mr 70,000−77,000. BUT Gel filtration was used to demonstrate that E. coli MTHFR is a tetrameric enzyme that dissociates to dimers rather than monomers on dilution. -- no tetramer found by PISA 1b5u NO 1 1 NPS NPS 10350481 10350481 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1b5v NO 1 1 NPS NPS 10350481 10350481 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1b5w NO 1 1 NPS NPS 10350481 10350481 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1b5x NO 1 1 NPS NPS 10350481 10350481 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1b5y NO 1 1 NPS NPS 10350481 10350481 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1b5z_1 YES 1 2 NPS NPS 10350481 10350481 BU changed since last release and is now incorrect - -- Annotation transfered from 1ckg 1b5z_2 YES 1 2 NPS NPS 10350481 10350481 BU changed since last release and is now incorrect - -- Annotation transfered from 1ckg 1b6a PROBNOT 1 1 NPS NPS 9812898 9812898 Paper says nothing, PISA says monomer 1b6d PROBNOT 2 2 C2 C2 10091599 10091599 1b6e YES 1 2 NPS C2 10023772 10023772 However, homodimeric CD94 has been found on the surface of certain transfected cell lines in which the expression of NKG2 is absent. Consistent with these observations, results from gel filtration and gel electrophoresis indicate that the extracellular portion of CD94 forms noncovalent dimers. 1b6g NO 1 1 NPS NPS 10393294 10393294 SP says monomer -- Annotation transfered from 1edb 1b6i NO 1 1 NPS NPS 10618384 10618384 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1b6j NO 2 2 C2 C2 10387041 10387041 -- Annotation transfered from 1ajx 1b6k NO 2 2 C2 C2 10387041 10387041 -- Annotation transfered from 1ajx 1b6l NO 2 2 C2 C2 10387041 10387041 -- Annotation transfered from 1ajx 1b6m NO 2 2 C2 C2 10387041 10387041 -- Annotation transfered from 1ajx 1b6p NO 2 2 C2 C2 10387041 10387041 -- Annotation transfered from 1ajx 1b6q NO 2 2 C2 C2 10404589 10404589 Rop is a homodimeric RNA-binding protein (Polisky, 1988) -- Annotation transfered from 1nkd 1b6r YES 2 2 NS C2 10569930 10569930 Interface geometry conserved with 1eyz (24%) 1b6s_1 PROBNOT 2 2 C2 C2 10569930 10569930 BU changed since last release and is now corrected - Interface geometry conserved with 1eyz (24%) - automaticaly inferred from 1b6r 1b6s_2 PROBNOT 2 2 C2 C2 10569930 10569930 BU changed since last release and is now corrected - Interface geometry conserved with 1eyz (24%) - automaticaly inferred from 1b6r 1b6t NO 6 6 D3 D3 10205156 10205156 paper says hexamer 1b6u PROBYES 2 1 C2 NPS 10196125 10196125 Paper does not speak about a dimer - identical structures are monomeric and associated paper also says monomeric 1b71 NO 2 2 C2 C2 10201393 10201393 -- Annotation transfered from 1lkm 1b78 NO 2 2 C2 C2 10404228 10404228 Both gel filtration and dynamic light-scattering studies show that Mj0226 protein forms a dimer under physiological conditions (data not shown). 1b7a PROBYES 2 1 C2 NPS 9782057 9782057 Nothing said in the paper - PISA says monomer. An email was sent to the authors 1b7g YES 2 4 C2 D2 10448043 10448043 Tetramer in paper 1b7l NO 1 1 NPS NPS 10469827 10469827 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1b7m NO 1 1 NPS NPS 10469827 10469827 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1b7n NO 1 1 NPS NPS 10469827 10469827 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1b7o NO 1 1 NPS NPS 10469827 10469827 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1b7p NO 1 1 NPS NPS 10469827 10469827 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1b7q NO 1 1 NPS NPS 10469827 10469827 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1b7r NO 1 1 NPS NPS 10469827 10469827 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1b7s NO 1 1 NPS NPS 10469827 0 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1b7v PROBNOT 1 1 NPS NPS 11052663 11052663 PAper says nothing, PISA says monomer -- Annotation transfered from 1c75 1b87 PROBYES 1 2 NPS C2 10378269 10378269 1bo4 (33% id) has similar domain geometry 1b88 YES 2 1 C2 NPS 10373358 10373358 Paper says: Unlike other TCR Valpha domains that have been studied in isolation, this one does not dimerize in solution at concentrations below 1 mM, and the crystal fails to show dimer contacts that are likely to be physiological. 1b8c PROBNOT 2 2 C2 C2 10545326 10545326 Sedimentation equilibrium analysis results show that the EF fragment exists in a monomer-dimer equilibrium when complexed with La3+ // This symmetry is conserved with 1b8c. Not very clear though -- Annotation transfered from 5cpv 1b8e PROBNOT 2 2 C2 C2 11168385 11168385 SP says: Under physiological conditions beta-lactoglobulin exists as an equilibrium mixture of monomeric and dimeric forms -- Annotation transfered from 2blg 1b8f NO 4 4 D2 D2 10220322 10220322 Paper says: the chain fold topology is similar to that of a family of tetrameric enzymes catalyzing the elimination of various groups from carboxylic acids, as for instance a hydroxyl by fumarase, ammonia by aspartase, or a guanidino group by argininosuccinate lyase. The avian eye lens protein -crystallin also belongs to this family as an inactive form of the latter enzyme. None of the sequences of these proteins is detectably homologous to histidase or phenylalanine ammonia-lyase. - interesting: have a look wether interface geometry is conserved or not 1b8g NO 2 2 C2 C2 10610793 10610793 -- Annotation transfered from 1m4n 1b8l PROBNOT 1 1 NPS NPS 10545326 10545326 1b8n YES 1 3 NPS C3 12463747 12463747 Paper says trimer 1b8o YES 1 3 NPS C3 11170405 11170405 Paper says trimer -- Annotation transfered from 1b8n Also from http://arginine.chem.cornell.edu/Structures/HumanPNP.html, The active form of human PNP is a trimer with a molecular weight of about 100 kDa. Phe159 from the neighboring monomer completes the hydrophobic environment of the bound purine base. 1b8p NO 2 2 C2 C2 10206992 10206992 Paper says dimer -- Annotation transfered from 1b8u 1b8r PROBNOT 1 1 NPS NPS 10545326 10545326 -- Annotation transfered from 1b8l 1b8u NO 2 2 C2 C2 10206992 10206992 Paper says dimer 1b8v NO 2 2 C2 C2 10206992 10206992 Paper says dimer -- Annotation transfered from 1b8u 1b8x YES 1 2 NPS C2 9774548 0 Should be dimeric 1b8y PROBNOT 1 1 NPS NPS 10422833 10422833 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme -- Annotation transfered from 1caq 1b8z NO 2 2 C2 C2 9757133 9757133 Domain Swapped dimer 1b92 PROBYES 1 2 NPS C2 10413462 10413462 The dimer is true and exists in the crystal as PISA finds it. -- Annotation transfered from 1b9d 1b99 NO 6 6 D3 D3 10353838 10353838 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1b9a PROBNOT 1 1 NPS NPS 10545326 10545326 -- Annotation transfered from 1b8l 1b9b NO 4 4 D2 D2 10591103 10591103 Paper says tetramer 1b9c YES 4 2 NS C2 11056031 11056031 1b9d PROBYES 1 2 NPS C2 10413462 10413462 The dimer is true and exists in the crystal as PISA finds it. 1b9f PROBYES 1 2 NPS C2 10413462 10413462 The dimer is true and exists in the crystal as PISA finds it. -- Annotation transfered from 1b9d 1b9h NO 2 2 C2 C2 10433690 10433690 Paper says dimer -- Annotation transfered from 1b9i 1b9i NO 2 2 C2 C2 10433690 10433690 Paper says dimer 1b9o PROBNOT 1 1 NPS NPS 10080897 10080897 SP says: Lactose synthase (LS) is a heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA). 1ba2_1 NO 1 1 NPS NPS 9641984 7982928 ribose ABC transporter, subunit B - monomer according to EcoCyc - automatic transfer from 1drj 1ba2_2 NO 1 1 NPS NPS 9641984 7982928 ribose ABC transporter, subunit B - monomer according to EcoCyc - automatic transfer from 1drj 1ba3 NO 1 1 NPS NPS 9788915 9788915 Paper says: the luciferase enzyme from the North American firefly Photinus pyralis was obtained from Promega as a 61-kDa recombinant monomeric protein. 1bag PROBNOT 1 1 NPS NPS 9514750 9514750 SP says monomer -- Annotation transfered from 1ua7 1ban_1 YES 1 3 NPS C3 8263918 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1ban_2 YES 1 3 NPS C3 8263918 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1ban_3 YES 1 3 NPS C3 8263918 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bao_1 YES 1 3 NPS C3 8263918 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bao_2 YES 1 3 NPS C3 8263918 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bao_3 YES 1 3 NPS C3 8263918 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bap NO 1 1 NPS NPS 2204627 2204627 EcoCyc says monomer -- Annotation transfered from 1abe 1bas PROBNOT 1 1 NPS NPS 1702556 1702556 SP says monomer 1baw PROBYES 6 3 D3 C3 10089349 10089349 They speak about a trimer but do not speak about a hexamer. I am not even sure that the trimer is biological. 1bay NO 2 2 C2 C2 9446594 9446594 1bb3_1 YES 1 2 NPS NPS 0 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 1bb3_2 YES 1 2 NPS NPS 0 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 1bb4_1 YES 1 2 NPS NPS 0 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 1bb4_2 YES 1 2 NPS NPS 0 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 1bb5_1 YES 1 2 NPS NPS 0 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 1bb5_2 YES 1 2 NPS NPS 0 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 1bb6 NO 1 1 NPS NPS 10089395 10089395 -- Annotation transfered from 1lmq 1bb7 NO 1 1 NPS NPS 10089395 10089395 -- Annotation transfered from 1lmq 1bb9 PROBYES 2 1 C2 NPS 9736607 9736607 Paper says nothing, PISA say monomer 1bbc NO 1 1 NPS NPS 2062381 2062381 Human PLA predominantly exists as a monomer -- Annotation transfered from 1kqu 1bbh PROBNOT 2 2 C2 C2 8230224 8230224 SP says homodimer 1bbp PROBYES 4 2 C2 C2 3430616 3430616 SP says tetramer - PISA too - Email response from 1lnm author: 1lnm is definitely a stable monomer (as checked by gel permeation chromatography). 1bbp is rather a dimer according to the biochemical data published by Huber and coworkers. 1bbs_1 PROBNOT 1 1 NPS NPS 1608447 1807356 BU changed since last release and is now corrected - - automaticaly inferred from 1rne 1bbs_2 PROBNOT 1 1 NPS NPS 1608447 1807356 BU changed since last release and is now corrected - - automaticaly inferred from 1rne 1bbz_1 PROBNOT 1 1 NPS NPS 9698566 7664083 BU changed since last release and is now corrected - PISA says monomer, SH3 domain are functional as monomers - automaticaly inferred from 1abq 1bbz_2 PROBNOT 1 1 NPS NPS 9698566 7664083 BU changed since last release and is now corrected - PISA says monomer, SH3 domain are functional as monomers - automaticaly inferred from 1abq 1bbz_3 PROBNOT 1 1 NPS NPS 9698566 7664083 BU changed since last release and is now corrected - PISA says monomer, SH3 domain are functional as monomers - automaticaly inferred from 1abq 1bbz_4 PROBNOT 1 1 NPS NPS 9698566 7664083 BU changed since last release and is now corrected - PISA says monomer, SH3 domain are functional as monomers - automaticaly inferred from 1abq 1bc0 PROBNOT 1 1 NPS NPS 9609693 9609693 SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1n42 1bc1 PROBNOT 1 1 NPS NPS 9609693 9609693 SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1n42 1bc2 YES 2 1 C2 NPS 9730812 9730812 there is no evidence for dimerization of the enzyme in solution. 1bc3 PROBNOT 1 1 NPS NPS 9609693 9609693 SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1n42 1bc7 NO 1 1 NPS NPS 9734357 9734357 Paper implies monomeric: The observation that transcription factors with little sequence homology use similar scaffolds to recognize DNA suggests that the winged helix-turn-helix topology may be a highly efficient way for a monomeric protein subunit to recognize DNA. 1bc8 NO 1 1 NPS NPS 9734357 9734357 Paper implies monomeric: The observation that transcription factors with little sequence homology use similar scaffolds to recognize DNA suggests that the winged helix-turn-helix topology may be a highly efficient way for a monomeric protein subunit to recognize DNA. -- Annotation transfered from 1bc7 1bcd PROBNOT 1 1 NPS NPS 8070585 8070585 9000633 says monomeric -- Annotation transfered from 1uga 1bcf PROBNOT 24 24 Octa Octa 7664064 7664064 BU changed since last release and is now corrected - SP says 24-mer -- Symmetry problem? check 1bcg PROBYES 2 1 C2 NPS 9753689 9753689 Paper not linked, PISA says monomer 1bck PROBNOT 1 1 NPS NPS 9769216 9769216 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 1bcm YES 2 4 C2 D2 7628012 7628012 1bco YES 1 4 NPS D2 7628012 7628012 1bcw PROBNOT 1 1 NPS NPS 9609693 9609693 SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1n42 1bcx PROBNOT 1 1 NPS NPS 8019418 8019418 Paper says nothing and PISA says monomer -- Annotation transfered from 1xnb 1bcy PROBNOT 1 1 NPS NPS 9609693 9609693 SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1n42 1bcz PROBNOT 1 1 NPS NPS 9609693 9609693 SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1n42 1bd3 NO 4 4 D2 D2 9628859 9628859 Interface geometry conserved with 1o5o (40%) -- Annotation transfered from 1jlr 1bd4 NO 4 4 D2 D2 9628859 9628859 Interface geometry conserved with 1o5o (40%) -- Annotation transfered from 1jlr 1bd7 NO 2 2 C2 C2 9655330 9655330 True dimer but there is a SCOP error: should contain two domains and contains one only! 1bd9 PROBNOT 2 2 C2 C2 9782050 9782050 Paper says: Some evidence for the dimerisation of PEBP in solution has been observed from gel electrophoresis and fluorescence studies (data not shown), implying that the dimer observed in the crystal (see Figure 3a) may represent the functional form of the protein. This idea is further supported by the considerable solvent-accessible surface area buried between the two monomers in the dimer -- VERY INTERESTING AS A HUMAN HOMOLOG SEEMS MONOMERIC!!! 1bdb NO 4 4 D2 D2 9655331 9655331 Paper says tetramer 1bdj_1 PROBNOT 1 1 NPS NPS 10393292 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 1bdl NO 2 2 C2 C2 9692985 9692985 -- Annotation transfered from 1ajx 1bdm PROBNOT 2 2 C2 C2 8471603 0 SP says dimer -- Annotation transfered from 1bmd 1bdq NO 2 2 C2 C2 9692985 9692985 -- Annotation transfered from 1ajx 1bdr NO 2 2 C2 C2 9692985 9692985 -- Annotation transfered from 1ajx 1bdu NO 2 2 C2 C2 9687366 9687366 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1bdy NA 2 2 NS NS 9687370 9687370 1be0 NO 1 1 NPS NPS 9790663 9790663 SP says monomer -- Annotation transfered from 1edb 1be4 PROBNOT 6 6 D3 D3 9760230 9760230 SP says hexamer 1be6 NO 1 1 NPS NPS 9789015 9789015 1be7 PROBYES 3 1 C3 NPS -1 0 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1iro 1be8 NO 1 1 NPS NPS 9789015 9789015 -- Annotation transfered from 1be6 1bed NA 2 1 C2 NPS 9149147 9149147 It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant 1bee NO 1 1 NPS NPS 9790663 9790663 SP says monomer -- Annotation transfered from 1edb 1bef PROBNOT 1 1 NPS NPS 10026173 10026173 Paper mention s heterodimers but no homodimer or any other oligomer - PISA says monomer 1beh_1 PROBYES 1 2 NPS C2 9782050 9782050 BU changed since last release and is now incorrect - Paper says: Some evidence for the dimerisation of PEBP in solution has been observed from gel electrophoresis and fluorescence studies (data not shown), implying that the dimer observed in the crystal (see Figure 3a) may represent the functional form of the protein. This idea is further supported by the considerable solvent-accessible surface area buried between the two monomers in the dimer -- VERY INTERESTING AS A HUMAN HOMOLOG SEEMS MONOMERIC!!! - automaticaly inferred from 1bd9 1beh_2 PROBYES 1 2 NPS C2 9782050 9782050 BU changed since last release and is now incorrect - Paper says: Some evidence for the dimerisation of PEBP in solution has been observed from gel electrophoresis and fluorescence studies (data not shown), implying that the dimer observed in the crystal (see Figure 3a) may represent the functional form of the protein. This idea is further supported by the considerable solvent-accessible surface area buried between the two monomers in the dimer -- VERY INTERESTING AS A HUMAN HOMOLOG SEEMS MONOMERIC!!! - automaticaly inferred from 1bd9 1bej PROBNOT 1 1 NPS NPS 0 0 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1bek PROBNOT 1 1 NPS NPS 0 0 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1bel NO 1 1 NPS NPS 15299907 0 -- Annotation transfered from 6rsa 1bem PROBNOT 1 1 NPS NPS 0 0 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1beo PROBYES 2 1 C2 NPS 8994969 8994969 Out of the three almost identical proteins, no paper mentions a dimer, PISA says dimer for one only so Ill say monomer for all of them. 1bep PROBNOT 1 1 NPS NPS 0 0 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1beq PROBNOT 1 1 NPS NPS 0 0 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1bes PROBNOT 1 1 NPS NPS 0 0 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1bet PROBNOT 2 2 C2 C2 1956407 1956407 SP says dimer 1beu NO 4 4 C2 C2 9692955 9692955 Paper says a2b2 -- Annotation transfered from 2wsy 1bex PROBYES 2 1 C2 NPS 10089343 10089343 This is hard to believe but it seems that azurin is a monomeric protein! 1bez NO 1 1 NPS NPS 9790663 9790663 SP says monomer -- Annotation transfered from 1edb 1bf3 NO 2 2 C2 C2 9578477 9578477 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1bfd NO 4 4 D2 D2 9665697 9665697 Interface geometry conserved with 1ovm (25%) 1bff PROBNOT 1 1 NPS NPS 15299950 0 SP says monomer -- Annotation transfered from 1bas 1bfg PROBNOT 1 1 NPS NPS 1769963 1769963 SP says monomer -- Annotation transfered from 1bas 1bfk NO 1 1 NPS NPS 9675126 9675126 -- Annotation transfered from 1be6 1bfn PROBNOT 1 1 NPS NPS 9677422 9677422 SP says monomer -- Annotation transfered from 1v3i 1bfp NO 1 1 NPS NPS 9245407 9245407 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1bfr NO 24 24 Octa Octa 9867433 9867433 SP says 24-mer - Interface geometry conserved with 1jgc (49%) 1bfu NO 1 1 NPS NPS 9675126 9675126 -- Annotation transfered from 1be6 1bg0 NO 1 1 NPS NPS 9671698 9671698 Paper says: Arginine kinase is widespread in invertebrates and may be the primordial enzyme because of its widely available substrate, monomeric structure, and presence in protozoa -- interesting: very good family for QS evolution (close monomer, dimer and octamer) -- Annotation transfered from 1p52 1bg2 NO 1 1 NPS NPS 8606779 8606779 Missing dimerization coil-coil -- Annotation transfered from 1mkj 1bg5 NO 2 2 C2 C2 9668035 9668035 1bg7 NO 24 24 Octa Octa 9668036 9668036 Interface geometry conserved with 1lb3 (56%) 1bg9 YES 2 1 C2 NPS 9571044 9571044 alpha-Amylases (a-1,4 glucan-4-glucanohydrolase, EC 3.2.1.1) are monomeric enzymes that catalyse the hydrolysis of internal a-D-(1,4) glucosidic linkages in starch and related oligo- and polysaccharides with release of malto-oligosaccharides and glucose in the alpha-anomeric form. 1bga PROBNOT 8 8 D4 D4 9466926 9466926 Biochemical characterization of BglA showed that the native protein is an intracellular enzyme with an octameric configuration and a molecular mass of about 400,000 Da [Sanz-Aparicio et al 1994]. -- Annotation transfered from 1tr1 1bgg PROBNOT 8 8 D4 D4 9466926 9466926 Biochemical characterization of BglA showed that the native protein is an intracellular enzyme with an octameric configuration and a molecular mass of about 400,000 Da [Sanz-Aparicio et al 1994]. -- Annotation transfered from 1tr1 1bgi NO 1 1 NPS NPS 10089401 10089401 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1bgj NO 2 2 C2 C2 9694855 9694855 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1bgn NO 2 2 C2 C2 9694855 9694855 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1bgo NO 1 1 NPS NPS -1 0 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa -- Annotation transfered from 1atk 1bgp PROBYES 2 1 C2 NPS 9442067 9442067 Nothing about a dimer, PISA says monomer 1bgq NO 2 2 C2 C2 9925731 9925731 -- Annotation transfered from 1a4h 1bgt PROBNOT 1 1 NPS NPS 8062817 8062817 SP says monomer 1bgu PROBNOT 1 1 NPS NPS 8062817 8062817 SP says monomer -- Annotation transfered from 1bgt 1bh0 PROBNOT 3 3 C3 C3 9667960 9667960 171582 implies it might be biologicaly relevant 1bh2 PROBNOT 1 1 NPS NPS 9705312 9705312 Normally part of a heterotrimer, so apparently no homo-interaction. -- Annotation transfered from 1gdd 1bh3 NO 3 3 C3 C3 9684893 9684893 Interface geometry conserved with 1gfn (20%) -- Annotation transfered from 1prn 1bh5_1 NO 2 2 C2 C2 9705294 10521255 Interface geometry conserved with 1kll (28%) -- interesting: only case I know where two domain swapped proteins diverge and stay swapped. - automatic transfer from 1qin 1bh5_2 NO 2 2 C2 C2 9705294 10521255 Interface geometry conserved with 1kll (28%) -- interesting: only case I know where two domain swapped proteins diverge and stay swapped. - automatic transfer from 1qin 1bhc NO 10 10 D5 D5 10089400 10089400 paper says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium -- Annotation transfered from 1bz5 1bhf PROBNOT 1 1 NPS NPS 9685372 9685372 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 -- Annotation transfered from 1lkk 1bhh PROBYES 2 1 NS NPS 9685372 9685372 1bhj NO 4 4 D2 D2 9655336 9655336 Paper says tetramer -- Annotation transfered from 1d2h 1bhl NO 2 2 C2 C2 9735293 9735293 Often described as a dimer (sometimes tetramer), and convincingly a similar dimer (same interface) is found in 1a5v (30% id). -- Annotation transfered from 1itg 1bhn PROBNOT 6 6 D3 D3 10329774 10329774 SP says hexamer -- Annotation transfered from 1be4 1bho PROBYES 2 1 C2 NPS 9687375 9687375 Normally forms heterodimer - this contact is too small to be biological -- Annotation transfered from 1bhq 1bhp YES 4 2 C4 D2 15299761 0 Interface geometry seems conserved with 2plh 1bhq PROBYES 2 1 C2 NPS 9687375 9687375 Normally forms heterodimer - this contact is too small to be biological 1bhs NO 2 2 C2 C2 7663947 7663947 Paper says dimer -- Annotation transfered from 3dhe 1bhw NO 4 4 D2 D2 10089406 10089406 -- Annotation transfered from 5xin 1bhy NO 2 2 C2 C2 10089406 10089406 Paper says dimer -- Annotation transfered from 1ojt 1bhz NO 1 1 NPS NPS 10089406 10089406 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1bi0 PROBYES 1 2 NPS C2 9712865 9712865 Identicals are dimers and PISa says dimer 1bi1 PROBYES 1 2 NPS C2 9712865 9712865 Identicals are dimers and PISa says dimer -- Annotation transfered from 1bi0 1bi4 YES 3 2 NS C2 9735293 9735293 BU changed since last release and is now incorrect - - automaticaly inferred from 1bl3 1bi5 NO 2 2 C2 C2 10426957 10426957 BU changed since last release and is now corrected - bad reconstruction 1bi8 YES 4 1 C2 NPS 9751050 9751050 Paper says monomer 1bi9 NO 4 4 D2 D2 10320326 10320326 Interface geometry conserved with 1uxr (31%) 1bic PROBNOT 1 1 NPS NPS 8451242 8451242 9000633 says monomeric -- Annotation transfered from 1uga 1bid NO 2 2 C2 C2 9687366 9687366 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1bil PROBYES 2 1 NS NPS 7493993 7493993 -- Annotation transfered from 1bim 1bim PROBYES 2 1 NS NPS 7493993 7493993 1bio PROBNOT 1 1 NPS NPS 9753554 9753554 -- Annotation transfered from 1dic 1bis NO 2 2 C2 C2 9689049 9689049 Often described as a dimer (sometimes tetramer), and convincingly a similar dimer (same interface) is found in 1a5v (30% id). -- Annotation transfered from 1itg 1bit PROBNOT 1 1 NPS NPS 15299802 0 -- Annotation transfered from 1utm 1biu_1 PROBNOT 2 2 C2 C2 9689049 9735293 BU changed since last release and is now corrected - - automaticaly inferred from 1bl3 1biu_2 PROBNOT 2 2 C2 C2 9689049 9735293 BU changed since last release and is now corrected - - automaticaly inferred from 1bl3 1biw PROBYES 2 1 C2 NPS 9873489 9873489 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme -- Annotation transfered from 1hfs 1biz NO 2 2 C2 C2 9689049 9689049 Often described as a dimer (sometimes tetramer), and convincingly a similar dimer (same interface) is found in 1a5v (30% id). -- Annotation transfered from 1itg 1bj4 YES 1 4 NPS D2 9753690 9753690 Paper describes a homotetramer 1bj7 PROBNOT 1 1 NPS NPS 9891000 9891000 Paper implies it should be monomeric but no clear evidence given. PISA also says monomer 1bj9 PROBNOT 1 1 NPS NPS 0 0 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1bje NO 1 1 NPS NPS 9576852 9576852 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1bjf NO 2 2 C2 C2 9886296 9886296 Gel-permeation chromatography studies show that bovine neurocalcin exists as a homodimer in solution. 1bjg NO 2 2 C2 C2 9753479 9753479 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1bjk NO 1 1 NPS NPS 9922134 9922134 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1bjm NO 2 2 C2 C2 8692936 8692936 The three identical structures have a different dimeric packing! cf. paper -- interessting 1bjr PROBNOT 1 1 NPS NPS 9741842 9741842 -- Annotation transfered from 1p7v 1bju PROBNOT 1 1 NPS NPS 9836602 0 -- Annotation transfered from 1az8 1bjv PROBNOT 1 1 NPS NPS 9836602 0 -- Annotation transfered from 1az8 1bjw NO 2 2 C2 C2 10029535 10029535 -- Annotation transfered from 1gck 1bk0 PROBNOT 1 1 NPS NPS 9194566 9194566 No info was found, PISA says monomer. I also think it should be. -- Annotation transfered from 1uzw 1bk2 PROBNOT 1 1 NPS NPS 9699637 9699637 -- Annotation transfered from 1neg 1bk4 YES 4 4 NS D2 10089399 10089399 Paper says: Fru-1,6-Pases are homotetramers, and the rabbit liver protein crystallizes in space group I222 1bk5 NO 2 2 C2 C2 9695948 9695948 Paper says: The protein forms a homodimer in the crystals, and this self-association has implications for a possible autoinhibitory mechanism. [...]. Kapα50 appears to be homodimeric in aqueous solutions at a concentration of 1 mg/ml, as seen by dynamic light scattering. 1bk6_1 PROBYES 1 2 NPS C2 9695948 9695948 Paper says: The protein forms a homodimer in the crystals, and this self-association has implications for a possible autoinhibitory mechanism. [...]. Kapα50 appears to be homodimeric in aqueous solutions at a concentration of 1 mg/ml, as seen by dynamic light scattering. 1bk6_2 PROBYES 1 2 NPS C2 9695948 9695948 Paper says: The protein forms a homodimer in the crystals, and this self-association has implications for a possible autoinhibitory mechanism. [...]. Kapα50 appears to be homodimeric in aqueous solutions at a concentration of 1 mg/ml, as seen by dynamic light scattering. -- Annotation transfered from 1bk6_1 1bk7 PROBNOT 1 1 NPS NPS 10446375 10446375 No clear evidence was found. PISA says monomer -- Annotation transfered from 1uca 1bk9 PROBNOT 1 1 NPS NPS 9663694 9663694 SP says monomer 1bkb NA 4 4 C4 C4 9753699 9753699 Paper says: The unmodified protein is found either as a dimer or as a tetramer in solution (as determined by dynamic light scattering, data not shown), but the interactions found within the crystal are almost certainly too tenuous to be relevant to the form found in solution 1bkf YES 2 1 C2 NPS -1 0 Normally monomeric in solution - But very interesting: one mutation (F36M) transforms it into an inducible dimer. Isnt that so interesting? It thus also shows that it can be very simple to form a heterointerfaces, and that a high proportion of supposedly errors in the BU can reflect a potential high affinity (given that 1/2 mutations are introduced) - very nice example! -- Annotation transfered from 2fke 1bkg_1 NO 2 2 C2 C2 10029535 11432784 - automatic transfer from 1gck 1bkg_2 NO 2 2 C2 C2 10029535 11432784 - automatic transfer from 1gck 1bkh_1 NO 8 8 D4 D4 9724714 10336378 Paper says octamer - automatic transfer from 2muc 1bkh_2 NO 8 8 D4 D4 9724714 10336378 Paper says octamer - automatic transfer from 2muc 1bkl YES 2 1 C2 NPS 0 6254988 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution 1bkm NO 1 1 NPS NPS -1 0 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1bko_1 NO 2 2 C2 C2 9778348 9778348 - automatic transfer from 1bsf 1bko_2 NO 2 2 C2 C2 9778348 9778348 - automatic transfer from 1bsf 1bkp NO 2 2 C2 C2 9778348 9778348 -- Annotation transfered from 1bsf 1bks NO 4 4 C2 C2 0 0 Paper says a2b2 -- Annotation transfered from 2wsy 1bkw YES 1 2 NPS C2 7628466 7628466 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 1cc6 1bkx NO 1 1 NPS NPS 9261084 9261084 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1bky YES 2 1 C2 NPS 10377383 10377383 SP and PISA say monomer -- Annotation transfered from 3mct 1bkz YES 2 1 C2 NPS 9760227 9760227 Paper says: The hGal-7 molecule crystallizes as a dimer, although in solution it is known to exist as a monomer unlike most other mammalian galectins, except Gal-10 (6). -- Annotation transfered from 5gal 1bl3 YES 6 2 NS C2 9735293 9735293 1bl4 YES 2 1 C2 NPS 9724721 9724721 Normally monomeric in solution - But very interesting: one mutation (F36M) transforms it into an inducible dimer. Isnt that so interesting? It thus also shows that it can be very simple to form a heterointerfaces, and that a high proportion of supposedly errors in the BU can reflect a potential high affinity (given that 1/2 mutations are introduced) - very nice example! -- Annotation transfered from 2fke 1bl6 PROBNOT 1 1 NPS NPS 9753691 9753691 -- Annotation transfered from 1kv1 1bl7 PROBNOT 1 1 NPS NPS 9753691 9753691 -- Annotation transfered from 1kv1 1blb_1 PROBYES 4 2 D2 C2 8120900 12084052 B2-crystallin is a dimer in solution -- very interesting review: about evolution of oligomers! - automatic transfer from 2bb2 1blb_2 PROBYES 4 2 D2 C2 8120900 12084052 B2-crystallin is a dimer in solution -- very interesting review: about evolution of oligomers! - automatic transfer from 2bb2 1blc PROBYES 2 1 C2 NPS 1569569 1569569 Class A betalactamase are apparently monomeric in solution (said in paper) -- Annotation transfered from 1kgf 1blh PROBYES 2 1 C2 NPS 8230196 8230196 Class A betalactamase are apparently monomeric in solution (said in paper) -- Annotation transfered from 1kgf 1bli PROBNOT 1 1 NPS NPS 9551551 9551551 SP says monomer 1bll NO 6 6 D3 D3 8357796 8357796 Interface geometry conserved with 1gyt (30%) 1blp PROBYES 2 1 C2 NPS 1892849 1892849 Class A betalactamase are apparently monomeric in solution (said in paper) -- Annotation transfered from 1kgf 1blz PROBNOT 1 1 NPS NPS 9194566 9194566 No info was found, PISA says monomer. I also think it should be. -- Annotation transfered from 1uzw 1bm1 NO 3 3 C3 C3 10393291 10393291 SP says trimer -- Annotation transfered from 2brd 1bm2 NO 1 1 NPS NPS 10090780 10090780 -- Annotation transfered from 1zfp 1bm7 NO 4 4 D2 D2 9789022 9789022 transthyretin is tetrameric -- Annotation transfered from 1fh2 1bma PROBNOT 1 1 NPS NPS 7604279 7604279 -- Annotation transfered from 1c1m 1bmb NO 1 1 NPS NPS 10090780 10090780 -- Annotation transfered from 1zfp 1bmc NO 1 1 NPS NPS 7588620 7588620 -- Annotation transfered from 1bvt 1bmd PROBNOT 2 2 C2 C2 8471603 8471603 SP says dimer 1bmk PROBNOT 1 1 NPS NPS 9753691 9753691 -- Annotation transfered from 1kv1 1bml PROBYES 4 2 C2 NPS 9733510 9733510 Paper does not speak about a dimer of heterodimer. 1bmz PROBYES 2 4 C2 D2 9789022 9789022 All dimers similar to that one are found to be tetramers by PISA. Because the native structure is tetrameric, dimer are certainly mistakes 1bn1 PROBNOT 1 1 NPS NPS 9865942 9865942 9000633 says monomeric -- Annotation transfered from 1uga 1bn3 PROBNOT 1 1 NPS NPS 9865942 9865942 9000633 says monomeric -- Annotation transfered from 1uga 1bn4 PROBNOT 1 1 NPS NPS 9865942 9865942 9000633 says monomeric -- Annotation transfered from 1uga 1bn5 PROBNOT 1 1 NPS NPS 9812898 9812898 Paper says nothing, PISA says monomer -- Annotation transfered from 1b6a 1bn6 PROBNOT 1 1 NPS NPS 10587433 10587433 Paper mentions size exclusion column but no oligomer, PISA says monomer 1bn7 PROBNOT 1 1 NPS NPS 10587433 10587433 Paper mentions size exclusion column but no oligomer, PISA says monomer -- Annotation transfered from 1bn6 1bne_1 YES 1 3 NPS C3 7473729 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bne_2 YES 1 3 NPS C3 7473729 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bne_3 YES 1 3 NPS C3 7473729 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bnf_1 YES 1 3 NPS C3 7473729 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bnf_2 YES 1 3 NPS C3 7473729 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bnf_3 YES 1 3 NPS C3 7473729 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bng_1 YES 1 3 NPS C3 7473729 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bng_2 YES 1 3 NPS C3 7473729 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bng_3 YES 1 3 NPS C3 7473729 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bni_1 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bni_2 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bni_3 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bnj_1 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bnj_2 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bnj_3 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bnm PROBNOT 1 1 NPS NPS 9865942 9865942 9000633 says monomeric -- Annotation transfered from 1uga 1bnn PROBNOT 1 1 NPS NPS 9865942 9865942 9000633 says monomeric -- Annotation transfered from 1uga 1bnq PROBNOT 1 1 NPS NPS 9865942 9865942 9000633 says monomeric -- Annotation transfered from 1uga 1bns_1 YES 1 3 NPS C3 8263918 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bns_2 YES 1 3 NPS C3 8263918 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bns_3 YES 1 3 NPS C3 8263918 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bnt PROBNOT 1 1 NPS NPS 9865942 9865942 9000633 says monomeric -- Annotation transfered from 1uga 1bnu PROBNOT 1 1 NPS NPS 9865942 9865942 9000633 says monomeric -- Annotation transfered from 1uga 1bnv PROBNOT 1 1 NPS NPS 9865942 9865942 9000633 says monomeric -- Annotation transfered from 1uga 1bnw PROBNOT 1 1 NPS NPS 9865942 9865942 9000633 says monomeric -- Annotation transfered from 1uga 1bo4 PROBNOT 2 2 C2 C2 9727487 9727487 Paper says why they think its a dimer: a related enzyme, human spermidine/spermine NAT, has been shown to act as a dimer. We have shown that recombinant ovine serotonin NAT is a dimer at a concentration of about 1 mg/ml using dynamic light scattering. 1bo5 YES 2 4 C2 D2 9843423 9843423 1bo6 NA 2 2 C2 C2 9360604 9360604 I have not read the paper but my guess is that this is a wrong interface (the right one is in 1hy3). 1bo7 NO 2 2 C2 C2 10653645 10653645 SP says homodimer -- Annotation transfered from 4tms 1bo8 NO 2 2 C2 C2 10653645 10653645 SP says homodimer -- Annotation transfered from 4tms 1boa PROBNOT 1 1 NPS NPS 9812898 9812898 Paper says nothing, PISA says monomer -- Annotation transfered from 1b6a 1bof PROBNOT 1 1 NPS NPS 9772163 9772163 Normally part of a heterotrimer, so apparently no homo-interaction. -- Annotation transfered from 1gdd 1boo PROBYES 1 2 NPS C2 9207015 9207015 Paper says dimer but doesnt show it. -- PISA doesnt find it 1boq NO 1 1 NPS NPS 9724517 9724517 9846867 says monomer -- Annotation transfered from 1p05 1bot_1 YES 2 4 C2 D2 9843423 9843423 - automatic transfer from 1bo5 1bot_2 YES 2 4 C2 D2 9843423 9843423 - automatic transfer from 1bo5 1box PROBNOT 1 1 NPS NPS 9819211 9819211 11969396 says monomer 1boz PROBNOT 1 1 NPS NPS 9719595 9719595 -- Annotation transfered from 1s3u 1bp0 NO 2 2 C2 C2 10653645 10653645 SP says homodimer -- Annotation transfered from 4tms 1bp2 PROBNOT 1 1 NPS NPS 7265241 7265241 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1o2e 1bp4 PROBNOT 1 1 NPS NPS 9804696 9804696 Papain is a 23,400-dalton single polypeptide -- Annotation transfered from 9pap 1bp6 YES 2 2 NS C2 10653645 10653645 -- Annotation transfered from 1bpj 1bpi NO 1 1 NPS NPS 15299722 0 10731422 says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium - pH induced oligomerization -- Annotation transfered from 9pti 1bpj YES 2 2 NS C2 10653645 10653645 1bpm NO 6 6 D3 D3 8506345 8506345 Interface geometry conserved with 1gyt (30%) -- Annotation transfered from 1bll 1bpn NO 6 6 D3 D3 8506345 8506345 Interface geometry conserved with 1gyt (30%) -- Annotation transfered from 1bll 1bpo PROBYES 3 1 NS NPS 9827808 9827808 PAper says: Other proteins in addition to clathrin are required for assembly under physiological conditions - plus an identical prot is said to elute as a monomer. (10655490) 1bpq PROBYES 2 1 C2 NPS 1751497 1751497 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution 1bpt NO 1 1 NPS NPS 8518731 8518731 10731422 says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium - pH induced oligomerization -- Annotation transfered from 9pti 1bpw NO 4 4 D2 D2 9792097 9792097 Paper says tetramer -- Annotation transfered from 1a4s 1bq1 NO 2 2 C2 C2 9826509 9826509 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1bq2 NO 2 2 C2 C2 9826509 9826509 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1bq3 NO 4 4 D2 D2 10369755 10369755 11038361 and SP say tetramer -- Annotation transfered from 4pgm 1bq4 NO 4 4 D2 D2 10369755 10369755 11038361 and SP say tetramer -- Annotation transfered from 4pgm 1bq5 NO 3 3 C3 C3 9792907 9792907 Active site at the monomer-monomer interface -- Annotation transfered from 1oe3 1bq6 NO 2 2 C2 C2 10426957 10426957 -- Annotation transfered from 1d6f 1bq7 PROBYES 6 1 C2 NPS 10210188 10210188 It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown) 1bq8 PROBNOT 1 1 NPS NPS -1 0 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1iu5 1bq9 PROBNOT 1 1 NPS NPS -1 0 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1iu5 1bqa NO 2 2 C2 C2 9893985 9893985 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1bqd NO 2 2 C2 C2 9893985 9893985 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1bqe NO 1 1 NPS NPS 11152461 11152461 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1bqg NO 4 4 D2 D2 9772161 9772161 Paper says tetramer 1bqi PROBNOT 1 1 NPS NPS 9804696 9804696 Papain is a 23,400-dalton single polypeptide -- Annotation transfered from 9pap 1bqk NO 1 1 NPS NPS 10364229 0 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 -- Annotation transfered from 1zia 1bqo PROBYES 2 1 C2 NPS 9733482 9733482 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme -- Annotation transfered from 1hfs 1bqr NO 1 1 NPS NPS 10364229 0 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 -- Annotation transfered from 1zia 1bqu YES 2 1 NS NPS 9501088 9501088 Paper says: Crystallization trials yielded highly ordered crystals of 1pace group C2221 (unit cell dimensions a 84.5 Å, b s 32.3 Å, c 121.9 Å) which contained two gp130-CHR molecules per crystallographic asymmetric unit. The non-crystallographic symmetry does not reveal any possible mode of receptor dimerization. -- very interesting: gp130 is a repector that dimerizes upon IL binding and triggers downstream cascades. KO is lethal and many tissues do not form properly. -- protein induced dimerization 1bqy PROBYES 2 1 NS NPS 9753698 9753698 BU changed since last release and is now incorrect - Paper says nothing, PISA says monomer 1br5 PROBNOT 1 1 NPS NPS 9086280 9086280 Blocked ricin undergoes a pH-dependent reversible self-association, being predominantly dimeric at neutral pH and monomeric at acidic pH. -- Annotation transfered from 1apg 1br6 PROBNOT 1 1 NPS NPS 9086280 9086280 Blocked ricin undergoes a pH-dependent reversible self-association, being predominantly dimeric at neutral pH and monomeric at acidic pH. -- Annotation transfered from 1apg 1br8_1 PROBYES 1 2 NPS C2 9761669 15342247 BU changed since last release and is now incorrect - 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization - automaticaly inferred from 1jvq 1br8_2 PROBYES 1 2 NPS C2 9761669 15342247 BU changed since last release and is now incorrect - 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization - automaticaly inferred from 1jvq 1bra PROBYES 2 1 C2 NPS 8478942 8478942 Trysin is monomeric -- Annotation transfered from 1anb 1bre_1 YES 12 2 C2 C2 7568160 9990143 BU changed since last release and is now incorrect - - automaticaly inferred from 1qp1 1brf PROBNOT 1 1 NPS NPS -1 0 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1iu5 1brg_1 YES 1 3 NPS C3 8263918 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1brg_2 YES 1 3 NPS C3 8263918 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1brg_3 YES 1 3 NPS C3 8263918 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1brj_1 YES 1 3 NPS C3 8605178 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1brj_2 YES 1 3 NPS C3 8605178 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1brj_3 YES 1 3 NPS C3 8605178 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1brk_1 YES 1 3 NPS C3 8605178 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1brk_2 YES 1 3 NPS C3 8605178 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1brk_3 YES 1 3 NPS C3 8605178 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1brm_1 NO 2 2 C2 C2 10369777 15288787 - automatic transfer from 1t4b 1brm_2 NO 2 2 C2 C2 10369777 15288787 - automatic transfer from 1t4b 1brn_1 YES 1 3 NPS C3 8110767 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1brn_2 YES 1 3 NPS C3 8110767 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bro_1 NO 3 3 C3 C3 7664081 9642069 -- Interface geometry conserved with 1a88 - automatic transfer from 1brt 1bro_2 NO 3 3 C3 C3 7664081 9642069 -- Interface geometry conserved with 1a88 - automatic transfer from 1brt 1brp NO 1 1 NPS NPS 8464067 8464067 Serum retinol binding protein (RBP) is a monomeric protein of molecular weight 21,000 that transports vitamin A in the circulation -- Annotation transfered from 1jyd 1brq NO 1 1 NPS NPS 8464067 8464067 Serum retinol binding protein (RBP) is a monomeric protein of molecular weight 21,000 that transports vitamin A in the circulation -- Annotation transfered from 1jyd 1brr NO 3 3 C3 C3 9751724 9751724 SP says trimer -- Annotation transfered from 2brd 1brt NO 3 3 C3 C3 9642069 9642069 -- Interface geometry conserved with 1a88 1bru PROBNOT 1 1 NPS NPS 0 0 No paper but related structures are monomeric and PISA says monomer 1brx NO 3 3 C3 C3 9632391 9632391 SP says trimer -- Annotation transfered from 2brd 1bs0 YES 1 2 NPS C2 9813126 9813126 Paper describes a dimer and PISA finds it -- Annotation transfered from 1dje 1bs1 YES 1 2 NPS C2 9865950 9865950 Active form is a homodimer 1bs3 NO 4 4 D2 D2 10231372 10231372 The overall structure of the SOD remains a compact tetrameter and is comparable to that at pH 6.1 no matter whether the pH increases or fluoride is added -- Annotation transfered from 1bsm 1bs4_1 NO 1 1 NPS NPS 9846875 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bs4_2 NO 1 1 NPS NPS 9846875 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bs4_3 NO 1 1 NPS NPS 9846875 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bs5_1 NO 1 1 NPS NPS 9846875 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bs5_2 NO 1 1 NPS NPS 9846875 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bs5_3 NO 1 1 NPS NPS 9846875 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bs6_1 NO 1 1 NPS NPS 9846875 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bs6_2 NO 1 1 NPS NPS 9846875 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bs6_3 NO 1 1 NPS NPS 9846875 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bs7_1 NO 1 1 NPS NPS 9565550 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bs7_2 NO 1 1 NPS NPS 9565550 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bs7_3 NO 1 1 NPS NPS 9565550 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bs8_1 NO 1 1 NPS NPS 9846875 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bs8_2 NO 1 1 NPS NPS 9846875 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bs8_3 NO 1 1 NPS NPS 9846875 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bsa_1 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bsa_2 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bsa_3 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bsb_1 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bsb_2 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bsb_3 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bsc_1 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bsc_2 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bsc_3 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bsd_1 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bsd_2 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bsd_3 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bse_1 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bse_2 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bse_3 YES 1 3 NPS C3 8254677 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 1bsf NO 2 2 C2 C2 9778348 9778348 1bsg PROBNOT 1 1 NPS NPS 3499147 3499147 Paper says nothing, related proteins are monomeric and PISA says monomer 1bsj NO 1 1 NPS NPS 10200158 10200158 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues -- Annotation transfered from 1dff 1bsk NO 1 1 NPS NPS 10200158 10200158 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues -- Annotation transfered from 1dff 1bsl NO 2 2 C2 C2 9007973 9007973 Paper says: Luciferase, as isolated from Vibrio harveyi, is an alpha beta heterodimer. When allowed to fold in the absence of the alpha subunit, either in vitro or in vivo, the beta subunit of enzyme will form a kinetically stable homodimer that does not unfold even after prolonged incubation in 5 M urea at pH 7.0 and 18 degrees C. 1bsm NO 4 4 D2 D2 10231372 10231372 The overall structure of the SOD remains a compact tetrameter and is comparable to that at pH 6.1 no matter whether the pH increases or fluoride is added 1bso PROBNOT 2 2 C2 C2 9827560 9827560 SP says: Under physiological conditions beta-lactoglobulin exists as an equilibrium mixture of monomeric and dimeric forms -- Annotation transfered from 2blg 1bsp NO 2 2 C2 C2 9778348 9778348 -- Annotation transfered from 1bsf 1bsq PROBNOT 1 1 NPS NPS 10210185 10210185 SP says: Under physiological conditions beta-lactoglobulin exists as an equilibrium mixture of monomeric and dimeric forms -- Annotation transfered from 1gxa 1bsr NO 2 2 C2 C2 15299514 0 -- Annotation transfered from 11ba 1bsv NO 2 2 C2 C2 9862812 9862812 SP and paper say dimer -- Annotation transfered from 1e7s 1bsx PROBYES 2 1 NS NPS 9808622 9808622 BU changed since last release and is now incorrect - Others are monomers, paper says nothing and PISA says monomer. 1bsy PROBNOT 2 2 C2 C2 9760236 9760236 SP says: Under physiological conditions beta-lactoglobulin exists as an equilibrium mixture of monomeric and dimeric forms -- Annotation transfered from 2blg 1bsz_1 NO 1 1 NPS NPS 9846875 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bsz_2 NO 1 1 NPS NPS 9846875 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bsz_3 NO 1 1 NPS NPS 9846875 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1bt4 NO 2 2 C2 C2 0 0 1bt5 PROBNOT 1 1 NPS NPS -1 0 EcoCyc says monomer -- Annotation transfered from 1jwp 1bt6 YES 2 4 C2 C2 9886297 9886297 Paper says dimer that further forms a tetramer via disulfide bridges 1bt8 NO 4 4 D2 D2 10231372 10231372 The overall structure of the SOD remains a compact tetrameter and is comparable to that at pH 6.1 no matter whether the pH increases or fluoride is added -- Annotation transfered from 1bsm 1bt9 NO 3 3 C3 C3 9843370 9843370 Interface geometry conserved with 1prn (20%) -- Annotation transfered from 1gfn 1btc PROBNOT 1 1 NPS NPS 1491009 1491009 SP says monomer -- Annotation transfered from 1v3i 1btg PROBYES 3 2 NS C2 8201620 8201620 SP says dimer 1bti NO 1 1 NPS NPS 8518731 8518731 10731422 says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium - pH induced oligomerization -- Annotation transfered from 9pti 1btl PROBNOT 1 1 NPS NPS 8356032 0 EcoCyc says monomer -- Annotation transfered from 1jwp 1btm NO 2 2 C2 C2 8580851 8580851 Interface geometry conserved with 1m6j (43%) - paper says dimer -- Annotation transfered from 2btm 1bto_1 PROBNOT 2 2 C2 C2 9003191 9132002 BU changed since last release and is now corrected - - automaticaly inferred from 1lde 1bto_2 PROBNOT 2 2 C2 C2 9003191 9132002 BU changed since last release and is now corrected - - automaticaly inferred from 1lde 1btp PROBNOT 1 1 NPS NPS 7548040 7548040 -- Annotation transfered from 1az8 1btu PROBNOT 1 1 NPS NPS 9860865 9860865 -- Annotation transfered from 1c1m 1btw PROBNOT 1 1 NPS NPS 7599119 7599119 -- Annotation transfered from 1az8 1btx PROBNOT 1 1 NPS NPS 7599119 7599119 -- Annotation transfered from 1az8 1bty PROBNOT 1 1 NPS NPS 7599119 7599119 -- Annotation transfered from 1az8 1btz PROBNOT 1 1 NPS NPS 7599119 7599119 -- Annotation transfered from 1az8 1bu1 PROBYES 6 1 NS NPS 9778343 9778343 1bu3 PROBNOT 2 2 C2 C2 9385642 9385642 the EF fragment exists in a monomer-dimer equilibrium when complexed with La3+ 1bu5 PROBYES 2 1 NS NPS 9874201 9874201 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins 1bu6 NO 4 4 D2 D2 9817843 9817843 The enzyme exists in solution as functional dimers that associate reversibly to form tetramers - Dimer tetramer equilibrium 1bu7_1 NA 1 1 NPS NPS 10051560 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1bu7_2 NA 1 1 NPS NPS 10051560 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1bue PROBNOT 1 1 NPS NPS 9756914 9756914 Paper: http://pubs.acs.org/cgi-bin/article.cgi/jacsat/1998/120/i36/html/ja9817996.html Says nothing PISA says monomer -- Annotation transfered from 1bul 1bul PROBNOT 1 1 NPS NPS -1 0 Paper: http://pubs.acs.org/cgi-bin/article.cgi/jacsat/1998/120/i36/html/ja9817996.html Says nothing PISA says monomer 1buo PROBNOT 2 2 C2 C2 9770450 10537309 BU changed since last release and is now corrected - There is a very large interface! (>30 residues) - automaticaly inferred from 1cs3 1bux NO 6 6 D3 D3 9786875 9786875 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1bv1 PROBNOT 2 2 C2 C2 8946858 16272319 Abs detected, besides a Bet v 1 monomer of 17 kDa, a dimer of 34 kDa. In dynamic light scattering, Bet v 1 appeared as dimers and even multimers, but a single condition could be defined where it behaved exclusively monomerically - monomer dimer equilibrium - interesting 1bv3 PROBNOT 1 1 NPS NPS 10550681 10550681 9000633 says monomeric -- Annotation transfered from 1uga 1bv4 YES 4 2 C2 C2 9922165 9922165 1bv7 NO 2 2 C2 C2 9790666 9790666 -- Annotation transfered from 1ajx 1bv9 NO 2 2 C2 C2 9790666 9790666 -- Annotation transfered from 1ajx 1bva PROBNOT 1 1 NPS NPS 9836578 9836578 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1bvb PROBNOT 1 1 NPS NPS 9808046 9808046 Paper says nothing, PISA says monomer and family mostly monomeric 1bvc NO 1 1 NPS NPS 7707378 7707378 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1bvd NO 1 1 NPS NPS 7707378 7707378 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1bvq NO 4 4 D2 D2 9837940 9837940 PID 9837940 On the basis of gel filtration experiments, the thioesterase from Pseudomonas sp. strain CBS was shown to be a homotetramer -- Annotation transfered from 1lo7 1bvr_1 YES 2 4 C2 D2 10336454 7886450 - automatic transfer from 1eny 1bvr_2 PROBNOT 4 4 D2 D2 10336454 7886450 BU changed since last release and is now corrected - - automaticaly inferred from 1eny 1bvs NO 8 8 D4 D4 9774974 9774974 Paper says octamer 1bvt NO 1 1 NPS NPS 9761898 9730812 1bvv PROBNOT 1 1 NPS NPS 10220321 10220321 Paper says nothing and PISA says monomer -- Annotation transfered from 1xnb 1bvw PROBNOT 1 1 NPS NPS 9882628 9882628 Paper says nothing, PISA says monomer -- Annotation transfered from 1oc6 1bvx NO 1 1 NPS NPS 10089304 10089304 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1bwa NO 2 2 C2 C2 9790666 9790666 -- Annotation transfered from 1ajx 1bwb NO 2 2 C2 C2 9790666 9790666 -- Annotation transfered from 1ajx 1bwc NO 2 2 C2 C2 9986706 9986706 Paper says dimer -- Annotation transfered from 5grt 1bwd YES 2 2 NS C2 9922132 9922132 BU changed since last release and is now incorrect - Interface geometry conserved with 2jdw (38%) 1bwf NO 2 2 C2 C2 10090737 10090737 Mutation introduced to prevent tetramer formation - Escherichia coli glycerol kinase (GK) displays half-of-the-sites reactivity toward ATP and allosteric regulation by fructose 1, 6-bisphosphate (FBP), which has been shown to promote dimer-tetramer assembly and to inhibit only tetramers. To probe the role of tetramer assembly, a mutation (Ser58-->Trp) was designed to sterically block formation of the dimer-dimer interface near the FBP binding site [Ormo, M., Bystrom, C., and Remington, S. J. (1998) Biochemistry 37, 16565-16572]. The substitution did not substantially change the Michaelis constants or alter allosteric regulation of GK by a second effector, the phosphocarrier protein IIAGlc; however, it eliminated FBP inhibition. - - interesting to show that in some cases we have no clue what QS is useful for. -- Annotation transfered from 1glj 1bwh NO 1 1 NPS NPS 10089304 10089304 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1bwi NO 1 1 NPS NPS 10089304 10089304 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1bwj NO 1 1 NPS NPS 10089304 10089304 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1bwk PROBYES 1 2 NPS C2 9830019 9830019 Paper says dimer -- Annotation transfered from 1bwl 1bwl PROBYES 1 2 NPS C2 9830019 9830019 Paper says dimer 1bwo PROBYES 2 1 NS NPS 10491104 10491104 BU changed since last release and is now incorrect - Gel filt. performed but no dimer reported. 1bws YES 2 2 NS C2 9817848 9817848 -- Annotation transfered from 1fxs 1bww NO 2 2 C2 C2 10329778 10329778 Paper says dimer -- Annotation transfered from 1ar2 1bx0 PROBNOT 1 1 NPS NPS 9852055 9852055 -- Annotation transfered from 1fnb 1bx1 PROBNOT 1 1 NPS NPS 9852055 9852055 -- Annotation transfered from 1fnb 1bx3 NO 2 2 C2 C2 10211820 10211820 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1bx6 NO 1 1 NPS NPS 10029530 10029530 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1bx9 NO 2 2 C2 C2 9817846 9817846 1bxa NO 1 1 NPS NPS 9860825 9860825 Amicyanin is a monomeric protein with a molecular weight of 15000 (Husain & Davidson, 1985) -- Annotation transfered from 1aaj 1bxe PROBNOT 1 1 NPS NPS 9862810 9862810 Paper implies it is a monomer and PISA agrees 1bxh NO 4 4 D2 D2 10336986 10336986 SP says tetramer -- Annotation transfered from 1cjp 1bxk PROBNOT 2 2 C2 C2 0 0 Paper not found but similar structus are dimers and PISasays dimer 1bxm PROBYES 2 1 C2 NPS 10386869 10386869 Out of the three almost identical proteins, no paper mentions a dimer, PISA says dimer for one only so Ill say monomer for all of them. 1bxo NO 1 1 NPS NPS 9836576 9836576 1bxq NO 1 1 NPS NPS 9836576 9836576 -- Annotation transfered from 1bxo 1bxr PROBNOT 8 8 D2 D2 10029528 11551199 Carbamoyl phosphate synthetase (CPS) from Escherichia coli is allosterically regulated by the metabolites ornithine, IMP, and UMP. Ornithine and IMP function as activators, whereas UMP is an inhibitor. CPS undergoes changes in the state of oligomerization that are dependent on the protein concentration and the binding of allosteric effectors. Ornithine and IMP promote the formation of an (ab)4 tetramer while UMP favors the formation of an (ab)2 dimer. Propagate to all (CPS) please! -) 1bxs NO 4 4 D2 D2 9862807 9862807 Interface geometry conserved with 1uxr (32%) 1bxt PROBYES 2 1 NS NPS 10048922 10048922 1bxu PROBNOT 1 1 NPS NPS 10320332 10320332 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) -- Annotation transfered from 1bxv 1bxv PROBNOT 1 1 NPS NPS 10320332 10320332 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) 1bxz NO 4 4 D2 D2 10651277 10651277 1by7 PROBNOT 1 1 NPS NPS 10368272 10368272 Paper says nothing, PISA says monomer -- Annotation transfered from 1jrr 1by8 NO 1 1 NPS NPS 9893980 9893980 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa -- Annotation transfered from 1atk 1bya PROBNOT 1 1 NPS NPS 8011643 8011643 SP says monomer -- Annotation transfered from 1v3i 1byb PROBNOT 1 1 NPS NPS 8011643 8011643 SP says monomer -- Annotation transfered from 1v3i 1byc PROBNOT 1 1 NPS NPS 8011643 8011643 SP says monomer -- Annotation transfered from 1v3i 1byd PROBNOT 1 1 NPS NPS 8011643 8011643 SP says monomer -- Annotation transfered from 1v3i 1bye_1 NO 2 2 C2 C2 9817846 9417926 - automatic transfer from 1axd 1bye_2 NO 2 2 C2 C2 9817846 9417926 - automatic transfer from 1axd 1byf NO 2 2 C2 C2 10398588 10398588 Analytical ultracentrifugation revealed that TC14 behaves as a dimer in solution. -- Annotation transfered from 1tlg 1byg PROBNOT 1 1 NPS NPS 9878439 9878439 Paper says nothing, PISA says monomer 1byi NO 2 2 C2 C2 10089457 10089457 Active form is a homodimer -- Annotation transfered from 1a82 1byk NO 2 2 C2 C2 9865945 9148912 Said to be a homodimer in that paper. EcoCyc would be wrong? 1byo_1 PROBNOT 1 1 NPS NPS 10220581 10220581 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) - automatic transfer from 1byp 1byo_2 PROBNOT 1 1 NPS NPS 10220581 10220581 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) - automatic transfer from 1byp 1byp PROBNOT 1 1 NPS NPS 10220581 10220581 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) 1byq NA 1 1 NPS NPS 9817749 9817749 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization -- Annotation transfered from 1uy6 1byu NO 2 2 C2 C2 9878368 9878368 Paper says dimer 1bz5 NO 10 10 D5 D5 10731422 10731422 paper says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium 1bz6 NO 1 1 NPS NPS 10205052 10205052 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1bz8 NO 4 4 D2 D2 0 0 transthyretin is tetrameric -- Annotation transfered from 1fh2 1bza PROBNOT 1 1 NPS NPS 9925786 9925786 SP says monomer -- Annotation transfered from 1iyo 1bzc PROBNOT 1 1 NPS NPS 9922143 9922143 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1bzd NO 4 4 D2 D2 9818054 9818054 transthyretin is tetrameric -- Annotation transfered from 1fh2 1bze NO 4 4 D2 D2 9818054 9818054 transthyretin is tetrameric -- Annotation transfered from 1fh2 1bzh PROBNOT 1 1 NPS NPS 9922143 9922143 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1bzj PROBNOT 1 1 NPS NPS 9922143 9922143 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1bzl NO 2 2 C2 C2 10368274 10368274 Large interface and closely related dimer 1bzm NO 1 1 NPS NPS 7932756 7932756 10529183 says monomer -- Annotation transfered from 1crm 1bzo YES 2 2 C2 C2 9878406 9878406 Wrong interface of the dimer 1bzp NO 1 1 NPS NPS 10205052 10205052 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1bzr NO 1 1 NPS NPS 10205052 10205052 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1bzs PROBNOT 1 1 NPS NPS 10354399 10354399 No clear evidence after a quick search but PISA agrees ... -- Annotation transfered from 1a85 1bzw NO 4 4 C2 C2 -1 0 Paper says tetramer -- Annotation transfered from 2pel 1bzy NO 4 4 D2 D2 10360366 10360366 Tetramer, interface conserved down to 40% (1fsg). 1c02 NA 2 1 C2 NPS 10543964 10543964 The site where the homodimer forms is the same as that use for hetero-dimerization. No information has been found in the paper. 1c09 PROBYES 3 1 NS NPS 10555962 10555962 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes 1c0a YES 1 2 NPS C2 10562565 10562565 BU changed since last release and is now incorrect - Interface geometry conserved with 1g51 (48%) 1c0b NO 1 1 NPS NPS 10548049 10548049 -- Annotation transfered from 6rsa 1c0c NO 1 1 NPS NPS 10548049 10548049 -- Annotation transfered from 6rsa 1c0n NO 2 2 C2 C2 10684605 10684605 -- Annotation transfered from 1i29 1c0w YES 4 4 C2 NA 10497029 10497029 BU changed since last release and is now incorrect - Two dimers bind a piece of DNA 1c10 NO 1 1 NPS NPS 9443341 9443341 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1c14 NO 4 4 D2 D2 10595560 10595560 1c1f NO 2 2 C2 C2 10545323 10545323 Paper says dimer 1c1j_1 PROBNOT 2 2 C2 C2 -1 9761847 BU changed since last release and is now corrected - Paper says dimer - automaticaly inferred from 1b4w 1c1j_2 PROBNOT 2 2 C2 C2 -1 9761847 BU changed since last release and is now corrected - Paper says dimer - automaticaly inferred from 1b4w 1c1l NO 2 2 C2 C2 10545323 10545323 Paper says dimer -- Annotation transfered from 1c1f 1c1m PROBNOT 1 1 NPS NPS 9443341 9443341 1c1n PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1c1o PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1c1p PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1c1q PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1c1r PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1c1s PROBNOT 1 1 NPS NPS 10497030 9468142 -- Annotation transfered from 1az8 1c1t PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1c28 NO 3 3 C3 C3 9512423 9512423 Interface geometry conserved with 1gr3 (47%) 1c29 NO 4 4 C2 C2 10504236 10504236 Paper says a2b2 -- Annotation transfered from 2wsy 1c2b PROBNOT 4 4 D2 D2 10521413 10521413 The paper suggests this tetramer is relevant 1c2d PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1c2e PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1c2f PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1c2g PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1c2h PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1c2i PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1c2j PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1c2k PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1c2l PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1c2m PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1c2o PROBNOT 4 4 C2 C2 10521413 10521413 The paper suggests this tetramer is relevant but I am not sure about that. 1c2p PROBYES 2 1 C2 NPS 10504728 10504728 HCV RdRp exists primarily as a monomer -- Annotation transfered from 1csj 1c2t PROBYES 2 1 C2 NPS 10606510 10606510 9698564 says: E. coli GarTfase exhibits a pH-dependent monomer-dimer equilibrium with the monomer preferably populated above pH 7.4 and the dimer below pH 6.6 -- pH induced dimerization -- this interface is too weak 1c30 PROBNOT 8 8 D2 D2 10587438 11551199 Carbamoyl phosphate synthetase (CPS) from Escherichia coli is allosterically regulated by the metabolites ornithine, IMP, and UMP. Ornithine and IMP function as activators, whereas UMP is an inhibitor. CPS undergoes changes in the state of oligomerization that are dependent on the protein concentration and the binding of allosteric effectors. Ornithine and IMP promote the formation of an (ab)4 tetramer while UMP favors the formation of an (ab)2 dimer. Propagate to all (CPS) please! -) -- Annotation transfered from 1bxr 1c3b PROBYES 2 1 C2 NPS 10595535 10595535 AmpC is a class C beta Lactamase and those are monomeric (12951239) 1c3c NO 4 4 D2 D2 10673438 10673438 Interface geometry conserved with 1fur (29%) 1c3d NO 1 1 NPS NPS 9596584 9596584 paper 10825534 implies it is a monomer 1c3e PROBYES 2 1 C2 NPS 10606510 10606510 9698564 says: E. coli GarTfase exhibits a pH-dependent monomer-dimer equilibrium with the monomer preferably populated above pH 7.4 and the dimer below pH 6.6 -- pH induced dimerization -- this interface is too weak 1c3f PROBNOT 1 1 NPS NPS 10595536 10595536 1c3g NA 2 2 NS C2 10997899 10329795 Paper says: The apparent molecular weight of Sis1 is shown to be [sim]80 kDa from the elution time of the protein peak, indicating that Sis1 may form a dimer in solution. -- however, PISA finds another dimer 1c3h_1 NO 3 3 C3 C3 0 9512423 Interface geometry conserved with 1gr3 (47%) - automatic transfer from 1c28 1c3h_2 NO 3 3 C3 C3 0 9512423 Interface geometry conserved with 1gr3 (47%) - automatic transfer from 1c28 1c3i PROBYES 2 1 C2 NPS 10877850 10877850 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme -- Annotation transfered from 1hfs 1c3j PROBNOT 1 1 NPS NPS 10497034 10497034 SP says monomer -- Annotation transfered from 1bgt 1c3k NA 4 4 C2 C2 10647178 10647178 Forms an octameric ring in the crystal that is presumably more stable than half of the ring. However, the paper says that they do not observe an octamer, but a tetramer. 1c3l NO 1 1 NPS NPS 9443341 9443341 -- Annotation transfered from 1be6 1c3m NA 4 4 C2 C2 10647178 10647178 Forms an octameric ring in the crystal that is presumably more stable than half of the ring. However, the paper says that they do not observe an octamer, but a tetramer. -- Annotation transfered from 1c3k 1c3n NA 4 4 C2 C2 10647178 10647178 Forms an octameric ring in the crystal that is presumably more stable than half of the ring. However, the paper says that they do not observe an octamer, but a tetramer. -- Annotation transfered from 1c3k 1c3o PROBNOT 8 8 D2 D2 10587438 11551199 Carbamoyl phosphate synthetase (CPS) from Escherichia coli is allosterically regulated by the metabolites ornithine, IMP, and UMP. Ornithine and IMP function as activators, whereas UMP is an inhibitor. CPS undergoes changes in the state of oligomerization that are dependent on the protein concentration and the binding of allosteric effectors. Ornithine and IMP promote the formation of an (ab)4 tetramer while UMP favors the formation of an (ab)2 dimer. Propagate to all (CPS) please! -) -- Annotation transfered from 1bxr 1c3p PROBNOT 1 1 NPS NPS 10490031 10490031 -- Annotation transfered from 1c3s 1c3q NO 3 3 C3 C3 10891066 10891066 Interface geometry conserved with 1v8a (43%) -- Annotation transfered from 1esq 1c3r PROBYES 2 1 C2 NPS 10490031 10490031 the protein is functional as a monomer and they say in the paper that two important residues involved at the interface are not conserved 1c3s PROBNOT 1 1 NPS NPS 10490031 10490031 1c3u NO 4 4 D2 D2 10673438 10673438 Interface geometry conserved with 1fur (29%) -- Annotation transfered from 1c3c 1c3w NO 3 3 C3 C3 10452895 10452895 SP says trimer -- Annotation transfered from 2brd 1c3x NO 3 3 C3 C3 10600382 10600382 Interface conserved with 1v48 (36%) 1c43 NO 1 1 NPS NPS 10561612 10561612 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1c45 NO 1 1 NPS NPS 10561612 10561612 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1c46 NO 1 1 NPS NPS 10561612 10561612 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1c4f NO 1 1 NPS NPS 10220315 10220315 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1c4k YES 2 2 NS C2 10666573 10666573 Clear dimer 1c4t NO 3 3 C3 C3 10739245 10739245 Paper says: E2o is normally a 24-mer, but is found as a trimer when E2o is expressed with a C-terminal [His]6 tag. 1c4w NO 1 1 NPS NPS 10819997 10819997 CheY is a Mr 14,000 monomeric protein -- Annotation transfered from 1chn 1c4x YES 8 1 D4 NPS -1 0 BU changed since last release and is now incorrect - Paper not found - no info so rely on structure PISA who says monomer, seems likely but not sure. 1c50 NO 2 2 C2 C2 10873856 10873856 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1c52 NO 1 1 NPS NPS 9281430 9281430 -- Annotation transfered from 1dt1 1c5f_1 PROBNOT 1 1 NPS NPS 10642184 9655334 Paper says nothing - fragment - PISA says monomer - automatic transfer from 1a33 1c5f_2 PROBNOT 1 1 NPS NPS 10642184 9655334 Paper says nothing - fragment - PISA says monomer - automatic transfer from 1a33 1c5f_3 PROBNOT 1 1 NPS NPS 10642184 9655334 Paper says nothing - fragment - PISA says monomer - automatic transfer from 1a33 1c5f_4 PROBNOT 1 1 NPS NPS 10642184 9655334 Paper says nothing - fragment - PISA says monomer - automatic transfer from 1a33 1c5f_5 PROBNOT 1 1 NPS NPS 10642184 9655334 Paper says nothing - fragment - PISA says monomer - automatic transfer from 1a33 1c5f_6 PROBNOT 1 1 NPS NPS 10642184 9655334 Paper says nothing - fragment - PISA says monomer - automatic transfer from 1a33 1c5f_7 PROBNOT 1 1 NPS NPS 10642184 9655334 Paper says nothing - fragment - PISA says monomer - automatic transfer from 1a33 1c5f_8 PROBNOT 1 1 NPS NPS 10642184 9655334 Paper says nothing - fragment - PISA says monomer - automatic transfer from 1a33 1c5g PROBNOT 1 1 NPS NPS 7664104 7664104 Paper says nothing - Family mostly monomeric - PISA says monomer -- Annotation transfered from 1dvn 1c5h PROBNOT 1 1 NPS NPS 10860737 0 Paper says nothing and PISA says monomer -- Annotation transfered from 1xnb 1c5i PROBNOT 1 1 NPS NPS 10860737 10860737 Paper says nothing and PISA says monomer -- Annotation transfered from 1xnb 1c5m PROBNOT 2 2 NPS NPS 10779411 10779411 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1c5p PROBNOT 1 1 NPS NPS 10779411 10779411 -- Annotation transfered from 1az8 1c5q PROBNOT 1 1 NPS NPS 10779411 10779411 -- Annotation transfered from 1az8 1c5r PROBNOT 1 1 NPS NPS 10779411 10779411 -- Annotation transfered from 1az8 1c5s PROBNOT 1 1 NPS NPS 10779411 10779411 -- Annotation transfered from 1az8 1c5t PROBNOT 1 1 NPS NPS 10779411 10779411 -- Annotation transfered from 1az8 1c5u PROBNOT 1 1 NPS NPS 10779411 10779411 -- Annotation transfered from 1az8 1c5v PROBNOT 1 1 NPS NPS 10779411 10779411 -- Annotation transfered from 1az8 1c60 NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c61 NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c62 NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c63 NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c64 NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c65 NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c66 NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c67 NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c68 NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c69 NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6a NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6b NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6c NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6d NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6e NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6f NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6g NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6h NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6i NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6j NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6k NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6l NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6m NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6n NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6o NO 2 2 C2 C2 10438600 10438600 Under physiological ion concentrations (<10 mM) and protein concentrations (>20 mg/ml) cyt c6 was found to be a dimer in the reduced and in the oxidized state, whereas upon increasing ion and decreasing protein concentrations the dynamic equilibrium shifted towards the monomeric form. - monomer dimer equilibrium - Interface geometry conserved with 1cc5 and 1gdv (30%) 1c6p NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6q NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6r NO 1 1 NPS NPS 10438600 10438600 Reduced cytochrome c6crystallized as a monomer in the space group P 21212, whereas the oxidized protein crystallized as a dimer in the space group P 3121. 1c6t NO 1 1 NPS NPS 10993735 10993735 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1c6x NO 2 2 C2 C2 10739910 10739910 -- Annotation transfered from 1ajx 1c6y NO 2 2 C2 C2 10739910 10739910 -- Annotation transfered from 1ajx 1c6z NO 2 2 C2 C2 10739910 10739910 -- Annotation transfered from 1ajx 1c70 NO 2 2 C2 C2 10739910 10739910 -- Annotation transfered from 1ajx 1c72_1 NO 2 2 C2 C2 10903867 9571047 - automatic transfer from 1gsu 1c72_2 NO 2 2 C2 C2 10903867 9571047 - automatic transfer from 1gsu 1c74 PROBNOT 1 1 NPS NPS 11015210 11015210 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1o2e 1c75 PROBNOT 1 1 NPS NPS 11052663 11052663 PAper says nothing, PISA says monomer 1c76 YES 2 2 NS C2 0 0 The SAK dimer was detected by SDS/PAGE (15%), gel-filtration chromatography and MALDI-TOF mass spectroscopy. Gel-filtration analysis was carried out using a Superdex75 column (HR, 10/30, Amersham Pharmacia Biotech), eluting with 25 mm Tris/HCl, pH 8.0, 1 mm phenylmethanesulfonyl fluoride, 150 mm NaCl. The peak fractions were collected and analyzed by SDS/PAGE. The MALDI-TOF spectrum was obtained in positive ion mode with a Bruker BIFLEX III MALDI-TOF mass spectrometer using α-cyano-4-hydroxycinnamicbacid (CCA) as the matrix. -- however, they show an isologous interaction in the paper -- Annotation transfered from 1c77 1c77 YES 2 2 NS C2 11856331 11856331 The SAK dimer was detected by SDS/PAGE (15%), gel-filtration chromatography and MALDI-TOF mass spectroscopy. Gel-filtration analysis was carried out using a Superdex75 column (HR, 10/30, Amersham Pharmacia Biotech), eluting with 25 mm Tris/HCl, pH 8.0, 1 mm phenylmethanesulfonyl fluoride, 150 mm NaCl. The peak fractions were collected and analyzed by SDS/PAGE. The MALDI-TOF spectrum was obtained in positive ion mode with a Bruker BIFLEX III MALDI-TOF mass spectrometer using α-cyano-4-hydroxycinnamicbacid (CCA) as the matrix. -- however, they show an isologous interaction in the paper 1c78 PROBNOT 2 2 C2 C2 11856331 11856331 BU changed since last release and is now corrected - The SAK dimer was detected by SDS/PAGE (15%), gel-filtration chromatography and MALDI-TOF mass spectroscopy. Gel-filtration analysis was carried out using a Superdex75 column (HR, 10/30, Amersham Pharmacia Biotech), eluting with 25 mm Tris/HCl, pH 8.0, 1 mm phenylmethanesulfonyl fluoride, 150 mm NaCl. The peak fractions were collected and analyzed by SDS/PAGE. The MALDI-TOF spectrum was obtained in positive ion mode with a Bruker BIFLEX III MALDI-TOF mass spectrometer using α-cyano-4-hydroxycinnamicbacid (CCA) as the matrix. -- however, they show an isologous interaction in the paper - automaticaly inferred from 1c77 1c79 PROBNOT 2 2 C2 C2 11856331 11856331 BU changed since last release and is now corrected - The SAK dimer was detected by SDS/PAGE (15%), gel-filtration chromatography and MALDI-TOF mass spectroscopy. Gel-filtration analysis was carried out using a Superdex75 column (HR, 10/30, Amersham Pharmacia Biotech), eluting with 25 mm Tris/HCl, pH 8.0, 1 mm phenylmethanesulfonyl fluoride, 150 mm NaCl. The peak fractions were collected and analyzed by SDS/PAGE. The MALDI-TOF spectrum was obtained in positive ion mode with a Bruker BIFLEX III MALDI-TOF mass spectrometer using α-cyano-4-hydroxycinnamicbacid (CCA) as the matrix. -- however, they show an isologous interaction in the paper - automaticaly inferred from 1c77 1c7e_1 PROBNOT 1 1 NPS NPS 12206666 11264581 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins - automatic transfer from 1f4p 1c7e_2 PROBNOT 1 1 NPS NPS 12206666 11264581 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins - automatic transfer from 1f4p 1c7f_1 PROBNOT 1 1 NPS NPS 12206666 11264581 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins - automatic transfer from 1f4p 1c7f_2 PROBNOT 1 1 NPS NPS 12206666 11264581 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins - automatic transfer from 1f4p 1c7h NO 2 2 C2 C2 10529226 10529226 -- Annotation transfered from 1e3v 1c7i PROBNOT 1 1 NPS NPS 10535917 10535917 SP says monomer -- Annotation transfered from 1c7j 1c7j PROBNOT 1 1 NPS NPS 10535917 10535917 SP says monomer 1c7p NO 1 1 NPS NPS 10810162 10810162 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1c7s PROBYES 2 1 C2 NPS 10884356 10884356 SP and PISA say monomer 1c7t PROBYES 2 1 C2 NPS 10884356 10884356 SP and PISA say monomer -- Annotation transfered from 1c7s 1c7y NO 4 4 C4 C4 10890893 10890893 BU changed since last release and is now corrected - -- DNA repeated 16 times 1c7z PROBNOT 2 2 C2 C2 0 0 Paper says: the bisphosphatase dimerizes at high protein concentrations. We believe that the two subunits found in the crystallographic asymmetric unit may represent the dimeric form of the bisphosphatase domain and perhaps the interface contained in the bifunctional enzyme. -- Annotation transfered from 1fbt 1c80 PROBNOT 2 2 C2 C2 0 0 Paper says: the bisphosphatase dimerizes at high protein concentrations. We believe that the two subunits found in the crystallographic asymmetric unit may represent the dimeric form of the bisphosphatase domain and perhaps the interface contained in the bifunctional enzyme. -- Annotation transfered from 1fbt 1c81 PROBYES 2 2 NS C2 0 0 8634242 says: the bisphosphatase dimerizes at high protein concentrations. We believe that the two subunits found in the crystallographic asymmetric unit may represent the dimeric form of the bisphosphatase domain and perhaps the interface contained in the bifunctional enzyme. 1c83 PROBNOT 1 1 NPS NPS 10702277 10702277 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1c84 PROBNOT 1 1 NPS NPS 10702277 10702277 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1c85 PROBNOT 1 1 NPS NPS 10702277 10702277 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1c86 PROBNOT 1 1 NPS NPS 10744717 10744717 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1c87 PROBNOT 1 1 NPS NPS 10744717 10744717 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1c88 PROBNOT 1 1 NPS NPS 10744717 10744717 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1c8i PROBNOT 1 1 NPS NPS 10915789 10915789 Peroxidases seem to be monomeric in general -- Annotation transfered from 1gza 1c8j_1 PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1c8j_2 PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1c8k NO 2 2 C2 C2 10924512 10924512 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1c8l NO 2 2 C2 C2 11368311 11368311 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1c8r YES 1 3 NPS C3 10514362 10514362 SP says trimer 1c8s NO 3 3 C3 C3 10514362 10514362 Interface geometry conserved with 1e12 (31%) 1c8t PROBYES 2 1 C2 NPS 10877850 10877850 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme -- Annotation transfered from 1hfs 1c8v NO 4 4 C2 C2 10504236 10504236 Paper says a2b2 -- Annotation transfered from 2wsy 1c8w NO 1 1 NPS NPS 11087402 11087402 -- Annotation transfered from 6rsa 1c8x PROBNOT 1 1 NPS NPS 10595536 10595536 -- Annotation transfered from 1c3f 1c8y PROBNOT 1 1 NPS NPS 10595536 10595536 -- Annotation transfered from 1c3f 1c90_1 PROBNOT 1 1 NPS NPS 10595536 10595536 - automatic transfer from 1c3f 1c90_2 PROBNOT 1 1 NPS NPS 10595536 10595536 - automatic transfer from 1c3f 1c91 PROBNOT 1 1 NPS NPS 10595536 10595536 -- Annotation transfered from 1c3f 1c92 PROBNOT 1 1 NPS NPS 10595536 10595536 -- Annotation transfered from 1c3f 1c93 PROBNOT 1 1 NPS NPS 10595536 10595536 -- Annotation transfered from 1c3f 1c9c NO 2 2 C2 C2 10858450 10858450 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1c9d NO 4 4 C2 C2 10504236 10504236 Paper says a2b2 -- Annotation transfered from 2wsy 1c9h PROBNOT 1 1 NPS NPS 10713512 10713512 FKBP12.6 is a novel isoform of FKBP12 and FKBP12 is a monomer so Id say it is too (plus it has a F at position 36, cf annotation of 2fke) 1c9i PROBYES 2 1 NS NPS 10655490 10655490 Paper says: The fractions containing the terminal domain were collected, concentrated, and loaded on a Superdex 75 column for size-exclusion chromatography in buffer A. The td40 eluted as a monomeric species 1c9j NO 1 1 NPS NPS 10493860 10493860 -- Annotation transfered from 1c9n 1c9l PROBYES 2 1 NS NPS 10655490 10655490 Paper says: The fractions containing the terminal domain were collected, concentrated, and loaded on a Superdex 75 column for size-exclusion chromatography in buffer A. The td40 eluted as a monomeric species -- Annotation transfered from 1c9i 1c9m NO 1 1 NPS NPS 10493860 10493860 -- Annotation transfered from 1c9n 1c9n NO 1 1 NPS NPS 10493860 10493860 1c9o PROBYES 2 1 C2 NPS 10736231 10736231 Monomeric in most conditions (9501917) -- Annotation transfered from 1hzc 1c9v NO 1 1 NPS NPS 11305910 11305910 -- Annotation transfered from 6rsa 1c9w PROBNOT 1 1 NPS NPS 10651037 10651037 1c9x NO 1 1 NPS NPS 11305910 11305910 -- Annotation transfered from 6rsa 1c9y NO 3 3 C3 C3 10813810 10813810 Paper says trimer -- Annotation transfered from 1oth 1ca1 NO 1 1 NPS NPS 9699639 9699639 the molecule is active as a monomer 1ca2 PROBNOT 1 1 NPS NPS 3151019 3151019 9000633 says monomeric -- Annotation transfered from 1uga 1ca3 PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1ca4_1 NO 3 3 C3 C3 10206649 10518213 Paper says trimer - interface conserved with 1kzz (55%) - automatic transfer from 1czy 1ca4_2 NO 3 3 C3 C3 10206649 10518213 Paper says trimer - interface conserved with 1kzz (55%) - automatic transfer from 1czy 1ca9_1 NO 3 3 C3 C3 10206649 10518213 Paper says trimer - interface conserved with 1kzz (55%) - automatic transfer from 1czy 1ca9_2 NO 3 3 C3 C3 10206649 10518213 Paper says trimer - interface conserved with 1kzz (55%) - automatic transfer from 1czy 1caa PROBNOT 1 1 NPS NPS 1303768 1303768 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1iu5 1cad PROBNOT 1 1 NPS NPS 1303768 1303768 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1iu5 1cah PROBNOT 1 1 NPS NPS 1474587 1474587 9000633 says monomeric -- Annotation transfered from 1uga 1cai PROBNOT 1 1 NPS NPS 7901850 7901850 9000633 says monomeric -- Annotation transfered from 1uga 1caj PROBNOT 1 1 NPS NPS 7901850 7901850 9000633 says monomeric -- Annotation transfered from 1uga 1cak PROBNOT 1 1 NPS NPS 7901850 7901850 9000633 says monomeric -- Annotation transfered from 1uga 1cal PROBNOT 1 1 NPS NPS 7901850 7901850 9000633 says monomeric -- Annotation transfered from 1uga 1cam PROBNOT 1 1 NPS NPS 7901850 7901850 9000633 says monomeric -- Annotation transfered from 1uga 1can PROBNOT 1 1 NPS NPS 1336460 1336460 9000633 says monomeric -- Annotation transfered from 1uga 1cao PROBNOT 1 1 NPS NPS 1336460 1336460 9000633 says monomeric -- Annotation transfered from 1uga 1caq PROBNOT 1 1 NPS NPS 10422833 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme 1cay PROBNOT 1 1 NPS NPS 15299482 0 9000633 says monomeric -- Annotation transfered from 1uga 1caz PROBNOT 1 1 NPS NPS 15299482 0 9000633 says monomeric -- Annotation transfered from 1uga 1cb0 NO 3 3 C3 C3 10404592 10404592 Interface conserved with 1v48 (27%) -- Annotation transfered from 1cg6 1cb2_1 PROBNOT 1 1 NPS NPS 8875646 12188666 BU changed since last release and is now corrected - Paper implies monomer - PISA also says monomer - automatic transfer from 1hgw_2 1cb2_2 PROBNOT 1 1 NPS NPS 8875646 12188666 BU changed since last release and is now corrected - Paper implies monomer - PISA also says monomer - automatic transfer from 1hgw_2 1cb4 NO 2 2 C2 C2 10092461 10092461 PAper, SP say dimer -- Annotation transfered from 1cob 1cb5 NO 6 6 D3 D3 10404591 10404591 Interface geometry conserved with 3gcb (38%) -- interesting case of protein evolution because a similar hexamer (same QS) is more divergent (38%) than a monomer (different QS, 1atk, 57%). 1cbg NO 2 2 C2 C2 8535788 8535788 Paper says: Although CBG exists as a homodimer in solution, there is no evidence for catalytic cooperativity. 1cbi NA 2 1 C2 NPS 7563063 9737849 Said to be a monomer in this paper, which looks at the structure with NMR. However, it was shown that it forms dimers at high [.]. So it is an interesting case: apo and holo forms of CRABPI tend to self-associate at high (1.2 mM) concentrations, while at low concentrations (0.2mM), they are predominantly monomeric (10924105) 1cbj NO 2 2 C2 C2 10092461 10092461 PAper, SP say dimer -- Annotation transfered from 1cob 1cbk YES 2 1 C2 NPS 10080886 10080886 The purified protein eluted from an analytical gel filtration column in an elution volume corresponding to a molecular mass of 20 kDa. Quasi-elastic light scattering and sedimentation equilibrium centrifugation experiments performed with the purified protein were consistent with a molecular mass of 20 kDa and 18.5 kDa, respectively. These data are in good agreement with the determined and calculated molecular mass of 18,300 Da and 18,299 Da, respectively, and indicate that HiHPPK is a monomer in solution. -- PISA wrong 1cbl NO 4 4 D2 D2 8114097 8114097 Paper says tetramer -- Annotation transfered from 1cbm 1cbm NO 4 4 D2 D2 8114096 8114096 Paper says tetramer 1cbn PROBNOT 1 1 NPS NPS 8450543 8450543 Although no clear reference was found, it is accepted to me that crambin is at least predominantly monomeric in somution. -- this family is a MESSSS 1cbq PROBYES 3 1 C3 NPS 7704533 9737849 Apo-CRABPII is largely monomeric in solution 1cbr NA 2 1 C2 NPS 7704533 7704533 Said to be a monomer in this paper, which looks at the structure with NMR. However, it was shown that it forms dimers at high [.]. So it is an interesting case: apo and holo forms of CRABPI tend to self-associate at high (1.2 mM) concentrations, while at low concentrations (0.2mM), they are predominantly monomeric (10924105) -- Annotation transfered from 1cbi 1cbs NO 1 1 NPS NPS 7704533 7704533 Apo-CRABPII is largely monomeric in solution -- Annotation transfered from 3cbs 1cc4 YES 1 2 NPS C2 10025942 10025942 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 1cc6 1cc5 PROBNOT 2 2 C2 C2 2993632 2993632 SP and PISA say dimer 1cc6 YES 1 2 NPS C2 10025942 3040401 the enzyme exists mainly as a dimer in solution 1cc7 PROBNOT 1 1 NPS NPS 10404590 10404590 Paper says nothing and PISA says monomer 1cc8 PROBNOT 1 1 NPS NPS 10404590 10404590 Paper says nothing and PISA says monomer -- Annotation transfered from 1cc7 1cca PROBNOT 1 1 NPS NPS 8384877 8384877 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1ccb PROBNOT 1 1 NPS NPS 8384877 8384877 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1ccc PROBNOT 1 1 NPS NPS 8384877 8384877 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1cce PROBNOT 1 1 NPS NPS 7809133 7809133 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1ccg PROBNOT 1 1 NPS NPS 7809133 7809133 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1cci PROBNOT 1 1 NPS NPS 8673607 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1ccj PROBNOT 1 1 NPS NPS 9514261 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1cck PROBNOT 1 1 NPS NPS 7703247 7703247 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1ccl PROBNOT 1 1 NPS NPS 0 0 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1ccp PROBNOT 1 1 NPS NPS 2169873 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1ccr PROBNOT 1 1 NPS NPS 6304326 6304326 1ccs PROBNOT 1 1 NPS NPS 7761440 7761440 9000633 says monomeric -- Annotation transfered from 1uga 1cct PROBNOT 1 1 NPS NPS 7761440 7761440 9000633 says monomeric -- Annotation transfered from 1uga 1ccu PROBNOT 1 1 NPS NPS 7761440 7761440 9000633 says monomeric -- Annotation transfered from 1uga 1cd0 NO 2 2 C2 C2 10524280 10524280 Classic IgV interaction 1cd2 PROBNOT 1 1 NPS NPS 10194348 10194348 PISA also says monomer - Human is monomeric so I guess it should be - Only Thermogota seems to be dimeric 1cd5 NO 6 6 D3 D3 10378272 10378272 SP and EcoCyc say hexamer. 1cd8 NO 2 2 C2 C2 1547508 1547508 Typical homodimer form of IgV - paper confirms 1cdc NO 2 2 C2 C2 7638192 7638192 1cdd PROBNOT 2 2 C2 C2 1631098 1631098 9698564 says: E. coli GarTfase exhibits a pH-dependent monomer-dimer equilibrium with the monomer preferably populated above pH 7.4 and the dimer below pH 6.6 -- pH induced dimerization -- check 12450384 for good summary of the protein 1cde_1 PROBNOT 1 1 NPS NPS 1631098 10606510 BU changed since last release and is now corrected - 9698564 says: E. coli GarTfase exhibits a pH-dependent monomer-dimer equilibrium with the monomer preferably populated above pH 7.4 and the dimer below pH 6.6 -- pH induced dimerization -- this interface is too weak - automaticaly inferred from 1c2t 1cde_2 PROBNOT 1 1 NPS NPS 1631098 10606510 BU changed since last release and is now corrected - 9698564 says: E. coli GarTfase exhibits a pH-dependent monomer-dimer equilibrium with the monomer preferably populated above pH 7.4 and the dimer below pH 6.6 -- pH induced dimerization -- this interface is too weak - automaticaly inferred from 1c2t 1cde_3 PROBNOT 1 1 NPS NPS 1631098 10606510 BU changed since last release and is now corrected - 9698564 says: E. coli GarTfase exhibits a pH-dependent monomer-dimer equilibrium with the monomer preferably populated above pH 7.4 and the dimer below pH 6.6 -- pH induced dimerization -- this interface is too weak - automaticaly inferred from 1c2t 1cde_4 PROBNOT 1 1 NPS NPS 1631098 10606510 BU changed since last release and is now corrected - 9698564 says: E. coli GarTfase exhibits a pH-dependent monomer-dimer equilibrium with the monomer preferably populated above pH 7.4 and the dimer below pH 6.6 -- pH induced dimerization -- this interface is too weak - automaticaly inferred from 1c2t 1cdg NO 1 1 NPS NPS 8107143 8107143 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1cdh PROBYES 2 1 C2 NPS 8075984 8075984 By analytical ultracentrifugation at comparable concentrations, gp120 and CD4 alone were shown to behave as monomers and form a 1:1 complex when mixed (P. Hensley, personal communication), which suggests that self-association was not the root of the deviations. - This doesnt show for sure that there is no association since CD4 is normally in a membranne - But since PISA says monomer, I ll stick to this -- Annotation transfered from 3cd4 1cdi PROBYES 2 1 C2 NPS 8075984 8075984 By analytical ultracentrifugation at comparable concentrations, gp120 and CD4 alone were shown to behave as monomers and form a 1:1 complex when mixed (P. Hensley, personal communication), which suggests that self-association was not the root of the deviations. - This doesnt show for sure that there is no association since CD4 is normally in a membranne - But since PISA says monomer, I ll stick to this -- Annotation transfered from 3cd4 1cdj PROBNOT 1 1 NPS NPS 8986758 8986758 By analytical ultracentrifugation at comparable concentrations, gp120 and CD4 alone were shown to behave as monomers and form a 1:1 complex when mixed (P. Hensley, personal communication), which suggests that self-association was not the root of the deviations. - and PISA says monomer too -- Annotation transfered from 1cdy 1cdk_1 NA 1 1 NPS NPS 8384554 8251932 BU changed since last release and is now corrected - Paper does not mention an oligomer - automaticaly inferred from 1cmk 1cdk_2 NA 1 1 NPS NPS 8384554 8251932 BU changed since last release and is now corrected - Paper does not mention an oligomer - automaticaly inferred from 1cmk 1cdl_1 PROBNOT 1 1 NPS NPS 1519061 3145979 - automatic transfer from 3cln 1cdl_2 PROBNOT 1 1 NPS NPS 1519061 3145979 - automatic transfer from 3cln 1cdl_3 PROBNOT 1 1 NPS NPS 1519061 3145979 - automatic transfer from 3cln 1cdl_4 PROBNOT 1 1 NPS NPS 1519061 3145979 - automatic transfer from 3cln 1cdm PROBNOT 1 1 NPS NPS 8259515 8259515 -- Annotation transfered from 3cln 1cdo NO 2 2 C2 C2 8845755 8845755 Interface geometry conserved with 1piw (22%) 1cdp PROBNOT 2 2 C2 C2 2777802 2777802 Sedimentation equilibrium analysis results show that the EF fragment exists in a monomer-dimer equilibrium when complexed with La3+ // This symmetry is conserved with 1b8c. Not very clear though -- Annotation transfered from 5cpv 1cdt NA 2 2 C2 C2 2370666 2370666 Ask the persons who work with it 1cdu PROBNOT 1 1 NPS NPS 8986758 8986758 By analytical ultracentrifugation at comparable concentrations, gp120 and CD4 alone were shown to behave as monomers and form a 1:1 complex when mixed (P. Hensley, personal communication), which suggests that self-association was not the root of the deviations. - and PISA says monomer too -- Annotation transfered from 1cdy 1cdw NO 1 1 NPS NPS 8643494 8643494 Paper says: Photon correlation spectroscopy (PCS) documented that TBP is a dimer in solution in the absence of DNA and undergoes a dimer-to-monomer transition upon binding to oligonucleotides containing the TATA-consensus sequence. - Here there is DNA so it is normal - DNA induced monomer ! 1cdy PROBNOT 1 1 NPS NPS 8986758 8986758 By analytical ultracentrifugation at comparable concentrations, gp120 and CD4 alone were shown to behave as monomers and form a 1:1 complex when mixed (P. Hensley, personal communication), which suggests that self-association was not the root of the deviations. - and PISA says monomer too 1ce0 NO 3 3 C3 C3 10220324 10220324 Paper says trimer 1ce5 PROBNOT 1 1 NPS NPS 10651279 10651279 -- Annotation transfered from 1az8 1ce8 PROBNOT 8 8 D2 D2 10428826 11551199 Carbamoyl phosphate synthetase (CPS) from Escherichia coli is allosterically regulated by the metabolites ornithine, IMP, and UMP. Ornithine and IMP function as activators, whereas UMP is an inhibitor. CPS undergoes changes in the state of oligomerization that are dependent on the protein concentration and the binding of allosteric effectors. Ornithine and IMP promote the formation of an (ab)4 tetramer while UMP favors the formation of an (ab)2 dimer. Propagate to all (CPS) please! -) -- Annotation transfered from 1bxr 1ce9 YES 4 2 C2 C2 10329176 10329176 Paper says dimer 1cea_1 PROBNOT 1 1 NPS NPS 8611560 8054447 Real protein 4500 aa! So monomeric seems right - automatic transfer from 1pkr 1cea_2 PROBNOT 1 1 NPS NPS 8611560 8054447 Real protein 4500 aa! So monomeric seems right - automatic transfer from 1pkr 1ceb_1 PROBNOT 1 1 NPS NPS 8611560 8054447 Real protein 4500 aa! So monomeric seems right - automatic transfer from 1pkr 1ceb_2 PROBNOT 1 1 NPS NPS 8611560 8054447 Real protein 4500 aa! So monomeric seems right - automatic transfer from 1pkr 1cef PROBNOT 1 1 NPS NPS 7626623 7626623 the Streptomyces R61 and Actinomadura R39 DD-peptidases, are water-soluble monomeric proteins; (12723972) -- Annotation transfered from 1pwd 1ceg PROBNOT 1 1 NPS NPS 7626623 7626623 the Streptomyces R61 and Actinomadura R39 DD-peptidases, are water-soluble monomeric proteins; (12723972) -- Annotation transfered from 1pwd 1ceh PROBYES 2 1 C2 NPS 7703854 7703854 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1bpq 1cei YES 2 1 C2 NPS 8692833 9639578 BU changed since last release and is now incorrect - we found that Im7 only ever exists in solution as a monomer, even up to protein concentrations of 15 mg/ml 1cel_1 PROBNOT 1 1 NPS NPS 8036495 9466911 None of the papers speaks about a dimer - a dimer is found using PISA but visual inspection reveals a weak interface. - automatic transfer from 6cel 1cel_2 PROBNOT 1 1 NPS NPS 8036495 9466911 None of the papers speaks about a dimer - a dimer is found using PISA but visual inspection reveals a weak interface. - automatic transfer from 6cel 1ceq NO 4 4 D2 D2 10187806 10187806 SP says tetramer -- Annotation transfered from 1ldg 1ces NO 4 4 D2 D2 8663112 8663112 SP says tetramer -- Annotation transfered from 1cjp 1cet NO 4 4 D2 D2 10187806 10187806 SP says tetramer -- Annotation transfered from 1ldg 1cev YES 6 6 D3 D3 10196128 10196128 Interface geometry conserved with 1gq6 (28%) -- bad interface -- interesting as the geometry of the trimers varies. 1cf0_1 PROBNOT 1 1 NPS NPS 10404225 10404225 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio - automaticaly inferred from 1cjf 1cf0_2 PROBNOT 1 1 NPS NPS 10404225 10404225 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio - automaticaly inferred from 1cjf 1cf2 NO 4 4 D2 D2 10393306 10393306 interface geometry conserved with 1npt (22%) 1cf3 YES 1 2 NPS C2 10216293 10216293 Paper says dimer -- PISA misses it as well 1cfj PROBNOT 1 1 NPS NPS 10353814 10353814 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1cfm PROBYES 3 1 NS NPS 10869174 10869174 Paper says: distorted proper 2-fold rotation. This may represent the dimeric relation of the monomers in situ; however, the heme orientation suggested by this model is not consistent with previous EPR measurements on oriented membranes. 1cg2 YES 4 2 D2 C2 9083113 9083113 Paper says dimer: The enzyme studied here, carboxypeptidase G2 (CPG2), is a zinc-dependent metalloenzyme produced by Pseudomonas sp. strain RS-16 as a homodimer of molecular weight 2 × 41 800 Da 1cg6 NO 3 3 C3 C3 10404592 10404592 Interface conserved with 1v48 (27%) 1cge PROBNOT 1 1 NPS NPS 8031754 8031754 No clear evidence after a quick search but PISA agrees ... -- Annotation transfered from 1hfc 1cgf_1 PROBNOT 1 1 NPS NPS 8031754 8090713 No clear evidence after a quick search but PISA agrees ... - automatic transfer from 1hfc 1cgf_2 PROBNOT 1 1 NPS NPS 8031754 8090713 No clear evidence after a quick search but PISA agrees ... - automatic transfer from 1hfc 1cgh PROBNOT 1 1 NPS NPS 8896442 8896442 Paper says nothing - PISA says monomer 1cgk NO 2 2 C2 C2 10426957 10426957 -- Annotation transfered from 1d6f 1cgl_1 PROBNOT 1 1 NPS NPS 8278810 8090713 No clear evidence after a quick search but PISA agrees ... - automatic transfer from 1hfc 1cgl_2 PROBNOT 1 1 NPS NPS 8278810 8090713 No clear evidence after a quick search but PISA agrees ... - automatic transfer from 1hfc 1cgn NO 2 2 C2 C2 15299707 0 Paper says dimer -- Annotation transfered from 1e84 1cgo NO 2 2 C2 C2 15299707 0 Paper says dimer -- Annotation transfered from 1e84 1cgt NO 1 1 NPS NPS 1826034 1826034 Paper says monomeric: Cyclodextrin glycosyltransferases (CGTases, EC 2.4.1.19) are of bacterial origin and are monomeric. They catalyze the -- Annotation transfered from 7cgt 1cgu NO 1 1 NPS NPS 1390660 1390660 Paper says monomeric: Cyclodextrin glycosyltransferases (CGTases, EC 2.4.1.19) are of bacterial origin and are monomeric. They catalyze the -- Annotation transfered from 7cgt 1cgv NO 1 1 NPS NPS 7880832 7880832 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1cgw NO 1 1 NPS NPS 7880832 7880832 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1cgx NO 1 1 NPS NPS 7880832 7880832 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1cgy NO 1 1 NPS NPS 7880832 7880832 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1cgz NO 2 2 C2 C2 10426957 10426957 -- Annotation transfered from 1d6f 1ch1 NO 1 1 NPS NPS 11084036 11084036 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1ch2 NO 1 1 NPS NPS 11084036 11084036 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1ch3 NO 1 1 NPS NPS 11084036 11084036 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1ch4 NO 4 4 D2 D2 10080899 10080899 Paper says tetramer 1ch5 NO 1 1 NPS NPS 11084036 11084036 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1ch7 NO 1 1 NPS NPS 11084036 11084036 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1ch9 NO 1 1 NPS NPS 11084036 11084036 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1chg NA 1 1 NPS NPS 5442169 3980476 They explain in the paper (3980476) that chymotrypsin can form an asymetric dimer, but can also be found as a monomer in particular conditions. Here PISA says monomer. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 1ex3 1chh PROBYES 2 1 C2 NPS 7819192 7819192 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1cih 1chi PROBYES 2 1 C2 NPS 7819192 7819192 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1cih 1chj PROBYES 2 1 C2 NPS 7819192 7819192 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1cih 1chm PROBNOT 2 2 C2 C2 1696320 1696320 SP says dimer 1chn NO 1 1 NPS NPS 8176739 2999789 CheY is a Mr 14,000 monomeric protein 1chr NO 8 8 D4 D4 15299479 15299479 Paper says octamer 1chu PROBYES 2 1 C2 NPS 10425677 10425677 SP says monomer 1chw NO 2 2 C2 C2 10426957 10426957 BU changed since last release and is now corrected - bad reconstruction 1chz PROBNOT 1 1 NPS NPS 10666623 10666623 Paper mentions that BMK M1 are monomeric -- Annotation transfered from 1t7b 1ci1 NO 2 2 C2 C2 10468562 10468562 Interface geometry conserved with 1m6j (45%) - paper says dimer 1ci7 NO 2 2 C2 C2 10529228 10529228 Paper says dimer 1ci8 PROBYES 2 1 C2 NPS 11847270 11847270 Paper says nothing, related proteins are monomeric, PISA says monomer 1ci9 PROBYES 2 1 C2 NPS 11847270 11847270 Paper says nothing, related proteins are monomeric, PISA says monomer -- Annotation transfered from 1ci8 1cia PROBNOT 3 3 C3 C3 7906544 7906544 SP says trimer -- PISA very wrong -- Annotation transfered from 3cla 1cie PROBYES 2 1 C2 NPS 7711047 7711047 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1cih 1cif PROBYES 2 1 C2 NPS 7711047 7711047 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1cih 1cig PROBNOT 1 1 NPS NPS 7711047 7711047 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1crh 1cih PROBYES 2 1 C2 NPS 7711047 7757009 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) 1cij NO 1 1 NPS NPS 10508409 10508409 SP says monomer -- Annotation transfered from 1edb 1cik NO 1 1 NPS NPS 11084036 11084036 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1cil PROBNOT 1 1 NPS NPS 8142888 8142888 9000633 says monomeric -- Annotation transfered from 1uga 1cim PROBNOT 1 1 NPS NPS 8142888 8142888 9000633 says monomeric -- Annotation transfered from 1uga 1cin PROBNOT 1 1 NPS NPS 8142888 8142888 9000633 says monomeric -- Annotation transfered from 1uga 1cio NO 1 1 NPS NPS 11084036 11084036 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1cip PROBNOT 1 1 NPS NPS 10358003 10358003 Normally part of a heterotrimer, so apparently no homo-interaction. -- Annotation transfered from 1gdd 1cit NO 1 1 NPS NPS 10331876 10331876 Only one binding site on the DNA 1ciu PROBNOT 1 1 NPS NPS 8604143 8604143 Paper says nothing but Cyclodextrin-glycosyltransferase are monomeric - PISA also says so. -- Annotation transfered from 1a47 1civ NO 2 2 C2 C2 10196131 10196131 Paper say dimer 1ciw NO 4 4 C2 C2 10417405 10417405 Paper says tetramer -- Annotation transfered from 2pel 1ciz PROBNOT 1 1 NPS NPS 10422833 10422833 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme -- Annotation transfered from 1caq 1cj0 YES 2 4 C2 D2 10387080 10387080 Most other closely related enzymes are described as tetrameric and PISA can finds a tetramer with this one 1cj2 NA 2 2 C2 C2 10493859 10493859 the enzyme exists mainly as a dimer in solution -- But this interface is wrong - PISA finds the right one - Even though this interface is weaker than the other one, it is interesting to note that its geometry is conserved with 1ojb (40% simil) - very interesting 1cj3 NA 2 2 C2 C2 10493859 10493859 the enzyme exists mainly as a dimer in solution -- But this interface is wrong - PISA finds the right one - Even though this interface is weaker than the other one, it is interesting to note that its geometry is conserved with 1ojb (40% simil) - very interesting 1cj4 NA 2 2 C2 C2 10493859 10493859 the enzyme exists mainly as a dimer in solution -- But this interface is wrong - PISA finds the right one - Even though this interface is weaker than the other one, it is interesting to note that its geometry is conserved with 1ojb (40% simil) - very interesting 1cj6 NO 1 1 NPS NPS 10504240 10504240 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1cj7 NO 1 1 NPS NPS 10504240 10504240 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1cj8 NO 1 1 NPS NPS 10504240 10504240 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1cj9 NO 1 1 NPS NPS 10504240 10504240 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1cjb YES 4 4 NS D2 10433693 10433693 BU changed since last release and is now incorrect - Interface conserved 1cjc NO 1 1 NPS NPS 10369776 15134648 SP says monomer - Paper says: FNRs (EC 1.18.1.2) are ubiquitous, monomeric enzymes harbouring one molecule of noncovalently bound FAD as prosthetic group [1, 2, 3 and 4]. They catalyse the reversible electron transfer between NADP(H) and the iron-sulfur protein ferredoxin (Fd) or FMN-containing flavodoxin (Fld). 1cje_1 PROBYES 2 1 C2 NPS 10620322 9551550 Paper says nothing, PISA implies monomer - automatic transfer from 1ayf 1cje_2 PROBYES 2 1 C2 NPS 10620322 9551550 Paper says nothing, PISA implies monomer - automatic transfer from 1ayf 1cjf PROBYES 2 1 C2 NPS 10404225 10404225 BU changed since last release and is now incorrect - SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio 1cjl PROBNOT 1 1 NPS NPS 8896443 8896443 SP says: Dimer of a heavy and a light chain linked by disulfide bonds (so heterodimer). 1cjm PROBNOT 1 1 NPS NPS 10543947 10543947 Paper says nothing, PISA says monomer 1cjp NO 4 4 D2 D2 9087912 9087912 SP says tetramer 1cjx NO 4 4 D2 D2 10467142 10467142 Paper says tetramer 1ck1 NA 2 2 C2 NPS 11934896 11934896 Paper says that a non-symmetric dimer is relevant: the homodimerization does not appear to be an artifact of the crystal environment. The same zinc-mediated dimerization was observed in the SEC2 crystal structure (14) that was grown under different conditions. A similar zinc-induced homodimerization has been also observed in human growth hormone (39). -- zinc induced dimerization 1ck3 PROBNOT 1 1 NPS NPS 10423234 10423234 EcoCyc says monomer -- Annotation transfered from 1jwp 1ck6 PROBNOT 1 1 NPS NPS 10504224 10504224 Peroxidases seem to be monomeric in general -- Annotation transfered from 1gza 1cka PROBNOT 1 1 NPS NPS 7735837 7735837 Paper says nothing, related structures are monomers and PISA says monomer -- Annotation transfered from 1b07 1ckb PROBNOT 1 1 NPS NPS 7735837 7735837 Paper says nothing, related structures are monomers and PISA says monomer -- Annotation transfered from 1b07 1ckc NO 1 1 NPS NPS 10504240 10504240 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ckd NO 1 1 NPS NPS 10504240 10504240 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ckf NO 1 1 NPS NPS 10504240 10504240 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ckg YES 2 2 NS NPS 10504240 10504240 1ckh NO 1 1 NPS NPS 10504240 10504240 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1cki NA 2 1 NS NPS 8648628 8648628 SP says monomer - Paper says nothin - PISA says dimer, wrong? -- Annotation transfered from 1ckj 1ckj NA 2 1 NS NPS 8648628 8648628 SP says monomer - Paper says nothin - PISA says dimer, wrong? 1ckp NO 1 1 NPS NPS 9677190 9677190 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1cks NO 6 6 D3 D3 8211159 8211159 Domain swapped hexamer 1cku PROBNOT 2 2 C2 C2 10531472 10531472 The protein seem to be in a monomer dimer equilibrium (12077426 EPR and NMR studies have shown that HiPIPs might dimerize in the solution through their hydrophobic surfaces, a discovery that has led to important insights regarding the electron-transfer pathway - in the NMR reference, they say F48 is at the interface and this is the case here so maybe this dimer is relevant) 1cl0 NO 2 2 C2 C2 10595539 10595539 Interface conserved with 1fl2 (33%) 1cl1 PROBNOT 4 4 D2 D2 8831789 8831789 1cl2 PROBNOT 4 4 D2 D2 9376370 9376370 -- Annotation transfered from 1cl1 1cl5_1 PROBNOT 1 1 NPS NPS 10686108 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 1cl5_2 PROBNOT 1 1 NPS NPS 10686108 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 1cl6 PROBNOT 1 1 NPS NPS 10671516 10671516 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer -- Annotation transfered from 1cmj 1cla PROBNOT 3 3 C3 C3 2109633 2109633 SP says trimer -- PISA very wrong -- Annotation transfered from 3cla 1cle_1 PROBYES 1 2 NPS C2 7788294 12499539 BU changed since last release and is now incorrect - Paper says homodimer - automaticaly inferred from 1llf 1cle_2 PROBYES 1 2 NPS C2 7788294 12499539 BU changed since last release and is now incorrect - Paper says homodimer - automaticaly inferred from 1llf 1clk NO 4 4 D2 D2 10666592 10666592 1cll PROBNOT 1 1 NPS NPS 1474585 1474585 -- Annotation transfered from 3cln 1clm NO 1 1 NPS NPS 8453381 8453381 -- Annotation transfered from 1exr 1clu NO 1 1 NPS NPS 10359839 10359839 Ras proteins are monomeric G proteins -- Annotation transfered from 1ctq 1clw YES 1 3 NPS C3 10543960 10543960 Paper says trimer -- Annotation transfered from 1qa1 1clx_1 PROBYES 2 2 C2 C2 15299710 11025547 They say in the paper that there is no evidence that it forms dimers in solution - automatic transfer from 1e5n 1clx_2 PROBYES 2 2 C2 C2 15299710 11025547 They say in the paper that there is no evidence that it forms dimers in solution - automatic transfer from 1e5n 1cm1 PROBNOT 1 1 NPS NPS 9438860 9438860 -- Annotation transfered from 3cln 1cm2 NO 1 1 NPS NPS 10419492 9334229 E. coli HPr is a small, monomeric protein 1cm3 NO 1 1 NPS NPS 10419492 10419492 E. coli HPr is a small, monomeric protein -- Annotation transfered from 1cm2 1cm4_1 PROBNOT 1 1 NPS NPS 9438860 3145979 - automatic transfer from 3cln 1cm4_2 PROBNOT 1 1 NPS NPS 9438860 3145979 - automatic transfer from 3cln 1cm4_3 PROBNOT 1 1 NPS NPS 9438860 3145979 - automatic transfer from 3cln 1cm4_4 PROBNOT 1 1 NPS NPS 9438860 3145979 - automatic transfer from 3cln 1cm5 NO 2 2 C2 C2 10504733 10504733 -- Annotation transfered from 3pfl 1cm9 PROBNOT 2 2 C2 C2 11041848 11041848 vMIP-II is a monomer at millimolar concentrations - but the dimer is similar in related proteins so it is relevant. 1cmj PROBNOT 1 1 NPS NPS 10671516 10671516 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer 1cmk NA 6 1 D3 NPS 8251932 8251932 Paper does not mention an oligomer 1cml NO 2 2 C2 C2 10426957 10426957 -- Annotation transfered from 1d6f 1cmn PROBNOT 1 1 NPS NPS 10671516 10671516 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer -- Annotation transfered from 1cmj 1cmp PROBNOT 1 1 NPS NPS 8142383 8142383 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1cmq PROBNOT 1 1 NPS NPS 8142383 8142383 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1cmt PROBNOT 1 1 NPS NPS 8528082 8528082 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1cmu PROBNOT 1 1 NPS NPS 8528082 8528082 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1cn1 PROBNOT 4 4 D2 D2 490645 490645 1cnb PROBNOT 1 1 NPS NPS 7803386 7803386 9000633 says monomeric -- Annotation transfered from 1uga 1cnc PROBNOT 1 1 NPS NPS 7803386 0 9000633 says monomeric -- Annotation transfered from 1uga 1cng PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1cnh PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1cni PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1cnj PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1cnk PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1cnm PROBNOT 1 1 NPS NPS 10737944 0 BU changed since last release and is now corrected - 1cnq NO 4 4 D2 D2 9708979 9708979 -- Annotation transfered from 1eyi 1cnr PROBNOT 1 1 NPS NPS 8188676 8188676 Although no clear reference was found, it is accepted to me that crambin is at least predominantly monomeric in somution. -- this family is a MESSSS -- Annotation transfered from 1cbn 1cnv PROBNOT 1 1 NPS NPS 7490746 16663793 1cnw PROBNOT 1 1 NPS NPS 7608893 7608893 9000633 says monomeric -- Annotation transfered from 1uga 1cnx PROBNOT 1 1 NPS NPS 7608893 7608893 9000633 says monomeric -- Annotation transfered from 1uga 1cny PROBNOT 1 1 NPS NPS 7608893 7608893 9000633 says monomeric -- Annotation transfered from 1uga 1co6 PROBNOT 1 1 NPS NPS 7674304 7674304 1co8 NO 1 1 NPS NPS 11084036 11084036 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1co9 NO 1 1 NPS NPS 11084036 11084036 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1coa NA 12 12 D6 D6 8218191 8218191 PISA says dodecamer, I dont know: 1ypb which is very similar has a diPISA says dodecamer, I dont know: 1ypb which is very similar has a different crystal packingfferent crystal packing 1cob NO 2 2 C2 C2 1619651 1619651 PAper, SP say dimer 1coj NO 4 4 D2 D2 9236127 9236127 Paper says tetramer 1com_1 NO 3 3 C3 C3 8046752 8046752 Interface conserved with 1jd1 (0% id) 1com_2 NO 3 3 C3 C3 8046752 8046752 Interface conserved with 1jd1 (0% id) -- Annotation transfered from 1com_1 1com_3 NO 3 3 C3 C3 8046752 8046752 Interface conserved with 1jd1 (0% id) -- Annotation transfered from 1com_1 1com_4 NO 3 3 C3 C3 8046752 8046752 Interface conserved with 1jd1 (0% id) -- Annotation transfered from 1com_1 1con NO 4 4 D2 D2 15299493 0 SP says tetramer -- Annotation transfered from 1cjp 1cos PROBNOT 3 3 NS NS 8446897 8446897 triple helix coil -- error in symmetry search? 1coz NO 2 2 C2 C2 10508782 10508782 interesting - family is hexameric but this protein is dimeric and active site is at the interface - (cf summary) - Given that I thought that evolutionary pathway is often the assembly one, this could be a counter example. 1cp0 NO 1 1 NPS NPS 11084036 11084036 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1cp4 PROBNOT 1 1 NPS NPS 2261467 2261467 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1cp5 NO 1 1 NPS NPS 11084036 11084036 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1cp6 NO 1 1 NPS NPS 10413478 10413478 Aminopeptidase from Aeromonas proteolytica (AAP) is a small, monomeric enzyme (32KDa) 1cp7 PROBNOT 1 1 NPS NPS 10771423 10771423 SwissProt says monomer -- Annotation transfered from 1f2o 1cpd PROBNOT 1 1 NPS NPS 7972020 7972020 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1cpe PROBNOT 1 1 NPS NPS 7972020 7972020 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1cpf PROBNOT 1 1 NPS NPS 7972020 7972020 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1cpg PROBNOT 1 1 NPS NPS 7972020 7972020 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1cpi NO 2 2 C2 C2 -1 0 -- Annotation transfered from 1ajx 1cpj PROBYES 2 1 C2 NPS 7890671 7890671 SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) -- Annotation transfered from 1cte 1cpq PROBNOT 1 1 NPS NPS 8676382 8676382 Most cytochromes c prime are dimeric with each molecule comprising a left-handed four-a-helix bundle with a heme group attached to a Cys-X-X-Cys-His site near the carboxyl terminus. However, Rhodobacter capsulatus and R. sphaeroides cytochromes c prime appear to exist as equilibrium mixtures of monomers and dimers, and only R. palustris cytochrome c prime is completely monomeric(Cusanovich, 1971). -- Annotation transfered from 1cpr 1cpr PROBNOT 1 1 NPS NPS 15299853 15299853 Most cytochromes c prime are dimeric with each molecule comprising a left-handed four-a-helix bundle with a heme group attached to a Cys-X-X-Cys-His site near the carboxyl terminus. However, Rhodobacter capsulatus and R. sphaeroides cytochromes c prime appear to exist as equilibrium mixtures of monomers and dimers, and only R. palustris cytochrome c prime is completely monomeric(Cusanovich, 1971). 1cpw NO 1 1 NPS NPS 11084036 11084036 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1cpy PROBNOT 1 1 NPS NPS -1 0 Paper says: The structure of monomeric serine carboxypeptidase from Saccharomyces cerevisiae -- Annotation transfered from 1ysc 1cq6 NO 2 2 C2 C2 10858450 10858450 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1cq7 NO 2 2 C2 C2 10858450 10858450 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1cq8 NO 2 2 C2 C2 10858450 10858450 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1cq9 NO 4 4 C2 C2 11288176 11288176 Paper says tetramer -- Annotation transfered from 2pel 1cqa PROBNOT 1 1 NPS NPS 9016715 9016715 SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio 1cqe NO 2 2 C2 C2 8121489 8121489 1cqm_1 NA 1 2 NPS C2 10944185 10944185 BU changed since last release and is now incorrect - They show a tetrameric assembly in the paper but crosslinking exp yields smears, showing random oligomerization. -- Very strange protein ... nonetheless interesting - automaticaly inferred from 1qjh 1cqm_2 NA 1 2 NPS C2 10944185 10944185 BU changed since last release and is now incorrect - They show a tetrameric assembly in the paper but crosslinking exp yields smears, showing random oligomerization. -- Very strange protein ... nonetheless interesting - automaticaly inferred from 1qjh 1cqn_1 NA 1 2 NPS C2 10944185 10944185 BU changed since last release and is now incorrect - They show a tetrameric assembly in the paper but crosslinking exp yields smears, showing random oligomerization. -- Very strange protein ... nonetheless interesting - automaticaly inferred from 1qjh 1cqn_2 NA 1 2 NPS C2 10944185 10944185 BU changed since last release and is now incorrect - They show a tetrameric assembly in the paper but crosslinking exp yields smears, showing random oligomerization. -- Very strange protein ... nonetheless interesting - automaticaly inferred from 1qjh 1cqp_1 PROBNOT 1 1 NPS NPS 10493852 7479767 BU changed since last release and is now corrected - Interface very small - probably monomer - automaticaly inferred from 1lfa 1cqp_2 PROBNOT 1 1 NPS NPS 10493852 7479767 BU changed since last release and is now corrected - Interface very small - probably monomer - automaticaly inferred from 1lfa 1cqr_1 PROBNOT 1 1 NPS NPS 10543949 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1cqr_2 PROBNOT 1 1 NPS NPS 10543949 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1cqs NO 2 2 C2 C2 10653633 10653633 -- Annotation transfered from 1e3v 1cqv PROBNOT 1 1 NPS NPS 11526318 11526318 dimer not mentioned in literature, PISA says monomer -- Annotation transfered from 1i4p 1cqw PROBNOT 1 1 NPS NPS 10587433 10587433 Paper mentions size exclusion column but no oligomer, PISA says monomer -- Annotation transfered from 1bn6 1cr0 NO 6 6 NS NS 10535735 10535735 Open ring 1cr1 NO 6 6 NS NS 10535735 10535735 Open ring -- Annotation transfered from 1cr0 1cr2 NO 6 6 NS NS 10535735 10535735 Open ring -- Annotation transfered from 1cr0 1cr4 NO 6 6 NS NS 10535735 10535735 Open ring -- Annotation transfered from 1cr0 1cr7_1 NO 4 4 C2 C2 11288176 8656429 Paper says tetramer - automatic transfer from 2pel 1cr7_2 NO 4 4 C2 C2 11288176 8656429 Paper says tetramer - automatic transfer from 2pel 1cra PROBNOT 1 1 NPS NPS 8331673 8331673 9000633 says monomeric -- Annotation transfered from 1uga 1crb PROBNOT 1 1 NPS NPS 7683727 7683727 RBPs are monomeric 1crc_1 PROBNOT 1 1 NPS NPS 8591047 2166170 - automatic transfer from 1hrc 1crc_2 PROBNOT 1 1 NPS NPS 8591047 2166170 - automatic transfer from 1hrc 1crg PROBNOT 1 1 NPS NPS 8114094 8114094 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1crh 1crh PROBNOT 1 1 NPS NPS 8114094 7757009 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) 1cri PROBNOT 1 1 NPS NPS 8114094 8114094 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1crh 1crj PROBYES 2 1 C2 NPS 8114094 8114094 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1cih 1crk NO 8 8 D4 D4 8692275 8692275 Interface geometry conserved with 1qk1 (84%) 1crl NO 1 1 NPS NPS 8509417 8509417 interesting: change of oligomeric state is associated with activity - the open form of the lipase is found to be present in solution as a dimer, whereas the closed form appears to be a monomer (pid=11084600). -- Annotation transfered from 1trh 1crm NO 1 1 NPS NPS -1 0 10529183 says monomer 1crn PROBNOT 1 1 NPS NPS 16593516 0 Although no clear reference was found, it is accepted to me that crambin is at least predominantly monomeric in solution. -- this family is a MESSSS -- Annotation transfered from 1cbn 1crw NO 4 4 D2 D2 10806086 10806086 SP says homotetramer - papers too -- Annotation transfered from 1szj 1crx YES 2 4 NS C4 9288963 9288963 Paper shows a tetramer, is generally a tetramer, and PISA do find a cyclic tetramer. So the interfaces do exist in the crystal! 1cry PROBNOT 1 1 NPS NPS 15299438 0 -- Annotation transfered from 1co6 1cs0 PROBNOT 8 8 D2 D2 10587438 11551199 Carbamoyl phosphate synthetase (CPS) from Escherichia coli is allosterically regulated by the metabolites ornithine, IMP, and UMP. Ornithine and IMP function as activators, whereas UMP is an inhibitor. CPS undergoes changes in the state of oligomerization that are dependent on the protein concentration and the binding of allosteric effectors. Ornithine and IMP promote the formation of an (ab)4 tetramer while UMP favors the formation of an (ab)2 dimer. Propagate to all (CPS) please! -) -- Annotation transfered from 1bxr 1cs1 NO 4 4 D2 D2 9843488 9843488 Paper says tetramer - interesting: 40% sim with 1pff but developped 2 new extensive contacts. Any functional importance? 1cs3 YES 1 2 NPS C2 10537309 10537309 There is a very large interface! (>30 residues) 1cs8 PROBNOT 1 1 NPS NPS 0 0 SP says: Dimer of a heavy and a light chain linked by disulfide bonds (so heterodimer). -- Annotation transfered from 1cjl 1csc NO 2 2 C2 C2 2043640 2043640 Interface geometry conserved with 1a59 (27%) -- Annotation transfered from 6cts 1csh NO 2 2 C2 C2 8011640 8011640 Interface geometry conserved with 1a59 (27%) -- Annotation transfered from 6cts 1csi NO 2 2 C2 C2 8011640 8011640 Interface geometry conserved with 1a59 (27%) -- Annotation transfered from 6cts 1csj PROBYES 2 1 C2 NPS 10557268 12438577 HCV RdRp exists primarily as a monomer 1csn PROBYES 2 1 C2 NPS 7889932 7889932 Origonal paper says nothing - CK1 usually accepted as monomeric (cf paper). -- Annotation transfered from 2csn 1csp PROBNOT 1 1 NPS NPS 8321288 8321288 The difference in the self-association of CspB in the presence and absence of phosphate was supported by size-exclusion chromatography - phosphate-induced dimerization -- Annotation transfered from 1csq 1csq PROBNOT 1 1 NPS NPS 8321288 7703860 The difference in the self-association of CspB in the presence and absence of phosphate was supported by size-exclusion chromatography - phosphate-induced dimerization 1csr NO 2 2 C2 C2 7492547 7492547 Interface geometry conserved with 1a59 (27%) -- Annotation transfered from 6cts 1css NO 2 2 C2 C2 7492547 7492547 Interface geometry conserved with 1a59 (27%) -- Annotation transfered from 6cts 1csu PROBYES 2 1 C2 NPS 7757009 7757009 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1cih 1csv PROBNOT 1 1 NPS NPS 7757009 7757009 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1crh 1csw PROBNOT 1 1 NPS NPS 7757009 7757009 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1crh 1csx PROBNOT 1 1 NPS NPS 7757009 7757009 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1crh 1cte PROBYES 2 1 C2 NPS 7890671 7890671 SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) 1ctj PROBNOT 1 1 NPS NPS 8591027 8591027 SP says monomer 1ctn PROBYES 2 1 C2 NPS 7704527 9495026 The weight they find in that paper is compatible with a monomer 1ctp PROBYES 2 1 C2 NPS 15299513 8251932 Paper doe not mention a oligomer 1ctq NO 1 1 NPS NPS 10574788 10574788 Ras proteins are monomeric G proteins 1ctr PROBNOT 1 1 NPS NPS 7803388 7803388 -- Annotation transfered from 3cln 1cts NO 2 2 C2 C2 7120407 7120407 Interface geometry conserved with 1a59 (27%) -- Annotation transfered from 6cts 1ctw NO 1 1 NPS NPS 10545167 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1ctx NA 2 2 C2 C2 6930640 6930640 Ask the persons who work with it -- Annotation transfered from 2ctx 1cty PROBNOT 1 1 NPS NPS 8308895 8308895 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1crh 1ctz PROBNOT 1 1 NPS NPS 8308895 8308895 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1crh 1cu0 NO 1 1 NPS NPS 10545167 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1cu2 NO 1 1 NPS NPS 10545167 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1cu3 NO 1 1 NPS NPS 10545167 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1cu5 NO 1 1 NPS NPS 10545167 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1cu6 NO 1 1 NPS NPS 10545167 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1cuk NO 4 4 C4 C4 8832889 8832889 Paper says tetramer -- Annotation transfered from 1hjp 1cuo PROBNOT 1 1 NPS NPS 14516747 14516747 1cup NO 1 1 NPS NPS 10545167 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1cuq NO 1 1 NPS NPS 10545167 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1cv0 NO 1 1 NPS NPS 10545167 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1cv1 NO 1 1 NPS NPS 10545167 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1cv2 NO 1 1 NPS NPS 11087355 11087355 SP says monomer -- Annotation transfered from 1g42 1cv3 NO 1 1 NPS NPS 10545167 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1cv4 NO 1 1 NPS NPS 10545167 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1cv5 NO 1 1 NPS NPS 10545167 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1cv6 NO 1 1 NPS NPS 10545167 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1cv7 NO 1 1 NPS NPS 0 0 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1cva PROBNOT 1 1 NPS NPS 8262987 8262987 9000633 says monomeric -- Annotation transfered from 1uga 1cvb PROBNOT 1 1 NPS NPS 8262987 8262987 9000633 says monomeric -- Annotation transfered from 1uga 1cvc PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1cvd PROBNOT 1 1 NPS NPS 7803386 7803386 9000633 says monomeric -- Annotation transfered from 1uga 1cve PROBNOT 1 1 NPS NPS 7803386 7803386 9000633 says monomeric -- Annotation transfered from 1uga 1cvf PROBNOT 1 1 NPS NPS 7803386 7803386 9000633 says monomeric -- Annotation transfered from 1uga 1cvh PROBNOT 1 1 NPS NPS 7803386 7803386 9000633 says monomeric -- Annotation transfered from 1uga 1cvk NO 1 1 NPS NPS 10545167 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1cvl PROBNOT 1 1 NPS NPS 8683577 8683577 SP says monomer - PISA too 1cvn NO 4 4 D2 D2 8557713 8557713 SP says tetramer -- Annotation transfered from 1cjp 1cvu NO 2 2 C2 C2 10811226 10811226 1cvz PROBNOT 1 1 NPS NPS 10600517 10600517 Papain is a 23,400-dalton single polypeptide -- Annotation transfered from 9pap 1cw2 NO 4 4 C2 C2 10504236 10504236 Paper says a2b2 -- Annotation transfered from 2wsy 1cwa PROBNOT 1 1 NPS NPS 8263916 8263916 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 1cwb PROBNOT 1 1 NPS NPS 8073029 8073029 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 1cwc PROBNOT 1 1 NPS NPS 7966126 7966126 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 1cwd PROBNOT 1 1 NPS NPS 7532720 7532720 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 -- Annotation transfered from 1lkk 1cwe PROBYES 2 1 C2 NPS 7532720 7532720 1cwf PROBNOT 1 1 NPS NPS 9769216 9769216 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 1cwh_1 PROBNOT 1 1 NPS NPS 9769216 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1cwi PROBNOT 1 1 NPS NPS 9769216 9769216 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 1cwj PROBNOT 1 1 NPS NPS 9769216 9769216 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 1cwk PROBNOT 1 1 NPS NPS 9769216 9769216 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 1cwl_1 PROBNOT 1 1 NPS NPS 9769216 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1cwm PROBNOT 1 1 NPS NPS 9769216 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1cwn NO 1 1 NPS NPS -1 0 Swissprot and PISA say monomer 1cwo PROBNOT 1 1 NPS NPS 9769217 9769217 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 1cwq_1 YES 6 3 C3 C3 10949308 14532280 SP says trimer -- Duplicated chains - automatic transfer from 1vjm 1cwu NO 4 4 D2 D2 10521472 10521472 paper and SP say tetramer -- Annotation transfered from 1eno 1cx2_1 NO 2 2 C2 C2 8967954 10811226 - automatic transfer from 1cvu 1cx2_2 NO 2 2 C2 C2 8967954 10811226 - automatic transfer from 1cvu 1cx6 NO 1 1 NPS NPS 10556025 10556025 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1cx7 NO 1 1 NPS NPS 10666571 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1cx9 NO 4 4 C2 C2 10504236 10504236 Paper says a2b2 -- Annotation transfered from 2wsy 1cxa PROBNOT 1 1 NPS NPS 15299423 0 1cxc PROBNOT 1 1 NPS NPS 15299423 0 - automatic transfer from 1cxa 1cxe NO 1 1 NPS NPS 7493956 7493956 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1cxf NO 1 1 NPS NPS 7493956 7493956 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1cxh NO 1 1 NPS NPS 7493956 7493956 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1cxi NO 1 1 NPS NPS 7493956 7493956 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1cxk NO 1 1 NPS NPS 10331869 10331869 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1cxl NO 1 1 NPS NPS 10331869 10331869 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1cxq NO 2 2 C2 C2 10521258 10521258 Interface is conserved with 1itg even though seq sim is ~35% so I believe this interface is functionally relevant (plus it is known to oligomerize). - very interesting -- Annotation transfered from 1cxu 1cxu NO 2 2 C2 C2 10521258 10521258 Interface is conserved with 1itg even though seq sim is ~35% so I believe this interface is functionally relevant (plus it is known to oligomerize). - very interesting 1cy0 PROBNOT 1 1 NPS NPS 10504732 10504732 SP says monomer -- Annotation transfered from 1mw8 1cy1 PROBNOT 1 1 NPS NPS 10504732 10504732 SP says monomer -- Annotation transfered from 1mw8 1cy2 PROBNOT 1 1 NPS NPS 10504732 10504732 SP says monomer -- Annotation transfered from 1mw8 1cy4 PROBNOT 1 1 NPS NPS 10504732 10504732 SP says monomer -- Annotation transfered from 1mw8 1cy6 PROBNOT 1 1 NPS NPS 10504732 10504732 SP says monomer -- Annotation transfered from 1mw8 1cy7 PROBNOT 1 1 NPS NPS 10504732 10504732 SP says monomer -- Annotation transfered from 1mw8 1cy8 PROBNOT 1 1 NPS NPS 10504732 10504732 SP says monomer -- Annotation transfered from 1mw8 1cy9 PROBYES 2 1 C2 NPS 10504724 10504724 SP says monomer. -- Annotation transfered from 1cyy 1cyc_1 PROBNOT 1 1 NPS NPS 166072 0 - automatic transfer from 5cyt 1cyc_2 PROBNOT 1 1 NPS NPS 166072 0 - automatic transfer from 5cyt 1cyd PROBNOT 4 4 D2 D2 8805511 8805511 1cyf PROBNOT 1 1 NPS NPS 8547245 8547245 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1cyg PROBNOT 1 1 NPS NPS 0 0 SP says monomer 1cyi PROBNOT 1 1 NPS NPS 7623381 7623381 SP says monomer 1cyj PROBNOT 1 1 NPS NPS 7623381 7623381 SP says monomer -- Annotation transfered from 1cyi 1cyo PROBNOT 1 1 NPS NPS 15299727 0 Oligomeric state not mentioned - PISA says monomer -- Annotation transfered from 1lqx 1cyw PROBYES 2 1 C2 NPS 8618822 8618822 EcoCyc says monomer - PISA says tetramer 1cyx PROBNOT 1 1 NPS NPS 8618822 8618822 EcoCyc says monomer 1cyy PROBYES 2 1 C2 NPS 10504724 10504724 SP says monomer. 1cz3 NO 2 2 C2 C2 10731419 10731419 Dimer in Thermogota and monomer in others - interessting -- Annotation transfered from 1d1g 1cz7_2 NO 2 2 C2 C2 10574799 14532111 Dimeric ncd with neck linker - automatic transfer from 1n6m 1cz9 NO 2 2 C2 C2 10521258 10521258 Interface is conserved with 1itg even though seq sim is ~35% so I believe this interface is functionally relevant (plus it is known to oligomerize). - very interesting -- Annotation transfered from 1cxu 1cza PROBNOT 1 1 NPS NPS 10686099 10686099 SP says monomer -- Annotation transfered from 1dgk 1czb NO 2 2 C2 C2 10521258 10521258 Interface is conserved with 1itg even though seq sim is ~35% so I believe this interface is functionally relevant (plus it is known to oligomerize). - very interesting -- Annotation transfered from 1cxu 1czc NO 2 2 C2 C2 10731702 10731702 1cze NO 2 2 C2 C2 10731702 10731702 -- Annotation transfered from 1czc 1czh PROBNOT 1 1 NPS NPS 10610792 10610792 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins 1czj NO 2 2 C2 C2 8740362 8740362 Paper says dimer 1czk PROBNOT 1 1 NPS NPS 10610792 10610792 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1czh 1czl PROBNOT 1 1 NPS NPS 10610792 10610792 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1czh 1czm NO 1 1 NPS NPS 7932756 7932756 10529183 says monomer -- Annotation transfered from 1crm 1czn PROBNOT 1 1 NPS NPS 10610791 10610791 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1czh 1czo PROBNOT 1 1 NPS NPS 10610792 10610792 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1czh 1czp_1 PROBNOT 1 1 NPS NPS 10625442 9287153 Paper does not mention oligomer - similar proteins are monomeric - automatic transfer from 1j7c 1czp_2 PROBNOT 1 1 NPS NPS 10625442 9287153 Paper does not mention oligomer - similar proteins are monomeric - automatic transfer from 1j7c 1czr PROBNOT 1 1 NPS NPS 10610792 10610792 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1czh 1czu PROBNOT 1 1 NPS NPS 10610791 10610791 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1czh 1czy NO 3 3 C3 C3 10518213 10518213 Paper says trimer - interface conserved with 1kzz (55%) 1czz NO 3 3 C3 C3 10518213 10518213 Paper says trimer - interface conserved with 1kzz (55%) -- Annotation transfered from 1czy 1d00_1 NO 3 3 C3 C3 10518213 10518213 Paper says trimer - interface conserved with 1kzz (55%) - automatic transfer from 1czy 1d00_2 NO 3 3 C3 C3 10518213 10518213 Paper says trimer - interface conserved with 1kzz (55%) - automatic transfer from 1czy 1d00_3 NO 3 3 C3 C3 10518213 10518213 Paper says trimer - interface conserved with 1kzz (55%) - automatic transfer from 1czy 1d00_4 NO 3 3 C3 C3 10518213 10518213 Paper says trimer - interface conserved with 1kzz (55%) - automatic transfer from 1czy 1d01_1 NO 3 3 C3 C3 10518213 10518213 Paper says trimer - interface conserved with 1kzz (55%) - automatic transfer from 1czy 1d01_2 NO 3 3 C3 C3 10518213 10518213 Paper says trimer - interface conserved with 1kzz (55%) - automatic transfer from 1czy 1d03 PROBNOT 1 1 NPS NPS 10610791 10610791 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1czh 1d04 PROBNOT 1 1 NPS NPS 10610792 10610792 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1czh 1d07 NO 1 1 NPS NPS 11087355 11087355 SP says monomer -- Annotation transfered from 1g42 1d09 NO 12 12 D3 D3 10651286 10651286 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1d0a_1 NO 3 3 C3 C3 10518213 10518213 Paper says trimer - interface conserved with 1kzz (55%) - automatic transfer from 1czy 1d0a_2 NO 3 3 C3 C3 10518213 10518213 Paper says trimer - interface conserved with 1kzz (55%) - automatic transfer from 1czy 1d0c NO 2 2 C2 C2 11695891 11695891 Clear dimer -- Annotation transfered from 1fol 1d0e PROBYES 2 1 C2 NPS 10669612 9545316 1d0i NO 12 12 Tetr Tetr 11937054 11937054 Interface geometry conserved with 1h0s (43%) -- Annotation transfered from 1gu0 1d0j_1 NO 3 3 C3 C3 10518213 10518213 Paper says trimer - interface conserved with 1kzz (55%) - automatic transfer from 1czy 1d0j_2 NO 3 3 C3 C3 10518213 10518213 Paper says trimer - interface conserved with 1kzz (55%) - automatic transfer from 1czy 1d0o NO 2 2 C2 C2 11695891 11695891 Clear dimer -- Annotation transfered from 1fol 1d0q PROBYES 2 1 NS NPS 10745010 10745010 Paper implies monomer 1d1g NO 2 2 C2 C2 10731419 10731419 Dimer in Thermogota and monomer in others - interessting 1d1j PROBYES 4 1 D2 NPS 10600384 10600384 10214957 says: Mammalians have two profilin isoforms, profilin I and II. Both form a 1:1 complex with G-actin and have a similar Kd value of approximately 0.5 uM - 9034331 says: At micromolar concentrations, profilin II dimerizes upon binding to proline-rich peptides. Circular dichroism measurements of profilin II reveal a significant conformational change in this protein upon binding of the peptide. (But no peptide here) 1d1l YES 2 2 C2 C2 10686105 10686105 Paper says dimer but the wrong one is found here (cf paper) 1d1m YES 2 1 C2 NPS 10686105 10686105 Normally forms a dimer but engineered to form a monomer 1d1s YES 4 2 NS C2 10631979 10631979 -- Annotation transfered from 1d1t 1d1t YES 4 2 NS C2 10631979 10631979 1d1u NO 1 1 NPS NPS 10957631 10957631 Active as a monomer - Although HIV RT is active as a dimer (see ref) -- Annotation transfered from 1rw3 1d1v NO 2 2 C2 C2 11331290 11331290 Clear dimer -- Annotation transfered from 1fol 1d1w NO 2 2 C2 C2 11051558 11051558 Clear dimer -- Annotation transfered from 1fol 1d1x NO 2 2 C2 C2 11331290 11331290 Clear dimer -- Annotation transfered from 1fol 1d1y NO 2 2 C2 C2 11331290 11331290 Clear dimer -- Annotation transfered from 1fol 1d1z PROBYES 4 1 NS NPS 10549287 10549287 1d2c YES 2 4 C2 D2 10756111 10756111 Paper says tetramer -- Annotation transfered from 1d2g 1d2e PROBYES 4 1 NS NPS 10715211 9838020 EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa. 1d2f NO 2 2 C2 C2 10698925 10698925 1d2g YES 2 4 C2 D2 10756111 10756111 Paper says tetramer 1d2h NO 4 4 D2 D2 10756111 10756111 Paper says tetramer 1d2k PROBNOT 1 1 NPS NPS 10752616 10752616 Paper says nothing about oligomeric state, PISA says monomer 1d2n NO 6 6 C6 C6 9727495 9727495 Paper says hexamer -- Annotation transfered from 1nsf 1d2q YES 1 3 NPS C3 10485660 10485660 10651627 says trimer 1d2t NO 6 6 D3 D3 10835340 10835340 BU changed since last release and is now corrected - Paper says: The enzyme is a 150 kDa homohexamer. 1d2w NO 1 1 NPS NPS 10666571 10556025 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1d2y NO 1 1 NPS NPS 10666571 10556025 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1d3a NO 4 4 D2 D2 10653643 10653643 Paper says tetramer -- Annotation transfered from 2hlp 1d3b_1 PROBNOT 2 2 NS NS 10025403 10025403 Interface conserved with 1b34 (30% id), and more generally with lsm proteins -- Annotation transfered from 1d3b_6 1d3b_2 PROBNOT 2 2 NS NS 10025403 10025403 Interface conserved with 1b34 (30% id), and more generally with lsm proteins -- Annotation transfered from 1d3b_6 1d3b_3 PROBNOT 2 2 NS NS 10025403 10025403 Interface conserved with 1b34 (30% id), and more generally with lsm proteins -- Annotation transfered from 1d3b_6 1d3b_4 PROBNOT 2 2 NS NS 10025403 10025403 Interface conserved with 1b34 (30% id), and more generally with lsm proteins -- Annotation transfered from 1d3b_6 1d3b_5 PROBNOT 2 2 NS NS 10025403 10025403 Interface conserved with 1b34 (30% id), and more generally with lsm proteins -- Annotation transfered from 1d3b_6 1d3b_6 PROBNOT 2 2 NS NS 10025403 10025403 Interface conserved with 1b34 (30% id), and more generally with lsm proteins 1d3c NO 1 1 NPS NPS 10574960 10574960 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1d3f NO 1 1 NPS NPS 10666571 10556025 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1d3j NO 1 1 NPS NPS 10666571 10556025 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1d3l PROBNOT 1 1 NPS NPS 10562537 10562537 7608533 shows that equilibrium exists but shifted towards dimeric form. 1d3m NO 1 1 NPS NPS 10666571 10556025 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1d3n NO 1 1 NPS NPS 10666571 10556025 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1d3v_1 NO 3 3 C3 C3 10542097 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automatic transfer from 1hqx 1d3v_2 NO 3 3 C3 C3 10542097 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automatic transfer from 1hqx 1d3w NO 1 1 NPS NPS 10866206 10866206 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1d4a_1 NO 2 2 C2 C2 10706635 11587640 BU changed since last release and is now corrected - - automatic transfer from 1h66_2 1d4a_2 NO 2 2 C2 C2 10706635 11587640 BU changed since last release and is now corrected - - automatic transfer from 1h66_2 1d4c_1 PROBNOT 1 1 NPS NPS 10581551 10581551 Paper implies monomer - PISA says monomer - automatic transfer from 1d4e 1d4c_2 PROBNOT 1 1 NPS NPS 10581551 10581551 Paper implies monomer - PISA says monomer - automatic transfer from 1d4e 1d4c_3 PROBNOT 1 1 NPS NPS 10581551 10581551 Paper implies monomer - PISA says monomer - automatic transfer from 1d4e 1d4c_4 PROBNOT 1 1 NPS NPS 10581551 10581551 Paper implies monomer - PISA says monomer - automatic transfer from 1d4e 1d4d PROBNOT 1 1 NPS NPS 10581551 10581551 Paper implies monomer - PISA says monomer -- Annotation transfered from 1d4e 1d4e PROBNOT 1 1 NPS NPS 10581551 10581551 Paper implies monomer - PISA says monomer 1d4f NO 4 4 D2 D2 10913437 10913437 SP says tetramer, interface geometry conserved among rat and human. -- Annotation transfered from 1b3r 1d4h NO 2 2 C2 C2 12694187 12694187 -- Annotation transfered from 1ajx 1d4i NO 2 2 C2 C2 12694187 12694187 -- Annotation transfered from 1ajx 1d4j NO 2 2 C2 C2 12694187 12694187 -- Annotation transfered from 1ajx 1d4k NO 2 2 C2 C2 11000004 11000004 -- Annotation transfered from 1ajx 1d4l NO 2 2 C2 C2 11000004 11000004 -- Annotation transfered from 1ajx 1d4s NO 2 2 C2 C2 8893827 8893827 -- Annotation transfered from 1ajx 1d4t PROBNOT 1 1 NPS NPS 10549287 10549287 1d4w PROBYES 2 1 NS NPS 10549287 10549287 BU changed since last release and is now incorrect - 1d4y NO 2 2 C2 C2 8893827 8893827 -- Annotation transfered from 1ajx 1d4z NO 1 1 NPS NPS 10748173 10748173 CheY is a Mr 14,000 monomeric protein -- Annotation transfered from 1chn 1d5c PROBNOT 1 1 NPS NPS 10944329 10944329 Paper implies monomer: The Rab proteins are a large family of monomeric Ras-related GTPases 1d5f NA 3 3 C3 C3 10558980 10558980 Paper says nothing but it seems this is just a fragment --> ask 1d5j_1 PROBNOT 1 1 NPS NPS 10579818 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1d5j_2 PROBNOT 1 1 NPS NPS 10579818 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1d5n_1 NO 2 2 C2 C2 10686094 11294629 PAper, SP say dimer - automatic transfer from 1i0h 1d5n_2 NO 2 2 C2 C2 10686094 11294629 PAper, SP say dimer - automatic transfer from 1i0h 1d6f NO 2 2 C2 C2 10653632 0 1d6h NO 2 2 C2 C2 10653632 10653632 -- Annotation transfered from 1d6f 1d6i YES 4 2 C2 C2 10653632 10653632 Bad reconstruction 1d6m PROBNOT 1 1 NPS NPS 10574789 10574789 EcoCyc says monomer -- Annotation transfered from 1i7d 1d6n YES 2 4 C2 D2 10338013 10338013 Paper says tetramer 1d6o_1 PROBNOT 1 1 NPS NPS 10656803 10425089 BU changed since last release and is now corrected - - automaticaly inferred from 1qpl 1d6o_2 PROBNOT 1 1 NPS NPS 10656803 10425089 BU changed since last release and is now corrected - - automaticaly inferred from 1qpl 1d6p NO 1 1 NPS NPS 10630988 10630988 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1d6q NO 1 1 NPS NPS 10630988 10630988 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1d6s NO 2 2 C2 C2 10452898 10452898 Paper says: O-Acetylserine sulfhydrylase (EC 4.2.99.8) is a homodimeric pyridoxal 5′-phosphate (PLP)-dependent enzyme with a subunit molecular mass of 34,450 [Byrne et al 1988]. 1d6w PROBNOT 1 1 NPS NPS 10713516 10713516 -- Annotation transfered from 1doj 1d7e PROBNOT 1 1 NPS NPS 10739248 0 SP says monomer -- Annotation transfered from 1s1z 1d7f PROBYES 2 1 C2 NPS 10679895 10679895 Cyclodextrin - glycosyltransferases are monomeric, paper implies that this one is, SP and PISA too. 1d7h_1 PROBNOT 1 1 NPS NPS 10656803 10425089 BU changed since last release and is now corrected - - automaticaly inferred from 1qpl 1d7h_2 PROBNOT 1 1 NPS NPS 10656803 10425089 BU changed since last release and is now corrected - - automaticaly inferred from 1qpl 1d7i_1 PROBNOT 1 1 NPS NPS 10656803 10425089 BU changed since last release and is now corrected - - automaticaly inferred from 1qpl 1d7i_2 PROBNOT 1 1 NPS NPS 10656803 10425089 BU changed since last release and is now corrected - - automaticaly inferred from 1qpl 1d7j_1 PROBNOT 1 1 NPS NPS 10656803 10425089 BU changed since last release and is now corrected - - automaticaly inferred from 1qpl 1d7j_2 PROBNOT 1 1 NPS NPS 10656803 10425089 BU changed since last release and is now corrected - - automaticaly inferred from 1qpl 1d7l YES 1 2 NPS C2 10600126 10600126 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 1cc6 1d7o NO 4 4 D2 D2 10610777 10610777 paper and SP say tetramer -- Annotation transfered from 1eno 1d7r NO 4 4 D2 D2 10556038 10556038 Paper says tetramer -- Annotation transfered from 1dge 1d7s NO 4 4 D2 D2 10556038 10556038 Paper says tetramer -- Annotation transfered from 1dge 1d7u NO 4 4 D2 D2 10556038 10556038 Paper says tetramer -- Annotation transfered from 1dge 1d7v NO 4 4 D2 D2 10556038 10556038 Paper says tetramer -- Annotation transfered from 1dge 1d7x PROBYES 2 1 NS NPS 10639284 10639284 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme -- Annotation transfered from 1b3d 1d7y PROBNOT 2 2 C2 C2 11090282 11090282 They observe that it forms a dimer in solution but they cannot say which crystal contact is one forming the dimer - 1gv4 which is < 30% identical establishes a contact with exactly the same orientation so it is probably relevant -- very interesting, good example for conservation of interface 1d8a NO 4 4 D2 D2 10201369 10201369 -- Annotation transfered from 1c14 1d8f_1 PROBNOT 1 1 NPS NPS 10669564 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1d8f_2 PROBNOT 1 1 NPS NPS 10669564 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1d8m_1 PROBNOT 1 1 NPS NPS 11327577 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1d8m_2 PROBNOT 1 1 NPS NPS 11327577 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1d8t_1 PROBNOT 1 1 NPS NPS 10625477 9838020 BU changed since last release and is now corrected - EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa. - automaticaly inferred from 1dg1 1d8t_2 PROBNOT 1 1 NPS NPS 10625477 9838020 BU changed since last release and is now corrected - EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa. - automaticaly inferred from 1dg1 1d8u NA 2 2 C2 C2 10986467 10986467 The paper is not sure about the biological relevance of the dimer. -- paper does interresting comparison of the QS states though, potentially interesting for an evolution study. 1d9c NO 2 2 C2 C2 10666622 10666622 Native IFN-[gamma] exists as a homodimer. 1d9e NO 4 4 D2 D2 10734095 10734095 paper says homotetramer 1d9g NO 2 2 C2 C2 10666622 10666622 Native IFN-[gamma] exists as a homodimer. -- Annotation transfered from 1d9c 1d9i PROBNOT 1 1 NPS NPS 10713516 10713516 -- Annotation transfered from 1doj 1d9q NO 4 4 D2 D2 10581254 10581254 1d9u_1 PROBNOT 1 1 NPS NPS 11341831 9514719 BU changed since last release and is now corrected - No oligo mentionned - automaticaly inferred from 1am7 1d9u_2 PROBNOT 1 1 NPS NPS 11341831 9514719 BU changed since last release and is now corrected - No oligo mentionned - automaticaly inferred from 1am7 1d9v PROBNOT 1 1 NPS NPS 11747438 11747438 1d9w NO 1 1 NPS NPS 0 0 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1daa NO 2 2 C2 C2 7626635 7626635 Homodimer -- Annotation transfered from 2daa 1dad NO 2 2 C2 C2 7669756 7669756 Active form is a homodimer -- Annotation transfered from 1a82 1dae NO 2 2 C2 C2 7669756 7669756 Active form is a homodimer -- Annotation transfered from 1a82 1daf NO 2 2 C2 C2 7669756 7669756 Active form is a homodimer -- Annotation transfered from 1a82 1dag NO 2 2 C2 C2 7669756 7669756 Active form is a homodimer -- Annotation transfered from 1a82 1dah NO 2 2 C2 C2 7669756 7669756 Active form is a homodimer -- Annotation transfered from 1a82 1dai NO 2 2 C2 C2 7669756 7669756 Active form is a homodimer -- Annotation transfered from 1a82 1daj PROBNOT 1 1 NPS NPS 15299851 0 PISA also says monomer - Human is monomeric so I guess it should be - Only Thermogota seems to be dimeric -- Annotation transfered from 1cd2 1dak NO 2 2 C2 C2 9576910 9576910 Active form is a homodimer -- Annotation transfered from 1a82 1dam NO 2 2 C2 C2 9865950 9865950 Active form is a homodimer -- Annotation transfered from 1a82 1dap NO 2 2 C2 C2 8885833 8885833 Paper says dimer -- Annotation transfered from 2dap 1dat NO 24 24 Octa Octa -1 0 Interface geometry conserved with 1lb3 (80%) -- Annotation transfered from 1ies 1daw NO 1 1 NPS NPS 10581548 10581548 Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. -- Annotation transfered from 1jam 1day NO 1 1 NPS NPS 10581548 10581548 Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. -- Annotation transfered from 1jam 1daz NO 2 2 C2 C2 10429209 10429209 -- Annotation transfered from 1ajx 1db1 PROBNOT 1 1 NPS NPS 10678179 10678179 paper says nothing, PISA says monomer -- Annotation transfered from 1ie9 1db2 PROBYES 2 1 NS NPS 10731421 10731421 Paper says: The dimerisation mode seen here represents still another possibility for serpin polymerisation and is a further indicator for the propensity for β-structure formation of the RCL. - this family is very versatile -- THIS FAMILY IS A BIG SHIT 1db3 NO 2 2 C2 C2 10673432 10673432 Paper says dimer - PISA says hexamer - interesting if PISA not wrong - good to point out the graph advantage (I saw that the interf is small) 1db4 NO 1 1 NPS NPS 7664108 7664108 Human PLA predominantly exists as a monomer -- Annotation transfered from 1kqu 1db5 NO 1 1 NPS NPS 7664108 7664108 Human PLA predominantly exists as a monomer -- Annotation transfered from 1kqu 1dbf NO 3 3 C3 C3 10818343 8046752 Interface conserved with 1jd1 (0% id) -- Annotation transfered from 1com_1 1dbn PROBNOT 2 2 C2 C2 10747930 10747930 It seems that a dimer is found in solution but they have no idea which one. 1dbp NO 1 1 NPS NPS 8157648 8157648 ribose ABC transporter, subunit B - monomer according to EcoCyc -- Annotation transfered from 1drj 1dbq NO 2 2 C2 C2 7553867 7553867 EcoCyc says homodimer -- Annotation transfered from 1jhz 1dbr NO 4 4 D2 D2 8836106 8836106 Teramer, interface conserved down to 40% (1hmp) -- Annotation transfered from 1qk3 1dbs NO 2 2 C2 C2 7881906 7881906 Active form is a homodimer -- Annotation transfered from 1a82 1dbv NO 4 4 D2 D2 9175858 9175858 SP says homotetramer - papers too -- Annotation transfered from 1npt 1dbz NO 4 4 D2 D2 10581254 10581254 -- Annotation transfered from 1d9q 1dc3 YES 2 4 C2 D2 10978154 10978154 Tetramer in paper 1dc4 YES 2 4 C2 D2 10978154 10978154 1dc5 YES 2 4 C2 D2 10978154 10978154 Tetramer in paper 1dc6 YES 2 4 C2 D2 10978154 10978154 Tetramer in paper 1dc9 NO 1 1 NPS NPS 10692339 10692339 Paper says: large quantities of the native, monomeric protein can be produced in, and readily purified, from Escherichia coli. -- Annotation transfered from 1icm 1dca PROBNOT 1 1 NPS NPS 8399159 8399159 9000633 says monomeric -- Annotation transfered from 1uga 1dcb PROBNOT 1 1 NPS NPS 8399159 8399159 9000633 says monomeric -- Annotation transfered from 1uga 1dcc PROBNOT 1 1 NPS NPS 7664080 7664080 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1dcf NO 2 2 C2 C2 10647185 10647185 Paper says homodimer - general remark: this family is good to illustrate oligomeric states within a SF - interesting 1dci NO 6 6 D3 D3 9739087 9739087 1dcl NO 2 2 C2 C2 2515285 2515285 -- Annotation transfered from 1a8j 1dcn NO 4 4 D2 D2 10029536 15320872 Interface geometry conserved with 1fur (23%) - automatic transfer from 1tjw 1dcs PROBNOT 3 3 C3 C3 9723623 9723623 this suggests that the trimeric structure of the apoenzyme found in the crystal might have some functional significance, for example in the protection of the C-terminal arm (rich in lysines and arginines) against proteases in the apo- or resting forms of DAOCS. However, DAOCS dissociates into monomers in the presence of Fe(II) and 2-oxoglutarate. -- Annotation transfered from 1uog 1dcu NO 4 4 D2 D2 10581254 10581254 -- Annotation transfered from 1d9q 1dcy NO 1 1 NPS NPS 7664108 7664108 Human PLA predominantly exists as a monomer -- Annotation transfered from 1kqu 1dd1 NO 3 3 C3 C3 10647180 10647180 Interface geometry conserved with 1khx (42%) 1dd3_1 PROBNOT 2 2 C2 C2 10637222 10637222 Paper says a2b2 but b2 is a peptide of length < 22aa. So it is just a2 here. 1dd6_1 PROBNOT 1 1 NPS NPS 10757977 10757977 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Paper says nothing - PISA implies monomer - automaticaly inferred from 1ddk 1dd6_2 PROBNOT 1 1 NPS NPS 10757977 10757977 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Paper says nothing - PISA implies monomer - automaticaly inferred from 1ddk 1dd7 YES 2 1 NS NPS 10677491 10677491 Dimerization inhibited by small molecule -- very very interesting example 1ddj_1 PROBNOT 1 1 NPS NPS 10656799 10460175 BU changed since last release and is now corrected - Paper implies monomer although no clear evidence is given - automaticaly inferred from 1qrz 1ddj_2 PROBNOT 1 1 NPS NPS 10656799 10460175 BU changed since last release and is now corrected - Paper implies monomer although no clear evidence is given - automaticaly inferred from 1qrz 1ddj_3 PROBNOT 1 1 NPS NPS 10656799 10460175 BU changed since last release and is now corrected - Paper implies monomer although no clear evidence is given - automaticaly inferred from 1qrz 1ddj_4 PROBNOT 1 1 NPS NPS 10656799 10460175 BU changed since last release and is now corrected - Paper implies monomer although no clear evidence is given - automaticaly inferred from 1qrz 1ddk YES 4 1 D2 NPS 10757977 10757977 BU changed since last release and is now incorrect - Paper says nothing - PISA implies monomer 1ddn PROBYES 4 2 C2 C2 9697776 7568230 BU changed since last release and is now incorrect - Interface geometry conserved down to 30% with 1on1 - automaticaly inferred from 1dpr 1ddr PROBYES 2 1 C2 NPS 9260285 0 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1dds 1dds PROBYES 2 1 C2 NPS 9260285 0 ECOcyc says monomer - PISA says dimer 1ddu NO 2 2 C2 C2 9687366 9687366 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1ddv NO 1 1 NPS NPS 10798399 10798399 We also confirmed that CRH1 formed a monomer structure in solution by analytical centrifuge measurements as well as the small-angle X-ray scattering (SAXS) method, while the crystal structure showed intermolecular interactions with the neighbouring molecules in the crystal lattice. -- Annotation transfered from 1i2h 1ddw NO 1 1 NPS NPS 10798399 10798399 We also confirmed that CRH1 formed a monomer structure in solution by analytical centrifuge measurements as well as the small-angle X-ray scattering (SAXS) method, while the crystal structure showed intermolecular interactions with the neighbouring molecules in the crystal lattice. -- Annotation transfered from 1i2h 1ddx_1 NO 2 2 C2 C2 10811226 10811226 - automatic transfer from 1cvu 1ddx_2 NO 2 2 C2 C2 10811226 10811226 - automatic transfer from 1cvu 1dea NO 6 6 D3 D3 8747459 8747459 SP and EcoCyc say hexamer. -- Annotation transfered from 1cd5 1ded PROBYES 2 1 C2 NPS 10731709 10731709 Cyclodextrin - glycosyltransferases are monomeric, paper implies that this one is, SP and PISA too. -- Annotation transfered from 1d7f 1deg PROBNOT 1 1 NPS NPS 8341712 0 -- Annotation transfered from 3cln 1deh NO 2 2 C2 C2 8663387 8663387 Dimer of identical or non-identical chains of three types - gene dup - interesting -- Annotation transfered from 1hdx 1df1_1 PROBYES 2 1 C2 NPS 10562539 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1df1_2 PROBYES 2 1 C2 NPS 10562539 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1df7 PROBNOT 1 1 NPS NPS 10623528 10623528 1df8 NO 4 4 D2 D2 10850797 10850797 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1dfa PROBNOT 1 1 NPS NPS 10644733 10601013 BU changed since last release and is now corrected - From the paper it seems to be a monomer. - automaticaly inferred from 1ef0 1dff NO 1 1 NPS NPS 9374869 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues 1dfg NO 4 4 D2 D2 8953047 8953047 -- Annotation transfered from 1c14 1dfh NO 4 4 D2 D2 8953047 8953047 -- Annotation transfered from 1c14 1dfi NO 4 4 D2 D2 8953047 8953047 -- Annotation transfered from 1c14 1dfp PROBYES 2 1 C2 NPS 15299948 0 Infered from similar structures -- Annotation transfered from 1dsu 1dfv_1 PROBNOT 1 1 NPS NPS 10684642 10684642 BU changed since last release and is now corrected - Neutrophil gelatinase associated lipocalin (NGAL), a member of the lipocalin family, is released from neutrophil granules as a 25 kDa monomer, a 46 kDa disulfide-linked homodimer, and a disulfide-linked heterodimer with gelatinase B (matrix metalloproteinase 9) - this one is not linked by a S-S bond. - automaticaly inferred from 1qqs 1dfv_2 PROBNOT 1 1 NPS NPS 10684642 10684642 BU changed since last release and is now corrected - Neutrophil gelatinase associated lipocalin (NGAL), a member of the lipocalin family, is released from neutrophil granules as a 25 kDa monomer, a 46 kDa disulfide-linked homodimer, and a disulfide-linked heterodimer with gelatinase B (matrix metalloproteinase 9) - this one is not linked by a S-S bond. - automaticaly inferred from 1qqs 1dg1 YES 2 1 C2 NPS 8939740 9838020 EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa. 1dg5 PROBNOT 1 1 NPS NPS 10623528 10623528 -- Annotation transfered from 1df7 1dg6 NO 3 3 C3 C3 10651627 10651627 Paper says trimer 1dg7 PROBNOT 1 1 NPS NPS 10623528 10623528 -- Annotation transfered from 1df7 1dg8 PROBNOT 1 1 NPS NPS 10623528 10623528 -- Annotation transfered from 1df7 1dgb NO 4 4 D2 D2 10656833 10656833 Interface geometry conserved with 1mqf (52% id) -- Annotation transfered from 1dgg 1dgc NO 2 2 C2 C2 8377181 8377181 Paper says dimer -- Annotation transfered from 1zil 1dgd NO 4 4 D2 D2 7947767 7947767 Paper says tetramer -- Annotation transfered from 1dge 1dge NO 4 4 D2 D2 7947767 7947767 Paper says tetramer 1dgf NO 4 4 D2 D2 10656833 10656833 Interface geometry conserved with 1mqf (52% id) -- Annotation transfered from 1dgg 1dgg NO 4 4 D2 D2 10656833 10656833 Interface geometry conserved with 1mqf (52% id) 1dgh NO 4 4 D2 D2 10656833 10656833 Interface geometry conserved with 1mqf (52% id) - automatic transfer from 1dgg 1dgk PROBNOT 1 1 NPS NPS 10686099 10686099 SP says monomer 1dgl NO 4 4 D2 D2 9830028 11453695 Apparently this lectin exhibits a dimer-tetramer equilibrium that depends on pH. 1dhf PROBYES 2 1 C2 NPS 2248959 2248959 1dhi PROBYES 2 1 C2 NPS 8265622 8265622 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1dds 1dhj PROBYES 2 1 C2 NPS 8265622 8265622 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1dds 1dhp NO 4 4 D2 D2 7853400 7853400 Interface geometry conserved with 1fdy (25%) -- interesting QS evolution: interface geometry of these two proteins from e coli is conserved while the geometry with other proteins (closer in seq % id but from other organisms) is not. -- Annotation transfered from 1s5w 1dhr NO 2 2 C2 C2 1631094 1631094 SP says dimer 1dht NO 2 2 C2 C2 10625652 10625652 Paper says dimer -- Annotation transfered from 3dhe 1dhy YES 1 8 NPS D4 8636975 0 Interface geometry conserved with 1lgt (66%) 1di0 YES 5 10 C5 D5 10764570 14660615 Paper (14660615) says decamer 1di3 NO 1 1 NPS NPS 10913274 10913274 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1di4 NO 1 1 NPS NPS 10913274 10913274 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1di5 NO 1 1 NPS NPS 10913274 10913274 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1di6 NO 3 3 C3 C3 10636880 10636880 Interface geometry conserved with 1uux (38%) -- Annotation transfered from 1di7 1di7 NO 3 3 C3 C3 10636880 10636880 Interface geometry conserved with 1uux (38%) 1di8 NO 1 1 NPS NPS 10633045 10633045 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1di9 PROBNOT 1 1 NPS NPS 10633045 10633045 -- Annotation transfered from 1kv1 1dic PROBNOT 1 1 NPS NPS 9757085 9757085 1did NO 4 4 D2 D2 2304904 2304904 -- Annotation transfered from 1xlg 1die NO 4 4 D2 D2 2304904 2304904 -- Annotation transfered from 1xlg 1dif NO 2 2 C2 C2 8551523 8551523 -- Annotation transfered from 1ajx 1dik NO 2 2 C2 C2 8610096 8610096 Other dimers are wrong but this one is right - interface geometry conserved with 1h6z (50%) -- interesting pet example for a review, for showing that new homologous structures will help us uncover which interfaces are the right ones (here 1h6z allowed me to discriminate between the two possible interfaces). 1dir YES 4 2 NS C2 15299357 0 SP says dimer 1diy NO 2 2 C2 C2 10988074 10988074 BU changed since last release and is now corrected - 1dj1 PROBNOT 1 1 NPS NPS 10722697 10722697 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1dj5 PROBNOT 1 1 NPS NPS 10722697 10722697 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1dj9 YES 1 2 NPS C2 10642176 10642176 Paper describes a dimer and PISA finds it -- Annotation transfered from 1dje 1dja PROBYES 2 1 C2 NPS 8823158 8823158 Class A betalactamase are apparently monomeric in solution (said in paper) -- Annotation transfered from 1kgf 1djb PROBYES 2 1 C2 NPS 8823158 8823158 Class A betalactamase are apparently monomeric in solution (said in paper) -- Annotation transfered from 1kgf 1djc PROBYES 2 1 C2 NPS 8823158 8823158 Class A betalactamase are apparently monomeric in solution (said in paper) -- Annotation transfered from 1kgf 1dje YES 1 2 NPS C2 10642176 10642176 Paper describes a dimer and PISA finds it 1djt PROBYES 2 1 C2 NPS 0 15321715 No paper, other papers do not talk about a dimer, and paper put as a ref sasy that BMK M1 is monomeric 1dju NO 2 2 C2 C2 10671523 10671523 1dk4 NO 2 2 C2 C2 11062561 11062561 1dk8 ART 2 1 NS NPS 10811618 10811618 Paper says: Recently, Axin has also been shown to homodimerize - PISA also finds a dimer. However, the protein length here is 150 aa while the full length is 2800 aa. So I doubt that it s relevant and I ll consider it as a monomer and artifact. 1dka NO 4 4 D2 D2 8342040 8342040 Paper says tetramer -- Annotation transfered from 1dge 1dkj NO 1 1 NPS NPS 8880929 8880929 1dkk_1 NO 1 1 NPS NPS 8880929 8880929 - automatic transfer from 1dkj 1dkk_2 NO 1 1 NPS NPS 8880929 8880929 - automatic transfer from 1dkj 1dkr NO 6 6 D3 D3 10742175 10742175 1dks PROBYES 2 1 C2 NPS 7791211 7791211 Paper says: CksHs1 is a monomer -- Annotation transfered from 1dkt 1dkt PROBYES 2 1 C2 NPS 7791211 8805536 Paper says: CksHs1 is a monomer 1dku YES 2 6 C2 D3 10742175 10742175 1dkw YES 2 1 NS NPS 11151009 11151009 Paper says this is a monomeric variant 1dl3_1 PROBYES 1 2 NPS C2 10745009 9166771 BU changed since last release and is now incorrect - Interface conseved with 1v5x (42%) - automaticaly inferred from 1nsj 1dl3_2 PROBYES 1 2 NPS C2 10745009 9166771 BU changed since last release and is now incorrect - Interface conseved with 1v5x (42%) - automaticaly inferred from 1nsj 1dla_1 NO 1 1 NPS NPS 1734286 9195881 SwissProt an dPISA say monomer - automatic transfer from 1ah3 1dla_2 NO 1 1 NPS NPS 1734286 9195881 SwissProt an dPISA say monomer - automatic transfer from 1ah3 1dla_3 NO 1 1 NPS NPS 1734286 9195881 SwissProt an dPISA say monomer - automatic transfer from 1ah3 1dla_4 NO 1 1 NPS NPS 1734286 9195881 SwissProt an dPISA say monomer - automatic transfer from 1ah3 1dle PROBYES 2 1 NS NPS 10637221 10637221 SP says monomeric 1dlg_1 PROBNOT 1 1 NPS NPS 10694381 10823915 MurA crystallizes from PEG 20000 as a monomeric species. - automatic transfer from 1eyn 1dlg_2 PROBNOT 1 1 NPS NPS 10694381 10823915 MurA crystallizes from PEG 20000 as a monomeric species. - automatic transfer from 1eyn 1dlp NA 6 2 NS C2 10683433 10683433 Paper says: Arum maculatum agglutinin (AMA) is a dimeric lectin made up of two completely cleaved protomers which share approximately 40% sequence identity and probably exhibit a different specificity towards monosaccharides 1dlr PROBNOT 1 1 NPS NPS 7890613 7890613 -- Annotation transfered from 1s3u 1dls PROBNOT 1 1 NPS NPS 7890613 7890613 -- Annotation transfered from 1s3u 1dlu NO 4 4 D2 D2 10764581 10764581 Paper says tetramer -- Annotation transfered from 1dm3 1dlv NO 4 4 D2 D2 10764581 10764581 Paper says tetramer -- Annotation transfered from 1dm3 1dm1 NO 1 1 NPS NPS 10694477 10694477 Myoglobin is well known to be monomeric -- Annotation transfered from 2fal 1dm2 NO 1 1 NPS NPS 10662688 10662688 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1dm3 NO 4 4 D2 D2 10764581 10764581 Paper says tetramer 1dm5 NO 6 6 D3 D3 10704197 10704197 The annexin XII (ANXB12) crystal structure presented evidence that calcium mediates the formation of a hexamer through a novel intermolecular calcium-binding site - calcium induced hexamerization - very interesting! 1dm6 NO 2 2 C2 C2 11695891 11695891 Clear dimer -- Annotation transfered from 1fol 1dm7 NO 2 2 C2 C2 0 0 Clear dimer -- Annotation transfered from 1fol 1dm8 NO 2 2 C2 C2 0 0 Clear dimer -- Annotation transfered from 1fol 1dma YES 4 2 C2 C2 7568123 7568123 test 1dmb PROBNOT 1 1 NPS NPS 8399200 8399200 EcoCyc says monomer -- Annotation transfered from 1nl5 1dmi NO 2 2 C2 C2 0 0 Clear dimer -- Annotation transfered from 1fol 1dmj NO 2 2 C2 C2 11590164 11590164 Clear dimer -- Annotation transfered from 1fol 1dmk NO 2 2 C2 C2 11590164 11590164 Clear dimer -- Annotation transfered from 1fol 1dmm NO 2 2 C2 C2 10769113 10769113 -- Annotation transfered from 1e3v 1dmn NO 2 2 C2 C2 10769113 10769113 -- Annotation transfered from 1e3v 1dmp NO 2 2 C2 C2 8807858 8807858 -- Annotation transfered from 1ajx 1dmq NO 2 2 C2 C2 10769113 10769113 -- Annotation transfered from 1e3v 1dmw YES 1 2 NPS C2 10694386 10694386 They speak of the: dimeric catalytic domain (residues 117-424) - Even though the tetramerization helix is missing, it should still be a dimer. 1dmx YES 2 1 NS NPS 7479916 7479916 10529183 says monomer 1dmy_1 PROBNOT 1 1 NPS NPS 7479916 8794740 10529183 says monomer - automatic transfer from 1urt 1dmy_2 PROBNOT 1 1 NPS NPS 7479916 8794740 10529183 says monomer - automatic transfer from 1urt 1dn2 NO 2 2 C2 C2 10678837 10678837 1dna NO 2 2 C2 C2 9753479 9753479 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1dnc NO 2 2 C2 C2 9546215 9546215 Paper says dimer -- Annotation transfered from 5grt 1dnk NA 1 1 NPS NPS 1518054 1518054 1do0 NO 6 6 C6 C6 10693812 10693812 HSLU is the outer ring so it forms a hexamer (not a dodecamer) 1do1 NO 1 1 NPS NPS 10724176 10724176 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1do2_1 NO 6 6 C6 C6 10693812 10693812 HSLU is the outer ring so it forms a hexamer (not a dodecamer) - automatic transfer from 1do0 1do3 NO 1 1 NPS NPS 10724176 10724176 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1do4 NO 1 1 NPS NPS 10724176 10724176 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1do7 NO 1 1 NPS NPS 10724176 10724176 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1dob NO 2 2 C2 C2 7939628 7939628 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1doc NO 2 2 C2 C2 7939628 7939628 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1dod NO 2 2 C2 C2 7939628 7939628 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1doe NO 2 2 C2 C2 7939628 7939628 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1dof NO 4 4 D2 D2 10926519 10926519 Interface geometry conserved with 1fur (30%) 1doh NO 4 4 D2 D2 11342131 11342131 Said in paper that it is a tetramer -- Annotation transfered from 1g0o 1doi PROBYES 6 1 D3 NPS 8612076 8612076 Abstract does not mention oligomeric state, similar proteins are monomeric and PISA says monomer. 1doj PROBNOT 1 1 NPS NPS 11053836 11053836 1dok PROBNOT 2 2 C2 C2 8989326 8989326 In the abstract they speak about the two forms, but I dont know what is said in the paper. 1dol PROBNOT 1 1 NPS NPS 8989326 8989326 In the abstract they speak about the two forms, but I dont know what is said in the paper. 1dor NO 2 2 C2 C2 9032071 9032071 -- Annotation transfered from 1jub 1dos NO 2 2 C2 C2 8836102 8836102 -- Annotation transfered from 1b57 1dpb NO 24 24 Octa Octa 7703242 7703242 Interface geometry conserved with 1e2o (32%) -- Annotation transfered from 1ead 1dpc NO 24 24 Octa Octa 7703242 7703242 Interface geometry conserved with 1e2o (32%) -- Annotation transfered from 1ead 1dpd NO 24 24 Octa Octa 7703242 7703242 Interface geometry conserved with 1e2o (32%) -- Annotation transfered from 1ead 1dpf PROBNOT 1 1 NPS NPS 10748207 10748207 -- Annotation transfered from 1a2b 1dpg NO 2 2 C2 C2 7881907 7881907 -- Annotation transfered from 1e77 1dpo PROBNOT 1 1 NPS NPS 1881877 1881877 Trypsin is monomeric -- Annotation transfered from 2trm 1dpr NO 2 2 C2 C2 7568230 7568230 Interface geometry conserved down to 30% with 1on1 1dps NO 12 12 Tetr Tetr 9546221 9546221 Interface geometry conserved with 1o9r (55%) 1dpw NO 1 1 NPS NPS 10944331 10944331 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1dpx NO 1 1 NPS NPS 10944331 10944331 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1dpy NA 1 1 NPS NPS 11286555 11286555 Paper says nothing about oligomer - PISA says dimer 1dq0 NO 4 4 D2 D2 10748006 10748006 SP says tetramer -- Annotation transfered from 1cjp 1dq1 NO 4 4 D2 D2 10748006 10748006 SP says tetramer -- Annotation transfered from 1cjp 1dq2 NO 4 4 D2 D2 10748006 10748006 SP says tetramer -- Annotation transfered from 1cjp 1dq4 NO 4 4 D2 D2 10748006 10748006 SP says tetramer -- Annotation transfered from 1cjp 1dq5 NO 4 4 D2 D2 10748006 10748006 SP says tetramer -- Annotation transfered from 1cjp 1dq6 NO 4 4 D2 D2 10748006 10748006 SP says tetramer -- Annotation transfered from 1cjp 1dq8 NO 4 4 D2 D2 10698924 10698924 Paper says: The crystallographic analysis, as well as solution studies, reveals that the catalytic portion of human HMGR is a tetramer, suggesting a revised mechanism of sterol sensing by HMGR. 1dq9 NO 4 4 D2 D2 10698924 10698924 Paper says: The crystallographic analysis, as well as solution studies, reveals that the catalytic portion of human HMGR is a tetramer, suggesting a revised mechanism of sterol sensing by HMGR. -- Annotation transfered from 1dq8 1dqa NO 4 4 D2 D2 10698924 10698924 Paper says: The crystallographic analysis, as well as solution studies, reveals that the catalytic portion of human HMGR is a tetramer, suggesting a revised mechanism of sterol sensing by HMGR. -- Annotation transfered from 1dq8 1dqe PROBYES 2 1 NS NPS 10662696 10662696 1dqn NO 2 2 C2 C2 10841757 10841757 The dimer in Giardia is similar to those observed for the Trypanosoma cruzi HPRTase (10) and the Tritrochomonas foetus HGXPRTase (11). Although human and malarial HG(X)PRTases form tetramers in the crystal structure, the most extensive dimeric interfaces in these tetramers are similar to the dimer interfaces in Giardia GPRTase (7, 8). 1dqp NO 2 2 C2 C2 10841757 10841757 The dimer in Giardia is similar to those observed for the Trypanosoma cruzi HPRTase (10) and the Tritrochomonas foetus HGXPRTase (11). Although human and malarial HG(X)PRTases form tetramers in the crystal structure, the most extensive dimeric interfaces in these tetramers are similar to the dimer interfaces in Giardia GPRTase (7, 8). -- Annotation transfered from 1dqn 1dqr NO 2 2 C2 C2 10653639 10653639 -- Annotation transfered from 1iat 1dqs PROBNOT 2 2 C2 C2 9685163 9685163 Paper says dimer - Interface geometry conserved with 1ujn (38%) -- Annotation transfered from 1nvd 1dqu NO 4 4 D2 D2 10801489 10801489 Interface conserved with 1pym (30%) -- domain architecture has changed --> SCOP error?. This is a much bigger complex. 1dqy NO 1 1 NPS NPS 10655617 10655617 ag85C is a single-domain monomeric protein 1dqz YES 2 1 C2 NPS 10655617 10655617 ag85C is a single-domain monomeric protein 1dr1 NA 1 2 NPS C2 1510919 1510919 Not sure about the oligomeric state. PISA says dimer, but in Human it is clearly a monomer. That could be interessting -- Annotation transfered from 1dr7 1dr2 NA 1 2 NPS C2 8334118 8334118 Not sure about the oligomeric state. PISA says dimer, but in Human it is clearly a monomer. That could be interessting -- Annotation transfered from 1dr7 1dr3 NA 1 2 NPS C2 8334118 8334118 Not sure about the oligomeric state. PISA says dimer, but in Human it is clearly a monomer. That could be interessting -- Annotation transfered from 1dr7 1dr4 NA 1 2 NPS C2 0 0 Not sure about the oligomeric state. PISA says dimer, but in Human it is clearly a monomer. That could be interessting -- Annotation transfered from 1dr7 1dr5 NA 1 2 NPS C2 0 0 Not sure about the oligomeric state. PISA says dimer, but in Human it is clearly a monomer. That could be interessting -- Annotation transfered from 1dr7 1dr6 NA 1 2 NPS C2 0 0 Not sure about the oligomeric state. PISA says dimer, but in Human it is clearly a monomer. That could be interessting -- Annotation transfered from 1dr7 1dr7 NA 1 2 NPS C2 0 0 Not sure about the oligomeric state. PISA says dimer, but in Human it is clearly a monomer. That could be interessting 1dra PROBYES 2 1 C2 NPS 1998681 1998681 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1dds 1drb PROBYES 2 1 C2 NPS 1998681 1998681 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1dds 1dre PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1drf PROBNOT 1 1 NPS NPS 3383852 3383852 -- Annotation transfered from 1s3u 1drg NO 3 3 C3 C3 11601846 11601846 Paper says: To our knowledge, this is the first direct demonstration of quasi-equivalence in both the assembly and function of an oligomeric enzyme. -- very nice: C3 --> C4 transition at 99% des id! -- Annotation transfered from 1f44 1drh PROBNOT 1 1 NPS NPS 7873554 7873554 ECOcyc says monomer - PISA says dimer 1drj NO 1 1 NPS NPS 7982928 7982928 ribose ABC transporter, subunit B - monomer according to EcoCyc 1drk NO 1 1 NPS NPS 7982928 7982928 ribose ABC transporter, subunit B - monomer according to EcoCyc -- Annotation transfered from 1drj 1ds4 PROBNOT 1 1 NPS NPS 11170452 11170452 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1ds5_1 PROBYES 2 1 C2 NPS 10931203 11604527 BU changed since last release and is now incorrect - Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. - automaticaly inferred from 1jam 1ds5_2 PROBYES 2 1 C2 NPS 10931203 11604527 BU changed since last release and is now incorrect - Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. - automaticaly inferred from 1jam 1dsb NA 2 1 C2 NPS 8413591 10700276 It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant 1dse PROBNOT 1 1 NPS NPS 11170452 11170452 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1dsg PROBNOT 1 1 NPS NPS 11170452 11170452 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1dsl PROBNOT 1 1 NPS NPS 8605629 8605629 However, this domain truncated by just the C-terminal tyrosine forms a symmetric homodimer of domains in the crystal lattice. So there is a reason why both complexes adopt a different packing but whats happening in solution? 1dso PROBNOT 1 1 NPS NPS 11170452 11170452 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1dsp PROBNOT 1 1 NPS NPS 11170452 11170452 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1dss NO 4 4 D2 D2 10191140 10191140 SP says homotetramer - papers too -- Annotation transfered from 1szj 1dst PROBNOT 1 1 NPS NPS 7592653 9757085 - automatic transfer from 1dic 1dsu PROBYES 2 1 C2 NPS 8289289 8289289 Infered from similar structures 1dsx_1 NO 4 4 C4 C4 11007484 11007484 Interface geometry conserved with 3kvt (42%) - automatic transfer from 1qdv 1dsx_2 NO 4 4 C4 C4 11007484 11007484 Interface geometry conserved with 3kvt (42%) - automatic transfer from 1qdv 1dsy PROBNOT 1 1 NPS NPS 10562545 10562545 No oligomeric state discussed - PISA says monomer 1dt1 NO 1 1 NPS NPS 11152119 11152119 1dt3_1 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1dt3_2 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1dt5_1 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1dt5_2 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1dt5_3 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1dt5_4 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1dt5_5 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1dt5_6 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1dt5_7 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1dt5_8 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1dt6 PROBNOT 1 1 NPS NPS 10678174 10678174 11304120 says P450s are monomeric enzymes -- Annotation transfered from 1nr6 1dte_1 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1dte_2 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1dth PROBYES 2 1 C2 NPS 8610113 8610113 Papers say nothing and PISA says monomer 1dti NO 1 1 NPS NPS 11084036 11084036 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1dtl PROBNOT 1 1 NPS NPS 10792039 10792039 Close homologs are monomers and PISA says monomer 1dtm NO 1 1 NPS NPS 10813811 10813811 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1dtn NO 8 8 D4 D4 7893689 7893689 Interface geometry conserved with 1sjb (24%) -- Annotation transfered from 1mns 1dto NO 2 2 C2 C2 10693813 10693813 Paper says: The E2NT module forms a dimer both in the crystal and in solution. 1dts NO 2 2 C2 C2 8081756 9576910 Active form is a homodimer - automatic transfer from 1a82 1dtu NO 1 1 NPS NPS 10686101 10686101 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1dtx PROBNOT 1 1 NPS NPS 1373774 1373774 PISA says monomer 1dty NO 2 2 C2 C2 0 0 Paper says dimer -- Annotation transfered from 1mly 1du4_1 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1du4_2 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1du4_3 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1du4_4 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1du5 PROBYES 2 1 C2 NPS 8548448 0 Thaumatin-like Zeamatin is a 22 kDa protein isolated from corn 1dub NO 6 6 D3 D3 8895557 8895557 Everyone says hexamer! -- Annotation transfered from 2dub 1duc PROBNOT 3 3 C3 C3 9878436 9878436 Paper says: EIAV dUTPase is a homotrimer where each subunit folds into a twisted antiparallel beta-barrel with the N and C-terminal portions interacting with adjacent subunits. -- Annotation transfered from 1dun 1dug NO 2 2 C2 C2 10631982 10631982 -- Annotation transfered from 1bg5 1dui NO 1 1 NPS NPS -1 0 -- Annotation transfered from 1yja 1duk NO 1 1 NPS NPS 10813811 10813811 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1dun PROBNOT 3 3 C3 C3 9878436 9878436 Paper says: EIAV dUTPase is a homotrimer where each subunit folds into a twisted antiparallel beta-barrel with the N and C-terminal portions interacting with adjacent subunits. 1duo NO 1 1 NPS NPS 10813811 10813811 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1dur 1 1 NPS NPS 0 0 -- family remark: BAD BAD family. Poor info, many dimerization types that are condition dependant. interesting though. 1dut_1 PROBNOT 3 3 C3 C3 8976551 10957629 Paper says: The P63 crystal form contains independent trimers on the 63 screw and threefold axes. - automatic transfer from 1f7o 1dut_2 PROBNOT 3 3 C3 C3 8976551 10957629 Paper says: The P63 crystal form contains independent trimers on the 63 screw and threefold axes. - automatic transfer from 1f7o 1duv PROBNOT 3 3 C3 C3 10747936 10747936 Paper says trimer: Anabolic OTCase is the simplest form of the enzyme, comprising a single homotrimeric unit 1duw YES 1 2 NPS C2 11170457 11170457 Interface geometry conserved with 1ofw (85% id) 1dux PROBYES 2 1 C2 NPS 10742173 10742173 Papers from orthologous proteins say it is monomeric in solution (15591056) and this paper does not mentions a dimer. PISA also says monomer 1dv7 YES 2 2 NS C2 10681441 10681441 Interface geometry conserved with 1q6q (26%) 1dv8 NO 1 1 NPS NPS 10891274 10891274 Paper says: The electrophoretically pure protein was analysed with respect to its oligomeric state by analytical ultra-centrifugation. Sedimentation equilibrium analysis at different speeds showed it to be in a monomer / dimer equilibrium. 1dvb NO 2 2 C2 C2 10968622 10968622 -- Annotation transfered from 1lkm 1dvi NO 2 2 C2 C2 9228945 9228945 -- Annotation transfered from 1alv 1dvj_1 PROBYES 1 2 NPS C2 10681441 12011084 BU changed since last release and is now incorrect - SP says dimer - interface geometry conserved with 1q6q (26%) - automaticaly inferred from 1lor 1dvj_2 PROBYES 1 2 NPS C2 10681441 12011084 BU changed since last release and is now incorrect - SP says dimer - interface geometry conserved with 1q6q (26%) - automaticaly inferred from 1lor 1dvj_3 PROBYES 1 2 NPS C2 10681441 12011084 BU changed since last release and is now incorrect - SP says dimer - interface geometry conserved with 1q6q (26%) - automaticaly inferred from 1lor 1dvj_4 PROBYES 1 2 NPS C2 10681441 12011084 BU changed since last release and is now incorrect - SP says dimer - interface geometry conserved with 1q6q (26%) - automaticaly inferred from 1lor 1dvm_1 PROBNOT 1 1 NPS NPS 10913251 10913251 Paper says nothing - Family mostly monomeric - PISA says monomer - automatic transfer from 1dvn 1dvm_2 PROBNOT 1 1 NPS NPS 10913251 10913251 Paper says nothing - Family mostly monomeric - PISA says monomer - automatic transfer from 1dvn 1dvm_3 PROBNOT 1 1 NPS NPS 10913251 10913251 Paper says nothing - Family mostly monomeric - PISA says monomer - automatic transfer from 1dvn 1dvm_4 PROBNOT 1 1 NPS NPS 10913251 10913251 Paper says nothing - Family mostly monomeric - PISA says monomer - automatic transfer from 1dvn 1dvn PROBNOT 1 1 NPS NPS 10913251 10913251 Paper says nothing - Family mostly monomeric - PISA says monomer 1dvq NO 4 4 D2 D2 10742177 10742177 transthyretin is tetrameric -- Annotation transfered from 1fh2 1dvr PROBYES 2 1 C2 NPS 8594191 8594191 SP and PISA say monomer 1dvs NO 4 4 D2 D2 10742177 10742177 transthyretin is tetrameric -- Annotation transfered from 1fh2 1dvt NO 4 4 D2 D2 10742177 10742177 transthyretin is tetrameric -- Annotation transfered from 1fh2 1dvu NO 4 4 D2 D2 10742177 10742177 transthyretin is tetrameric -- Annotation transfered from 1fh2 1dvx NO 4 4 D2 D2 10742177 10742177 transthyretin is tetrameric -- Annotation transfered from 1fh2 1dvy NO 4 4 D2 D2 10742177 10742177 transthyretin is tetrameric -- Annotation transfered from 1fh2 1dvz NO 4 4 D2 D2 10742177 10742177 transthyretin is tetrameric -- Annotation transfered from 1fh2 1dw6 NO 2 2 C2 C2 10429209 10429209 -- Annotation transfered from 1ajx 1dwa NO 2 2 C2 C2 10713520 10713520 -- Annotation transfered from 1e70 1dwf NO 2 2 C2 C2 10713520 10713520 -- Annotation transfered from 1e70 1dwg NO 2 2 C2 C2 10713520 10713520 -- Annotation transfered from 1e70 1dwh NO 2 2 C2 C2 10713520 10713520 -- Annotation transfered from 1e70 1dwi NO 2 2 C2 C2 10713520 10713520 -- Annotation transfered from 1e70 1dwj NO 2 2 C2 C2 10713520 10713520 -- Annotation transfered from 1e70 1dwo PROBYES 4 4 C2 D2 11173464 9030531 BU changed since last release and is now incorrect - Reported as a homotetramer in this paper but it seems that an equilibrium exists. Also multiple oligomeric states exists in homologous enzymes - interesting case. 1dwp NA 4 4 C2 C2 0 0 Reported as a homotetramer in this paper but it seems that an equilibrium exists. Also multiple oligomeric states exists in homologous enzymes - interesting case. Because the tetramer has a C2 symmetry I find it very strange -- Annotation transfered from 1dwq 1dwq NA 2 4 C2 C2 11173464 9030531 BU changed since last release and is now incorrect - Reported as a homotetramer in this paper but it seems that an equilibrium exists. Also multiple oligomeric states exists in homologous enzymes - interesting case. Because the tetramer has a C2 symmetry I find it very strange 1dwr NO 1 1 NPS NPS 10706294 0 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1dws NO 1 1 NPS NPS 10706294 0 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1dwt NO 1 1 NPS NPS 10706294 0 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1dwv YES 2 2 C2 C2 10562538 10562538 Wrong reconstruction 1dww YES 2 2 C2 C2 10562538 10562538 Wrong reconstruction -- Annotation transfered from 1dwv 1dwx YES 2 2 C2 C2 10562538 10562538 Wrong reconstruction -- Annotation transfered from 1dwv 1dx4 YES 1 2 NPS C2 10892800 10892800 Paper SP and PISA say dimer. (disulfide bridged!) -- Annotation transfered from 1qo9 1dx6 PROBNOT 1 1 NPS NPS 10606746 10606746 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1dx9_1 PROBNOT 1 1 NPS NPS 10734100 8599758 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins - automatic transfer from 1ftg 1dx9_2 PROBNOT 1 1 NPS NPS 10734100 8599758 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins - automatic transfer from 1ftg 1dx9_3 PROBNOT 1 1 NPS NPS 10734100 8599758 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins - automatic transfer from 1ftg 1dx9_4 PROBNOT 1 1 NPS NPS 10734100 8599758 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins - automatic transfer from 1ftg 1dxc NO 1 1 NPS NPS 10681426 10681426 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1dxd NO 1 1 NPS NPS 10681426 10681426 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1dxh NO 12 12 Tetr Tetr 0 0 Interface geometry conserved with 1vlv (44%) -- Annotation transfered from 1ort 1dxi NO 4 4 D2 D2 15299450 0 -- Annotation transfered from 1s5m 1dxk NO 1 1 NPS NPS 10933508 10933508 -- Annotation transfered from 1bvt 1dxm PROBYES 2 1 C2 NPS 10806386 10806386 They do not speak about dimers and an experiment in the paper suggests that it is a monomer. 1dxo_1 NO 2 2 C2 C2 10706635 11587640 BU changed since last release and is now corrected - - automatic transfer from 1h66_2 1dxo_2 NO 2 2 C2 C2 10706635 11587640 BU changed since last release and is now corrected - - automatic transfer from 1h66_2 1dxx PROBYES 4 2 D2 C2 10801490 10801490 Infered from the paper (they do not speak about the tetramer, just about the dimer) 1dxy NO 2 2 C2 C2 9126843 9126843 Interface geometry conserved with 2nad (22%) 1dy3 PROBNOT 1 1 NPS NPS 10452528 10452528 EcoCyc & SP say monomer. -- Annotation transfered from 1eqm 1dy4 PROBNOT 1 1 NPS NPS 11114249 11114249 None of the papers speaks about a dimer - a dimer is found using PISA but visual inspection reveals a weak interface. -- Annotation transfered from 6cel 1dy5_1 PROBNOT 1 1 NPS NPS 10731423 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1dy5_2 PROBNOT 1 1 NPS NPS 10731423 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1dya NO 1 1 NPS NPS 8289284 8289284 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1dyb NO 1 1 NPS NPS 8289284 8289284 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1dyc NO 1 1 NPS NPS 8289284 8289284 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1dyd NO 1 1 NPS NPS 8289284 8289284 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1dye NO 1 1 NPS NPS 8289284 8289284 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1dyf NO 1 1 NPS NPS 8289284 8289284 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1dyg NO 1 1 NPS NPS 8289284 8289284 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1dyh PROBYES 2 1 C2 NPS 7873554 7873554 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1dds 1dyi PROBYES 2 1 C2 NPS 7873554 7873554 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1dds 1dyj PROBYES 2 1 C2 NPS 7873554 7873554 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1dds 1dym PROBNOT 1 1 NPS NPS 9761741 9761741 SP says monomer -- Annotation transfered from 1a39 1dyr PROBNOT 1 1 NPS NPS 7866743 10194348 PISA also says monomer - Human is monomeric so I guess it should be - Only Thermogota seems to be dimeric - automatic transfer from 1cd2 1dys NA 2 2 C2 C2 10794732 10794732 WT prot forms dimer but 100aa are missing - Are they involved in dimerization? - PISA says monomer --> send email 1dyt YES 2 1 C2 NPS 10903870 10903870 1dyw PROBYES 2 1 C2 NPS 10574961 10574961 Infered from inspection of the crystal structure. The contact does not seem very extensive. 1dyz NA 2 1 C2 NPS 10818345 10818345 No clear info found -- Annotation transfered from 1dz0 1dz0 NA 2 1 C2 NPS 10818345 10818345 No clear info found 1dz3 NO 2 2 C2 C2 10731426 10731426 Paper says dimer 1dz4_1 PROBNOT 1 1 NPS NPS 10698731 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1dz4_2 PROBNOT 1 1 NPS NPS 10698731 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1dz6_1 PROBNOT 1 1 NPS NPS 10698731 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1dz6_2 PROBNOT 1 1 NPS NPS 10698731 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1dz8_1 PROBNOT 1 1 NPS NPS 10698731 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1dz8_2 PROBNOT 1 1 NPS NPS 10698731 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1dz9_1 PROBNOT 1 1 NPS NPS 10698731 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1dz9_2 PROBNOT 1 1 NPS NPS 10698731 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1dza YES 2 1 NS NPS 11021969 11021969 Swissprot says it is a monomer. However, a domain swaped dimer also exists. 1dze NO 3 3 C3 C3 0 0 SP says trimer -- Annotation transfered from 2brd 1dzf YES 2 2 C2 C2 10841537 10841537 Paper says: Archaeal RPB5 homologues, on the other hand, lack this particular domain, and no evidence for homodimerization of subunit H from M. jannaschii has been found. Size exclusion column chromatography of the recombinant yRPB5 used for our crystallization trials similarly failed to provide support for any detectable tendency for yRPB5 to homodimerize under a number of different experimental conditions (R.O.J.W., unpublished observations). The intrinsically monomeric nature of yRPB5 is clearly confirmed by the arrangement of the molecules in the crystal lattice. 1dzg PROBNOT 2 2 C2 C2 10809774 10809774 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization -- Annotation transfered from 1jvq 1dzh PROBNOT 2 2 C2 C2 10809774 10809774 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization -- Annotation transfered from 1jvq 1dzi PROBNOT 1 1 NPS NPS 10778855 10778855 1dzj_1 NO 1 1 NPS NPS 10864504 11119644 Porcine OBP was believed for a long time to be a monomer under physiological conditions but there are recent data that support the existence of a monomer-dimer equilibrium. - automatic transfer from 1hqp 1dzj_2 NO 1 1 NPS NPS 10864504 11119644 Porcine OBP was believed for a long time to be a monomer under physiological conditions but there are recent data that support the existence of a monomer-dimer equilibrium. - automatic transfer from 1hqp 1dzk_1 NO 1 1 NPS NPS 10864504 11119644 Porcine OBP was believed for a long time to be a monomer under physiological conditions but there are recent data that support the existence of a monomer-dimer equilibrium. - automatic transfer from 1hqp 1dzk_2 NO 1 1 NPS NPS 10864504 11119644 Porcine OBP was believed for a long time to be a monomer under physiological conditions but there are recent data that support the existence of a monomer-dimer equilibrium. - automatic transfer from 1hqp 1dzm_1 NO 1 1 NPS NPS 10864504 11119644 Porcine OBP was believed for a long time to be a monomer under physiological conditions but there are recent data that support the existence of a monomer-dimer equilibrium. - automatic transfer from 1hqp 1dzm_2 NO 1 1 NPS NPS 10864504 11119644 Porcine OBP was believed for a long time to be a monomer under physiological conditions but there are recent data that support the existence of a monomer-dimer equilibrium. - automatic transfer from 1hqp 1dzn PROBYES 2 8 C2 D4 10809721 10809721 Paper says: Analytical gel filtration experiments showed that the His422 mutants are mainly in the octameric form with a small portion being present as a dimer. - dimer octamer equilibrium -- Annotation transfered from 1qlt 1dzp PROBYES 2 1 NS NPS 10864504 10864504 Porcine OBP was believed for a long time to be a monomer under physiological conditions but there are recent data that support the existence of a monomer-dimer equilibrium. - If a dimer that is probably not one with an open symmetry. -- Annotation transfered from 1e02 1dzq NO 4 4 D2 D2 10966800 10966800 -- Annotation transfered from 1qnw 1dzr NO 2 2 C2 C2 10802738 10802738 Interface geometry conserved with 1rtv (65%) 1dzt NO 2 2 C2 C2 10802738 10802738 Interface geometry conserved with 1rtv (65%) -- Annotation transfered from 1dzr 1dzu NO 4 4 C4 C4 10821675 10821675 -- Annotation transfered from 1e4a 1dzv NO 4 4 C4 C4 10821675 10821675 -- Annotation transfered from 1e4a 1dzw NO 4 4 C4 C4 10821675 10821675 -- Annotation transfered from 1e4a 1dzx NO 4 4 C4 C4 10821675 10821675 -- Annotation transfered from 1e4a 1dzy NO 4 4 C4 C4 10821675 10821675 -- Annotation transfered from 1e4a 1dzz NO 4 4 C4 C4 10821675 10821675 -- Annotation transfered from 1e4a 1e00_1 NO 1 1 NPS NPS 10864504 11119644 Porcine OBP was believed for a long time to be a monomer under physiological conditions but there are recent data that support the existence of a monomer-dimer equilibrium. - automatic transfer from 1hqp 1e00_2 NO 1 1 NPS NPS 10864504 11119644 Porcine OBP was believed for a long time to be a monomer under physiological conditions but there are recent data that support the existence of a monomer-dimer equilibrium. - automatic transfer from 1hqp 1e02 PROBYES 2 1 NS NPS 10864504 10864504 Porcine OBP was believed for a long time to be a monomer under physiological conditions but there are recent data that support the existence of a monomer-dimer equilibrium. - If a dimer that is probably not one with an open symmetry. 1e03 PROBNOT 2 2 C2 C2 9405673 9405673 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization -- Annotation transfered from 1jvq 1e04 PROBNOT 2 2 C2 C2 9067613 9067613 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization -- Annotation transfered from 1jvq 1e05 PROBNOT 2 2 C2 C2 9067613 9067613 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization -- Annotation transfered from 1jvq 1e06 PROBYES 2 1 NS NPS 10864504 10864504 Porcine OBP was believed for a long time to be a monomer under physiological conditions but there are recent data that support the existence of a monomer-dimer equilibrium. - If a dimer that is probably not one with an open symmetry. -- Annotation transfered from 1e02 1e0j_1 PROBYES 6 6 C6 NS 10892646 10535735 BU changed since last release and is now incorrect - Open ring - automaticaly inferred from 1cr0 1e0j_2 PROBYES 6 6 C6 NS 10892646 10535735 BU changed since last release and is now incorrect - Open ring - automaticaly inferred from 1cr0 1e0k_1 PROBYES 6 6 C6 NS 10892646 10535735 BU changed since last release and is now incorrect - Open ring - automaticaly inferred from 1cr0 1e0k_2 PROBYES 6 6 C6 NS 10892646 10535735 BU changed since last release and is now incorrect - Open ring - automaticaly inferred from 1cr0 1e0p_1 PROBNOT 3 3 C3 C3 10949307 14532280 BU changed since last release and is now corrected - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1e0p_2 PROBNOT 3 3 C3 C3 10949307 14532280 BU changed since last release and is now corrected - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1e0s PROBNOT 1 1 NPS NPS 10881192 10881192 PAper says nothing, PISA says monomer 1e0t NO 4 4 D2 D2 10751408 10751408 Interface geometry conserved with 1pkm (50%) -- Annotation transfered from 1pky 1e0u NO 4 4 D2 D2 10751408 10751408 Interface geometry conserved with 1pkm (50%) -- Annotation transfered from 1pky 1e0v PROBNOT 1 1 NPS NPS 10930426 10767281 Seems to be monomeric although there is no clear evidence -- Annotation transfered from 1v0k 1e0w PROBNOT 1 1 NPS NPS 10930426 10767281 Seems to be monomeric although there is no clear evidence -- Annotation transfered from 1v0k 1e0x_1 PROBNOT 1 1 NPS NPS 10930426 10767281 BU changed since last release and is now corrected - 1e0x_2 PROBNOT 1 1 NPS NPS 10930426 10767281 BU changed since last release and is now corrected - 1e0y PROBYES 2 8 C2 D4 10920192 0 Paper says: Analytical gel filtration experiments showed that the His422 mutants are mainly in the octameric form with a small portion being present as a dimer. - dimer octamer equilibrium -- Annotation transfered from 1qlt 1e12 NO 3 3 C3 C3 10827943 10827943 SP says trimer 1e1e_1 PROBYES 1 2 NPS C2 11171077 11706179 BU changed since last release and is now incorrect - Paper says: It was unexpected that the E401D as well as C205S and C211S mutations dramatically impaired the assembly of a catalysis-competent homodimer, suggesting novel links between the active site structure and dimer formation. -- Interesting: link between dimer formation and catalysis - automaticaly inferred from 1hxj 1e1e_2 PROBYES 1 2 NPS C2 11171077 11706179 BU changed since last release and is now incorrect - Paper says: It was unexpected that the E401D as well as C205S and C211S mutations dramatically impaired the assembly of a catalysis-competent homodimer, suggesting novel links between the active site structure and dimer formation. -- Interesting: link between dimer formation and catalysis - automaticaly inferred from 1hxj 1e1f_1 PROBYES 1 2 NPS C2 11171077 11706179 BU changed since last release and is now incorrect - Paper says: It was unexpected that the E401D as well as C205S and C211S mutations dramatically impaired the assembly of a catalysis-competent homodimer, suggesting novel links between the active site structure and dimer formation. -- Interesting: link between dimer formation and catalysis - automaticaly inferred from 1hxj 1e1f_2 PROBYES 1 2 NPS C2 11171077 11706179 BU changed since last release and is now incorrect - Paper says: It was unexpected that the E401D as well as C205S and C211S mutations dramatically impaired the assembly of a catalysis-competent homodimer, suggesting novel links between the active site structure and dimer formation. -- Interesting: link between dimer formation and catalysis - automaticaly inferred from 1hxj 1e1k NO 1 1 NPS NPS 10998235 10998235 SP says monomer - Paper says: FNRs (EC 1.18.1.2) are ubiquitous, monomeric enzymes harbouring one molecule of noncovalently bound FAD as prosthetic group [1, 2, 3 and 4]. They catalyse the reversible electron transfer between NADP(H) and the iron-sulfur protein ferredoxin (Fd) or FMN-containing flavodoxin (Fld). -- Annotation transfered from 1cjc 1e1l NO 1 1 NPS NPS 10998235 10998235 SP says monomer - Paper says: FNRs (EC 1.18.1.2) are ubiquitous, monomeric enzymes harbouring one molecule of noncovalently bound FAD as prosthetic group [1, 2, 3 and 4]. They catalyse the reversible electron transfer between NADP(H) and the iron-sulfur protein ferredoxin (Fd) or FMN-containing flavodoxin (Fld). -- Annotation transfered from 1cjc 1e1m NO 1 1 NPS NPS 10998235 10998235 SP says monomer - Paper says: FNRs (EC 1.18.1.2) are ubiquitous, monomeric enzymes harbouring one molecule of noncovalently bound FAD as prosthetic group [1, 2, 3 and 4]. They catalyse the reversible electron transfer between NADP(H) and the iron-sulfur protein ferredoxin (Fd) or FMN-containing flavodoxin (Fld). -- Annotation transfered from 1cjc 1e1n NO 1 1 NPS NPS 10998235 10998235 SP says monomer - Paper says: FNRs (EC 1.18.1.2) are ubiquitous, monomeric enzymes harbouring one molecule of noncovalently bound FAD as prosthetic group [1, 2, 3 and 4]. They catalyse the reversible electron transfer between NADP(H) and the iron-sulfur protein ferredoxin (Fd) or FMN-containing flavodoxin (Fld). -- Annotation transfered from 1cjc 1e1v NO 1 1 NPS NPS 10956187 10956187 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1e1x NO 1 1 NPS NPS 10956187 10956187 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1e1y NO 2 2 C2 C2 10924512 0 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1e1z NO 2 2 C2 C2 11124905 11124905 BU changed since last release and is now corrected - All similar structures are dimers or octamers, and this appears to be right. 1e20 NO 3 3 C3 C3 10986463 10986463 Paper says: Gel-filtration chromatography experiments show that AtHal3 is also a trimer in solution 1e21 NO 1 1 NPS NPS 11264578 11264578 1e26 PROBNOT 1 1 NPS NPS 11052789 0 PISA also says monomer - Human is monomeric so I guess it should be - Only Thermogota seems to be dimeric -- Annotation transfered from 1cd2 1e29 YES 1 2 NPS C2 11315568 11315568 Interface geometry conserved with 1f1c (48%) 1e2d NO 2 2 C2 C2 10873853 10873853 BU changed since last release and is now corrected - Seems well accepted that it is a dimer -- Annotation transfered from 1e2f 1e2e NO 2 2 C2 C2 10873853 10873853 BU changed since last release and is now corrected - Seems well accepted that it is a dimer -- Annotation transfered from 1e2f 1e2f NO 2 2 C2 C2 10873853 10873853 BU changed since last release and is now corrected - Seems well accepted that it is a dimer 1e2g NO 2 2 C2 C2 10873853 10873853 BU changed since last release and is now corrected - Seems well accepted that it is a dimer -- Annotation transfered from 1e2f 1e2o NO 24 24 Octa Octa 9677295 9677295 Interface geometry conserved with 1ead (32%) 1e2q NO 2 2 C2 C2 10873853 10873853 BU changed since last release and is now corrected - Seems well accepted that it is a dimer -- Annotation transfered from 1e2f 1e2r NO 2 2 C2 C2 10827177 10827177 Homodimer -- Annotation transfered from 1h9y 1e2s YES 1 2 NPS C2 0 0 All similar structures are dimers or octamers, and this appears to be right. -- Annotation transfered from 1e1z 1e2v_1 PROBNOT 1 1 NPS NPS 10924110 10869174 BU changed since last release and is now corrected - Paper says: distorted proper 2-fold rotation. This may represent the dimeric relation of the monomers in situ; however, the heme orientation suggested by this model is not consistent with previous EPR measurements on oriented membranes. - automaticaly inferred from 1cfm 1e2v_2 PROBNOT 1 1 NPS NPS 10924110 10869174 BU changed since last release and is now corrected - Paper says: distorted proper 2-fold rotation. This may represent the dimeric relation of the monomers in situ; however, the heme orientation suggested by this model is not consistent with previous EPR measurements on oriented membranes. - automaticaly inferred from 1cfm 1e2v_3 PROBNOT 1 1 NPS NPS 10924110 10869174 BU changed since last release and is now corrected - Paper says: distorted proper 2-fold rotation. This may represent the dimeric relation of the monomers in situ; however, the heme orientation suggested by this model is not consistent with previous EPR measurements on oriented membranes. - automaticaly inferred from 1cfm 1e2w_1 PROBNOT 1 1 NPS NPS 10924110 10869174 BU changed since last release and is now corrected - Paper says: distorted proper 2-fold rotation. This may represent the dimeric relation of the monomers in situ; however, the heme orientation suggested by this model is not consistent with previous EPR measurements on oriented membranes. - automaticaly inferred from 1cfm 1e2w_2 PROBNOT 1 1 NPS NPS 10924110 10869174 BU changed since last release and is now corrected - Paper says: distorted proper 2-fold rotation. This may represent the dimeric relation of the monomers in situ; however, the heme orientation suggested by this model is not consistent with previous EPR measurements on oriented membranes. - automaticaly inferred from 1cfm 1e2x NO 2 2 C2 C2 11013219 11013219 1e2y NO 10 10 D5 D5 10891277 10891277 Interface geometry conseved with 1qmv (57%) 1e2z_1 PROBNOT 1 1 NPS NPS 10924110 10869174 BU changed since last release and is now corrected - Paper says: distorted proper 2-fold rotation. This may represent the dimeric relation of the monomers in situ; however, the heme orientation suggested by this model is not consistent with previous EPR measurements on oriented membranes. - automaticaly inferred from 1cfm 1e2z_2 PROBNOT 1 1 NPS NPS 10924110 10869174 BU changed since last release and is now corrected - Paper says: distorted proper 2-fold rotation. This may represent the dimeric relation of the monomers in situ; however, the heme orientation suggested by this model is not consistent with previous EPR measurements on oriented membranes. - automaticaly inferred from 1cfm 1e2z_3 PROBNOT 1 1 NPS NPS 10924110 10869174 BU changed since last release and is now corrected - Paper says: distorted proper 2-fold rotation. This may represent the dimeric relation of the monomers in situ; however, the heme orientation suggested by this model is not consistent with previous EPR measurements on oriented membranes. - automaticaly inferred from 1cfm 1e30_1 PROBNOT 1 1 NPS NPS 11223511 8947572 SP says monomer - automatic transfer from 1rcy 1e30_2 PROBNOT 1 1 NPS NPS 11223511 8947572 SP says monomer - automatic transfer from 1rcy 1e31 NO 2 2 C2 C2 10949039 10949039 SP and paper say dimer 1e32 YES 1 6 NPS C6 11163219 11163219 SP says hexamer and paper too 1e33 NO 2 2 C2 C2 11777924 11124905 BU changed since last release and is now corrected - All similar structures are dimers or octamers, and this appears to be right. -- Annotation transfered from 1e1z 1e34 PROBNOT 1 1 NPS NPS 11023818 11023818 -- Annotation transfered from 1c1m 1e35 PROBNOT 1 1 NPS NPS 11023818 11023818 -- Annotation transfered from 1c1m 1e36 PROBNOT 1 1 NPS NPS 11023818 11023818 -- Annotation transfered from 1c1m 1e37 PROBNOT 1 1 NPS NPS 11023818 11023818 -- Annotation transfered from 1c1m 1e38 PROBNOT 1 1 NPS NPS 11023818 11023818 -- Annotation transfered from 1c1m 1e39 PROBNOT 1 1 NPS NPS 10978153 10978153 SP says monomer -- Annotation transfered from 1qjd 1e3b PROBYES 2 1 C2 NPS 11028014 0 BU changed since last release and is now incorrect - -- Annotation transfered from 1e8k 1e3c NO 2 2 C2 C2 11124905 11124905 BU changed since last release and is now corrected - All similar structures are dimers or octamers, and this appears to be right. -- Annotation transfered from 1e1z 1e3e NO 2 2 C2 C2 10970744 10970744 -- Annotation transfered from 1e3l 1e3f NO 4 4 D2 D2 10957627 10957627 transthyretin is tetrameric -- Annotation transfered from 1fh2 1e3g PROBNOT 1 1 NPS NPS 10840043 10840043 paper does not mention dimer and PISA says monomer 1e3i NO 2 2 C2 C2 10970744 10970744 -- Annotation transfered from 1e3l 1e3j NO 4 4 D2 D2 11237597 11237597 Interface geometry conserved with 1kev (26%) 1e3k_1 PROBYES 1 2 NPS C2 10840043 0 BU changed since last release and is now incorrect - no info in paper, PISA says dimer -- Annotation transfered from 1sr7 1e3k_2 PROBYES 1 2 NPS C2 10840043 0 BU changed since last release and is now incorrect - no info in paper, PISA says dimer -- Annotation transfered from 1sr7 1e3l NO 2 2 C2 C2 10970744 10970744 1e3o PROBNOT 1 1 NPS NPS 11583619 11583619 In the paper they show two subunits but they reconstructed it. They could not be observed in the crystal because the DNA seq is too short. 1e3q PROBNOT 1 1 NPS NPS 12351819 12351819 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1e3r NO 2 2 C2 C2 11007792 11007792 -- Annotation transfered from 1e3v 1e3s NO 4 4 D2 D2 11023795 11023795 paper says tetramer 1e3u_1 NO 2 2 C2 C2 11188693 11453693 Paper says dimer - interface geometry conserved with 1k38 (37%) - automatic transfer from 1h8z 1e3u_2 NO 2 2 C2 C2 11188693 11453693 Paper says dimer - interface geometry conserved with 1k38 (37%) - automatic transfer from 1h8z 1e3v NO 2 2 C2 C2 11007792 11007792 1e3w NO 4 4 D2 D2 11023795 11023795 Paper says tetramer 1e3x PROBNOT 1 1 NPS NPS 10924103 10924103 Paper says nothing, related proteins are monomers and PISA says monomer -- Annotation transfered from 1e3z 1e3z PROBNOT 1 1 NPS NPS 10924103 10924103 Paper says nothing, related proteins are monomers and PISA says monomer 1e40 PROBNOT 1 1 NPS NPS 10924103 10924103 Paper says nothing, related proteins are monomers and PISA says monomer -- Annotation transfered from 1e3z 1e43 PROBNOT 1 1 NPS NPS 10924103 10924103 Paper says nothing, related proteins are monomers and PISA says monomer -- Annotation transfered from 1e3z 1e46 NO 4 4 C4 C4 11054289 11054289 -- Annotation transfered from 1e4a 1e47 NO 4 4 C4 C4 11054289 11054289 -- Annotation transfered from 1e4a 1e48 NO 4 4 C4 C4 11054289 11054289 -- Annotation transfered from 1e4a 1e49 NO 4 4 C4 C4 11054289 11054289 -- Annotation transfered from 1e4a 1e4a NO 4 4 C4 C4 11054289 11054289 1e4b NO 4 4 C4 C4 11054289 11054289 -- Annotation transfered from 1e4a 1e4c NO 4 4 C4 C4 11054289 11054289 -- Annotation transfered from 1e4a 1e4e YES 4 2 C2 C2 10908650 10908650 BU changed since last release and is now incorrect - Interface geometry conseved with 1ehi (32%) 1e4h NO 4 4 D2 D2 10957627 10957627 transthyretin is tetrameric -- Annotation transfered from 1fh2 1e4i PROBNOT 8 8 D4 D4 0 0 BU changed since last release and is now corrected - See similar -- PISA does not find it! 1e4l_1 PROBYES 1 2 NPS C2 11106394 11706179 BU changed since last release and is now incorrect - Paper says: It was unexpected that the E401D as well as C205S and C211S mutations dramatically impaired the assembly of a catalysis-competent homodimer, suggesting novel links between the active site structure and dimer formation. -- Interesting: link between dimer formation and catalysis - automaticaly inferred from 1hxj 1e4l_2 PROBYES 1 2 NPS C2 11106394 11706179 BU changed since last release and is now incorrect - Paper says: It was unexpected that the E401D as well as C205S and C211S mutations dramatically impaired the assembly of a catalysis-competent homodimer, suggesting novel links between the active site structure and dimer formation. -- Interesting: link between dimer formation and catalysis - automaticaly inferred from 1hxj 1e4m NO 2 2 C2 C2 10978344 10978344 BU changed since last release and is now corrected - 1e4n PROBNOT 2 2 C2 C2 11106394 11106394 Paper says: It was unexpected that the E401D as well as C205S and C211S mutations dramatically impaired the assembly of a catalysis-competent homodimer, suggesting novel links between the active site structure and dimer formation. -- Interesting: link between dimer formation and catalysis -- Annotation transfered from 1hxj 1e4o NO 2 2 C2 C2 10469642 10469642 -- Annotation transfered from 2ecp 1e4v_1 PROBNOT 1 1 NPS NPS 8451239 0 BU changed since last release and is now corrected - SP and EcoCyc say monomer - automaticaly inferred from 1e4y 1e4v_2 PROBNOT 1 1 NPS NPS 8451239 0 BU changed since last release and is now corrected - SP and EcoCyc say monomer - automaticaly inferred from 1e4y 1e4y PROBYES 2 1 NS NPS 8451239 0 SP and EcoCyc say monomer 1e51 NO 8 8 D4 D4 0 0 BU changed since last release and is now corrected - No paper found but clear octamer 1e55_1 PROBYES 1 2 NPS C2 11106394 11706179 BU changed since last release and is now incorrect - Paper says: It was unexpected that the E401D as well as C205S and C211S mutations dramatically impaired the assembly of a catalysis-competent homodimer, suggesting novel links between the active site structure and dimer formation. -- Interesting: link between dimer formation and catalysis - automaticaly inferred from 1hxj 1e55_2 PROBYES 1 2 NPS C2 11106394 11706179 BU changed since last release and is now incorrect - Paper says: It was unexpected that the E401D as well as C205S and C211S mutations dramatically impaired the assembly of a catalysis-competent homodimer, suggesting novel links between the active site structure and dimer formation. -- Interesting: link between dimer formation and catalysis - automaticaly inferred from 1hxj 1e56_1 PROBNOT 2 2 C2 C2 11106394 11706179 Paper says: It was unexpected that the E401D as well as C205S and C211S mutations dramatically impaired the assembly of a catalysis-competent homodimer, suggesting novel links between the active site structure and dimer formation. -- Interesting: link between dimer formation and catalysis - automatic transfer from 1hxj 1e56_2 PROBYES 1 2 NPS C2 11106394 11706179 BU changed since last release and is now incorrect - Paper says: It was unexpected that the E401D as well as C205S and C211S mutations dramatically impaired the assembly of a catalysis-competent homodimer, suggesting novel links between the active site structure and dimer formation. -- Interesting: link between dimer formation and catalysis - automaticaly inferred from 1hxj 1e58 NO 2 2 C2 C2 11038361 11038361 BU changed since last release and is now corrected - Paper says dimer -- very very interesting protein for evolution: this one dimeric, same for Human, Yeast is tetrameric and S. Pombe is monomeric! 1e59 NO 2 2 C2 C2 11884145 11884145 BU changed since last release and is now corrected - Paper says dimer -- very very interesting protein for evolution: this one dimeric, same for Human, Yeast is tetrameric and S. Pombe is monomeric! -- Annotation transfered from 1e58 1e5a NO 4 4 D2 D2 10957627 10957627 transthyretin is tetrameric -- Annotation transfered from 1fh2 1e5d YES 4 2 D2 C2 11062560 11062560 Paper says dimer: ROO functions as a homodimer - 8503894: A rubredoxin-oxygen oxidoreductase, a homodimer with a molecular weight of 43 kDa per monomer 1e5e PROBNOT 4 4 D2 D2 0 0 BU changed since last release and is now corrected - No paper but close structures are tetramers and PISa says a tetramer exists. 1e5f PROBNOT 4 4 D2 D2 0 0 BU changed since last release and is now corrected - No paper but close structures are tetramers and PISa says a tetramer exists. -- Annotation transfered from 1e5e 1e5h PROBNOT 1 1 NPS NPS 11352583 0 this suggests that the trimeric structure of the apoenzyme found in the crystal might have some functional significance, for example in the protection of the C-terminal arm (rich in lysines and arginines) against proteases in the apo- or resting forms of DAOCS. However, DAOCS dissociates into monomers in the presence of Fe(II) and 2-oxoglutarate. -- Annotation transfered from 1hjf 1e5i PROBYES 3 1 C3 NPS 11352583 11352583 BU changed since last release and is now incorrect - this suggests that the trimeric structure of the apoenzyme found in the crystal might have some functional significance, for example in the protection of the C-terminal arm (rich in lysines and arginines) against proteases in the apo- or resting forms of DAOCS. However, DAOCS dissociates into monomers in the presence of Fe(II) and 2-oxoglutarate. -- Annotation transfered from 1hjf 1e5k PROBNOT 1 1 NPS NPS 11080634 11080634 Paper says : The MobA protein has been isolated previously, and it has proved to be monomeric in solution. - Other papers says equilibrium 1e5n PROBYES 2 2 C2 C2 11025547 11025547 They say in the paper that there is no evidence that it forms dimers in solution 1e5o PROBNOT 1 1 NPS NPS -1 0 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1e5p_1 NO 1 1 NPS NPS 11152604 11152604 BU changed since last release and is now corrected - Paper says: The surfaces buried in the interaction of each pair of molecules range from 0 to 276 Å2. These values represent less than 4 % of the total molecular surface (7080 (±105) Å2) and are far below the limit accepted for dimers present in solution, which indicates that aphrodisin should be a monomer in solution. Gel filtration experiments have confirmed this result. 1e5p_2 NO 1 1 NPS NPS 11152604 11152604 BU changed since last release and is now corrected - Paper says: The surfaces buried in the interaction of each pair of molecules range from 0 to 276 Å2. These values represent less than 4 % of the total molecular surface (7080 (±105) Å2) and are far below the limit accepted for dimers present in solution, which indicates that aphrodisin should be a monomer in solution. Gel filtration experiments have confirmed this result. 1e5p_3 NO 1 1 NPS NPS 11152604 11152604 BU changed since last release and is now corrected - Paper says: The surfaces buried in the interaction of each pair of molecules range from 0 to 276 Å2. These values represent less than 4 % of the total molecular surface (7080 (±105) Å2) and are far below the limit accepted for dimers present in solution, which indicates that aphrodisin should be a monomer in solution. Gel filtration experiments have confirmed this result. 1e5p_4 NO 1 1 NPS NPS 11152604 11152604 BU changed since last release and is now corrected - Paper says: The surfaces buried in the interaction of each pair of molecules range from 0 to 276 Å2. These values represent less than 4 % of the total molecular surface (7080 (±105) Å2) and are far below the limit accepted for dimers present in solution, which indicates that aphrodisin should be a monomer in solution. Gel filtration experiments have confirmed this result. 1e5w PROBNOT 1 1 NPS NPS 11401550 11401550 1e5y_1 PROBYES 2 1 C2 NPS 0 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 1e5y_2 PROBYES 2 1 C2 NPS 0 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 1e5z_1 PROBYES 2 1 C2 NPS 0 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 1e5z_2 PROBYES 2 1 C2 NPS 0 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 1e62 NO 1 1 NPS NPS 15789405 11152461 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1e63 NO 1 1 NPS NPS 15789405 11152461 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1e64 NO 1 1 NPS NPS 15789405 11152461 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1e65 PROBYES 4 1 D2 NPS 1633865 1633865 This is hard to believe but it seems that azurin is a monomeric protein! -- Annotation transfered from 5azu 1e66 PROBYES 2 1 C2 NPS 11863435 11863435 BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1e67 PROBYES 4 1 D2 NPS 1576995 1576995 This is hard to believe but it seems that azurin is a monomeric protein! -- Annotation transfered from 5azu 1e6a PROBNOT 2 2 C2 C2 11248042 11248042 SP says dimer -- Annotation transfered from 1wgi 1e6b NO 2 2 C2 C2 11352584 11352584 BU changed since last release and is now corrected - INterface geometry conserved with 1fw1 1e6c_1 PROBNOT 1 1 NPS NPS 11369852 11369852 BU changed since last release and is now corrected - Paper says: This monomeric enzyme shows 53% amino-acid identity to E. coli SK II and, at less than 19 kD, is one of the smallest kinases so far described. 1e6c_2 PROBNOT 1 1 NPS NPS 11369852 11369852 BU changed since last release and is now corrected - Paper says: This monomeric enzyme shows 53% amino-acid identity to E. coli SK II and, at less than 19 kD, is one of the smallest kinases so far described. 1e6e_2 PROBNOT 1 1 NPS NPS 11053423 9551550 BU changed since last release and is now corrected - Paper says nothing, PISA implies monomer - automaticaly inferred from 1ayf 1e6e_4 PROBNOT 1 1 NPS NPS 11053423 9551550 BU changed since last release and is now corrected - Paper says nothing, PISA implies monomer - automaticaly inferred from 1ayf 1e6g PROBNOT 1 1 NPS NPS 12006985 12006985 -- Annotation transfered from 1neg 1e6h PROBNOT 1 1 NPS NPS 12006985 12006985 -- Annotation transfered from 1neg 1e6k NO 1 1 NPS NPS 11023787 11023787 CheY is a Mr 14,000 monomeric protein -- Annotation transfered from 1chn 1e6l NO 1 1 NPS NPS 11023787 11023787 CheY is a Mr 14,000 monomeric protein -- Annotation transfered from 1chn 1e6m NO 1 1 NPS NPS 11023787 11023787 CheY is a Mr 14,000 monomeric protein -- Annotation transfered from 1chn 1e6q NO 2 2 C2 C2 10978344 10978344 -- Annotation transfered from 1e70 1e6s NO 2 2 C2 C2 10978344 10978344 -- Annotation transfered from 1e70 1e6u NO 2 2 C2 C2 11021971 0 SP and paper say dimer -- Annotation transfered from 1e7s 1e6w NO 4 4 D2 D2 11023795 11023795 paper says tetramer -- Annotation transfered from 1e3s 1e6x NO 2 2 C2 C2 10978344 10978344 -- Annotation transfered from 1e70 1e70 NO 2 2 C2 C2 10978344 0 1e71 NO 2 2 C2 C2 10978344 10978344 -- Annotation transfered from 1e70 1e72 NO 2 2 C2 C2 10978344 10978344 -- Annotation transfered from 1e70 1e73 NO 2 2 C2 C2 10978344 10978344 -- Annotation transfered from 1e70 1e77 NO 2 2 C2 C2 11106478 11106478 1e7m NO 2 2 C2 C2 11106478 11106478 -- Annotation transfered from 1e77 1e7n NO 2 2 C2 C2 11090271 11090271 True dimer but there is a SCOP error: should contain two domains and contains one only! -- Annotation transfered from 1bd7 1e7o PROBNOT 1 1 NPS NPS 12684010 0 -- Annotation transfered from 1neg 1e7q NO 2 2 C2 C2 11021971 11021971 SP and paper say dimer -- Annotation transfered from 1e7s 1e7r NO 2 2 C2 C2 11021971 11021971 SP and paper say dimer -- Annotation transfered from 1e7s 1e7s NO 2 2 C2 C2 11021971 11021971 SP and paper say dimer 1e7w NO 4 4 D2 D2 11373620 11373620 BU changed since last release and is now corrected - Paper says it is a tetramer 1e7y NO 2 2 C2 C2 11106478 11106478 -- Annotation transfered from 1e77 1e7z NO 1 1 NPS NPS 11157763 11157763 Monomer mimics the dimer -- very nice interesting example for a letter to the editor. 1e80 PROBNOT 1 1 NPS NPS -1 0 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1e81 PROBNOT 1 1 NPS NPS -1 0 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1e82 PROBNOT 1 1 NPS NPS -1 0 Most eukaryotic aspartic proteinases are monomeric 1e83 NO 2 2 C2 C2 11060017 11060017 Paper says dimer -- Annotation transfered from 1e84 1e84 NO 2 2 C2 C2 11060017 11060017 Paper says dimer 1e85 NO 2 2 C2 C2 11060017 11060017 BU changed since last release and is now corrected - Identicals are dimer and PISA says dimer 1e86 NO 2 2 C2 C2 11060017 11060017 Paper says dimer -- Annotation transfered from 1e84 1e87 NO 2 2 C2 C2 11036086 11036086 CD69 NKD dimerizes noncovalently, both in solution and in crystalline state. 1e89 NA 4 2 C2 C2 11316882 11316882 BU changed since last release and is now incorrect - Reported as a homotetramer in this paper but it seems that an equilibrium exists. Also multiple oligomeric states exists in homologous enzymes - interesting case. -- Annotation transfered from 1eb9 1e8a NO 2 2 C2 C2 11134923 11134923 Paper says dimer 1e8c_1 PROBNOT 1 1 NPS NPS 11124264 11124264 BU changed since last release and is now corrected - Paper implies monomer 1e8c_2 PROBNOT 1 1 NPS NPS 11124264 11124264 BU changed since last release and is now corrected - Paper implies monomer 1e8d NA 4 2 C2 C2 11316882 11316882 BU changed since last release and is now incorrect - Reported as a homotetramer in this paper but it seems that an equilibrium exists. Also multiple oligomeric states exists in homologous enzymes - interesting case. -- Annotation transfered from 1eb9 1e8f NO 8 8 D4 D4 10984479 0 Paper says octamer -- Annotation transfered from 2vao 1e8g YES 2 8 C2 D4 10984479 0 BU changed since last release and is now incorrect - Paper says octamer -- Annotation transfered from 2vao 1e8h PROBYES 2 8 C2 D4 10984479 0 Paper says: Analytical gel filtration experiments showed that the His422 mutants are mainly in the octameric form with a small portion being present as a dimer. - dimer octamer equilibrium -- Annotation transfered from 1qlt 1e8i NO 2 2 C2 C2 11036086 11036086 CD69 NKD dimerizes noncovalently, both in solution and in crystalline state. -- Annotation transfered from 1e87 1e8k PROBNOT 1 1 NPS NPS 11180378 11180378 1e92 NO 4 4 D2 D2 11373620 0 1e93 NO 4 4 D2 D2 8901874 8901874 BU changed since last release and is now corrected - Interface geometry conserved with 1m7s (40% id) 1e94_3 NO 6 6 C6 C6 0 10693812 HSLU is the outer ring so it forms a hexamer (not a dodecamer) - automatic transfer from 1do0 1e97 NO 2 2 C2 C2 11389596 11389596 BU changed since last release and is now corrected - All identical are dimers and PISA says dimer for this one 1e98 NO 2 2 C2 C2 11071809 11071809 BU changed since last release and is now corrected - Seems well accepted that it is a dimer -- Annotation transfered from 1e2f 1e99 NO 2 2 C2 C2 11071809 11071809 BU changed since last release and is now corrected - Seems well accepted that it is a dimer -- Annotation transfered from 1e2f 1e9a NO 2 2 C2 C2 11071809 11071809 BU changed since last release and is now corrected - Seems well accepted that it is a dimer -- Annotation transfered from 1e2f 1e9b NO 2 2 C2 C2 11071809 11071809 BU changed since last release and is now corrected - Seems well accepted that it is a dimer -- Annotation transfered from 1e2f 1e9c NO 2 2 C2 C2 11071809 11071809 BU changed since last release and is now corrected - Seems well accepted that it is a dimer -- Annotation transfered from 1e2f 1e9d NO 2 2 C2 C2 11071809 11071809 BU changed since last release and is now corrected - Seems well accepted that it is a dimer -- Annotation transfered from 1e2f 1e9e NO 2 2 C2 C2 11071809 11071809 BU changed since last release and is now corrected - Seems well accepted that it is a dimer -- Annotation transfered from 1e2f 1e9f NO 2 2 C2 C2 11071809 11071809 BU changed since last release and is now corrected - Seems well accepted that it is a dimer -- Annotation transfered from 1e2f 1e9g PROBNOT 2 2 C2 C2 11248042 8994974 SP says dimer - automatic transfer from 1wgi 1e9i_1 NO 2 2 C2 C2 11676541 11676541 Interface conserved with 1one (50% id) 1e9i_2 NO 2 2 C2 C2 11676541 11676541 Interface conserved with 1one (50% id) -- Annotation transfered from 1e9i_1 1e9l PROBNOT 1 1 NPS NPS 11278670 11278670 Ym1 has been purified and characterized as a single chain polypeptide with an estimated molecular mass of 45 kDa 1e9m PROBNOT 1 1 NPS NPS 11173487 11173487 Paper mentions gel filtration and ultracentrif and no oligomer - PISA says monomer 1e9r NO 6 6 C6 C6 11214325 11214325 BU changed since last release and is now corrected - Paper says: Six equivalent protein monomers associate to form an almost spherical quaternary structure that is strikingly similar to F1-ATPase - automatic transfer from 1e9s_2 1e9s_1 NO 6 6 C6 C6 11214325 11214325 BU changed since last release and is now corrected - Paper says: Six equivalent protein monomers associate to form an almost spherical quaternary structure that is strikingly similar to F1-ATPase 1e9s_2 NO 6 6 C6 C6 11214325 11214325 BU changed since last release and is now corrected - Paper says: Six equivalent protein monomers associate to form an almost spherical quaternary structure that is strikingly similar to F1-ATPase 1e9x PROBNOT 1 1 NPS NPS 11248033 11248033 11304120 says P450s are monomeric enzymes -- Annotation transfered from 1u13 1ea1 PROBNOT 1 1 NPS NPS 11248033 11248033 11304120 says P450s are monomeric enzymes -- Annotation transfered from 1u13 1ea2 NO 2 2 C2 C2 11389596 11389596 BU changed since last release and is now corrected - All identical are dimers and PISA says dimer for this one -- Annotation transfered from 1e97 1ea5 PROBNOT 1 1 NPS NPS 0 0 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1eaa NO 24 24 Octa Octa 8471601 1549782 Interface geometry conserved with 1e2o (32%) -- Annotation transfered from 1ead 1eab NO 24 24 Octa Octa 8471601 1549782 Interface geometry conserved with 1e2o (32%) -- Annotation transfered from 1ead 1eac NO 24 24 Octa Octa 8471601 1549782 Interface geometry conserved with 1e2o (32%) -- Annotation transfered from 1ead 1ead NO 24 24 Octa Octa 8471601 7703242 Interface geometry conserved with 1e2o (32%) 1eae NO 24 24 Octa Octa 8471601 1549782 Interface geometry conserved with 1e2o (32%) -- Annotation transfered from 1ead 1eaf NO 24 24 Octa Octa 8471601 1549782 Interface geometry conserved with 1e2o (32%) -- Annotation transfered from 1ead 1eag PROBYES 2 1 C2 NPS 8591036 8591036 Paper implies it is monomeric: Assignments were in agreement typical of the monomeric aspartic-proteinase family. -- good example of large crystal contact 1eaj NO 2 2 C2 C2 11080637 11080637 Paper says dimer -- Annotation transfered from 1f5w 1eak_1 YES 2 1 C2 NPS 0 0 BU changed since last release and is now incorrect - No paper found but this is a fragment (400 aa out of 600) of a larger assembly: 1ck7. The contact takes place where the domain has been cut so definitly not relevant. -- good interesting example to show that manual curation can be well done without biological experiments!! 1eak_2 YES 2 1 C2 NPS 0 0 BU changed since last release and is now incorrect - No paper found but this is a fragment (400 aa out of 600) of a larger assembly: 1ck7. The contact takes place where the domain has been cut so definitly not relevant. -- good interesting example to show that manual curation can be well done without biological experiments!! 1eam PROBNOT 1 1 NPS NPS 10377383 10377383 SP and PISA say monomer 1eas PROBNOT 1 1 NPS NPS 7932559 7932559 -- Annotation transfered from 1c1m 1eat PROBNOT 1 1 NPS NPS 7837246 7837246 -- Annotation transfered from 1c1m 1eau PROBNOT 1 1 NPS NPS 7837235 7837235 -- Annotation transfered from 1c1m 1eav_1 NO 3 3 C3 C3 11554796 11554796 BU changed since last release and is now corrected - Interface geometry conserved with 1jlj (52%) -- Annotation transfered from 1o8q 1eav_2 NO 3 3 C3 C3 11554796 11554796 BU changed since last release and is now corrected - Interface geometry conserved with 1jlj (52%) -- Annotation transfered from 1o8q 1eav_3 NO 3 3 C3 C3 11554796 11554796 BU changed since last release and is now corrected - Interface geometry conserved with 1jlj (52%) -- Annotation transfered from 1o8q 1eav_4 NO 3 3 C3 C3 11554796 11554796 BU changed since last release and is now corrected - Interface geometry conserved with 1jlj (52%) -- Annotation transfered from 1o8q 1eax PROBNOT 1 1 NPS NPS 11696548 11696548 Paper says nothing - related are monomers and PISA says monomer 1eb2 PROBNOT 1 1 NPS NPS 11881991 0 -- Annotation transfered from 1az8 1eb3 NO 8 8 D4 D4 11513881 11513881 BU changed since last release and is now corrected - Paper says octamer -- Annotation transfered from 1h7o 1eb4 NO 4 4 D2 D2 11796111 11796111 BU changed since last release and is now corrected - Clear homo-tetramer (ch. 1b8f) -- Annotation transfered from 1gkm 1eb8 NA 4 2 C2 C2 11742123 11742123 BU changed since last release and is now incorrect - Reported as a homotetramer in this paper but it seems that an equilibrium exists. Also multiple oligomeric states exists in homologous enzymes - interesting case. -- Annotation transfered from 1eb9 1eb9 NA 4 2 C2 C2 11742123 9030531 BU changed since last release and is now incorrect - Reported as a homotetramer in this paper but it seems that an equilibrium exists. Also multiple oligomeric states exists in homologous enzymes - interesting case. 1ebb NO 1 1 NPS NPS 11827481 11827481 Paper says monomer 1ebc NO 1 1 NPS NPS 10423453 10423453 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1ebe PROBNOT 1 1 NPS NPS 8069633 8069633 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1ebg NO 2 2 C2 C2 8049235 8605183 Interface conserved with 1te6 (62% id) -- Annotation transfered from 1one 1ebh NO 2 2 C2 C2 7703246 8605183 Interface conserved with 1te6 (62% id) -- Annotation transfered from 1one 1ebl NO 2 2 C2 C2 10673437 10673437 -- Annotation transfered from 1hnj 1ebv PROBYES 1 2 NPS C2 11723249 11723249 PISA says monomer but this is quite strange. - look further 1ebw NO 2 2 C2 C2 12694187 12694187 -- Annotation transfered from 1ajx 1eby NO 2 2 C2 C2 12694187 12694187 -- Annotation transfered from 1ajx 1ebz NO 2 2 C2 C2 12694187 12694187 -- Annotation transfered from 1ajx 1ec0 NO 2 2 C2 C2 15560801 15560801 -- Annotation transfered from 1ajx 1ec1 NO 2 2 C2 C2 12694187 12694187 -- Annotation transfered from 1ajx 1ec2 NO 2 2 C2 C2 12694187 12694187 -- Annotation transfered from 1ajx 1ec3 NO 2 2 C2 C2 12694187 12694187 -- Annotation transfered from 1ajx 1ec5_1 PROBNOT 2 2 C2 C2 10841536 0 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Four helix bundle -- Check symmetry search - automaticaly inferred from 1ovu 1ec5_2 PROBNOT 2 2 C2 C2 10841536 0 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Four helix bundle -- Check symmetry search - automaticaly inferred from 1ovu 1ec7 NO 4 4 D2 D2 10769114 10769114 Paper says tetramer, EcoCyc is wrong -- Annotation transfered from 1ec8 1ec8 NO 4 4 D2 D2 10769114 10769114 Paper says tetramer, EcoCyc is wrong 1ec9 NO 4 4 D2 D2 10769114 10769114 Paper says tetramer, EcoCyc is wrong -- Annotation transfered from 1ec8 1ecl PROBNOT 1 1 NPS NPS 8114910 8114910 SP says monomer -- Annotation transfered from 1mw8 1ecp NO 6 6 D3 D3 9351810 9351810 Paper and SP say hexamer -- Annotation transfered from 1ovg 1ecq NO 4 4 D2 D2 10769114 10769114 Paper says tetramer, EcoCyc is wrong -- Annotation transfered from 1ec8 1ecv PROBNOT 1 1 NPS NPS 10702277 10702277 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1ecx YES 2 2 NS C2 10715213 10715213 1ecy NO 2 2 C2 C2 8931142 8931142 Native form of Ecotin, which is dimeric 1ecz NO 2 2 C2 C2 8931142 8931142 Native form of Ecotin, which is dimeric -- Annotation transfered from 1ecy 1ed4 NO 2 2 C2 C2 11051558 11051558 Clear dimer -- Annotation transfered from 1fol 1ed5 NO 2 2 C2 C2 11695891 11695891 Clear dimer -- Annotation transfered from 1fol 1ed6 NO 2 2 C2 C2 11331003 11331003 Clear dimer -- Annotation transfered from 1fol 1edb NO 1 1 NPS NPS 8369276 8369276 SP says monomer 1edd NO 1 1 NPS NPS 8369276 8369276 SP says monomer -- Annotation transfered from 1edb 1ede NO 1 1 NPS NPS 8355275 8355275 SP says monomer -- Annotation transfered from 1edb 1edh NO 2 2 C2 C2 8598933 8598933 Cadherin homodimer 1edm PROBNOT 2 2 NS NS 7606779 7606779 Paper suggests it is relevant 1edo NO 4 4 D2 D2 10801480 10801480 paper says tetramer 1edq PROBNOT 1 1 NPS NPS 12554965 12554965 -- Annotation transfered from 1ehn 1edt PROBYES 2 1 C2 NPS 7663942 7663942 Looks like it is crystal contacts - PISA also says monomer 1edy PROBYES 4 1 NS NPS 11106161 11106161 9634697 says: The αMs exist as monomers, or as dimeric and tetrameric assemblies of approximately 180 kDa subunits 1ee0 NO 2 2 C2 C2 11137815 11137815 -- Annotation transfered from 1qlv 1ee2 NO 2 2 C2 C2 11041853 11041853 -- Annotation transfered from 8adh 1ee4_1 NO 1 1 NPS NPS 10745017 10745017 Paper says: To prevent the dimerization of Kapα50 we engineered a point mutation (Tyr→Asp at position 397, Y397D). -- Interesting case of dimer interference by one point mutation. -- Annotation transfered from 1ee5 1ee4_2 NO 1 1 NPS NPS 10745017 10745017 Paper says: To prevent the dimerization of Kapα50 we engineered a point mutation (Tyr→Asp at position 397, Y397D). -- Interesting case of dimer interference by one point mutation. -- Annotation transfered from 1ee5 1ee5 NO 1 1 NPS NPS 10745017 10745017 Paper says: To prevent the dimerization of Kapα50 we engineered a point mutation (Tyr→Asp at position 397, Y397D). -- Interesting case of dimer interference by one point mutation. 1ee8 PROBYES 2 1 C2 NPS 10921868 10921868 Paper says nothing, PISA says monomer and these proteins are monomeric 1eea PROBYES 4 4 D2 NA -1 0 BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. 1eed PROBNOT 1 1 NPS NPS 1525155 1525155 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1eem NO 2 2 C2 C2 10783391 10783391 1een PROBNOT 1 1 NPS NPS 10889023 10889023 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1eeo PROBNOT 1 1 NPS NPS 10889023 10889023 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1eeq NO 2 2 C2 C2 11751325 11751325 Interface conserved down to <30% (1cd8)! -- Annotation transfered from 1lve 1eeu NO 2 2 C2 C2 12070321 12070321 Interface conserved down to <30% (1cd8)! -- Annotation transfered from 1lve 1ef0 PROBYES 2 1 C2 NPS 10828056 10601013 From the paper it seems to be a monomer. 1ef2 NO 9 9 C3 C3 10555581 10555581 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1ef3 NA 2 1 C2 NPS 10882376 10882376 Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. 1ef8 YES 3 6 C3 D3 10769118 10769118 paper says hexamer 1ef9 YES 1 6 NPS D3 10769118 10769118 paper says hexamer 1efc_1 PROBNOT 1 1 NPS NPS 9918724 9838020 BU changed since last release and is now corrected - EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa. - automaticaly inferred from 1dg1 1efc_2 PROBNOT 1 1 NPS NPS 9918724 9838020 BU changed since last release and is now corrected - EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa. - automaticaly inferred from 1dg1 1efh_1 PROBYES 2 2 NS C2 10854859 14573603 BU changed since last release and is now incorrect - the active protein is a homodimer in solution and this interface is conserved among other distant proteins so it is surely right. - automaticaly inferred from 1ov4 1efh_2 PROBYES 2 2 NS C2 10854859 14573603 BU changed since last release and is now incorrect - the active protein is a homodimer in solution and this interface is conserved among other distant proteins so it is surely right. - automaticaly inferred from 1ov4 1efq NA 1 1 NPS NPS 12070321 12070321 Normally dimeric but mutations have been introduced that induce a particular crystal packing where the dimer is not seen 1eft NO 1 1 NPS NPS 8069622 8069622 EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa -- Annotation transfered from 1exm 1efw_1 PROBYES 1 2 NPS C2 10843857 7966328 BU changed since last release and is now incorrect - Interface geometry conserved with 1c0a (48%) - automaticaly inferred from 1g51 1efw_2 PROBYES 1 2 NPS C2 10843857 7966328 BU changed since last release and is now incorrect - Interface geometry conserved with 1c0a (48%) - automaticaly inferred from 1g51 1eg1 YES 4 1 C2 NPS 9325098 9325098 Paper says nothing - email sent - reply: When I was working with that enzyme I never saw any dimer in gel filtration or native gel electrophoresis, neither of the intact full-length enzyme or the catalytic domain alone. It has a tendency to precipitate above pH 6. Perhaps this behavior starts with dimerisation. I dont know. I would say that the natural physiological state of the enzyme in solution is monomeric. 1eg2 NO 1 1 NPS NPS 11024175 11024175 Paper says: The most studied of these classes, type II restriction modification systems, usually have a dimeric endonuclease and a monomeric MTase that requires only the methyl-donating cofactor S-adenosyl-L-methionine (AdoMet) for activity. Here the MTase is of type II -- Annotation transfered from 1nw5 1eg5 NO 2 2 C2 C2 10715213 10715213 1eg9 NO 6 6 C3 C3 10669618 10669618 Interface geometry conserved with 1ulj (28%) -- Annotation transfered from 1ndo 1egg YES 2 2 C2 C2 10779515 10779515 Domain Swapped dimer -- wrong reconstruction -- good example of very dumb PDB stuff 1egi YES 2 2 C2 C2 10779515 10779515 Domain Swapped dimer -- wrong reconstruction -- good example of very dumb PDB stuff -- Annotation transfered from 1egg 1egn PROBNOT 1 1 NPS NPS 11336632 11336632 None of the papers speaks about a dimer - a dimer is found using PISA but visual inspection reveals a weak interface. -- Annotation transfered from 6cel 1egq PROBNOT 1 1 NPS NPS 11438752 11438752 -- Annotation transfered from 1p7v 1egy PROBNOT 1 1 NPS NPS 10716705 10716705 Paper does not mention oligomer - PISA says monomer - many instances of monomers 1eh4_1 PROBNOT 1 1 NPS NPS 10749871 7759525 BU changed since last release and is now corrected - Origonal paper says nothing - CK1 usually accepted as monomeric (cf paper). - automaticaly inferred from 2csn 1eh4_2 PROBNOT 1 1 NPS NPS 10749871 7759525 BU changed since last release and is now corrected - Origonal paper says nothing - CK1 usually accepted as monomeric (cf paper). - automaticaly inferred from 2csn 1ehb PROBNOT 1 1 NPS NPS 10842340 10842340 Oligomeric state not mentioned - PISA says monomer -- Annotation transfered from 1lqx 1ehc NO 1 1 NPS NPS 9115243 9115243 CheY is a Mr 14,000 monomeric protein -- Annotation transfered from 1chn 1ehe PROBNOT 1 1 NPS NPS 11051564 11051564 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer -- Annotation transfered from 1cmj 1ehf PROBNOT 1 1 NPS NPS 11051564 11051564 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer -- Annotation transfered from 1cmj 1ehg PROBNOT 1 1 NPS NPS 11051564 11051564 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer -- Annotation transfered from 1cmj 1ehi NO 2 2 C2 C2 10801495 10801495 Interface geometry conseved with 1iow (34%) 1ehn PROBNOT 1 1 NPS NPS 11560481 11560481 1ehw NO 6 6 D3 D3 10799505 10799505 SP says hexamer 1eib PROBNOT 1 1 NPS NPS 11560481 11560481 -- Annotation transfered from 1ehn 1eic NO 1 1 NPS NPS 11742124 11742124 -- Annotation transfered from 6rsa 1eid NO 1 1 NPS NPS 11742124 11742124 -- Annotation transfered from 6rsa 1eie NO 1 1 NPS NPS 11742124 11742124 -- Annotation transfered from 6rsa 1eil NO 8 8 D4 D4 11293547 11293547 Interface geometry conserved with 1lgt (66%) 1ein_1 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1ein_2 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1ein_3 PROBNOT 1 1 NPS NPS 11106485 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1eiq NO 8 8 D4 D4 11293547 11293547 Interface geometry conserved with 1lgt (66%) -- Annotation transfered from 1eil 1eir NO 8 8 D4 D4 11293547 11293547 Interface geometry conserved with 1lgt (66%) -- Annotation transfered from 1eil 1eix_1 NO 2 2 C2 C2 10757968 12054799 SP says dimer - interface geometry conserved with 1lor (23%) - automatic transfer from 1l2u 1eix_2 NO 2 2 C2 C2 10757968 12054799 SP says dimer - interface geometry conserved with 1lor (23%) - automatic transfer from 1l2u 1eiz PROBNOT 1 1 NPS NPS 10983982 10983982 EcoCyc says monomer 1ej0 PROBNOT 1 1 NPS NPS 10983982 10983982 EcoCyc says monomer -- Annotation transfered from 1eiz 1ej2 PROBYES 1 6 NPS D3 11063748 11063748 NMNATase proteins have been identified, purified, and characterized from archaea, bacteria, and eukarya. All of these proteins are oligomeric; trimeric, tetrameric, and hexameric forms have been observed. Ref is: Enzymology of NAD+ synthesis (not available to download) - interesting 1ejb NO 5 5 C5 C5 10860731 10860731 Paper says pentamer 1ejc PROBNOT 1 1 NPS NPS 10842342 10842342 MurA crystallizes from PEG 20000 as a monomeric species. -- Annotation transfered from 1eyn 1ejd_1 PROBNOT 1 1 NPS NPS 10842342 10823915 MurA crystallizes from PEG 20000 as a monomeric species. - automatic transfer from 1eyn 1ejd_2 PROBNOT 1 1 NPS NPS 10842342 10823915 MurA crystallizes from PEG 20000 as a monomeric species. - automatic transfer from 1eyn 1ejg PROBNOT 1 1 NPS NPS 10737790 10737790 Although no clear reference was found, it is accepted to me that crambin is at least predominantly monomeric in somution. -- this family is a MESSSS -- Annotation transfered from 1cbn 1eji NO 4 4 D2 D2 11063567 11063567 Paper says tetramer 1ejl PROBNOT 1 1 NPS NPS 10764582 10764582 Paper says: suggesting that both proteins are monomeric under these conditions -- Annotation transfered from 1iq1 1ejn PROBNOT 1 1 NPS NPS 10805774 10805774 -- Annotation transfered from 1owd 1ejr NO 9 9 C3 C3 10913264 10913264 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1ejs NO 9 9 C3 C3 10913264 10913264 Interface geometry conserved with 4ubp (64% id avg) 1ejt NO 9 9 C3 C3 10913264 10913264 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1eju NO 9 9 C3 C3 10913264 10913264 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1ejv NO 9 9 C3 C3 10913264 10913264 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1ejw NO 9 9 C3 C3 0 0 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1ejx NO 9 9 C3 C3 0 0 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1ejy PROBNOT 1 1 NPS NPS 10764582 10764582 Paper says: suggesting that both proteins are monomeric under these conditions -- Annotation transfered from 1iq1 1ek0 PROBNOT 1 1 NPS NPS 10756108 10756108 Paper says nothing, PISA says monomer 1ek3 PROBNOT 2 2 C2 C2 0 0 Similar ones (4lve) pack similarly and are true. 1ek5 NO 2 2 C2 C2 10801319 10801319 Paper says dimer -- Annotation transfered from 1i3l 1ek6 NO 2 2 C2 C2 10801319 10801319 Paper says dimer -- Annotation transfered from 1i3l 1ekb PROBNOT 1 1 NPS NPS 10493881 10493881 Paper says heretodimer with a 1:1 stoichiometry. 1eke PROBYES 2 1 C2 NPS 10997908 10997908 Paper says nothing, PISA says monomer 1ekf NO 2 2 C2 C2 11264579 11264579 Paper says dimer: The mammalian BCATs are homodimers with molecular masses ranging from about 41000 to 46000. - SP too -- Annotation transfered from 1kta 1ekj_1 8 12 D2 D2 10747009 10747009 BU changed since last release and is now incorrect - I think the interfaces found here are homologous to those seen in 2a5v, 1ym3 and 1ylk... 1ekj_2 8 12 D2 D2 10747009 10747009 BU changed since last release and is now incorrect - I think the interfaces found here are homologous to those seen in 2a5v, 1ym3 and 1ylk... - automatic transfer from 1ekj_1 1ekk_1 NO 3 3 C3 C3 10891066 10891066 Interface geometry conserved with 1v8a (43%) - automatic transfer from 1esq 1ekk_2 NO 3 3 C3 C3 10891066 10891066 Interface geometry conserved with 1v8a (43%) - automatic transfer from 1esq 1ekm_1 PROBNOT 2 2 C2 C2 10933787 15299901 BU changed since last release and is now corrected - Paper says dimer - automaticaly inferred from 1a2v 1ekm_2 PROBNOT 2 2 C2 C2 10933787 15299901 BU changed since last release and is now corrected - Paper says dimer - automaticaly inferred from 1a2v 1eko NO 1 1 NPS NPS 10771421 10771421 SwissProt an dPISA say monomer -- Annotation transfered from 1ah3 1ekp NO 2 2 C2 C2 11264579 11264579 Paper says dimer: The mammalian BCATs are homodimers with molecular masses ranging from about 41000 to 46000. - SP too -- Annotation transfered from 1kta 1ekq_1 NO 3 3 C3 C3 10891066 10891066 Interface geometry conserved with 1v8a (43%) - automatic transfer from 1esq 1ekq_2 NO 3 3 C3 C3 10891066 10891066 Interface geometry conserved with 1v8a (43%) - automatic transfer from 1esq 1ekv NO 2 2 C2 C2 11264579 11264579 Paper says dimer: The mammalian BCATs are homodimers with molecular masses ranging from about 41000 to 46000. - SP too -- Annotation transfered from 1kta 1ekx NO 3 3 C3 C3 10805770 10805770 -- Annotation transfered from 1gq3 1el1_1 NO 1 1 NPS NPS 0 10727216 - automatic transfer from 1qqy 1el1_2 NO 1 1 NPS NPS 0 10727216 - automatic transfer from 1qqy 1el3 NO 1 1 NPS NPS 10771421 10771421 SwissProt and PISA say monomer -- Annotation transfered from 1ads 1el4 PROBNOT 1 1 NPS NPS 11152120 11152120 Paper does not mention a dimer - PISA says monomer -- Annotation transfered from 1jf2 1ela PROBNOT 1 1 NPS NPS 7656008 7656008 -- Annotation transfered from 1c1m 1elb PROBNOT 1 1 NPS NPS 7656008 7656008 -- Annotation transfered from 1c1m 1elc PROBNOT 1 1 NPS NPS 7656008 7656008 -- Annotation transfered from 1c1m 1eld PROBNOT 1 1 NPS NPS 7880814 7880814 -- Annotation transfered from 1c1m 1ele PROBNOT 1 1 NPS NPS 7880814 7880814 -- Annotation transfered from 1c1m 1elf PROBNOT 1 1 NPS NPS 7779821 7779821 -- Annotation transfered from 1c1m 1elg PROBNOT 1 1 NPS NPS 7779821 7779821 -- Annotation transfered from 1c1m 1elp PROBYES 2 1 NS NPS 15299634 3052280 y-Crystallins are exclusively monomeric 1elq NO 2 2 C2 C2 10760256 10760256 -- Annotation transfered from 1n31 1els NO 2 2 C2 C2 8193144 8605183 Interface conserved with 1te6 (62% id) -- Annotation transfered from 1one 1elt PROBNOT 1 1 NPS NPS 15299762 0 PISA says monomer, porcine elastase is monomeric 1elu NO 2 2 C2 C2 10760256 10760256 -- Annotation transfered from 1n31 1em1 NO 4 4 D2 D2 10852710 10852710 Paper says tetramer -- Annotation transfered from 1n0j 1em6 NO 2 2 C2 C2 10980448 10980448 -- Annotation transfered from 1fc0 1em7 PROBNOT 1 1 NPS NPS 10933505 10933505 12379842 implies it is monomeric, PISA also says monomeric 1ema NO 1 1 NPS NPS 8703075 8703075 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1emb NO 1 1 NPS NPS 9122190 9122190 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1emc YES 4 1 NS NPS 9145105 9145105 1emd NO 2 2 C2 C2 8331658 8331658 Paper says dimer -- Annotation transfered from 2cmd 1eme PROBNOT 2 2 C2 C2 9145105 9145105 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 2emo 1emf PROBNOT 2 2 C2 C2 9145105 9145105 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 2emo 1emg NO 1 1 NPS NPS 10220315 10220315 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1emk PROBNOT 2 2 C2 C2 9145105 9145105 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 2emo 1eml PROBNOT 2 2 C2 C2 9145105 9145105 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 2emo 1emm PROBNOT 2 2 C2 C2 9145105 9145105 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 2emo 1emu ART 1 1 NPS NPS 10811618 10811618 BU changed since last release and is now corrected - Paper says: Recently, Axin has also been shown to homodimerize - PISA also finds a dimer. However, the protein length here is 150 aa while the full length is 2800 aa. So I doubt that it s relevant and I ll consider it as a monomer and artifact. - automaticaly inferred from 1dk8 1emy NO 1 1 NPS NPS 7657658 7657658 Myoglobin is well known to be monomeric 1en4_1 NO 2 2 C2 C2 11141052 11294629 PAper, SP say dimer - automatic transfer from 1i0h 1en4_2 NO 2 2 C2 C2 11141052 11294629 PAper, SP say dimer - automatic transfer from 1i0h 1en5_1 NO 2 2 C2 C2 11141052 11294629 PAper, SP say dimer - automatic transfer from 1i0h 1en5_2 NO 2 2 C2 C2 11141052 11294629 PAper, SP say dimer - automatic transfer from 1i0h 1en6_1 NO 2 2 C2 C2 11141052 11294629 PAper, SP say dimer - automatic transfer from 1i0h 1en6_2 NO 2 2 C2 C2 11141052 11294629 PAper, SP say dimer - automatic transfer from 1i0h 1ena NO 1 1 NPS NPS 8025105 7552745 Paper says monomeric 1enc NO 1 1 NPS NPS 8025105 8025105 Paper says monomeric -- Annotation transfered from 1ena 1eno NO 4 4 D2 D2 8535786 8535786 paper and SP say tetramer 1enp NO 4 4 D2 D2 8535786 8535786 paper and SP say tetramer -- Annotation transfered from 1eno 1enq NO 4 4 D2 D2 8663112 8663112 SP says tetramer -- Annotation transfered from 1cjp 1enr NO 4 4 D2 D2 8663112 8663112 SP says tetramer -- Annotation transfered from 1cjp 1ens NO 4 4 D2 D2 8663112 8663112 SP says tetramer -- Annotation transfered from 1cjp 1ent PROBNOT 1 1 NPS NPS 2179568 2179568 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1eny YES 2 4 C2 D2 7886450 7886450 1enz YES 2 4 C2 D2 7886450 7886450 -- Annotation transfered from 1eny 1eo5 NO 1 1 NPS NPS 10869182 10869182 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1eo6 YES 2 1 NS NPS 10856287 10856287 Paper says: It should be noted that GATE-16 behaves as a monomer under physiological conditions in solution as determined by gel filtration and analytical ultracentrifugation (data not shown). 1eo7 NO 1 1 NPS NPS 10869182 10869182 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1eod YES 1 4 NPS C4 10802739 10802739 Interface geometry conserved with 3kvt (42%) -- PISA doesnt find it -- Annotation transfered from 1eof 1eoe YES 1 4 NPS C4 10802739 10802739 Interface geometry conserved with 3kvt (42%) -- PISA doesnt find it -- Annotation transfered from 1eof 1eof YES 1 4 NPS C4 10802739 10802739 Interface geometry conserved with 3kvt (42%) -- PISA doesnt find it 1eog NO 2 2 C2 C2 10970734 10970734 -- Annotation transfered from 9gss 1eoh_1 NO 2 2 C2 C2 10970734 9398518 - automatic transfer from 9gss 1eoh_2 NO 2 2 C2 C2 10970734 9398518 - automatic transfer from 9gss 1eoh_3 NO 2 2 C2 C2 10970734 9398518 - automatic transfer from 9gss 1eoh_4 NO 2 2 C2 C2 10970734 9398518 - automatic transfer from 9gss 1eoi NO 6 6 D3 D3 10835340 10835340 Paper says: The enzyme is a 150 kDa homohexamer. 1eoj PROBNOT 1 1 NPS NPS 10694407 10694407 -- Annotation transfered from 1doj 1eol PROBNOT 1 1 NPS NPS 10694407 10694407 -- Annotation transfered from 1doj 1eos_1 PROBNOT 1 1 NPS NPS 10892814 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1eos_2 PROBNOT 1 1 NPS NPS 10892814 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1eou PROBNOT 1 1 NPS NPS 11802772 11802772 9000633 says monomeric -- Annotation transfered from 1uga 1eow NO 1 1 NPS NPS 10892814 10892814 -- Annotation transfered from 6rsa 1ep0 NO 2 2 C2 C2 10827167 10827167 Interface geometry conserved with 1rtv (49%) 1ep5 PROBYES 3 1 NS NPS 0 0 No paper found, PISA says monomer 1ep6 PROBYES 3 1 NS NPS 0 0 No paper found, PISA says monomer -- Annotation transfered from 1ep5 1ep9 NO 3 3 C3 C3 11237854 11237854 Paper says trimer -- Annotation transfered from 1oth 1epa PROBYES 2 1 C2 NPS 8069623 8069623 8761444 says RABPs are monomeric - and PISA says dimer. Email was sent to the authors. Answer: it is very likely a monomer in solution -- Annotation transfered from 1epb 1epb PROBYES 2 1 C2 NPS 8069623 8069623 8761444 says RABPs are monomeric - and PISA says dimer. Email was sent to the authors. Answer: it is very likely a monomer in solution 1epl PROBNOT 1 1 NPS NPS 7703859 7703859 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1epm PROBNOT 1 1 NPS NPS 7703859 7703859 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1epn PROBNOT 1 1 NPS NPS 7703859 7703859 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1epo PROBNOT 1 1 NPS NPS 1304340 1304340 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1epp PROBNOT 1 1 NPS NPS 8254610 8254610 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1epq PROBNOT 1 1 NPS NPS 8254610 8254610 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1epr PROBNOT 1 1 NPS NPS 7703859 7703859 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1eps PROBNOT 1 1 NPS NPS 11607190 11607190 SP says monomer -- Annotation transfered from 1q36 1epy NO 1 1 NPS NPS 10835104 10835104 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1epz NO 2 2 C2 C2 10827167 10827167 Interface geometry conserved with 1rtv (49%) -- Annotation transfered from 1ep0 1eq4 NO 1 1 NPS NPS 11015217 11015217 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1eq5 NO 1 1 NPS NPS 11015217 11015217 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1eq9 NO 2 2 C2 C2 10801356 10801356 Like bovine aC, C1 migrates on SDS-PAGE as a very stable dimer of 48 kDa 1eqa YES 2 1 C2 NPS 10377383 10377383 SP and PISA say monomer -- Annotation transfered from 3mct 1eqe NO 1 1 NPS NPS 11015217 11015217 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1eqg NO 2 2 C2 C2 11318639 11318639 -- Annotation transfered from 1cqe 1eqh NO 2 2 C2 C2 11318639 11318639 -- Annotation transfered from 1cqe 1eqm PROBNOT 1 1 NPS NPS 11546767 11546767 EcoCyc & SP say monomer. 1eqq NO 4 4 D2 D2 10731701 10731701 Structure shown in paper -- Annotation transfered from 1qvc 1eqr YES 4 2 C2 C2 10873442 10873442 Interface geometry conserved with 1g51 (48%) 1eqt PROBNOT 2 2 C2 C2 -1 0 Paper implies it is a dimer 1equ NO 2 2 C2 C2 9927655 9927655 Paper says dimer -- Annotation transfered from 3dhe 1eqv NO 1 1 NPS NPS 0 0 Paper says monomeric -- Annotation transfered from 1ena 1er8 PROBNOT 1 1 NPS NPS 6381096 6381096 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1erb NO 1 1 NPS NPS 8227049 8227049 Circulating in the plasma, the monomeric RBP molecule (21 kDa) is found associated in a macromolecular complex with the tetrameric thyroxine-binding transthyretin (55 kDa). The formation of the RBP–transthyretin complex is believed to prevent filtration through renal glomeruli of the relatively small RBP molecule. -- Annotation transfered from 1kt5 1ere_1 NO 2 2 C2 C2 9338790 9338790 paper says dimer - automatic transfer from 1err 1ere_2 NO 2 2 C2 C2 9338790 9338790 paper says dimer - automatic transfer from 1err 1ere_3 NO 2 2 C2 C2 9338790 9338790 paper says dimer - automatic transfer from 1err 1erk PROBNOT 1 1 NPS NPS 8107865 8107865 -- Annotation transfered from 4erk 1erm PROBNOT 1 1 NPS NPS 10820001 10820001 EcoCyc says monomer -- Annotation transfered from 1jwp 1ero PROBNOT 1 1 NPS NPS 10820001 10820001 EcoCyc says monomer -- Annotation transfered from 1jwp 1erq PROBNOT 1 1 NPS NPS 10820001 10820001 EcoCyc says monomer -- Annotation transfered from 1jwp 1err NO 2 2 C2 C2 9338790 9338790 paper says dimer 1ert PROBNOT 2 2 C2 C2 8805557 8805557 SP says dimer, paper too, interface geometry conserved with 1nsw (36%) - monomer dimer equilibrium -- Annotation transfered from 1aiu 1eru PROBNOT 2 2 C2 C2 8805557 8805557 SP says dimer, paper too, interface geometry conserved with 1nsw (36%) - monomer dimer equilibrium -- Annotation transfered from 1aiu 1erv PROBNOT 2 2 C2 C2 8805557 8805557 SP says dimer, paper too, interface geometry conserved with 1nsw (36%) - monomer dimer equilibrium -- Annotation transfered from 1aiu 1erw PROBNOT 2 2 C2 C2 8805557 8805557 SP says dimer, paper too, interface geometry conserved with 1nsw (36%) - monomer dimer equilibrium -- Annotation transfered from 1aiu 1erz NA 4 4 D2 D2 10903946 10903946 Paper says: From biochemical characterization studies of DCase it has been reported that DCase forms a dimer or a trimer. In the crystal structure, DCase exists as an associated homotetramer 1es1 PROBNOT 1 1 NPS NPS 10842340 10842340 Oligomeric state not mentioned - PISA says monomer -- Annotation transfered from 1lqx 1es2 PROBNOT 1 1 NPS NPS 12627955 12627955 1es3 PROBNOT 1 1 NPS NPS 12627955 12627955 -- Annotation transfered from 1es2 1es4 PROBNOT 1 1 NPS NPS 12627955 12627955 -- Annotation transfered from 1es2 1es5 PROBNOT 1 1 NPS NPS 0 0 -- Annotation transfered from 1es2 1es6 NO 1 1 NPS NPS 10944105 10944105 Monomer, but C-terminal domain forms octameric rings when cleaved. The octameric form is found in 1h2c and 1h2d. 1esa PROBNOT 1 1 NPS NPS 8049229 8049229 -- Annotation transfered from 1c1m 1esb PROBNOT 1 1 NPS NPS 8049229 8049229 -- Annotation transfered from 1c1m 1esc PROBNOT 2 2 C2 C2 7773790 7773790 Look at the paper but for the moment I rely on PISA prediction 1esd PROBYES 1 2 NPS C2 7773790 0 Look at the paper, but the correction is made based on PISA prediction that it is a dimer 1ese PROBYES 1 2 NPS C2 7773790 0 Look at the paper, but the correction is made based on PISA prediction that it is a dimer -- Annotation transfered from 1esd 1esi PROBNOT 1 1 NPS NPS 0 0 -- Annotation transfered from 1es2 1esj NO 3 3 C3 C3 10891066 10891066 Interface geometry conserved with 1v8a (43%) -- Annotation transfered from 1esq 1eso NO 1 1 NPS NPS 9405149 9405149 Paper says monomeric 1esq NO 3 3 C3 C3 10891066 10891066 Interface geometry conserved with 1v8a (43%) 1est PROBNOT 1 1 NPS NPS 628010 628010 -- Annotation transfered from 1c1m 1esu PROBNOT 1 1 NPS NPS 15299797 0 EcoCyc says monomer -- Annotation transfered from 1jwp 1et0 YES 1 2 NPS C2 10876155 10876155 said in the paper 1et5 NO 3 3 C3 C3 10811642 10811642 -- Annotation transfered from 1as7 1et7 NO 3 3 C3 C3 10811642 10811642 -- Annotation transfered from 1as7 1et8 NO 3 3 C3 C3 10811642 10811642 -- Annotation transfered from 1as7 1eta PROBYES 2 4 C2 D2 8428915 8428915 All dimers similar to that one are found to be tetramers by PISA. Because the native structure is tetrameric, dimer are certainly mistakes -- Annotation transfered from 1bmz 1etb PROBYES 2 4 C2 D2 8428915 8428915 All dimers similar to that one are found to be tetramers by PISA. Because the native structure is tetrameric, dimer are certainly mistakes -- Annotation transfered from 1bmz 1etj_1 PROBNOT 1 1 NPS NPS 9100002 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1etj_2 PROBNOT 1 1 NPS NPS 9100002 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1etj_3 PROBNOT 1 1 NPS NPS 9100002 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1etj_4 PROBNOT 1 1 NPS NPS 9100002 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1eue_1 PROBNOT 1 1 NPS NPS 11197480 9484218 BU changed since last release and is now corrected - Oligomeric state not mentioned - PISA says monomer - automaticaly inferred from 1awp 1eue_2 PROBNOT 1 1 NPS NPS 11197480 9484218 BU changed since last release and is now corrected - Oligomeric state not mentioned - PISA says monomer - automaticaly inferred from 1awp 1euf PROBNOT 1 1 NPS NPS 10944388 10944388 SP says monomer 1euh NO 4 4 D2 D2 10388564 10388564 Interface geometry conserved with 1uxr (35%) -- Annotation transfered from 1qi6 1euj_1 NO 1 1 NPS NPS 10852899 11157763 Monomer mimics the dimer -- very nice interesting example for a letter to the editor. - automatic transfer from 1e7z 1euj_2 NO 1 1 NPS NPS 10852899 11157763 Monomer mimics the dimer -- very nice interesting example for a letter to the editor. - automatic transfer from 1e7z 1eum NO 24 24 Octa Octa 11254384 11254384 Interface geometry conserved with 1lb3 (23%) 1eup PROBNOT 1 1 NPS NPS 10716705 10716705 Paper does not mention oligomer - PISA says monomer - many instances of monomers -- Annotation transfered from 1egy 1ev4 YES 4 2 C2 C2 11119643 11119643 glutathione S-transferases are functional dimers. -- Annotation transfered from 1ev9 1ev5 NO 2 2 C2 C2 10841779 10841779 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1ev8 NO 2 2 C2 C2 10841779 10841779 SP and EcoCyc say dimer 1ev9 YES 4 2 C2 C2 11119643 11119643 glutathione S-transferases are functional dimers. 1eve PROBNOT 1 1 NPS NPS 10368299 10368299 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1evf NO 2 2 C2 C2 10841779 10841779 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1evg NO 2 2 C2 C2 10841779 10841779 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1evh PROBNOT 1 1 NPS NPS 10338211 10338211 Nothing said about a dimer, and PISA says monomer 1evj_1 PROBYES 2 4 C2 D2 11099381 11705375 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - Interface geometry conserved with 1tlt (20%) - automaticaly inferred from 1h6b 1evj_2 PROBYES 2 4 C2 D2 11099381 11705375 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - Interface geometry conserved with 1tlt (20%) - automaticaly inferred from 1h6b 1evq PROBNOT 1 1 NPS NPS 11061974 11061974 Paper says: the protein, a monomeric B-type carboxylesterase of about 34 kDa, was purified and characterized. -- Annotation transfered from 1qz3 1evu NO 2 2 C2 C2 0 0 Paper says dimer -- but wrong reconstruction, PISa get the good interface but makes a tetramer -- Annotation transfered from 1ggt 1ew3 NO 2 2 C2 C2 10787420 10787420 Equ c 1 is found to form a dimer in the crystal, in agreement with gel filtration experiments in solution at neutral pH 1ewh_1 PROBNOT 1 1 NPS NPS 10924110 10869174 BU changed since last release and is now corrected - Paper says: distorted proper 2-fold rotation. This may represent the dimeric relation of the monomers in situ; however, the heme orientation suggested by this model is not consistent with previous EPR measurements on oriented membranes. - automaticaly inferred from 1cfm 1ewh_2 PROBNOT 1 1 NPS NPS 10924110 10869174 BU changed since last release and is now corrected - Paper says: distorted proper 2-fold rotation. This may represent the dimeric relation of the monomers in situ; however, the heme orientation suggested by this model is not consistent with previous EPR measurements on oriented membranes. - automaticaly inferred from 1cfm 1ewh_3 PROBNOT 1 1 NPS NPS 10924110 10869174 BU changed since last release and is now corrected - Paper says: distorted proper 2-fold rotation. This may represent the dimeric relation of the monomers in situ; however, the heme orientation suggested by this model is not consistent with previous EPR measurements on oriented membranes. - automaticaly inferred from 1cfm 1ewl NO 1 1 NPS NPS 0 0 The enzyme is a monomeric glycoprotein -- Annotation transfered from 1me4 1ewm NO 1 1 NPS NPS 0 0 The enzyme is a monomeric glycoprotein -- Annotation transfered from 1me4 1ewo NO 1 1 NPS NPS 0 0 The enzyme is a monomeric glycoprotein -- Annotation transfered from 1me4 1ewp NO 1 1 NPS NPS -1 0 The enzyme is a monomeric glycoprotein -- Annotation transfered from 1me4 1ewx PROBNOT 1 1 NPS NPS 11347894 11347894 Paper says that protein is in an oxidized state (no S-S). -- Annotation transfered from 1ezk 1ewy_2 NO 1 1 NPS NPS 11053838 8890910 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) - automatic transfer from 1que 1ewz_1 NO 2 2 C2 C2 -1 11453693 Paper says dimer - interface geometry conserved with 1k38 (37%) - automatic transfer from 1h8z 1ewz_2 NO 2 2 C2 C2 -1 11453693 Paper says dimer - interface geometry conserved with 1k38 (37%) - automatic transfer from 1h8z 1ex0 NO 2 2 C2 C2 0 0 Paper says dimer -- but wrong reconstruction, PISa get the good interface but makes a tetramer -- Annotation transfered from 1ggt 1ex3 NA 1 1 NPS NPS 10873462 3980476 They explain in the paper (3980476) that chymotrypsin can form an asymetric dimer, but can also be found as a monomer in particular conditions. Here PISA says monomer. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). 1ex6 PROBYES 2 1 NS NPS 11243817 11243817 Paper says nothing, SP and PISA say monomer 1ex7 PROBNOT 1 1 NPS NPS 11243817 11243817 Paper says nothing, SP and PISA say monomer 1ex8 PROBNOT 1 1 NPS NPS 11311059 11311059 EcoCyc & SP say monomer. -- Annotation transfered from 1eqm 1ex9 PROBNOT 1 1 NPS NPS 10893416 10893416 Paper says nothing, PISA says monomer and related prots are monomeric 1exa PROBNOT 1 1 NPS NPS 10841540 10841540 Do not talk about monomer nor dimer - PISA says monomer, they all crystallize as monomers so I assume they are really monomers. 1exb NO 8 8 C4 C4 10884227 10884227 Interface geometry conserved with 3kvt (42%) 1exm NO 1 1 NPS NPS -1 9838020 EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa 1exp PROBNOT 1 1 NPS NPS 8564541 8564541 Apparently the family doesnt form dimers but there is no clear evidence. 1exr NO 1 1 NPS NPS 10966818 10966818 1exs NO 2 2 C2 C2 11856834 11856834 Sort of domain swapped 1exv NO 2 2 C2 C2 10980448 10980448 -- Annotation transfered from 1fc0 1exx PROBNOT 1 1 NPS NPS 10841540 10841540 Do not talk about monomer nor dimer - PISA says monomer, they all crystallize as monomers so I assume they are really monomers. -- Annotation transfered from 1exa 1ey0 NO 1 1 NPS NPS 11023780 11023780 Paper says monomeric -- Annotation transfered from 1ena 1ey3 NO 6 6 D3 D3 11851409 11851409 Everyone says hexamer! -- Annotation transfered from 2dub 1ey4 NO 1 1 NPS NPS 11023780 11023780 Paper says monomeric -- Annotation transfered from 1ena 1ey5 NO 1 1 NPS NPS 11023780 11023780 Paper says monomeric -- Annotation transfered from 1ena 1ey6 NO 1 1 NPS NPS 11023780 11023780 Paper says monomeric -- Annotation transfered from 1ena 1ey7 NO 1 1 NPS NPS 11023780 11023780 Paper says monomeric -- Annotation transfered from 1ena 1ey8 NO 1 1 NPS NPS 11023780 11023780 Paper says monomeric -- Annotation transfered from 1ena 1ey9 NO 1 1 NPS NPS 11023780 11023780 Paper says monomeric -- Annotation transfered from 1ena 1eya NO 1 1 NPS NPS 11023780 11023780 Paper says monomeric -- Annotation transfered from 1ena 1eyc NO 1 1 NPS NPS 11023780 11023780 Paper says monomeric -- Annotation transfered from 1ena 1eyd NO 1 1 NPS NPS 11023780 11023780 Paper says monomeric -- Annotation transfered from 1ena 1eyg_1 PROBYES 2 4 C2 D2 10932248 10731701 BU changed since last release and is now incorrect - Structure shown in paper - automaticaly inferred from 1qvc 1eyg_2 PROBYES 2 4 C2 D2 10932248 10731701 BU changed since last release and is now incorrect - Structure shown in paper - automaticaly inferred from 1qvc 1eyi NO 4 4 D2 D2 10913263 10913263 1eyj NO 4 4 D2 D2 10913263 10913263 -- Annotation transfered from 1eyi 1eyk NO 4 4 D2 D2 10913263 10913263 -- Annotation transfered from 1eyi 1eym NO 2 1 C2 NPS 10852943 10852943 Carries one mutation (F36M) that transforms it into an inducible dimer. Isnt that so interesting? It thus also shows that it can be very simple to form a heterointerfaces, and that a high proportion of supposedly errors in the BU can reflect a potential high affinity (given that 1/2 mutations are introduced) - very nice example! 1eyn PROBNOT 1 1 NPS NPS 10823915 10823915 MurA crystallizes from PEG 20000 as a monomeric species. 1eyt PROBNOT 1 1 NPS NPS 11095707 11095707 The protein seem to be in a monomer dimer equilibrium (12077426 EPR and NMR studies have shown that HiPIPs might dimerize in the solution through their hydrophobic surfaces, a discovery that has led to important insights regarding the electron-transfer pathway) -- Annotation transfered from 1iua 1eyv NO 2 2 C2 C2 10881194 10881194 Paper says: unlike the E. coli homolog, M. tuberculosis NusB is dimeric both in solution and in the crystal. 1eyz NO 2 2 C2 C2 10913290 10913290 SP and paper say dimer - Interface geometry conserved with 1b6r (24%) 1ez1 NO 2 2 C2 C2 10913290 10913290 SP and paper say dimer - Interface geometry conserved with 1b6r (24%) -- Annotation transfered from 1eyz 1ez4 NO 4 4 D2 D2 11807949 11807949 Paper say tetrameric - In contrast to other LDH, allostery is absent. 1ez6 NO 1 1 NPS NPS 11023780 11023780 Paper says monomeric -- Annotation transfered from 1ena 1ez8 NO 1 1 NPS NPS 11023780 11023780 Paper says monomeric -- Annotation transfered from 1ena 1ez9_1 PROBNOT 1 1 NPS NPS 11790091 12794084 EcoCyc says monomer - automatic transfer from 1nl5 1ez9_2 PROBNOT 1 1 NPS NPS 11790091 12794084 EcoCyc says monomer - automatic transfer from 1nl5 1ezk PROBNOT 1 1 NPS NPS 11347894 11347894 Paper says that protein is in an oxidized state (no S-S). 1ezl PROBYES 4 1 D2 NPS 10880975 10880975 This is hard to believe but it seems that azurin is a monomeric protein! -- Annotation transfered from 5azu 1ezq PROBNOT 2 2 NPS NPS 10966741 10966741 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1ezr NO 4 4 D2 D2 10409664 10409664 Interface geometry conserved with 1mas (78%) 1ezv NO 20 20 NPS NPS 10873857 10873857 Interface geometry of the dimerization conserved with 1l0l (37%) 1ezw NO 4 4 D2 D2 10891279 10891279 Interface geometry conserved with 1m41 (21%) 1ezz NO 12 12 D3 D3 10891088 10891088 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1f06_1 PROBYES 1 2 NPS C2 11106178 9521647 BU changed since last release and is now incorrect - Paper says dimer - automaticaly inferred from 2dap 1f06_2 PROBYES 1 2 NPS C2 11106178 9521647 BU changed since last release and is now incorrect - Paper says dimer - automaticaly inferred from 2dap 1f07 PROBYES 4 2 NS C2 10891279 10891279 Paper says dimer 1f08 PROBNOT 2 2 C2 C2 10949036 10949036 PAper says dimer 1f09 NO 1 1 NPS NPS 10926499 10926499 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1f0b NO 1 1 NPS NPS 10926499 10926499 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1f0m PROBNOT 1 1 NPS NPS 10601296 10601296 Paper says monomeric 1f0n NO 1 1 NPS NPS 11254389 11254389 Say monomeric in paper 1f0p NO 1 1 NPS NPS 11254389 11254389 Say monomeric in paper -- Annotation transfered from 1f0n 1f0q NO 1 1 NPS NPS 10882732 10882732 Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. -- Annotation transfered from 1jam 1f0r PROBNOT 2 2 NPS NPS 10966741 10966741 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1f0s PROBNOT 2 2 NPS NPS 10966741 10966741 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1f0t PROBNOT 1 1 NPS NPS 10966741 10966741 -- Annotation transfered from 1az8 1f0u PROBNOT 1 1 NPS NPS 10966741 10966741 -- Annotation transfered from 1az8 1f0v_1 PROBNOT 1 1 NPS NPS 11224563 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1f0v_2 PROBNOT 1 1 NPS NPS 11224563 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1f0v_3 PROBNOT 1 1 NPS NPS 11224563 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1f0v_4 PROBNOT 1 1 NPS NPS 11224563 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1f0w NO 1 1 NPS NPS 10957630 10957630 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1f10 NO 1 1 NPS NPS 10957630 10957630 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1f13 NO 2 2 C2 C2 9515726 9515726 Paper says dimer -- but wrong reconstruction, PISa get the good interface but makes a tetramer -- Annotation transfered from 1ggt 1f18 NO 2 2 C2 C2 0 0 SOD is a dimer -- Annotation transfered from 2jcw 1f1a NO 2 2 C2 C2 0 0 SOD is a dimer -- Annotation transfered from 2jcw 1f1b NO 12 12 D3 D3 10891088 10891088 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1f1c NO 2 2 C2 C2 11478889 11478889 Paper says: Finally, the cytochrome c-549 dimer we observe can be readily fit into the recently described model of cyanobacterial photosystem II. - interface geometry conserved with 1e29 (48%) 1f1d NO 2 2 C2 C2 0 0 SOD is a dimer -- Annotation transfered from 2jcw 1f1f NA 1 1 NPS NPS 11478889 11478889 SP says monomner for 1kib (98% id), paper says elutes as a dimer. Might be an equilibrium. -- interesting for evolution study! 1f1g_1 NO 2 2 C2 C2 0 10026301 SOD is a dimer - automatic transfer from 2jcw 1f1g_2 NO 2 2 C2 C2 0 10026301 SOD is a dimer - automatic transfer from 2jcw 1f1g_3 NO 2 2 C2 C2 0 10026301 SOD is a dimer - automatic transfer from 2jcw 1f1h NO 12 12 D6 D6 11329256 11329256 Salmonella typhimurium GS has a molecular mass of 620 kDa and is a dodecamer with 622 symmetry 1f1o NA 1 4 NPS D2 10926519 10926519 Too low resolution to reconstruct the tetramer - but paper says it is tetrameric 1f1r NO 4 4 D2 D2 15028678 15028678 Interface geometry conserved with 1mpy (25%) -- Annotation transfered from 1f1v 1f1u NO 4 4 D2 D2 15028678 15028678 Interface geometry conserved with 1mpy (25%) -- Annotation transfered from 1f1v 1f1v NO 4 4 D2 D2 15028678 15028678 Interface geometry conserved with 1mpy (25%) 1f1w NO 1 1 NPS NPS 10911998 10911998 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1f1x NO 4 4 D2 D2 15028678 15028678 Interface geometry conserved with 1mpy (25%) 1f21 PROBNOT 1 1 NPS NPS 11106164 11106164 SP says monomer 1f24 PROBNOT 1 1 NPS NPS 11132616 0 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer -- Annotation transfered from 1cmj 1f25 PROBNOT 1 1 NPS NPS 11132616 0 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer -- Annotation transfered from 1cmj 1f26 PROBNOT 1 1 NPS NPS 11132616 0 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer -- Annotation transfered from 1cmj 1f28_1 NO 2 2 C2 C2 11358692 10529228 Paper says dimer - automatic transfer from 1ci7 1f28_2 NO 2 2 C2 C2 11358692 10529228 Paper says dimer - automatic transfer from 1ci7 1f29_1 NO 1 1 NPS NPS 10997902 1526455 The enzyme is a monomeric glycoprotein - automatic transfer from 1me4 1f29_2 NO 1 1 NPS NPS 10997902 1526455 The enzyme is a monomeric glycoprotein - automatic transfer from 1me4 1f29_3 NO 1 1 NPS NPS 10997902 1526455 The enzyme is a monomeric glycoprotein - automatic transfer from 1me4 1f2a NO 1 1 NPS NPS 10997902 10997902 The enzyme is a monomeric glycoprotein -- Annotation transfered from 1me4 1f2b NO 1 1 NPS NPS 10997902 10997902 The enzyme is a monomeric glycoprotein -- Annotation transfered from 1me4 1f2c NO 1 1 NPS NPS 10997902 10997902 The enzyme is a monomeric glycoprotein -- Annotation transfered from 1me4 1f2f NO 1 1 NPS NPS 10911998 10911998 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1f2k_1 PROBNOT 1 1 NPS NPS 0 8078936 SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio - automatic transfer from 2acg 1f2k_2 PROBNOT 1 1 NPS NPS 0 8078936 SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio - automatic transfer from 2acg 1f2l PROBYES 4 2 C2 C2 10770945 10770945 CDF has not been found to dimerize in solution at any concentration. However, this does not rule out dimer formation in vivo, in the presence of the receptor and other participating molecules - interesting 1f2m NO 1 1 NPS NPS 0 0 Paper says monomeric -- Annotation transfered from 1ena 1f2o PROBNOT 1 1 NPS NPS 11484227 11484227 SwissProt says monomer 1f2p PROBNOT 1 1 NPS NPS 11484227 11484227 SwissProt says monomer -- Annotation transfered from 1f2o 1f2v NO 2 2 C2 C2 11470433 0 Interface geometry conserved with 1f2v (43%) 1f2w PROBNOT 1 1 NPS NPS 11015219 11015219 9000633 says monomeric -- Annotation transfered from 1uga 1f2y NO 1 1 NPS NPS 0 0 Paper says monomeric -- Annotation transfered from 1ena 1f2z NO 1 1 NPS NPS 0 0 Paper says monomeric -- Annotation transfered from 1ena 1f30 YES 12 12 NS Tetr 0 0 BU changed since last release and is now incorrect - Interface geometry conserved with 1o9r (55%) 1f33 YES 12 12 NS Tetr 0 0 Interface geometry conserved with 1o9r (55%) 1f38 NO 4 4 D2 D2 12429089 12429089 Paper says: Static light-scattering measurements give a molecular weight of 81 kDa for MT0146/CbiT, compared with a protomer molecular weight of 21 kDa, showing that the protein forms a tetramer in solution. -- Annotation transfered from 1l3c 1f3a NO 2 2 C2 C2 11027134 11027134 glutathione S-transferases are functional dimers. 1f3b NO 2 2 C2 C2 11027134 11027134 glutathione S-transferases are functional dimers. -- Annotation transfered from 1f3a 1f3f NO 6 6 D3 D3 10899107 10899107 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1f3g PROBNOT 3 3 C3 C3 1961703 1961703 9405042 says: IIAGlc aggregates in solution; dimeric, trimeric, and hexameric forms of IIAGlc have been observed in gel filtration and immunoelectrophoretic studies (40). The dimeric and trimeric crystal contact interactions shown in Figure 2b,c are likely to represent the states observed in these studies. 1f3h NO 2 2 C2 C2 10876248 10876248 SP and paper say dimer -- Annotation transfered from 1e31 1f3l YES 1 2 NPS C2 10899106 10899106 Interface geometry conserved with 1or8 (50% id) 1f3o YES 2 1 C2 NPS 11402022 11402022 According to 12150914 this dimer is wrong. Non native state. 1f3p PROBNOT 1 1 NPS NPS 11090282 11090282 They observe a dimer in solution, but similarly to 1gv4 it must be weak and a monomer-dimer equilibrium probably exists 1f3w_1 PROBNOT 4 4 D2 D2 11563914 8193145 BU changed since last release and is now corrected - 15299671 says tetramer - automaticaly inferred from 1pkn 1f3w_2 PROBNOT 4 4 D2 D2 11563914 8193145 BU changed since last release and is now corrected - 15299671 says tetramer - automaticaly inferred from 1pkn 1f3x_1 PROBNOT 4 4 D2 D2 11563914 8193145 BU changed since last release and is now corrected - 15299671 says tetramer - automaticaly inferred from 1pkn 1f3x_2 PROBNOT 4 4 D2 D2 11563914 8193145 BU changed since last release and is now corrected - 15299671 says tetramer - automaticaly inferred from 1pkn 1f3z YES 2 2 C2 C2 9405042 9405042 Paper says: IIAGlc aggregates in solution; dimeric, trimeric, and hexameric forms of IIAGlc have been observed in gel filtration and immunoelectrophoretic studies (40). The dimeric and trimeric crystal contact interactions shown in Figure 2b,c are likely to represent the states observed in these studies. -- but wrong dimer. The right one is 2f3g and PISA does not find it ... 1f41 NO 4 4 D2 D2 10986125 10986125 transthyretin is tetrameric -- Annotation transfered from 1fh2 1f44 NO 3 3 C3 C3 11601846 11601846 Paper says: To our knowledge, this is the first direct demonstration of quasi-equivalence in both the assembly and function of an oligomeric enzyme. -- very nice: C3 --> C4 transition at 99% des id! 1f46 PROBYES 2 1 NS NPS 10880432 10880432 No oligomer mentioned - PISA says monomer 1f47 PROBNOT 1 1 NPS NPS 10880432 10880432 BU changed since last release and is now corrected - No oligomer mentioned - PISA says monomer - automaticaly inferred from 1f46 1f4b NO 2 2 C2 C2 10944209 10944209 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1f4c NO 2 2 C2 C2 10944209 10944209 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1f4d NO 2 2 C2 C2 10944209 10944209 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1f4e NO 2 2 C2 C2 10944209 10944209 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1f4f NO 2 2 C2 C2 10944209 10944209 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1f4g NO 2 2 C2 C2 10944209 10944209 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1f4j NO 4 4 D2 D2 11134921 11134921 Interface geometry conserved with 1mqf (52% id) -- Annotation transfered from 1dgg 1f4l PROBYES 2 1 NS NPS 11243794 12946347 Paper says: Crystals of a monomeric fragment of Escherichia coli methionyl-tRNA synthetase (551 N-terminal residues) have been used to determine the 3D-structure of the free enzyme 1f4m_1 NO 2 2 C2 C2 11188696 11188696 Rop is a homodimeric RNA-binding protein (Polisky, 1988) - automatic transfer from 1f4n 1f4m_2 NO 2 2 C2 C2 11188696 11188696 Rop is a homodimeric RNA-binding protein (Polisky, 1988) - automatic transfer from 1f4n 1f4m_3 NO 2 2 C2 C2 11188696 11188696 Rop is a homodimeric RNA-binding protein (Polisky, 1988) - automatic transfer from 1f4n 1f4n NO 2 2 C2 C2 11188696 11188696 Rop is a homodimeric RNA-binding protein (Polisky, 1988) 1f4o NO 2 2 C2 C2 10903868 10903868 -- Annotation transfered from 1k94 1f4p PROBNOT 1 1 NPS NPS 11264581 11264581 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins 1f4q NO 2 2 C2 C2 10903868 10903868 -- Annotation transfered from 1k94 1f4v_1 PROBNOT 1 1 NPS NPS 11135671 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 1f4v_2 PROBNOT 1 1 NPS NPS 11135671 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 1f4v_3 PROBNOT 1 1 NPS NPS 11135671 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 1f4z NO 3 3 C3 C3 10903866 10903866 SP says trimer -- Annotation transfered from 2brd 1f50 NO 3 3 C3 C3 10903866 10903866 SP says trimer -- Annotation transfered from 2brd 1f52 NO 12 12 D6 D6 11329256 11329256 Salmonella typhimurium GS has a molecular mass of 620 kDa and is a dodecamer with 622 symmetry -- Annotation transfered from 1f1h 1f5b NO 1 1 NPS NPS 11875515 11875515 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1f5c NO 1 1 NPS NPS 11875515 11875515 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1f5k PROBNOT 1 1 NPS NPS 10926521 10926521 -- Annotation transfered from 1owd 1f5l PROBNOT 1 1 NPS NPS 10926521 10926521 -- Annotation transfered from 1owd 1f5o_1 PROBYES 2 1 C2 NPS 11340069 4032476 BU changed since last release and is now incorrect - SP says: Monomer at high oxygen tension and high pH and dimeric at low oxygen tension and lower pH - induced dimerization - automaticaly inferred from 2lhb 1f5o_2 PROBYES 2 1 C2 NPS 11340069 4032476 BU changed since last release and is now incorrect - SP says: Monomer at high oxygen tension and high pH and dimeric at low oxygen tension and lower pH - induced dimerization - automaticaly inferred from 2lhb 1f5o_3 PROBYES 2 1 C2 NPS 11340069 4032476 BU changed since last release and is now incorrect - SP says: Monomer at high oxygen tension and high pH and dimeric at low oxygen tension and lower pH - induced dimerization - automaticaly inferred from 2lhb 1f5p_1 PROBYES 2 1 C2 NPS 11340069 4032476 BU changed since last release and is now incorrect - SP says: Monomer at high oxygen tension and high pH and dimeric at low oxygen tension and lower pH - induced dimerization - automaticaly inferred from 2lhb 1f5p_2 PROBYES 2 1 C2 NPS 11340069 4032476 BU changed since last release and is now incorrect - SP says: Monomer at high oxygen tension and high pH and dimeric at low oxygen tension and lower pH - induced dimerization - automaticaly inferred from 2lhb 1f5p_3 PROBYES 2 1 C2 NPS 11340069 4032476 BU changed since last release and is now incorrect - SP says: Monomer at high oxygen tension and high pH and dimeric at low oxygen tension and lower pH - induced dimerization - automaticaly inferred from 2lhb 1f5t PROBYES 4 2 C2 C2 10956029 7568230 BU changed since last release and is now incorrect - Interface geometry conserved down to 30% with 1on1 - automaticaly inferred from 1dpr 1f5w NO 2 2 C2 C2 11080637 11080637 Paper says dimer 1f5z NO 4 4 D2 D2 11031117 11031117 Paper says tetramer -- Annotation transfered from 1f6k 1f61 NO 4 4 D2 D2 10932251 10932251 Interface geometry conserved with 1s2u (25%) -- strange though: protein is much bigger! - automatic transfer from 1f8i 1f63 NO 1 1 NPS NPS 10049310 10049310 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1f65 NO 1 1 NPS NPS 10049310 10049310 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1f6b NO 2 2 C2 C2 11739406 11739406 The protein had a native apparent molecular mass of 43.6 kD corresponding to a dimer 1f6k NO 4 4 D2 D2 11031117 11031117 Paper says tetramer 1f6l NO 2 2 C2 C2 12217656 12217656 Paper says dimer 1f6p NO 4 4 D2 D2 11031117 11031117 Paper says tetramer -- Annotation transfered from 1f6k 1f6r YES 6 1 D3 NPS 10896943 10896943 Lactose synthase (LS) is a heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA). 1f6s YES 6 1 NS NPS 10896943 10896943 Lactose synthase (LS) is a heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA). 1f6t NO 6 6 D3 D3 10899107 10899107 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1f6w PROBNOT 1 1 NPS NPS 11045623 11045623 Paper says nothing, PISA says monomer 1f73 NO 4 4 D2 D2 11031117 11031117 Paper says tetramer -- Annotation transfered from 1f6k 1f74 NO 4 4 D2 D2 11031117 11031117 Paper says tetramer -- Annotation transfered from 1f6k 1f7a NO 2 2 C2 C2 10966816 10966816 -- Annotation transfered from 1ajx 1f7b NO 4 4 D2 D2 11031117 11031117 Paper says tetramer -- Annotation transfered from 1f6k 1f7d_1 PROBNOT 3 3 C3 C3 10957629 10957629 Paper says: The P63 crystal form contains independent trimers on the 63 screw and threefold axes. - automatic transfer from 1f7o 1f7d_2 PROBNOT 3 3 C3 C3 10957629 10957629 Paper says: The P63 crystal form contains independent trimers on the 63 screw and threefold axes. - automatic transfer from 1f7o 1f7k_1 PROBNOT 3 3 C3 C3 10957629 10957629 Paper says: The P63 crystal form contains independent trimers on the 63 screw and threefold axes. - automatic transfer from 1f7o 1f7k_2 PROBNOT 3 3 C3 C3 10957629 10957629 Paper says: The P63 crystal form contains independent trimers on the 63 screw and threefold axes. - automatic transfer from 1f7o 1f7n_1 PROBNOT 3 3 C3 C3 10957629 10957629 Paper says: The P63 crystal form contains independent trimers on the 63 screw and threefold axes. - automatic transfer from 1f7o 1f7n_2 PROBNOT 3 3 C3 C3 10957629 10957629 Paper says: The P63 crystal form contains independent trimers on the 63 screw and threefold axes. - automatic transfer from 1f7o 1f7o PROBNOT 3 3 C3 C3 10957629 10957629 Paper says: The P63 crystal form contains independent trimers on the 63 screw and threefold axes. 1f7p PROBNOT 3 3 C3 C3 10957629 10957629 Paper says: The P63 crystal form contains independent trimers on the 63 screw and threefold axes. -- Annotation transfered from 1f7o 1f7q PROBNOT 3 3 C3 C3 10957629 10957629 Paper says: The P63 crystal form contains independent trimers on the 63 screw and threefold axes. -- Annotation transfered from 1f7o 1f7r PROBNOT 3 3 C3 C3 10957629 10957629 Paper says: The P63 crystal form contains independent trimers on the 63 screw and threefold axes. -- Annotation transfered from 1f7o 1f82 PROBNOT 1 1 NPS NPS 10932255 10932255 Paper says nothing, PISA says monomer 1f86 PROBYES 2 4 C2 D2 11243784 11243784 All dimers similar to that one are found to be tetramers by PISA. Because the native structure is tetrameric, dimer are certainly mistakes -- Annotation transfered from 1bmz 1f89 NO 2 2 C2 C2 12833551 12833551 Paper says: The protein folds as a four-layer alpha-beta beta-alpha sandwich and exists as a dimer in the crystal and in solution. 1f8a PROBYES 1 2 NPS C2 10932246 10932246 Dimer according to PISA, and also according to me given the interface between the 2 polyp. chains in the ASU. But apparently no biochemical evidence. 1f8f NO 4 4 D2 D2 0 0 1f8i NO 4 4 D2 D2 10932251 10932251 Interface geometry conserved with 1s2u (25%) -- strange though: protein is much bigger! 1f8m NO 4 4 D2 D2 10932251 10932251 Interface geometry conserved with 1s2u (25%) -- strange though: protein is much bigger! - automatic transfer from 1f8i 1f8q PROBNOT 1 1 NPS NPS 11451448 11451448 No info in papers, PISA says monomer -- Annotation transfered from 1aha 1f8w NO 4 4 D2 D2 10956025 10956025 1f92 PROBNOT 1 1 NPS NPS 10926521 10926521 -- Annotation transfered from 1owd 1f94 NA 1 1 NPS NPS 11053837 11053837 Ask the persons who work with it 1f97 YES 1 2 NPS C2 11500366 11500366 Interface geometry conserved with 1nbq (60% id) 1f98 PROBNOT 1 1 NPS NPS 11063584 11063584 SP says monomer -- Annotation transfered from 1s1z 1f9a NO 6 6 D3 D3 10986466 10986466 Remarkably, in spite of the fact that the two enzymes share the same fold and hexameric assembly, a striking difference in their quaternary structure is observed - interesting 1f9c NO 8 8 D4 D4 11080642 11080642 Paper says octamer -- Annotation transfered from 2muc 1f9h PROBNOT 1 1 NPS NPS 12578370 12578370 EcoCyc & SP say monomer. -- Annotation transfered from 1eqm 1f9i PROBNOT 1 1 NPS NPS 11063584 11063584 SP says monomer -- Annotation transfered from 1s1z 1f9j PROBNOT 4 4 C2 C2 11173499 11173499 Ubiquitin binds to proteins in different forms that may lead to the degradation of the target protein. For this reason I will consider all the ubiquitin structures to be correct. i.e. different forms may exist. 1f9k NO 2 2 C2 C2 11183779 11183779 Paper says dimeric - PISA seems wrong 1f9m_1 PROBNOT 1 1 NPS NPS 10964566 10964566 Paper says: Whereas thioredoxin f crystallized as a monomer, both truncated thioredoxin f and thioredoxin m crystallized as non-covalent dimers - PISA says monomer - automatic transfer from 1faa 1f9m_2 PROBNOT 1 1 NPS NPS 10964566 10964566 Paper says: Whereas thioredoxin f crystallized as a monomer, both truncated thioredoxin f and thioredoxin m crystallized as non-covalent dimers - PISA says monomer - automatic transfer from 1faa 1f9p PROBYES 1 4 NPS D2 0 0 PISA says tetramer and similar complexes are tetramers 1f9q PROBNOT 4 4 D2 D2 0 0 SP says tetramer -- Annotation transfered from 1rhp 1f9r PROBNOT 4 4 D2 D2 0 0 SP says tetramer -- Annotation transfered from 1rhp 1f9s PROBNOT 4 4 D2 D2 0 0 SP says tetramer -- Annotation transfered from 1rhp 1f9t NO 1 1 NPS NPS 11387196 11387196 Missing dimerization coil-coil -- Annotation transfered from 3kar 1f9u NO 1 1 NPS NPS 11387196 11387196 Missing dimerization coil-coil -- Annotation transfered from 3kar 1f9v NO 1 1 NPS NPS 11387196 11387196 Missing dimerization coil-coil -- Annotation transfered from 3kar 1f9w NA 2 2 C2 C2 11387196 11387196 This structure is apparently compatible with a step during the kinesin walk - interesting 1f9y PROBNOT 1 1 NPS NPS 12578370 12578370 EcoCyc & SP say monomer. -- Annotation transfered from 1eqm 1fa2 NO 4 4 D2 D2 7777485 7777485 Paper says tetramer 1fa9 NO 2 2 C2 C2 10949035 10949035 1faa PROBNOT 1 1 NPS NPS 10964566 10964566 Paper says: Whereas thioredoxin f crystallized as a monomer, both truncated thioredoxin f and thioredoxin m crystallized as non-covalent dimers - PISA says monomer 1fag_1 NA 1 1 NPS NPS 9033595 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1fag_2 NA 1 1 NPS NPS 9033595 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1fag_3 NA 1 1 NPS NPS 9033595 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1fag_4 NA 1 1 NPS NPS 9033595 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1fah_1 NA 1 1 NPS NPS 7578081 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1fah_2 NA 1 1 NPS NPS 7578081 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1faj NO 6 6 D3 D3 15299678 0 SP and EcoCyc say hexamer -- Annotation transfered from 1mjz 1fan NO 1 1 NPS NPS 8518731 8518731 10731422 says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium - pH induced oligomerization -- Annotation transfered from 9pti 1fas NA 1 1 NPS NPS 1429564 1429564 Ask the persons who work with it 1fat NO 4 4 D2 D2 8702788 8702788 SP says tetramer 1fax PROBNOT 2 2 NPS NPS 8939944 8939944 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1fay_1 NO 2 2 C2 C2 11183779 11183779 Paper says dimeric - PISA seems wrong - automatic transfer from 1f9k 1fay_2 NO 2 2 C2 C2 11183779 11183779 Paper says dimeric - PISA seems wrong - automatic transfer from 1f9k 1fay_3 NO 2 2 C2 C2 11183779 11183779 Paper says dimeric - PISA seems wrong - automatic transfer from 1f9k 1fay_4 NO 2 2 C2 C2 11183779 11183779 Paper says dimeric - PISA seems wrong - automatic transfer from 1f9k 1fb2_1 PROBNOT 1 1 NPS NPS 11717491 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 1fb2_2 PROBNOT 1 1 NPS NPS 11717491 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 1fb5 NO 3 3 C3 C3 14527149 14527149 Paper says trimer -- Annotation transfered from 1oth 1fb7 NO 2 2 C2 C2 11106162 11106162 -- Annotation transfered from 1ajx 1fbc NO 4 4 D2 D2 8382525 8382525 -- Annotation transfered from 1eyi 1fbd NO 4 4 D2 D2 8382525 8382525 -- Annotation transfered from 1eyi 1fbe NO 4 4 D2 D2 8382525 8382525 -- Annotation transfered from 1eyi 1fbf NO 4 4 D2 D2 8382525 8382525 -- Annotation transfered from 1eyi 1fbg NO 4 4 D2 D2 8382525 8382525 -- Annotation transfered from 1eyi 1fbh NO 4 4 D2 D2 8382525 8382525 -- Annotation transfered from 1eyi 1fbn PROBYES 1 2 NPS C2 10654930 10654930 Native gel electrophoresis indicated that Mj0697 dimerizes in solution (data not shown), suggesting that the interdomain sheet observed in the crystal may be a functional molecular interface. - PISA dimer seems right 1fbp NO 4 4 D2 D2 2164670 2164670 -- Annotation transfered from 1eyi 1fbq PROBYES 2 1 NS NPS 11305238 11305238 The protein is made of a DNA BD and a trimerization domain. Since the trimerization is not part of the structure I guess it should be a monomer 1fbs PROBYES 2 1 NS NPS 11305238 11305238 The protein is made of a DNA BD and a trimerization domain. Since the trimerization is not part of the structure I guess it should be a monomer -- Annotation transfered from 1fbq 1fbt PROBNOT 2 2 C2 C2 8634242 8634242 Paper says: the bisphosphatase dimerizes at high protein concentrations. We believe that the two subunits found in the crystallographic asymmetric unit may represent the dimeric form of the bisphosphatase domain and perhaps the interface contained in the bifunctional enzyme. 1fbu PROBYES 2 1 NS NPS 11305238 11305238 The protein is made of a DNA BD and a trimerization domain. Since the trimerization is not part of the structure I guess it should be a monomer -- Annotation transfered from 1fbq 1fby YES 2 2 NS C2 10835357 10835357 1fbz_1 PROBNOT 1 1 NPS NPS 10944210 7532720 BU changed since last release and is now corrected - - automaticaly inferred from 1cwe 1fbz_2 PROBNOT 1 1 NPS NPS 10944210 7532720 BU changed since last release and is now corrected - - automaticaly inferred from 1cwe 1fc0 NO 2 2 C2 C2 10949035 10949035 1fc1 NO 2 2 C2 C2 7236608 7236608 1fc3 PROBYES 3 1 NS NPS 11069648 11069648 Paper says: The intermolecular contacts are not extensive; instead, they are typical of lattice interactions in crystals and consistent with measurements in solution, which suggest that C-Spo0A is a monomer. 1fc4 NO 2 2 C2 C2 11318637 11318637 Paper says dimer. There is experimental evidence that KBL and threonine dehydrogenase (TDH, EC 1.1.1.103), the two enzymes catalyzing two consecutive reactions in threonine degradation, form a complex. This has been determined by gel filtration and fluorescence experiments, and the measured stoichiometry indicates that two dimers of KBL are associated with one tetramer of TDH (7). The structure of KBL with the two active sites on the same side of the dimer suggests that KBL binds to TDH with this face opposite the TDH active sites, which would facilitate channeling of the unstable 2-amino-3-ketobutyrate. - interesting for sym-sym interactions 1fc5 NO 2 2 C2 C2 11428898 11428898 Interface geometry conserved with 1uz5 (34%) 1fca PROBNOT 1 1 NPS NPS 15299316 0 No info, PISA says monomer -- Annotation transfered from 1fdn 1fcb NO 4 4 C2 C4 2329585 2329585 The structure is a cyclic tetramer but only C2 is detected because two small domain (out of the four) are unfolded and not visible. 1fcc YES 4 2 C2 NPS 7788293 7788293 BU changed since last release and is now incorrect - 1fcg YES 2 1 C2 NPS 10331870 11397093 We showed that FcgRII is monomeric in solution as proven by size exclusion chromatography of both baculo-derived,23 thus glycosylated, and E. coli material19 and conclude that the previously observed dimer originates from the requirements of crystal packing. 1fcm_1 PROBNOT 1 1 NPS NPS -1 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1fcm_2 PROBNOT 1 1 NPS NPS -1 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1fcn_1 PROBNOT 1 1 NPS NPS -1 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1fcn_2 PROBNOT 1 1 NPS NPS -1 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1fco_1 PROBNOT 1 1 NPS NPS -1 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1fco_2 PROBNOT 1 1 NPS NPS -1 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1fcs NO 1 1 NPS NPS 8462669 8462669 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1fcx PROBNOT 1 1 NPS NPS 10964567 10964567 Do not talk about monomer nor dimer - PISA says monomer, they all crystallize as monomers so I assume they are really monomers. -- Annotation transfered from 1exa 1fcy PROBNOT 1 1 NPS NPS 10964567 10964567 Do not talk about monomer nor dimer - PISA says monomer, they all crystallize as monomers so I assume they are really monomers. -- Annotation transfered from 1exa 1fcz PROBNOT 1 1 NPS NPS 10964567 10964567 Do not talk about monomer nor dimer - PISA says monomer, they all crystallize as monomers so I assume they are really monomers. -- Annotation transfered from 1exa 1fd0 PROBNOT 1 1 NPS NPS 12220491 12220491 Do not talk about monomer nor dimer - PISA says monomer, they all crystallize as monomers so I assume they are really monomers. -- Annotation transfered from 1exa 1fd2 NO 1 1 NPS NPS 2153958 2153958 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1fd9 NO 2 2 C2 C2 11524681 11524681 Similar to 1q6u, fine - still same SCOP error? 1fda NO 1 1 NPS NPS 8245025 8245025 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1fdb NO 1 1 NPS NPS 8245025 8245025 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1fdd NO 1 1 NPS NPS 8245026 8245026 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1fdk PROBYES 2 1 C2 NPS 9369492 9369492 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1bpq 1fdn PROBNOT 1 1 NPS NPS 7966291 7966291 No info, PISA says monomer 1fdp_1 PROBNOT 1 1 NPS NPS 10022823 9757085 - automatic transfer from 1dic 1fdp_2 PROBNOT 1 1 NPS NPS 10022823 9757085 - automatic transfer from 1dic 1fdp_3 PROBNOT 1 1 NPS NPS 10022823 9757085 - automatic transfer from 1dic 1fdp_4 PROBNOT 1 1 NPS NPS 10022823 9757085 - automatic transfer from 1dic 1fdq_1 PROBNOT 1 1 NPS NPS 10854433 10854433 Paper mentions gel filtration and no oligomer, PISa says monomer - automatic transfer from 1fe3 1fdq_2 PROBNOT 1 1 NPS NPS 10854433 10854433 Paper mentions gel filtration and no oligomer, PISa says monomer - automatic transfer from 1fe3 1fds NO 2 2 C2 C2 8805577 8805577 Paper says dimer -- Annotation transfered from 3dhe 1fdt NO 2 2 C2 C2 8805577 8805577 Paper says dimer -- Annotation transfered from 3dhe 1fdu_1 NO 2 2 C2 C2 9525918 10625652 Paper says dimer - automatic transfer from 3dhe 1fdu_2 NO 2 2 C2 C2 9525918 10625652 Paper says dimer - automatic transfer from 3dhe 1fdv_1 NO 2 2 C2 C2 9525918 10625652 Paper says dimer - automatic transfer from 3dhe 1fdv_2 NO 2 2 C2 C2 9525918 10625652 Paper says dimer - automatic transfer from 3dhe 1fdw NO 2 2 C2 C2 9525918 9525918 Paper says dimer -- Annotation transfered from 3dhe 1fdy NO 4 4 D2 D2 9047371 9047371 Interface geometry conserved with 1s5w (25%) 1fdz NO 4 4 D2 D2 9047371 9047371 Interface geometry conserved with 1s5w (25%) -- Annotation transfered from 1fdy 1fe0 PROBNOT 2 2 C2 C2 10966647 10966647 Paper says: In these experiments, it is likely that the CdHah1 dimer (Fig. 2d) is so stable that it prevents docking with the Wilson protein and subsequent metal ion transfer. Which implies a true dimer 1fe2 NO 2 2 C2 C2 11121413 11121413 -- Annotation transfered from 1cqe 1fe3 PROBNOT 1 1 NPS NPS 10854433 10854433 Paper mentions gel filtration and no oligomer, PISa says monomer 1fe4 PROBNOT 2 2 C2 C2 10966647 10966647 Paper says: In these experiments, it is likely that the CdHah1 dimer (Fig. 2d) is so stable that it prevents docking with the Wilson protein and subsequent metal ion transfer. Which implies a true dimer -- Annotation transfered from 1fe0 1fe5 PROBNOT 1 1 NPS NPS 11286555 11286555 Paper says nothing about oligomer - PISA says monomer 1fea_1 NO 2 2 C2 C2 0 8477734 GR are homodimers - automatic transfer from 1typ 1fea_2 NO 2 2 C2 C2 0 8477734 GR are homodimers - automatic transfer from 1typ 1feb NO 2 2 C2 C2 0 0 GR are homodimers -- Annotation transfered from 1typ 1fec NO 2 2 C2 C2 0 0 GR are homodimers -- Annotation transfered from 1typ 1fee PROBNOT 2 2 C2 C2 10966647 10966647 Paper says: In these experiments, it is likely that the CdHah1 dimer (Fig. 2d) is so stable that it prevents docking with the Wilson protein and subsequent metal ion transfer. Which implies a true dimer -- Annotation transfered from 1fe0 1fej NO 2 2 C2 C2 11340661 11340661 -- Annotation transfered from 1ajx 1fel NO 1 1 NPS NPS 7961949 7961949 Circulating in the plasma, the monomeric RBP molecule (21 kDa) is found associated in a macromolecular complex with the tetrameric thyroxine-binding transthyretin (55 kDa). The formation of the RBP–transthyretin complex is believed to prevent filtration through renal glomeruli of the relatively small RBP molecule. -- Annotation transfered from 1kt5 1fem NO 1 1 NPS NPS 7961949 7961949 Circulating in the plasma, the monomeric RBP molecule (21 kDa) is found associated in a macromolecular complex with the tetrameric thyroxine-binding transthyretin (55 kDa). The formation of the RBP–transthyretin complex is believed to prevent filtration through renal glomeruli of the relatively small RBP molecule. -- Annotation transfered from 1kt5 1fen NO 1 1 NPS NPS 7961949 7961949 Circulating in the plasma, the monomeric RBP molecule (21 kDa) is found associated in a macromolecular complex with the tetrameric thyroxine-binding transthyretin (55 kDa). The formation of the RBP–transthyretin complex is believed to prevent filtration through renal glomeruli of the relatively small RBP molecule. -- Annotation transfered from 1kt5 1fer NO 1 1 NPS NPS 15299532 0 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1ff0 NO 2 2 C2 C2 11340661 11340661 -- Annotation transfered from 1ajx 1ff2 NO 1 1 NPS NPS 10961993 10961993 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1ff4 NA 2 2 NS NS 0 0 Ask the persons who work with it 1ff5 NO 2 2 C2 C2 10202138 10202138 Cadherin homodimer -- Annotation transfered from 1edh 1fff NO 2 2 C2 C2 11340661 11340661 -- Annotation transfered from 1ajx 1ffi NO 2 2 C2 C2 11340661 11340661 -- Annotation transfered from 1ajx 1ffl NO 2 2 C2 C2 16615077 16615077 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1ffq PROBNOT 1 1 NPS NPS 12554965 12554965 -- Annotation transfered from 1ehn 1ffr PROBNOT 1 1 NPS NPS 11560481 11560481 -- Annotation transfered from 1ehn 1fg3 NO 2 2 C2 C2 11518529 11518529 1fg4_1 NA 1 2 NPS NS 11347894 0 BU changed since last release and is now incorrect - No paper, send email - automaticaly inferred from 1oc8 1fg4_2 NA 1 2 NPS NS 11347894 0 BU changed since last release and is now incorrect - No paper, send email - automaticaly inferred from 1oc8 1fg5 PROBNOT 1 1 NPS NPS 11179209 11179209 Paper says: So far, dimerization of soluble α3GalT has not been reported; it has been proposed that different glycosyltransferases may form non-covalent oligomers during Golgi sorting/trafficking. It is conceivable that the homologous UDP-binding subdomain shared by Golgi glycosyltransferases of different specificities (see below) might support their non-covalent association, increasing their efficiency in glycan biosynthesis. -- Annotation transfered from 1g8o 1fg6 NO 2 2 C2 C2 11340661 11340661 -- Annotation transfered from 1ajx 1fg7 NO 2 2 C2 C2 11518529 11518529 -- Annotation transfered from 1fg3 1fg8 NO 2 2 C2 C2 11340661 11340661 -- Annotation transfered from 1ajx 1fga PROBNOT 1 1 NPS NPS 7691311 7691311 SP says monomer -- Annotation transfered from 1bas 1fgc NO 2 2 C2 C2 11340661 11340661 -- Annotation transfered from 1ajx 1fgi_1 PROBNOT 1 1 NPS NPS 9139660 9774334 BU changed since last release and is now corrected - Paper does not mention dimer and PISA says monomer - automaticaly inferred from 2fgi 1fgi_2 PROBNOT 1 1 NPS NPS 9139660 9774334 BU changed since last release and is now corrected - Paper does not mention dimer and PISA says monomer - automaticaly inferred from 2fgi 1fgk PROBYES 2 1 C2 NPS 8752212 8752212 Paper does not mention dimer and PISA says monomer -- Annotation transfered from 2fgi 1fgl PROBNOT 1 1 NPS NPS 9016720 9016720 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 1fgu YES 2 1 NS NPS 11157767 11157767 Paper says: Human RPA is a heterotrimer with three subunits of ~70, 32 and 14 kDa, which are referred to as RPA70, RPA32 and RPA14, 1fgx_1 PROBNOT 1 1 NPS NPS 10393171 12927542 Paper says nothing, PISA says monomer - automatic transfer from 1pzt 1fgx_2 PROBNOT 1 1 NPS NPS 10393171 12927542 Paper says nothing, PISA says monomer - automatic transfer from 1pzt 1fh2 NO 4 4 D2 D2 11243784 11243784 transthyretin is tetrameric 1fh7 PROBNOT 1 1 NPS NPS 10995222 10995222 Apparently the family doesnt form dimers but there is no clear evidence. -- Annotation transfered from 1exp 1fh8 PROBNOT 1 1 NPS NPS 10995222 10995222 Apparently the family doesnt form dimers but there is no clear evidence. -- Annotation transfered from 1exp 1fh9 PROBNOT 1 1 NPS NPS 10995222 10995222 Apparently the family doesnt form dimers but there is no clear evidence. -- Annotation transfered from 1exp 1fha NO 24 24 Octa Octa 1992356 1992356 Interface geometry conserved with 1lb3 (53%) -- Annotation transfered from 2fha 1fhd PROBNOT 1 1 NPS NPS 10995222 10995222 Apparently the family doesnt form dimers but there is no clear evidence. -- Annotation transfered from 1exp 1fhe NO 2 2 C2 C2 9367777 9367777 1fhg PROBYES 1 2 NPS C2 1404391 9078244 telokin was present in the form of a dimer. 1fhh PROBNOT 1 1 NPS NPS 11344329 11344329 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1fhm 1fhm PROBNOT 1 1 NPS NPS 11344329 11344329 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes 1fhn NO 4 4 D2 D2 11243784 11243784 transthyretin is tetrameric -- Annotation transfered from 1fh2 1fhu PROBNOT 1 1 NPS NPS 10978150 10978150 Paper says monomer -- Annotation transfered from 1fhv 1fhv PROBNOT 1 1 NPS NPS 10978150 15134446 Paper says monomer 1fi4 YES 2 2 C2 C2 11698677 11698677 The protein forms a dimer but I believe this one is not correct (The one from PISA is more likely to be correct). Paper says: using dynamic light scattering S. cerevisiae MDD behaved as a monodisperse dimer with an apparent molecular mass of 110 kDa (predicted mass for the dimer is 94 kDa) in aqueous solution. S. cerevisiae 1fib PROBNOT 1 1 NPS NPS 9016719 9016719 BU changed since last release and is now corrected - Paper doesnt speak about this dimer - automaticaly inferred from 1fic 1fic PROBYES 2 1 NS NPS 9016719 9016719 Paper doesnt speak about this dimer 1fid PROBNOT 1 1 NPS NPS 9016719 9016719 BU changed since last release and is now corrected - Paper doesnt speak about this dimer - automaticaly inferred from 1fic 1fie NO 2 2 C2 C2 7660355 7660355 Paper says dimer -- but wrong reconstruction, PISa get the good interface but makes a tetramer -- Annotation transfered from 1ggt 1fik PROBNOT 1 1 NPS NPS 0 0 SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio -- Annotation transfered from 1fil 1fil PROBNOT 1 1 NPS NPS 0 0 SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio 1fiv NO 2 2 C2 C2 7664111 7664111 -- Annotation transfered from 3fiv 1fiy YES 1 4 NPS D2 9927652 9927652 Interface geometry conserved with 1jqo (40%) 1fj0 YES 4 1 C2 NPS 11742117 11742117 1fj3 PROBNOT 1 1 NPS NPS 11287678 11287678 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1fj6 NO 4 4 D2 D2 10998248 10998248 -- Annotation transfered from 1eyi 1fj9 NO 4 4 D2 D2 10998248 10998248 -- Annotation transfered from 1eyi 1fjh NO 2 2 C2 C2 11007791 11007791 very interesting, tetramerization blocked. cf. paper -- Annotation transfered from 1fk8 1fjj NO 2 2 C2 C2 11439028 11439028 Swissprot says dimer 1fjo PROBNOT 1 1 NPS NPS 11287678 11287678 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1fjq PROBNOT 1 1 NPS NPS 11287678 11287678 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1fjs PROBNOT 2 2 NPS NPS 11027132 11027132 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1fjt PROBNOT 1 1 NPS NPS 11287678 11287678 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1fju PROBNOT 1 1 NPS NPS 11287678 11287678 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1fjv PROBNOT 1 1 NPS NPS 11287678 11287678 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1fjw PROBNOT 1 1 NPS NPS 11287678 11287678 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1fk0 PROBNOT 1 1 NPS NPS 11327766 11327766 Paper does not mention an oligomer and Wheat orthologue was found monomeric (12525478). -- Annotation transfered from 1fk1 1fk1 PROBNOT 1 1 NPS NPS 11327766 11327766 Paper does not mention an oligomer and Wheat orthologue was found monomeric (12525478). 1fk2 PROBNOT 1 1 NPS NPS 11327766 11327766 Paper does not mention an oligomer and Wheat orthologue was found monomeric (12525478). -- Annotation transfered from 1fk1 1fk3 PROBNOT 1 1 NPS NPS 11327766 11327766 Paper does not mention an oligomer and Wheat orthologue was found monomeric (12525478). -- Annotation transfered from 1fk1 1fk4 PROBNOT 1 1 NPS NPS 11327766 11327766 Paper does not mention an oligomer and Wheat orthologue was found monomeric (12525478). -- Annotation transfered from 1fk1 1fk5 PROBNOT 1 1 NPS NPS 11327766 11327766 Paper does not mention an oligomer and Wheat orthologue was found monomeric (12525478). -- Annotation transfered from 1fk1 1fk6 PROBNOT 1 1 NPS NPS 11327766 11327766 Paper does not mention an oligomer and Wheat orthologue was found monomeric (12525478). -- Annotation transfered from 1fk1 1fk7 PROBNOT 1 1 NPS NPS 11327766 11327766 Paper does not mention an oligomer and Wheat orthologue was found monomeric (12525478). -- Annotation transfered from 1fk1 1fk8 NO 2 2 C2 C2 11007791 11007791 very interesting, tetramerization blocked. cf. paper 1fkb NO 1 1 NPS NPS -1 0 Normally monomeric in solution - But very interesting: one mutation (F36M) transforms it into an inducible dimer. Isnt that so interesting? It thus also shows that it can be very simple to form a heterointerfaces, and that a high proportion of supposedly errors in the BU can reflect a potential high affinity (given that 1/2 mutations are introduced) - very nice example! -- Annotation transfered from 1fkh 1fkd YES 2 1 C2 NPS 7684380 7684380 Normally monomeric in solution - But very interesting: one mutation (F36M) transforms it into an inducible dimer. Isnt that so interesting? It thus also shows that it can be very simple to form a heterointerfaces, and that a high proportion of supposedly errors in the BU can reflect a potential high affinity (given that 1/2 mutations are introduced) - very nice example! -- Annotation transfered from 2fke 1fkf YES 2 1 C2 NPS 1709302 1709302 Normally monomeric in solution - But very interesting: one mutation (F36M) transforms it into an inducible dimer. Isnt that so interesting? It thus also shows that it can be very simple to form a heterointerfaces, and that a high proportion of supposedly errors in the BU can reflect a potential high affinity (given that 1/2 mutations are introduced) - very nice example! -- Annotation transfered from 2fke 1fkg NO 1 1 NPS NPS -1 0 Normally monomeric in solution - But very interesting: one mutation (F36M) transforms it into an inducible dimer. Isnt that so interesting? It thus also shows that it can be very simple to form a heterointerfaces, and that a high proportion of supposedly errors in the BU can reflect a potential high affinity (given that 1/2 mutations are introduced) - very nice example! -- Annotation transfered from 1fkh 1fkh NO 1 1 NPS NPS -1 10852943 Normally monomeric in solution - But very interesting: one mutation (F36M) transforms it into an inducible dimer. Isnt that so interesting? It thus also shows that it can be very simple to form a heterointerfaces, and that a high proportion of supposedly errors in the BU can reflect a potential high affinity (given that 1/2 mutations are introduced) - very nice example! 1fki YES 2 1 NS NPS -1 0 -- Annotation transfered from 1qpl 1fkj YES 2 1 C2 NPS 15299838 0 Normally monomeric in solution - But very interesting: one mutation (F36M) transforms it into an inducible dimer. Isnt that so interesting? It thus also shows that it can be very simple to form a heterointerfaces, and that a high proportion of supposedly errors in the BU can reflect a potential high affinity (given that 1/2 mutations are introduced) - very nice example! -- Annotation transfered from 2fke 1fkk YES 2 1 C2 NPS 15299838 0 Normally monomeric in solution - But very interesting: one mutation (F36M) transforms it into an inducible dimer. Isnt that so interesting? It thus also shows that it can be very simple to form a heterointerfaces, and that a high proportion of supposedly errors in the BU can reflect a potential high affinity (given that 1/2 mutations are introduced) - very nice example! -- Annotation transfered from 2fke 1fkl NO 1 1 NPS NPS 15299838 0 Normally monomeric in solution - But very interesting: one mutation (F36M) transforms it into an inducible dimer. Isnt that so interesting? It thus also shows that it can be very simple to form a heterointerfaces, and that a high proportion of supposedly errors in the BU can reflect a potential high affinity (given that 1/2 mutations are introduced) - very nice example! -- Annotation transfered from 1fkh 1fkq NO 1 1 NPS NPS 11536356 11536356 -- Annotation transfered from 1fkv 1fkv NO 1 1 NPS NPS 11536356 11536356 1fl0 NO 1 1 NPS NPS 11157763 11157763 Monomer mimics the dimer -- very nice interesting example for a letter to the editor. -- Annotation transfered from 1e7z 1fl2 YES 1 2 NPS C2 11243797 11243797 Interface conserved with 1cl0 (33%) 1fla PROBNOT 1 1 NPS NPS 9063874 9063874 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 2fdx 1fld PROBNOT 1 1 NPS NPS 9063874 9063874 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 2fdx 1flh PROBNOT 1 1 NPS NPS 11679720 11679720 None of the associated paper speaks about oligomeric state - PISA says monomer and related proteins are monomeric -- Annotation transfered from 1psn 1flj PROBNOT 1 1 NPS NPS 11024467 11024467 2496681 says monomeric, may form S-S dimers 1flk_1 PROBYES 2 1 C2 NPS 10984535 12005438 BU changed since last release and is now incorrect - interface conserved with 1czy (55%) - automaticaly inferred from 1kzz 1flk_2 PROBYES 2 1 C2 NPS 10984535 12005438 BU changed since last release and is now incorrect - interface conserved with 1czy (55%) - automaticaly inferred from 1kzz 1fll_1 NO 1 1 NPS NPS 10984535 12005438 interface conserved with 1czy (55%) - automatic transfer from 1kzz 1fll_2 NO 1 1 NPS NPS 10984535 12005438 interface conserved with 1czy (55%) - automatic transfer from 1kzz 1fln PROBNOT 1 1 NPS NPS 9063874 9063874 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 2fdx 1flo NO 4 4 C2 C4 11090626 11090626 Paper says the structure is a pseudo C4 tetramer. 1flq NO 1 1 NPS NPS 11112507 11112507 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1flu NO 1 1 NPS NPS 11112507 11112507 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1flv PROBNOT 1 1 NPS NPS 1303762 1303762 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1ftg 1flw NO 1 1 NPS NPS 11112507 11112507 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1fly NO 1 1 NPS NPS 11112507 11112507 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1fm4 PROBNOT 1 1 NPS NPS 12473456 16272319 Abs detected, besides a Bet v 1 monomer of 17 kDa, a dimer of 34 kDa. In dynamic light scattering, Bet v 1 appeared as dimers and even multimers, but a single condition could be defined where it behaved exclusively monomerically - monomer dimer equilibrium - interesting 1fm5 PROBYES 2 2 NS C2 11101293 11101293 The protein, which exists as a disulfide-linked homodimer on the cell surface, crystallizes as a symmetrical dimer -- PISA doesnt find it 1fmc NO 4 4 D2 D2 8672472 8672472 said in paper 1fmg PROBNOT 1 1 NPS NPS 11679713 11679713 -- Annotation transfered from 1qqu 1fmk PROBNOT 1 1 NPS NPS 9024657 9024657 -- Annotation transfered from 2ptk 1fmo NO 1 1 NPS NPS 9109651 9109651 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1fmp PROBNOT 1 1 NPS NPS 1433290 1433290 Blocked ricin undergoes a pH-dependent reversible self-association, being predominantly dimeric at neutral pH and monomeric at acidic pH. -- Annotation transfered from 1apg 1fmu PROBNOT 1 1 NPS NPS 12127998 12127998 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1fq7 1fmx_1 PROBNOT 1 1 NPS NPS 12127998 11061973 Most eukaryotic aspartic proteinases are monomeric - automatic transfer from 1fq7 1fmx_2 PROBNOT 1 1 NPS NPS 12127998 11061973 Most eukaryotic aspartic proteinases are monomeric - automatic transfer from 1fq7 1fn5 NO 1 1 NPS NPS 11112507 11112507 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1fn6 PROBNOT 1 1 NPS NPS 11679713 11679713 -- Annotation transfered from 1qqu 1fn8 PROBNOT 1 1 NPS NPS 11134922 11134922 -- Annotation transfered from 1gdn 1fnb PROBNOT 1 1 NPS NPS 7897656 7897656 1fnc PROBNOT 1 1 NPS NPS 7897656 7897656 -- Annotation transfered from 1fnb 1fnd PROBNOT 1 1 NPS NPS 7897656 7897656 -- Annotation transfered from 1fnb 1fni PROBNOT 1 1 NPS NPS 11679713 11679713 -- Annotation transfered from 1qqu 1fnu PROBNOT 4 4 D2 D2 11045630 11045630 Tetramer might be relevant: Structural and mutational studies of SEB, SEC, SPEA, and TSST1 suggest MHC binding uses the sur face on the front of Domain 1.Since this sur face is blocked in the SPEA tetramer, tetramer–monomer equilibrium will likely modulate superantigenicity. The ability of factors to stabilize the tetramer could be employed to reduce the ability of SPEA to stimulate T-cell proliferation. -- Annotation transfered from 1ha5 1fnv PROBNOT 4 4 D2 D2 11045630 11045630 Tetramer might be relevant: Structural and mutational studies of SEB, SEC, SPEA, and TSST1 suggest MHC binding uses the sur face on the front of Domain 1.Since this sur face is blocked in the SPEA tetramer, tetramer–monomer equilibrium will likely modulate superantigenicity. The ability of factors to stabilize the tetramer could be employed to reduce the ability of SPEA to stimulate T-cell proliferation. -- Annotation transfered from 1ha5 1fnw_1 PROBNOT 4 4 D2 D2 11045630 9878045 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Tetramer might be relevant: Structural and mutational studies of SEB, SEC, SPEA, and TSST1 suggest MHC binding uses the sur face on the front of Domain 1.Since this sur face is blocked in the SPEA tetramer, tetramer–monomer equilibrium will likely modulate superantigenicity. The ability of factors to stabilize the tetramer could be employed to reduce the ability of SPEA to stimulate T-cell proliferation. - automaticaly inferred from 1ha5_3 1fnw_2 PROBNOT 4 4 D2 D2 11045630 9878045 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Tetramer might be relevant: Structural and mutational studies of SEB, SEC, SPEA, and TSST1 suggest MHC binding uses the sur face on the front of Domain 1.Since this sur face is blocked in the SPEA tetramer, tetramer–monomer equilibrium will likely modulate superantigenicity. The ability of factors to stabilize the tetramer could be employed to reduce the ability of SPEA to stimulate T-cell proliferation. - automaticaly inferred from 1ha5_3 1fny NO 4 4 D2 D2 11484224 11484224 1fnz NO 4 4 D2 D2 11484224 11484224 BU changed since last release and is now corrected - bad reconstructuion. subunits far away from each others. 1fo6 NA 4 4 D2 D2 11237598 11237598 Paper says: From biochemical characterization studies of DCase it has been reported that DCase forms a dimer or a trimer. In the crystal structure, DCase exists as an associated homotetramer -- Annotation transfered from 1erz 1foc NO 2 2 C2 C2 11069913 11069913 1fof NO 2 2 C2 C2 11017203 11017203 Paper says dimer - interface geometry conserved with 1k38 (37%) -- Annotation transfered from 1h8z 1foi NO 2 2 C2 C2 11331003 11331003 Clear dimer -- Annotation transfered from 1fol 1foj NO 2 2 C2 C2 11695891 11695891 Clear dimer -- Annotation transfered from 1fol 1fol NO 2 2 C2 C2 11331003 11331003 Clear dimer 1fon PROBYES 2 1 C2 NPS 8168476 8168476 Paper says monomer 1foo NO 2 2 C2 C2 11331003 11331003 Clear dimer -- Annotation transfered from 1fol 1fop NO 2 2 C2 C2 11331003 11331003 Clear dimer -- Annotation transfered from 1fol 1fot PROBNOT 1 1 NPS NPS 11368172 11368172 Paper says nothing about a oligomer - PISA says monomer 1fp1 NO 2 2 C2 C2 11224575 11224575 Interface geometry conserved with 1fp2 (28% id) -- interesting: gene duplication of this homodimer resulting in two paralogous homodimers with < 30% id 1fp2 NO 2 2 C2 C2 11224575 11224575 Interface geometry conserved with 1fp1 (28% id) -- interesting: gene duplication of this homodimer resulting in two paralogous homodimers with < 30% id 1fp5 NO 2 2 C2 C2 11021535 11021535 paper says dimeric 1fpb NO 4 4 D2 D2 1312721 1312721 -- Annotation transfered from 1eyi 1fpd NO 4 4 D2 D2 7703244 7703244 -- Annotation transfered from 1eyi 1fpe NO 4 4 D2 D2 7703244 7703244 -- Annotation transfered from 1eyi 1fpf NO 4 4 D2 D2 7703244 7703244 -- Annotation transfered from 1eyi 1fpg NO 4 4 D2 D2 7703244 7703244 -- Annotation transfered from 1eyi 1fpi NO 4 4 D2 D2 7568043 7568043 -- Annotation transfered from 1eyi 1fpj NO 4 4 D2 D2 7568043 7568043 -- Annotation transfered from 1eyi 1fpk NO 4 4 D2 D2 7568043 7568043 -- Annotation transfered from 1eyi 1fpl NO 4 4 D2 D2 7568043 7568043 -- Annotation transfered from 1eyi 1fpq NO 2 2 C2 C2 11224575 11224575 Interface geometry conserved with 1fp2 (28% id) -- interesting: gene duplication of this homodimer resulting in two paralogous homodimers with < 30% id -- Annotation transfered from 1fp1 1fpr PROBNOT 1 1 NPS NPS 10660565 10660565 Paper says nothing, SP says monomer and PISA too -- Annotation transfered from 1gwz 1fps NO 2 2 C2 C2 8086404 8986756 Interface geometry conserved with 1rtr (27% id) -- Annotation transfered from 1uby 1fpx NO 2 2 C2 C2 11224575 11224575 Interface geometry conserved with 1fp1 (28% id) -- interesting: gene duplication of this homodimer resulting in two paralogous homodimers with < 30% id -- Annotation transfered from 1fp2 1fpy NO 12 12 D6 D6 11329256 11329256 Salmonella typhimurium GS has a molecular mass of 620 kDa and is a dodecamer with 622 symmetry -- Annotation transfered from 1f1h 1fq3 PROBYES 2 1 NS NPS 11209755 10361252 Granzyme B is a 32 kDa monomeric 1fq4 PROBNOT 1 1 NPS NPS 11061973 11061973 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1fq7 1fq5 PROBNOT 1 1 NPS NPS 11061973 11061973 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1fq7 1fq6 PROBNOT 1 1 NPS NPS 11061973 11061973 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1fq7 1fq7 PROBNOT 1 1 NPS NPS 11061973 11061973 Most eukaryotic aspartic proteinases are monomeric 1fq8 PROBNOT 1 1 NPS NPS 11061973 11061973 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1fq7 1fqa PROBNOT 1 1 NPS NPS 11237621 11237621 EcoCyc says monomer -- Annotation transfered from 1nl5 1fqb PROBNOT 1 1 NPS NPS 11237621 11237621 EcoCyc says monomer -- Annotation transfered from 1nl5 1fqc PROBNOT 1 1 NPS NPS 11237621 11237621 EcoCyc says monomer -- Annotation transfered from 1nl5 1fqd PROBNOT 1 1 NPS NPS 11237621 11237621 EcoCyc says monomer -- Annotation transfered from 1nl5 1fqg PROBNOT 1 1 NPS NPS 1436034 1436034 EcoCyc says monomer -- Annotation transfered from 1jwp 1fql PROBNOT 1 1 NPS NPS 11076507 11076507 9000633 says monomeric -- Annotation transfered from 1uga 1fqm PROBNOT 1 1 NPS NPS 11076507 11076507 9000633 says monomeric -- Annotation transfered from 1uga 1fqn PROBNOT 1 1 NPS NPS 11076507 11076507 9000633 says monomeric -- Annotation transfered from 1uga 1fqo NO 6 6 D3 D3 11752775 11752775 SP and EcoCyc say hexamer. -- Annotation transfered from 1cd5 1fqr PROBNOT 1 1 NPS NPS 11076507 11076507 9000633 says monomeric -- Annotation transfered from 1uga 1fqt PROBYES 2 1 NS NPS 11188691 11188691 Paper says: these contacts are highly hydrated, as is typical of crystal contacts that are not expected to occur in solution 1fqw YES 2 1 C2 NPS 11279165 2999789 CheY is a Mr 14,000 monomeric protein 1fqx NO 2 2 C2 C2 11223536 11223536 -- Annotation transfered from 1ajx 1fr3_1 NO 6 6 D3 D3 11080635 11080635 The protein occurs as highly symmetric hexamers binding eight oxyanions. There are two types of oxyanion binding sites in Mo at the interface between two or three peptides. - From the primary citation. See also 1gus. 1fr3_2 NO 6 6 D3 D3 11080635 11080635 The protein occurs as highly symmetric hexamers binding eight oxyanions. There are two types of oxyanion binding sites in Mo at the interface between two or three peptides. - From the primary citation. See also 1gus. - automatic transfer from 1fr3_1 1fr4 PROBNOT 1 1 NPS NPS 11076507 11076507 9000633 says monomeric -- Annotation transfered from 1uga 1fr7_1 PROBNOT 1 1 NPS NPS 11076507 8987974 9000633 says monomeric - automatic transfer from 1uga 1fr7_2 PROBNOT 1 1 NPS NPS 11076507 8987974 9000633 says monomeric - automatic transfer from 1uga 1fr8 PROBYES 2 1 NS NPS 10393171 10393171 Paper says: which suggests that dimeriz- ation is unlikely to occur in solution. - SP says dimer but 130aa are not in the structure 1fr9 PROBNOT 8 8 D4 D4 10978347 10978347 Paper says: Dynamic light scattering data of the purified protein2 at concentrations between 1 and 2 mg/ml indicate an equilibrium between a monomeric and oligomeric form of the enzyme. [...] The oligomeric form observed by dynamic light scattering presumably corresponds to an octamer. - In addition, dimer interface geometry seems conserved (even though very poorly) - monomer octamer equilibrium 1frb PROBNOT 1 1 NPS NPS 7578036 7578036 PISA says monomer and most proteins related to it are monomeric 1frh NO 1 1 NPS NPS 8132582 8132582 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1fri NO 1 1 NPS NPS 8132582 8132582 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1frj NO 1 1 NPS NPS 8132582 8132582 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1frk NO 1 1 NPS NPS 8132582 8132582 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1frl NO 1 1 NPS NPS 8132582 8132582 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1frm NO 1 1 NPS NPS 8132582 8132582 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. 1frn PROBNOT 1 1 NPS NPS 7677850 7677850 -- Annotation transfered from 1fnb 1fro_1 NO 2 2 C2 C2 9218781 10521255 Interface geometry conserved with 1kll (28%) -- interesting: only case I know where two domain swapped proteins diverge and stay swapped. - automatic transfer from 1qin 1fro_2 NO 2 2 C2 C2 9218781 10521255 Interface geometry conserved with 1kll (28%) -- interesting: only case I know where two domain swapped proteins diverge and stay swapped. - automatic transfer from 1qin 1frp NO 4 4 D2 D2 7809062 7809062 -- Annotation transfered from 1eyi 1frq PROBNOT 1 1 NPS NPS 9852055 9852055 -- Annotation transfered from 1fnb 1frw PROBNOT 8 8 D4 D4 10978347 10978347 Paper says: Dynamic light scattering data of the purified protein2 at concentrations between 1 and 2 mg/ml indicate an equilibrium between a monomeric and oligomeric form of the enzyme. [...] The oligomeric form observed by dynamic light scattering presumably corresponds to an octamer. - In addition, dimer interface geometry seems conserved (even though very poorly) - monomer octamer equilibrium -- Annotation transfered from 1fr9 1frx NO 1 1 NPS NPS 7479727 7479727 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1frz NO 6 6 D3 D3 11752775 11752775 SP and EcoCyc say hexamer. -- Annotation transfered from 1cd5 1fs3 NO 1 1 NPS NPS 11742124 11742124 -- Annotation transfered from 6rsa 1fs4 NO 2 2 C2 C2 16222658 0 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1fs5 NO 6 6 D3 D3 11752775 11752775 SP and EcoCyc say hexamer. -- Annotation transfered from 1cd5 1fs6 NO 6 6 D3 D3 11752775 11752775 SP and EcoCyc say hexamer. -- Annotation transfered from 1cd5 1fsa NO 4 4 D2 D2 8931152 8931152 -- Annotation transfered from 1eyi 1fsf NO 6 6 D3 D3 11752775 11752775 SP and EcoCyc say hexamer. -- Annotation transfered from 1cd5 1fsg NO 4 4 D2 D2 11188695 11188695 Teramer, interface conserved down to 40% (1hmp) -- Annotation transfered from 1qk3 1fsn_1 PROBNOT 1 1 NPS NPS 11076507 8987974 9000633 says monomeric - automatic transfer from 1uga 1fsn_2 PROBNOT 1 1 NPS NPS 11076507 8987974 9000633 says monomeric - automatic transfer from 1uga 1fsq_1 PROBNOT 1 1 NPS NPS 11076507 8987974 9000633 says monomeric - automatic transfer from 1uga 1fsq_2 PROBNOT 1 1 NPS NPS 11076507 8987974 9000633 says monomeric - automatic transfer from 1uga 1fsr_1 PROBNOT 1 1 NPS NPS 11076507 8987974 9000633 says monomeric - automatic transfer from 1uga 1fsr_2 PROBNOT 1 1 NPS NPS 11076507 8987974 9000633 says monomeric - automatic transfer from 1uga 1fsu PROBNOT 1 1 NPS NPS 9032078 9032078 1fsw PROBYES 2 1 C2 NPS 11182316 11182316 AmpC is a class C beta Lactamase and those are monomeric (12951239) -- Annotation transfered from 1c3b 1fsy PROBYES 2 1 C2 NPS 11182316 11182316 AmpC is a class C beta Lactamase and those are monomeric (12951239) -- Annotation transfered from 1c3b 1ft5 PROBNOT 1 1 NPS NPS 11372197 11372197 Paper says nothing, PISA says monomer and family mostly monomeric -- Annotation transfered from 1bvb 1ft6 PROBNOT 1 1 NPS NPS 11372197 11372197 Paper says nothing, PISA says monomer and family mostly monomeric -- Annotation transfered from 1bvb 1ft7 NO 1 1 NPS NPS 11401547 0 Aminopeptidase from Aeromonas proteolytica (AAP) is a small, monomeric enzyme (32KDa) -- Annotation transfered from 1cp6 1fta NO 4 4 D2 D2 7961695 7961695 1ftc_1 NO 1 1 NPS NPS 9188450 8132582 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. - automatic transfer from 1frm 1ftc_2 NO 1 1 NPS NPS 9188450 8132582 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. - automatic transfer from 1frm 1ftg PROBNOT 1 1 NPS NPS 8599758 8599758 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins 1ftj_1 YES 1 2 NPS C2 11086992 12015593 Paper says dimer (and shows it) - automatic transfer from 1lbb 1ftj_2 YES 1 2 NPS C2 11086992 12015593 Paper says dimer (and shows it) - automatic transfer from 1lbb 1ftj_3 YES 1 2 NPS C2 11086992 12015593 Paper says dimer (and shows it) - automatic transfer from 1lbb 1ftk PROBYES 1 2 NPS C2 11086992 11086992 Paper says dimer and they show it 1ftl NO 2 2 C2 C2 11086992 11086992 Paper says this dimer is real -- Annotation transfered from 1mqi 1ftm_1 YES 1 2 NPS C2 11086992 12015593 Paper says dimer (and shows it) - automatic transfer from 1lbb 1ftm_2 YES 1 2 NPS C2 11086992 12015593 Paper says dimer (and shows it) - automatic transfer from 1lbb 1ftm_3 YES 1 2 NPS C2 11086992 12015593 Paper says dimer (and shows it) - automatic transfer from 1lbb 1ftn PROBNOT 1 1 NPS NPS 9302995 9302995 -- Annotation transfered from 1a2b 1fto_1 YES 1 2 NPS C2 11086992 12015593 Paper says dimer (and shows it) - automatic transfer from 1lbb 1fto_2 YES 1 2 NPS C2 11086992 12015593 Paper says dimer (and shows it) - automatic transfer from 1lbb 1ftp PROBYES 2 1 NS NPS 7918460 7918460 PISA, SP and I think it should be monomeric 1ftq NO 2 2 C2 C2 16222658 0 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1ftw NO 2 2 C2 C2 16222658 0 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1fty NO 2 2 C2 C2 16222658 0 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1fu0_1 NO 1 1 NPS NPS 11054290 8126724 SP says monomer - automatic transfer from 1ptf 1fu0_2 NO 1 1 NPS NPS 11054290 8126724 SP says monomer - automatic transfer from 1ptf 1fu1 PROBYES 4 2 NS C2 11080143 11080143 1fu4 NO 2 2 C2 C2 16222658 0 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1fu7 NO 2 2 C2 C2 16222658 0 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1fu8 NO 2 2 C2 C2 16222658 0 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1fua NO 4 4 C4 C4 15299567 0 -- Annotation transfered from 1e4a 1fue PROBNOT 1 1 NPS NPS 11790835 11790835 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins 1fug NO 4 4 D2 D2 8723769 8723769 -- Annotation transfered from 1rg9 1fuj PROBYES 4 1 D2 NPS 8757293 8757293 they speak about the tetramer but not about its biological relevance. Inspection of the structure let me guess that it is probably not biologicaly relevant. Also the arrangment is different from experientaty verified tetramers with same dom. arch. 1fun_1 PROBNOT 2 2 C2 C2 9294870 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1fun_2 PROBNOT 2 2 C2 C2 9294870 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1fun_3 PROBNOT 2 2 C2 C2 9294870 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1fun_4 PROBNOT 2 2 C2 C2 9294870 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1fun_5 PROBNOT 2 2 C2 C2 9294870 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1fuo NO 4 4 D2 D2 8909293 8909293 Interface geometry conserved with 1q5n (22%) -- Annotation transfered from 1fur 1fup NO 4 4 D2 D2 8909293 8909293 Interface geometry conserved with 1q5n (22%) -- Annotation transfered from 1fur 1fuq NO 4 4 D2 D2 8909293 8909293 Interface geometry conserved with 1q5n (22%) -- Annotation transfered from 1fur 1fur NO 4 4 D2 D2 9098893 9098893 Interface geometry conserved with 1q5n (22%) 1fuu PROBNOT 2 2 NPS NPS 11087862 10606264 Paper says: Superdex-75 column (Pharmacia)+ eIF4A eluted at the volume expected for a monomeric protein+ 1fux NO 2 2 C2 C2 11439028 11439028 SwissProt says dimer 1fuy NO 4 4 C2 C2 11034989 11034989 Paper says a2b2 -- Annotation transfered from 2wsy 1fv0_1 PROBNOT 1 1 NPS NPS 12206661 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 1fv0_2 PROBNOT 1 1 NPS NPS 12206661 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 1fv9 PROBNOT 1 1 NPS NPS 11052791 11052791 -- Annotation transfered from 1owd 1fvj_1 NA 1 1 NPS NPS 9300489 10700276 BU changed since last release and is now corrected - It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant - automaticaly inferred from 1ac1 1fvj_2 NA 1 1 NPS NPS 9300489 10700276 BU changed since last release and is now corrected - It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant - automaticaly inferred from 1ac1 1fvk NA 2 1 C2 NPS 9300489 10700276 It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant 1fvo_1 NO 3 3 C3 C3 11237854 9852088 Paper says trimer - automatic transfer from 1oth 1fvo_2 NO 3 3 C3 C3 11237854 9852088 Paper says trimer - automatic transfer from 1oth 1fvt NO 1 1 NPS NPS 11141566 11141566 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1fvx PROBNOT 1 1 NPS NPS 9063874 9063874 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 2fdx 1fw0 YES 1 2 NPS C2 11086992 11086992 Paper says dimer 1fw1 NO 2 2 C2 C2 11327815 11327815 1fw4 PROBNOT 1 1 NPS NPS 11320306 11320306 -- Annotation transfered from 3cln 1fwa NO 9 9 C3 C3 9201965 9201965 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1fwb NO 9 9 C3 C3 9201965 9201965 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1fwc NO 9 9 C3 C3 9201965 9201965 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1fwd NO 9 9 C3 C3 9201965 9201965 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1fwe NO 9 9 C3 C3 9201965 9201965 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1fwf NO 9 9 C3 C3 9201965 9201965 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1fwg NO 9 9 C3 C3 9201965 9201965 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1fwh NO 9 9 C3 C3 9201965 9201965 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1fwi NO 9 9 C3 C3 8702515 8702515 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1fwj NO 9 9 C3 C3 9201965 9201965 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1fwm NO 2 2 C2 C2 16615077 16615077 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1fwn NO 4 4 D2 D2 11115499 11115499 Paper says tetramer -- Annotation transfered from 1fws 1fws NO 4 4 D2 D2 11115499 11115499 Paper says tetramer 1fwt NO 4 4 D2 D2 11115499 11115499 Paper says tetramer -- Annotation transfered from 1fws 1fww NO 4 4 D2 D2 11115499 11115499 Paper says tetramer -- Annotation transfered from 1fws 1fwz PROBNOT 2 2 C2 C2 11320302 11320302 1fx1 PROBNOT 1 1 NPS NPS -1 0 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1f4p 1fx2 YES 2 1 NS NPS 11157750 11157750 Paper says monomer 1fx4 YES 2 1 NS NPS 11157750 11157750 Paper says monomer 1fx5 NO 2 2 C2 C2 11090284 11090284 paper says dimer 1fx6 NO 4 4 D2 D2 11115499 11115499 Paper says tetramer -- Annotation transfered from 1fws 1fx8 NO 4 4 C4 C4 11039922 11039922 Paper says tetramer -- Annotation transfered from 1ldi 1fx9 PROBNOT 2 2 C2 C2 11170377 11170377 Papers of identical structures speak about the dimer as something relevant but it is interesting to note that two modes of dimerization exist among these proteins. I have not seen this discussed 1fxa_1 PROBNOT 1 1 NPS NPS 1902376 9287153 Paper does not mention oligomer - similar proteins are monomeric - automatic transfer from 1j7c 1fxa_2 PROBNOT 1 1 NPS NPS 1902376 9287153 Paper does not mention oligomer - similar proteins are monomeric - automatic transfer from 1j7c 1fxd PROBNOT 2 2 C2 C2 2056535 2056535 SP says homodimer - 8132528 also says so. 1fxf PROBNOT 2 2 C2 C2 11170377 11170377 Papers of identical structures speak about the dimer as something relevant but it is interesting to note that two modes of dimerization exist among these proteins. I have not seen this discussed -- Annotation transfered from 1fx9 1fxo_1 NO 4 4 D2 D2 11118200 11118200 Interface geometry conserved with 1lvw (61%) - automatic transfer from 1g3l 1fxo_2 NO 4 4 D2 D2 11118200 11118200 Interface geometry conserved with 1lvw (61%) - automatic transfer from 1g3l 1fxp NO 4 4 D2 D2 11115499 11115499 Paper says tetramer -- Annotation transfered from 1fws 1fxq NO 4 4 D2 D2 11115499 11115499 Paper says tetramer -- Annotation transfered from 1fws 1fxr PROBNOT 2 2 C2 C2 7803404 7803404 SP says dimer, PISA too 1fxs YES 2 2 NS C2 9862812 9862812 1fxu YES 1 3 NPS C3 11134924 11134924 Paper says trimer -- Annotation transfered from 1b8n 1fxy PROBYES 2 1 C2 NPS 9707558 9707558 Trypsin is monomeric 1fxz NO 3 3 C3 C3 11124907 11124907 Paper says: In the cell, the constituent subunits are synthesized as a single polypeptide precursor, preproglycinin. The signal sequence is removed co-translationally in the endoplasmic reticulum (ER) and the resultant proglycinin assembles into trimers of about 8 S in size. As the proglycinin is sorted to protein storage vacuoles (PSV), a specific post-translational cleavage occurs between asparagine and glycine, resulting in a mature subunit consisting of the acidic and basic polypeptides. Finally, glycinin assembles into a hexamer of about 11 S. It has been demonstrated that the cleavage is a trigger for the formation of hexamers. - So the trimer exists and is an intermediate specie. -- very interesting case 1fy1 NO 1 1 NPS NPS 11170199 11170199 PISA and SP say monomer -- Annotation transfered from 1a7s 1fy3 NO 1 1 NPS NPS 11170199 11170199 PISA and SP say monomer -- Annotation transfered from 1a7s 1fy4 PROBNOT 1 1 NPS NPS 11134922 11134922 -- Annotation transfered from 1gdn 1fy5 PROBNOT 1 1 NPS NPS 11134922 11134922 -- Annotation transfered from 1gdn 1fy6 NO 4 4 D2 D2 11115499 11115499 Paper says tetramer -- Annotation transfered from 1fws 1fyk PROBNOT 1 1 NPS NPS 11599025 11599025 The protein is made of a DNA BD and a trimerization domain. Since the trimerization is not part of the structure I guess it should be a monomer 1fyl_1 PROBYES 2 1 C2 NPS 11599025 11599025 BU changed since last release and is now incorrect - The protein is made of a DNA BD and a trimerization domain. Since the trimerization is not part of the structure I guess it should be a monomer - automaticaly inferred from 1fyk 1fyl_2 PROBYES 2 1 C2 NPS 11599025 11599025 BU changed since last release and is now incorrect - The protein is made of a DNA BD and a trimerization domain. Since the trimerization is not part of the structure I guess it should be a monomer - automaticaly inferred from 1fyk 1fym_1 PROBYES 2 1 C2 NPS 11599025 11305238 BU changed since last release and is now incorrect - The protein is made of a DNA BD and a trimerization domain. Since the trimerization is not part of the structure I guess it should be a monomer - automaticaly inferred from 1fbq 1fym_2 PROBYES 2 1 C2 NPS 11599025 11305238 BU changed since last release and is now incorrect - The protein is made of a DNA BD and a trimerization domain. Since the trimerization is not part of the structure I guess it should be a monomer - automaticaly inferred from 1fbq 1fyn PROBNOT 1 1 NPS NPS 7664083 7664083 7687536 says: The flow rate was 1 ml/min. SH3 eluted in two peaks, centred at 85 and 105 ml, indicating a possible dimer-monomer equilibrium. 1fyu NO 2 2 C2 C2 11274466 11274466 -- Annotation transfered from 1ax0 1fzd_1 PROBYES 4 1 NS NPS 9689040 9689040 all vertebrate fibrinogens are now dimers of heterotrimers -- interesting story about fibrinogen evolution --> would be nice if I could sort things out! 1fzd_2 PROBYES 4 1 NS NPS 9689040 9689040 all vertebrate fibrinogens are now dimers of heterotrimers -- interesting story about fibrinogen evolution --> would be nice if I could sort things out! - automatic transfer from 1fzd_1 1fzw_1 NO 4 4 D2 D2 11118200 11118200 Interface geometry conserved with 1lvw (61%) - automatic transfer from 1g3l 1fzw_2 NO 4 4 D2 D2 11118200 11118200 Interface geometry conserved with 1lvw (61%) - automatic transfer from 1g3l 1fzy_1 PROBNOT 1 1 NPS NPS 11591345 11591345 No information is given and PISA says monomer, which seems consistent across the family. 1fzy_2 PROBNOT 1 1 NPS NPS 11591345 11591345 No information is given and PISA says monomer, which seems consistent across the family. -- Annotation transfered from 1fzy_1 1fzz PROBNOT 1 1 NPS NPS 11310599 11310599 -- Annotation transfered from 1c1m 1g05_1 PROBNOT 1 1 NPS NPS 11327577 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1g05_2 PROBNOT 1 1 NPS NPS 11327577 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1g06 NO 1 1 NPS NPS 11316887 11316887 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1g07 NO 1 1 NPS NPS 11316887 11316887 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1g0d PROBNOT 1 1 NPS NPS 11080504 11080504 Paper says: FTG has some advantages for studying the structure-function relationship because FTG works as a monomer, whereas human factor XIII works as a homodimer 1g0e PROBNOT 1 1 NPS NPS 11327835 11327835 9000633 says monomeric -- Annotation transfered from 1uga 1g0f PROBNOT 1 1 NPS NPS 11327835 11327835 9000633 says monomeric -- Annotation transfered from 1uga 1g0g NO 1 1 NPS NPS 11316887 11316887 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1g0h NO 2 2 C2 C2 11170378 11170378 -- Annotation transfered from 1dk4 1g0i NO 2 2 C2 C2 11170378 11170378 -- Annotation transfered from 1dk4 1g0j NO 1 1 NPS NPS 11316887 11316887 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1g0k NO 1 1 NPS NPS 11316887 11316887 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1g0l NO 1 1 NPS NPS 11316887 11316887 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1g0m NO 1 1 NPS NPS 11316887 11316887 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1g0n NO 4 4 D2 D2 11342131 11342131 Said in paper that it is a tetramer -- Annotation transfered from 1g0o 1g0o NO 4 4 D2 D2 11342131 11342131 Said in paper that it is a tetramer 1g0p NO 1 1 NPS NPS 11316887 11316887 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1g0q NO 1 1 NPS NPS 11316887 11316887 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1g0r_1 NO 4 4 D2 D2 11118200 11118200 Interface geometry conserved with 1lvw (61%) - automatic transfer from 1g3l 1g0r_2 NO 4 4 D2 D2 11118200 11118200 Interface geometry conserved with 1lvw (61%) - automatic transfer from 1g3l 1g0w YES 1 2 NPS C2 11173463 11173463 Paper says dimer -- the dimer is the same as the one found in a related octamer 1g0y PROBNOT 1 1 NPS NPS 10903327 10903327 Normally forms a 1:1 hetero complex with interleukin so monomer is true. 1g0z NO 2 2 C2 C2 0 0 Paper says dimer - carbohydrate induced homodimer - interesting -- Annotation transfered from 1u4j 1g12 PROBNOT 1 1 NPS NPS 11223512 11223512 -- Annotation transfered from 1ge5 1g15 PROBNOT 1 1 NPS NPS 11083878 11083878 SP says monomer -- Annotation transfered from 1f21 1g16 PROBYES 4 1 NS NPS 11099382 11099382 1g17 PROBYES 2 1 NS NPS 11099382 11099382 1g1a_1 NO 2 2 C2 C2 11243820 11796113 Paper says dimer - automatic transfer from 1keu 1g1a_2 NO 2 2 C2 C2 11243820 11796113 Paper says dimer - automatic transfer from 1keu 1g1c YES 2 2 NS NA 11525170 11525170 BU changed since last release and is now incorrect - Both proteins do not touch each others 1g1d PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1g1f PROBNOT 1 1 NPS NPS 11163213 11163213 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1g1g PROBNOT 1 1 NPS NPS 11163213 11163213 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1g1h PROBNOT 1 1 NPS NPS 11163213 11163213 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1g1l_1 NO 4 4 D2 D2 11118200 11118200 Interface geometry conserved with 1lvw (61%) - automatic transfer from 1g3l 1g1l_2 NO 4 4 D2 D2 11118200 11118200 Interface geometry conserved with 1lvw (61%) - automatic transfer from 1g3l 1g1o NO 4 4 D2 D2 11106758 11106758 1g1q NA 4 4 NS NS 11081633 11081633 1g1r NA 4 4 NS NS 11081633 11081633 1g1s NA 2 2 NS NS 11081633 11081633 1g1u NO 4 4 D2 D2 10970886 10970886 interesting - in the absence of ligand, RXR can exist as an inactive tetramer and that its dissociation, induced by ligand, is important for receptor activation -- Annotation transfered from 1g5y 1g1v NO 1 1 NPS NPS 11316887 11316887 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1g1w NO 1 1 NPS NPS 11316887 11316887 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1g23_1 NO 4 4 D2 D2 11118200 11118200 Interface geometry conserved with 1lvw (61%) - automatic transfer from 1g3l 1g23_2 NO 4 4 D2 D2 11118200 11118200 Interface geometry conserved with 1lvw (61%) - automatic transfer from 1g3l 1g24_1 PROBNOT 1 1 NPS NPS 11114250 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer - automatic transfer from 1gze_2 1g24_2 PROBNOT 1 1 NPS NPS 11114250 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer - automatic transfer from 1gze_2 1g24_3 PROBNOT 1 1 NPS NPS 11114250 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer - automatic transfer from 1gze_2 1g24_4 PROBNOT 1 1 NPS NPS 11114250 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer - automatic transfer from 1gze_2 1g27_1 NO 1 1 NPS NPS 11158755 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1g27_2 NO 1 1 NPS NPS 11158755 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1g27_3 NO 1 1 NPS NPS 11158755 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1g2a_1 NO 1 1 NPS NPS 11158755 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1g2a_2 NO 1 1 NPS NPS 11158755 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1g2a_3 NO 1 1 NPS NPS 11158755 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1g2b PROBNOT 1 1 NPS NPS 11173498 11173498 -- Annotation transfered from 1neg 1g2i NO 6 6 D3 D3 11114201 11114201 Active site at the interface of a dimer. 1g2k NO 2 2 C2 C2 11170625 11170625 -- Annotation transfered from 1ajx 1g2l PROBNOT 2 2 NPS NPS 11342132 11342132 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1g2m PROBNOT 2 2 NPS NPS 11342132 11342132 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1g2n NO 1 1 NPS NPS 11053444 11053444 Paper says: A homogeneous monomeric species was observed in solution. 1g2o NO 3 3 C3 C3 11444966 11444966 Paper says trimer -- interesting SUPERFAMILY for an evolution study 1g2v_1 NO 4 4 D2 D2 11118200 11118200 Interface geometry conserved with 1lvw (61%) - automatic transfer from 1g3l 1g2v_2 NO 4 4 D2 D2 11118200 11118200 Interface geometry conserved with 1lvw (61%) - automatic transfer from 1g3l 1g2w NO 2 2 C2 C2 -1 0 Homodimer -- Annotation transfered from 2daa 1g2x NO 3 3 C3 C3 16508078 16508078 Paper says trimeric in solution 1g31 PROBYES 7 14 C7 C7 9244309 9244309 Paper says: crystal structure of Gp31 shows that its tertiary and quaternary structures are similar to those of GroES - GroES is a 14-mer 1g33 PROBNOT 1 1 NPS NPS 11562941 11562941 Similar structures are either monomers or weak dimers - Paper does not mention dimer -- PISA gives a very strange dimer --> email eugene 1g35 NO 2 2 C2 C2 11170625 11170625 -- Annotation transfered from 1ajx 1g36 PROBNOT 1 1 NPS NPS 11342132 11342132 -- Annotation transfered from 1az8 1g37 PROBNOT 1 1 NPS NPS 11212093 11212093 -- Annotation transfered from 1doj 1g3b PROBNOT 1 1 NPS NPS 11152605 11152605 -- Annotation transfered from 1az8 1g3c PROBNOT 1 1 NPS NPS 11152605 11152605 -- Annotation transfered from 1az8 1g3d PROBNOT 1 1 NPS NPS 11152605 11152605 -- Annotation transfered from 1az8 1g3e PROBNOT 1 1 NPS NPS 11152605 11152605 -- Annotation transfered from 1az8 1g3i NO 24 24 D6 D6 11106733 11106733 -- Annotation transfered from 1kyi 1g3k NO 12 12 D6 D6 11106733 11106733 1g3l NO 4 4 D2 D2 11118200 11118200 Interface geometry conserved with 1lvw (61%) 1g3m NO 2 2 C2 C2 12782487 12782487 Paper says: These loops form the identical interaction as seen in human hydroxysteroid sulfotransferase and human aryl sulfotransferase 3 crystals that has been implicated to be the physiological dimerization interface. Apparently, the V269E mutation did not prevent the hEST from forming the proper dimer in the crystal lattice. - this interface does contain residue 269 so it is probably the good one -- Annotation transfered from 1hy3 1g3o NO 1 1 NPS NPS 11704670 11704670 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1g3p NO 1 1 NPS NPS 9461080 10329170 However, we could find no evidence of dimer formation of D1D2-fd, as judged by gel-filtration chromatography or light-scattering at protein concentrations (10 mg/ml) close to those used in the crystallisation set-up. Dimer formation may therefore be an artifact of the high-salt crystallisation conditions and may not reflect an interaction of biological relevance. -- good interesting example of corrected error for the paper 1g3s PROBNOT 2 2 C2 C2 11320302 11320302 -- Annotation transfered from 1fwz 1g3u NO 2 2 C2 C2 11469859 11469859 Homodimer -- Annotation transfered from 1mrn 1g3w PROBNOT 2 2 C2 C2 11320302 11320302 -- Annotation transfered from 1fwz 1g3y PROBNOT 2 2 C2 C2 11320302 11320302 -- Annotation transfered from 1fwz 1g3z PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1g41 PROBNOT 6 6 C6 C6 11468391 11468391 HSLU is the outer ring so it forms a hexamer (not a dodecamer) 1g42 NO 1 1 NPS NPS 11939779 11939779 SP says monomer 1g43 PROBNOT 1 1 NPS NPS 11092922 11092922 Paper implies monomer -- PISA seems wrong 1g45 PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1g46 PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1g48 PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1g49_1 PROBNOT 1 1 NPS NPS 11150165 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1g49_2 PROBNOT 1 1 NPS NPS 11150165 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1g4a NO 18 18 C6 C6 11250202 11250202 1g4c_1 PROBNOT 1 1 NPS NPS 12578370 11546767 EcoCyc & SP say monomer. - automatic transfer from 1eqm 1g4c_2 PROBNOT 1 1 NPS NPS 12578370 11546767 EcoCyc & SP say monomer. - automatic transfer from 1eqm 1g4h NO 1 1 NPS NPS 11939779 11939779 SP says monomer -- Annotation transfered from 1g42 1g4i PROBNOT 1 1 NPS NPS 11264580 11264580 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1o2e 1g4j PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1g4k_1 PROBNOT 1 1 NPS NPS 11316871 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1g4k_2 PROBNOT 1 1 NPS NPS 11316871 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1g4k_3 PROBNOT 1 1 NPS NPS 11316871 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1g4o PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1g4v NO 2 2 C2 C2 11148029 11148029 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1g4x NO 2 2 C2 C2 11148029 11148029 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1g50_1 NO 2 2 C2 C2 11437591 9338790 paper says dimer - automatic transfer from 1err 1g50_2 NO 2 2 C2 C2 11437591 9338790 paper says dimer - automatic transfer from 1err 1g51 NO 2 2 C2 C2 7966328 7966328 Interface geometry conserved with 1c0a (48%) 1g52 PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1g53 PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1g54 PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1g5a NO 1 1 NPS NPS 11306569 11306569 9882648 says: Under both native and denaturing conditions, the molecular mass obtained was 70 ± 2 kDa (Fig. 3B). This result demonstrates the monomeric structure of the amylosucrase from N. polysaccharea -- Annotation transfered from 1mw1 1g5c_1 PROBNOT 2 2 NS NS 11096105 11096105 Paper says dimer - error with symmetry search? 1g5c_2 PROBNOT 2 2 NS NS 11096105 11096105 Paper says dimer - error with symmetry search? - automatic transfer from 1g5c_1 1g5c_3 PROBNOT 2 2 NS NS 11096105 11096105 Paper says dimer - error with symmetry search? - automatic transfer from 1g5c_1 1g5f NO 1 1 NPS NPS 11939779 11939779 SP says monomer -- Annotation transfered from 1g42 1g5n PROBNOT 1 1 NPS NPS 11342135 11342135 SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1n42 1g5q NO 12 12 Tetr Tetr 11101502 11101502 Interface geometry conserved with 1p3y (30%) -- Annotation transfered from 1g63 1g5s NO 1 1 NPS NPS 11170642 11170642 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1g5y NO 4 4 D2 D2 10970886 10970886 interesting - in the absence of ligand, RXR can exist as an inactive tetramer and that its dissociation, induced by ligand, is important for receptor activation 1g60 PROBNOT 2 2 C2 C2 12954781 12954781 SP says homodimer, paper too 1g63 NO 12 12 Tetr Tetr 11101502 11101502 Interface geometry conserved with 1p3y (30%) 1g68 NA 1 1 NPS NPS 11148033 11148033 Paper says nothing, PISA finds a strong dimer 1g6a NA 1 1 NPS NPS 11148033 11148033 Paper says nothing, PISA finds a strong dimer -- Annotation transfered from 1g68 1g6b NO 1 1 NPS NPS 11704670 11704670 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1g6h NO 1 1 NPS NPS 11470432 11470432 Paper says: soluble MJ1267 is monomeric in the absence of nucleotides at protein concentrations up to 0.34 mM -- Annotation transfered from 1gaj 1g6o NO 6 6 C6 C6 11163218 11163218 PAper says hexamer -- Annotation transfered from 1nlz 1g6q YES 6 2 C2 C2 11101900 11101900 Interface geometry conserved with 1or8 (50% id) -- all the family was a mistaken. Interesting story to tell to show that my job is important!!! 1g6s PROBNOT 1 1 NPS NPS 11171958 11171958 SP says monomer -- Annotation transfered from 1q36 1g6t PROBNOT 1 1 NPS NPS 11171958 11171958 SP says monomer -- Annotation transfered from 1q36 1g6w_1 NO 2 2 C2 C2 11342133 11171973 Interface geometry conserved with 1e6b (26%) - automatic transfer from 1hqo 1g6w_2 NO 2 2 C2 C2 11342133 11171973 Interface geometry conserved with 1e6b (26%) - automatic transfer from 1hqo 1g6x NO 1 1 NPS NPS 11320305 11320305 10731422 says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium - pH induced oligomerization -- Annotation transfered from 1k6u 1g6y NO 2 2 C2 C2 11342133 11342133 Interface geometry conserved with 1e6b (26%) -- Annotation transfered from 1hqo 1g74 NO 1 1 NPS NPS 14594993 14594993 ALBP is monomeric at low and high salt concentrations. -- Annotation transfered from 1alb 1g7f PROBNOT 1 1 NPS NPS 11341829 11341829 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1g7g PROBNOT 1 1 NPS NPS 11341829 11341829 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1g7k NO 4 4 D2 D2 11209050 11209050 Paper says tetramer -- Annotation transfered from 1ggx 1g7n NO 1 1 NPS NPS 14594993 14594993 ALBP is monomeric at low and high salt concentrations. -- Annotation transfered from 1alb 1g7u PROBYES 1 4 NPS D2 11371194 11371194 1g7v YES 1 4 NPS D2 11371194 11371194 paper says homotetramer 1g7w NO 2 2 C2 C2 11148029 11148029 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1g7x NO 2 2 C2 C2 11148029 11148029 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1g82_1 NO 2 2 C2 C2 11223514 11060292 Unlike most FGFs, FGF9 forms dimers in solution with a K(d) of 680 nm. - Monomer dimer equilibrium -- good paper to see techniques to characterize oligom. state. - automatic transfer from 1ihk 1g82_2 NO 2 2 C2 C2 11223514 11060292 Unlike most FGFs, FGF9 forms dimers in solution with a K(d) of 680 nm. - Monomer dimer equilibrium -- good paper to see techniques to characterize oligom. state. - automatic transfer from 1ihk 1g85 NO 2 2 C2 C2 11114310 11114310 Domain Swapped dimer -- Annotation transfered from 1gt1 1g86 NO 1 1 NPS NPS 11834744 11834744 Forms crystals in vivo! 1g88 NO 3 3 C3 C3 11224571 11224571 Interface geometry conserved with 1khx (42%) -- Annotation transfered from 1dd1 1g8a PROBNOT 1 1 NPS NPS 0 0 In contrast, the N-terminal domains are divergent which may explain why some forms of fibrillarin apparently homodimerize (M. jannashii) while others are monomeric (P. furiosus and A. fulgidus). -- Annotation transfered from 1pry 1g8l NO 2 2 C2 C2 11525167 11525167 Interface geometry conserved with 1uz5 (34%) -- Annotation transfered from 1fc5 1g8o PROBNOT 1 1 NPS NPS 11179209 11179209 Paper says: So far, dimerization of soluble α3GalT has not been reported; it has been proposed that different glycosyltransferases may form non-covalent oligomers during Golgi sorting/trafficking. It is conceivable that the homologous UDP-binding subdomain shared by Golgi glycosyltransferases of different specificities (see below) might support their non-covalent association, increasing their efficiency in glycan biosynthesis. 1g8r NO 2 2 C2 C2 11525167 11525167 Interface geometry conserved with 1uz5 (34%) -- Annotation transfered from 1fc5 1g8s PROBYES 2 2 C2 C2 0 10654930 Native gel electrophoresis indicated that Mj0697 dimerizes in solution, suggesting that the interdomain sheet observed in the crystal may be a functional molecular interface. - however this dimer is different from the PISA one, which seems more likely (tighter contacts) 1g8w NO 4 4 D2 D2 11491289 11491289 SP says tetramer -- Annotation transfered from 1fat 1g8x PROBYES 2 1 C2 NPS 11226153 11226153 Paper says: Although the crystallographic asymmetric unit contained two molecules, analysis of the various crystal contacts did not reveal any biologically significant dimerization region - The dimerization region is on the Myosins head, which is not known to dimerize in vivo. 1g8y_1 NO 6 6 C6 C6 11178907 12777796 Paper says hexamer - automatic transfer from 1nlf 1g8y_2 NO 6 6 C6 C6 11178907 12777796 Paper says hexamer - automatic transfer from 1nlf 1g93 PROBNOT 1 1 NPS NPS 11179209 11179209 Paper says: So far, dimerization of soluble α3GalT has not been reported; it has been proposed that different glycosyltransferases may form non-covalent oligomers during Golgi sorting/trafficking. It is conceivable that the homologous UDP-binding subdomain shared by Golgi glycosyltransferases of different specificities (see below) might support their non-covalent association, increasing their efficiency in glycan biosynthesis. -- Annotation transfered from 1g8o 1g98 NO 2 2 C2 C2 11327814 11327814 -- Annotation transfered from 1iat 1g9f YES 4 2 C2 C2 11491289 11491289 I am not sure about this structure, they talk about a dimer in the paper but it probably not correspond to this one. It is either a dimer or a tetramer. This tetramer is wrong anyway - Gives en error in PISA (overlapping structures) 1g9o PROBNOT 1 1 NPS NPS 11352585 11352585 Fragment - this domain mediate interaction with other proteins but no homo-interaction is mentioned in the paper - PISA also says monomer 1g9r PROBNOT 1 1 NPS NPS 11175908 11175908 Paper says: The structure of LgtC is a monomer comprising 286 residues organized into two domains. - No direct evidence provided - PISA says monomer too. 1g9s NO 4 4 D2 D2 12070315 12070315 Analytical ultracentrifugation showed the molecular mass of E. coli HPRT to be 79 kD, confirming that, in solution, E. coli HPRT exists as a tetramer. There was no evidence for the presence of either monomeric or dimeric forms of E. coli HPRT under these conditions. Of the 6-oxopurine PRTase structures currently in the literature, four are tetramers (human HGPRT, T. gondii HGXPRT, E. coli XGPRT, and P. falciparum HGXPRT) and three are dimers (G. lamblia GPRT, T. foetus HGXPRT, and T. cruzi HGPRT). -- Annotation transfered from 1g9t 1g9t NO 4 4 D2 D2 12070315 12070315 Analytical ultracentrifugation showed the molecular mass of E. coli HPRT to be 79 kD, confirming that, in solution, E. coli HPRT exists as a tetramer. There was no evidence for the presence of either monomeric or dimeric forms of E. coli HPRT under these conditions. Of the 6-oxopurine PRTase structures currently in the literature, four are tetramers (human HGPRT, T. gondii HGXPRT, E. coli XGPRT, and P. falciparum HGXPRT) and three are dimers (G. lamblia GPRT, T. foetus HGXPRT, and T. cruzi HGPRT). 1g9u PROBYES 4 1 D2 NPS 11575934 11575934 Paper says: The biological significance of the YopM tetramer is unclear at the present time. Although it occurs in all of the crystal forms of the protein and seems artfully designed, we cannot rule out the possibility that the tetramer is an artifact resulting from the high concentration of calcium in crystallization solutions. Experiments designed to demonstrate oligomerization under more physiological conditions produced contradictory results: size-exclusion chromatography coupled with refractive index/light-scattering measurements indicated that the protein is monomeric in both the absence and presence of 0.8 mM calcium ions -- Annotation transfered from 1jl5 1g9x_1 NO 1 1 NPS NPS 12554933 11470432 Paper says: soluble MJ1267 is monomeric in the absence of nucleotides at protein concentrations up to 0.34 mM - automatic transfer from 1gaj 1g9x_2 NO 1 1 NPS NPS 12554933 11470432 Paper says: soluble MJ1267 is monomeric in the absence of nucleotides at protein concentrations up to 0.34 mM - automatic transfer from 1gaj 1g9x_3 NO 1 1 NPS NPS 12554933 11470432 Paper says: soluble MJ1267 is monomeric in the absence of nucleotides at protein concentrations up to 0.34 mM - automatic transfer from 1gaj 1ga0 PROBNOT 1 1 NPS NPS 11371184 11371184 This is a class C beta Lactamase and those are monomeric (12951239) -- Annotation transfered from 1c3b 1ga5_1 NO 2 2 NS NS 11669620 11669620 Binds direct DNA repeats - automatic transfer from 1hlz 1ga5_2 NO 2 2 NS NS 11669620 11669620 Binds direct DNA repeats - automatic transfer from 1hlz 1ga8 PROBNOT 1 1 NPS NPS 11175908 11175908 Paper says: The structure of LgtC is a monomer comprising 286 residues organized into two domains. - No direct evidence provided - PISA says monomer too. -- Annotation transfered from 1g9r 1ga9_1 PROBNOT 1 1 NPS NPS 11410378 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1ga9_2 PROBNOT 1 1 NPS NPS 11410378 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1gad NO 4 4 D2 D2 8636984 8636984 SP says tetramer - papers too -- Annotation transfered from 1s7c 1gae NO 4 4 D2 D2 8636984 8636984 SP says tetramer - papers too -- Annotation transfered from 1s7c 1gag PROBNOT 1 1 NPS NPS 11135668 11135668 1gaj NO 1 1 NPS NPS 11470432 11470432 Paper says: soluble MJ1267 is monomeric in the absence of nucleotides at protein concentrations up to 0.34 mM 1gal YES 1 2 NPS C2 8421298 8421298 Paper says dimer -- PISA misses it as well -- Annotation transfered from 1cf3 1gam NO 2 2 C2 C2 8605629 8605629 Papers says homodimer and interface conserved to 50% (1ha4) - interesting - very interesting also for gene suplication: 1/ each domain is symmetrical 2/ each chain contains two similar domains 3/chains can form homodimers or paralogous dimers! 1gan NO 2 2 C2 C2 10861929 0 Paper says dimer -- Annotation transfered from 1a78 1gao_1 NO 1 1 NPS NPS 11704670 8132582 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. - automatic transfer from 1frm 1gao_2 NO 1 1 NPS NPS 11704670 8132582 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. - automatic transfer from 1frm 1gao_3 NO 1 1 NPS NPS 11704670 8132582 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. - automatic transfer from 1frm 1gao_4 NO 1 1 NPS NPS 11704670 8132582 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. - automatic transfer from 1frm 1gar PROBYES 2 1 C2 NPS 7776369 7776369 Paper says: E. coli GarTfase exhibits a pH-dependent monomer-dimer equilibrium with the monomer preferably populated above pH 7.4 and the dimer below pH 6.6 -- No info about pH of the final solution but mix 7.5 and 6.3 --> should be around monomer 1gay NO 1 1 NPS NPS 11087397 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gaz NO 1 1 NPS NPS 10913274 10913274 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gb0 NO 1 1 NPS NPS 11087397 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gb2 NO 1 1 NPS NPS 11087397 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gb3 NO 1 1 NPS NPS 11087397 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gb5 NO 1 1 NPS NPS 11087397 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gb6 NO 1 1 NPS NPS 11087397 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gb7 NO 1 1 NPS NPS 11087397 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gb8 NO 1 1 NPS NPS 11087397 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gb9 NO 1 1 NPS NPS 11087397 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gba NO 1 1 NPS NPS 7500345 7500345 9846867 says monomer -- Annotation transfered from 1p05 1gbb NO 1 1 NPS NPS 7500345 7500345 9846867 says monomer -- Annotation transfered from 1p05 1gbc NO 1 1 NPS NPS 7500345 7500345 9846867 says monomer -- Annotation transfered from 1p05 1gbd NO 1 1 NPS NPS 7500345 7500345 9846867 says monomer -- Annotation transfered from 1p05 1gbe NO 1 1 NPS NPS 7500345 7500345 9846867 says monomer -- Annotation transfered from 1p05 1gbf NO 1 1 NPS NPS 7500345 7500345 9846867 says monomer -- Annotation transfered from 1p05 1gbh NO 1 1 NPS NPS 7500345 7500345 9846867 says monomer -- Annotation transfered from 1p05 1gbi NO 1 1 NPS NPS 7500345 7500345 9846867 says monomer -- Annotation transfered from 1p05 1gbj NO 1 1 NPS NPS 7500345 7500345 9846867 says monomer -- Annotation transfered from 1p05 1gbk NO 1 1 NPS NPS 7500345 7500345 9846867 says monomer -- Annotation transfered from 1p05 1gbl NO 1 1 NPS NPS 7500345 7500345 9846867 says monomer -- Annotation transfered from 1p05 1gbm NO 1 1 NPS NPS 7500345 7500345 9846867 says monomer -- Annotation transfered from 1p05 1gbn YES 3 2 NS C2 9309222 9309222 Cannot possibly be this assembly - the active entity is a dimer -- Annotation transfered from 2can 1gbo NO 1 1 NPS NPS 11087397 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gbt PROBNOT 1 1 NPS NPS 2252895 2252895 -- Annotation transfered from 1az8 1gbw NO 1 1 NPS NPS 11087397 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gbx NO 1 1 NPS NPS 11087397 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gby NO 1 1 NPS NPS 11087397 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gbz NO 1 1 NPS NPS 11087397 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gc0 NO 4 4 D2 D2 10965031 10965031 Paper says tetramer - but says that dimer is active - interesting example for saying that dimer is functional intermediate 1gc2 NO 4 4 D2 D2 10965031 10965031 Paper says tetramer - but says that dimer is active - interesting example for saying that dimer is functional intermediate -- Annotation transfered from 1gc0 1gc3_1 NO 2 2 C2 C2 11432784 11432784 - automatic transfer from 1gck 1gc3_2 NO 2 2 C2 C2 11432784 11432784 - automatic transfer from 1gck 1gc3_3 NO 2 2 C2 C2 11432784 11432784 - automatic transfer from 1gck 1gc3_4 NO 2 2 C2 C2 11432784 11432784 - automatic transfer from 1gck 1gc4_1 NO 2 2 C2 C2 11432784 11432784 - automatic transfer from 1gck 1gc4_2 NO 2 2 C2 C2 11432784 11432784 - automatic transfer from 1gck 1gc6 PROBNOT 1 1 NPS NPS 10970839 10970839 May exist in equilibrium between monomers and oligomers: 10893267 - interesting -- Annotation transfered from 1gc7 1gc7 PROBNOT 1 1 NPS NPS 10970839 10970839 May exist in equilibrium between monomers and oligomers: 10893267 - interesting 1gca NA 1 2 NPS C2 8240551 8240551 Ecocyc says it forms dimers but I am not sure whether this may require some additional domain like a transmembrane helix? -- Annotation transfered from 1glg 1gcb NO 6 6 D3 D3 7638617 7638617 SP says hexamer and interface geometry conserved with 1cb5 (38%) -- Annotation transfered from 3gcb 1gcd NA 2 1 C2 NPS 1942036 1942036 They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 1gce PROBNOT 1 1 NPS NPS 10441119 10441119 This is a class C beta Lactamase and those are monomeric (12951239) -- Annotation transfered from 1c3b -- Annotation transfered from 1ga0 1gcg NA 1 2 NPS C2 8132630 8132630 Ecocyc says it forms dimers but I am not sure whether this may require some additional domain like a transmembrane helix? -- Annotation transfered from 1glg 1gci NO 1 1 NPS NPS 9753430 9753430 -- Annotation transfered from 1c9n 1gck NO 2 2 C2 C2 11432784 11432784 1gcl NO 4 4 C4 C4 8248779 8248779 Paper says tetramer 1gcm NO 3 3 C3 C3 8072533 8072533 Paper says trimer 1gcn PROBNOT 1 1 NPS NPS 171582 171582 Probably exists in an equilibrium between different forms: also forms a trimer in the crystal lattice but it is different from 1bh0 1gcs PROBNOT 1 1 NPS NPS -1 3052280 y-Crystallins are exclusively monomeric 1gct NA 2 1 C2 NPS 2819046 2819046 They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 1gcu NO 1 1 NPS NPS 11224565 10957639 Paper says: Structurally related proteins utilize this C-terminal sheet in forming oligomeric proteins. In BVR, however, the sheet is fully exposed to a solvent channel in the crystal lattice and the residues comprising the sheet are poorly conserved, consistent with dynamic light-scattering experiments indicating that BVR is monomeric. -- Annotation transfered from 1lc0 1gcy PROBNOT 1 1 NPS NPS 11272837 11272837 SP says monomer 1gd1 NO 4 4 D2 D2 3586018 3586018 SP says homotetramer - papers too -- Annotation transfered from 1npt 1gd6 NO 1 1 NPS NPS 12356308 12356308 1gd9 NO 2 2 C2 C2 11134972 11134972 -- Annotation transfered from 1dju 1gdd PROBNOT 1 1 NPS NPS 7481799 7481799 Normally part of a heterotrimer, so apparently no homo-interaction. 1gde NO 2 2 C2 C2 11134972 11134972 -- Annotation transfered from 1dju 1gdh NO 2 2 C2 C2 8120891 8120891 Interface geometry conserved with 2nad (31%) 1gdi PROBNOT 1 1 NPS NPS 8950274 0 SP says monomer -- Annotation transfered from 2gdm 1gdj PROBNOT 1 1 NPS NPS 7643380 7643380 SP says monomer -- Annotation transfered from 2gdm 1gdk PROBNOT 1 1 NPS NPS -1 0 SP says monomer -- Annotation transfered from 2gdm 1gdl PROBNOT 1 1 NPS NPS 8950274 0 SP says monomer -- Annotation transfered from 2gdm 1gdn PROBNOT 1 1 NPS NPS 11134922 11134922 1gdq PROBNOT 1 1 NPS NPS 11134922 11134922 -- Annotation transfered from 1gdn 1gdr NA 1 1 NPS NPS 8156989 8156989 This monomeric state might be relevant as DNA could be used as a template for binding. 1gdu PROBNOT 1 1 NPS NPS 11134922 11134922 -- Annotation transfered from 1gdn 1gdv PROBYES 1 2 NPS C2 11092924 11092924 Interface geometry conserved with 1cc5 (31%) -- possible interessting model to engineer a dimer! 1gdw NO 1 1 NPS NPS 11455596 11455596 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gdx NO 1 1 NPS NPS 11455596 11455596 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ge0 NO 1 1 NPS NPS 11455596 11455596 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ge1 NO 1 1 NPS NPS 11455596 11455596 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ge2 NO 1 1 NPS NPS 11455596 11455596 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ge3 NO 1 1 NPS NPS 11455596 11455596 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ge4 NO 1 1 NPS NPS 11455596 11455596 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ge5 PROBNOT 1 1 NPS NPS 11223512 11223512 1ge6 PROBNOT 1 1 NPS NPS 11223512 11223512 -- Annotation transfered from 1ge5 1ge7 YES 2 1 C2 NPS 11223512 11223512 Based on inspection of the structure I dont think the contact is true (PISA agrees). 1ge8 NO 3 3 C3 C3 11266590 11266590 1geb PROBNOT 1 1 NPS NPS 11098139 11098139 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1gec PROBNOT 1 1 NPS NPS 7548082 7548082 PISA says monomeric, and family is monomeric 1ged PROBNOT 1 1 NPS NPS 11076941 11076941 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer -- Annotation transfered from 1cmj 1geh NO 10 10 D5 D5 11435112 11435112 Paper says: circular dichroism (CD), and gel permeation chromatography (GPC) showed that Tk-Rubisco maintains its secondary structure and decameric assembly even at high temperatures. 1gei PROBNOT 1 1 NPS NPS 11258878 11258878 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer -- Annotation transfered from 1cmj 1gej PROBNOT 1 1 NPS NPS 11258878 11258878 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer -- Annotation transfered from 1cmj 1gek PROBNOT 1 1 NPS NPS 11258878 11258878 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1gem PROBNOT 1 1 NPS NPS 11258878 11258878 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1gen PROBNOT 1 1 NPS NPS 7583664 7583664 Fragment - paper says nothing, PISA says monomer 1ger NO 2 2 C2 C2 8061609 8061609 Paper says dimer 1ges NO 2 2 C2 C2 7833810 7833810 Paper says dimer -- Annotation transfered from 1ger 1get NO 2 2 C2 C2 7833810 7833810 Paper says dimer -- Annotation transfered from 1ger 1geu NO 2 2 C2 C2 7833810 7833810 Paper says dimer -- Annotation transfered from 1ger 1gev NO 1 1 NPS NPS 11294653 11294653 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gew NO 2 2 C2 C2 11294630 11294630 -- Annotation transfered from 1fg3 1gex NO 2 2 C2 C2 11294630 11294630 -- Annotation transfered from 1fg3 1gey NO 2 2 C2 C2 11294630 11294630 -- Annotation transfered from 1fg3 1gez NO 1 1 NPS NPS 11294653 11294653 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gf0 NO 1 1 NPS NPS 11294653 11294653 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gf3 NO 1 1 NPS NPS 11294653 11294653 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gf4 NO 1 1 NPS NPS 11294653 11294653 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gf5 NO 1 1 NPS NPS 11294653 11294653 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gf6 NO 1 1 NPS NPS 11294653 11294653 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gf7 NO 1 1 NPS NPS 11294653 11294653 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gf8 NO 1 1 NPS NPS 11927576 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gf9 NO 1 1 NPS NPS 11927576 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gfa NO 1 1 NPS NPS 11927576 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gfe NO 1 1 NPS NPS 11927576 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gfg NO 1 1 NPS NPS 11927576 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gfh NO 1 1 NPS NPS 11927576 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gfi PROBNOT 1 1 NPS NPS 8073283 8073283 Normally part of a heterotrimer, so apparently no homo-interaction. -- Annotation transfered from 1gdd 1gfj NO 1 1 NPS NPS 11927576 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gfk NO 1 1 NPS NPS 11927576 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gfl PROBNOT 2 2 C2 C2 9631087 9631087 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 2emo 1gfm NO 3 3 C3 C3 8702816 8702816 Interface geometry conserved with 1prn (20%) -- Annotation transfered from 1gfn 1gfn NO 3 3 C3 C3 8702816 8702816 Interface geometry conserved with 1prn (20%) 1gfo NO 3 3 C3 C3 8702816 8702816 Interface geometry conserved with 1prn (20%) -- Annotation transfered from 1gfn 1gfp NO 3 3 C3 C3 8702816 8702816 Interface geometry conserved with 1prn (20%) -- Annotation transfered from 1gfn 1gfq NO 3 3 C3 C3 8702816 8702816 Interface geometry conserved with 1prn (20%) -- Annotation transfered from 1gfn 1gfr NO 1 1 NPS NPS 11927576 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gfs NO 2 2 C2 C2 9862812 9862812 SP and paper say dimer -- Annotation transfered from 1e7s 1gft NO 1 1 NPS NPS 11927576 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gfu NO 1 1 NPS NPS 11927576 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gfv NO 1 1 NPS NPS 11927576 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1gfy PROBNOT 1 1 NPS NPS 10748206 10748206 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1gfz NO 2 2 C2 C2 10924512 10924512 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1gg0 NO 4 4 D2 D2 10926505 10926505 paper says homotetramer -- Annotation transfered from 1d9e 1gg1 NO 4 4 D2 D2 10926516 10926516 Interface geometry similar to 1oab (57%) -- Annotation transfered from 1qr7 1gg5_1 NO 2 2 C2 C2 11587640 11587640 BU changed since last release and is now corrected - - automatic transfer from 1h66_2 1gg5_2 NO 2 2 C2 C2 11587640 11587640 BU changed since last release and is now corrected - - automatic transfer from 1h66_2 1gg8 NO 2 2 C2 C2 8180201 8180201 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1ggg YES 2 1 NS NPS 8831790 8831790 EcoCyc says monomer 1ggn NO 2 2 C2 C2 11741774 11741774 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1ggo YES 2 2 C2 C2 10995759 10995759 Dimer but wrong interface, the right form is found in 1dik -- problem is PISA does not give the right one -- Annotation transfered from 2dik 1ggt YES 2 2 C2 C2 7913750 7913750 Paper says dimer -- but wrong reconstruction, PISa get the good interface but makes a tetramer 1ggu NO 2 2 C2 C2 9988734 9988734 Paper says dimer -- but wrong reconstruction, PISa get the good interface but makes a tetramer -- Annotation transfered from 1ggt 1ggx NO 4 4 D2 D2 11101896 11101896 Paper says tetramer 1ggy NO 2 2 C2 C2 9988734 9988734 Paper says dimer -- but wrong reconstruction, PISa get the good interface but makes a tetramer -- Annotation transfered from 1ggt 1ggz PROBNOT 1 1 NPS NPS 12067719 12067719 Close monomeric homologs, PISA says monomer 1gh2 PROBNOT 1 1 NPS NPS 11985582 11985582 Paper says: Furthermore, the hTRXL-N crystal structure (this one) is monomeric while hTRX is dimeric in its four crystal structures (reduced, oxidized, C73S and C32S/C35S mutants) reported to date. 1gh4 PROBNOT 1 1 NPS NPS 12460575 12460575 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1o2e 1gha NA 4 1 C2 NPS -1 0 BU changed since last release and is now incorrect - They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 1ghb NA 2 1 C2 NPS -1 0 They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 1ghi PROBNOT 1 1 NPS NPS 11327855 11327855 1ghm PROBNOT 1 1 NPS NPS 11327855 11327855 -- Annotation transfered from 1ghi 1ghp PROBNOT 1 1 NPS NPS 11327855 11327855 -- Annotation transfered from 1ghi 1ghr PROBNOT 1 1 NPS NPS 8146192 9452466 BU changed since last release and is now corrected - Paper says: Space group and unit cell dimensions are consistent with the presence of two protein molecules per asymmetric unit. does not mention an oligomer. - automaticaly inferred from 1aq0 1ghz PROBNOT 1 1 NPS NPS 11292354 11292354 -- Annotation transfered from 1az8 1gi0 PROBNOT 1 1 NPS NPS 11292354 11292354 -- Annotation transfered from 1az8 1gi1 PROBNOT 1 1 NPS NPS 11292354 11292354 -- Annotation transfered from 1az8 1gi2 PROBNOT 1 1 NPS NPS 11292354 11292354 -- Annotation transfered from 1az8 1gi3 PROBNOT 1 1 NPS NPS 11292354 11292354 -- Annotation transfered from 1az8 1gi4 PROBNOT 1 1 NPS NPS 11292354 11292354 -- Annotation transfered from 1az8 1gi5 PROBNOT 1 1 NPS NPS 11292354 11292354 -- Annotation transfered from 1az8 1gi6 PROBNOT 1 1 NPS NPS 11292354 11292354 -- Annotation transfered from 1az8 1gia PROBNOT 1 1 NPS NPS 8073283 8073283 Normally part of a heterotrimer, so apparently no homo-interaction. -- Annotation transfered from 1gdd 1gic NO 4 4 D2 D2 15299735 0 SP says tetramer -- Annotation transfered from 1cjp 1gih NO 1 1 NPS NPS 11335721 11335721 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1gii NO 1 1 NPS NPS 11335721 11335721 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1gij NO 1 1 NPS NPS 11335721 11335721 Cdks do not in general form homo-oligomers 1gik PROBNOT 1 1 NPS NPS 12615543 12615543 PISA says monomeric 1gil PROBNOT 1 1 NPS NPS 8073283 8073283 Normally part of a heterotrimer, so apparently no homo-interaction. -- Annotation transfered from 1gdd 1gis PROBNOT 1 1 NPS NPS 12874371 0 No info, PISA says monomer -- Annotation transfered from 1mrk 1git PROBNOT 1 1 NPS NPS 8939752 8939752 Normally part of a heterotrimer, so apparently no homo-interaction. -- Annotation transfered from 1gdd 1giu PROBNOT 1 1 NPS NPS 12874371 0 No info, PISA says monomer -- Annotation transfered from 1mrk 1gj6 PROBNOT 1 1 NPS NPS 11731301 11731301 -- Annotation transfered from 1az8 1gjm PROBNOT 1 1 NPS NPS -1 0 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1gjn NO 1 1 NPS NPS 11935353 11935353 Myoglobin is well known to be monomeric 1gjo PROBYES 4 1 D2 NPS 0 0 BU changed since last release and is now incorrect - No paper - Tyrosine kinase receptor, so dimeriization is triggered by ligand binding but monomeric form exists 1gjp NO 8 8 D4 D4 11513881 11513881 BU changed since last release and is now corrected - Paper says octamer -- Annotation transfered from 1h7o 1gjr NO 1 1 NPS NPS 12079352 12079352 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1gjv YES 1 2 NPS C2 11562470 11562470 Interface geometry conserved with 1jm6 (36%) 1gjy_1 NA 2 2 C2 C2 11922676 11922676 BU changed since last release and is now corrected - They say that they find tetramers but it is difficult to know if it corresponds to this one 1gjy_2 NA 2 2 C2 C2 11922676 11922676 BU changed since last release and is now corrected - They say that they find tetramers but it is difficult to know if it corresponds to this one 1gk2 NO 4 4 D2 D2 11796111 11796111 Paper says: the chain fold topology is similar to that of a family of tetrameric enzymes catalyzing the elimination of various groups from carboxylic acids, as for instance a hydroxyl by fumarase, ammonia by aspartase, or a guanidino group by argininosuccinate lyase. The avian eye lens protein -crystallin also belongs to this family as an inactive form of the latter enzyme. None of the sequences of these proteins is detectably homologous to histidase or phenylalanine ammonia-lyase. - interesting: have a look wether interface geometry is conserved or not -- Annotation transfered from 1b8f 1gk3 NO 4 4 D2 D2 11796111 11796111 BU changed since last release and is now corrected - Clear homo-tetramer (ch. 1b8f) -- Annotation transfered from 1gkm 1gk4_1 NO 2 2 C2 C2 11889032 11889032 BU changed since last release and is now corrected - Paper says dimer 1gk4_2 NO 2 2 C2 C2 11889032 11889032 BU changed since last release and is now corrected - Paper says dimer 1gk4_3 NO 2 2 C2 C2 11889032 11889032 BU changed since last release and is now corrected - Paper says dimer 1gkb NO 4 4 D2 D2 0 0 SP says tetramer -- Annotation transfered from 1cjp 1gkc_1 PROBNOT 1 1 NPS NPS 12051944 12051944 BU changed since last release and is now corrected - MMP9 appears to be able to form homodimers -- Annotation transfered from 1gkd 1gkc_2 PROBNOT 1 1 NPS NPS 12051944 12051944 BU changed since last release and is now corrected - MMP9 appears to be able to form homodimers -- Annotation transfered from 1gkd 1gkd PROBNOT 2 1 C2 NPS 12051944 12051944 MMP9 appears to be able to form homodimers 1gke NO 4 4 D2 D2 9511961 9511961 Paper says tetramer 1gki NO 6 6 C6 C6 11214325 11214325 BU changed since last release and is now corrected - Paper says: Six equivalent protein monomers associate to form an almost spherical quaternary structure that is strikingly similar to F1-ATPase - automatic transfer from 1e9s_2 1gkj NO 4 4 D2 D2 11895450 11895450 BU changed since last release and is now corrected - Clear homo-tetramer (ch. 1b8f) -- Annotation transfered from 1gkm 1gkk_1 NA 1 2 NPS C2 11738044 11738044 BU changed since last release and is now incorrect - Paper says nothing - email sent -- Annotation transfered from 1gkl 1gkk_2 NA 1 2 NPS C2 11738044 11738044 BU changed since last release and is now incorrect - Paper says nothing - email sent -- Annotation transfered from 1gkl 1gkl_1 NA 1 2 NPS C2 11738044 11738044 BU changed since last release and is now incorrect - Paper says nothing - email sent 1gkl_2 NA 1 2 NPS C2 11738044 11738044 BU changed since last release and is now incorrect - Paper says nothing - email sent 1gkm NO 4 4 D2 D2 11895450 11895450 BU changed since last release and is now corrected - Clear homo-tetramer (ch. 1b8f) 1gko_1 YES 2 2 C2 D2 11560492 11560492 BU changed since last release and is now incorrect - The two dimers do not contact each others! 1gko_2 YES 2 2 C2 D2 11560492 11560492 BU changed since last release and is now incorrect - The two dimers do not contact each others! 1gkp YES 6 4 NS D2 12079340 12079340 Interface geometry conserved with 1nfg (40%) 1gkq NO 4 4 D2 D2 12079340 12079340 Interface geometry conserved with 1nfg (40%) 1gkr NO 4 4 D2 D2 12093275 12093275 Interface geometry conserved with 1nfg (33%) 1gku NA 1 1 NPS NPS 11823434 11823434 Ask Daniela 1gkx YES 1 2 NPS C2 11562470 11562470 Interface geometry conserved with 1jm6 (36%) -- Annotation transfered from 1gjv 1gky PROBNOT 1 1 NPS NPS 1314905 1314905 Paper says nothing, SP and PISA say monomer -- Annotation transfered from 1ex7 1gkz YES 1 2 NPS C2 11562470 11562470 Interface geometry conserved with 1jm6 (36%) -- Annotation transfered from 1gjv 1gl3 NO 2 2 C2 C2 11724560 11724560 -- Annotation transfered from 1t4b 1gl6 NO 6 6 C6 C6 11214325 11214325 BU changed since last release and is now corrected - Paper says: Six equivalent protein monomers associate to form an almost spherical quaternary structure that is strikingly similar to F1-ATPase - automatic transfer from 1e9s_2 1gl7 NO 6 6 C6 C6 11214325 11214325 BU changed since last release and is now corrected - Paper says: Six equivalent protein monomers associate to form an almost spherical quaternary structure that is strikingly similar to F1-ATPase - automatic transfer from 1e9s_2 1gl9_1 NA 1 2 NPS NS 11823434 11823434 BU changed since last release and is now incorrect - Ask Daniela 1gl9_2 NA 1 2 NPS NS 11823434 11823434 BU changed since last release and is now incorrect - Ask Daniela 1glf NO 4 4 D2 D2 9817843 9817843 The enzyme exists in solution as functional dimers that associate reversibly to form tetramers - Dimer tetramer equilibrium -- Annotation transfered from 1bu6 1glg NA 1 2 NPS C2 8161535 0 Ecocyc says it forms dimers but I am not sure whether this may require some additional domain like a transmembrane helix? 1glj NO 2 2 C2 C2 10090737 10090737 Mutation introduced to prevent tetramer formation - Escherichia coli glycerol kinase (GK) displays half-of-the-sites reactivity toward ATP and allosteric regulation by fructose 1, 6-bisphosphate (FBP), which has been shown to promote dimer-tetramer assembly and to inhibit only tetramers. To probe the role of tetramer assembly, a mutation (Ser58-->Trp) was designed to sterically block formation of the dimer-dimer interface near the FBP binding site [Ormo, M., Bystrom, C., and Remington, S. J. (1998) Biochemistry 37, 16565-16572]. The substitution did not substantially change the Michaelis constants or alter allosteric regulation of GK by a second effector, the phosphocarrier protein IIAGlc; however, it eliminated FBP inhibition. - - interesting to show that in some cases we have no clue what QS is useful for. 1gll NO 2 2 C2 C2 10090737 10090737 Mutation introduced to prevent tetramer formation - Escherichia coli glycerol kinase (GK) displays half-of-the-sites reactivity toward ATP and allosteric regulation by fructose 1, 6-bisphosphate (FBP), which has been shown to promote dimer-tetramer assembly and to inhibit only tetramers. To probe the role of tetramer assembly, a mutation (Ser58-->Trp) was designed to sterically block formation of the dimer-dimer interface near the FBP binding site [Ormo, M., Bystrom, C., and Remington, S. J. (1998) Biochemistry 37, 16565-16572]. The substitution did not substantially change the Michaelis constants or alter allosteric regulation of GK by a second effector, the phosphocarrier protein IIAGlc; however, it eliminated FBP inhibition. - - interesting to show that in some cases we have no clue what QS is useful for. -- Annotation transfered from 1glj 1glo PROBNOT 1 1 NPS NPS 11856830 0 SP says monomer -- Annotation transfered from 1nqc 1glp NO 2 2 C2 C2 8145243 8145243 -- Annotation transfered from 1bay 1glq NO 2 2 C2 C2 8145243 8145243 -- Annotation transfered from 1bay 1glu NO 2 2 C2 C2 1865905 1865905 Interface geometry conserved with 1r4i (73% id). -- Annotation transfered from 1r4r 1glv YES 1 4 NPS D2 8445637 8445637 Paper says tetramer -- PISA error, does not find it. 1gm4 NO 1 1 NPS NPS 11551953 11551953 Paper says: Tetraheme cytochrome c(3) is a small soluble and monomeric protein that performs a central step in the bioenergetic metabolism of sulfate reducing bacteria - PISA says monomer too 1gm6 PROBNOT 1 1 NPS NPS 12027882 12027882 Paper says monomeric but no clear evidence is provided 1gmb NO 1 1 NPS NPS 11551953 0 Paper says: Tetraheme cytochrome c(3) is a small soluble and monomeric protein that performs a central step in the bioenergetic metabolism of sulfate reducing bacteria - PISA says monomer too -- Annotation transfered from 1gm4 1gmc NA 4 1 C2 NPS 8003497 8003497 BU changed since last release and is now incorrect - They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 1gmd NA 4 1 C2 NPS 8003497 8003497 BU changed since last release and is now incorrect - They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 1gmg_1 NO 2 2 C2 C2 0 0 BU changed since last release and is now corrected - 1gmg_2 NO 2 2 C2 C2 0 0 BU changed since last release and is now corrected - 1gmh NA 2 1 NPS NPS 1942036 3980476 BU changed since last release and is now incorrect - They explain in the paper (3980476) that chymotrypsin can form an asymetric dimer, but can also be found as a monomer in particular conditions. Here PISA says monomer. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 1ex3 1gmi PROBNOT 1 1 NPS NPS 11518534 11518534 PISA says monomer 1gml_1 YES 2 1 C2 NPS 12083524 12083524 BU changed since last release and is now incorrect - Paper says mostly monomeric: Although the protein is predominantly monomeric in solution, a fraction of 5–10% was detected as dimer in gel filtration chromatography and both crystal forms have an essentially identical dimer with 2-fold symmetry as the fundamental unit - monomer - dimer equilibrium 1gml_2 YES 2 1 C2 NPS 12083524 12083524 BU changed since last release and is now incorrect - Paper says mostly monomeric: Although the protein is predominantly monomeric in solution, a fraction of 5–10% was detected as dimer in gel filtration chromatography and both crystal forms have an essentially identical dimer with 2-fold symmetry as the fundamental unit - monomer - dimer equilibrium 1gmp YES 2 1 NS NPS 15299531 0 11969396 says monomer 1gmq_1 PROBNOT 1 1 NPS NPS 15299531 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1gmq_2 PROBNOT 1 1 NPS NPS 15299531 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1gmr YES 2 1 NS NPS 15299531 0 11969396 says monomer -- Annotation transfered from 1gmp 1gmy_1 NO 1 1 NPS NPS 11741472 0 BU changed since last release and is now corrected - SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) 1gmy_2 NO 1 1 NPS NPS 11741472 0 BU changed since last release and is now corrected - SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) 1gmy_3 NO 1 1 NPS NPS 11741472 0 BU changed since last release and is now corrected - SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) 1gmz NO 2 2 C2 C2 12554936 0 BU changed since last release and is now corrected - Form where the active site is hidden (seen with PISA). Similar form is found in 1gp7 even though seq id = 44% - interesting 1gn1_1 YES 2 1 C2 NPS 12083524 12083524 BU changed since last release and is now incorrect - Paper says mostly monomeric: Although the protein is predominantly monomeric in solution, a fraction of 5–10% was detected as dimer in gel filtration chromatography and both crystal forms have an essentially identical dimer with 2-fold symmetry as the fundamental unit - monomer - dimer equilibrium 1gn1_2 YES 2 1 C2 NPS 12083524 12083524 BU changed since last release and is now incorrect - Paper says mostly monomeric: Although the protein is predominantly monomeric in solution, a fraction of 5–10% was detected as dimer in gel filtration chromatography and both crystal forms have an essentially identical dimer with 2-fold symmetry as the fundamental unit - monomer - dimer equilibrium 1gn1_3 YES 2 1 C2 NPS 12083524 12083524 BU changed since last release and is now incorrect - Paper says mostly monomeric: Although the protein is predominantly monomeric in solution, a fraction of 5–10% was detected as dimer in gel filtration chromatography and both crystal forms have an essentially identical dimer with 2-fold symmetry as the fundamental unit - monomer - dimer equilibrium 1gn1_4 YES 2 1 C2 NPS 12083524 12083524 BU changed since last release and is now incorrect - Paper says mostly monomeric: Although the protein is predominantly monomeric in solution, a fraction of 5–10% was detected as dimer in gel filtration chromatography and both crystal forms have an essentially identical dimer with 2-fold symmetry as the fundamental unit - monomer - dimer equilibrium 1gn2_1 NO 4 4 D2 D2 11747311 11747311 BU changed since last release and is now corrected - 1gn2_2 NO 4 4 D2 D2 11747311 11747311 BU changed since last release and is now corrected - 1gn3 NO 4 4 D2 D2 9490054 9490054 BU changed since last release and is now corrected - Clear tetramer -- Very interesting, same geometry but the interface is quite different from the human and thermophil ones, which are also different from each others. - very interesting for interface evolution!! --> very versatile 1gn4 NO 4 4 D2 D2 9490054 9490054 Paper says tetramer, SP too -- Annotation transfered from 1ids 1gn6 NO 4 4 D2 D2 8674528 8674528 Paper says tetramer, SP too -- Annotation transfered from 1ids 1gn8 PROBNOT 6 6 D3 D3 11812124 0 BU changed since last release and is now corrected - This paper (which does not correpond to this particular structure) says it is a hexamer -- Annotation transfered from 1qjc 1gne NO 2 2 C2 C2 7538846 7538846 -- Annotation transfered from 1bg5 1gnk YES 6 3 NS C3 9733647 9733647 Paper says: The trimers formed by native GlnK (Figure 2) and the GlnK/ATP complex are basically the same. 1gnm NO 2 2 C2 C2 8718851 8718851 -- Annotation transfered from 1ajx 1gnn NO 2 2 C2 C2 8718851 8718851 -- Annotation transfered from 1ajx 1gno NO 2 2 C2 C2 8718851 8718851 -- Annotation transfered from 1ajx 1gnp PROBYES 2 1 C2 NPS 7473708 7473708 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 1gnq PROBYES 2 1 C2 NPS 7473708 7473708 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 1gnr PROBYES 2 1 C2 NPS 7473708 7473708 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 1gns NO 1 1 NPS NPS 12011071 12011071 -- Annotation transfered from 1yja 1gnu PROBNOT 1 1 NPS NPS 11729197 11729197 Paper mentions gel filtration and no oligomer - PISA says monomer 1gnv NO 1 1 NPS NPS 12011071 12011071 -- Annotation transfered from 1yja 1gnw NO 2 2 C2 C2 8551521 8551521 -- Annotation transfered from 1bx9 1gnx NA 2 2 C2 C2 0 0 No paper 1gnz YES 1 4 NPS D2 11714720 11714720 Paper says tetramer 1go2 NO 1 1 NPS NPS 15789405 0 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1goa PROBNOT 1 1 NPS NPS 8393706 8393706 SP says monomer -- Annotation transfered from 1f21 1gob PROBNOT 1 1 NPS NPS 8393706 8393706 SP says monomer -- Annotation transfered from 1f21 1goc PROBNOT 1 1 NPS NPS 8393706 8393706 SP says monomer -- Annotation transfered from 1f21 1god NA 1 1 NPS NPS 10356281 10356281 Lys 49 ... shouldnt form dimers? 1goj NO 1 1 NPS NPS 11707393 11707393 Missing dimerization coil-coil 1gol PROBNOT 1 1 NPS NPS 8639522 8639522 -- Annotation transfered from 4erk 1gon_1 NA 1 2 NPS C2 0 0 BU changed since last release and is now incorrect - No paper -- Annotation transfered from 1gnx 1gon_2 NA 1 2 NPS C2 0 0 BU changed since last release and is now incorrect - No paper -- Annotation transfered from 1gnx 1gos NO 2 2 C2 C2 11753429 11753429 Paper says dimer 1gou_1 PROBYES 1 2 NPS C2 11976484 11976484 BU changed since last release and is now incorrect - Paper says: The side chain of Phe81 of molecule A partly occupies the guanine base binding site of molecule B. Accordingly, the nucleotide is observed only in molecule A of the binase-3 GMP complex. [...]. The presence of a binase dimer in solution has been also demonstrated by Panov (1995). -- note: symmetry calculation error -- Annotation transfered from 1gov 1gou_2 PROBYES 1 2 NPS C2 11976484 11976484 BU changed since last release and is now incorrect - Paper says: The side chain of Phe81 of molecule A partly occupies the guanine base binding site of molecule B. Accordingly, the nucleotide is observed only in molecule A of the binase-3 GMP complex. [...]. The presence of a binase dimer in solution has been also demonstrated by Panov (1995). -- note: symmetry calculation error -- Annotation transfered from 1gov 1gov_1 PROBYES 1 2 NPS C2 11976484 11976484 BU changed since last release and is now incorrect - Paper says: The side chain of Phe81 of molecule A partly occupies the guanine base binding site of molecule B. Accordingly, the nucleotide is observed only in molecule A of the binase-3 GMP complex. [...]. The presence of a binase dimer in solution has been also demonstrated by Panov (1995). -- note: symmetry calculation error 1gov_2 PROBYES 1 2 NPS C2 11976484 11976484 BU changed since last release and is now incorrect - Paper says: The side chain of Phe81 of molecule A partly occupies the guanine base binding site of molecule B. Accordingly, the nucleotide is observed only in molecule A of the binase-3 GMP complex. [...]. The presence of a binase dimer in solution has been also demonstrated by Panov (1995). -- note: symmetry calculation error 1gow PROBNOT 4 4 D2 D2 9299327 9299327 The enzyme is a tetramer with subunit molecular mass at 60 kDa 1goy_1 PROBYES 1 2 NPS C2 11976484 11976484 BU changed since last release and is now incorrect - Paper says: The side chain of Phe81 of molecule A partly occupies the guanine base binding site of molecule B. Accordingly, the nucleotide is observed only in molecule A of the binase-3 GMP complex. [...]. The presence of a binase dimer in solution has been also demonstrated by Panov (1995). -- note: symmetry calculation error -- Annotation transfered from 1gov 1goy_2 PROBYES 1 2 NPS C2 11976484 11976484 BU changed since last release and is now incorrect - Paper says: The side chain of Phe81 of molecule A partly occupies the guanine base binding site of molecule B. Accordingly, the nucleotide is observed only in molecule A of the binase-3 GMP complex. [...]. The presence of a binase dimer in solution has been also demonstrated by Panov (1995). -- note: symmetry calculation error -- Annotation transfered from 1gov 1goz_1 PROBNOT 1 1 NPS NPS 11704673 11704673 BU changed since last release and is now corrected - SEB is monomeric 1goz_2 PROBNOT 1 1 NPS NPS 11704673 11704673 BU changed since last release and is now corrected - SEB is monomeric 1gp4 PROBNOT 1 1 NPS NPS 11796114 0 No info about olig. state in the paper, PISA says monomer. Given all similar enzymes function as monomers, I ll say it s true. 1gp5 PROBNOT 1 1 NPS NPS 11796114 0 No info about olig. state in the paper, PISA says monomer. Given all similar enzymes function as monomers, I ll say it s true. -- Annotation transfered from 1gp4 1gp6 PROBNOT 1 1 NPS NPS 11796114 0 No info about olig. state in the paper, PISA says monomer. Given all similar enzymes function as monomers, I ll say it s true. -- Annotation transfered from 1gp4 1gp7_1 YES 1 2 NPS C2 12217659 12217659 BU changed since last release and is now incorrect - Again like in the trimer, the active site is burried in the dimer interior - might have a functional relevance 1gp7_2 YES 1 2 NPS C2 12217659 12217659 BU changed since last release and is now incorrect - Again like in the trimer, the active site is burried in the dimer interior - might have a functional relevance 1gp7_3 YES 1 2 NPS C2 12217659 12217659 BU changed since last release and is now incorrect - Again like in the trimer, the active site is burried in the dimer interior - might have a functional relevance 1gpa NO 4 4 D2 D2 1900534 1900534 Paper says: Phosphorylase reconstituted with PLPP is not active, but the modified enzyme exhibits properties the of R-state conformation as detected by high affinity for AMP and aggregation of dimers to tetramers (Withers et al., 1982). -- Annotation transfered from 1abb 1gpb NO 2 2 C2 C2 -1 0 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1gpd YES 8 4 D2 D2 127793 127793 2 copies on each other 1gpe NO 2 2 C2 C2 10216293 10216293 Paper says dimer -- interesting, interface geometry conserved down to 20% (1kdg) 1gpi PROBNOT 1 1 NPS NPS 11743726 11743726 Paper says: produce a dimer in the crystal. For the intact protein in vivo, a linker and CBM would be connected to the C terminus of the catalytic module, and additional sugar groups would be expected to be found at Asn286; both of these factors would be expected to interfere with the formation of a dimer in vivo. 1gpk PROBNOT 1 1 NPS NPS 12196020 12196020 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1gpn PROBNOT 1 1 NPS NPS 12196020 12196020 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1gpr NO 2 2 C2 C2 1447219 0 Interface conserved with 2f3g (42%) 1gpw_1 NO 2 2 NPS NPS 11839304 11839304 BU changed since last release and is now corrected - Paper says h-dimer 1gpw_2 NO 2 2 NPS NPS 11839304 11839304 BU changed since last release and is now corrected - Paper says h-dimer 1gpw_3 NO 2 2 NPS NPS 11839304 11839304 BU changed since last release and is now corrected - Paper says h-dimer 1gpy NO 2 2 C2 C2 8331662 8331662 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1gq1 NO 2 2 C2 C2 0 0 Homodimer -- Annotation transfered from 1h9y 1gq3 NO 3 3 C3 C3 0 0 1gq4 PROBNOT 1 1 NPS NPS 11882663 11882663 Fragment - this domain mediate interaction with other proteins but no homo-interaction is mentioned in the paper - PISA also says monomer -- Annotation transfered from 1g9o 1gq5 PROBNOT 1 1 NPS NPS 11882663 0 Fragment - this domain mediate interaction with other proteins but no homo-interaction is mentioned in the paper - PISA also says monomer -- Annotation transfered from 1g9o 1gq6 NO 6 6 D3 D3 12020346 12020346 BU changed since last release and is now corrected - Paper says: PAH is hexameric in solution 1gq7 NO 6 6 D3 D3 12020346 12020346 Paper says: PAH is hexameric in solution - interface geometry conserved with 1woi (34%) 1gq9 PROBNOT 2 2 C2 C2 11802716 11802716 Paper says dimer : The purified dimeric CKS 1gqa PROBNOT 2 2 C2 C2 0 0 1gqc PROBNOT 2 2 C2 C2 11802716 11802716 Paper says dimer : The purified dimeric CKS -- Annotation transfered from 1gq9 1gqg PROBYES 4 2 C2 C2 12069585 12069585 Paper says dimer: The enzyme is a homodimer of ~100 kDa. 1gqh PROBYES 4 2 C2 C2 12069585 12069585 Paper says dimer: The enzyme is a homodimer of ~100 kDa. -- Annotation transfered from 1gqg 1gqi NO 2 2 C2 C2 11937059 15466046 Homodimer 1gqj NO 2 2 C2 C2 11937059 0 Homodimer -- Annotation transfered from 1gqi 1gqk NO 2 2 C2 C2 11937059 0 Homodimer -- Annotation transfered from 1gqi 1gql NO 2 2 C2 C2 11937059 0 Homodimer -- Annotation transfered from 1gqi 1gqm_1 NO 6 6 D3 D3 11856825 11856825 BU changed since last release and is now corrected - Paper says hexamer which seems to be true - We have confirmed S100A12 oligomerization in solution in the presence of calcium by DLS data, [...] When the calcium concentration is increased to 200 mM, as in the crystallization buffer, the RH decreased to 2.4 nm. This probably means that the dissociation of some hexamers into dimers occurs at such high calcium concentrations and explains the existence of two crystal forms under the same conditions. - low calcium induced hexamerization 1gqm_2 NO 6 6 D3 D3 11856825 11856825 BU changed since last release and is now corrected - Paper says hexamer which seems to be true - We have confirmed S100A12 oligomerization in solution in the presence of calcium by DLS data, [...] When the calcium concentration is increased to 200 mM, as in the crystallization buffer, the RH decreased to 2.4 nm. This probably means that the dissociation of some hexamers into dimers occurs at such high calcium concentrations and explains the existence of two crystal forms under the same conditions. - low calcium induced hexamerization 1gqo YES 24 12 C3 Tetr 0 0 Interface geometry conserved with 1h0s (45%) 1gqp YES 2 1 C2 NPS 11884135 11884135 Paper says: These results indicate that the dimer observed in the crystal lattice is most probably a consequence of crystal packing, and dimers of Doc1/Apc10 do not occur in solution or in the con- text of the APC 1gqr PROBNOT 1 1 NPS NPS 11888271 11888271 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1gqs PROBNOT 1 1 NPS NPS 11888271 11888271 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1gqt_1 NO 2 2 C2 C2 11786021 11786021 BU changed since last release and is now corrected - 1gqt_2 NO 2 2 C2 C2 11786021 11786021 BU changed since last release and is now corrected - 1gqv PROBNOT 1 1 NPS NPS 11876642 11876642 -- Annotation transfered from 1hi2 1gr0 NO 4 4 D2 D2 12005437 0 Paper says tetramer 1gr1 NO 1 1 NPS NPS 12383252 12383252 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1gr2 PROBNOT 1 1 NPS NPS 9804426 9804426 Although the isolated ligand binding core is predominately monomeric in solution, as judged by size-exclusion chromatography and analytical ultracentrifugation, data from other groups on related receptors suggests that the extracellular domains of iGluRs may assemble in dimeric units. Because it is membrane bound, the interaction does not need to be strong so this domain alone in solution is in a monomer dimer equilibrium (thats the way I understand it) - and in these condition it didnt form even a crystalog. dimer 1gr3 NO 3 3 C3 C3 11839302 11839302 BU changed since last release and is now corrected - Interface geometry conserved with 1c28 (47%) 1gr7 PROBYES 4 1 D2 NPS 12007613 12007613 This is hard to believe but it seems that azurin is a monomeric protein! -- Annotation transfered from 5azu 1gra NO 2 2 C2 C2 2585516 2585516 Paper says dimer -- Annotation transfered from 5grt 1grb NO 2 2 C2 C2 2585516 2585516 Paper says dimer -- Annotation transfered from 5grt 1grc PROBNOT 2 2 C2 C2 1522592 1522592 9698564 says: E. coli GarTfase exhibits a pH-dependent monomer-dimer equilibrium with the monomer preferably populated above pH 7.4 and the dimer below pH 6.6 -- pH induced dimerization -- check 12450384 for good summary of the protein 1gre NO 2 2 C2 C2 2585516 2585516 Paper says dimer -- Annotation transfered from 5grt 1grf NO 2 2 C2 C2 2585516 2585516 Paper says dimer -- Annotation transfered from 5grt 1grg NO 2 2 C2 C2 2585516 2585516 Paper says dimer -- Annotation transfered from 5grt 1grl PROBNOT 14 14 D7 D7 7935790 7935790 BU changed since last release and is now corrected - 1grq NO 4 4 D2 D2 11468347 0 BU changed since last release and is now corrected - The enzyme is dimeric in a sulfate-free solution and tetramerization is induced by ammonium sulfate - interesting 1grr NO 4 4 D2 D2 11468347 11468347 BU changed since last release and is now corrected - The enzyme is dimeric in a sulfate-free solution and tetramerization is induced by ammonium sulfate - interesting -- Annotation transfered from 1grq 1grt NO 2 2 C2 C2 9174360 9174360 Paper says dimer -- Annotation transfered from 5grt 1grv YES 2 4 C2 D2 12070315 0 There was no evidence for the presence of either monomeric or dimeric forms of E. coli HPRT under these conditions. Of the 6-oxopurine PRTase structures currently in the literature, four are tetramers (human HGPRT, T. gon-dii HGXPRT, E. coli XGPRT, and P. falciparum HGXPRT) and three are dimers (G. lamblia GPRT, T. foetus HGXPRT, and T. cruzi HGPRT). 1gs3 YES 1 2 NPS C2 0 0 All identical are dimers and PISA says dimer for this one 1gs4 PROBNOT 1 1 NPS NPS 11906285 0 paper does not mention dimer and PISA says monomer -- Annotation transfered from 1e3g 1gs6 NO 3 3 C3 C3 11829502 11829502 BU changed since last release and is now corrected - -- Annotation transfered from 1haw 1gs7 NO 3 3 C3 C3 11829502 11829502 BU changed since last release and is now corrected - -- Annotation transfered from 1haw 1gs8 NO 3 3 C3 C3 11829502 11829502 BU changed since last release and is now corrected - -- Annotation transfered from 1haw 1gsa PROBNOT 4 4 D2 D2 8810901 8810901 SP says homotetramer -- Annotation transfered from 2glt 1gsd_1 NO 2 2 C2 C2 8591048 7892174 BU changed since last release and is now corrected - No structure present? - automatic transfer from 1ags 1gsd_2 NO 2 2 C2 C2 8591048 7892174 BU changed since last release and is now corrected - No structure present? - automatic transfer from 1ags 1gse NO 2 2 C2 C2 8591048 8591048 glutathione S-transferases are functional dimers. -- Annotation transfered from 1pkw 1gsf_1 NO 2 2 C2 C2 8591048 7892174 BU changed since last release and is now corrected - No structure present? - automatic transfer from 1ags 1gsf_2 NO 2 2 C2 C2 8591048 7892174 BU changed since last release and is now corrected - No structure present? - automatic transfer from 1ags 1gsh PROBNOT 4 4 D2 D2 9010922 9010922 SP says homotetramer -- Annotation transfered from 2glt 1gsi NO 2 2 C2 C2 11914484 11914484 BU changed since last release and is now corrected - 1gsk PROBNOT 1 1 NPS NPS 12637519 0 Paper says nothing, PISA says monomer -- Annotation transfered from 1hl0 1gsl NO 2 2 C2 C2 8478943 8478943 the quaternary structure of the molecular dimer is different from that of any other lectin reported to date -- Annotation transfered from 1lec 1gsn NO 2 2 C2 C2 9546215 9546215 Paper says dimer -- Annotation transfered from 5grt 1gsq NO 2 2 C2 C2 7727393 7727393 -- Annotation transfered from 2gsq 1gss NO 2 2 C2 C2 1522586 1522586 -- Annotation transfered from 9gss 1gsu NO 2 2 C2 C2 9571047 9571047 1gsv PROBNOT 1 1 NPS NPS 11714713 0 SP says monomer -- Annotation transfered from 1s1z 1gsw PROBNOT 1 1 NPS NPS 11714713 0 SP says monomer -- Annotation transfered from 1s1z 1gsx PROBNOT 1 1 NPS NPS 11714713 0 SP says monomer -- Annotation transfered from 1s1z 1gsy NO 2 2 C2 C2 8145243 8145243 -- Annotation transfered from 1bay 1gsz PROBYES 3 1 C3 NPS 12031670 12031670 Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer 1gt0 NA 2 4 NPS NPS 0 0 BU changed since last release and is now incorrect - No paper - truncated protein - better remove 1gt1 NO 2 2 C2 C2 15373829 0 Domain Swapped dimer 1gt2 NO 2 2 C2 C2 12581646 12581646 Equilibrium but dimer exists 1gt3 NO 2 2 C2 C2 15373829 0 Domain Swapped dimer -- Annotation transfered from 1gt1 1gt4 NO 2 2 C2 C2 15373829 0 Domain Swapped dimer -- Annotation transfered from 1gt1 1gt5 NO 2 2 C2 C2 15373829 0 Domain Swapped dimer -- Annotation transfered from 1gt1 1gt6 YES 2 1 NS NPS 11895431 11895431 Paper does not mention a dimer and PISA says monomer 1gt7_1 PROBYES 8 4 D4 C4 11976494 11976494 BU changed since last release and is now incorrect - EcoCyc and paper say tetramer 1gt7_2 PROBYES 8 4 C2 C4 11976494 11976494 BU changed since last release and is now incorrect - EcoCyc and paper say tetramer 1gt7_3 PROBYES 8 4 C2 C4 11976494 11976494 BU changed since last release and is now incorrect - EcoCyc and paper say tetramer 1gt7_4 PROBYES 8 4 C2 C4 11976494 11976494 BU changed since last release and is now incorrect - EcoCyc and paper say tetramer 1gt7_5 PROBYES 8 4 C2 C4 11976494 11976494 BU changed since last release and is now incorrect - EcoCyc and paper say tetramer 1gt8_1 NO 2 2 C2 C2 11796730 11796730 BU changed since last release and is now corrected - Paper says: The enzyme is a homodimer of 2 × 111 kDa. -- Annotation transfered from 1gte 1gt8_2 NO 2 2 C2 C2 11796730 11796730 BU changed since last release and is now corrected - Paper says: The enzyme is a homodimer of 2 × 111 kDa. -- Annotation transfered from 1gte 1gt9 NA 2 2 NS NS 12057200 12057200 1gta NO 2 2 C2 C2 7853399 7853399 -- Annotation transfered from 1bg5 1gtb NO 2 2 C2 C2 7853399 7853399 -- Annotation transfered from 1bg5 1gtd NA 4 4 D2 D2 12211007 12211007 No direct evidence and interface of this tetramer is different from the similar tetramer. Sure the real one does not exists in the crystal? -- possible that tetramer geometry not conserved 1gte_1 NO 2 2 C2 C2 11796730 11796730 BU changed since last release and is now corrected - Paper says: The enzyme is a homodimer of 2 × 111 kDa. 1gte_2 NO 2 2 C2 C2 11796730 11796730 BU changed since last release and is now corrected - Paper says: The enzyme is a homodimer of 2 × 111 kDa. 1gtg NA 1 2 NPS NS 12057200 12057200 BU changed since last release and is now incorrect - - automaticaly inferred from 1gt9 1gth_1 NO 2 2 C2 C2 11796730 11796730 BU changed since last release and is now corrected - Paper says: The enzyme is a homodimer of 2 × 111 kDa. -- Annotation transfered from 1gte 1gth_2 NO 2 2 C2 C2 11796730 11796730 BU changed since last release and is now corrected - Paper says: The enzyme is a homodimer of 2 × 111 kDa. -- Annotation transfered from 1gte 1gti_1 NO 2 2 C2 C2 9446594 9446594 - automatic transfer from 1bay 1gti_2 NO 2 2 C2 C2 9446594 9446594 - automatic transfer from 1bay 1gti_3 NO 2 2 C2 C2 9446594 9446594 - automatic transfer from 1bay 1gtj_1 NA 1 2 NPS NS 12057200 12057200 BU changed since last release and is now incorrect - - automaticaly inferred from 1gt9 1gtj_2 NA 1 2 NPS NS 12057200 12057200 BU changed since last release and is now incorrect - - automaticaly inferred from 1gt9 1gtl NA 2 2 NS NS 12057200 12057200 - automatic transfer from 1gt9 1gtv_1 NO 2 2 C2 C2 11914484 11914484 BU changed since last release and is now corrected - supperposed with itself 1gtv_2 NO 2 2 C2 C2 11914484 11914484 BU changed since last release and is now corrected - supperposed with itself 1gtz NO 12 12 Tetr Tetr 11937054 11937054 Interface geometry conserved with 1h0s (43%) -- Annotation transfered from 1gu0 1gu0 NO 12 12 Tetr Tetr 11937054 11937054 Interface geometry conserved with 1h0s (43%) 1gu1 NO 12 12 Tetr Tetr 11937054 11937054 Interface geometry conserved with 1h0s (43%) -- Annotation transfered from 1gu0 1gu2 NA 2 1 NS NPS 16341897 0 Found during the 3D complex curation 1gu7 NO 2 2 C2 C2 12614607 0 Interface geometry conserved with 1guf (22%) -- Annotation transfered from 1guf 1gu8 YES 2 1 NS NPS 11937052 11937052 No trimeric packing 1gu9 YES 12 3 NS C3 11914371 10884617 BU changed since last release and is now incorrect - From the primary citation, equilibrium centrifugation experiments have confirmed that AhpD also exists as a trimer in solution [5] where reference 5 is Slayden, R. A., and Barry, C. E., 3rd (2000) Microbes and Infection 2, 659-669 1gub PROBNOT 1 1 NPS NPS 10064713 0 1gud PROBYES 2 1 C2 NPS 10064713 0 Based on examination of the crystal 1gue PROBNOT 1 1 NPS NPS 11937052 11937052 No trimeric packing -- Annotation transfered from 1h68 1guf NO 2 2 C2 C2 12614607 0 Interface geometry conserved with 1guf (22%) 1gug NO 6 6 D3 D3 11836258 11836258 MopII assembles as a trimer of dimers and binds eight oxyanions at two types of binding sites located at intersubunit interfaces. - From the abstract of the primary citation. -- Annotation transfered from 1gus 1guh_1 NO 2 2 C2 C2 8331657 7892174 BU changed since last release and is now corrected - No structure present? - automatic transfer from 1ags 1guh_2 NO 2 2 C2 C2 8331657 7892174 BU changed since last release and is now corrected - No structure present? - automatic transfer from 1ags 1guk NO 2 2 C2 C2 9498801 9498801 -- Annotation transfered from 1b48 1gun NO 6 6 D3 D3 11836258 11836258 MopII assembles as a trimer of dimers and binds eight oxyanions at two types of binding sites located at intersubunit interfaces. - From the abstract of the primary citation. -- Annotation transfered from 1gus 1guo NO 6 6 D3 D3 11836258 11836258 MopII assembles as a trimer of dimers and binds eight oxyanions at two types of binding sites located at intersubunit interfaces. - From the abstract of the primary citation. -- Annotation transfered from 1gus 1gus NO 6 6 D3 D3 11836258 11836258 MopII assembles as a trimer of dimers and binds eight oxyanions at two types of binding sites located at intersubunit interfaces. - From the abstract of the primary citation. 1gut NO 6 6 D3 D3 11836258 11836258 MopII assembles as a trimer of dimers and binds eight oxyanions at two types of binding sites located at intersubunit interfaces. - From the abstract of the primary citation. -- Annotation transfered from 1gus 1guv NO 1 1 NPS NPS 11960986 0 Monomer: paper says: the enzyme occurs in two major forms of 39 and 50 kDa. The subsequent cloning of its cDNA from a macrophage library showed that the 50-kDa form can be converted to the 39-kDa form post-translationally or by RNA processing -- Annotation transfered from 1hki 1guy NO 4 4 D2 D2 12054817 12054817 BU changed since last release and is now corrected - These MDHs are tetramers and are structurally related to tetrameric malate dehydrogenases from Archaea and to lactate dehydrogenases. 1guz NO 4 4 D2 D2 12054817 12054817 Paper says tetramer 1gv0 NO 4 4 D2 D2 12054817 12054817 BU changed since last release and is now corrected - Paper says tetramer 1gv1 NO 4 4 D2 D2 12054817 12054817 Paper says tetramer -- Annotation transfered from 1guz 1gv3 NO 2 2 C2 C2 12162960 12162960 Cyanobacteria are shown to be unique in containing membrane-bound manganese superoxide dismutases (MnSOD). They are homodimeric type 2 membrane proteins that protect this phototrophic organism against oxidative stress. 1gv4_1 PROBYES 1 2 NPS C2 11967568 11967568 BU changed since last release and is now incorrect - recombinant AIF behaves as a monomer in solution (as determined by analytical ultracentrifugation in the range of micromolar protein concentration, data not shown), AIF could dimerize upon interaction with a putative protein or DNA partner or after post-translational modification. Indeed, an essentially identical dimer was observed in BphA4 crystals (1D7Y and 1F3P < 30% seq id!), a known dimeric protein. 1gv4_2 PROBYES 1 2 NPS C2 11967568 11967568 BU changed since last release and is now incorrect - recombinant AIF behaves as a monomer in solution (as determined by analytical ultracentrifugation in the range of micromolar protein concentration, data not shown), AIF could dimerize upon interaction with a putative protein or DNA partner or after post-translational modification. Indeed, an essentially identical dimer was observed in BphA4 crystals (1D7Y and 1F3P < 30% seq id!), a known dimeric protein. 1gv7 NO 1 1 NPS NPS 12173935 12173935 1gvf NO 4 4 D2 D2 11940603 11940603 BU changed since last release and is now corrected - Paper says tetramer 1gvj PROBNOT 2 2 C2 C2 0 15591056 Furthermore, the similarities between the Domain swapped dimer - normally monomeric, swapped segment can exist in two conformation, turns out that this conformation is compatible with domain swapping. Paper says: intramolecular interactions in Ets-1{Delta}N301 and the intermolecular interactions in crystalline Ets-1{Delta}N300 validate the proposal that the latter represents a three-dimensional domain-swapped dimer with the in trans position of HI-1 recapitulating its in cis position in a monomeric state. 1gvk PROBNOT 1 1 NPS NPS 11896054 11896054 -- Annotation transfered from 1c1m 1gvl PROBNOT 1 1 NPS NPS 12016211 12016211 -- Annotation transfered from 1l2e 1gvo NO 1 1 NPS NPS 11923299 0 PETN reductase is a monomeric flavoenzyme 1gvq NO 1 1 NPS NPS 11923299 0 PETN reductase is a monomeric flavoenzyme -- Annotation transfered from 1gvo 1gvr NO 1 1 NPS NPS 11923299 0 PETN reductase is a monomeric flavoenzyme -- Annotation transfered from 1gvo 1gvs NO 1 1 NPS NPS 11923299 0 PETN reductase is a monomeric flavoenzyme -- Annotation transfered from 1gvo 1gvt PROBNOT 1 1 NPS NPS 12083527 12083527 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1gvu PROBNOT 1 1 NPS NPS 12083527 12083527 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1gvv PROBNOT 1 1 NPS NPS 12083527 12083527 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1gvw PROBNOT 1 1 NPS NPS 12083527 12083527 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1gvx PROBNOT 1 1 NPS NPS 12083527 12083527 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1gvy PROBNOT 1 1 NPS NPS 12203498 0 Paper does not mention oligom. state - PISA says monomer -- Annotation transfered from 1j9y 1gvz PROBNOT 1 1 NPS NPS 12217694 12217694 Paper implies monomer 1gw0 PROBYES 2 1 C2 NPS 12118243 12118243 The crystal structure of the M. albomyces laccase (MaL) shows that the enzyme is a monomer 1gw1 PROBNOT 1 1 NPS NPS 12203498 0 Paper does not mention oligom. state - PISA says monomer -- Annotation transfered from 1j9y 1gw2 PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 7atj 1gw9 NO 4 4 D2 D2 12037300 12037300 BU changed since last release and is now corrected - -- Annotation transfered from 1muw 1gwa PROBNOT 1 1 NPS NPS 12037300 12037300 -- Annotation transfered from 1c1m 1gwc_1 YES 1 2 NPS C2 12033934 12033934 BU changed since last release and is now incorrect - Interface geometry conserved with 1e6b (28%) 1gwc_2 YES 1 2 NPS C2 12033934 12033934 BU changed since last release and is now incorrect - Interface geometry conserved with 1e6b (28%) 1gwc_3 YES 1 2 NPS C2 12033934 12033934 BU changed since last release and is now incorrect - Interface geometry conserved with 1e6b (28%) 1gwd NO 1 1 NPS NPS 12037300 12037300 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1gwe YES 1 4 NPS D2 12454454 12454454 Interface geometry conserved with 1mqf (50% id) -- Annotation transfered from 1gwh 1gwf YES 1 4 NPS D2 12454454 12454454 Interface geometry conserved with 1mqf (50% id) -- Annotation transfered from 1gwh 1gwg NO 24 24 Octa Octa 12037300 12037300 BU changed since last release and is now corrected - Interface geometry conserved with 1lb3 (80%) 1gwh YES 1 4 NPS D2 12454454 12454454 Interface geometry conserved with 1mqf (50% id) 1gwi NA 2 2 C2 C2 12519772 12519772 No info found 1gwn PROBYES 2 1 C2 NPS 12009891 12009891 analytical gel filtration indicates a monomer in solution. 1gwo PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 7atj 1gwq_1 YES 1 2 NPS C2 11937504 0 BU changed since last release and is now incorrect - paper says dimer -- Annotation transfered from 1err 1gwq_2 YES 1 2 NPS C2 11937504 0 BU changed since last release and is now incorrect - paper says dimer -- Annotation transfered from 1err 1gwr_1 YES 1 2 NPS C2 11937504 0 BU changed since last release and is now incorrect - paper says dimer -- Annotation transfered from 1err 1gwr_2 YES 1 2 NPS C2 11937504 0 BU changed since last release and is now incorrect - paper says dimer -- Annotation transfered from 1err 1gws PROBNOT 1 1 NPS NPS 12467575 12467575 Paper does not speak about a dimer but 1846136 finds it as a monomer with gel filtration. -- PISA says dimer (wrong?) SCOP domain architecture error? Seems that the whole family is strange in SCOP: sizes are very different. 1gwt PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 7atj 1gwu PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 7atj 1gwv NA 2 2 C2 C2 12011052 0 Paper does not speak about a dimer - 11179209 says It is conceivable that the homologous UDP-binding subdomain shared by Golgi glycosyltransferases of different specificities might support their non-covalent association, increasing their efficiency in glycan biosynthesis. But no proof provided -- Annotation transfered from 1gx4 1gww NA 2 2 C2 C2 12011052 0 Paper does not speak about a dimer - 11179209 says It is conceivable that the homologous UDP-binding subdomain shared by Golgi glycosyltransferases of different specificities might support their non-covalent association, increasing their efficiency in glycan biosynthesis. But no proof provided -- Annotation transfered from 1gx4 1gwx YES 2 2 NS C2 10198642 10198642 Either dimer or monomer but not not symmetrical dimer -- Annotation transfered from 3gwx 1gwz PROBNOT 1 1 NPS NPS 9774441 9774441 Paper says nothing, SP says monomer and PISA too 1gx0 NA 2 2 C2 C2 12011052 0 Paper does not speak about a dimer - 11179209 says It is conceivable that the homologous UDP-binding subdomain shared by Golgi glycosyltransferases of different specificities might support their non-covalent association, increasing their efficiency in glycan biosynthesis. But no proof provided -- Annotation transfered from 1gx4 1gx2 PROBYES 2 1 C2 NPS 0 0 SP says monomer 1gx4 NA 2 2 C2 C2 12011052 12011052 Paper does not speak about a dimer - 11179209 says It is conceivable that the homologous UDP-binding subdomain shared by Golgi glycosyltransferases of different specificities might support their non-covalent association, increasing their efficiency in glycan biosynthesis. But no proof provided 1gx5 YES 2 1 C2 NPS 11884572 11884572 BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer -- Annotation transfered from 1gx6 1gx6 YES 2 1 C2 NPS 11884572 12438577 BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer 1gx8 PROBNOT 1 1 NPS NPS 12054801 12054801 SP says: Under physiological conditions beta-lactoglobulin exists as an equilibrium mixture of monomeric and dimeric forms -- Annotation transfered from 1gxa 1gx9 PROBYES 2 1 C2 NPS 12054801 12054801 BU changed since last release and is now incorrect - SP says: Under physiological conditions beta-lactoglobulin exists as an equilibrium mixture of monomeric and dimeric forms -- Annotation transfered from 1gxa 1gxa PROBNOT 1 1 NPS NPS 12054801 12054801 SP says: Under physiological conditions beta-lactoglobulin exists as an equilibrium mixture of monomeric and dimeric forms 1gxf NO 2 2 C2 C2 15102853 0 Large interface and closely related dimer -- Annotation transfered from 1bzl 1gxm_1 PROBNOT 1 1 NPS NPS 12221284 0 BU changed since last release and is now corrected - They seem to imply that it is a monomeric protein. PISA also thinks the same. 1gxm_2 PROBNOT 1 1 NPS NPS 12221284 0 BU changed since last release and is now corrected - They seem to imply that it is a monomeric protein. PISA also thinks the same. 1gxn PROBNOT 1 1 NPS NPS 12221284 0 They seem to imply that it is a monomeric protein and PISA agrees. -- Annotation transfered from 1gxo 1gxo PROBNOT 1 1 NPS NPS 12221284 0 They seem to imply that it is a monomeric protein and PISA agrees. 1gxt NA 6 1 D3 NPS 12206761 0 BU changed since last release and is now incorrect - PISA says hexamer, paper nothing ... email sent 1gxu NA 6 1 D3 NPS 12206761 0 BU changed since last release and is now incorrect - PISA says hexamer, paper nothing ... email sent - automatic transfer from 1gxt 1gxw PROBNOT 1 1 NPS NPS 12454500 0 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1gxy PROBYES 2 1 C2 NPS 12270706 0 1gxz PROBYES 2 1 C2 NPS 12270706 0 -- Annotation transfered from 1gxy 1gy0 PROBNOT 1 1 NPS NPS 12270706 12270706 1gy2_1 PROBNOT 1 1 NPS NPS 12079384 8947572 SP says monomer - automatic transfer from 1rcy 1gy2_2 PROBNOT 1 1 NPS NPS 12079384 8947572 SP says monomer - automatic transfer from 1rcy 1gy5 NO 2 2 C2 C2 12065398 12065398 NTF2 eluted with an apparent Mr of 31 kDa consistent with its existing in solution as dimers. -- Annotation transfered from 1oun 1gy6 NO 2 2 C2 C2 12065398 12065398 NTF2 eluted with an apparent Mr of 31 kDa consistent with its existing in solution as dimers. -- Annotation transfered from 1oun 1gy7_1 NO 2 2 C2 C2 12065398 12065398 BU changed since last release and is now corrected - Paper says dimer -- Annotation transfered from 1gyb 1gy7_2 NO 2 2 C2 C2 12065398 12065398 BU changed since last release and is now corrected - Paper says dimer -- Annotation transfered from 1gyb 1gy8 YES 4 2 NS C2 12615316 12615316 Paper says dimer 1gyb_1 NO 2 2 C2 C2 12065398 12065398 BU changed since last release and is now corrected - Paper says dimer 1gyb_2 NO 2 2 C2 C2 12065398 12065398 BU changed since last release and is now corrected - Paper says dimer 1gyc PROBNOT 1 1 NPS NPS 12163489 12163489 Paper implies monomer, PISA agrees 1gyg_1 YES 4 1 NS NPS 12051905 9699639 BU changed since last release and is now incorrect - the molecule is active as a monomer 1gyg_2 YES 3 1 C3 NPS 12051905 9699639 BU changed since last release and is now incorrect - the molecule is active as a monomer 1gyn YES 1 2 NPS C2 12595741 12595741 1gyo NO 2 2 C2 C2 0 12657783 Paper says dimer 1gyp NO 4 4 D2 D2 7578111 7578111 SP says tetramer - papers too -- Annotation transfered from 1a7k 1gyq NO 4 4 D2 D2 10200252 10200252 SP says tetramer - papers too -- Annotation transfered from 1a7k 1gyr YES 3 2 NS C2 12614607 0 Interface geometry conserved with 1v3v (23%) 1gyt_1 NO 6 6 D3 D3 10449417 10449417 BU changed since last release and is now corrected - Paper says: PepA is a homohexamer of 32 symmetry. - interface geometry conserved with 1bll (30%) 1gyt_2 NO 6 6 D3 D3 10449417 10449417 BU changed since last release and is now corrected - Paper says: PepA is a homohexamer of 32 symmetry. - interface geometry conserved with 1bll (30%) 1gyu NO 1 1 NPS NPS 12176391 0 AP1 is tetrameric, this is one domain of one subunit which shoichiometry in the complex is one. -- Annotation transfered from 1gyv 1gyv NO 1 1 NPS NPS 12176391 12176391 AP1 is tetrameric, this is one domain of one subunit which shoichiometry in the complex is one. 1gyw_1 NO 1 1 NPS NPS 12176391 12176391 BU changed since last release and is now corrected - AP1 is tetrameric, this is one domain of one subunit which shoichiometry in the complex is one. 1gyw_2 NO 1 1 NPS NPS 12176391 12176391 BU changed since last release and is now corrected - AP1 is tetrameric, this is one domain of one subunit which shoichiometry in the complex is one. 1gz1 PROBNOT 1 1 NPS NPS 12454501 0 Paper says nothing, PISA says monomer -- Annotation transfered from 1oc6 1gz5 NO 4 4 D2 D2 12498887 12498887 Dimer tetramer equilibrium - Light scattering data show that overexpressed His-tagged OtsA exists as both dimers and tetramers in equilibrium. It is not clear if this has any biological significance, perhaps reflecting the ability of a dimer to interact with the phosphatase OtsB (although in E. coli, OtsA most likely exists as a discrete entity; in some other organisms, such as Saccharomyces cerevisae, OtsA and OtsB are associated into a multicomponent complex [30]) or are merely an overexpression artifact. 1gz6 YES 4 4 C2 C2 12517343 12517343 Paper says dimer -- interesting paper, here too, the domain alone has similar catalytic activity as the full length protein. 1gz7 YES 4 2 NS C2 14499609 10666623 Whereas the triclinic crystal reveals monomeric lip2, the monoclinic crystal contains dimeric lip2. Interesting: one structure - different crystal forms! 1gz8 NO 1 1 NPS NPS 12139449 0 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1gz9 PROBNOT 2 2 C2 C2 12139934 12139934 BU changed since last release and is now corrected - 1gza PROBNOT 1 1 NPS NPS 9038188 9038188 Peroxidases seem to be monomeric in general 1gzb PROBNOT 1 1 NPS NPS 8557120 8557120 Peroxidases seem to be monomeric in general -- Annotation transfered from 1gza 1gzc PROBYES 1 2 NPS C2 12139934 12139934 -- Annotation transfered from 1gz9 1gzd NO 2 2 C2 C2 12402366 12402366 BU changed since last release and is now corrected - Paper says dimer 1gze_1 PROBNOT 1 1 NPS NPS 12029083 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer 1gze_2 PROBNOT 1 1 NPS NPS 12029083 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer 1gze_3 PROBNOT 1 1 NPS NPS 12029083 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer 1gze_4 PROBNOT 1 1 NPS NPS 12029083 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer 1gzf_1 PROBNOT 1 1 NPS NPS 12029083 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer -- Annotation transfered from 1gze 1gzf_2 PROBNOT 1 1 NPS NPS 12029083 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer -- Annotation transfered from 1gze 1gzf_3 PROBNOT 1 1 NPS NPS 12029083 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer -- Annotation transfered from 1gze 1gzf_4 PROBNOT 1 1 NPS NPS 12029083 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer -- Annotation transfered from 1gze 1gzg YES 8 4 D4 D4 12079382 12079382 BU changed since last release and is now incorrect - Paper says octamer 1gzk PROBNOT 1 1 NPS NPS 12086620 0 Paper says nothing about oligomer - PISA says monomer -- Annotation transfered from 1o6l 1gzn PROBNOT 1 1 NPS NPS 12086620 0 Paper says nothing about oligomer - PISA says monomer -- Annotation transfered from 1o6l 1gzo PROBNOT 1 1 NPS NPS 12086620 0 Paper says nothing about oligomer - PISA says monomer -- Annotation transfered from 1o6l 1gzr PROBNOT 1 1 NPS NPS 12135360 12135360 Paper says: Both insulin and hIGF-I bind as monomers to their receptors and display an ability to bind to each others receptors - It says that hIGF-I does not assemble into hexamers 1gzu NO 6 6 D3 D3 11959140 11959140 BU changed since last release and is now corrected - Paper says: Human NMNAT is a symmetric hexamer -- PISA doesnt find it - error -- interesting because again, convergent evolution of hexamer (discussed in the paper), also the family is very versatile (could be a good example to show monomer, dimer, tetramer, and hexamer(s). 1gzv NO 2 2 C2 C2 12402366 12402366 BU changed since last release and is now corrected - Paper says dimer 1gzy PROBNOT 1 1 NPS NPS 12135360 12135360 Paper says: Both insulin and hIGF-I bind as monomers to their receptors and display an ability to bind to each others receptors - It says that hIGF-I does not assemble into hexamers -- Annotation transfered from 1gzr 1gzz PROBNOT 1 1 NPS NPS 12135360 12135360 Paper says: Both insulin and hIGF-I bind as monomers to their receptors and display an ability to bind to each others receptors - It says that hIGF-I does not assemble into hexamers -- Annotation transfered from 1gzr 1h00 NO 1 1 NPS NPS 12941311 0 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1h01 NO 1 1 NPS NPS 12941311 0 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1h02 PROBNOT 1 1 NPS NPS 12135360 12135360 Paper says: Both insulin and hIGF-I bind as monomers to their receptors and display an ability to bind to each others receptors - It says that hIGF-I does not assemble into hexamers -- Annotation transfered from 1gzr 1h03 PROBYES 2 1 C2 NPS 12499389 12499389 From the figures in the paper I understand that it is monomeric - PISA says monomeric too. 1h04 PROBNOT 1 1 NPS NPS 12499389 0 From the figures in the paper I understand that it is monomeric - PISA says monomeric too. -- Annotation transfered from 1uot 1h05 PROBNOT 12 12 Tetr Tetr 12387860 12387860 BU changed since last release and is now corrected - Paper says; Type I enzymes are dimers of 27 kDa subunits which contain an (α/β)8 fold; by contrast type II enzymes are dodecameric with the 16 kDa subunits arranged as tetramers of trimers. Each type II DHQase subunit adopts a flavodoxin-type fold, consisting of a five-stranded parallel β-sheet core flanked by four α-helices - this one is a type II enzyme. -- interesting: same reation and two QSs 1h07 NO 1 1 NPS NPS 12941311 0 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1h08 NO 1 1 NPS NPS 12941311 0 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1h0c YES 1 2 NPS C2 12899834 0 BU changed since last release and is now incorrect - 1h0k NO 2 2 C2 C2 0 0 Interface geometry conserved with 1guf (22%) -- Annotation transfered from 1guf 1h0m_1 PROBYES 2 2 C2 NS 12198141 12198141 BU changed since last release and is now incorrect - Paper says: The structure reveals an asymmetric homodimer, with one monomer longer than the other. 1h0m_2 PROBYES 2 2 C2 NS 12198141 12198141 BU changed since last release and is now incorrect - Paper says: The structure reveals an asymmetric homodimer, with one monomer longer than the other. 1h0r NO 12 12 Tetr Tetr 0 0 Interface geometry conserved with 1uqr (48%) -- Annotation transfered from 1h0s 1h0s NO 12 12 Tetr Tetr 0 0 Interface geometry conserved with 1uqr (48%) 1h0v NO 1 1 NPS NPS 12139449 0 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1h0w NO 1 1 NPS NPS 12139449 0 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1h0x NO 2 2 C2 C2 12198167 12198167 Said in the paper 1h0y NO 2 2 C2 C2 12198167 12198167 BU changed since last release and is now corrected - said in the paper 1h16 NO 2 2 C2 C2 12163496 0 BU changed since last release and is now corrected - Said in the paper -- Annotation transfered from 1h17 1h17 NO 2 2 C2 C2 12163496 0 BU changed since last release and is now corrected - Said in the paper 1h18 NO 2 2 C2 C2 12163496 0 -- Annotation transfered from 3pfl 1h1a PROBYES 2 1 C2 NPS 12653995 12653995 according to the dynamic light scattering measurements, the protein was a monomer. PISA is wrong 1h1b PROBYES 2 1 C2 NPS 12190311 10581030 Neutrophil elastase is a monomeric glycoprotein 1h1c_1 NO 2 2 C2 C2 15007066 0 - automatic transfer from 1uu2 1h1c_2 NO 2 2 C2 C2 15007066 0 - automatic transfer from 1uu2 1h1h NO 1 1 NPS NPS 12356310 12356310 1h1i PROBYES 4 2 C2 C2 12486225 0 Paper says dimer: The enzyme is a homodimer of ~100 kDa. -- Annotation transfered from 1gqg 1h1m PROBYES 4 2 C2 C2 12486225 0 Paper says dimer: The enzyme is a homodimer of ~100 kDa. -- Annotation transfered from 1gqg 1h1t PROBYES 2 6 C2 D3 12837781 0 This paper (which does not correpond to this particular structure) says it is a hexamer -- Annotation transfered from 1qjc 1h1w YES 2 1 C2 NPS 12169624 0 BU changed since last release and is now incorrect - gel filtration studies suggest that PDK1 is monomeric -- Annotation transfered from 1okz 1h1x NO 1 1 NPS NPS 14563209 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1h1y NO 2 2 C2 C2 12547196 0 Paper says: The structure of RPEchl from potato leaves has been elucidated. RPEchl is a hexamer whereas RPEcyt is a dimer in plants, yeast and animals. -- Annotation transfered from 1h1z 1h1z NO 2 2 C2 C2 12547196 12547196 Paper says: The structure of RPEchl from potato leaves has been elucidated. RPEchl is a hexamer whereas RPEcyt is a dimer in plants, yeast and animals. 1h22 PROBNOT 1 1 NPS NPS 12517147 0 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1h23 PROBNOT 1 1 NPS NPS 12517147 0 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1h29_1 NO 1 1 NPS NPS 0 12356749 BU changed since last release and is now corrected - 1846136 finds it as a monomer with gel filtration. 1h29_2 NO 1 1 NPS NPS 0 12356749 BU changed since last release and is now corrected - 1846136 finds it as a monomer with gel filtration. 1h29_3 NO 1 1 NPS NPS 0 12356749 BU changed since last release and is now corrected - 1846136 finds it as a monomer with gel filtration. 1h29_4 NO 1 1 NPS NPS 0 12356749 BU changed since last release and is now corrected - 1846136 finds it as a monomer with gel filtration. 1h2b YES 2 4 C2 D2 12927540 12927540 Need to duplicate the other interaction too 1h2c NO 8 8 D4 D4 12679020 0 BU changed since last release and is now corrected - -- Interesting: the protein is made of 2 domains and forms octameric rings only when the 2 domains are cut. The 2 domains protein is a monomer (1es6). 1h2d NO 8 8 D4 D4 12679020 0 BU changed since last release and is now corrected - Interessting: the protein is made of 2 domains and forms octameric rings only when the 2 domains are cut. The 2 domains protein is a monomer (1es6). 1h2e NO 1 1 NPS NPS 12498792 0 Paper says monomer -- Annotation transfered from 1ebb 1h2f NO 1 1 NPS NPS 12498792 0 Paper says monomer -- Annotation transfered from 1ebb 1h2h PROBNOT 2 2 C2 C2 12496312 0 No paper - PISA says dimer - Note similar structs have more subunits! -- Annotation transfered from 1j5p 1h2i_1 NO 11 11 C11 C11 12370410 0 BU changed since last release and is now corrected - 12191481 says undecamer 1h2i_2 NO 11 11 C11 C11 12370410 0 BU changed since last release and is now corrected - 12191481 says undecamer 1h2k NO 4 4 C2 C2 12446723 0 BU changed since last release and is now corrected - 12432100 says: Furthermore, the structure reveals the presence of a FIH-1 homodimer that forms in solution and is essential for FIH activity. 1h2l YES 4 2 C2 C2 12446723 0 BU changed since last release and is now incorrect - 12432100 says: Furthermore, the structure reveals the presence of a FIH-1 homodimer that forms in solution and is essential for FIH activity. -- Annotation transfered from 1h2n 1h2n NO 2 2 C2 C2 12446723 0 BU changed since last release and is now corrected - 12432100 says: Furthermore, the structure reveals the presence of a FIH-1 homodimer that forms in solution and is essential for FIH activity. 1h2p PROBNOT 1 1 NPS NPS 12499389 0 From the figures in the paper I understand that it is monomeric - PISA says monomeric too. -- Annotation transfered from 1uot 1h2q PROBNOT 1 1 NPS NPS 12499389 0 From the figures in the paper I understand that it is monomeric - PISA says monomeric too. -- Annotation transfered from 1uot 1h34 PROBYES 1 2 NPS C2 12554963 12554963 Paper says dimer and PISA too - similar geometry in 1bpi (50%) 1h35 PROBYES 3 1 C3 NPS 12747780 0 Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer -- Annotation transfered from 1gsz 1h36 PROBYES 3 1 C3 NPS 12747780 0 Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer -- Annotation transfered from 1gsz 1h37 PROBYES 3 1 C3 NPS 12747780 0 Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer -- Annotation transfered from 1gsz 1h39 PROBYES 3 1 C3 NPS 12747780 0 Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer -- Annotation transfered from 1gsz 1h3a PROBYES 3 1 C3 NPS 12747780 0 Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer -- Annotation transfered from 1gsz 1h3b PROBYES 3 1 C3 NPS 12747780 0 Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer -- Annotation transfered from 1gsz 1h3c PROBYES 3 1 C3 NPS 12747780 0 Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer -- Annotation transfered from 1gsz 1h3d NO 6 6 D3 D3 14741209 0 Paper says hexamer -- Annotation transfered from 1q1k 1h3i_1 PROBNOT 1 1 NPS NPS 12372304 12372304 BU changed since last release and is now corrected - PID 12567185 says all SET proteins are monomeric, and all similar crystallized ones are monomeric indeed. This dimer is probably an artifact. 1h3i_2 PROBNOT 1 1 NPS NPS 12372304 12372304 BU changed since last release and is now corrected - PID 12567185 says all SET proteins are monomeric, and all similar crystallized ones are monomeric indeed. This dimer is probably an artifact. 1h3j PROBYES 2 1 NS NPS 12777760 9038188 BU changed since last release and is now incorrect - Peroxidases seem to be monomeric in general - automaticaly inferred from 1gza 1h3m NO 2 2 C2 C2 12595740 0 Paper says dimer: CDP-ME synthetase organizes as a homodimer with each subunit related by a crystallographic two-fold axis - SP says dimer too -- Annotation transfered from 1ini 1h3t NO 2 2 C2 C2 12527303 0 -- Annotation transfered from 1fc1 1h3u NO 2 2 C2 C2 12527303 0 -- Annotation transfered from 1fc1 1h3v NO 2 2 C2 C2 12527303 0 -- Annotation transfered from 1fc1 1h3w YES 1 2 NPS C2 12527303 0 1h3x NO 2 2 C2 C2 12527303 0 -- Annotation transfered from 1fc1 1h3y YES 4 2 C2 C2 12527303 0 1h41 NO 2 2 C2 C2 12654910 0 Homodimer -- Annotation transfered from 1gqi 1h42 NO 1 1 NPS NPS 14500716 0 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1h46 PROBNOT 1 1 NPS NPS 12657782 0 Paper says: produce a dimer in the crystal. For the intact protein in vivo, a linker and CBM would be connected to the C terminus of the catalytic module, and additional sugar groups would be expected to be found at Asn286; both of these factors would be expected to interfere with the formation of a dimer in vivo. -- Annotation transfered from 1gpi 1h49 PROBNOT 2 2 C2 C2 0 0 Paper says: It was unexpected that the E401D as well as C205S and C211S mutations dramatically impaired the assembly of a catalysis-competent homodimer, suggesting novel links between the active site structure and dimer formation. -- Interesting: link between dimer formation and catalysis -- Annotation transfered from 1hxj 1h4a PROBNOT 1 1 NPS NPS 12729747 3052280 y-Crystallins are exclusively monomeric 1h4c PROBNOT 1 1 NPS NPS 0 0 Paper says : The MobA protein has been isolated previously, and it has proved to be monomeric in solution. - Other papers says equilibrium -- Annotation transfered from 1e5k 1h4d PROBNOT 1 1 NPS NPS 0 0 Paper says : The MobA protein has been isolated previously, and it has proved to be monomeric in solution. - Other papers says equilibrium -- Annotation transfered from 1e5k 1h4e PROBNOT 1 1 NPS NPS 0 0 Paper says : The MobA protein has been isolated previously, and it has proved to be monomeric in solution. - Other papers says equilibrium -- Annotation transfered from 1e5k 1h4g PROBYES 2 1 C2 NPS 11526340 0 Structure inspection let think that it is not true contacts, PISA agrees 1h4h PROBYES 4 1 C2 NPS 11526340 0 Almost no contact! 1h4n PROBNOT 1 1 NPS NPS 9398308 9398308 9000633 says monomeric -- Annotation transfered from 1uga 1h4o_1 YES 1 2 NPS C2 11518528 11518528 BU changed since last release and is now incorrect - Interface geometry conserved with 1psq (30%) 1h4o_2 YES 1 2 NPS C2 11518528 11518528 BU changed since last release and is now incorrect - Interface geometry conserved with 1psq (30%) 1h4o_3 YES 1 2 NPS C2 11518528 11518528 BU changed since last release and is now incorrect - Interface geometry conserved with 1psq (30%) 1h4o_4 YES 1 2 NPS C2 11518528 11518528 BU changed since last release and is now incorrect - Interface geometry conserved with 1psq (30%) 1h4o_5 YES 1 2 NPS C2 11518528 11518528 BU changed since last release and is now incorrect - Interface geometry conserved with 1psq (30%) 1h4o_6 YES 1 2 NPS C2 11518528 11518528 BU changed since last release and is now incorrect - Interface geometry conserved with 1psq (30%) 1h4o_7 YES 1 2 NPS C2 11518528 11518528 BU changed since last release and is now incorrect - Interface geometry conserved with 1psq (30%) 1h4o_8 YES 1 2 NPS C2 11518528 11518528 BU changed since last release and is now incorrect - Interface geometry conserved with 1psq (30%) 1h4p YES 2 1 C2 NPS 14730348 14730348 Paper says: However, gel filtration and dynamic light scattering data demonstrate that this protein forms monomers in solution, 1h4r PROBYES 2 1 C2 NPS 11856822 11856822 No info in paper - PISA says monomer 1h4v NO 2 2 C2 C2 11399074 11399074 BU changed since last release and is now corrected - Interface geometry conserved with 1ge0 (42%) 1h4w PROBNOT 1 1 NPS NPS 11827488 11827488 1h4x_1 NO 1 1 NPS NPS 11470435 11470435 BU changed since last release and is now corrected - Paper says: Despite the presence of these dimers in the SpoIIAA(M86V) crystals, we have not observed dimers of either mutant or wild-type SpoIIAA in solution (unpublished data). 1h4x_2 NO 1 1 NPS NPS 11470435 11470435 BU changed since last release and is now corrected - Paper says: Despite the presence of these dimers in the SpoIIAA(M86V) crystals, we have not observed dimers of either mutant or wild-type SpoIIAA in solution (unpublished data). 1h4y_1 NO 1 1 NPS NPS 11470435 11470435 BU changed since last release and is now corrected - Paper says: Despite the presence of these dimers in the SpoIIAA(M86V) crystals, we have not observed dimers of either mutant or wild-type SpoIIAA in solution (unpublished data). 1h4y_2 NO 1 1 NPS NPS 11470435 11470435 BU changed since last release and is now corrected - Paper says: Despite the presence of these dimers in the SpoIIAA(M86V) crystals, we have not observed dimers of either mutant or wild-type SpoIIAA in solution (unpublished data). 1h4z NO 1 1 NPS NPS 11470435 11470435 Paper says: Despite the presence of these dimers in the SpoIIAA(M86V) crystals, we have not observed dimers of either mutant or wild-type SpoIIAA in solution (unpublished data). 1h50 NO 1 1 NPS NPS 11428899 11428899 PETN reductase is a monomeric flavoenzyme -- Annotation transfered from 1gvo 1h51 NO 1 1 NPS NPS 11428899 0 PETN reductase is a monomeric flavoenzyme -- Annotation transfered from 1gvo 1h52 NO 1 1 NPS NPS 11468363 11468363 Human angiogenin is monomeric 1h53 NO 1 1 NPS NPS 11468363 11468363 Human angiogenin is monomeric -- Annotation transfered from 1h52 1h55 PROBNOT 1 1 NPS NPS 12024218 12024218 SP says monomer -- Annotation transfered from 7atj 1h57 PROBNOT 1 1 NPS NPS 12024218 12024218 SP says monomer -- Annotation transfered from 7atj 1h58 PROBNOT 1 1 NPS NPS 12024218 12024218 SP says monomer -- Annotation transfered from 7atj 1h5a PROBNOT 1 1 NPS NPS 12024218 12024218 SP says monomer -- Annotation transfered from 7atj 1h5c PROBNOT 1 1 NPS NPS 12024218 12024218 SP says monomer -- Annotation transfered from 7atj 1h5d PROBNOT 1 1 NPS NPS 12024218 12024218 SP says monomer -- Annotation transfered from 7atj 1h5e PROBNOT 1 1 NPS NPS 12024218 12024218 SP says monomer -- Annotation transfered from 7atj 1h5f PROBNOT 1 1 NPS NPS 12024218 12024218 SP says monomer -- Annotation transfered from 7atj 1h5g PROBNOT 1 1 NPS NPS 12024218 12024218 SP says monomer -- Annotation transfered from 7atj 1h5h PROBNOT 1 1 NPS NPS 12024218 12024218 SP says monomer -- Annotation transfered from 7atj 1h5i PROBNOT 1 1 NPS NPS 12024218 12024218 SP says monomer -- Annotation transfered from 7atj 1h5j PROBNOT 1 1 NPS NPS 12024218 12024218 SP says monomer -- Annotation transfered from 7atj 1h5k PROBNOT 1 1 NPS NPS 12024218 12024218 SP says monomer -- Annotation transfered from 7atj 1h5l PROBNOT 1 1 NPS NPS 12024218 12024218 SP says monomer -- Annotation transfered from 7atj 1h5m PROBNOT 1 1 NPS NPS 12024218 12024218 SP says monomer -- Annotation transfered from 7atj 1h5r NO 4 4 D2 D2 11697907 11697907 Interface geometry conserved with 1lvw (61%) -- Annotation transfered from 1h5t 1h5s NO 4 4 D2 D2 11697907 11697907 Interface geometry conserved with 1lvw (61%) -- Annotation transfered from 1h5t 1h5t NO 4 4 D2 D2 11697907 11697907 Interface geometry conserved with 1lvw (61%) 1h5u NO 2 2 C2 C2 11886794 11886794 BU changed since last release and is now corrected - It is not said in the paper that is forms a monomer and there is a drawing of the protein as a dimer. So it is quite clear that it should be a dimer like all the other ones. 1h5x NO 2 2 C2 C2 0 0 Paper says dimer - interface geometry conserved with 1k38 (37%) -- Annotation transfered from 1h8z 1h5y_1 PROBNOT 1 1 NPS NPS 11679715 11679715 BU changed since last release and is now corrected - 1h5y_2 PROBNOT 1 1 NPS NPS 11679715 11679715 BU changed since last release and is now corrected - 1h5z PROBNOT 1 1 NPS NPS 15530358 0 11304120 says P450s are monomeric enzymes -- Annotation transfered from 1u13 1h60 NO 1 1 NPS NPS 11428899 11428899 PETN reductase is a monomeric flavoenzyme -- Annotation transfered from 1gvo 1h61 NO 1 1 NPS NPS 11428899 11428899 PETN reductase is a monomeric flavoenzyme -- Annotation transfered from 1gvo 1h62 NO 1 1 NPS NPS 11428899 11428899 PETN reductase is a monomeric flavoenzyme -- Annotation transfered from 1gvo 1h63 NO 1 1 NPS NPS 11428899 11428899 PETN reductase is a monomeric flavoenzyme -- Annotation transfered from 1gvo 1h64_1 NO 7 7 C7 C7 12409299 12409299 Interface conserved with 1n9s (34% id) -- Annotation transfered from 1h64_2 1h64_2 NO 7 7 C7 C7 12409299 12409299 Interface conserved with 1n9s (34% id) 1h64_3 NO 7 7 C7 C7 12409299 12409299 Interface conserved with 1n9s (34% id) -- Annotation transfered from 1h64_2 1h64_4 NO 7 7 C7 C7 12409299 12409299 Interface conserved with 1n9s (34% id) -- Annotation transfered from 1h64_2 1h65_1 NO 2 2 C2 C2 11753431 11753431 BU changed since last release and is now corrected - Paper says weak dimer: however, gel filtration experiments revealed that dimeric and monomeric forms of Toc34 coexisted in phosphate saline buffer solution at pH 7.2. Mutation of Arg 128, an essential residue for dimerization, to an Ala residue led to the formation of an exclusively monomeric species whose GTPase activity is significantly reduced compared to that of wild type Toc34. 1h65_2 NO 2 2 C2 C2 11753431 11753431 BU changed since last release and is now corrected - Paper says weak dimer: however, gel filtration experiments revealed that dimeric and monomeric forms of Toc34 coexisted in phosphate saline buffer solution at pH 7.2. Mutation of Arg 128, an essential residue for dimerization, to an Ala residue led to the formation of an exclusively monomeric species whose GTPase activity is significantly reduced compared to that of wild type Toc34. 1h66_1 NO 2 2 C2 C2 11587640 11587640 BU changed since last release and is now corrected - 1h66_2 NO 2 2 C2 C2 11587640 11587640 BU changed since last release and is now corrected - 1h68 PROBNOT 1 1 NPS NPS 11504917 11504917 No trimeric packing 1h69_1 NO 2 2 C2 C2 11587640 11587640 BU changed since last release and is now corrected - -- Annotation transfered from 1h66 1h69_2 NO 2 2 C2 C2 11587640 11587640 BU changed since last release and is now corrected - -- Annotation transfered from 1h66 1h6a NO 4 4 D2 D2 11705375 11705375 BU changed since last release and is now corrected - Interface geometry conserved with 1tlt (20%) -- Annotation transfered from 1h6b 1h6b NO 4 4 D2 D2 11705375 11705375 BU changed since last release and is now corrected - Interface geometry conserved with 1tlt (20%) 1h6c NO 4 4 D2 D2 11705375 11705375 BU changed since last release and is now corrected - Interface geometry conserved with 1tlt (20%) -- Annotation transfered from 1h6b 1h6d_1 NO 4 4 D2 D2 11705375 11705375 BU changed since last release and is now corrected - Interface geometry conserved with 1tlt (20%) 1h6d_2 NO 4 4 D2 D2 11705375 11705375 BU changed since last release and is now corrected - Interface geometry conserved with 1tlt (20%) 1h6d_3 NO 4 4 D2 D2 11705375 11705375 BU changed since last release and is now corrected - Interface geometry conserved with 1tlt (20%) 1h6h NO 1 1 NPS NPS 11684018 11684018 The analysis yields estimated masses of 34,400 Da and 17,100 Da for the full-length and PX domains, respectively. These masses agree well with the monomeric masses calculated from the sequence 1h6j NO 2 2 C2 C2 8706906 8706906 BU changed since last release and is now corrected - -- PISA error (low resolution) 1h6m NO 1 1 NPS NPS 11518970 11518970 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1h6n YES 1 4 NPS D2 12486720 0 Interface geometry conserved with 1m7s (40% id) -- Annotation transfered from 1e93 1h6r_1 NO 1 1 NPS NPS 11689426 11689426 BU changed since last release and is now corrected - 1h6r_2 NO 1 1 NPS NPS 11689426 11689426 BU changed since last release and is now corrected - 1h6r_3 NO 1 1 NPS NPS 11689426 11689426 BU changed since last release and is now corrected - 1h6s YES 1 3 NPS C3 12468713 0 1h6t PROBNOT 1 1 NPS NPS 11575932 11575932 12526809 shows a monomer 1h6z NO 2 2 C2 C2 12083528 12083528 BU changed since last release and is now corrected - PISA gives the right dimer - interface geometry conserved with 1dik (50%) 1h75 NO 1 1 NPS NPS 11441020 11441020 Monomer version of a domain swapped (1r7h) 1h7e PROBNOT 2 2 C2 C2 11545592 11545592 Paper says dimer : The purified dimeric CKS -- Annotation transfered from 1gq9 1h7f PROBNOT 2 2 C2 C2 11545592 11545592 Paper says dimer : The purified dimeric CKS -- Annotation transfered from 1gq9 1h7g PROBNOT 2 2 C2 C2 11545592 11545592 Paper says dimer : The purified dimeric CKS -- Annotation transfered from 1gq9 1h7h PROBNOT 2 2 C2 C2 11545592 11545592 Paper says dimer : The purified dimeric CKS -- Annotation transfered from 1gq9 1h7k YES 1 4 NPS D2 11695923 0 BU changed since last release and is now incorrect - Interface geometry conserved with 1m7s (40% id) -- Annotation transfered from 1mqf 1h7n NO 8 8 D4 D4 11545591 11545591 BU changed since last release and is now corrected - Paper says octamer -- Annotation transfered from 1h7o 1h7o NO 8 8 D4 D4 11545591 11545591 BU changed since last release and is now corrected - Paper says octamer 1h7p NO 8 8 D4 D4 11545591 11545591 BU changed since last release and is now corrected - Paper says octamer -- Annotation transfered from 1h7o 1h7r NO 8 8 D4 D4 11545591 11545591 BU changed since last release and is now corrected - Paper says octamer -- Annotation transfered from 1h7o 1h7t PROBNOT 2 2 C2 C2 11545592 11545592 Paper says dimer : The purified dimeric CKS -- Annotation transfered from 1gq9 1h7w_1 NO 2 2 C2 C2 11179210 11796730 BU changed since last release and is now corrected - Paper says: The enzyme is a homodimer of 2 × 111 kDa. - automatic transfer from 1gte_2 1h7w_2 NO 2 2 C2 C2 11179210 11796730 BU changed since last release and is now corrected - Paper says: The enzyme is a homodimer of 2 × 111 kDa. - automatic transfer from 1gte_2 1h7x_1 NO 2 2 C2 C2 11179210 11796730 BU changed since last release and is now corrected - Paper says: The enzyme is a homodimer of 2 × 111 kDa. - automatic transfer from 1gte_2 1h7x_2 NO 2 2 C2 C2 11179210 11796730 BU changed since last release and is now corrected - Paper says: The enzyme is a homodimer of 2 × 111 kDa. - automatic transfer from 1gte_2 1h81_1 YES 2 1 C2 NPS 11258887 10368296 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says: PAO is a monomeric soluble protein with a molecular mass of about 53 kDa and a non-covalently bound FAD molecule as cofactor (and gives reference) - automaticaly inferred from 1b5q 1h81_2 YES 2 1 C2 NPS 11258887 10368296 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says: PAO is a monomeric soluble protein with a molecular mass of about 53 kDa and a non-covalently bound FAD molecule as cofactor (and gives reference) - automaticaly inferred from 1b5q 1h82_1 YES 2 1 C2 NPS 11258887 10368296 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says: PAO is a monomeric soluble protein with a molecular mass of about 53 kDa and a non-covalently bound FAD molecule as cofactor (and gives reference) - automaticaly inferred from 1b5q 1h82_2 YES 2 1 C2 NPS 11258887 10368296 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says: PAO is a monomeric soluble protein with a molecular mass of about 53 kDa and a non-covalently bound FAD molecule as cofactor (and gives reference) - automaticaly inferred from 1b5q 1h83_1 YES 2 1 C2 NPS 11258887 10368296 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says: PAO is a monomeric soluble protein with a molecular mass of about 53 kDa and a non-covalently bound FAD molecule as cofactor (and gives reference) - automaticaly inferred from 1b5q 1h83_2 YES 2 1 C2 NPS 11258887 10368296 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says: PAO is a monomeric soluble protein with a molecular mass of about 53 kDa and a non-covalently bound FAD molecule as cofactor (and gives reference) - automaticaly inferred from 1b5q 1h84_1 YES 2 1 C2 NPS 11258887 10368296 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says: PAO is a monomeric soluble protein with a molecular mass of about 53 kDa and a non-covalently bound FAD molecule as cofactor (and gives reference) - automaticaly inferred from 1b5q 1h84_2 YES 2 1 C2 NPS 11258887 10368296 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says: PAO is a monomeric soluble protein with a molecular mass of about 53 kDa and a non-covalently bound FAD molecule as cofactor (and gives reference) - automaticaly inferred from 1b5q 1h85 NO 1 1 NPS NPS 11342548 11342548 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1h86_1 YES 2 1 C2 NPS 11258887 10368296 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says: PAO is a monomeric soluble protein with a molecular mass of about 53 kDa and a non-covalently bound FAD molecule as cofactor (and gives reference) - automaticaly inferred from 1b5q 1h86_2 YES 2 1 C2 NPS 11258887 10368296 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says: PAO is a monomeric soluble protein with a molecular mass of about 53 kDa and a non-covalently bound FAD molecule as cofactor (and gives reference) - automaticaly inferred from 1b5q 1h87 NO 1 1 NPS NPS 11752774 11752774 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1h8f NO 2 2 C2 C2 11440715 11440715 Paper says dimer detected in solution but the functional significance is unclear (autoinhibition is a possibility) - monomer/dimer equilibrium 1h8k PROBNOT 1 1 NPS NPS 12006985 12006985 -- Annotation transfered from 1neg 1h8l PROBNOT 1 1 NPS NPS 11278909 0 1h8n NO 1 1 NPS NPS 11397090 11397090 1h8o_1 NO 1 1 NPS NPS 11397088 11397088 BU changed since last release and is now corrected - Single chain antibody -- Annotation transfered from 1h8s 1h8o_2 NO 1 1 NPS NPS 11397088 11397088 BU changed since last release and is now corrected - Single chain antibody -- Annotation transfered from 1h8s 1h8p NA 4 2 C2 NS 11937055 11937055 BU changed since last release and is now incorrect - 1h8s_1 NO 1 1 NPS NPS 11397088 11397088 BU changed since last release and is now corrected - Single chain antibody 1h8s_2 NO 1 1 NPS NPS 11397088 11397088 BU changed since last release and is now corrected - Single chain antibody 1h8u_1 NA 1 2 NPS C2 11319227 11319227 BU changed since last release and is now incorrect - Paper shows the dimer but no evidence - PISA give another form and to me, both have very weak interfaces. 1h8u_2 NA 1 2 NPS C2 11319227 11319227 BU changed since last release and is now incorrect - Paper shows the dimer but no evidence - PISA give another form and to me, both have very weak interfaces. 1h8v_1 NO 1 1 NPS NPS 11327768 11327768 BU changed since last release and is now corrected - In dynamic light-scattering analysis the protein appears only as a monomer 1h8v_2 NO 1 1 NPS NPS 11327768 11327768 BU changed since last release and is now corrected - In dynamic light-scattering analysis the protein appears only as a monomer 1h8v_3 NO 1 1 NPS NPS 11327768 11327768 BU changed since last release and is now corrected - In dynamic light-scattering analysis the protein appears only as a monomer 1h8v_4 NO 1 1 NPS NPS 11327768 11327768 BU changed since last release and is now corrected - In dynamic light-scattering analysis the protein appears only as a monomer 1h8v_5 NO 1 1 NPS NPS 11327768 11327768 BU changed since last release and is now corrected - In dynamic light-scattering analysis the protein appears only as a monomer 1h8v_6 NO 1 1 NPS NPS 11327768 11327768 BU changed since last release and is now corrected - In dynamic light-scattering analysis the protein appears only as a monomer 1h8x NO 2 2 C2 C2 11591351 11591351 1h8y NO 2 2 C2 C2 11453693 11453693 Paper says dimer - interface geometry conserved with 1k38 (37%) -- Annotation transfered from 1h8z 1h8z NO 2 2 C2 C2 11453693 11453693 Paper says dimer - interface geometry conserved with 1k38 (37%) 1h91 PROBNOT 2 2 C2 C2 11526313 11526313 SP says: Oligomer; Can form dimers (beta-crustacyanin); or complexes of 16 subunits (alpha-crustacyanin). There are five types of subunits: A1, A2, A3, C1 and C2 -- Annotation transfered from 1s2p 1h93 NO 2 2 C2 C2 11320304 11320304 BU changed since last release and is now corrected - identical are dimers and PISA says dimer -- Annotation transfered from 1h9b 1h94 NO 2 2 C2 C2 11320304 11320304 BU changed since last release and is now corrected - identical are dimers and PISA says dimer -- Annotation transfered from 1h9b 1h96 NO 24 24 Octa Octa 11679711 11679711 BU changed since last release and is now corrected - Interface geometry conserved with 1ies (80%) 1h97_1 NO 1 1 NPS NPS 11399085 11399085 BU changed since last release and is now corrected - Paper says: Monomeric hemoglobin from the trematode Paramphistomum epiclitum displays very high oxygen affinity 1h97_2 NO 1 1 NPS NPS 11399085 11399085 BU changed since last release and is now corrected - Paper says: Monomeric hemoglobin from the trematode Paramphistomum epiclitum displays very high oxygen affinity 1h98 PROBNOT 1 1 NPS NPS 11681700 11681700 No access to paper, related proteins are monomeric and PISA says monomer 1h9a NO 2 2 C2 C2 11320304 11320304 BU changed since last release and is now corrected - identical are dimers and PISA says dimer -- Annotation transfered from 1h9b 1h9b NO 2 2 C2 C2 11320304 11320304 BU changed since last release and is now corrected - identical are dimers and PISA says dimer 1h9g PROBNOT 2 2 C2 C2 11296236 11296236 BU changed since last release and is now corrected - 1h9j NO 3 3 C3 C3 11352591 11352591 BU changed since last release and is now corrected - the functional unit of ModG is actually not a dimer (as in ModE), but a trimer -- very interesting case, the only true one from C2 to C3 I know of. 1h9k NO 3 3 C3 C3 11352591 11352591 BU changed since last release and is now corrected - the functional unit of ModG is actually not a dimer (as in ModE), but a trimer -- very interesting case, the only true one from C2 to C3 I know of. -- Annotation transfered from 1h9j 1h9l PROBNOT 1 1 NPS NPS 0 0 -- Annotation transfered from 1c1m 1h9m_1 NO 3 3 C3 C3 11352591 11352591 BU changed since last release and is now corrected - Paper says trimer 1h9m_2 NO 3 3 C3 C3 11352591 11352591 BU changed since last release and is now corrected - Paper says trimer 1h9n PROBNOT 1 1 NPS NPS 9398308 9398308 9000633 says monomeric -- Annotation transfered from 1uga 1h9o NO 1 1 NPS NPS 11567151 11567151 Paper says: Phosphoinositide 3-kinases belonging to this class and which are regulated by growth factor receptor tyrosine kinases, are tightly coupled heterodimers consisting of an 85 kDa regulatory subunit (p85) and a 110 kDa catalytic subunit (p110). So no homo-interaction, plus here only a SH2 domain from the regulatory sub. -- Annotation transfered from 1qad 1h9p YES 4 2 D2 C2 11453695 11453695 BU changed since last release and is now incorrect - Apparently this structure exhibits dimer-tetramer equilibrium 1h9q PROBNOT 1 1 NPS NPS 9398308 9398308 9000633 says monomeric -- Annotation transfered from 1uga 1h9r NO 2 2 C2 C2 11259434 11259434 Paper says dimer 1h9s NO 2 2 C2 C2 11259434 11259434 Paper says dimer - automatic transfer from 1h9r 1h9t NO 2 2 C2 C2 11296236 11296236 -- Annotation transfered from 1e2x 1h9u YES 8 2 D4 C2 11782480 11782480 BU changed since last release and is now incorrect - 1h9v NO 1 1 NPS NPS 11397093 11397093 We showed that FcgRII is monomeric in solution as proven by size exclusion chromatography of both baculo-derived, thus glycosylated, and E. coli material and conclude that the previously observed dimer originates from the requirements of crystal packing. 1h9w PROBNOT 2 2 C2 C2 11453695 11453695 Paper shows a weaker dimer-dimer interface binding. The QS schanges with pH (dimer-tetramer) so it is relevant. 1h9x YES 4 2 C2 C2 11373294 0 BU changed since last release and is now incorrect - Homodimer -- Annotation transfered from 1h9y 1h9y NO 2 2 C2 C2 11373294 10767281 Homodimer 1ha3_1 NO 1 1 NPS NPS 11278992 9838020 BU changed since last release and is now corrected - EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa. 1ha3_2 NO 1 1 NPS NPS 11278992 9838020 BU changed since last release and is now corrected - EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa. 1ha4 NO 2 2 C2 C2 11706012 0 Papers says homodimer and interface conserved to 50% (1gam) - interesting - very interesting also for gene suplication: 1/ each domain is symmetrical 2/ each chain contains two similar domains 3/chains can form homodimers or paralogous dimers! 1ha5_1 PROBYES 1 4 NPS D2 9878045 9878045 BU changed since last release and is now incorrect - Tetramer might be relevant: Structural and mutational studies of SEB, SEC, SPEA, and TSST1 suggest MHC binding uses the sur face on the front of Domain 1.Since this sur face is blocked in the SPEA tetramer, tetramer–monomer equilibrium will likely modulate superantigenicity. The ability of factors to stabilize the tetramer could be employed to reduce the ability of SPEA to stimulate T-cell proliferation. 1ha5_2 PROBYES 1 4 NPS D2 9878045 9878045 BU changed since last release and is now incorrect - Tetramer might be relevant: Structural and mutational studies of SEB, SEC, SPEA, and TSST1 suggest MHC binding uses the sur face on the front of Domain 1.Since this sur face is blocked in the SPEA tetramer, tetramer–monomer equilibrium will likely modulate superantigenicity. The ability of factors to stabilize the tetramer could be employed to reduce the ability of SPEA to stimulate T-cell proliferation. 1ha5_3 PROBYES 1 4 NPS D2 9878045 9878045 BU changed since last release and is now incorrect - Tetramer might be relevant: Structural and mutational studies of SEB, SEC, SPEA, and TSST1 suggest MHC binding uses the sur face on the front of Domain 1.Since this sur face is blocked in the SPEA tetramer, tetramer–monomer equilibrium will likely modulate superantigenicity. The ability of factors to stabilize the tetramer could be employed to reduce the ability of SPEA to stimulate T-cell proliferation. 1ha5_4 PROBYES 1 4 NPS D2 9878045 9878045 BU changed since last release and is now incorrect - Tetramer might be relevant: Structural and mutational studies of SEB, SEC, SPEA, and TSST1 suggest MHC binding uses the sur face on the front of Domain 1.Since this sur face is blocked in the SPEA tetramer, tetramer–monomer equilibrium will likely modulate superantigenicity. The ability of factors to stabilize the tetramer could be employed to reduce the ability of SPEA to stimulate T-cell proliferation. 1hag PROBNOT 1 1 NPS NPS 7756983 7756983 -- Annotation transfered from 1doj 1hak YES 2 1 C2 NPS 9398511 9398511 SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) - So no dimer 1han NO 8 8 D4 D4 7481800 7481800 Interface geometry conserved with 1kw6 (66%) -- Annotation transfered from 1knf 1har PROBNOT 1 1 NPS NPS 7532533 7532533 The reverse transcriptase is a heterodimer of p66 RT and p51 RT (RT p66/p51). Heterodimerization of RT is essential for DNA polymerase activity. 1hau NO 3 3 C3 C3 11468394 11468394 BU changed since last release and is now corrected - -- Annotation transfered from 1haw 1haw NO 3 3 C3 C3 11468394 11468394 BU changed since last release and is now corrected - 1hax PROBNOT 1 1 NPS NPS 11473259 0 -- Annotation transfered from 1c1m 1hay PROBNOT 1 1 NPS NPS 11473259 0 -- Annotation transfered from 1c1m 1haz PROBNOT 1 1 NPS NPS 11473259 11473259 -- Annotation transfered from 1c1m 1hb0 PROBNOT 1 1 NPS NPS 11473259 0 -- Annotation transfered from 1c1m 1hb1 PROBNOT 1 1 NPS NPS 11755401 11755401 No info was found, PISA says monomer. I also think it should be. -- Annotation transfered from 1uzw 1hb2 PROBNOT 1 1 NPS NPS 11755401 11755401 No info was found, PISA says monomer. I also think it should be. -- Annotation transfered from 1uzw 1hb3 PROBNOT 1 1 NPS NPS 11755401 11755401 No info was found, PISA says monomer. I also think it should be. -- Annotation transfered from 1uzw 1hb4 PROBNOT 1 1 NPS NPS 11755401 11755401 No info was found, PISA says monomer. I also think it should be. -- Annotation transfered from 1uzw 1hbg PROBNOT 1 1 NPS NPS 2585515 2585515 SP says monomer -- Annotation transfered from 2hbg 1hbi NO 2 2 C2 C2 7929217 7929217 Paper and SP say dimer -- Annotation transfered from 7hbi 1hbj PROBYES 2 1 C2 NPS 11563919 11563919 BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1hbp NO 1 1 NPS NPS 8496140 8496140 Circulating in the plasma, the monomeric RBP molecule (21 kDa) is found associated in a macromolecular complex with the tetrameric thyroxine-binding transthyretin (55 kDa). The formation of the RBP–transthyretin complex is believed to prevent filtration through renal glomeruli of the relatively small RBP molecule. -- Annotation transfered from 1kt5 1hbq NO 1 1 NPS NPS 8496140 8496140 Circulating in the plasma, the monomeric RBP molecule (21 kDa) is found associated in a macromolecular complex with the tetrameric thyroxine-binding transthyretin (55 kDa). The formation of the RBP–transthyretin complex is believed to prevent filtration through renal glomeruli of the relatively small RBP molecule. -- Annotation transfered from 1kt5 1hbv NO 2 2 C2 C2 7650677 7650677 -- Annotation transfered from 1ajx 1hby NO 1 1 NPS NPS 11468363 11468363 Human angiogenin is monomeric -- Annotation transfered from 1h52 1hbz NO 4 4 D2 D2 1426241 1426241 BU changed since last release and is now corrected - Interface geometry conserved with 1mqf (50% id) -- Annotation transfered from 1gwh 1hc0 PROBYES 10 1 NR NPS 16131750 1185784 BU changed since last release and is now incorrect - Lysozyme C is well established as being monomeric - automaticaly inferred from 8lyz 1hc1 YES 1 3 NPS D3 2585484 2585484 Paper says hexamer 1hc2 YES 1 3 NPS D3 2585484 2585484 Paper says hexamer -- Annotation transfered from 1hc1 1hc3 YES 1 3 NPS D3 2585484 2585484 Paper says hexamer -- Annotation transfered from 1hc1 1hc4 YES 1 3 NPS D3 2585484 2585484 Paper says hexamer -- Annotation transfered from 1hc1 1hc5 YES 1 3 NPS D3 2585484 2585484 Paper says hexamer -- Annotation transfered from 1hc1 1hc6 YES 1 3 NPS D3 2585484 2585484 Paper says hexamer -- Annotation transfered from 1hc1 1hca PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1hcb NO 1 1 NPS NPS 8057362 8057362 10529183 says monomer -- Annotation transfered from 1crm 1hcg PROBNOT 2 2 NPS NPS 8355279 8355279 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1hch PROBNOT 1 1 NPS NPS 12024218 12024218 SP says monomer -- Annotation transfered from 7atj 1hcj_1 YES 4 1 D2 NPS 11740505 11740505 BU changed since last release and is now incorrect - 1hcj_2 YES 4 1 D2 NPS 11740505 11740505 BU changed since last release and is now incorrect - 1hck NO 1 1 NPS NPS 8917641 8917641 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1hcl NO 1 1 NPS NPS 7479711 7479711 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1hcm NO 2 2 C2 C2 11373294 0 Homodimer -- Annotation transfered from 1h9y 1hcu_1 PROBNOT 1 1 NPS NPS 11545593 11545593 BU changed since last release and is now corrected - Paper does not mention an oligomer -- PISA says monomer 1hcu_2 PROBNOT 1 1 NPS NPS 11545593 11545593 BU changed since last release and is now corrected - Paper does not mention an oligomer -- PISA says monomer 1hcu_3 PROBNOT 1 1 NPS NPS 11545593 11545593 BU changed since last release and is now corrected - Paper does not mention an oligomer -- PISA says monomer 1hcu_4 PROBNOT 1 1 NPS NPS 11545593 11545593 BU changed since last release and is now corrected - Paper does not mention an oligomer -- PISA says monomer 1hcv NO 1 1 NPS NPS 8784347 10684599 Paper says monomeric 1hcy NO 6 6 D3 D3 2585484 2585484 BU changed since last release and is now corrected - Paper says hexamer 1hd2 NO 1 1 NPS NPS 11518528 11518528 Paper says: PRDX5 is characterized by a molecular mass of 17 kDa and exists as a single-domain monomeric protein. -- Very interesting, same family and Monomer, Dimer, Decamer, different interfaces and high conservation! Good for evolution too 1hd3 PROBNOT 1 1 NPS NPS 11959988 11959988 -- Annotation transfered from 1neg 1hdc NO 4 4 D2 D2 7866748 7866748 SP says homotetramer 1hde_1 NO 1 1 NPS NPS 8855957 8369276 SP says monomer - automatic transfer from 1edb 1hde_2 NO 1 1 NPS NPS 8855957 8369276 SP says monomer - automatic transfer from 1edb 1hdh YES 2 1 C2 NPS 11435113 11435113 Although the asymmetric unit contains two molecules, the contacts found in the crystal structure among both monomers do not persist in solution, as the apparent molecular weight determined by gel filtration is 39 kDa, which is compatible with a monomeric structure. Plus the potential dimeric contact is not conserved with 1n2k. 1hdk NO 1 1 NPS NPS 11834744 0 Forms crystals in vivo! -- Annotation transfered from 1g86 1hdo NO 1 1 NPS NPS 11224564 11224564 Paper says monomer 1hdx NO 2 2 C2 C2 8201622 8201622 Dimer of identical or non-identical chains of three types - gene dup - interesting 1hdy NO 2 2 C2 C2 8201622 8201622 Dimer of identical or non-identical chains of three types - gene dup - interesting -- Annotation transfered from 1hdx 1hdz NO 2 2 C2 C2 8201622 8201622 Dimer of identical or non-identical chains of three types - gene dup - interesting -- Annotation transfered from 1hdx 1he2 NO 1 1 NPS NPS 11224564 11224564 Paper says monomer -- Annotation transfered from 1hdo 1he3 NO 1 1 NPS NPS 11224564 11224564 Paper says monomer -- Annotation transfered from 1hdo 1he4 NO 1 1 NPS NPS 11224564 11224564 Paper says monomer -- Annotation transfered from 1hdo 1he5 NO 1 1 NPS NPS 11224564 11224564 Paper says monomer -- Annotation transfered from 1hdo 1he8 PROBNOT 2 2 NPS NPS 11136978 16483931 Paper points to this structure as being biological -- Annotation transfered from 2c5l_1 1hea PROBNOT 1 1 NPS NPS 8485129 0 9000633 says monomeric -- Annotation transfered from 1uga 1heb PROBNOT 1 1 NPS NPS 8485129 8485129 9000633 says monomeric -- Annotation transfered from 1uga 1hec PROBNOT 1 1 NPS NPS 8485129 8485129 9000633 says monomeric -- Annotation transfered from 1uga 1hed PROBNOT 1 1 NPS NPS 8485129 8485129 9000633 says monomeric -- Annotation transfered from 1uga 1hef NO 2 2 C2 C2 1429626 1429626 -- Annotation transfered from 1ajx 1heg NO 2 2 C2 C2 1429626 1429626 -- Annotation transfered from 1ajx 1hei PROBNOT 2 2 C2 C2 9187654 9614113 Although Rep DNA helicase, for example, is a stable monomer in solution in the absence of DNA, a dimeric form of Rep is induced in the presence of DNA which is known as the functional form. So this dimer could be relevant (PISA says so) - note however, that another dimeric form is found in 8ohm, which PISA doesnt believe but might be worth checking. 1hek_1 NA 1 2 NPS NS 11799182 11799182 BU changed since last release and is now incorrect - The same authors observe that EIAV MA exists as a multimer in solution whose protein-protein interactions are destabilized by membrane binding. They suggest that the protein can form dimers, possibly related to the intermolecular contacts found in our crystal. 1hek_2 NA 1 2 NPS NS 11799182 11799182 BU changed since last release and is now incorrect - The same authors observe that EIAV MA exists as a multimer in solution whose protein-protein interactions are destabilized by membrane binding. They suggest that the protein can form dimers, possibly related to the intermolecular contacts found in our crystal. 1hel NO 1 1 NPS NPS 1587860 1587860 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1hem NO 1 1 NPS NPS 1587860 1587860 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1hen NO 1 1 NPS NPS 1587860 1587860 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1heo NO 1 1 NPS NPS 1587860 1587860 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1hep NO 1 1 NPS NPS 1587860 1587860 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1heq NO 1 1 NPS NPS 1587860 1587860 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1her NO 1 1 NPS NPS 1587860 1587860 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1het NO 2 2 C2 C2 11134046 11134046 -- Annotation transfered from 8adh 1heu NO 2 2 C2 C2 11134046 11134046 -- Annotation transfered from 8adh 1hew NO 1 1 NPS NPS 1569548 1569548 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1hf0 NO 2 2 C2 C2 11583619 11583619 Paper says homodimer - Very interesting protein, induced dimerization (phosphate), different conformations at 100% id (DNA induced) - PISA right 1hf2_1 NO 2 2 C2 C2 11350934 11350934 BU changed since last release and is now corrected - Paper says dimer: The protein eluted as a single peak with a retention time suggesting a dimer. The dimer is very stable, even in buffers containing 4 M NaCl (data not shown). 1hf2_2 YES 2 2 NS C2 11350934 11350934 BU changed since last release and is now incorrect - Paper says dimer: The protein eluted as a single peak with a retention time suggesting a dimer. The dimer is very stable, even in buffers containing 4 M NaCl (data not shown). 1hf3 NO 2 2 C2 C2 11134046 11134046 -- Annotation transfered from 8adh 1hf4_1 NO 1 1 NPS NPS 11418760 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1hf4_2 NO 1 1 NPS NPS 11418760 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1hf8 PROBYES 2 1 C2 NPS 11161218 11190274 BU changed since last release and is now incorrect - 1hfa PROBYES 2 1 C2 NPS 11161218 11161218 BU changed since last release and is now incorrect - -- Annotation transfered from 1hf8 1hfb YES 8 4 C2 D2 12540830 0 cf. 1oab 1hfc PROBNOT 1 1 NPS NPS 8090713 8090713 No clear evidence after a quick search but PISA agrees ... 1hfd PROBNOT 1 1 NPS NPS 9753554 9753554 -- Annotation transfered from 1dic 1hfp PROBNOT 1 1 NPS NPS 9627670 9627670 -- Annotation transfered from 1s3u 1hfq PROBNOT 1 1 NPS NPS 9627670 9627670 -- Annotation transfered from 1s3u 1hfr PROBNOT 1 1 NPS NPS 9627670 9627670 -- Annotation transfered from 1s3u 1hfs PROBYES 2 1 C2 NPS 9083493 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme 1hfu PROBNOT 1 1 NPS NPS 11173497 11173497 Paper says: C. cinereus laccase is a monomeric molecule consisting of three tightly associated cupredoxin-like domains 1hfy YES 2 1 C2 NPS 8805552 8805552 Lactose synthase (LS) is a heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA). 1hg2 PROBYES 2 1 C2 NPS 11161218 11161218 BU changed since last release and is now incorrect - -- Annotation transfered from 1hf8 1hg5 PROBYES 2 1 C2 NPS 11161218 11190274 1hgu PROBNOT 1 1 NPS NPS -1 0 SP says: Monomer, dimer, trimer, tetramer and pentamer, disulfide-linked or non-covalently associated, in homopolymeric and heteropolymeric combinations. Can also form a complex either with GHBP or with the alpha2-macroglobulin complex -- family remark: again, good example to show that secreted proteins are not well defined and very versatile in terms of their oligomeric states. 1hgw_1 PROBNOT 1 1 NPS NPS 12188666 12188666 BU changed since last release and is now corrected - Paper implies monomer - PISA also says monomer 1hgw_2 PROBNOT 1 1 NPS NPS 12188666 12188666 BU changed since last release and is now corrected - Paper implies monomer - PISA also says monomer 1hgx NO 2 2 C2 C2 8679528 8679528 Monomer dimer equilibrium or ligand induced dimerization? - paper says: More importantly, the spatial arrangement of the two monomers is very similar to the relation between the monomers that form the dimer seen in the structure of human HGPRTase (Figure 8a), which is known to function as either a dimer or tetramer, depending on the pH and ionic strength of the solution (Johnson et al., 1979). The existence of the dimer was somewhat surprising in light of the work of Beck and Wang (1993) and Chin (1995), who studied the oligomerization state of T. foetus HGXPRTase using gel filtration chromatography and native gel electrophoresis. Under the conditions used in those studies, which did not include ligand, HGXPRTase was present primarily as a monomer, although a small percentage of the protein did form dimers. -- interesting 1hgy_1 PROBNOT 1 1 NPS NPS 12188666 0 BU changed since last release and is now corrected - Paper implies monomer - PISA also says monomer -- Annotation transfered from 1hgw 1hgy_2 PROBNOT 1 1 NPS NPS 12188666 0 BU changed since last release and is now corrected - Paper implies monomer - PISA also says monomer -- Annotation transfered from 1hgw 1hh5 NA 1 2 NPS C2 11320307 11320307 Paper suggest dimeric interaction is relevant but PISA doent find it and me neither 1hh7 PROBNOT 1 1 NPS NPS 11092951 11092951 1hhl NO 1 1 NPS NPS 8061608 8061608 1hhp NO 2 2 C2 C2 1799632 1799632 -- Annotation transfered from 1ajx 1hhq NO 6 6 D3 D3 11277918 11277918 BU changed since last release and is now corrected - Paper says hexamer 1hhs_1 PROBNOT 1 1 NPS NPS 11242087 11242087 BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands 1hhs_2 PROBNOT 1 1 NPS NPS 11242087 11242087 BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands 1hhs_3 PROBNOT 1 1 NPS NPS 11242087 11242087 BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands 1hht_1 PROBNOT 1 1 NPS NPS 11242087 11242087 BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands - automatic transfer from 1hhs_3 1hht_2 PROBNOT 1 1 NPS NPS 11242087 11242087 BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands - automatic transfer from 1hhs_3 1hht_3 PROBNOT 1 1 NPS NPS 11242087 11242087 BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands - automatic transfer from 1hhs_3 1hi0_1 PROBNOT 1 1 NPS NPS 11242087 11242087 BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands - automatic transfer from 1hhs_3 1hi0_2 PROBNOT 1 1 NPS NPS 11242087 11242087 BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands - automatic transfer from 1hhs_3 1hi0_3 PROBNOT 1 1 NPS NPS 11242087 11242087 BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands - automatic transfer from 1hhs_3 1hi1_1 PROBNOT 1 1 NPS NPS 11242087 11242087 BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands -- Annotation transfered from 1hhs 1hi1_2 PROBNOT 1 1 NPS NPS 11242087 11242087 BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands -- Annotation transfered from 1hhs 1hi1_3 PROBNOT 1 1 NPS NPS 11242087 11242087 BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands -- Annotation transfered from 1hhs 1hi2 PROBNOT 1 1 NPS NPS 11154698 11154698 1hi3 PROBNOT 1 1 NPS NPS 11154698 11154698 -- Annotation transfered from 1hi2 1hi4 PROBNOT 1 1 NPS NPS 11154698 11154698 -- Annotation transfered from 1hi2 1hi5 PROBNOT 1 1 NPS NPS 11154698 11154698 -- Annotation transfered from 1hi2 1hi8_1 NO 1 1 NPS NPS 11242087 11242087 BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands 1hi8_2 NO 1 1 NPS NPS 11242087 11242087 BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands 1hi9 NO 10 10 D5 D5 11473256 11473256 BU changed since last release and is now corrected - Paper says decamer with 522 symmetry. 1hib PROBNOT 1 1 NPS NPS 8364024 8364024 SP says monomer -- Annotation transfered from 21bi 1hig NA 4 2 D2 C2 1902591 1902591 BU changed since last release and is now incorrect - Domain swapped dimer but only the backbone is defined --> problem with PISA 1hih NO 2 2 C2 C2 7613867 7613867 -- Annotation transfered from 1ajx 1hii NO 2 2 C2 C2 7613867 7613867 1hij PROBYES 2 1 C2 NPS 7707380 7707380 In a cell paper, binds receptor as a monomer (10219247)- in a JBC paper, purified as a monomer (7706290) - PISA says monomer 1hik PROBYES 2 1 C2 NPS 7707380 7707380 In a cell paper, binds receptor as a monomer (10219247)- in a JBC paper, purified as a monomer (7706290) - PISA says monomer -- Annotation transfered from 1hij 1hip PROBNOT 1 1 NPS NPS 4855287 4855287 The protein seem to be in a monomer dimer equilibrium (12077426 EPR and NMR studies have shown that HiPIPs might dimerize in the solution through their hydrophobic surfaces, a discovery that has led to important insights regarding the electron-transfer pathway) -- Annotation transfered from 1b0y 1hiv NO 2 2 C2 C2 1304383 1304383 -- Annotation transfered from 1ajx 1hix PROBYES 2 1 NS NPS 11717493 11717493 BU changed since last release and is now incorrect - 1hiy PROBNOT 6 6 D3 D3 11294625 11294625 BU changed since last release and is now corrected - 1hj1 PROBNOT 2 2 C2 C2 11250199 11250199 BU changed since last release and is now corrected - 1hj3 NO 2 2 C2 C2 11278884 0 Homodimer -- Annotation transfered from 1h9y 1hj4 NO 2 2 C2 C2 11278884 0 Homodimer -- Annotation transfered from 1h9y 1hj5 NO 2 2 C2 C2 11278884 0 Homodimer -- Annotation transfered from 1h9y 1hj8 PROBNOT 1 1 NPS NPS 11264577 11264577 -- Annotation transfered from 1utm 1hj9 PROBNOT 1 1 NPS NPS 11264577 11264577 -- Annotation transfered from 1az8 1hjf PROBYES 3 1 C3 NPS 11279000 9723623 BU changed since last release and is now incorrect - this suggests that the trimeric structure of the apoenzyme found in the crystal might have some functional significance, for example in the protection of the C-terminal arm (rich in lysines and arginines) against proteases in the apo- or resting forms of DAOCS. However, DAOCS dissociates into monomers in the presence of Fe(II) and 2-oxoglutarate. 1hjg PROBYES 3 1 C3 NPS 11279000 11279000 BU changed since last release and is now incorrect - this suggests that the trimeric structure of the apoenzyme found in the crystal might have some functional significance, for example in the protection of the C-terminal arm (rich in lysines and arginines) against proteases in the apo- or resting forms of DAOCS. However, DAOCS dissociates into monomers in the presence of Fe(II) and 2-oxoglutarate. -- Annotation transfered from 1hjf 1hjj PROBNOT 1 1 NPS NPS 0 0 Paper says : The MobA protein has been isolated previously, and it has proved to be monomeric in solution. - Other papers says equilibrium -- Annotation transfered from 1e5k 1hjl PROBNOT 1 1 NPS NPS 0 0 Paper says : The MobA protein has been isolated previously, and it has proved to be monomeric in solution. - Other papers says equilibrium -- Annotation transfered from 1e5k 1hjp NO 4 4 C4 C4 9493263 9493263 Paper says tetramer 1hjt NO 1 1 NPS NPS 9533619 9533619 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1hjv PROBYES 4 1 D2 NPS 0 0 Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. -- Annotation transfered from 1hjx 1hjw PROBYES 2 1 C2 NPS 0 12775711 BU changed since last release and is now incorrect - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1hjx PROBYES 4 1 D2 NPS 0 12775711 Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. 1hk0 PROBNOT 1 1 NPS NPS 12729747 0 y-Crystallins are exclusively monomeric -- Annotation transfered from 1h4a 1hk9 NO 6 6 C6 C6 12853626 12853626 Paper says homohexamer 1hka PROBNOT 1 1 NPS NPS 10378268 10378268 EcoCyc & SP say monomer. -- Annotation transfered from 1eqm 1hkb_1 PROBNOT 1 1 NPS NPS 9493266 10686099 SP says monomer - automatic transfer from 1dgk 1hkb_2 PROBNOT 1 1 NPS NPS 9493266 10686099 SP says monomer - automatic transfer from 1dgk 1hkc PROBYES 2 1 C2 NPS 9735292 9735292 SP says monomer 1hki NO 1 1 NPS NPS 12639956 12639956 Monomer: paper says: the enzyme occurs in two major forms of 39 and 50 kDa. The subsequent cloning of its cDNA from a macrophage library showed that the 50-kDa form can be converted to the 39-kDa form post-translationally or by RNA processing 1hkj NO 1 1 NPS NPS 12639956 0 Monomer: paper says: the enzyme occurs in two major forms of 39 and 50 kDa. The subsequent cloning of its cDNA from a macrophage library showed that the 50-kDa form can be converted to the 39-kDa form post-translationally or by RNA processing -- Annotation transfered from 1hki 1hkk NO 1 1 NPS NPS 12639956 0 Monomer: paper says: the enzyme occurs in two major forms of 39 and 50 kDa. The subsequent cloning of its cDNA from a macrophage library showed that the 50-kDa form can be converted to the 39-kDa form post-translationally or by RNA processing -- Annotation transfered from 1hki 1hkm NO 1 1 NPS NPS 12639956 0 Monomer: paper says: the enzyme occurs in two major forms of 39 and 50 kDa. The subsequent cloning of its cDNA from a macrophage library showed that the 50-kDa form can be converted to the 39-kDa form post-translationally or by RNA processing -- Annotation transfered from 1hki 1hkn PROBYES 6 1 NS NPS 12676958 8652550 BU changed since last release and is now incorrect - SP says monomer - automaticaly inferred from 2afg 1hkp PROBNOT 1 1 NPS NPS 0 14764581 Paper says nothing, PISA says monomer - automatic transfer from 1hl0 1hku YES 1 1 NPS NPS 12805226 0 Interface conserved with 2nac (31%) 1hkz PROBNOT 1 1 NPS NPS 14764581 0 Paper says nothing, PISA says monomer -- Annotation transfered from 1hl0 1hl0 PROBNOT 1 1 NPS NPS 0 14764581 Paper says nothing, PISA says monomer 1hl1 PROBNOT 1 1 NPS NPS 0 0 Paper says nothing, PISA says monomer -- Annotation transfered from 1hl0 1hl2 NO 4 4 D2 D2 12711733 0 Interface geometry conserved with 1s5w (25%) -- Annotation transfered from 1fdy 1hl3 YES 1 1 NPS NPS 12805226 0 Interface conserved with 2nac (31%) -- Annotation transfered from 1hku 1hl4 YES 4 2 D2 C2 12729761 12441104 Paper and SP say dimer 1hl5 YES 18 2 NS C2 12729761 12441104 Mammalian Cu,Zn SOD assembles into an unusually stable homodimer 1hlb NO 1 1 NPS NPS 7650740 7650740 Paper says: We present here a structural analysis of two hemoglobins from C. arenicola; a monomeric, hemichrome Hb-C chain (THIS ONE), and a dimeric, cyanomet Hb-D chain. Attempts to obtain deoxy-, liganded, and hemichrome forms of a single-chain type have not been successful; however, the C and D chains share 65% sequence identit~ and it is known that C2, D2 and CD dimers exist, and that all of these convert to a monomeric state upon hemichrome formation (Bonaventura & Kitto, 1973). 1hlc NO 2 2 C2 C2 8262940 8262940 Paper says dimer 1hld NO 2 2 C2 C2 8172897 8172897 -- Annotation transfered from 8adh 1hlf NO 2 2 C2 C2 11741774 11741774 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1hlk_1 PROBNOT 1 1 NPS NPS 12019104 9730812 BU changed since last release and is now corrected - - automaticaly inferred from 1a7t 1hlk_2 PROBNOT 1 1 NPS NPS 12019104 9730812 BU changed since last release and is now corrected - - automaticaly inferred from 1a7t 1hlm NO 2 2 C2 C2 2049384 2049384 7650740 says: We present here a structural analysis of two hemoglobins from C. arenicola; a monomeric, hemichrome Hb-C chain, and a dimeric, cyanomet Hb-D chain (THIS ONE). Attempts to obtain deoxy-, liganded, and hemichrome forms of a single-chain type have not been successful; however, the C and D chains share 65% sequence identit~ and it is known that C2, D2 and CD dimers exist, and that all of these convert to a monomeric state upon hemichrome formation (Bonaventura & Kitto, 1973). 1hlp PROBYES 2 4 C2 D2 -1 0 SP says tetramer -- strange PISA says dimer - error? 1hlq PROBYES 3 1 NS NPS 12925788 12925788 Paper says: Although three monomers were found in the asymmetric unit, there is no evidence that the trimer corresponds to the organization of the active molecule in vivo. It is more likely to be an artefact of the crystal packing. 1hlw NO 6 6 D3 D3 11148034 11148034 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1hlz NO 2 2 NS NS 11669620 11669620 Binds direct DNA repeats 1hm5 NO 2 2 C2 C2 12368100 12368100 -- Annotation transfered from 1iat 1hmk YES 2 1 NS NPS 9887272 9887272 Lactose synthase (LS) is a heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA). 1hml PROBNOT 1 1 NPS NPS 8366079 8366079 SP says: Lactose synthase (LS) is a heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA). -- Annotation transfered from 1b9o 1hmp NO 4 4 D2 D2 8044844 8044844 Tetramer, interface conserved down to 40% (1fsg). -- Annotation transfered from 1bzy 1hmr PROBNOT 1 1 NPS NPS 7922029 7922029 No info found but PISA says monomer and homologous proteins are monomeric so I will assume it is one. 1hms PROBNOT 1 1 NPS NPS 7922029 7922029 No info found but PISA says monomer and homologous proteins are monomeric so I will assume it is one. -- Annotation transfered from 1hmr 1hmt PROBNOT 1 1 NPS NPS 7922029 7922029 No info found but PISA says monomer and homologous proteins are monomeric so I will assume it is one. -- Annotation transfered from 1hmr 1hn2 NO 2 2 C2 C2 11114310 11114310 Domain Swapped dimer -- Annotation transfered from 1gt1 1hn4 PROBNOT 2 2 C2 C2 11560489 11560489 Papers of identical structures speak about the dimer as something relevant but it is interesting to note that two modes of dimerization exist among these proteins. I have not seen this discussed -- Annotation transfered from 1fx9 1hn9 NO 2 2 C2 C2 10593943 10593943 -- Annotation transfered from 1hnj 1hna NO 2 2 C2 C2 8182750 8182750 1hnb NO 2 2 C2 C2 8182750 8182750 -- Annotation transfered from 1hna 1hnc_1 NO 2 2 C2 C2 8182750 8182750 - automatic transfer from 1hna 1hnc_2 NO 2 2 C2 C2 8182750 8182750 - automatic transfer from 1hna 1hnd NO 2 2 C2 C2 11243824 11243824 -- Annotation transfered from 1hnj 1hne PROBYES 3 1 C3 NPS 2911584 2911584 Neutrophil elastase is a monomeric glycoprotein -- Annotation transfered from 1ppg 1hng NA 2 1 NS NPS 1279440 1279440 1hnh NO 2 2 C2 C2 11243824 11243824 -- Annotation transfered from 1hnj 1hnj NO 2 2 C2 C2 11243824 11243824 1hnk NO 2 2 C2 C2 11243824 11243824 -- Annotation transfered from 1hnj 1hnl NO 1 1 NPS NPS 15299791 0 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1hno PROBNOT 6 6 D3 D3 11399063 11399063 The variable mode of assembly of the trimeric disks of the crotonase superfamily - interesting - the hexamer is very loose (compared to 1k39) but the paper seems to say that it is physiologicaly relevant. 1hnu PROBNOT 6 6 D3 D3 11399063 11399063 The variable mode of assembly of the trimeric disks of the crotonase superfamily - interesting - the hexamer is very loose (compared to 1k39) but the paper seems to say that it is physiologicaly relevant. 1hor NO 6 6 D3 D3 8747459 8747459 SP and EcoCyc say hexamer. -- Annotation transfered from 1cd5 1hos NO 2 2 C2 C2 8347601 8347601 -- Annotation transfered from 1ajx 1hot NO 6 6 D3 D3 8747459 8747459 SP and EcoCyc say hexamer. -- Annotation transfered from 1cd5 1hox NO 2 2 C2 C2 11425306 11425306 -- Annotation transfered from 1iat 1hoz NO 2 2 C2 C2 11292348 11292348 Paper says dimer: The T. vivax IAG-NH is a homodimer, with each subunit consisting of ten beta-strands, 12 alpha-helices and three small 3(10)-helices. - We estimated the apparent molecular mass of the active nucleoside hydrolase from T. vivax using gel chromatography on a 10/30 Superdex-200 HR column. The enzyme elutes with a distribution coefficient (Kd in equation (1)) of 0.42 corresponding to a calculated molecular mass of 59,600 Da. Denaturing polyacrylamide gel electrophoresis gave a single band with a subunit molecular mass of approximately 35,000 Da, consistent with the predicted subunit molecular mass of 37,584 Da. 1hp0 NO 2 2 C2 C2 11292348 11292348 Paper says dimer: The T. vivax IAG-NH is a homodimer, with each subunit consisting of ten beta-strands, 12 alpha-helices and three small 3(10)-helices. - We estimated the apparent molecular mass of the active nucleoside hydrolase from T. vivax using gel chromatography on a 10/30 Superdex-200 HR column. The enzyme elutes with a distribution coefficient (Kd in equation (1)) of 0.42 corresponding to a calculated molecular mass of 59,600 Da. Denaturing polyacrylamide gel electrophoresis gave a single band with a subunit molecular mass of approximately 35,000 Da, consistent with the predicted subunit molecular mass of 37,584 Da. -- Annotation transfered from 1hoz 1hp7 PROBNOT 1 1 NPS NPS 11178897 11178897 Paper says nothing, forms a heterodimer with an apparent 1:1 ratio (1oph) and PISA says monomer -- Annotation transfered from 1oo8 1hpb PROBNOT 1 1 NPS NPS 8307974 8307974 Paper doesn not mention a dimer, monomeric homologs and PISA says monomer 1hpc PROBYES 2 1 C2 NPS 15299773 0 They do not speak about dimers and an experiment in the paper suggests that it is a monomer. -- Annotation transfered from 1dxm 1hpi NA 1 1 NPS NPS 8117708 8117708 PISA says monomer - SP says dimer - an email was sent to the authors 1hpo NO 2 2 C2 C2 9089336 9089336 -- Annotation transfered from 1ajx 1hps NO 2 2 C2 C2 7932533 7932533 -- Annotation transfered from 1ajx 1hpv NO 2 2 C2 C2 -1 0 -- Annotation transfered from 1ajx 1hpx NO 2 2 C2 C2 8590019 8590019 -- Annotation transfered from 1ajx 1hq2 PROBNOT 1 1 NPS NPS 12578370 12578370 EcoCyc & SP say monomer. -- Annotation transfered from 1eqm 1hq5_1 NO 3 3 C3 C3 11258879 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automatic transfer from 1hqx 1hq5_2 NO 3 3 C3 C3 11258879 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automatic transfer from 1hqx 1hq8 NO 2 2 C2 C2 11224525 11224525 Paper says dimer -- interessting: symmetric molecule and asymmetric binding partner. 1hqd PROBNOT 1 1 NPS NPS 11453990 11453990 SP says monomer, PISA too -- Annotation transfered from 5lip 1hqf NO 3 3 C3 C3 11258880 11258880 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference -- Annotation transfered from 1hqx 1hqg NO 3 3 C3 C3 11258880 11258880 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference -- Annotation transfered from 1hqx 1hqh NO 3 3 C3 C3 11258880 11258880 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference -- Annotation transfered from 1hqx 1hql NO 4 4 D2 D2 11714721 11714721 Paper says tetramer 1hqo NO 2 2 C2 C2 11171973 11171973 Interface geometry conserved with 1e6b (26%) 1hqp NO 1 1 NPS NPS 11119644 11119644 Porcine OBP was believed for a long time to be a monomer under physiological conditions but there are recent data that support the existence of a monomer-dimer equilibrium. 1hqq NO 4 4 D2 D2 0 0 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1hqt NO 1 1 NPS NPS 11306083 11306083 Swissprot and PISA say monomer -- Annotation transfered from 1cwn 1hqv NO 2 2 C2 C2 11525164 11525164 Lo et al. [25] showed recently that at 25 μM concentration ALG-2 forms both monomers and dimers in vitro. Further investigations by the two-hybrid method showed the presence of dimers in vivo [19 and 20]. Our dynamic light scattering measurements under conditions close to those used for crystallization (2 mg/ml concentration) show only the presence of dimers. - monomer dimer equilibrium 1hqw NO 4 4 D2 D2 11330349 11330349 SP says tetramer -- Annotation transfered from 1cjp 1hqx NO 3 3 C3 C3 11278703 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference 1hqy_3 NO 6 6 C6 C6 11709174 10693812 HSLU is the outer ring so it forms a hexamer (not a dodecamer) - automatic transfer from 1do0 1hrc PROBNOT 1 1 NPS NPS 2166170 2166170 1hrh PROBYES 2 1 C2 NPS 1707186 1707186 123 aa of a >1400 aa protein. This contact is probably an artifact. 1hrm NO 1 1 NPS NPS 7849057 7849057 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1hrn PROBYES 2 1 NS NPS 7608971 7608971 -- Annotation transfered from 1bim 1hrs NO 24 24 Octa Octa 15299370 0 Interface geometry conserved with 1lb3 (80%) -- Annotation transfered from 1ies 1hsg NO 2 2 C2 C2 7929352 7929352 -- Annotation transfered from 1ajx 1hsh_1 NO 2 2 C2 C2 7929352 7613867 - automatic transfer from 1hii 1hsh_2 NO 2 2 C2 C2 7929352 7613867 - automatic transfer from 1hii 1hsi NO 2 2 C2 C2 7929352 7929352 -- Annotation transfered from 1hii 1hsl PROBYES 2 1 NS NPS 8161536 8161536 Paper not available - Very small interface, it cannot possibly stabilize the dimer, plus monomeric homologs and PISA says monomer 1hso NO 2 2 C2 C2 11274460 11274460 Dimer of identical or non-identical chains of three types - gene dup - interesting 1hsr PROBNOT 1 1 NPS NPS 9257700 9257700 Peroxidases seem to be monomeric in general -- Annotation transfered from 1gza 1hsw NO 1 1 NPS NPS 10089340 10089340 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1hsx NO 1 1 NPS NPS 10089340 10089340 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1hsy NO 1 1 NPS NPS 7654702 7654702 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1hsz NO 2 2 C2 C2 11274460 11274460 Dimer of identical or non-identical chains of three types - gene dup - interesting -- Annotation transfered from 1hdx 1ht0 NO 2 2 C2 C2 11274460 11274460 Dimer of identical or non-identical chains of three types - gene dup - interesting 1ht1_3 NO 6 6 C6 C6 11709174 10693812 HSLU is the outer ring so it forms a hexamer (not a dodecamer) - automatic transfer from 1do0 1ht1_4 PROBYES 6 6 NS C6 11709174 10693812 BU changed since last release and is now incorrect - HSLU is the outer ring so it forms a hexamer (not a dodecamer) - automaticaly inferred from 1do0 1ht2_2 NO 6 6 C6 C6 11709174 10693812 HSLU is the outer ring so it forms a hexamer (not a dodecamer) - automatic transfer from 1do0 1ht2_5 NO 6 6 C6 C6 11709174 10693812 HSLU is the outer ring so it forms a hexamer (not a dodecamer) - automatic transfer from 1do0 1ht3 PROBNOT 1 1 NPS NPS 11886076 11886076 -- Annotation transfered from 1p7v 1ht5 NO 2 2 C2 C2 11318639 11318639 -- Annotation transfered from 1cqe 1ht6 NO 1 1 NPS NPS 12906828 12906828 alpha-Amylases (a-1,4 glucan-4-glucanohydrolase, EC 3.2.1.1) are monomeric enzymes that catalyse the hydrolysis of internal a-D-(1,4) glucosidic linkages in starch and related oligo- and polysaccharides with release of malto-oligosaccharides and glucose in the alpha-anomeric form. -- Annotation transfered from 1p6w 1ht8 NO 2 2 C2 C2 11318639 11318639 -- Annotation transfered from 1cqe 1ht9 NO 2 2 C2 C2 11316872 11316872 Domain swapped dimer obtained with 2 mutations 1htb NO 2 2 C2 C2 8663387 8663387 Dimer of identical or non-identical chains of three types - gene dup - interesting -- Annotation transfered from 1hdx 1htd PROBYES 2 1 C2 NPS 8078901 8078901 Papers say nothing and PISA says monomer -- Annotation transfered from 1dth 1hte NO 2 2 C2 C2 8031777 8031777 -- Annotation transfered from 1ajx 1htf NO 2 2 C2 C2 8031777 8031777 -- Annotation transfered from 1ajx 1htg NO 2 2 C2 C2 8031777 8031777 -- Annotation transfered from 1ajx 1hti NO 2 2 C2 C2 8061610 8061610 Interface geometry conserved with 1m6j (50%) -- Annotation transfered from 1r2t 1htp PROBNOT 1 1 NPS NPS 7719855 7719855 1htz_1 PROBNOT 1 1 NPS NPS 11224569 12079336 EcoCyc says monomer - automatic transfer from 1jwp 1htz_2 PROBNOT 1 1 NPS NPS 11224569 12079336 EcoCyc says monomer - automatic transfer from 1jwp 1htz_3 PROBNOT 1 1 NPS NPS 11224569 12079336 EcoCyc says monomer - automatic transfer from 1jwp 1htz_4 PROBNOT 1 1 NPS NPS 11224569 12079336 EcoCyc says monomer - automatic transfer from 1jwp 1htz_5 PROBNOT 1 1 NPS NPS 11224569 12079336 EcoCyc says monomer - automatic transfer from 1jwp 1htz_6 PROBNOT 1 1 NPS NPS 11224569 12079336 EcoCyc says monomer - automatic transfer from 1jwp 1hug NO 1 1 NPS NPS 15299369 0 10529183 says monomer -- Annotation transfered from 1crm 1huh NO 1 1 NPS NPS 15299369 0 10529183 says monomer -- Annotation transfered from 1crm 1huj PROBNOT 2 2 C2 C2 0 0 SP says dimer -- Annotation transfered from 1wgi 1huk PROBNOT 2 2 C2 C2 0 0 SP says dimer -- Annotation transfered from 1wgi 1huq PROBNOT 1 1 NPS NPS 11278565 11278565 1hur PROBYES 2 1 C2 NPS 7990966 7990966 Might form a dimer when anchored to the membrane but is monomeric in solution -- Annotation transfered from 1rrg 1huw PROBNOT 2 2 C2 C2 8107110 8107110 SP says: Monomer, dimer, trimer, tetramer and pentamer, disulfide-linked or non-covalently associated, in homopolymeric and heteropolymeric combinations. Can also form a complex either with GHBP or with the alpha2-macroglobulin complex -- family remark: again, good example to show that secreted proteins are not well defined and very versatile in terms of their oligomeric states. 1huy NO 1 1 NPS NPS 11387331 11387331 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1hv0 PROBNOT 1 1 NPS NPS 11513590 11513590 Paper says nothing and PISA says monomer -- Annotation transfered from 1xnb 1hv1 PROBNOT 1 1 NPS NPS 11513590 11513590 Paper says nothing and PISA says monomer -- Annotation transfered from 1xnb 1hv7 PROBNOT 1 1 NPS NPS 11294386 11294386 -- Annotation transfered from 1c1m 1hva PROBNOT 1 1 NPS NPS 8431430 8431430 9000633 says monomeric -- Annotation transfered from 1uga 1hvb PROBNOT 1 1 NPS NPS 11171967 11171967 the Streptomyces R61 and Actinomadura R39 DD-peptidases, are water-soluble monomeric proteins; (12723972) -- Annotation transfered from 1pwd 1hvc YES 1 1 NPS NPS 7664084 7664084 SCOP error, only one domain is defined but there are two that are fused. 1hvd PROBNOT 1 1 NPS NPS 8151707 8151707 11099380SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1avr 1hve PROBNOT 1 1 NPS NPS 8151707 8151707 11099380SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1avr 1hvf PROBNOT 1 1 NPS NPS 8151707 8151707 11099380SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1avr 1hvg PROBNOT 1 1 NPS NPS 8151707 8151707 11099380SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1avr 1hvh NO 2 2 C2 C2 9554878 9554878 -- Annotation transfered from 1ajx 1hvi NO 2 2 C2 C2 -1 0 -- Annotation transfered from 1ajx 1hvj NO 2 2 C2 C2 -1 0 -- Annotation transfered from 1ajx 1hvk NO 2 2 C2 C2 -1 0 -- Annotation transfered from 1ajx 1hvl NO 2 2 C2 C2 -1 0 -- Annotation transfered from 1ajx 1hvq PROBNOT 1 1 NPS NPS 7704528 7704528 -- Annotation transfered from 1kr1 1hvr NO 2 2 C2 C2 8278812 8278812 -- Annotation transfered from 1ajx 1hvs NO 2 2 C2 C2 7773792 7773792 -- Annotation transfered from 1ajx 1hvx PROBNOT 1 1 NPS NPS 11226887 11226887 SP says monomer 1hvy_1 NO 2 2 C2 C2 11329255 11278511 SP says dimer - automatic transfer from 1hw4 1hvy_2 NO 2 2 C2 C2 11329255 11278511 SP says dimer - automatic transfer from 1hw4 1hw1 NO 2 2 C2 C2 11279025 11279025 -- Annotation transfered from 1e2x 1hw2 NO 2 2 C2 C2 11279025 11279025 -- Annotation transfered from 1e2x 1hw3 NO 2 2 C2 C2 11278511 11278511 SP says dimer -- Annotation transfered from 1hw4 1hw4 NO 2 2 C2 C2 11278511 11278511 SP says dimer 1hw6 NA 1 1 NPS NPS 11399090 11399090 SwissProt says monomer but PISA says dimer. The contacts established in the dimeric form are also found in 1ef3 which is a bit puzzling. --> investigate more - interesting case. -- Annotation transfered from 1m9h 1hw8 NO 4 4 D2 D2 11349148 11349148 Paper says: The crystallographic analysis, as well as solution studies, reveals that the catalytic portion of human HMGR is a tetramer, suggesting a revised mechanism of sterol sensing by HMGR. -- Annotation transfered from 1dq8 1hw9 NO 4 4 D2 D2 11349148 11349148 Paper says: The crystallographic analysis, as well as solution studies, reveals that the catalytic portion of human HMGR is a tetramer, suggesting a revised mechanism of sterol sensing by HMGR. -- Annotation transfered from 1dq8 1hwi NO 4 4 D2 D2 11349148 11349148 Paper says: The crystallographic analysis, as well as solution studies, reveals that the catalytic portion of human HMGR is a tetramer, suggesting a revised mechanism of sterol sensing by HMGR. -- Annotation transfered from 1dq8 1hwj NO 4 4 D2 D2 11349148 11349148 Paper says: The crystallographic analysis, as well as solution studies, reveals that the catalytic portion of human HMGR is a tetramer, suggesting a revised mechanism of sterol sensing by HMGR. -- Annotation transfered from 1dq8 1hwk NO 4 4 D2 D2 11349148 11349148 Paper says: The crystallographic analysis, as well as solution studies, reveals that the catalytic portion of human HMGR is a tetramer, suggesting a revised mechanism of sterol sensing by HMGR. -- Annotation transfered from 1dq8 1hwl NO 4 4 D2 D2 11349148 11349148 Paper says: The crystallographic analysis, as well as solution studies, reveals that the catalytic portion of human HMGR is a tetramer, suggesting a revised mechanism of sterol sensing by HMGR. -- Annotation transfered from 1dq8 1hwr NO 2 2 C2 C2 9575185 9575185 -- Annotation transfered from 1ajx 1hwt_1 PROBNOT 2 2 NS NS 9886294 9886294 Paper says: The structure reveals that HAP1 is bound in a dramatically asymmetric manner to the DNA target. 1hwt_2 PROBNOT 2 2 NS NS 9886294 9886294 Paper says: The structure reveals that HAP1 is bound in a dramatically asymmetric manner to the DNA target. - automatic transfer from 1hwt_1 1hx3_1 PROBNOT 1 1 NPS NPS 11285217 12540835 BU changed since last release and is now corrected - Seems to be a monomer - PISA would be wrong - automaticaly inferred from 1nfs 1hx3_2 PROBNOT 1 1 NPS NPS 11285217 12540835 BU changed since last release and is now corrected - Seems to be a monomer - PISA would be wrong - automaticaly inferred from 1nfs 1hx9 PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 5eau 1hxa PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 5eau 1hxb NO 2 2 C2 C2 1956054 1956054 -- Annotation transfered from 1ajx 1hxc PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 5eau 1hxg PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 5eau 1hxh NO 4 4 D2 D2 12475215 12475215 paper says tetramer 1hxj PROBNOT 2 2 C2 C2 11706179 11706179 Paper says: It was unexpected that the E401D as well as C205S and C211S mutations dramatically impaired the assembly of a catalysis-competent homodimer, suggesting novel links between the active site structure and dimer formation. -- Interesting: link between dimer formation and catalysis 1hxl NO 4 4 D2 D2 0 0 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1hxn PROBNOT 1 1 NPS NPS 8590016 8590016 Paper says nothing and PISA says monomer 1hxt NO 3 3 C3 C3 11371193 11371193 Interface geometry conserved with 1prn (20%) -- Annotation transfered from 1gfn 1hxu NO 3 3 C3 C3 11371193 11371193 Interface geometry conserved with 1prn (20%) -- Annotation transfered from 1gfn 1hxw NO 2 2 C2 C2 7708670 7708670 -- Annotation transfered from 1ajx 1hxx NO 3 3 C3 C3 11371193 11371193 Interface geometry conserved with 1prn (20%) -- Annotation transfered from 1gfn 1hxz NO 4 4 D2 D2 0 0 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1hy0 NO 4 4 D2 D2 11258884 11258884 Interface geometry conserved with 1fur (23%) 1hy1 NO 4 4 D2 D2 11258884 11258884 Interface geometry conserved with 1fur (23%) -- Annotation transfered from 1tjw 1hy2 NO 4 4 D2 D2 0 0 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1hy3 NO 2 2 C2 C2 11884392 11884392 Paper says: These loops form the identical interaction as seen in human hydroxysteroid sulfotransferase and human aryl sulfotransferase 3 crystals that has been implicated to be the physiological dimerization interface. Apparently, the V269E mutation did not prevent the hEST from forming the proper dimer in the crystal lattice. - this interface does contain residue 269 so it is probably the good one 1hy7_1 PROBNOT 1 1 NPS NPS 11297453 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1hy7_2 PROBNOT 1 1 NPS NPS 11297453 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1hyb NO 6 6 D3 D3 11063748 11063748 -- Annotation transfered from 1m8g 1hye NO 2 2 C2 C2 11292347 11292347 Paper says: Dynamic light-scattering measurements indicated that [...] the MJ0490 gene product exists in solution predominantly as a tetramer. - The P-axis subunit interface area is increased from 1760 Å2 in the tetrameric enzyme to 2001 Å2 in the dimeric enzyme. - Interesting that the dimer observed here does not correspond to the "evolutionary dimer", they say: The reason why the MJ0490 enzyme dissociates into P-dimers but not into Q-dimers may be the more polar character of the P-axis subunit interface compared with the Q-axis subunit interface. -- very interesting family! Paper says a lot 1hyg NO 4 4 D2 D2 11292347 11292347 Paper says: Dynamic light-scattering measurements indicated that [...] the MJ0490 gene product exists in solution predominantly as a tetramer. - The P-axis subunit interface area is increased from 1760 Å2 in the tetrameric enzyme to 2001 Å2 in the dimeric enzyme. - Interesting that the dimer observed here does not correspond to the "evolutionary dimer", they say: The reason why the MJ0490 enzyme dissociates into P-dimers but not into Q-dimers may be the more polar character of the P-axis subunit interface compared with the Q-axis subunit interface. -- very interesting family! Paper says a lot 1hyh NO 4 4 D2 D2 7643402 7643402 Paper says tetramer 1hyl PROBYES 4 1 C2 NPS 15299709 0 Paper says: The collagenase purified from H. lineatum larvae is a monomeric enzyme of molecular weight 25 223 Da - Although tetrameric collagenases exist in other organisms - potentialy interessting -- Annotation transfered from 2hlc 1hyp PROBNOT 1 1 NPS NPS 8515457 8515457 PISA says monomer, consistent with family 1hyt PROBNOT 2 2 C2 C2 8034637 8034637 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 8tln 1hyv NO 2 2 C2 C2 11264582 11264582 Often described as a dimer (sometimes tetramer), and convincingly a similar dimer (same interface) is found in 1a5v (30% id). -- Annotation transfered from 1itg 1hyz NO 2 2 C2 C2 11264582 11264582 Often described as a dimer (sometimes tetramer), and convincingly a similar dimer (same interface) is found in 1a5v (30% id). -- Annotation transfered from 1itg 1hz5_1 PROBYES 1 2 NPS C2 11264576 11709166 BU changed since last release and is now incorrect - Domain Swapped dimer - automaticaly inferred from 1k51 1hz5_2 PROBYES 1 2 NPS C2 11264576 11709166 BU changed since last release and is now incorrect - Domain Swapped dimer - automaticaly inferred from 1k51 1hz6_1 PROBYES 1 2 NPS C2 11264576 11709166 BU changed since last release and is now incorrect - Domain Swapped dimer - automaticaly inferred from 1k51 1hz6_2 PROBYES 1 2 NPS C2 11264576 11709166 BU changed since last release and is now incorrect - Domain Swapped dimer - automaticaly inferred from 1k51 1hz6_3 PROBYES 1 2 NPS C2 11264576 11709166 BU changed since last release and is now incorrect - Domain Swapped dimer - automaticaly inferred from 1k51 1hz9 PROBYES 2 1 C2 NPS 11800562 11800562 Monomeric in most conditions (9501917) -- Annotation transfered from 1hzc 1hza PROBYES 2 1 C2 NPS 11800562 11800562 Monomeric in most conditions (9501917) -- Annotation transfered from 1hzc 1hzb YES 2 1 NS NPS 11800562 11800562 Paper says monomeric based on 9501917 1hzc PROBYES 2 1 C2 NPS 11800562 11800562 Monomeric in most conditions (9501917) 1hzd NO 6 6 D3 D3 11738050 11738050 paper says hexamer -- PISA says the same, although the interface seems weak 1hzf NO 1 1 NPS NPS 12367531 12367531 The various C4d derivatives behaved as monomers on a calibrated Superdex-200 FPLC gel filtration column as long as they were maintained in DTT-containing buffers. However, if the reducing agent was omitted, disulfide-linked dimers readily formed. Since this phenomenon occurred with C4d derivatives of either isotype, and since the thioester cysteine (C991) is the only one present in C4B isotype derivatives, we concluded that disulfide-linked dimer formation occurred via C991. 1hzi PROBNOT 1 1 NPS NPS 11526337 11526337 1hzj NO 2 2 C2 C2 11279032 11279032 Paper says dimer -- Annotation transfered from 1i3l 1hzp NO 2 2 C2 C2 11278743 11278743 -- Annotation transfered from 1m1m 1hzt PROBNOT 1 1 NPS NPS 11285217 11285217 -- Annotation transfered from 1r67 1hzw NO 2 2 C2 C2 11316879 11316879 SP says dimer -- Annotation transfered from 1hw4 1i00 NO 2 2 C2 C2 11316879 11316879 SP says dimer -- Annotation transfered from 1hw4 1i01_1 NO 4 4 D2 D2 11669613 15016358 Swissprot says homotetramer - automatic transfer from 1q7c 1i04 PROBNOT 1 1 NPS NPS 11316880 11316880 Gel filtration performed and no dimer or oligomer mentioned. -- Annotation transfered from 1i06 1i05 PROBNOT 1 1 NPS NPS 11316880 11316880 Gel filtration performed and no dimer or oligomer mentioned. -- Annotation transfered from 1i06 1i06 PROBNOT 1 1 NPS NPS 11316880 11316880 Gel filtration performed and no dimer or oligomer mentioned. 1i07 NO 2 2 C2 C2 11316885 11316885 SwissProt says homodimer 1i08_1 NO 2 2 C2 C2 11294629 11294629 PAper, SP say dimer - automatic transfer from 1i0h 1i08_2 NO 2 2 C2 C2 11294629 11294629 PAper, SP say dimer - automatic transfer from 1i0h 1i09_1 YES 1 2 NPS C2 11427888 11440715 Paper says dimer detected in solution but the functional significance is unclear (autoinhibition is a possibility) - monomer/dimer equilibrium - automatic transfer from 1o9u 1i09_2 YES 1 2 NPS C2 11427888 11440715 Paper says dimer detected in solution but the functional significance is unclear (autoinhibition is a possibility) - monomer/dimer equilibrium - automatic transfer from 1o9u 1i0a NO 4 4 D2 D2 11258884 11258884 Interface geometry conserved with 1vdk (23%) 1i0c_1 PROBYES 1 2 NPS C2 11316885 11316885 BU changed since last release and is now incorrect - SwissProt says homodimer - automaticaly inferred from 1i07 1i0c_2 PROBYES 1 2 NPS C2 11316885 11316885 BU changed since last release and is now incorrect - SwissProt says homodimer - automaticaly inferred from 1i07 1i0h NO 2 2 C2 C2 11294629 11294629 PAper, SP say dimer 1i0i NO 2 2 C2 C2 11258886 11258886 PID 12070315: Of the 6-oxopurine PRTase structures currently in the literature, four are tetramers (human HGPRT, T. gondii HGXPRT, E. coli XGPRT, and P. falciparum HGXPRT) and three are dimers (G. lamblia GPRT, T. foetus HGXPRT, and T. cruzi HGPRT). -- Annotation transfered from 1p18 1i0l NO 2 2 C2 C2 11258886 11258886 PID 12070315: Of the 6-oxopurine PRTase structures currently in the literature, four are tetramers (human HGPRT, T. gondii HGXPRT, E. coli XGPRT, and P. falciparum HGXPRT) and three are dimers (G. lamblia GPRT, T. foetus HGXPRT, and T. cruzi HGPRT). -- Annotation transfered from 1p18 1i0z NO 4 4 D2 D2 11276087 11276087 Paper says tetramer - interesting: two isoforms of the enzyme can combine with each other. 1i12_1 NO 2 2 C2 C2 11278591 11278591 Paper says homodimer 1i12_2 NO 2 2 C2 C2 11278591 11278591 Paper says homodimer -- Annotation transfered from 1i12_1 1i13 NO 2 2 C2 C2 11258886 11258886 PID 12070315: Of the 6-oxopurine PRTase structures currently in the literature, four are tetramers (human HGPRT, T. gondii HGXPRT, E. coli XGPRT, and P. falciparum HGXPRT) and three are dimers (G. lamblia GPRT, T. foetus HGXPRT, and T. cruzi HGPRT). -- Annotation transfered from 1p18 1i14 NO 2 2 C2 C2 11258886 11258886 PID 12070315: Of the 6-oxopurine PRTase structures currently in the literature, four are tetramers (human HGPRT, T. gondii HGXPRT, E. coli XGPRT, and P. falciparum HGXPRT) and three are dimers (G. lamblia GPRT, T. foetus HGXPRT, and T. cruzi HGPRT). -- Annotation transfered from 1p18 1i1b PROBNOT 1 1 NPS NPS 2585509 2585509 SP says monomer -- Annotation transfered from 21bi 1i1c PROBNOT 2 2 C2 C2 11336709 11336709 1i1d_1 NO 2 2 C2 C2 11278591 11278591 Paper says homodimer -- Annotation transfered from 1i12_1 1i1d_2 NO 2 2 C2 C2 11278591 11278591 Paper says homodimer -- Annotation transfered from 1i12_1 1i1g NO 8 8 D4 D4 11230123 11230123 Paper says: Gel filtration experiments with concentrated protein samples suggest that LrpA forms a mixture of dimeric, tetrameric and octameric species at neutral pH, and an octamer below pH 6.0 - equilibrium -- interesting: no hexameric intermediate. Good example for work with Elisabetta. 1i1h NO 2 2 C2 C2 11470433 11470433 Interface geometry conserved with 1f2v (43%) -- Annotation transfered from 1f2v 1i1k NO 6 6 D3 D3 11412098 11412098 Paper says hexamer - SP too -- Annotation transfered from 1iyd 1i1l NO 6 6 D3 D3 11412098 11412098 Paper says hexamer - SP too -- Annotation transfered from 1iyd 1i1m NO 6 6 D3 D3 11412098 11412098 Paper says hexamer - SP too -- Annotation transfered from 1iyd 1i1n PROBNOT 1 1 NPS NPS 11847284 11847284 SP says monomer 1i1o PROBNOT 1 1 NPS NPS 11264581 11264581 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1f4p 1i1z NO 1 1 NPS NPS 9852096 9852096 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1i20 NO 1 1 NPS NPS 9852096 9852096 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1i21_1 NO 2 2 C2 C2 11278591 11278591 Paper says homodimer -- Annotation transfered from 1i12_1 1i21_2 NO 2 2 C2 C2 11278591 11278591 Paper says homodimer -- Annotation transfered from 1i12_1 1i21_3 NO 2 2 C2 C2 11278591 11278591 Paper says homodimer -- Annotation transfered from 1i12_1 1i22_1 NO 1 1 NPS NPS 9852096 7990138 Lysozyme C is monomeric - automatic transfer from 1lzr 1i22_2 NO 1 1 NPS NPS 9852096 7990138 Lysozyme C is monomeric - automatic transfer from 1lzr 1i22_3 NO 1 1 NPS NPS 9852096 7990138 Lysozyme C is monomeric - automatic transfer from 1lzr 1i22_4 NO 1 1 NPS NPS 9852096 7990138 Lysozyme C is monomeric - automatic transfer from 1lzr 1i24 NO 2 2 C2 C2 0 0 Paper says dimer -- Annotation transfered from 1qrr 1i29 NO 2 2 C2 C2 11983074 11983074 1i2b NO 2 2 C2 C2 0 0 Paper says dimer -- Annotation transfered from 1qrr 1i2c NO 2 2 C2 C2 0 0 Paper says dimer -- Annotation transfered from 1qrr 1i2h NO 1 1 NPS NPS 12054806 12054806 We also confirmed that CRH1 formed a monomer structure in solution by analytical centrifuge measurements as well as the small-angle X-ray scattering (SAXS) method, while the crystal structure showed intermolecular interactions with the neighbouring molecules in the crystal lattice. 1i2k NO 2 2 C2 C2 0 0 Homodimer 1i2l NO 2 2 C2 C2 0 0 Homodimer -- Annotation transfered from 1i2k 1i2s PROBYES 2 1 C2 NPS 11827533 11827533 Paper says nothing and PISA says monomeric -- Annotation transfered from 1i2w 1i2w PROBYES 2 1 C2 NPS 11827533 11827533 Paper says nothing and PISA says monomeric 1i2z NO 4 4 D2 D2 11514139 11514139 -- Annotation transfered from 1c14 1i30 NO 4 4 D2 D2 11514139 11514139 -- Annotation transfered from 1c14 1i32_1 NO 4 4 D2 D2 11371162 9571030 SP says tetramer - papers too - automatic transfer from 1a7k 1i32_2 NO 4 4 D2 D2 11371162 9571030 SP says tetramer - papers too - automatic transfer from 1a7k 1i33_1 NO 4 4 D2 D2 11371162 9571030 SP says tetramer - papers too - automatic transfer from 1a7k 1i33_2 NO 4 4 D2 D2 11371162 9571030 SP says tetramer - papers too - automatic transfer from 1a7k 1i37 PROBNOT 1 1 NPS NPS 11320241 11320241 paper does not mention dimer and PISA says monomer -- Annotation transfered from 1e3g 1i38 PROBNOT 1 1 NPS NPS 11320241 11320241 paper does not mention dimer and PISA says monomer -- Annotation transfered from 1e3g 1i39 PROBNOT 1 1 NPS NPS 11254381 11254381 Paper says nothing, PISA says monomer -- Annotation transfered from 1i3a 1i3a PROBNOT 1 1 NPS NPS 11254381 11254381 Paper says nothing, PISA says monomer 1i3d NO 4 4 D2 D2 11514664 11514664 SP says: Heterotetramer of two alpha chains and two gamma chains in fetal hemoglobin (Hb F). In the case of deletions affecting one or more of the alpha chains the excess gamma chains form homotetramers that exhibit neither Bohr effect nor heme-heme cooperativity (hemoglobin Barts). -- Annotation transfered from 1i3e 1i3e NO 4 4 D2 D2 11514664 11514664 SP says: Heterotetramer of two alpha chains and two gamma chains in fetal hemoglobin (Hb F). In the case of deletions affecting one or more of the alpha chains the excess gamma chains form homotetramers that exhibit neither Bohr effect nor heme-heme cooperativity (hemoglobin Barts). 1i3h NO 4 4 D2 D2 11453694 11453694 SP says tetramer -- Annotation transfered from 1cjp 1i3k NO 2 2 C2 C2 11279193 11279193 Paper says dimer -- Annotation transfered from 1i3l 1i3l NO 2 2 C2 C2 11279193 11279193 Paper says dimer 1i3m NO 2 2 C2 C2 11279193 11279193 Paper says dimer -- Annotation transfered from 1i3l 1i3n NO 2 2 C2 C2 11279193 11279193 Paper says dimer -- Annotation transfered from 1i3l 1i3q NO 10 10 NPS NPS 11313498 11313498 Correct complex. 1i3u NO 1 1 NPS NPS 11469862 10684599 Paper says monomeric 1i3v_1 NO 1 1 NPS NPS 11469862 10684599 Paper says monomeric - automatic transfer from 1i3u 1i3v_2 NO 1 1 NPS NPS 11469862 10684599 Paper says monomeric - automatic transfer from 1i3u 1i3z PROBNOT 1 1 NPS NPS 11689425 11689425 1i40 NO 6 6 D3 D3 11846572 11846572 SP and EcoCyc say hexamer -- Annotation transfered from 1mjz 1i44 PROBNOT 1 1 NPS NPS 11124964 11124964 -- Annotation transfered from 1gag 1i45 NO 2 2 C2 C2 11419952 11419952 Interface geometry conserved with 1m6j (43%) -- Annotation transfered from 7tim 1i4a PROBNOT 1 1 NPS NPS 11300800 11300800 SP says monomer -- Annotation transfered from 1aow 1i4j PROBYES 2 1 C2 NPS 12225755 12225755 Paper implies it is a monomer and PISA agrees 1i4k_1 NO 7 7 C7 C7 11331594 11331594 Interface conserved with 1n9s (33% id) -- Annotation transfered from 1i4k_4 1i4k_2 NO 7 7 C7 C7 11331594 11331594 Interface conserved with 1n9s (33% id) -- Annotation transfered from 1i4k_4 1i4k_3 NO 7 7 C7 C7 11331594 11331594 Interface conserved with 1n9s (33% id) -- Annotation transfered from 1i4k_4 1i4k_4 NO 7 7 C7 C7 11331594 11331594 Interface conserved with 1n9s (33% id) 1i4p PROBNOT 1 1 NPS NPS 11526318 11526318 dimer not mentioned in literature, PISA says monomer 1i4q PROBNOT 1 1 NPS NPS 11526318 11526318 dimer not mentioned in literature, PISA says monomer -- Annotation transfered from 1i4p 1i4r PROBNOT 1 1 NPS NPS 11526318 11526318 dimer not mentioned in literature, PISA says monomer -- Annotation transfered from 1i4p 1i4u PROBNOT 2 2 C2 C2 11526314 11526314 SP says: Oligomer; Can form dimers (beta-crustacyanin); or complexes of 16 subunits (alpha-crustacyanin). There are five types of subunits: A1, A2, A3, C1 and C2 -- Annotation transfered from 1s2p 1i4x PROBNOT 1 1 NPS NPS 11526318 11526318 dimer not mentioned in literature, PISA says monomer -- Annotation transfered from 1i4p 1i4y NA 8 8 D4 D4 11372200 11372200 Paper not free - send email 1i4z NA 8 8 D4 D4 11372200 11372200 Paper not free - send email -- Annotation transfered from 1i4y 1i50 NO 10 10 NPS NPS 11313498 11313498 Correct complex. -- Annotation transfered from 1i3q 1i52 NO 2 2 C2 C2 11427897 11427897 Paper says dimer: CDP-ME synthetase organizes as a homodimer with each subunit related by a crystallographic two-fold axis - SP says dimer too -- Annotation transfered from 1ini 1i53_1 PROBNOT 1 1 NPS NPS 11457048 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1i53_2 PROBNOT 1 1 NPS NPS 11457048 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1i54_1 PROBNOT 1 1 NPS NPS 11296248 0 - automatic transfer from 5cyt 1i54_2 PROBNOT 1 1 NPS NPS 11296248 0 - automatic transfer from 5cyt 1i55_1 PROBNOT 1 1 NPS NPS 11296248 0 - automatic transfer from 5cyt 1i55_2 PROBNOT 1 1 NPS NPS 11296248 0 - automatic transfer from 5cyt 1i57 PROBNOT 1 1 NPS NPS 11468356 15817824 Apparently it can also exist in a dimeric form 1i58 NO 2 2 C2 C2 11276258 11276258 PISA seem to be wrong 1i59 YES 2 2 NS C2 11276258 11276258 PISA seem to be wrong 1i5a YES 2 2 NS C2 11276258 11276258 PISA seem to be wrong -- Annotation transfered from 1i59 1i5b YES 2 2 NS C2 11276258 11276258 PISA seem to be wrong -- Annotation transfered from 1i59 1i5c NO 2 2 C2 C2 11276258 11276258 PISA seem to be wrong -- Annotation transfered from 1i58 1i5d YES 1 2 NPS C2 11276258 11276258 PISA seem to be wrong 1i5e NO 2 2 C2 C2 12037295 12037295 UPRTase from B. caldolyticus forms a dimer with the active sites pointing away from each other. A long arm from each subunit wraps around the other subunit, contributing half of the dimer interface. 1i5f PROBYES 2 1 C2 NPS 11800562 11800562 Monomeric in most conditions (9501917) -- Annotation transfered from 1hzc 1i5g PROBNOT 1 1 NPS NPS 11347894 11347894 Paper says S-S oxidized 1i5i PROBNOT 1 1 NPS NPS 11733987 11733987 y-Crystallins are exclusively monomeric -- Annotation transfered from 1gcs 1i5l_1 NO 7 7 C7 C7 11331594 11331594 Interface conserved with 1n9s (33% id) -- Annotation transfered from 1i4k_4 1i5l_2 NO 7 7 C7 C7 11331594 11331594 Interface conserved with 1n9s (33% id) -- Annotation transfered from 1i4k_4 1i5o NO 12 12 D3 D3 11323717 11323717 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1i5q_1 PROBNOT 1 1 NPS NPS 11434768 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1i5q_2 PROBNOT 1 1 NPS NPS 11434768 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1i5r NO 2 2 C2 C2 12223444 12223444 Paper says dimer -- Annotation transfered from 3dhe 1i5s NO 1 1 NPS NPS 11373668 11373668 Missing dimerization coil-coil -- Annotation transfered from 1vfz 1i69 NO 2 2 C2 C2 11301006 11301006 Paper shows it is a dimer - even a tetramer but for that I guess it d need DNA - EcoCyc is wrong - PISA is right 1i6a YES 1 2 NPS C2 11301006 11301006 Paper shows a dimer 1i6h NO 10 10 NPS NPS 11313499 11313498 Correct complex. -- Annotation transfered from 1i3q 1i6i NO 1 1 NPS NPS 11373668 11373668 Missing dimerization coil-coil -- Annotation transfered from 1vfz 1i6j NO 1 1 NPS NPS 11526315 11526315 Active as a monomer - Although HIV RT is active as a dimer (see ref) -- Annotation transfered from 1rw3 1i6s NO 1 1 NPS NPS 11316887 11316887 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1i6t NO 6 6 D3 D3 11846572 11846572 SP and EcoCyc say hexamer -- Annotation transfered from 1mjz 1i6w PROBYES 2 1 C2 NPS 11491291 11491291 PISa says monomer and related proteins are monomeric + paper says: The lipase eluted as one sharp peak at a volume that corresponded to an apparent molecular mass that is smaller (<10 kDa) than expected (19 kDa), but with no aggregates in the void volume. In addition, dynamic light-scattering measurements were carried out with a solution of 6 mg/ml protein in 2 to 6 mM glycine buffer (pH 10). These experiments showed only monomeric protein. 1i70_1 PROBNOT 1 1 NPS NPS 11554795 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1i70_2 PROBNOT 1 1 NPS NPS 11554795 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1i71 PROBNOT 1 1 NPS NPS 11369850 11369850 Real protein 4500 aa! So monomeric seems right 1i73 PROBNOT 1 1 NPS NPS 10978185 10978185 No clear evidence after a quick search but PISA agrees ... -- Annotation transfered from 1a85 1i75 PROBYES 2 1 C2 NPS 11275559 11275559 Cyclodextrin - glycosyltransferases are monomeric, paper implies that this one is, SP and PISA too. -- Annotation transfered from 1d7f 1i76 PROBNOT 1 1 NPS NPS 10978185 10978185 No clear evidence after a quick search but PISA agrees ... -- Annotation transfered from 1a85 1i77 NO 1 1 NPS NPS 11358521 11358521 Paper says monomeric: Cytochrome c3, the marker protein of the genus Desulfovibrio, is a small (106–118 residues, monomeric) soluble tetraheme protein located in the periplasmic space. - PISA says monomeric too 1i7d PROBNOT 1 1 NPS NPS 11429611 11429611 EcoCyc says monomer 1i7g PROBNOT 1 1 NPS NPS 11587644 11587644 SP says: Heterodimer with the retinoid X receptor. 1i7i_1 PROBYES 1 2 NPS C2 11587644 15258145 PISA says homodimer and identicals are homodimers - automatic transfer from 1wm0 1i7i_2 PROBYES 1 2 NPS C2 11587644 15258145 PISA says homodimer and identicals are homodimers - automatic transfer from 1wm0 1i7l PROBYES 2 4 C2 D2 0 0 No paper found - Email sent - Answer: We dont have data on the native oligomeric state of the synapsin C domains. This is because the C domains are parts of larger proteins, which may behave differently and are much more difficult to handle than the C domains alone. In vitro, the synapsin C domains do form tetramers; the binding of ATP increases the stability of the tetramers. -- Annotation transfered from 1i7n 1i7n PROBYES 2 4 C2 D2 0 0 No paper found - Email sent - Answer: We dont have data on the native oligomeric state of the synapsin C domains. This is because the C domains are parts of larger proteins, which may behave differently and are much more difficult to handle than the C domains alone. In vitro, the synapsin C domains do form tetramers; the binding of ATP increases the stability of the tetramers. 1i7p NO 1 1 NPS NPS 11695905 11695905 -- Annotation transfered from 1ib0 1i80 NO 3 3 C3 C3 11444966 11444966 Paper says trimer -- Annotation transfered from 1g2o 1i81 NO 7 7 C7 C7 11399068 12649441 Interface conserved with 1n9s (38% id) -- Annotation transfered from 1jbm 1i83 NO 2 2 C2 C2 11331290 11331290 Clear dimer -- Annotation transfered from 1fol 1i86 NO 2 2 C2 C2 11732902 11732902 -- Annotation transfered from 1d6f 1i88_1 PROBYES 2 2 NS C2 11732902 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1d6f 1i88_2 PROBYES 2 2 NS C2 11732902 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1d6f 1i89_1 PROBYES 2 2 NS C2 11732902 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1d6f 1i89_2 PROBYES 2 2 NS C2 11732902 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1d6f 1i8b_1 PROBYES 2 2 NS C2 11732902 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1d6f 1i8b_2 PROBYES 2 2 NS C2 11732902 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1d6f 1i8d PROBNOT 3 3 NS NS 11377200 11377200 Paper says: The homotrimer consists of an asymmetric assembly of monomers 1i8j NO 8 8 D4 D4 11444968 11444968 Paper says octamer 1i8o PROBNOT 1 1 NPS NPS 11742117 11742117 -- Annotation transfered from 1hh7 1i8p_1 PROBNOT 1 1 NPS NPS 11742117 11742117 BU changed since last release and is now corrected - - automaticaly inferred from 1fj0 1i8p_2 PROBNOT 1 1 NPS NPS 11742117 11742117 BU changed since last release and is now corrected - - automaticaly inferred from 1fj0 1i8p_3 PROBNOT 1 1 NPS NPS 11742117 11742117 BU changed since last release and is now corrected - - automaticaly inferred from 1fj0 1i8p_4 PROBNOT 1 1 NPS NPS 11742117 11742117 BU changed since last release and is now corrected - - automaticaly inferred from 1fj0 1i8v_1 PROBNOT 1 1 NPS NPS 11554795 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1i8v_2 PROBNOT 1 1 NPS NPS 11554795 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1i8z PROBNOT 1 1 NPS NPS 11831900 11831900 9000633 says monomeric -- Annotation transfered from 1uga 1i90 PROBNOT 1 1 NPS NPS 11831900 11831900 9000633 says monomeric -- Annotation transfered from 1uga 1i91 PROBNOT 1 1 NPS NPS 11831900 11831900 9000633 says monomeric -- Annotation transfered from 1uga 1i92 PROBNOT 1 1 NPS NPS 11304524 11304524 Fragment - this domain mediate interaction with other proteins but no homo-interaction is mentioned in the paper - PISA also says monomer -- Annotation transfered from 1g9o 1i9a_1 PROBNOT 1 1 NPS NPS 11698677 12540835 BU changed since last release and is now corrected - Seems to be a monomer - PISA would be wrong - automaticaly inferred from 1nfs 1i9a_2 PROBNOT 1 1 NPS NPS 11698677 12540835 BU changed since last release and is now corrected - Seems to be a monomer - PISA would be wrong - automaticaly inferred from 1nfs 1i9e NO 1 1 NPS NPS 11724527 11724527 Normally forms paralogous dimers - so monomer is right although the non-native form. (PISA wrong) 1i9g YES 1 4 NPS D2 11554794 11554794 Interface geometry conserved with 1i9g (30%) 1i9h NO 4 4 D2 D2 11395489 11395489 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1i9l PROBNOT 1 1 NPS NPS 11572683 11572683 9000633 says monomeric -- Annotation transfered from 1uga 1i9m PROBNOT 1 1 NPS NPS 11572683 11572683 9000633 says monomeric -- Annotation transfered from 1uga 1i9n PROBNOT 1 1 NPS NPS 11572683 11572683 9000633 says monomeric -- Annotation transfered from 1uga 1i9o PROBNOT 1 1 NPS NPS 11572683 11572683 9000633 says monomeric -- Annotation transfered from 1uga 1i9p PROBNOT 1 1 NPS NPS 11572683 11572683 9000633 says monomeric -- Annotation transfered from 1uga 1i9q PROBNOT 1 1 NPS NPS 11572683 11572683 9000633 says monomeric -- Annotation transfered from 1uga 1i9w PROBNOT 1 1 NPS NPS 11301009 11301009 check the paper, this protein is crazy - even though the main state is not monomeric, I put that it is not a mistake because it can adopt different conformations - interesting 1ia1_1 PROBNOT 1 1 NPS NPS 11520201 9374515 BU changed since last release and is now corrected - Paper says nothing - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1ai9 1ia1_2 PROBNOT 1 1 NPS NPS 11520201 9374515 BU changed since last release and is now corrected - Paper says nothing - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1ai9 1ia2_1 PROBNOT 1 1 NPS NPS 11520201 9374515 BU changed since last release and is now corrected - Paper says nothing - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1ai9 1ia2_2 PROBNOT 1 1 NPS NPS 11520201 9374515 BU changed since last release and is now corrected - Paper says nothing - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1ai9 1ia3_1 PROBNOT 1 1 NPS NPS 11520201 9374515 BU changed since last release and is now corrected - Paper says nothing - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1ai9 1ia3_2 PROBNOT 1 1 NPS NPS 11520201 9374515 BU changed since last release and is now corrected - Paper says nothing - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1ai9 1ia4_1 PROBNOT 1 1 NPS NPS 11520201 9374515 BU changed since last release and is now corrected - Paper says nothing - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1ai9 1ia4_2 PROBNOT 1 1 NPS NPS 11520201 9374515 BU changed since last release and is now corrected - Paper says nothing - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1ai9 1ia8 PROBNOT 1 1 NPS NPS 10761933 10761933 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization -- Annotation transfered from 1nvs 1iag PROBYES 2 1 C2 NPS 8223430 8223430 In monomeric metzincins, such as crayfish astacin and adamalysin II -- Annotation transfered from 3aig 1ial PROBNOT 1 1 NPS NPS 10201409 10201409 Paper says: suggesting that both proteins are monomeric under these conditions -- Annotation transfered from 1iq1 1iam NO 2 2 C2 C2 9539703 9539703 7608533 shows that equilibrium exists but shifted towards dimeric form. 1ian PROBNOT 1 1 NPS NPS 9095200 9095200 -- Annotation transfered from 1kv1 1iaq_1 NO 1 1 NPS NPS 11320243 10574788 Ras proteins are monomeric G proteins - automatic transfer from 1ctq 1iaq_2 NO 1 1 NPS NPS 11320243 10574788 Ras proteins are monomeric G proteins - automatic transfer from 1ctq 1iaq_3 NO 1 1 NPS NPS 11320243 10574788 Ras proteins are monomeric G proteins - automatic transfer from 1ctq 1ias NA 5 5 C5 C5 11583628 11583628 Nothing said in the paper. PISA says monomeric 1iat NO 2 2 C2 C2 11371164 11371164 1iau PROBNOT 1 1 NPS NPS 11325591 10361252 Granzyme B is a 32 kDa monomeric 1iav NO 1 1 NPS NPS 10493860 10493860 -- Annotation transfered from 1c9n 1iax NO 2 2 C2 C2 11431475 11431475 - automatic transfer from 1iay 1iay NO 2 2 C2 C2 11431475 11431475 1iaz YES 2 1 C2 NPS 11525171 11525171 SP says: Tetramer in the presence of a lipidic interface. Monomer, in soluble state - Since this is the soluble state, it should be a monomer. - very interesting protein: membrane induced tetramerization 1ib0 NO 1 1 NPS NPS 11695905 11695905 1ib5 NO 2 2 C2 C2 11327787 11327787 Paper says dimer (even though they introduced mutations at the interface the QS is fine) 1ib6_1 NO 2 2 C2 C2 11389141 1507230 Paper says dimer - automatic transfer from 2cmd 1ib6_2 NO 2 2 C2 C2 11389141 1507230 Paper says dimer - automatic transfer from 2cmd 1ibb NO 2 2 C2 C2 11327787 11327787 Paper says dimer (even though they introduced mutations at the interface the QS is fine) -- Annotation transfered from 1ib5 1ibd NO 2 2 C2 C2 11327787 11327787 Paper says dimer (even though they introduced mutations at the interface the QS is fine) -- Annotation transfered from 1ib5 1ibf NO 2 2 C2 C2 11327787 11327787 Paper says dimer (even though they introduced mutations at the interface the QS is fine) -- Annotation transfered from 1ib5 1ibh NO 2 2 C2 C2 11327787 11327787 Paper says dimer (even though they introduced mutations at the interface the QS is fine) -- Annotation transfered from 1ib5 1ibj NO 4 4 D2 D2 11402193 11402193 aCBL exists as an α4 tetramer in solution (Ravanel et al., 1996) and crystalline state. 1ibs NO 6 6 D3 D3 11790837 11790837 -- Annotation transfered from 1dkr 1ic6 PROBNOT 1 1 NPS NPS 11258922 11258922 -- Annotation transfered from 1p7v 1ici YES 2 1 C2 NPS 11336676 11336676 The dimers appear to be nonphysiological, because protein contacts in the asymmetric unit are different in the two crystal forms and they involve nonconserved amino acids and solvent molecules. Dynamic light scattering in solution also shows that SIR2-Af1 exists as a monomer. The apparent monomeric state of SIR2-Af1 differs from that of SIR2, which appears to interact with itself, forming a multimer in vitro. 1icj PROBYES 3 1 NS NPS 9565550 9565550 Paper says monomer: PDF from E. coli, a monomeric protein of 168 residues 1icm NO 1 1 NPS NPS 8253762 8253762 Paper says: large quantities of the native, monomeric protein can be produced in, and readily purified, from Escherichia coli. 1icn NO 1 1 NPS NPS 8253762 8253762 Paper says: large quantities of the native, monomeric protein can be produced in, and readily purified, from Escherichia coli. -- Annotation transfered from 1icm 1ict_1 NO 4 4 D2 D2 11418763 11106758 - automatic transfer from 1g1o 1ict_2 NO 4 4 D2 D2 11418763 11106758 - automatic transfer from 1g1o 1icw PROBNOT 2 2 C2 C2 9141135 9141135 Paper says dimer - but a monomer-dimer equilibrium seems to exist -- Annotation transfered from 3il8 1icx PROBNOT 1 1 NPS NPS 12079359 12079359 Paper does not mention a dimer and PISA says monomer 1ida NO 2 2 C2 C2 7743130 7743130 -- Annotation transfered from 1hii 1idb NO 2 2 C2 C2 7743130 7743130 -- Annotation transfered from 1hii 1idn PROBYES 2 1 C2 NPS 9687375 9687375 Normally forms heterodimer - this contact is too small to be biological -- Annotation transfered from 1bhq 1ido PROBNOT 1 1 NPS NPS 7867070 7867070 1idr NA 2 2 NS C2 11483493 11483493 Gel filtration analysis of the recombinant protein suggested that trHbN has a dimeric assembly (Couture et al., 1999a). --> probably not open, but PISA doesnt find the right one. 1ids NO 4 4 D2 D2 7877174 7877174 Paper says tetramer, SP too 1ie0 NO 2 2 C2 C2 11553770 11553770 1ie3_1 NO 2 2 C2 C2 11389141 1507230 Paper says dimer - automatic transfer from 2cmd 1ie3_2 NO 2 2 C2 C2 11389141 1507230 Paper says dimer - automatic transfer from 2cmd 1ie4 NO 4 4 D2 D2 11468389 11468389 Paper says tetramer -- Annotation transfered from 1gke 1ie7 YES 3 9 NPS C3 11713685 11713685 Interface geometry conserved with 1e2f (64% id avg) -- Annotation transfered from 4ubp 1ie8 PROBNOT 1 1 NPS NPS 11344298 11344298 paper says nothing, PISA says monomer -- Annotation transfered from 1ie9 1ie9 PROBNOT 1 1 NPS NPS 11344298 11344298 paper says nothing, PISA says monomer 1iee NO 1 1 NPS NPS 11468395 11468395 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1iei NO 1 1 NPS NPS 11914486 11914486 SwissProt and PISA say monomer -- Annotation transfered from 1ads 1iel_1 PROBNOT 1 1 NPS NPS 11478888 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1iel_2 PROBNOT 1 1 NPS NPS 11478888 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1iem_1 PROBNOT 1 1 NPS NPS 11478888 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1iem_2 PROBNOT 1 1 NPS NPS 11478888 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1ier NO 24 24 Octa Octa 15299889 0 Interface geometry conserved with 1lb3 (80%) -- Annotation transfered from 1ies 1ies NO 24 24 Octa Octa 15299889 0 Interface geometry conserved with 1lb3 (80%) 1if2 NO 2 2 C2 C2 11589711 11589711 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1n55 1if4 PROBNOT 1 1 NPS NPS 0 0 9000633 says monomeric -- Annotation transfered from 1uga 1if5 PROBNOT 1 1 NPS NPS 0 0 9000633 says monomeric -- Annotation transfered from 1uga 1if6 PROBNOT 1 1 NPS NPS 0 0 9000633 says monomeric -- Annotation transfered from 1uga 1if7 PROBNOT 1 1 NPS NPS 11818565 11818565 9000633 says monomeric -- Annotation transfered from 1uga 1if8 PROBNOT 1 1 NPS NPS 11818565 11818565 9000633 says monomeric -- Annotation transfered from 1uga 1if9 PROBNOT 1 1 NPS NPS 11818565 11818565 9000633 says monomeric -- Annotation transfered from 1uga 1ifb NO 1 1 NPS NPS 2682622 2682622 Paper says: large quantities of the native, monomeric protein can be produced in, and readily purified, from Escherichia coli. -- Annotation transfered from 1icm 1ifc NO 1 1 NPS NPS 1740465 1740465 Paper says: large quantities of the native, monomeric protein can be produced in, and readily purified, from Escherichia coli. -- Annotation transfered from 1icm 1ifg NO 1 1 NPS NPS 11352586 11352586 This particular monomeric form was engineered - mEcotin was monomeric up to 1 mM as judged by gel filtration and analytical centrifugation. - interacts with chymotrypsin fold, very interesting protein to study interaction evolution 1ifs NO 2 2 C2 C2 7990130 7990130 Blocked ricin undergoes a pH-dependent reversible self-association, being predominantly dimeric at neutral pH and monomeric at acidic pH. -- Annotation transfered from 1uq5 1ift NO 2 2 C2 C2 7990130 7990130 Blocked ricin undergoes a pH-dependent reversible self-association, being predominantly dimeric at neutral pH and monomeric at acidic pH. -- Annotation transfered from 1uq5 1ifu NO 2 2 C2 C2 7990130 7990130 Blocked ricin undergoes a pH-dependent reversible self-association, being predominantly dimeric at neutral pH and monomeric at acidic pH. -- Annotation transfered from 1uq5 1ifv PROBYES 2 1 C2 NPS 12079359 12079359 Paper does not mention a dimer and PISA says monomer 1ig0 NO 2 2 C2 C2 11435118 11435118 Paper says that the active site is contributed by residues on both subunits 1ig1 PROBNOT 1 1 NPS NPS 11573098 11573098 Paper does not mention oligomer and PISa says monomer -- Annotation transfered from 1p4f 1ig5 NO 1 1 NPS NPS 9194174 9194174 Paper says monomer -- Annotation transfered from 3icb 1igb PROBYES 2 1 C2 NPS 8647077 8647077 Aminopeptidase from Aeromonas proteolytica (AAP) is a small, monomeric enzyme (32KDa) 1igd PROBYES 1 1 NPS NPS 7966308 7966308 12379842 implies it is monomeric, PISA also says monomeric -- Annotation transfered from 2igd 1igp NO 6 6 D3 D3 8034059 8034059 SP and EcoCyc say hexamer -- Annotation transfered from 1mjz 1igv NO 1 1 NPS NPS 9194174 9194174 Paper says monomer -- Annotation transfered from 3icb 1igw NO 4 4 D2 D2 11526312 11526312 Interface geometry conserved with 1s2u (27%) -- strange though: protein is much bigger! 1igx NO 2 2 C2 C2 11477109 11477109 -- Annotation transfered from 1cqe 1igz NO 2 2 C2 C2 11477109 11477109 -- Annotation transfered from 1cqe 1ihb PROBYES 2 1 NS NPS 9437433 9437433 1ihc NO 3 3 C3 C3 11325967 11325967 Interface geometry conserved with 1uux (52%) -- Annotation transfered from 1jlj 1ihi_1 PROBNOT 1 1 NPS NPS 11513593 12899831 Swissprot and PISA say it is a monomer - automatic transfer from 1mrq 1ihi_2 PROBNOT 1 1 NPS NPS 11513593 12899831 Swissprot and PISA say it is a monomer - automatic transfer from 1mrq 1ihk NO 2 2 C2 C2 11060292 11060292 Unlike most FGFs, FGF9 forms dimers in solution with a K(d) of 680 nm. - Monomer dimer equilibrium -- good paper to see techniques to characterize oligom. state. 1ihx NO 4 4 D2 D2 12136140 12136140 SP says homotetramer - papers too -- Annotation transfered from 1szj 1ihy NO 4 4 D2 D2 12136140 12136140 SP says homotetramer - papers too -- Annotation transfered from 1szj 1ihz NO 1 1 NPS NPS 15228960 15228960 Paper says monomeric -- Annotation transfered from 1ena 1ii2 PROBNOT 2 2 C2 C2 11700062 11700062 Paper says dimer - Interface geometry conserved with 1j3b (44%) -- good example for power of conservation in curation process. Also because PISA is wrong here 1ii3 NO 1 1 NPS NPS 15228960 15228960 Paper says monomeric -- Annotation transfered from 1ena 1ii5 NO 2 2 C2 C2 11518533 11518533 Forms dimers in solution, might also form tetramers (not seen here). Equilibrium centrifugation analysis revealed dimerization of the GluR0 ligand binding core with a dissociation constant of 0.8 μM. -- Annotation transfered from 1iit 1ii6 YES 2 1 C2 NPS 11328809 11328809 There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented 1iic_1 NO 1 1 NPS NPS 11371195 11371195 Paper says: This monomeric 455 residue enzyme has an ordered bi− bi reaction mechanism. Full characterization is in Towler, D.A. et al. Purification and characterization of myristoylCoA:protein N-myristoyltransferase. Proc. Natl. Acad. Sci. USA 84, 2708− 2712 (1987) (one of the rare case where PISA might be wrong while PDB is correct!) -- Annotation transfered from 1iid 1iic_2 NO 1 1 NPS NPS 11371195 11371195 Paper says: This monomeric 455 residue enzyme has an ordered bi− bi reaction mechanism. Full characterization is in Towler, D.A. et al. Purification and characterization of myristoylCoA:protein N-myristoyltransferase. Proc. Natl. Acad. Sci. USA 84, 2708− 2712 (1987) (one of the rare case where PISA might be wrong while PDB is correct!) -- Annotation transfered from 1iid 1iid NO 1 1 NPS NPS 11371195 11371195 Paper says: This monomeric 455 residue enzyme has an ordered bi− bi reaction mechanism. Full characterization is in Towler, D.A. et al. Purification and characterization of myristoylCoA:protein N-myristoyltransferase. Proc. Natl. Acad. Sci. USA 84, 2708− 2712 (1987) (one of the rare case where PISA might be wrong while PDB is correct!) 1iig PROBNOT 2 2 C2 C2 2062828 2062828 SP says dimer -- Annotation transfered from 6tim 1iih PROBNOT 2 2 C2 C2 2062828 2062828 SP says dimer -- Annotation transfered from 6tim 1iii NO 4 4 D2 D2 12403615 12403615 transthyretin is tetrameric -- Annotation transfered from 1fh2 1iik NO 4 4 D2 D2 12403615 12403615 transthyretin is tetrameric -- Annotation transfered from 1fh2 1iim NO 4 4 D2 D2 11373625 11373625 Interface geometry conserved with 1lvw (61%) 1iin NO 4 4 D2 D2 11373625 11373625 Interface geometry conserved with 1lvw (61%) -- Annotation transfered from 1iim 1iiq NO 2 2 C2 C2 11906284 11906284 -- Annotation transfered from 1ajx 1iit NO 2 2 C2 C2 11518533 11518533 Forms dimers in solution, might also form tetramers (not seen here). Equilibrium centrifugation analysis revealed dimerization of the GluR0 ligand binding core with a dissociation constant of 0.8 μM. 1iiu PROBNOT 1 1 NPS NPS 11738088 11738088 Serum retinol binding protein (RBP) is a monomeric protein of molecular weight 21,000 that transports vitamin A in the circulation (11604536) 1iiw NO 2 2 C2 C2 11518533 11518533 Forms dimers in solution, might also form tetramers (not seen here). Equilibrium centrifugation analysis revealed dimerization of the GluR0 ligand binding core with a dissociation constant of 0.8 μM. -- Annotation transfered from 1iit 1iiz PROBNOT 1 1 NPS NPS 11522783 11522783 1ij0 NO 3 3 C3 C3 11371197 11371197 Paper says trimer 1ij1 NO 3 3 C3 C3 11371197 11371197 Paper says trimer 1ij2 NO 3 3 C3 C3 11371197 11371197 Paper says trimer - Engineered Leucine Zipper protein GCN4 -- Annotation transfered from 1zij 1ij3 NO 3 3 C3 C3 11371197 11371197 Paper says trimer - Engineered Leucine Zipper protein GCN4 -- Annotation transfered from 1zij 1ij5 PROBNOT 1 1 NPS NPS 12517342 12517342 First, CBP40 does not have a fifth EF-hand (EF5), which packs together between two monomers and generates a dimer in the PEF family. - so apparently the dimerization part is missing -- interesting -- Annotation transfered from 1ij6 1ij6 PROBNOT 1 1 NPS NPS 12517342 12517342 First, CBP40 does not have a fifth EF-hand (EF5), which packs together between two monomers and generates a dimer in the PEF family. - so apparently the dimerization part is missing -- interesting 1ij8 NO 4 4 D2 D2 11395489 11395489 Avidin is a clear tetramer -- Annotation transfered from 2cam 1ij9 PROBNOT 1 1 NPS NPS 11679722 11679722 1iji NO 2 2 C2 C2 11518529 11518529 -- Annotation transfered from 1fg3 1ijj_1 PROBNOT 1 1 NPS NPS 11932258 11932258 BU changed since last release and is now corrected - Actin does not form closed dimer - automaticaly inferred from 1lcu 1ijj_2 PROBNOT 1 1 NPS NPS 11932258 11932258 BU changed since last release and is now corrected - Actin does not form closed dimer - automaticaly inferred from 1lcu 1ijl PROBYES 2 1 C2 NPS 11752784 11752784 Paper gives no real evidence for dimer formation and this class is not known to form dimers. In fact this QS is not found in other related proteins 1ijn NO 4 4 D2 D2 16185074 16185074 transthyretin is tetrameric -- Annotation transfered from 1fh2 1ijr PROBNOT 1 1 NPS NPS 11527723 11527723 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 -- Annotation transfered from 1lkk 1ijt PROBNOT 1 1 NPS NPS 11486033 11486033 Receptor dimerization is a prerequisite for FGF signaling and requires heparin or heparan sulfate proteoglycans - but no heparin is present here -- ligand induced dimerization 1ikg PROBNOT 1 1 NPS NPS 12215418 12215418 the Streptomyces R61 and Actinomadura R39 DD-peptidases, are water-soluble monomeric proteins; (12723972) -- Annotation transfered from 1pwd 1iki PROBNOT 1 1 NPS NPS 12215418 12215418 the Streptomyces R61 and Actinomadura R39 DD-peptidases, are water-soluble monomeric proteins; (12723972) -- Annotation transfered from 1pwd 1il2_1 YES 1 2 NPS C2 11566892 10562565 BU changed since last release and is now incorrect - Interface geometry conserved with 1g51 (48%) - automatic transfer from 1c0a 1il2_2 YES 1 2 NPS C2 11566892 10562565 BU changed since last release and is now incorrect - Interface geometry conserved with 1g51 (48%) - automatic transfer from 1c0a 1il3 PROBNOT 1 1 NPS NPS 11754581 11754581 Blocked ricin undergoes a pH-dependent reversible self-association, being predominantly dimeric at neutral pH and monomeric at acidic pH. -- Annotation transfered from 1apg 1il4 PROBNOT 1 1 NPS NPS 11754581 11754581 Blocked ricin undergoes a pH-dependent reversible self-association, being predominantly dimeric at neutral pH and monomeric at acidic pH. -- Annotation transfered from 1apg 1il9 PROBNOT 1 1 NPS NPS 11754581 11754581 Blocked ricin undergoes a pH-dependent reversible self-association, being predominantly dimeric at neutral pH and monomeric at acidic pH. -- Annotation transfered from 1apg 1ilr PROBYES 2 1 NS NPS 7867645 7867645 Paper says nothing, antagonist of a monomeric protein and PISA says monomer 1ils_1 PROBYES 2 1 C2 NPS 8568881 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 1ils_2 PROBYES 2 1 C2 NPS 8568881 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 1ilt_1 PROBNOT 1 1 NPS NPS 8175703 7867645 BU changed since last release and is now corrected - Paper says nothing, antagonist of a monomeric protein and PISA says monomer - automaticaly inferred from 1ilr 1ilt_2 PROBNOT 1 1 NPS NPS 8175703 7867645 BU changed since last release and is now corrected - Paper says nothing, antagonist of a monomeric protein and PISA says monomer - automaticaly inferred from 1ilr 1ilu_1 PROBNOT 1 1 NPS NPS 8568881 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1ilu_10 PROBNOT 1 1 NPS NPS 8568881 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1ilu_11 PROBNOT 1 1 NPS NPS 8568881 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1ilu_12 PROBNOT 1 1 NPS NPS 8568881 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1ilu_2 PROBNOT 1 1 NPS NPS 8568881 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1ilu_3 PROBNOT 1 1 NPS NPS 8568881 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1ilu_4 PROBNOT 1 1 NPS NPS 8568881 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1ilu_5 PROBNOT 1 1 NPS NPS 8568881 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1ilu_6 PROBNOT 1 1 NPS NPS 8568881 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1ilu_7 PROBNOT 1 1 NPS NPS 8568881 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1ilu_8 PROBNOT 1 1 NPS NPS 8568881 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1ilu_9 PROBNOT 1 1 NPS NPS 8568881 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1ilw PROBNOT 1 1 NPS NPS 11714269 11714269 PAper says nothing - PISA says monomer -- Annotation transfered from 1im5 1im2 PROBNOT 6 6 C6 C6 11468391 11468391 HSLU is the outer ring so it forms a hexamer (not a dodecamer) 1im5 PROBNOT 1 1 NPS NPS 11714269 11714269 PAper says nothing - PISA says monomer 1im6 PROBNOT 1 1 NPS NPS 12578370 12578370 EcoCyc & SP say monomer. -- Annotation transfered from 1eqm 1ima NO 2 2 C2 C2 8068620 8068620 - automatic transfer from 1imb 1imb NO 2 2 C2 C2 8068620 8068620 1imc NO 2 2 C2 C2 8068621 8068620 - automatic transfer from 1imb 1imd NO 2 2 C2 C2 8068621 8068620 - automatic transfer from 1imb 1ime NO 2 2 C2 C2 8068621 8068620 - automatic transfer from 1imb 1imf NO 2 2 C2 C2 8068621 8068620 - automatic transfer from 1imb 1imj PROBNOT 1 1 NPS NPS 14672934 14672934 Paper says nothing, PISA says monomer and related prots are monomeric 1imx PROBNOT 1 1 NPS NPS 11551198 11551198 Paper says: Both insulin and hIGF-I bind as monomers to their receptors and display an ability to bind to each others receptors - It says that hIGF-I does not assemble into hexamers -- Annotation transfered from 1gzr 1inc PROBNOT 1 1 NPS NPS 3430613 3430613 -- Annotation transfered from 1c1m 1ing PROBNOT 4 4 C4 C4 7650674 0 BU changed since last release and is now corrected - The paper does not describe the quaternary state. Comparision of the structure with 1ivd shows a very similar structure, and no ligand bound at the interface. So there is apparently no reason why the QS would differ. - automaticaly inferred from 1inw 1inh PROBNOT 4 4 C4 C4 7650674 0 BU changed since last release and is now corrected - The paper does not describe the quaternary state. Comparision of the structure with 1ivd shows a very similar structure, and no ligand bound at the interface. So there is apparently no reason why the QS would differ. - automaticaly inferred from 1inw 1ini NO 2 2 C2 C2 11427897 11427897 Paper says dimer: CDP-ME synthetase organizes as a homodimer with each subunit related by a crystallographic two-fold axis - SP says dimer too 1inj NO 2 2 C2 C2 11427897 11427897 Paper says dimer: CDP-ME synthetase organizes as a homodimer with each subunit related by a crystallographic two-fold axis - SP says dimer too -- Annotation transfered from 1ini 1inl NO 4 4 D2 D2 11731804 11731804 Interface geometry conserved with 1iy9 (45%) 1inn NO 2 2 C2 C2 11435117 11435117 -- Annotation transfered from 1vje 1ino NO 6 6 D3 D3 8034059 8034059 SP and EcoCyc say hexamer -- Annotation transfered from 1mjz 1inu NO 1 1 NPS NPS 11927576 11087397 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1inw PROBYES 1 4 NPS C4 7844831 0 The paper does not describe the quaternary state. Comparision of the structure with 1ivd shows a very similar structure, and no ligand bound at the interface. So there is apparently no reason why the QS would differ. 1inx PROBYES 1 4 NPS C4 7844831 0 The paper does not describe the quaternary state. Comparision of the structure with 1ivd shows a very similar structure, and no ligand bound at the interface. So there is apparently no reason why the QS would differ. - automatic transfer from 1inw 1io2 PROBNOT 1 1 NPS NPS 11274461 11274461 SP says monomer 1io3 PROBNOT 1 1 NPS NPS 11240122 11240122 -- Annotation transfered from 1co6 1iob PROBNOT 1 1 NPS NPS 1502561 0 SP says monomer - automatic transfer from 21bi 1ioc NO 1 1 NPS NPS 12359083 12359083 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ioe PROBNOT 2 2 NPS NPS 0 0 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1iof NO 4 4 D2 D2 11432786 11432786 Interface geometry conserved with 1a2z (50%) 1ioi NO 4 4 D2 D2 11432786 11432786 Interface geometry conserved with 1a2z (50%) -- Annotation transfered from 1iof 1iok YES 7 14 C7 D7 11563912 11563912 Paper says 14-mer 1iol NO 2 2 C2 C2 8756321 8756321 Paper says dimer -- Annotation transfered from 3dhe 1iom NO 2 2 C2 C2 0 0 Interface geometry conserved with 1a59 (41%) 1iop NO 1 1 NPS NPS 9548931 9548931 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1ioq NO 1 1 NPS NPS 11266617 11266617 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1ior NO 1 1 NPS NPS 11266617 11266617 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1ios NO 1 1 NPS NPS 11266617 11266617 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1iot NO 1 1 NPS NPS 11266617 11266617 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1iov YES 1 2 NPS C2 9054558 9054558 Interface geometry conseved with 1ehi (34%) -- Annotation transfered from 2dln 1iow YES 1 2 NPS C2 9054558 9054558 Interface geometry conseved with 1ehi (34%) -- Annotation transfered from 2dln 1ioz NO 1 1 NPS NPS 12836672 12836672 Ras proteins are monomeric G proteins -- Annotation transfered from 1ctq 1ip1 NO 1 1 NPS NPS 11599030 11599030 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ip2 NO 1 1 NPS NPS 11599030 11599030 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ip3_1 YES 1 2 NPS NPS 11599030 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 1ip3_2 YES 1 2 NPS NPS 11599030 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 1ip4 NO 1 1 NPS NPS 11599030 11599030 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ip5 NO 1 1 NPS NPS 11599030 11599030 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ip6 NO 1 1 NPS NPS 11599030 11599030 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ip7_1 YES 1 2 NPS NPS 11599030 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 1ip7_2 YES 1 2 NPS NPS 11599030 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 1ipe NO 2 2 C2 C2 12741812 12741812 paper says -- Annotation transfered from 2ae2 1ipf NO 2 2 C2 C2 12741812 12741812 paper says -- Annotation transfered from 2ae2 1ips NA 2 1 C2 NPS 7791906 7791906 Might be interesting to discuss in the paper - So the difference in the two crystallised forms is a combination of the crystallisation conditions and the conformational change upon substrate binding. Biological significance? Intuitively, I would say - probably none I hope this helps, Cheers, Pete 1ipw NO 6 6 D3 D3 8664256 8664256 SP and EcoCyc say hexamer -- Annotation transfered from 1mjz 1iq1 PROBNOT 1 1 NPS NPS 11448961 11448961 Paper says: suggesting that both proteins are monomeric under these conditions 1iq9 NA 1 1 NPS NPS 12538890 12538890 Ask the persons who work with it 1iqa PROBNOT 3 3 C3 C3 11733492 11733492 SP says trimer -- Annotation transfered from 1jtz 1iqe PROBNOT 2 2 NPS NPS 0 0 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1iqf PROBNOT 2 2 NPS NPS 0 0 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1iqg PROBNOT 2 2 NPS NPS 0 0 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1iqh PROBNOT 2 2 NPS NPS 0 0 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1iqi PROBNOT 2 2 NPS NPS 0 0 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1iqj PROBNOT 2 2 NPS NPS 0 0 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1iqk PROBNOT 2 2 NPS NPS 0 0 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1iql PROBNOT 2 2 NPS NPS 0 0 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1iqm PROBNOT 2 2 NPS NPS 0 0 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1iqn PROBNOT 2 2 NPS NPS 0 0 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1iqx NO 2 2 C2 C2 12537504 12537504 Interface geometry conserved with 1ksi (25%) -- Annotation transfered from 1sii 1iqy NO 2 2 C2 C2 12537504 12537504 Interface geometry conserved with 1ksi (25%) -- Annotation transfered from 1sii 1ir3 NA 2 1 C2 NPS 9312016 9312016 1ir7 NO 1 1 NPS NPS 11477222 11477222 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1ir8 NO 1 1 NPS NPS 11477222 11477222 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1ir9 NO 1 1 NPS NPS 11477222 11477222 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1ira PROBNOT 2 2 NPS NPS 9062194 9062194 Paper says: interleukin-1 receptor complexed with interleukin-1beta 1irb PROBYES 2 1 C2 NPS 8810924 8810924 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1bpq 1irc NO 1 1 NPS NPS 8204590 7579651 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1iri_1 NO 2 2 C2 C2 12054796 11371164 - automatic transfer from 1iat 1iri_2 NO 2 2 C2 C2 12054796 11371164 - automatic transfer from 1iat 1irk PROBNOT 1 1 NPS NPS 7997262 7997262 -- Annotation transfered from 1gag 1irn PROBYES 3 1 C3 NPS 8799113 8799113 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1iro 1iro PROBYES 3 1 C3 NPS 8799113 8799113 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes 1irv PROBNOT 1 1 NPS NPS 8718869 8718869 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1crh 1irw PROBNOT 1 1 NPS NPS 8718869 8718869 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1crh 1is0_1 PROBNOT 1 1 NPS NPS 11782172 6254988 BU changed since last release and is now corrected - In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution - automaticaly inferred from 1a07 1is0_2 PROBNOT 1 1 NPS NPS 11782172 6254988 BU changed since last release and is now corrected - In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution - automaticaly inferred from 1a07 1is3 NO 2 2 C2 C2 12206768 12206768 Paper says dimer -- Annotation transfered from 1is6 1is4 NO 2 2 C2 C2 12206768 12206768 Paper says dimer -- Annotation transfered from 1is6 1is5 NO 2 2 C2 C2 12206768 12206768 Paper says dimer -- Annotation transfered from 1is6 1is6 NO 2 2 C2 C2 12206768 12206768 Paper says dimer 1isa NO 2 2 C2 C2 7849024 7849024 Paper says dimer -- Annotation transfered from 1isc 1isb NO 2 2 C2 C2 7849024 7849024 Paper says dimer -- Annotation transfered from 1isc 1isc NO 2 2 C2 C2 7849024 7849024 Paper says dimer 1isn PROBNOT 1 1 NPS NPS 11756419 11856822 BU changed since last release and is now corrected - No info in paper - PISA says monomer - automaticaly inferred from 1h4r 1isp PROBNOT 1 1 NPS NPS 12077437 12077437 PISA says monomer and related proteins are monomeric 1isq NO 3 3 C3 C3 12296822 12296822 -- Annotation transfered from 1ge8 1ist_1 NA 1 1 NPS NPS 0 0 There is no paper and no info. PISA says monomer. -- Annotation transfered from 1vdn 1ist_2 NA 1 1 NPS NPS 0 0 There is no paper and no info. PISA says monomer. -- Annotation transfered from 1vdn 1isu PROBYES 2 1 C2 NPS 1453470 1453470 Paper says: it is assumed that this HiPIP functions as a monomer in solution 1itb PROBNOT 2 2 NPS NPS 9062193 9062193 Paper says: interleukin-1 receptor complexed with interleukin-1beta 1itg NO 2 2 C2 C2 7801124 7801124 Often described as a dimer (sometimes tetramer), and convincingly a similar dimer (same interface) is found in 1a5v (30% id). 1ith NO 4 4 D2 D2 1515107 1515107 SP says tetramer, paper too 1ito NO 1 1 NPS NPS 12044902 12044902 SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) 1itv PROBYES 2 1 C2 NPS 12126625 12126625 SP says: Exists as monomer, disulfide-linked homodimer - here, no S-S bond 1iu1_1 NO 1 1 NPS NPS 12042876 12176391 BU changed since last release and is now corrected - AP1 is tetrameric, this is one domain of one subunit which shoichiometry in the complex is one. - automatic transfer from 1gyw_2 1iu1_2 NO 1 1 NPS NPS 12042876 12176391 BU changed since last release and is now corrected - AP1 is tetrameric, this is one domain of one subunit which shoichiometry in the complex is one. - automatic transfer from 1gyw_2 1iu5 PROBNOT 1 1 NPS NPS 15272158 15272158 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes 1iu7 NO 2 2 C2 C2 12537504 12537504 Interface geometry conserved with 1ksi (25%) -- Annotation transfered from 1sii 1iu8 YES 2 4 C2 D2 12836705 12836705 Tetramer has interfaces geometries conserved with 1a2z (55%) 1iua PROBNOT 1 1 NPS NPS 12077426 12077426 The protein seem to be in a monomer dimer equilibrium (12077426 EPR and NMR studies have shown that HiPIPs might dimerize in the solution through their hydrophobic surfaces, a discovery that has led to important insights regarding the electron-transfer pathway) 1iug NO 2 2 C2 C2 15103612 0 Same interface but half size even though it is a thermophile! - interesting 1iuj NO 2 2 C2 C2 15103643 15103643 Interface geometry conserved with 1tz0 (32%) 1iun NO 2 2 C2 C2 12192074 12192074 The ß8 strands of both of the subunits form an antiparallel ß-sheet, and this tight interaction seems to be responsible for the dimeric structure of CumD in solution (Saku et al. 2002) -- Annotation transfered from 1iup 1iuo NO 2 2 C2 C2 12192074 12192074 The ß8 strands of both of the subunits form an antiparallel ß-sheet, and this tight interaction seems to be responsible for the dimeric structure of CumD in solution (Saku et al. 2002) -- Annotation transfered from 1iup 1iup NO 2 2 C2 C2 12192074 12192074 The ß8 strands of both of the subunits form an antiparallel ß-sheet, and this tight interaction seems to be responsible for the dimeric structure of CumD in solution (Saku et al. 2002) 1ius NO 2 2 C2 C2 8555229 8555229 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1iut NO 2 2 C2 C2 8555229 8555229 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1iuu NO 2 2 C2 C2 8555229 8555229 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1iuv NO 2 2 C2 C2 8555229 8555229 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1iuw NO 2 2 C2 C2 8555229 8555229 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1iux NO 2 2 C2 C2 8555229 8555229 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1iuz PROBNOT 1 1 NPS NPS 9933621 9933621 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) 1iv8 PROBNOT 1 1 NPS NPS -1 0 No paper, PISA says monomer 1ivc PROBNOT 4 4 C4 C4 7880809 0 BU changed since last release and is now corrected - The paper does not describe the quaternary state. Comparision of the structure with 1ivd shows a very similar structure, and no ligand bound at the interface. So there is apparently no reason why the QS would differ. - automaticaly inferred from 1inw 1ivd PROBNOT 4 4 C4 C4 7880809 0 BU changed since last release and is now corrected - The paper does not describe the quaternary state. Comparision of the structure with 1ivd shows a very similar structure, and no ligand bound at the interface. So there is apparently no reason why the QS would differ. - automaticaly inferred from 1inw 1ive PROBNOT 4 4 C4 C4 7880809 0 BU changed since last release and is now corrected - The paper does not describe the quaternary state. Comparision of the structure with 1ivd shows a very similar structure, and no ligand bound at the interface. So there is apparently no reason why the QS would differ. - automaticaly inferred from 1inw 1ivf PROBNOT 4 4 C4 C4 7880809 0 BU changed since last release and is now corrected - The paper does not describe the quaternary state. Comparision of the structure with 1ivd shows a very similar structure, and no ligand bound at the interface. So there is apparently no reason why the QS would differ. - automaticaly inferred from 1inw 1ivg PROBNOT 4 4 C4 C4 7880809 0 BU changed since last release and is now corrected - The paper does not describe the quaternary state. Comparision of the structure with 1ivd shows a very similar structure, and no ligand bound at the interface. So there is apparently no reason why the QS would differ. - automaticaly inferred from 1inw 1ivl PROBNOT 2 2 C2 C2 8158652 8158652 Seems a classic head-to-tail binding but it is strange that the two mols are not symmetrical. 1ivp NO 2 2 C2 C2 8514751 8514751 -- Annotation transfered from 1hii 1ivq NO 2 2 C2 C2 8514751 8514751 -- Annotation transfered from 1hii 1ivr NO 2 2 C2 C2 8952476 8952476 Interface geometry conserved with 2ay6 (38%) 1ivu NO 2 2 C2 C2 12134140 12134140 Interface geometry conserved with 1ksi (25%) -- Annotation transfered from 1sii 1ivv NO 2 2 C2 C2 12134140 12134140 Interface geometry conserved with 1ksi (25%) -- Annotation transfered from 1sii 1ivw NO 2 2 C2 C2 12134140 12134140 Interface geometry conserved with 1ksi (25%) -- Annotation transfered from 1sii 1ivx NO 2 2 C2 C2 12134140 12134140 Interface geometry conserved with 1ksi (25%) -- Annotation transfered from 1sii 1ivy NO 2 2 C2 C2 8591035 8591035 Paper says: The crystal structure of the 108 kDa dimer of the precursor HPP has been elucidated by making extensive use of twofold density averaging. The monomer consists of a core domain and a cap domain. Comparison with the distantly related wheat serine carboxypeptidase dimer shows that the two subunits in the HPP dimer differ by 15 degrees in mutual orientation 1iw2 PROBNOT 1 1 NPS NPS 12033936 12033936 Heterocomplex but not homo apparently: C8 is disulfide-linked to a C8 subunit that is noncovalently associated with a C8 chain. -- Annotation transfered from 1lf7 1iw6 NO 3 3 C3 C3 12445782 12445782 SP says trimer -- Annotation transfered from 2brd 1iw8 NO 6 6 D3 D3 12200535 10835340 Paper says: The enzyme is a 150 kDa homohexamer. -- Annotation transfered from 1eoi 1iw9 NO 3 3 C3 C3 15328615 15328615 SP says trimer -- Annotation transfered from 2brd 1iwd PROBNOT 1 1 NPS NPS 12784208 12784208 Paper says nothing - Related to monomeric structures and PISA says monomeric 1iwi PROBNOT 1 1 NPS NPS 14661963 14661963 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1iwj PROBNOT 1 1 NPS NPS 14661963 14661963 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1iwk PROBNOT 1 1 NPS NPS 14661963 14661963 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1iwo YES 2 1 NS NPS 12167852 12167852 This is clearly a crystal contact 1iwq PROBNOT 1 1 NPS NPS 12577052 12577052 -- Annotation transfered from 3cln 1iwt NO 1 1 NPS NPS 12198298 12198298 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1iwu NO 1 1 NPS NPS 12198298 12198298 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1iwv NO 1 1 NPS NPS 12198298 12198298 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1iww NO 1 1 NPS NPS 12198298 12198298 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1iwx NO 1 1 NPS NPS 12198298 12198298 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1iwy NO 1 1 NPS NPS 12198298 12198298 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1iwz NO 1 1 NPS NPS 12198298 12198298 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ix0 NO 1 1 NPS NPS 12646687 12646687 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ix1 PROBYES 2 1 C2 NPS 15382235 15382235 Paper implies monomer - related protein are monomeric and PISa says monomer 1ix6 NO 2 2 C2 C2 12488449 12488449 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1ix7 NO 2 2 C2 C2 12488449 12488449 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1ix8 NO 2 2 C2 C2 12488449 12488449 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1ix9 NO 2 2 C2 C2 0 0 PAper, SP say dimer -- Annotation transfered from 1i0h 1ixb NO 2 2 C2 C2 0 0 PAper, SP say dimer -- Annotation transfered from 1i0h 1ixe_1 NO 2 2 C2 C2 0 0 Interface geometry conserved with 1a59 (41%) - automatic transfer from 1iom 1ixe_2 NO 2 2 C2 C2 0 0 Interface geometry conserved with 1a59 (41%) - automatic transfer from 1iom 1ixf NO 3 3 C3 C3 12445782 12445782 SP says trimer -- Annotation transfered from 2brd 1ixk PROBNOT 1 1 NPS NPS 14997580 14997580 Paper says nothing, PISA says monomer 1ixl YES 1 2 NPS C2 14997554 14997554 Paper says dimer 1ixr PROBNOT 12 8 D2 D2 12408833 12408833 Paper says octameric - some domains are missing, this is why only a D2 symmetry is found and not a D4 1ixy_1 PROBNOT 1 1 NPS NPS 12445783 8062817 SP says monomer - automatic transfer from 1bgt 1ixy_2 PROBNOT 1 1 NPS NPS 12445783 8062817 SP says monomer - automatic transfer from 1bgt 1ixz YES 1 6 NPS C6 12377127 12377127 Paper says hexamer -- PISA does not find it 1iy0 YES 1 6 NPS C6 12377127 12377127 Paper says hexamer -- PISA does not find it -- Annotation transfered from 1ixz 1iy1 YES 1 6 NPS C6 12377127 12377127 Paper says hexamer -- PISA does not find it -- Annotation transfered from 1ixz 1iy2 YES 1 6 NPS C6 12377127 12377127 Paper says hexamer -- PISA does not find it -- Annotation transfered from 1ixz 1iy9 NO 4 4 D2 D2 0 0 Interface geometry conserved with 1uir (34%) 1iyb YES 2 1 C2 NPS 12484757 12484757 Since ryRNase NW appeared to be monomeric in solution, as judged by findings on the gel filtration column (data not shown), it is likely that the occurrence of molecules A and B in the asymmetric unit is due to a crystallographic artifact. 1iyd NO 6 6 D3 D3 12667063 12667063 Paper says hexamer - SP too 1iye NO 6 6 D3 D3 12667063 12667063 Paper says hexamer - SP too -- Annotation transfered from 1iyd 1iyk_1 PROBNOT 1 1 NPS NPS 12401496 9501915 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1nmt 1iyk_2 PROBNOT 1 1 NPS NPS 12401496 9501915 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1nmt 1iyl_1 PROBNOT 1 1 NPS NPS 12401496 9501915 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1nmt 1iyl_2 PROBNOT 1 1 NPS NPS 12401496 9501915 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1nmt 1iyl_3 PROBNOT 1 1 NPS NPS 12401496 9501915 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1nmt 1iyl_4 PROBNOT 1 1 NPS NPS 12401496 9501915 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1nmt 1iyo PROBNOT 1 1 NPS NPS 12221102 12221102 SP says monomer 1iyp PROBNOT 1 1 NPS NPS 12221102 12221102 SP says monomer -- Annotation transfered from 1iyo 1iyq PROBNOT 1 1 NPS NPS 12221102 12221102 SP says monomer -- Annotation transfered from 1iyo 1iys PROBNOT 1 1 NPS NPS 12962487 12962487 SP says monomer -- Annotation transfered from 1iyo 1iyz YES 2 2 C2 C2 12837796 12837796 Wrong dimer 1iz0 YES 1 1 NPS NPS 12837796 12837796 Dimer 1iz2 PROBNOT 1 1 NPS NPS 12244055 12244055 Paper says nothing, forms a heterodimer with an apparent 1:1 ratio (1oph) and PISA says monomer -- Annotation transfered from 1oo8 1iz3 NO 2 2 C2 C2 12482756 12482756 Paper says: Furthermore, the structure reveals the presence of a FIH-1 homodimer that forms in solution and is essential for FIH activity. 1iz4 YES 1 2 NPS C3 12649440 12649440 A mutation make it become a dimer 1iz5_1 YES 1 2 NPS C3 12649440 12649440 A mutation make it become a dimer - automatic transfer from 1iz4 1iz5_2 YES 1 2 NPS C3 12649440 12649440 A mutation make it become a dimer - automatic transfer from 1iz4 1iz7 NO 1 1 NPS NPS 12939138 12939138 SP says monomer -- Annotation transfered from 1g42 1iz8 NO 1 1 NPS NPS 12939138 12939138 SP says monomer -- Annotation transfered from 1g42 1iz9 PROBNOT 2 2 C2 C2 0 0 SP says dimer -- Annotation transfered from 1bmd 1izh NO 2 2 C2 C2 12460574 12460574 -- Annotation transfered from 1ajx 1izi NO 2 2 C2 C2 12460574 12460574 -- Annotation transfered from 1ajx 1izp NO 1 1 NPS NPS 12962489 12962489 -- Annotation transfered from 6rsa 1izq NO 1 1 NPS NPS 12962489 12962489 -- Annotation transfered from 6rsa 1izr NO 1 1 NPS NPS 12962489 12962489 -- Annotation transfered from 6rsa 1izy PROBNOT 2 2 C2 C2 12939276 12939276 It is a homodimer but it is strange to see that the dimerization mode seems different from the one in 1ons (different surface but similar orientation). Interesting to investigate 1izz PROBYES 1 2 NPS C2 12939276 12939276 1j01 PROBNOT 1 1 NPS NPS -1 0 Apparently the family doesnt form dimers but there is no clear evidence. -- Annotation transfered from 1exp 1j04 YES 1 1 NPS NPS 0 0 SP says homodimer + huge interface 1j06 NO 2 2 C2 C2 12505979 12505979 They explain in the paper why they observe a different crystal form without tetrameric assembly - interesting -- Annotation transfered from 1j07 1j07 NO 2 2 C2 C2 12505979 12505979 They explain in the paper why they observe a different crystal form without tetrameric assembly - interesting 1j0o PROBNOT 1 1 NPS NPS 14581238 14581238 Paper says nothing, PISA says monomer 1j0p PROBNOT 1 1 NPS NPS 14581238 14581238 Paper says nothing, PISA says monomer -- Annotation transfered from 1j0o 1j0x NO 4 4 D2 D2 14646080 14646080 SP says tetramer - papers too 1j14 PROBNOT 1 1 NPS NPS 12527302 12527302 Trypsin is monomeric -- Annotation transfered from 2trm 1j15 PROBNOT 1 1 NPS NPS 12527302 12527302 Trypsin is monomeric -- Annotation transfered from 2trm 1j16 PROBNOT 1 1 NPS NPS 12527302 12527302 Trypsin is monomeric -- Annotation transfered from 2trm 1j17 PROBNOT 1 1 NPS NPS 12527302 12527302 Trypsin is monomeric -- Annotation transfered from 2trm 1j19 PROBNOT 1 1 NPS NPS 12554651 12554651 May exist in equilibrium between monomers and oligomers: 10893267 - interesting -- Annotation transfered from 1gc7 1j1a PROBYES 2 1 C2 NPS 12616631 12616631 Human PLA predominantly exists as a monomer -- Annotation transfered from 1pod 1j1b NO 2 2 C2 C2 14993667 0 Paper says dimer detected in solution but the functional significance is unclear (autoinhibition is a possibility) - monomer/dimer equilibrium -- Annotation transfered from 1h8f 1j1c NO 2 2 C2 C2 14993667 0 Paper says dimer detected in solution but the functional significance is unclear (autoinhibition is a possibility) - monomer/dimer equilibrium -- Annotation transfered from 1h8f 1j1f PROBNOT 1 1 NPS NPS 12731868 12731868 No clear evidence was found. PISA says monomer -- Annotation transfered from 1uca 1j1g PROBNOT 1 1 NPS NPS 12731868 12731868 No clear evidence was found. PISA says monomer -- Annotation transfered from 1uca 1j1i NO 2 2 C2 C2 12659866 12659866 Paper says: gel filtration analysis showed that the native forms of the purified ht-CarCCA10 and ht-CarCJ3 were both dimers (molecular mass: approximately 70,000). 1j1m PROBNOT 1 1 NPS NPS 0 0 Blocked ricin undergoes a pH-dependent reversible self-association, being predominantly dimeric at neutral pH and monomeric at acidic pH. -- Annotation transfered from 1apg 1j1q PROBNOT 1 1 NPS NPS 0 0 PISA says monomeric -- Annotation transfered from 1gik 1j1r PROBNOT 1 1 NPS NPS 0 0 PISA says monomeric -- Annotation transfered from 1gik 1j1s PROBNOT 1 1 NPS NPS 0 0 PISA says monomeric -- Annotation transfered from 1gik 1j1y NO 4 4 D2 D2 16061252 16061252 Paper says tetramer 1j2e NO 2 2 C2 C2 12646248 0 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. -- Annotation transfered from 1tkr 1j2l PROBNOT 1 1 NPS NPS 14499613 14499613 Paper says nothing - PISA says monomer 1j2r NO 4 4 D2 D2 0 0 Interface geometry conserved with 1nba (24%) 1j2v PROBNOT 3 3 C3 C3 14706845 0 -- Annotation transfered from 1uku 1j2w NO 4 4 D2 D2 15388928 15388928 Paper says tetramer -- also unique arrangment? -- Annotation transfered from 1ub3 1j2y NO 12 12 Tetr Tetr 12784220 12784220 Interface geometry conserved with 1h0s (38%) 1j2z NO 3 3 C3 C3 14579368 14579368 Interface geometry conserved with 1lxa (43%) 1j32 NO 2 2 C2 C2 0 0 1j39 PROBNOT 1 1 NPS NPS 12860129 12860129 SP says monomer -- Annotation transfered from 1bgt 1j3b YES 2 2 NS C2 16239727 16239727 Paper says dimer - Interface geometry conserved with 1ii2 (44%) -- this version is wrong, but PISa gives the right one -- good example for power of conservation in curation process. 1j3f NO 1 1 NPS NPS 15869276 15869276 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1j3h_1 NO 1 1 NPS NPS 12614615 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 1j3h_2 NO 1 1 NPS NPS 12614615 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 1j3u NO 4 4 D2 D2 12706722 12706722 Interface geometry conserved with 1vdk (41%) 1j42 YES 1 2 NPS C2 12939276 12939276 Homodimeric -- Annotation transfered from 1ps4 1j49 NO 2 2 C2 C2 12054772 12054772 Interface geometry conserved with 2nad (28%) 1j4a_1 NO 2 2 C2 C2 12054772 12054772 Interface geometry conserved with 2nad (28%) - automatic transfer from 1j49 1j4a_2 NO 2 2 C2 C2 12054772 12054772 Interface geometry conserved with 2nad (28%) - automatic transfer from 1j49 1j4g_1 PROBNOT 1 1 NPS NPS 0 7619070 No info, PISA says monomer - automatic transfer from 1mrk 1j4g_2 PROBNOT 1 1 NPS NPS 0 7619070 No info, PISA says monomer - automatic transfer from 1mrk 1j4g_3 PROBNOT 1 1 NPS NPS 0 7619070 No info, PISA says monomer - automatic transfer from 1mrk 1j4g_4 PROBNOT 1 1 NPS NPS 0 7619070 No info, PISA says monomer - automatic transfer from 1mrk 1j4h NO 1 1 NPS NPS 14581219 14581219 Normally monomeric in solution - But very interesting: one mutation (F36M) transforms it into an inducible dimer. Isnt that so interesting? It thus also shows that it can be very simple to form a heterointerfaces, and that a high proportion of supposedly errors in the BU can reflect a potential high affinity (given that 1/2 mutations are introduced) - very nice example! -- Annotation transfered from 1fkh 1j4i NO 1 1 NPS NPS 14581219 14581219 Normally monomeric in solution - But very interesting: one mutation (F36M) transforms it into an inducible dimer. Isnt that so interesting? It thus also shows that it can be very simple to form a heterointerfaces, and that a high proportion of supposedly errors in the BU can reflect a potential high affinity (given that 1/2 mutations are introduced) - very nice example! -- Annotation transfered from 1fkh 1j4n NO 4 4 C4 C4 11780053 11780053 1j4r_1 PROBNOT 1 1 NPS NPS 11735566 10425089 BU changed since last release and is now corrected - - automaticaly inferred from 1qpl 1j4r_2 PROBNOT 1 1 NPS NPS 11735566 10425089 BU changed since last release and is now corrected - - automaticaly inferred from 1qpl 1j4r_3 PROBNOT 1 1 NPS NPS 11735566 10425089 BU changed since last release and is now corrected - - automaticaly inferred from 1qpl 1j4z NO 14 14 D7 D7 0 0 -- Annotation transfered from 1kp8 1j51_1 PROBNOT 1 1 NPS NPS 12114516 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1j51_2 PROBNOT 1 1 NPS NPS 12114516 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1j51_3 PROBNOT 1 1 NPS NPS 12114516 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1j51_4 PROBNOT 1 1 NPS NPS 12114516 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1j52 NO 1 1 NPS NPS 0 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1j55 NO 2 2 C2 C2 12507480 12507480 Paper says dimer 1j58 PROBNOT 6 6 D3 D3 12056897 12056897 Paper says hexamer - Interesting because it says that trimeric homologs also exist although they are not in PDB: The three proteins phaseolin, canavalin, and proglycinin are all classified as seed storage proteins. These seed storage proteins are trimeric bicupins with no metal binding sites but share some features of quaternary structure with the hexameric bicupin OXDC. -- SCOP dom_arch Error (2 doms) -- Annotation transfered from 1l3j 1j5p PROBNOT 2 2 C2 C2 0 0 No paper - PISA says dimer - Note similar structs have more subunits! 1j5x YES 1 2 NPS C2 0 0 Interface geometry conserved with 1jeo (25%) - A fene fusion event transformed the tetramer into a dimer. -- interesting for gene fusion and also for a case where thermophile has less subunits. 1j6v NO 2 2 C2 C2 11435117 11435117 -- Annotation transfered from 1vje 1j6w NO 2 2 C2 C2 11435117 11435117 1j6x NO 2 2 C2 C2 11435117 11435117 1j6z NO 1 1 NPS NPS 11474115 11474115 Actin exists in different states 1j74 PROBNOT 1 1 NPS NPS 11473255 11473255 Paper says: These structures reveal that the hMms2 monomer 1j7a PROBNOT 1 1 NPS NPS 9287153 9287153 Paper does not mention oligomer - similar proteins are monomeric -- Annotation transfered from 1j7c 1j7b PROBNOT 1 1 NPS NPS 9287153 9287153 Paper does not mention oligomer - similar proteins are monomeric -- Annotation transfered from 1j7c 1j7c PROBNOT 1 1 NPS NPS 9287153 9287153 Paper does not mention oligomer - similar proteins are monomeric 1j7n PROBYES 2 1 C2 NPS 11700563 11700563 Paper says nothing about the dimer - an email was sent to the authors -- And its a nature paper!!!! CRAP 1j8a PROBNOT 1 1 NPS NPS -1 0 -- Annotation transfered from 1az8 1j8f YES 3 1 NS NPS 11427894 11427894 This interaction within the crystal is unlikely to be biologically relevant (SIRT2 is a monomer in solution) 1j8q PROBNOT 1 1 NPS NPS 12351822 12351822 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1f4p 1j8t NO 2 2 C2 C2 11718561 11718561 Dimer because no tetramerization domain - SP is wrong (says dimer) -- Annotation transfered from 1j8u 1j8u NO 2 2 C2 C2 11718561 11718561 Dimer because no tetramerization domain - SP is wrong (says dimer) 1j91_1 NO 1 1 NPS NPS 11604527 11604527 Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. - automatic transfer from 1jam 1j91_2 NO 1 1 NPS NPS 11604527 11604527 Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. - automatic transfer from 1jam 1j93 NO 2 2 C2 C2 11524417 11524417 Interface geometry conserved with 1uro (35%) 1j96_1 PROBNOT 1 1 NPS NPS 11514561 12899831 Swissprot and PISA say it is a monomer - automatic transfer from 1mrq 1j96_2 PROBNOT 1 1 NPS NPS 11514561 12899831 Swissprot and PISA say it is a monomer - automatic transfer from 1mrq 1j98 NO 2 2 C2 C2 11601850 11601850 -- Annotation transfered from 1ie0 1j99 NA 1 1 NPS NPS 11988089 11988089 the active protein is a homodimer in solution but it might not form a dimer in the crystal 1j9e PROBNOT 1 1 NPS NPS 12351822 12351822 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1f4p 1j9g PROBNOT 1 1 NPS NPS 12351822 12351822 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1f4p 1j9m PROBNOT 1 1 NPS NPS 12627955 12627955 -- Annotation transfered from 1es2 1j9q NO 3 3 C3 C3 11478880 11478880 -- Annotation transfered from 1as7 1j9r NO 3 3 C3 C3 11478880 11478880 -- Annotation transfered from 1as7 1j9s NO 3 3 C3 C3 11478880 11478880 -- Annotation transfered from 1as7 1j9t NO 3 3 C3 C3 11478880 11478880 -- Annotation transfered from 1as7 1j9w_1 NO 1 1 NPS NPS 12009884 0 10529183 says monomer - automatic transfer from 1crm 1j9w_2 NO 1 1 NPS NPS 12009884 0 10529183 says monomer - automatic transfer from 1crm 1j9y PROBNOT 1 1 NPS NPS 11382747 11382747 Paper does not mention oligom. state - PISA says monomer 1ja3 PROBNOT 2 2 C2 C2 12096910 12096910 Paper says dimer 1ja8 NO 4 4 D2 D2 11580280 11580280 Paper says tetramer -- Annotation transfered from 1n0j 1ja9 NO 4 4 D2 D2 11467929 11467929 paper says tetramer 1jaf PROBYES 4 2 C2 C2 -1 0 1jah PROBYES 2 1 C2 NPS 9102473 9102473 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 1jai PROBYES 2 1 C2 NPS 9102473 9102473 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 1jam NO 1 1 NPS NPS 11604527 11604527 Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. 1jan PROBNOT 1 1 NPS NPS 8307185 8307185 No clear evidence after a quick search but PISA agrees ... -- Annotation transfered from 1a85 1jao PROBNOT 1 1 NPS NPS 7737183 7737183 No clear evidence after a quick search but PISA agrees ... -- Annotation transfered from 1a85 1jap PROBNOT 1 1 NPS NPS 8137810 8137810 No clear evidence after a quick search but PISA agrees ... -- Annotation transfered from 1a85 1jaq PROBNOT 1 1 NPS NPS 7737183 7737183 No clear evidence after a quick search but PISA agrees ... -- Annotation transfered from 1a85 1jaw YES 1 4 NPS D2 9520390 9520390 Paper says tetramer 1jb2 NO 2 2 C2 C2 11846560 11846560 NTF2 eluted with an apparent Mr of 31 kDa consistent with its existing in solution as dimers. -- Annotation transfered from 1oun 1jb4 NO 2 2 C2 C2 11846560 11846560 NTF2 eluted with an apparent Mr of 31 kDa consistent with its existing in solution as dimers. -- Annotation transfered from 1oun 1jb5 NO 2 2 C2 C2 11846560 11846560 NTF2 eluted with an apparent Mr of 31 kDa consistent with its existing in solution as dimers. -- Annotation transfered from 1oun 1jbb_1 PROBNOT 1 1 NPS NPS 11440714 11440714 The homomeric state is correct but this structure has been solved as a heterodimer 1jbc NO 4 4 D2 D2 15299577 0 SP says tetramer -- Annotation transfered from 1cjp 1jbe NO 1 1 NPS NPS 11410584 11410584 CheY is a Mr 14,000 monomeric protein -- Annotation transfered from 1chn 1jbk PROBNOT 1 1 NPS NPS 12054807 12054807 Paper says: ClpB forms a ring-shaped structure in the presence of nucleotides by self-oligomerization while the ring-shaped structure dissociates in the absence of nucleotides as observed by gel-filtration, chemical cross-linking and cryo EM experiments - nucleotide induced hexamerization 1jbm NO 7 7 C7 C7 12649441 12649441 Interface conserved with 1n9s (38% id) 1jbp NO 1 1 NPS NPS 8003955 8003955 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1jby NO 1 1 NPS NPS 12501176 12501176 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1jbz NO 1 1 NPS NPS 12501176 12501176 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1jc0_1 PROBNOT 1 1 NPS NPS 14722062 9145105 BU changed since last release and is now corrected - - automaticaly inferred from 1emc 1jc0_2 PROBNOT 1 1 NPS NPS 14722062 9145105 BU changed since last release and is now corrected - - automaticaly inferred from 1emc 1jc0_3 PROBNOT 1 1 NPS NPS 14722062 9145105 BU changed since last release and is now corrected - - automaticaly inferred from 1emc 1jc1_1 PROBNOT 1 1 NPS NPS 14722062 9145105 BU changed since last release and is now corrected - - automaticaly inferred from 1emc 1jc1_2 PROBNOT 1 1 NPS NPS 14722062 9145105 BU changed since last release and is now corrected - - automaticaly inferred from 1emc 1jc1_3 PROBNOT 1 1 NPS NPS 14722062 9145105 BU changed since last release and is now corrected - - automaticaly inferred from 1emc 1jci PROBNOT 1 1 NPS NPS 11851415 11851415 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1jcj_1 PROBYES 1 2 NPS C2 11598300 0 BU changed since last release and is now incorrect - Interface geometry somewhat conserved with 1mzh (32%) -- interesting: first case that I see where the place of the interaction is conserved but interface has completely changed - automaticaly inferred from 1ktn 1jcj_2 PROBYES 1 2 NPS C2 11598300 0 BU changed since last release and is now incorrect - Interface geometry somewhat conserved with 1mzh (32%) -- interesting: first case that I see where the place of the interaction is conserved but interface has completely changed - automaticaly inferred from 1ktn 1jcl_1 PROBYES 1 2 NPS C2 11598300 0 BU changed since last release and is now incorrect - Interface geometry somewhat conserved with 1mzh (32%) -- interesting: first case that I see where the place of the interaction is conserved but interface has completely changed - automaticaly inferred from 1ktn 1jcl_2 PROBYES 1 2 NPS C2 11598300 0 BU changed since last release and is now incorrect - Interface geometry somewhat conserved with 1mzh (32%) -- interesting: first case that I see where the place of the interaction is conserved but interface has completely changed - automaticaly inferred from 1ktn 1jct_1 PROBYES 4 4 NS D2 11513584 10769114 BU changed since last release and is now incorrect - Paper says tetramer, EcoCyc is wrong - automaticaly inferred from 1ec8 1jct_2 PROBYES 4 4 NS D2 11513584 10769114 BU changed since last release and is now incorrect - Paper says tetramer, EcoCyc is wrong - automaticaly inferred from 1ec8 1jcv NO 2 2 C2 C2 8652572 8652572 SOD is a dimer -- Annotation transfered from 2jcw 1jcx NO 4 4 D2 D2 11747443 11747443 Paper says tetramer -- Annotation transfered from 1fws 1jcy NO 4 4 D2 D2 11747443 11747443 Paper says tetramer -- Annotation transfered from 1fws 1jcz NO 2 2 C2 C2 11493685 11493685 Paper says dimer 1jd0 NO 2 2 C2 C2 11493685 11493685 Paper says dimer -- Annotation transfered from 1jcz 1jd1_1 NO 3 3 C3 C3 12112709 12112709 Interface conserved with 2csl (50% seq id) 1jd1_2 NO 3 3 C3 C3 12112709 12112709 Interface conserved with 2csl (50% seq id) -- Annotation transfered from 1jd1_1 1jd4_1 PROBNOT 1 1 NPS NPS 11511363 11511363 Gel filtration mentioned but apparently no dimer seen. - automatic transfer from 1jd6 1jd4_2 PROBNOT 1 1 NPS NPS 11511363 11511363 Gel filtration mentioned but apparently no dimer seen. - automatic transfer from 1jd6 1jd5 PROBNOT 1 1 NPS NPS 11511363 11511363 Gel filtration mentioned but apparently no dimer seen. -- Annotation transfered from 1jd6 1jd6 PROBNOT 1 1 NPS NPS 11511363 11511363 Gel filtration mentioned but apparently no dimer seen. 1jda PROBNOT 1 1 NPS NPS 9281429 9281429 SP says monomer -- Annotation transfered from 1gcy 1jdb PROBNOT 8 8 D2 D2 10089390 11551199 Carbamoyl phosphate synthetase (CPS) from Escherichia coli is allosterically regulated by the metabolites ornithine, IMP, and UMP. Ornithine and IMP function as activators, whereas UMP is an inhibitor. CPS undergoes changes in the state of oligomerization that are dependent on the protein concentration and the binding of allosteric effectors. Ornithine and IMP promote the formation of an (ab)4 tetramer while UMP favors the formation of an (ab)2 dimer. Propagate to all (CPS) please! -) -- Annotation transfered from 1bxr 1jdc PROBNOT 1 1 NPS NPS 9281429 9281429 SP says monomer -- Annotation transfered from 1gcy 1jdd PROBNOT 1 1 NPS NPS 9281429 9281429 SP says monomer -- Annotation transfered from 1gcy 1jde YES 2 2 C2 C2 11468288 11468288 Dimer but wrong interface, the right form is found in 1dik -- problem is PISA does not give the right one -- Annotation transfered from 2dik 1jdf_1 PROBYES 2 4 C2 D2 11513584 10769114 BU changed since last release and is now incorrect - Paper says tetramer, EcoCyc is wrong - automaticaly inferred from 1ec8 1jdf_2 PROBYES 2 4 C2 D2 11513584 10769114 BU changed since last release and is now incorrect - Paper says tetramer, EcoCyc is wrong - automaticaly inferred from 1ec8 1jdo NO 1 1 NPS NPS 9533619 9533619 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1jdr PROBNOT 1 1 NPS NPS 10220341 10220341 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1jds NO 6 6 D3 D3 11489901 11489901 Interface geometry conserved with 1q1g (27%) -- Annotation transfered from 1jdu 1jdt NO 6 6 D3 D3 11489901 11489901 Interface geometry conserved with 1q1g (27%) -- Annotation transfered from 1jdu 1jdu NO 6 6 D3 D3 11489901 11489901 Interface geometry conserved with 1q1g (27%) 1jdv NO 6 6 D3 D3 11489901 11489901 Interface geometry conserved with 1q1g (27%) -- Annotation transfered from 1jdu 1jdw NO 2 2 C2 C2 9218780 9218780 Paper says: The sedimentation analysis shows that AT and its mutants ATDelta M302 and ATDelta 11, as well as StrB1, form homodimers and that the mutations did not affect dimerization. -- Annotation transfered from 2jdw 1jdx YES 2 2 NS C2 9915841 9915841 Paper says: The sedimentation analysis shows that AT and its mutants ATDelta M302 and ATDelta 11, as well as StrB1, form homodimers and that the mutations did not affect dimerization. 1jdz NO 6 6 D3 D3 11489901 11489901 Interface geometry conserved with 1q1g (27%) -- Annotation transfered from 1jdu 1je0 NO 6 6 D3 D3 11489901 11489901 Interface geometry conserved with 1q1g (27%) -- Annotation transfered from 1jdu 1je1 NO 6 6 D3 D3 11489901 11489901 Interface geometry conserved with 1q1g (27%) -- Annotation transfered from 1jdu 1jea NO 1 1 NPS NPS 10493860 10493860 -- Annotation transfered from 1c9n 1jef NO 1 1 NPS NPS 15299852 0 -- Annotation transfered from 135l 1jeh NO 2 2 C2 C2 9538259 9538259 SP says dimer 1jej PROBNOT 1 1 NPS NPS 11493010 11493010 SP says monomer -- Annotation transfered from 1bgt 1jeo YES 1 4 NPS D2 11839305 11839305 Interface geometry conserved with 1viv (39%) 1jer PROBYES 2 1 C2 NPS 8931136 8931136 Paper says: cucumber stellacyanin is assumed to exist as a monomer in solution - However the dimer is an attractive model for e- transfer from what I understood -- I guess that these proteins are in a monomer dimer equilibrium, but that the equilibrium is shifted towards monomers. 1jez NO 2 2 C2 C2 12102621 12102621 Forms a dimer, paper interesting regarding the evolution of oligomeric state - good candidate 1jf0 PROBNOT 1 1 NPS NPS 0 0 No paper but related prots are monomeric and PISA says monomer 1jf2 PROBNOT 1 1 NPS NPS 12755603 12755603 Paper does not mention a dimer - PISA says monomer 1jf3 NO 1 1 NPS NPS 12211015 12211015 Paper says monomer -- Annotation transfered from 1jl7 1jf4 NO 1 1 NPS NPS 12211015 12211015 Paper says monomeric -- Annotation transfered from 1jl6 1jf7_1 PROBNOT 1 1 NPS NPS 11806712 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1jf7_2 PROBNOT 1 1 NPS NPS 11806712 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1jf9 NO 2 2 C2 C2 11827487 11827487 -- Annotation transfered from 1i29 1jfb PROBNOT 1 1 NPS NPS 11752781 11752781 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer -- Annotation transfered from 1cmj 1jfc PROBNOT 1 1 NPS NPS 11752781 11752781 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer -- Annotation transfered from 1cmj 1jfd NO 6 6 D3 D3 9237692 9237692 SP and EcoCyc say hexamer -- Annotation transfered from 1mjz 1jfx PROBNOT 1 1 NPS NPS 11427528 11427528 Paper says nothing - PISA says monomeric 1jg0 NO 2 2 C2 C2 11590022 11590022 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1jg1 PROBNOT 1 1 NPS NPS 11700066 11700066 Lacks the dimerization domain found in 1fbn & 1g8s - PISA says monomer - interesting case 1jg2 PROBNOT 1 1 NPS NPS 11700066 11700066 Lacks the dimerization domain found in 1fbn & 1g8s - PISa says monomer -- Annotation transfered from 1jg1 1jg3_1 PROBNOT 1 1 NPS NPS 11700066 11700066 Lacks the dimerization domain found in 1fbn & 1g8s - PISA says monomer - interesting case - automatic transfer from 1jg1 1jg3_2 PROBNOT 1 1 NPS NPS 11700066 11700066 Lacks the dimerization domain found in 1fbn & 1g8s - PISA says monomer - interesting case - automatic transfer from 1jg1 1jg4 PROBNOT 1 1 NPS NPS 11700066 11700066 Lacks the dimerization domain found in 1fbn & 1g8s - PISa says monomer -- Annotation transfered from 1jg1 1jg6 PROBNOT 1 1 NPS NPS 11493010 11493010 SP says monomer -- Annotation transfered from 1bgt 1jg7 PROBNOT 1 1 NPS NPS 11493010 11493010 SP says monomer -- Annotation transfered from 1bgt 1jg8 NO 4 4 D2 D2 0 0 -- Annotation transfered from 1m6s 1jg9 NO 1 1 NPS NPS 11467966 11467966 9882648 says: Under both native and denaturing conditions, the molecular mass obtained was 70 ± 2 kDa (Fig. 3B). This result demonstrates the monomeric structure of the amylosucrase from N. polysaccharea -- Annotation transfered from 1mw1 1jgc NO 24 24 Octa Octa 11752777 11752777 Interface geometry conserved with 1bfr (49%) 1jgi NO 1 1 NPS NPS 11467966 11467966 9882648 says: Under both native and denaturing conditions, the molecular mass obtained was 70 ± 2 kDa (Fig. 3B). This result demonstrates the monomeric structure of the amylosucrase from N. polysaccharea -- Annotation transfered from 1mw1 1jgj PROBNOT 1 1 NPS NPS 11452084 11452084 No trimeric packing -- Annotation transfered from 1h68 1jh1 PROBNOT 1 1 NPS NPS 11563922 11563922 No clear evidence after a quick search but PISA agrees ... -- Annotation transfered from 1a85 1jh5 YES 10 60 NS Icos 11853672 11853672 The virus-like assembly was also detected in solution using gel filtration and electron microscopy. -- very nice example of C3 --> Icosah 1jhd NO 2 2 C2 C2 11724564 11724564 Paper says: the native Riftia enzyme is a dimer with 396 residues/subunit 1jhg NO 2 2 C2 C2 -1 0 1jhj PROBNOT 1 1 NPS NPS 11524682 11524682 Paper says nothing and 1gqp was shown to be monomeric, PISA says monomer too 1jhz NO 2 2 C2 C2 11781089 11781089 EcoCyc says homodimer 1ji0 PROBNOT 1 1 NPS NPS 0 0 Nucleotide present but PISA does not find a dimer. 1ji3 PROBYES 2 1 NS NPS 12417199 12417199 Paper does not mention oligm. Since it is a thermostable protein, I really doubt that it is open. 1ji4 NO 12 12 Tetr Tetr 12368104 12368104 Interface geometry conserved with 1o9r (28%) 1ji5 NO 12 12 Tetr Tetr 11836250 11836250 Interface geometry conserved with 1o9r (26%) 1ji7 PROBNOT 3 3 NS NS 11483520 11483520 Paper says: Here we show that the TEL-SAM domain forms a helical, head-to-tail polymeric structure 1jia PROBYES 2 2 NS C2 9761847 9761847 Paper says dimer, not sure of they mean symmetrical one but I am almost entirely sure they do (I havent seen a non sym. one in the whole family) 1jig NO 12 12 Tetr Tetr 11836250 11836250 Interface geometry conserved with 1o9r (25%) 1jim PROBNOT 1 1 NPS NPS -1 0 -- Annotation transfered from 1c1m 1jin PROBNOT 1 1 NPS NPS 11469860 11469860 Paper does not mention oligomer - PISA says monomer - many instances of monomers -- Annotation transfered from 1egy 1jio PROBNOT 1 1 NPS NPS 11469860 11469860 Paper does not mention oligomer - PISA says monomer - many instances of monomers -- Annotation transfered from 1egy 1jip PROBNOT 1 1 NPS NPS 11469860 11469860 Paper does not mention oligomer - PISA says monomer - many instances of monomers -- Annotation transfered from 1egy 1jiq_1 NO 2 2 C2 C2 12054796 11371164 - automatic transfer from 1iat 1jiq_2 NO 2 2 C2 C2 12054796 11371164 - automatic transfer from 1iat 1jir PROBNOT 1 1 NPS NPS 0 0 -- Annotation transfered from 1az8 1jis NO 1 1 NPS NPS 11679726 11679726 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1jit NO 1 1 NPS NPS 11679726 11679726 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1jiu PROBNOT 1 1 NPS NPS 11493010 11493010 SP says monomer -- Annotation transfered from 1bgt 1jiv PROBNOT 1 1 NPS NPS 11493010 11493010 SP says monomer -- Annotation transfered from 1bgt 1jix PROBNOT 1 1 NPS NPS 11493010 11493010 SP says monomer -- Annotation transfered from 1bgt 1jiy NO 1 1 NPS NPS 11679726 11679726 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1jj0 NO 1 1 NPS NPS 11679726 11679726 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1jj1 NO 1 1 NPS NPS 11679726 11679726 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1jj3_1 NO 1 1 NPS NPS 11679726 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1jj3_2 NO 1 1 NPS NPS 11679726 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1jj7 NO 1 1 NPS NPS 11532960 11532960 SP and paper says: Heterodimer of TAP1 and TAP2. 1jj9 PROBNOT 1 1 NPS NPS 11278347 11278347 No clear evidence after a quick search but PISA agrees ... -- Annotation transfered from 1a85 1jjb PROBNOT 1 1 NPS NPS 12095250 12095250 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1jje_1 PROBNOT 1 1 NPS NPS 11390410 10757977 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Paper says nothing - PISA implies monomer - automaticaly inferred from 1ddk 1jje_2 PROBNOT 1 1 NPS NPS 11390410 10757977 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Paper says nothing - PISA implies monomer - automaticaly inferred from 1ddk 1jjf PROBNOT 1 1 NPS NPS 11601976 11601976 Paper says nothing, PISA says monomer -- Annotation transfered from 1jt2 1jjt_1 PROBNOT 1 1 NPS NPS 11390410 10757977 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Paper says nothing - PISA implies monomer - automaticaly inferred from 1ddk 1jjt_2 PROBNOT 1 1 NPS NPS 11390410 10757977 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Paper says nothing - PISA implies monomer - automaticaly inferred from 1ddk 1jjv PROBNOT 1 1 NPS NPS 11886213 11886213 Paper says nothing, PISA says monomer 1jjw YES 12 12 D2 D6 11717526 11717526 BU changed since last release and is now incorrect - 1jk9_1 NO 2 2 NPS NPS 11524675 11524675 This is the biological assembly and the heterodimer dominates the homodimer 1jk9_2 NO 2 2 NPS NPS 11524675 11524675 This is the biological assembly and the heterodimer dominates the homodimer -- Annotation transfered from 1jk9_1 1jka NO 1 1 NPS NPS 9041653 9041653 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1jkb NO 1 1 NPS NPS 9041653 9041653 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1jkc NO 1 1 NPS NPS 9041653 9041653 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1jkd NO 1 1 NPS NPS 9041653 9041653 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1jkf NO 4 4 D2 D2 11779862 11779862 MIP synthase is a homotetramer both in solution and in the solid state -- Annotation transfered from 1jki 1jki NO 4 4 D2 D2 11779862 11779862 MIP synthase is a homotetramer both in solution and in the solid state 1jkk PROBNOT 1 1 NPS NPS 11573098 11573098 Paper does not mention oligomer and PISa says monomer -- Annotation transfered from 1p4f 1jkl PROBNOT 1 1 NPS NPS 11573098 11573098 Paper does not mention oligomer and PISa says monomer -- Annotation transfered from 1p4f 1jkm YES 4 2 C2 C2 10201402 10201402 Paper says: We have carried out gel filtration experiments (data not shown) and confirmed that the protein is dimeric in solution. 1jks PROBNOT 1 1 NPS NPS 11573098 11573098 Paper does not mention oligomer and PISa says monomer -- Annotation transfered from 1p4f 1jkt_1 PROBNOT 1 1 NPS NPS 11573098 14505650 Paper does not mention oligomer and PISa says monomer - automatic transfer from 1p4f 1jkt_2 PROBNOT 1 1 NPS NPS 11573098 14505650 Paper does not mention oligomer and PISa says monomer - automatic transfer from 1p4f 1jkx_1 PROBYES 2 1 C2 NPS 11695901 10606510 9698564 says: E. coli GarTfase exhibits a pH-dependent monomer-dimer equilibrium with the monomer preferably populated above pH 7.4 and the dimer below pH 6.6 -- pH induced dimerization -- this interface is too weak - automatic transfer from 1c2t 1jkx_2 PROBYES 2 1 NS NPS 11695901 10606510 BU changed since last release and is now incorrect - 9698564 says: E. coli GarTfase exhibits a pH-dependent monomer-dimer equilibrium with the monomer preferably populated above pH 7.4 and the dimer below pH 6.6 -- pH induced dimerization -- this interface is too weak - automaticaly inferred from 1c2t 1jky PROBNOT 1 1 NPS NPS 11700563 11700563 Paper says nothing about a dimer - an email was sent to the authors -- And its a nature paper!!!! CRAP 1jl1 PROBNOT 1 1 NPS NPS 11734003 11734003 SP says monomer -- Annotation transfered from 1f21 1jl2 PROBYES 4 1 NS NPS 11790848 11790848 Paper does not mention an oligomer - PISA says monomer 1jl5 PROBYES 4 1 D2 NPS 11575934 11575934 Paper says: The biological significance of the YopM tetramer is unclear at the present time. Although it occurs in all of the crystal forms of the protein and seems artfully designed, we cannot rule out the possibility that the tetramer is an artifact resulting from the high concentration of calcium in crystallization solutions. Experiments designed to demonstrate oligomerization under more physiological conditions produced contradictory results: size-exclusion chromatography coupled with refractive index/light-scattering measurements indicated that the protein is monomeric in both the absence and presence of 0.8 mM calcium ions 1jl6 NO 1 1 NPS NPS 12211015 12211015 Paper says monomeric 1jl7 NO 1 1 NPS NPS 12211015 12211015 Paper says monomer 1jl9 PROBNOT 2 2 C2 C2 11438527 11438527 Paper says: Crystal structure of human epidermal growth factor and its dimerization 1jld NO 2 2 C2 C2 9216835 9216835 -- Annotation transfered from 1hii 1jlh_1 NO 2 2 C2 C2 12573240 11371164 - automatic transfer from 1iat 1jlh_2 NO 2 2 C2 C2 12573240 11371164 - automatic transfer from 1iat 1jlj NO 3 3 C3 C3 11554796 11554796 Interface geometry conserved with 1uux (52%) 1jlm PROBNOT 1 1 NPS NPS 8747460 8747460 -- Annotation transfered from 1ido 1jln NO 1 1 NPS NPS 11493009 11493009 Thus, in solution PTP-SL/BR7 has an apparent molecular mass of approximately 31 kDa, 1jlr NO 4 4 D2 D2 11773618 11773618 Interface geometry conserved with 1o5o (40%) -- very interesting: GDP binds and contact three subunits, this stabilizes the complexe and activity increases by 6 folds! 1jls NO 4 4 D2 D2 11773618 11773618 Interface geometry conserved with 1o5o (40%) -- Annotation transfered from 1jlr 1jlu NO 1 1 NPS NPS 8003955 8003955 two alpha, two beta, alphas do not contact each others 1jlw NO 2 2 C2 C2 11604524 11604524 Interface geometry conserved with 1e6b (27%) 1jm0_1 PROBNOT 2 2 C2 C2 11749531 0 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Four helix bundle -- Check symmetry search - automaticaly inferred from 1ovu 1jm0_2 PROBNOT 2 2 C2 C2 11749531 0 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Four helix bundle -- Check symmetry search - automaticaly inferred from 1ovu 1jm0_3 PROBNOT 2 2 C2 C2 11749531 0 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Four helix bundle -- Check symmetry search - automaticaly inferred from 1ovu 1jm6 NO 2 2 C2 C2 11483605 11483605 Paper says: Biochemical evidence suggests that PDK2 is a dimer - Interface conserved with 1gjv (36%) 1jmb_1 PROBNOT 2 2 C2 C2 11749531 0 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Four helix bundle -- Check symmetry search - automaticaly inferred from 1ovu 1jmb_2 PROBNOT 2 2 C2 C2 11749531 0 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Four helix bundle -- Check symmetry search - automaticaly inferred from 1ovu 1jmc PROBNOT 1 1 NPS NPS 8990123 8990123 Human RPA is a heterotrimer with three subunits of ~70, 32 and 14 kDa, which are referred to as RPA70, RPA32 and RPA14, 1jme NA 2 1 C2 NPS 11695889 16214136 Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. 1jmf NO 2 2 C2 C2 9514716 9514716 SP says homodimer -- Annotation transfered from 4tms 1jmg NO 2 2 C2 C2 9514716 9514716 SP says homodimer -- Annotation transfered from 4tms 1jmh NO 2 2 C2 C2 9514716 9514716 SP says homodimer -- Annotation transfered from 4tms 1jmi NO 2 2 C2 C2 9514716 9514716 SP says homodimer -- Annotation transfered from 4tms 1jmj PROBYES 2 1 C2 NPS 12169660 12169660 Paper implies monomer - PISA says monomer 1jml PROBNOT 1 1 NPS NPS 11526208 11526208 1k51 implies this ones correct 1jmo PROBYES 3 1 NPS NPS 12169660 12169660 BU changed since last release and is now incorrect - Paper implies monomer - PISA says monomer 1jmw YES 1 2 NPS C2 11504940 11504940 dimeric -- Annotation transfered from 1was 1jmy PROBNOT 1 1 NPS NPS 11563913 11563913 Paper says nothing, PISA says monomer -- Annotation transfered from 1f6w 1jn2 YES 1 4 NPS D2 11504727 11504727 1jn4_1 PROBNOT 1 1 NPS NPS 11513604 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1jn4_2 PROBNOT 1 1 NPS NPS 11513604 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1jnd PROBNOT 1 1 NPS NPS 11821393 11821393 Paper does not mention dimer, PISA says monomer -- Annotation transfered from 1jne 1jne PROBNOT 1 1 NPS NPS 11821393 11821393 Paper does not mention dimer, PISA says monomer 1jnk PROBNOT 1 1 NPS NPS 9739089 9739089 -- Annotation transfered from 1pmv 1jnp YES 2 2 NS C2 11679718 11679718 INterface geometry conserved with 1jsg (56%) - Paper says: Solution studies have shown that hTcl1 and mTcl1 form dimers, whereas hMtcp1 exists primarily as a monomer. -- interestingly, the two dimers have the same interaction geometry while the third even thought it forms a dimer in the crystal, has a different geometry 1jo8 PROBNOT 1 1 NPS NPS 11668184 11668184 Paper says nothing, PISA says monomeric, SH3 domains are functional as monomers 1joa YES 1 4 NPS D2 8756456 8756456 Paper says it is tetrameric 1joi PROBNOT 1 1 NPS NPS 8109977 8109977 Azurin is monomeric (cf.5azu) 1joj_1 PROBNOT 4 4 D2 D2 11580281 0 BU changed since last release and is now corrected - - automaticaly inferred from 1qgl 1joj_2 PROBNOT 4 4 D2 D2 11580281 0 BU changed since last release and is now corrected - - automaticaly inferred from 1qgl 1jol PROBYES 2 1 C2 NPS 8679526 8679526 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1dds 1jom PROBNOT 1 1 NPS NPS 8679526 8679526 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1jp6 NO 1 1 NPS NPS 11796110 11796110 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1jp7 NO 6 6 D3 D3 11489901 11489901 Interface geometry conserved with 1q1g (27%) -- Annotation transfered from 1jdu 1jp8 NO 1 1 NPS NPS 11796110 11796110 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1jp9 NO 1 1 NPS NPS 11796110 11796110 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1jpb NO 1 1 NPS NPS 11796110 11796110 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1jpd NO 1 1 NPS NPS 11747448 11747448 Paper says monomer in solution 1jph NO 2 2 C2 C2 11719352 11719352 Interface geometry conserved with 1j93 (35%) -- Annotation transfered from 1uro 1jpi NO 2 2 C2 C2 11719352 11719352 Interface geometry conserved with 1j93 (35%) -- Annotation transfered from 1uro 1jpk NO 2 2 C2 C2 11719352 11719352 Interface geometry conserved with 1j93 (35%) -- Annotation transfered from 1uro 1jpm PROBYES 4 8 NS D4 11747448 11747448 Paper says octamer 1jpo NO 1 1 NPS NPS -1 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1jpu NO 8 8 D4 D4 11566129 11566129 Interface geometry conserved with 1kq3 (48%) -- Annotation transfered from 1jq5 1jpv NO 6 6 D3 D3 11489901 11489901 Interface geometry conserved with 1q1g (27%) -- Annotation transfered from 1jdu 1jpz_1 NA 1 1 NPS NPS 11695892 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1jpz_2 NA 1 1 NPS NPS 11695892 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1jq3 NO 4 4 D2 D2 11731804 11731804 Interface geometry conserved with 1iy9 (45%) -- Annotation transfered from 1inl 1jq5 NO 8 8 D4 D4 11566129 11566129 Interface geometry conserved with 1kq3 (48%) 1jq8_1 PROBNOT 1 1 NPS NPS 12351825 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 1jq8_2 PROBNOT 1 1 NPS NPS 12351825 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 1jq9_1 PROBNOT 1 1 NPS NPS 12186870 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 1jq9_2 PROBNOT 1 1 NPS NPS 12186870 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 1jqa NO 8 8 D4 D4 11566129 11566129 Interface geometry conserved with 1kq3 (48%) -- Annotation transfered from 1jq5 1jqb NO 4 4 D2 D2 12381840 12381840 1jqh_1 PROBNOT 1 1 NPS NPS 11591350 11694888 Fragment - Paper says: The IGF1 receptor is structurally homologous to the insulin receptor. Members of this receptor subfamily are heterotetrameric glycoproteins consisting of two extracellular ligand-binding alpha-subunits and two transmembrane catalytic beta-subunits. No dimer mentioned and PISA says monomer - automatic transfer from 1k3a 1jqh_2 PROBNOT 1 1 NPS NPS 11591350 11694888 Fragment - Paper says: The IGF1 receptor is structurally homologous to the insulin receptor. Members of this receptor subfamily are heterotetrameric glycoproteins consisting of two extracellular ligand-binding alpha-subunits and two transmembrane catalytic beta-subunits. No dimer mentioned and PISA says monomer - automatic transfer from 1k3a 1jqh_3 PROBNOT 1 1 NPS NPS 11591350 11694888 Fragment - Paper says: The IGF1 receptor is structurally homologous to the insulin receptor. Members of this receptor subfamily are heterotetrameric glycoproteins consisting of two extracellular ligand-binding alpha-subunits and two transmembrane catalytic beta-subunits. No dimer mentioned and PISA says monomer - automatic transfer from 1k3a 1jqn YES 4 4 NS D2 12467579 12467579 Interface geometry conserved with 1jqo (40%) -- Annotation transfered from 1qb4 1jqo NO 4 4 D2 D2 12467579 12467579 Interface geometry conserved with 1jqn (40%) 1jqq NA 4 1 C2 NPS 12453410 12453410 Paper says nothing, related proteins are monomers but PISA says tetramer 1jqu_1 NO 1 1 NPS NPS 11847274 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1jqu_2 NO 1 1 NPS NPS 11847274 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1jqu_3 NO 1 1 NPS NPS 11847274 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1jqu_4 NO 1 1 NPS NPS 11847274 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1jqv NO 2 2 C2 C2 12732650 12732650 -- Annotation transfered from 1jub 1jqw NO 2 2 C2 C2 11601850 11601850 -- Annotation transfered from 1ie0 1jqx NO 2 2 C2 C2 12732650 12732650 -- Annotation transfered from 1jub 1jqz_1 PROBNOT 1 1 NPS NPS 11714927 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jqz_2 PROBNOT 1 1 NPS NPS 11714927 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jr9 NO 2 2 C2 C2 12054740 12054740 Iron- or manganese-dependent SODs exist as dimers or tetramers in solution with dimers as functional units. It is said that this one has a hogh tendency to dissociate into monomers. 1jrb NO 2 2 C2 C2 12732650 12732650 -- Annotation transfered from 1jub 1jrc NO 2 2 C2 C2 12732650 12732650 -- Annotation transfered from 1jub 1jre NO 12 12 Tetr Tetr 0 0 Interface geometry conserved with 1o9r (55%) -- Annotation transfered from 1dps 1jri_1 NO 7 7 C7 C7 12649441 12649441 Interface conserved with 1n9s (38% id) -- Annotation transfered from 1jbm 1jri_2 NO 7 7 C7 C7 12649441 12649441 Interface conserved with 1n9s (38% id) -- Annotation transfered from 1jbm 1jrk_1 NO 2 2 C2 C2 11914479 11914479 Paper says dimer - automatic transfer from 1k26 1jrk_2 NO 2 2 C2 C2 11914479 11914479 Paper says dimer - automatic transfer from 1k26 1jrr PROBNOT 1 1 NPS NPS 11546761 11546761 Paper says nothing, PISA says monomer 1jrs PROBNOT 1 1 NPS NPS 8845765 8845765 -- Annotation transfered from 1az8 1jrt PROBNOT 1 1 NPS NPS 8845765 8845765 -- Annotation transfered from 1az8 1jrx_1 PROBNOT 1 1 NPS NPS 11591148 10581550 SP says monomer - automatic transfer from 1qjd 1jrx_2 PROBNOT 1 1 NPS NPS 11591148 10581550 SP says monomer - automatic transfer from 1qjd 1jry_1 PROBNOT 1 1 NPS NPS 11591148 10581550 SP says monomer - automatic transfer from 1qjd 1jry_2 PROBNOT 1 1 NPS NPS 11591148 10581550 SP says monomer - automatic transfer from 1qjd 1jrz_1 PROBNOT 1 1 NPS NPS 11591148 10581550 SP says monomer - automatic transfer from 1qjd 1jrz_2 PROBNOT 1 1 NPS NPS 11591148 10581550 SP says monomer - automatic transfer from 1qjd 1js0 NO 3 3 C3 C3 11790847 11790847 Yet another form (fourth) of the RNAse 1js1 PROBNOT 3 3 C3 C3 12095263 12095263 Paper says trimer 1js2 YES 4 1 NS NPS 11802718 11802718 The protein seem to be in a monomer dimer equilibrium (12077426 EPR and NMR studies have shown that HiPIPs might dimerize in the solution through their hydrophobic surfaces, a discovery that has led to important insights regarding the electron-transfer pathway) 1jsc NO 2 2 C2 C2 11902841 11902841 Paper says dimer -- interesting: the paper implies that it is closer to tetrameric enzymes of this family rather than to a dimeric one - nice for evolution study 1jse NO 1 1 NPS NPS 9517539 9517539 -- Annotation transfered from 135l 1jsf NO 1 1 NPS NPS 9517539 9517539 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1jsg NO 2 2 C2 C2 9519406 9519406 Interface geometry conserved with 1jnp (56%) 1jsv NO 1 1 NPS NPS 11604388 11604388 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1jsw NO 4 4 D2 D2 9230045 9230045 Interface geometry conserved with 1vdk (42%) 1jsz PROBNOT 1 1 NPS NPS 12056899 12056899 SP and PISA say monomer -- Annotation transfered from 1eam 1jt2 PROBNOT 1 1 NPS NPS 11601976 11601976 Paper says nothing, PISA says monomer 1jt3_1 PROBNOT 1 1 NPS NPS 11714927 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jt3_2 PROBNOT 1 1 NPS NPS 11714927 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jt4_1 PROBNOT 1 1 NPS NPS 11714927 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jt4_2 PROBNOT 1 1 NPS NPS 11714927 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jt5_1 PROBNOT 1 1 NPS NPS 11714927 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jt5_2 PROBNOT 1 1 NPS NPS 11714927 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jt7_1 PROBNOT 1 1 NPS NPS 11714927 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jt7_2 PROBNOT 1 1 NPS NPS 11714927 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jt7_3 PROBNOT 1 1 NPS NPS 11714927 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jt7_4 PROBNOT 1 1 NPS NPS 11714927 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jt9 NO 6 6 D3 D3 12051945 12051945 SP and EcoCyc say hexamer. -- Annotation transfered from 1cd5 1jtc_1 PROBNOT 1 1 NPS NPS 11714927 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jtc_2 PROBNOT 1 1 NPS NPS 11714927 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jtc_3 PROBNOT 1 1 NPS NPS 11714927 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jtc_4 PROBNOT 1 1 NPS NPS 11714927 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jte PROBNOT 1 1 NPS NPS 12056899 12056899 SP and PISA say monomer -- Annotation transfered from 1eam 1jtf PROBNOT 1 1 NPS NPS 12056899 12056899 SP and PISA say monomer -- Annotation transfered from 1eam 1jtm NO 1 1 NPS NPS 11884133 11884133 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1jtn_1 NO 1 1 NPS NPS 11884133 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1jtn_2 NO 1 1 NPS NPS 11884133 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1jtq NO 2 2 C2 C2 11697906 11697906 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1jts_1 PROBNOT 12 12 Tetr Tetr 0 0 BU changed since last release and is now corrected - Interface geometry conserved with 1o9r (55%) - automaticaly inferred from 1f33 1jts_2 PROBNOT 12 12 Tetr Tetr 0 0 BU changed since last release and is now corrected - Interface geometry conserved with 1o9r (55%) - automaticaly inferred from 1f33 1jtu NO 2 2 C2 C2 11697906 11697906 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1jtv NO 2 2 C2 C2 12490543 12490543 Paper says dimer -- Annotation transfered from 3dhe 1jtz PROBNOT 3 3 C3 C3 11581298 11581298 SP says trimer 1ju6_1 NO 2 2 C2 C2 11697906 11278511 SP says dimer - automatic transfer from 1hw4 1ju6_2 NO 2 2 C2 C2 11697906 11278511 SP says dimer - automatic transfer from 1hw4 1ju9 NO 2 2 C2 C2 11601993 11601993 -- Annotation transfered from 8adh 1jub NO 2 2 C2 C2 12732650 12732650 1jue NO 2 2 C2 C2 12732650 12732650 -- Annotation transfered from 1jub 1jug NO 1 1 NPS NPS 15299900 0 1juh YES 4 2 NS C2 11839311 11839311 Paper says dimer: At functionally relevant pH values (pH 5.0–7.0), 2,3QD is a homodimer of about 100 kDa, containing not, vert, similar25% (w/w) of N-linked glycan chains. 1jui_1 PROBNOT 4 4 D2 D2 11371463 0 BU changed since last release and is now corrected - - automaticaly inferred from 1qgl 1jui_2 PROBNOT 4 4 D2 D2 11371463 0 BU changed since last release and is now corrected - - automaticaly inferred from 1qgl 1juj_1 NO 2 2 C2 C2 11697906 11278511 SP says dimer - automatic transfer from 1hw4 1juj_2 NO 2 2 C2 C2 11697906 11278511 SP says dimer - automatic transfer from 1hw4 1juo NO 2 2 C2 C2 11714909 11714909 1jut NO 2 2 C2 C2 11697906 11697906 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1juv PROBYES 2 1 C2 NPS 0 0 No paper found, PISA says monomer and related proteins are monomeric 1jv0_1 NO 1 1 NPS NPS 12009884 0 10529183 says monomer - automatic transfer from 1crm 1jv0_2 NO 1 1 NPS NPS 12009884 0 10529183 says monomer - automatic transfer from 1crm 1jv4 PROBNOT 1 1 NPS NPS 11717500 11717500 Gel filtration performed and no dimer or oligomer mentioned. -- Annotation transfered from 1i06 1jv6 PROBNOT 1 1 NPS NPS 11676543 11676543 PISA does not find the trimer so the trimeric contacts probably do not exist. -- Annotation transfered from 1brd 1jv7 PROBNOT 1 1 NPS NPS 11676543 11676543 PISA does not find the trimer so the trimeric contacts probably do not exist. -- Annotation transfered from 1brd 1jva_1 PROBNOT 1 1 NPS NPS 11884132 10601013 BU changed since last release and is now corrected - From the paper it seems to be a monomer. - automaticaly inferred from 1ef0 1jva_2 PROBNOT 1 1 NPS NPS 11884132 10601013 BU changed since last release and is now corrected - From the paper it seems to be a monomer. - automaticaly inferred from 1ef0 1jvb NO 4 4 D2 D2 12051852 12051852 SP says homodimer and homotetramer - equilibium? -- Annotation transfered from 1r37 1jvi NO 2 2 C2 C2 11601850 11601850 -- Annotation transfered from 1ie0 1jvj PROBNOT 1 1 NPS NPS 11870868 11870868 EcoCyc says monomer -- Annotation transfered from 1jwp 1jvk NO 2 2 C2 C2 11976493 11976493 1jvl PROBYES 2 1 C2 NPS 11740504 11740504 This is hard to believe but it seems that azurin is a monomeric protein! -- Annotation transfered from 1bex 1jvo_1 PROBYES 4 1 C2 NPS 11740504 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 1jvo_2 PROBYES 4 1 C2 NPS 11740504 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 1jvo_3 PROBYES 4 1 C2 NPS 11740504 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 1jvp NO 1 1 NPS NPS 11755359 11755359 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1jvq PROBNOT 2 2 C2 C2 15342247 15342247 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization 1jvt_1 PROBNOT 1 1 NPS NPS 11746706 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1jvt_2 PROBNOT 1 1 NPS NPS 11746706 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1jvu_1 PROBNOT 1 1 NPS NPS 11746706 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1jvu_2 PROBNOT 1 1 NPS NPS 11746706 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1jvv_1 PROBNOT 1 1 NPS NPS 11746706 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1jvv_2 PROBNOT 1 1 NPS NPS 11746706 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1jvw NO 1 1 NPS NPS 11751578 11751578 Paper says it is monomeric - the dimeric protein 1f9d has a similar function (it induces the same effect) so good example to claim that oligomeric state can modulate the function but does not change it. - interesting 1jvx PROBNOT 1 1 NPS NPS 12538909 12538909 EcoCyc says monomer -- Annotation transfered from 1nl5 1jvy PROBNOT 1 1 NPS NPS 12538909 12538909 EcoCyc says monomer -- Annotation transfered from 1nl5 1jw4 PROBNOT 1 1 NPS NPS 11790091 11790091 EcoCyc says monomer -- Annotation transfered from 1nl5 1jw5 PROBNOT 1 1 NPS NPS 11790091 11790091 EcoCyc says monomer -- Annotation transfered from 1nl5 1jw6 NO 4 4 D2 D2 11732694 0 SP says tetramer -- Annotation transfered from 1cjp 1jw8 NO 1 1 NPS NPS 0 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1jwj_1 PROBYES 2 1 C2 NPS 11669619 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1jwj_2 PROBYES 2 1 C2 NPS 11669619 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1jwk_1 PROBYES 2 1 C2 NPS 11669619 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1jwk_2 PROBYES 2 1 C2 NPS 11669619 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1jwl_2 NO 2 2 C2 C2 11580238 11601849 Dimer because tetramerization helix is missing - automatic transfer from 1jyf 1jwn_1 NO 2 2 C2 C2 11732898 9826511 Paper and SP say dimer - automatic transfer from 7hbi 1jwn_2 NO 2 2 C2 C2 11732898 9826511 Paper and SP say dimer - automatic transfer from 7hbi 1jwo PROBNOT 1 1 NPS NPS 0 0 1jwp PROBNOT 1 1 NPS NPS 12079336 12079336 EcoCyc says monomer 1jwr NO 1 1 NPS NPS 12214315 12214315 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1jwt PROBNOT 1 1 NPS NPS 11720865 11720865 -- Annotation transfered from 1doj 1jwv PROBNOT 1 1 NPS NPS 12079336 12079336 EcoCyc says monomer -- Annotation transfered from 1jwp 1jwx NO 2 2 C2 C2 11959984 11959984 -- Annotation transfered from 1d6f 1jwz PROBNOT 1 1 NPS NPS 12079336 12079336 EcoCyc says monomer -- Annotation transfered from 1jwp 1jxb PROBNOT 1 1 NPS NPS 11847275 11847275 SP says monomer -- Annotation transfered from 1f21 1jxg_1 PROBNOT 1 1 NPS NPS 11679761 6698995 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) - automatic transfer from 2pcy 1jxg_2 PROBNOT 1 1 NPS NPS 11679761 6698995 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) - automatic transfer from 2pcy 1jxh NO 2 2 C2 C2 11839308 11839308 Interface geometry conserved with 1ub0 (53%) 1jxi NO 2 2 C2 C2 11839308 11839308 Interface geometry conserved with 1ub0 (53%) -- Annotation transfered from 1jxh 1jxn_1 NO 2 2 C2 C2 -1 11090284 paper says dimer - automatic transfer from 1fx5 1jxn_2 NO 2 2 C2 C2 -1 11090284 paper says dimer - automatic transfer from 1fx5 1jxt PROBNOT 1 1 NPS NPS 11572978 11572978 Although no clear reference was found, it is accepted to me that crambin is at least predominantly monomeric in somution. -- this family is a MESSSS -- Annotation transfered from 1cbn 1jxu PROBNOT 1 1 NPS NPS 11572978 11572978 Although no clear reference was found, it is accepted to me that crambin is at least predominantly monomeric in somution. -- this family is a MESSSS -- Annotation transfered from 1cbn 1jxv NO 6 6 D3 D3 11835509 11835509 Hexamer of two different chains: A and B (A6, A5B, A4B2, A3B3, A2B4, AB5, B6). - Interesting for Dmitry -- Annotation transfered from 1ucn 1jxw PROBNOT 1 1 NPS NPS 11572978 11572978 Although no clear reference was found, it is accepted to me that crambin is at least predominantly monomeric in somution. -- this family is a MESSSS -- Annotation transfered from 1cbn 1jxx PROBNOT 1 1 NPS NPS 11572978 11572978 Although no clear reference was found, it is accepted to me that crambin is at least predominantly monomeric in somution. -- this family is a MESSSS -- Annotation transfered from 1cbn 1jxy PROBNOT 1 1 NPS NPS 11572978 11572978 Although no clear reference was found, it is accepted to me that crambin is at least predominantly monomeric in somution. -- this family is a MESSSS -- Annotation transfered from 1cbn 1jxz PROBNOT 3 3 C3 C3 11695894 11695894 PISA says trimer so I ll rely on that - (paper says nothing) 1jy0_1 PROBNOT 1 1 NPS NPS 14627732 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jy0_2 PROBNOT 1 1 NPS NPS 14627732 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1jy1 PROBNOT 1 1 NPS NPS 11839309 11839309 Paper says monomer 1jyb NO 2 2 C2 C2 12459910 12459910 -- Annotation transfered from 1lkm 1jyc_1 PROBNOT 4 4 D2 D2 11371463 0 BU changed since last release and is now corrected - - automaticaly inferred from 1qgl 1jyc_2 PROBNOT 4 4 D2 D2 11371463 0 BU changed since last release and is now corrected - - automaticaly inferred from 1qgl 1jyd NO 1 1 NPS NPS 11604536 11604536 Serum retinol binding protein (RBP) is a monomeric protein of molecular weight 21,000 that transports vitamin A in the circulation 1jye NO 2 2 C2 C2 11601849 11601849 Dimer because tetramerization helix is missing -- Annotation transfered from 1jyf 1jyf NO 2 2 C2 C2 11601849 11601849 Dimer because tetramerization helix is missing 1jyi_1 PROBNOT 4 4 D2 D2 10821862 0 BU changed since last release and is now corrected - - automaticaly inferred from 1qgl 1jyi_2 PROBNOT 4 4 D2 D2 10821862 0 BU changed since last release and is now corrected - - automaticaly inferred from 1qgl 1jyj NO 1 1 NPS NPS 11604536 11604536 Serum retinol binding protein (RBP) is a monomeric protein of molecular weight 21,000 that transports vitamin A in the circulation -- Annotation transfered from 1jyd 1jyk PROBNOT 1 1 NPS NPS 11706035 11706035 Paper says: So far, dimerization of soluble α3GalT has not been reported; it has been proposed that different glycosyltransferases may form non-covalent oligomers during Golgi sorting/trafficking. It is conceivable that the homologous UDP-binding subdomain shared by Golgi glycosyltransferases of different specificities (see below) might support their non-covalent association, increasing their efficiency in glycan biosynthesis. -- Annotation transfered from 1g8o 1jyl YES 4 1 NS NPS 11706035 11706035 Paper says: The crystals of LicC·CDP-Cho·Mg2+ ternary complex contain four molecules in an asymetric unit, assembled to form two dimers. However, purified LicC behaves as a monomer 1jym PROBYES 10 1 C2 NPS 12005434 12005434 Paper says: For instance, size-exclusion chromatography on a Superdex 200 HR (Amersham-Pharmacia) column showed numerous peaks corresponding to aggregates containing from one to six PfPDF subunits. Also, dynamic light scattering experiments indicated a high molecular mass, which was hard to determine precisely due to the large polydispersity (data not shown). - Because it is difficult to know which aggregate is right, saying it is a monomer is safer -- monomer oligomer equilibrium 1jyq NO 2 2 C2 C2 11827484 11827484 domain swapped 1jyr NO 1 1 NPS NPS 11827484 11827484 -- Annotation transfered from 1zfp 1jys NO 2 2 C2 C2 11591349 11591349 Paper implies dimer - Dimer conserved with the dimer of the related hexameric form -- Annotation transfered from 1nc3 1jyu NO 1 1 NPS NPS 11827484 11827484 -- Annotation transfered from 1zfp 1jza_1 PROBNOT 1 1 NPS NPS 11847271 11847271 Paper says nothing and PISA says monomer - automatic transfer from 1jzb 1jza_2 PROBNOT 1 1 NPS NPS 11847271 11847271 Paper says nothing and PISA says monomer - automatic transfer from 1jzb 1jzb PROBNOT 1 1 NPS NPS 11847271 11847271 Paper says nothing and PISA says monomer 1jze PROBNOT 1 1 NPS NPS 11716717 11716717 This is hard to believe but it seems that azurin is a monomeric protein! -- Annotation transfered from 1azu 1jzf PROBNOT 1 1 NPS NPS 11716717 11716717 This is hard to believe but it seems that azurin is a monomeric protein! -- Annotation transfered from 1azu 1jzg PROBNOT 1 1 NPS NPS 11716717 11716717 This is hard to believe but it seems that azurin is a monomeric protein! -- Annotation transfered from 1azu 1jzh PROBNOT 1 1 NPS NPS 11716717 11716717 This is hard to believe but it seems that azurin is a monomeric protein! -- Annotation transfered from 1azu 1jzi_1 PROBNOT 1 1 NPS NPS 11716717 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1jzi_2 PROBNOT 1 1 NPS NPS 11716717 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1jzj_1 PROBNOT 1 1 NPS NPS 11716717 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1jzj_2 PROBNOT 1 1 NPS NPS 11716717 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1jzk_1 NO 2 2 C2 C2 11732898 9826511 Paper and SP say dimer - automatic transfer from 7hbi 1jzk_2 NO 2 2 C2 C2 11732898 9826511 Paper and SP say dimer - automatic transfer from 7hbi 1jzl NO 2 2 C2 C2 11732898 11732898 Paper and SP say dimer -- Annotation transfered from 7hbi 1jzm NO 2 2 C2 C2 11732898 11732898 Paper and SP say dimer -- Annotation transfered from 7hbi 1jzn NO 10 10 D5 D5 15049685 15049685 Consistent with the decamer seen in these two crystal forms, RSL was found to have a molecular mass of ~150 kDa as determined by gel filtration in the absence of Ca2+ - disulfide linked dimers -- Annotation transfered from 1muq 1jzr_1 NO 2 2 C2 C2 11695904 11171973 Interface geometry conserved with 1e6b (26%) - automatic transfer from 1hqo 1jzr_2 NO 2 2 C2 C2 11695904 11171973 Interface geometry conserved with 1e6b (26%) - automatic transfer from 1hqo 1k02 PROBYES 1 2 NPS C2 11668181 11668181 Paper says dimer -- Annotation transfered from 1bwl 1k03 PROBYES 1 2 NPS C2 11668181 11668181 Paper says dimer -- Annotation transfered from 1bwl 1k04 NO 2 2 C2 C2 12005431 12005431 Domain swapped dimer 1k05_1 YES 1 2 NPS C2 12005431 14527389 BU changed since last release and is now incorrect - Domain swapped dimer found here - automaticaly inferred from 1ow6 1k05_2 YES 1 2 NPS C2 12005431 14527389 BU changed since last release and is now incorrect - Domain swapped dimer found here - automaticaly inferred from 1ow6 1k05_3 YES 1 2 NPS C2 12005431 14527389 BU changed since last release and is now incorrect - Domain swapped dimer found here - automaticaly inferred from 1ow6 1k06 NO 2 2 C2 C2 11895439 11895439 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1k08 NO 2 2 C2 C2 11895439 11895439 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1k0a NO 2 2 C2 C2 11695904 11695904 Interface geometry conserved with 1e6b (26%) -- Annotation transfered from 1hqo 1k0b_1 NO 2 2 C2 C2 11695904 11171973 Interface geometry conserved with 1e6b (26%) - automatic transfer from 1hqo 1k0b_2 NO 2 2 C2 C2 11695904 11171973 Interface geometry conserved with 1e6b (26%) - automatic transfer from 1hqo 1k0c_1 NO 2 2 C2 C2 11695904 11171973 Interface geometry conserved with 1e6b (26%) - automatic transfer from 1hqo 1k0c_2 NO 2 2 C2 C2 11695904 11171973 Interface geometry conserved with 1e6b (26%) - automatic transfer from 1hqo 1k0d_1 NO 2 2 C2 C2 11695904 11171973 Interface geometry conserved with 1e6b (26%) - automatic transfer from 1hqo 1k0d_2 NO 2 2 C2 C2 11695904 11171973 Interface geometry conserved with 1e6b (26%) - automatic transfer from 1hqo 1k0i NO 2 2 C2 C2 11805318 11805318 the enzyme exists mainly as a dimer in solution -- But this interface is wrong - PISA finds the right one 1k0j NA 2 2 C2 C2 11805318 11805318 the enzyme exists mainly as a dimer in solution -- But this interface is wrong - PISA finds the right one - Even though this interface is weaker than the other one, it is interesting to note that its geometry is conserved with 1ojb (40% simil) - very interesting 1k0k PROBNOT 1 1 NPS NPS 0 0 SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio 1k0l NO 2 2 C2 C2 11805318 11805318 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1k0m_1 PROBYES 1 2 NPS C2 11551966 14613939 BU changed since last release and is now incorrect - - automaticaly inferred from 1rk4 1k0m_2 PROBYES 1 2 NPS C2 11551966 14613939 BU changed since last release and is now incorrect - - automaticaly inferred from 1rk4 1k0n_1 PROBYES 1 2 NPS C2 11551966 14613939 BU changed since last release and is now incorrect - - automaticaly inferred from 1rk4 1k0n_2 PROBYES 1 2 NPS C2 11551966 14613939 BU changed since last release and is now incorrect - - automaticaly inferred from 1rk4 1k0o_1 PROBYES 1 2 NPS C2 11551966 14613939 BU changed since last release and is now incorrect - - automaticaly inferred from 1rk4 1k0o_2 PROBYES 1 2 NPS C2 11551966 14613939 BU changed since last release and is now incorrect - - automaticaly inferred from 1rk4 1k0u_1 NO 4 4 D2 D2 11741948 10387078 SP says tetramer, interface geometry conserved among rat and human. - automatic transfer from 1b3r 1k0u_2 NO 4 4 D2 D2 11741948 10387078 SP says tetramer, interface geometry conserved among rat and human. - automatic transfer from 1b3r 1k1i PROBNOT 1 1 NPS NPS 11676542 11676542 -- Annotation transfered from 1az8 1k1j PROBNOT 1 1 NPS NPS 11676542 11676542 -- Annotation transfered from 1az8 1k1l PROBNOT 1 1 NPS NPS 11676542 11676542 -- Annotation transfered from 1az8 1k1m PROBNOT 1 1 NPS NPS 11676542 11676542 -- Annotation transfered from 1az8 1k1n PROBNOT 1 1 NPS NPS 11676542 11676542 -- Annotation transfered from 1az8 1k1o PROBNOT 1 1 NPS NPS 11676542 11676542 -- Annotation transfered from 1az8 1k1p PROBNOT 1 1 NPS NPS 11676542 11676542 -- Annotation transfered from 1az8 1k1t NO 2 2 C2 C2 12012342 12012342 -- Annotation transfered from 1ajx 1k1u NO 2 2 C2 C2 12012342 12012342 -- Annotation transfered from 1ajx 1k26 NO 2 2 C2 C2 11914479 11914479 Paper says dimer 1k27 NO 3 3 C3 C3 14705926 14705926 Interface conserved with 1v48 (27%) -- Annotation transfered from 1cg6 1k2a PROBNOT 1 1 NPS NPS 11916383 11916383 -- Annotation transfered from 1hi2 1k2b NO 2 2 C2 C2 12012342 12012342 -- Annotation transfered from 1ajx 1k2c NO 2 2 C2 C2 12012342 12012342 -- Annotation transfered from 1ajx 1k2e NO 2 2 C2 C2 11914479 11914479 Paper says dimer -- Annotation transfered from 1k26 1k2i NA 1 1 NPS NPS 11846564 3980476 They explain in the paper (3980476) that chymotrypsin can form an asymetric dimer, but can also be found as a monomer in particular conditions. Here PISA says monomer. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 1ex3 1k2o_1 PROBNOT 1 1 NPS NPS 11606730 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1k2o_2 PROBNOT 1 1 NPS NPS 11606730 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1k2p YES 2 1 C2 NPS 11527964 11527964 BTK-KD is packed in a dimeric form in the crystal lattice but is present mainly in monomeric form in solution 1k2r NO 2 2 C2 C2 0 0 Clear dimer -- Annotation transfered from 1m00 1k2s NO 2 2 C2 C2 0 0 Clear dimer -- Annotation transfered from 1m00 1k2t NO 2 2 C2 C2 0 0 Clear dimer -- Annotation transfered from 1m00 1k2u NO 2 2 C2 C2 0 0 Clear dimer -- Annotation transfered from 1m00 1k2w PROBYES 2 4 C2 D2 15805591 0 Paper says it could probably be a tetramer. SP would then be wrong (they say dimer) 1k38 NO 2 2 C2 C2 0 0 interface geometry conserved with 1h8z (37%) 1k39 NO 6 6 D3 D3 0 0 The variable mode of assembly of the trimeric disks of the crotonase superfamily - interesting -- Annotation transfered from 1pjh 1k3a PROBNOT 1 1 NPS NPS 11694888 11694888 Fragment - Paper says: The IGF1 receptor is structurally homologous to the insulin receptor. Members of this receptor subfamily are heterotetrameric glycoproteins consisting of two extracellular ligand-binding alpha-subunits and two transmembrane catalytic beta-subunits. No dimer mentioned and PISA says monomer 1k3c NO 1 1 NPS NPS 11724534 11724534 Paper says: E. coli PCK is a monomeric, globular protein -- Annotation transfered from 1os1 1k3d NO 1 1 NPS NPS 11724534 11724534 Paper says: E. coli PCK is a monomeric, globular protein -- Annotation transfered from 1os1 1k3f NO 6 6 D3 D3 7796917 7796917 Interface geometry conserved with 1q1g (28%) -- Annotation transfered from 1rxy 1k3l NO 2 2 C2 C2 12211029 12211029 glutathione S-transferases are functional dimers. -- Annotation transfered from 1pkw 1k3o NO 2 2 C2 C2 12211029 12211029 glutathione S-transferases are functional dimers. -- Annotation transfered from 1pkw 1k3p NO 6 6 D3 D3 11683626 11683626 Paper says hexamer -- Annotation transfered from 1nxg 1k3t NO 4 4 D2 D2 12044862 12044862 SP says tetramer - papers too 1k3u NO 4 4 C2 C2 11756456 11756456 Paper says a2b2 -- Annotation transfered from 2wsy 1k3w PROBNOT 1 1 NPS NPS 11847126 11847126 Paper says nothing, PISA says monomer and related prots are monomeric (which makes sense). 1k3x PROBNOT 1 1 NPS NPS 11847126 11847126 Paper says nothing, PISA says monomer and related prots are monomeric (which makes sense). -- Annotation transfered from 1k3w 1k3y NO 2 2 C2 C2 12211029 12211029 glutathione S-transferases are functional dimers. -- Annotation transfered from 1pkw 1k40 NO 1 1 NPS NPS 11799401 14527389 Paper says monomer (if not domain swapped) 1k41 NO 2 2 C2 C2 11695900 11695900 -- Annotation transfered from 1e3v 1k44 NO 6 6 D3 D3 12001234 12001234 Interface geometry conserved with 2bef (54%) 1k4e NO 2 2 C2 C2 0 0 Paper says dimer - interface geometry conserved with 1k38 (37%) -- Annotation transfered from 1h8z 1k4f NO 2 2 C2 C2 0 0 Paper says dimer - interface geometry conserved with 1k38 (37%) -- Annotation transfered from 1h8z 1k4j PROBNOT 1 1 NPS NPS 11931774 11931774 Paper says nothing - PISA says monomer 1k4k_1 PROBNOT 1 1 NPS NPS 11796112 11796112 BU changed since last release and is now corrected - However, gel filtration of the ecNMNAT-NaAD complex showed a clean peak at 25 kDa position, indicating that the complex exists as a monomer in solution. - automaticaly inferred from 1k4m 1k4k_2 PROBNOT 1 1 NPS NPS 11796112 11796112 BU changed since last release and is now corrected - However, gel filtration of the ecNMNAT-NaAD complex showed a clean peak at 25 kDa position, indicating that the complex exists as a monomer in solution. - automaticaly inferred from 1k4m 1k4k_3 PROBNOT 1 1 NPS NPS 11796112 11796112 BU changed since last release and is now corrected - However, gel filtration of the ecNMNAT-NaAD complex showed a clean peak at 25 kDa position, indicating that the complex exists as a monomer in solution. - automaticaly inferred from 1k4m 1k4k_4 PROBNOT 1 1 NPS NPS 11796112 11796112 BU changed since last release and is now corrected - However, gel filtration of the ecNMNAT-NaAD complex showed a clean peak at 25 kDa position, indicating that the complex exists as a monomer in solution. - automaticaly inferred from 1k4m 1k4m YES 3 1 C3 NPS 11796112 11796112 However, gel filtration of the ecNMNAT-NaAD complex showed a clean peak at 25 kDa position, indicating that the complex exists as a monomer in solution. 1k4q NO 2 2 C2 C2 11705998 11705998 Paper says dimer -- Annotation transfered from 5grt 1k4w NO 1 1 NPS NPS 11689423 11689423 Paper says: RORbeta can bind as a monomer to the sequence ANNTAGGTCA -- Annotation transfered from 1n4h 1k4y PROBNOT 1 1 NPS NPS 11967565 11967565 Paper says nothing, PISA says monomer 1k51 NO 2 2 C2 C2 11709166 11709166 Domain Swapped dimer 1k54_1 NO 2 2 C2 C2 11724923 11453693 Paper says dimer - interface geometry conserved with 1k38 (37%) - automatic transfer from 1h8z 1k54_2 NO 2 2 C2 C2 11724923 11453693 Paper says dimer - interface geometry conserved with 1k38 (37%) - automatic transfer from 1h8z 1k56_2 NO 2 2 C2 C2 11724923 11453693 Paper says dimer - interface geometry conserved with 1k38 (37%) - automatic transfer from 1h8z 1k57_1 NO 2 2 C2 C2 11724923 11453693 Paper says dimer - interface geometry conserved with 1k38 (37%) - automatic transfer from 1h8z 1k57_2 NO 2 2 C2 C2 11724923 11453693 Paper says dimer - interface geometry conserved with 1k38 (37%) - automatic transfer from 1h8z 1k58 NO 1 1 NPS NPS 11851402 11851402 Human angiogenin is monomeric -- Annotation transfered from 1h52 1k59 NO 1 1 NPS NPS 11851402 11851402 Human angiogenin is monomeric -- Annotation transfered from 1h52 1k5a NO 1 1 NPS NPS 11851402 11851402 Human angiogenin is monomeric -- Annotation transfered from 1h52 1k5b NO 1 1 NPS NPS 11851402 11851402 Human angiogenin is monomeric -- Annotation transfered from 1h52 1k5p NO 1 1 NPS NPS 12939138 12939138 SP says monomer -- Annotation transfered from 1g42 1k5u_1 PROBNOT 1 1 NPS NPS 11847269 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1k5u_2 PROBNOT 1 1 NPS NPS 11847269 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1k5u_3 PROBNOT 1 1 NPS NPS 11847269 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1k5v_1 PROBNOT 1 1 NPS NPS 11847269 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1k5v_2 PROBNOT 1 1 NPS NPS 11847269 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1k62 YES 4 4 NS D2 11747432 11747432 BU changed since last release and is now incorrect - Interface geometry conserved with 1vdk (23%) 1k63 NO 1 1 NPS NPS 12939138 12939138 SP says monomer -- Annotation transfered from 1g42 1k66 NO 2 2 C2 C2 15240481 15240481 Paper says dimer - plus well conserved with 1k68 which is < 40% id) 1k68 YES 2 2 NS C2 15240481 15240481 Wrong reconstruction 1k6c NO 2 2 C2 C2 11790852 11790852 -- Annotation transfered from 1ajx 1k6e NO 1 1 NPS NPS 12939138 12939138 SP says monomer -- Annotation transfered from 1g42 1k6p NO 2 2 C2 C2 11790852 11790852 -- Annotation transfered from 1ajx 1k6r NO 2 2 C2 C2 0 0 Paper says dimer - interface geometry conserved with 1k38 (37%) -- Annotation transfered from 1h8z 1k6s NO 2 2 C2 C2 0 0 Paper says dimer - interface geometry conserved with 1k38 (37%) -- Annotation transfered from 1h8z 1k6t NO 2 2 C2 C2 11790852 11790852 -- Annotation transfered from 1ajx 1k6u NO 1 1 NPS NPS 11734212 11734212 10731422 says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium - pH induced oligomerization 1k6v NO 2 2 C2 C2 11790852 11790852 -- Annotation transfered from 1ajx 1k6w PROBNOT 6 6 D3 D3 11812140 11812140 Paper says: The bacterial enzyme is a hexamer of approximately 426 amino acid residues per subunit, giving a mass of approximately 300 kDa for the active enzyme complex. The yeast enzyme is a homodimer consisting of 17 kDa per subunit. -- Annotation transfered from 1k70 1k70 PROBNOT 6 6 D3 D3 11812140 11812140 Paper says: The bacterial enzyme is a hexamer of approximately 426 amino acid residues per subunit, giving a mass of approximately 300 kDa for the active enzyme complex. The yeast enzyme is a homodimer consisting of 17 kDa per subunit. 1k77 PROBNOT 1 1 NPS NPS 12112708 12112708 1k79_1 PROBYES 1 2 NPS C2 11779502 15591056 BU changed since last release and is now incorrect - Furthermore, the similarities between the Domain swapped dimer - normally monomeric, swapped segment can exist in two conformation, turns out that this conformation is compatible with domain swapping. Paper says: intramolecular interactions in Ets-1{Delta}N301 and the intermolecular interactions in crystalline Ets-1{Delta}N300 validate the proposal that the latter represents a three-dimensional domain-swapped dimer with the in trans position of HI-1 recapitulating its in cis position in a monomeric state. - automaticaly inferred from 1gvj 1k79_2 PROBYES 1 2 NPS C2 11779502 15591056 BU changed since last release and is now incorrect - Furthermore, the similarities between the Domain swapped dimer - normally monomeric, swapped segment can exist in two conformation, turns out that this conformation is compatible with domain swapping. Paper says: intramolecular interactions in Ets-1{Delta}N301 and the intermolecular interactions in crystalline Ets-1{Delta}N300 validate the proposal that the latter represents a three-dimensional domain-swapped dimer with the in trans position of HI-1 recapitulating its in cis position in a monomeric state. - automaticaly inferred from 1gvj 1k7a_1 PROBYES 1 2 NPS C2 11779502 15591056 BU changed since last release and is now incorrect - Furthermore, the similarities between the Domain swapped dimer - normally monomeric, swapped segment can exist in two conformation, turns out that this conformation is compatible with domain swapping. Paper says: intramolecular interactions in Ets-1{Delta}N301 and the intermolecular interactions in crystalline Ets-1{Delta}N300 validate the proposal that the latter represents a three-dimensional domain-swapped dimer with the in trans position of HI-1 recapitulating its in cis position in a monomeric state. - automaticaly inferred from 1gvj 1k7a_2 PROBYES 1 2 NPS C2 11779502 15591056 BU changed since last release and is now incorrect - Furthermore, the similarities between the Domain swapped dimer - normally monomeric, swapped segment can exist in two conformation, turns out that this conformation is compatible with domain swapping. Paper says: intramolecular interactions in Ets-1{Delta}N301 and the intermolecular interactions in crystalline Ets-1{Delta}N300 validate the proposal that the latter represents a three-dimensional domain-swapped dimer with the in trans position of HI-1 recapitulating its in cis position in a monomeric state. - automaticaly inferred from 1gvj 1k7e NO 4 4 C2 C2 11756456 11756456 Paper says a2b2 -- Annotation transfered from 2wsy 1k7f NO 4 4 C2 C2 11756456 11756456 Paper says a2b2 -- Annotation transfered from 2wsy 1k7k PROBYES 1 2 NPS C2 0 0 No paper - PISA says dimer - interface different from 2mjp 1k7l_1 PROBNOT 1 1 NPS NPS 11698662 11587644 SP says: Heterodimer with the retinoid X receptor. - automatic transfer from 1i7g 1k7l_2 PROBNOT 1 1 NPS NPS 11698662 11587644 SP says: Heterodimer with the retinoid X receptor. - automatic transfer from 1i7g 1k7l_3 PROBNOT 1 1 NPS NPS 11698662 11587644 SP says: Heterodimer with the retinoid X receptor. - automatic transfer from 1i7g 1k7l_4 PROBNOT 1 1 NPS NPS 11698662 11587644 SP says: Heterodimer with the retinoid X receptor. - automatic transfer from 1i7g 1k7w NO 4 4 D2 D2 11698398 11698398 Interface geometry conserved with 1fur (23%) -- Annotation transfered from 1tjw 1k7x NO 4 4 C2 C2 11756454 11756454 Paper says a2b2 -- Annotation transfered from 2wsy 1k83 NO 10 10 NPS NPS 11805306 11313498 Correct complex. -- Annotation transfered from 1i3q 1k8c_1 NO 2 2 C2 C2 12102621 12102621 Forms a dimer, paper interesting regarding the evolution of oligomeric state - good candidate - automatic transfer from 1jez 1k8c_2 NO 2 2 C2 C2 12102621 12102621 Forms a dimer, paper interesting regarding the evolution of oligomeric state - good candidate - automatic transfer from 1jez 1k8r PROBNOT 2 2 NPS NPS 11709168 16483931 Paper points to this structure as being biological -- Annotation transfered from 2c5l_1 1k8u NO 2 2 C2 C2 11937060 11937060 Paper says dimer -- Annotation transfered from 1k96 1k8x NO 4 4 C2 C2 12460570 12460570 Paper says a2b2 -- Annotation transfered from 2wsy 1k8y NO 4 4 C2 C2 11756454 11756454 Paper says a2b2 -- Annotation transfered from 2wsy 1k8z NO 4 4 C2 C2 11756454 11756454 Paper says a2b2 -- Annotation transfered from 2wsy 1k94 NO 2 2 C2 C2 11717497 11717497 1k95 YES 1 2 NPS C2 11717497 11717497 1k96 NO 2 2 C2 C2 11937060 11937060 Paper says dimer 1k9b PROBYES 1 3 NPS C3 8954162 8954162 PISA says trimer, similar trimeric geometry in 1pi2 (67%) 1k9d NO 2 2 C2 C2 14573597 15466046 Homodimer -- Annotation transfered from 1mqq 1k9e NO 2 2 C2 C2 14573597 14573597 Homodimer -- Annotation transfered from 1mqq 1k9f NO 2 2 C2 C2 14573597 14573597 Homodimer -- Annotation transfered from 1mqq 1k9i NA 10 1 NS NPS 11739956 11739956 Seems that it is not really a monomer, but it is not really a dimer either - Paper says: The DC-SIGN crystals contain pairs of CRDs cross-linked by the oligosaccharide, in which one monomer forms the same contacts with the oligosaccharide observed for DC-SIGNR, while the partner monomer interacts with the terminal N-acetylglucosamine (GlcNAc) on the alpha 1-3 branch 1k9j NA 2 2 C2 C2 11739956 11739956 I dont get if it is a dimer or not? - In the DC-SIGN crystals, GlcNAc1 also forms a typical C-type lectin Ca2+ coordination and hydrogen bond network at the principal Ca2+ site on the partner monomer in the dimer, thereby cross-linking the two monomers 1k9k NO 2 2 C2 C2 11937060 11937060 Paper says dimer -- Annotation transfered from 1k96 1k9p NO 2 2 C2 C2 11937060 11937060 Paper says dimer -- Annotation transfered from 1k96 1k9s NO 6 6 D3 D3 11786017 11786017 Paper and SP say hexamer -- Annotation transfered from 1ovg 1k9t PROBNOT 1 1 NPS NPS 0 0 -- Annotation transfered from 1ehn 1k9u NO 2 2 C2 C2 12356717 12356717 Paper says dimer - new interface (domain swapped) -- I think this is one of the first naturaly occuring domain swapped dimer I see (closest monomer = 40% id) - interesting 1k9v PROBNOT 1 1 NPS NPS 11839304 11839304 Normally forms a heterodimer (1gpw) 1kaa NO 1 1 NPS NPS 8495201 8495201 Paper says monomeric -- Annotation transfered from 1ena 1kab NO 1 1 NPS NPS 8495201 8495201 Paper says monomeric -- Annotation transfered from 1ena 1kak PROBNOT 1 1 NPS NPS 11741477 11741477 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1kam PROBYES 4 2 D2 C2 11704676 11704676 Paper says: The results of size exclusion chromatography and analytical ultracentrifugation experiments both indicate a molecular weight consistent with a dimer -- very interesting: the biological dimer is reflected by the smaller of the two interfaces (interface geometry conserved with 1kqo (40%)) and the one of size 36 seems wrong!!! very unexpected 1kao PROBNOT 1 1 NPS NPS 9312017 9312017 -- Annotation transfered from 2rap 1kaq YES 6 2 NS C2 11704676 11704676 BU changed since last release and is now incorrect - Paper says: The results of size exclusion chromatography and analytical ultracentrifugation experiments both indicate a molecular weight consistent with a dimer 1kav PROBNOT 1 1 NPS NPS 11741477 11741477 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1kaw YES 4 4 C2 D2 9192620 9192620 Bad reconstruction 1kb2 NO 2 2 NS NS 11980721 11980721 Binds direct DNA repeats -- Annotation transfered from 1kb4 1kb4 NO 2 2 NS NS 11980721 11980721 Binds direct DNA repeats 1kb6 NO 2 2 NS NS 11980721 11980721 Binds direct DNA repeats -- Annotation transfered from 1kb4 1kb9 YES 11 22 NPS C2 11726495 11726495 Interface geometry of the dimerization conserved with 1l0l (37%) 1kba PROBYES 12 2 C6 C2 7947721 7947721 The primary reference indicates that only the dimer is observed (sed. equilibrium analysis). 1kbc_1 PROBNOT 1 1 NPS NPS 9249047 9655333 No clear evidence after a quick search but PISA agrees ... - automatic transfer from 1a85 1kbc_2 PROBNOT 1 1 NPS NPS 9249047 9655333 No clear evidence after a quick search but PISA agrees ... - automatic transfer from 1a85 1kbi NO 4 4 C2 C4 11914072 2329585 The structure is a cyclic tetramer but only C2 is detected because two small domain (out of the four) are unfolded and not visible. -- Annotation transfered from 1fcb 1kbj NO 4 4 C4 C4 11914072 11914072 Paper says tetramer. Note that one domain has been artificially truncated. 1kbl YES 2 2 C2 C2 11790099 11790099 Dimer but wrong interface, the right form is found in 1dik -- problem is PISA does not give the right one -- Annotation transfered from 2dik 1kbn NO 2 2 C2 C2 0 0 -- Annotation transfered from 9gss 1kbo_1 NO 2 2 C2 C2 11735396 11587640 BU changed since last release and is now corrected - - automatic transfer from 1h66_2 1kbo_2 NO 2 2 C2 C2 11735396 11587640 BU changed since last release and is now corrected - - automatic transfer from 1h66_2 1kbq_1 NO 2 2 C2 C2 11735396 11587640 BU changed since last release and is now corrected - - automatic transfer from 1h66_2 1kbq_2 NO 2 2 C2 C2 11735396 11587640 BU changed since last release and is now corrected - - automatic transfer from 1h66_2 1kbr PROBNOT 1 1 NPS NPS 12578370 12578370 EcoCyc & SP say monomer. -- Annotation transfered from 1eqm 1kbu NO 4 4 C4 C4 12051940 12051940 BU changed since last release and is now corrected - 1kbz PROBNOT 2 2 C2 C2 12057193 12057193 PAper says: the observed magnesium dependency of RmlD collectively argue strongly that this dimer represents the physiologically active form of RmlD and is not a crystallization artifact. -- Annotation transfered from 1n2s 1kc1 PROBNOT 2 2 C2 C2 12057193 12057193 PAper says: the observed magnesium dependency of RmlD collectively argue strongly that this dimer represents the physiologically active form of RmlD and is not a crystallization artifact. -- Annotation transfered from 1n2s 1kc2 NO 1 1 NPS NPS 11851339 11851339 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1kc3 PROBNOT 2 2 C2 C2 12057193 12057193 PAper says: the observed magnesium dependency of RmlD collectively argue strongly that this dimer represents the physiologically active form of RmlD and is not a crystallization artifact. -- Annotation transfered from 1n2s 1kc7 YES 2 2 C2 C2 11790099 11790099 Dimer but wrong interface, the right form is found in 1dik -- problem is PISA does not give the right one -- Annotation transfered from 2dik 1kcb NO 3 3 C3 C3 12615072 12615072 -- Annotation transfered from 2nrd 1kce NO 2 2 C2 C2 8973201 8973201 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1kck NO 1 1 NPS NPS 11696539 11696539 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1kcl NO 1 1 NPS NPS 11696539 11696539 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1kcm NO 2 2 C2 C2 11980708 11980708 Paper says dimer 1kct PROBNOT 1 1 NPS NPS 8543039 8543039 Paper says nothing, forms a heterodimer with an apparent 1:1 ratio (1oph) and PISA says monomer -- Annotation transfered from 1oo8 1kcx YES 2 4 C2 D2 14685275 14685275 Paper says: The observation of a CRMP1 homotetramer, burying a total of 9382 Å2 of solvent-accessible surface area, is consistent with prior yeast two-hybrid data and gel-filtration studies, which show that CRMP family members oligomerize and exist as tetramers when purified from brain 1kd7_1 YES 3 60 C3 Icos 11827482 11853672 BU changed since last release and is now incorrect - The virus-like assembly was also detected in solution using gel filtration and electron microscopy. -- very nice example of C3 --> Icosah - automaticaly inferred from 1jh5 1kd7_2 YES 3 60 C3 Icos 11827482 11853672 BU changed since last release and is now incorrect - The virus-like assembly was also detected in solution using gel filtration and electron microscopy. -- very nice example of C3 --> Icosah - automaticaly inferred from 1jh5 1kda NO 1 1 NPS NPS 7795531 7795531 Paper says monomeric -- Annotation transfered from 1ena 1kdb NO 1 1 NPS NPS 7795531 7795531 Paper says monomeric -- Annotation transfered from 1ena 1kdc NO 1 1 NPS NPS 7795531 7795531 Paper says monomeric -- Annotation transfered from 1ena 1kdg NA 2 2 C2 C2 11786022 11786022 Paper says that the enzyme is functional as a monomer, however they say it elutes in two peaks and the interface geometry seem conserved with 1cf3 (20% !). So dimer maybe relevant. 1kdi PROBNOT 1 1 NPS NPS 10206999 10206999 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) 1kdj PROBNOT 1 1 NPS NPS 10206999 10206999 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) -- Annotation transfered from 1kdi 1kdn NO 6 6 D3 D3 9108019 9108019 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1kds_1 PROBNOT 1 1 NPS NPS 12109906 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1kds_2 PROBNOT 1 1 NPS NPS 12109906 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1kdw_1 PROBNOT 1 1 NPS NPS 12109906 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1kdw_2 PROBNOT 1 1 NPS NPS 12109906 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1ke0_1 PROBNOT 1 1 NPS NPS 12109906 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1ke0_2 PROBNOT 1 1 NPS NPS 12109906 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1ke3_1 PROBNOT 1 1 NPS NPS 12109906 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1ke3_2 PROBNOT 1 1 NPS NPS 12109906 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1ke4_1 PROBNOT 1 1 NPS NPS 12109906 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1ke4_2 PROBNOT 1 1 NPS NPS 12109906 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1ke5 NO 1 1 NPS NPS 11728181 11728181 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1ke6 NO 1 1 NPS NPS 11728181 11728181 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1ke7 NO 1 1 NPS NPS 11728181 11728181 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1ke8 NO 1 1 NPS NPS 11728181 11728181 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1ke9 NO 1 1 NPS NPS 11728181 11728181 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1kee PROBNOT 8 8 D2 D2 11729189 11551199 Carbamoyl phosphate synthetase (CPS) from Escherichia coli is allosterically regulated by the metabolites ornithine, IMP, and UMP. Ornithine and IMP function as activators, whereas UMP is an inhibitor. CPS undergoes changes in the state of oligomerization that are dependent on the protein concentration and the binding of allosteric effectors. Ornithine and IMP promote the formation of an (ab)4 tetramer while UMP favors the formation of an (ab)2 dimer. Propagate to all (CPS) please! -) -- Annotation transfered from 1bxr 1keh PROBYES 1 2 NPS C2 11706000 11706000 Same dimer as 1oqz -- PISA finds it 1kei PROBNOT 1 1 NPS NPS 0 0 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1kep NO 2 2 C2 C2 11796113 11796113 Paper says dimer -- Annotation transfered from 1ket 1keq YES 2 1 NS NPS 11851394 11851394 BU changed since last release and is now incorrect - 10529183 says monomer 1ker NO 2 2 C2 C2 11796113 11796113 Paper says dimer -- Annotation transfered from 1ket 1ket NO 2 2 C2 C2 11796113 11796113 Paper says dimer 1keu NO 2 2 C2 C2 11796113 11796113 Paper says dimer 1kev NO 4 4 D2 D2 15299659 0 -- Annotation transfered from 1jqb 1kew NO 2 2 C2 C2 11796113 11796113 Paper says dimer -- Annotation transfered from 1keu 1kf2 NO 1 1 NPS NPS 11856829 11856829 -- Annotation transfered from 6rsa 1kf3 NO 1 1 NPS NPS 11856829 11856829 -- Annotation transfered from 6rsa 1kf4 NO 1 1 NPS NPS 11856829 11856829 -- Annotation transfered from 6rsa 1kf5 NO 1 1 NPS NPS 11856829 11856829 -- Annotation transfered from 6rsa 1kf7 NO 1 1 NPS NPS 11856829 11856829 -- Annotation transfered from 6rsa 1kf8 NO 1 1 NPS NPS 11856829 11856829 -- Annotation transfered from 6rsa 1kfb NO 4 4 C2 C2 12460570 12460570 Paper says a2b2 -- Annotation transfered from 2wsy 1kfc NO 4 4 C2 C2 12460570 12460570 Paper says a2b2 -- Annotation transfered from 2wsy 1kfe NO 4 4 C2 C2 12460570 12460570 Paper says a2b2 -- Annotation transfered from 2wsy 1kff NO 4 4 D2 D2 11910031 11910031 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1kfj NO 4 4 C2 C2 12460570 12460570 Paper says a2b2 -- Annotation transfered from 2wsy 1kfk NO 4 4 C2 C2 12460570 12460570 Paper says a2b2 -- Annotation transfered from 2wsy 1kfl_1 NO 4 4 D2 D2 12126632 10425687 Interface geometry similar to 1oab (57%) - automatic transfer from 1qr7 1kfl_2 NO 4 4 D2 D2 12126632 10425687 Interface geometry similar to 1oab (57%) - automatic transfer from 1qr7 1kfr NO 1 1 NPS NPS 11914507 11914507 11399085 says: Monomeric hemoglobin from the trematode Paramphistomum epiclitum displays very high oxygen affinity 1kfv_1 PROBNOT 1 1 NPS NPS 12065399 15249553 SP says monomer and a review says that these prots are monomeric - automatic transfer from 1tdz 1kfv_2 PROBNOT 1 1 NPS NPS 12065399 15249553 SP says monomer and a review says that these prots are monomeric - automatic transfer from 1tdz 1kg2 PROBNOT 1 1 NPS NPS 0 0 Ecocyc says monomer -- Annotation transfered from 1kg3 1kg3 PROBNOT 1 1 NPS NPS 0 0 Ecocyc says monomer 1kg4 PROBNOT 1 1 NPS NPS 0 0 Ecocyc says monomer -- Annotation transfered from 1kg3 1kg5 PROBNOT 1 1 NPS NPS 0 0 Ecocyc says monomer -- Annotation transfered from 1kg3 1kg6 PROBNOT 1 1 NPS NPS 0 0 Ecocyc says monomer -- Annotation transfered from 1kg3 1kg7 PROBNOT 1 1 NPS NPS 0 0 Ecocyc says monomer -- Annotation transfered from 1kg3 1kg8 NO 3 3 C3 C3 11721006 11721006 SP says trimer -- Annotation transfered from 2brd 1kg9 NO 3 3 C3 C3 11721006 11721006 SP says trimer -- Annotation transfered from 2brd 1kgb NO 3 3 C3 C3 11721006 11721006 SP says trimer -- Annotation transfered from 2brd 1kgd NA 1 1 NPS NPS 11729206 11729206 Paper says nothing, PISA says dimer 1kge PROBNOT 1 1 NPS NPS 8987980 8987980 -- Annotation transfered from 1ghi 1kgf PROBYES 2 1 C2 NPS 8987980 9521648 Class A betalactamase are apparently monomeric in solution (said in paper) 1kgg PROBNOT 1 1 NPS NPS 10436083 10436083 -- Annotation transfered from 1ghi 1kgi NO 4 4 D2 D2 11995998 11995998 Paper says tetramer -- Annotation transfered from 1gke 1kgj NO 4 4 D2 D2 11995999 11995999 Paper says tetramer -- Annotation transfered from 1gke 1kh8 NO 1 1 NPS NPS 16199662 16199662 -- Annotation transfered from 6rsa 1khp PROBNOT 1 1 NPS NPS 15357669 15357669 Papain is a 23,400-dalton single polypeptide -- Annotation transfered from 9pap 1khq PROBNOT 1 1 NPS NPS 15357669 15357669 Papain is a 23,400-dalton single polypeptide -- Annotation transfered from 9pap 1khr_1 NO 3 3 C3 C3 11841212 11841212 Interface geometry conserved with 1xat (42%) - automatic transfer from 1kk6 1khr_2 NO 3 3 C3 C3 11841212 11841212 Interface geometry conserved with 1xat (42%) - automatic transfer from 1kk6 1khx NO 3 3 C3 C3 11779503 11779503 Paper says trimer 1kia NO 4 4 D2 D2 0 0 Paper says tetramer -- Annotation transfered from 1d2h 1kib NA 24 1 Octa NPS 12077429 12077429 SP says monomer, paper of 1f1f (98% id) says elutes as a dimer. Unclear - possibly a monomer-dimer equilibrium. 1kic NO 2 2 C2 C2 11854281 11854281 Paper says dimer: The T. vivax IAG-NH is a homodimer, with each subunit consisting of ten beta-strands, 12 alpha-helices and three small 3(10)-helices. - We estimated the apparent molecular mass of the active nucleoside hydrolase from T. vivax using gel chromatography on a 10/30 Superdex-200 HR column. The enzyme elutes with a distribution coefficient (Kd in equation (1)) of 0.42 corresponding to a calculated molecular mass of 59,600 Da. Denaturing polyacrylamide gel electrophoresis gave a single band with a subunit molecular mass of approximately 35,000 Da, consistent with the predicted subunit molecular mass of 37,584 Da. -- Annotation transfered from 1hoz 1kie NO 2 2 C2 C2 11854281 11854281 Paper says dimer: The T. vivax IAG-NH is a homodimer, with each subunit consisting of ten beta-strands, 12 alpha-helices and three small 3(10)-helices. - We estimated the apparent molecular mass of the active nucleoside hydrolase from T. vivax using gel chromatography on a 10/30 Superdex-200 HR column. The enzyme elutes with a distribution coefficient (Kd in equation (1)) of 0.42 corresponding to a calculated molecular mass of 59,600 Da. Denaturing polyacrylamide gel electrophoresis gave a single band with a subunit molecular mass of approximately 35,000 Da, consistent with the predicted subunit molecular mass of 37,584 Da. -- Annotation transfered from 1hoz 1kiv PROBNOT 1 1 NPS NPS 10026282 10026282 Real protein 4500 aa! So monomeric seems right - paper says nothing - PISA says monomeric -- Annotation transfered from 3kiv 1kj7 NO 2 2 C2 C2 12005435 12005435 -- Annotation transfered from 1ajx 1kj8 NO 2 2 C2 C2 11953435 11953435 SP and paper say dimer - Interface geometry conserved with 1b6r (24%) -- Annotation transfered from 1eyz 1kj9 NO 2 2 C2 C2 11953435 11953435 SP and paper say dimer - Interface geometry conserved with 1b6r (24%) -- Annotation transfered from 1eyz 1kjf NO 2 2 C2 C2 12005435 12005435 -- Annotation transfered from 1ajx 1kjg NO 2 2 C2 C2 12005435 12005435 -- Annotation transfered from 1ajx 1kjh NO 2 2 C2 C2 12005435 12005435 -- Annotation transfered from 1ajx 1kji NO 2 2 C2 C2 11953435 11953435 SP and paper say dimer - Interface geometry conserved with 1b6r (24%) -- Annotation transfered from 1eyz 1kjj NO 2 2 C2 C2 11953435 11953435 SP and paper say dimer - Interface geometry conserved with 1b6r (24%) -- Annotation transfered from 1eyz 1kjl NO 1 1 NPS NPS 15701008 9582341 Paper says monomer - automatic transfer from 1a3k 1kjo PROBNOT 1 1 NPS NPS 0 0 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1kjp PROBNOT 1 1 NPS NPS 0 0 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1kjq NO 2 2 C2 C2 11953435 11953435 SP and paper say dimer - Interface geometry conserved with 1b6r (24%) -- Annotation transfered from 1eyz 1kjr NO 1 1 NPS NPS 15701008 9582341 Paper says monomer - automatic transfer from 1a3k 1kjt PROBNOT 1 1 NPS NPS 11818336 11818336 Paper mentions gel filtration and no oligomer - PISA says monomer -- Annotation transfered from 1gnu 1kjz NO 1 1 NPS NPS 11927566 11927566 Paper says: Heterotrimer composed of an alpha, a beta and a gamma chain and that s it. They show that gamma is at the core. -- Annotation transfered from 1kk1 1kk0 NO 1 1 NPS NPS 11927566 11927566 Paper says: Heterotrimer composed of an alpha, a beta and a gamma chain and that s it. They show that gamma is at the core. -- Annotation transfered from 1kk1 1kk1 NO 1 1 NPS NPS 11927566 11927566 Paper says: Heterotrimer composed of an alpha, a beta and a gamma chain and that s it. They show that gamma is at the core. 1kk2 NO 1 1 NPS NPS 11927566 11927566 Paper says: Heterotrimer composed of an alpha, a beta and a gamma chain and that s it. They show that gamma is at the core. -- Annotation transfered from 1kk1 1kk3 NO 1 1 NPS NPS 11927566 11927566 Paper says: Heterotrimer composed of an alpha, a beta and a gamma chain and that s it. They show that gamma is at the core. -- Annotation transfered from 1kk1 1kk4_1 NO 3 3 C3 C3 11841212 11841212 Interface geometry conserved with 1xat (42%) - automatic transfer from 1kk6 1kk4_2 NO 3 3 C3 C3 11841212 11841212 Interface geometry conserved with 1xat (42%) - automatic transfer from 1kk6 1kk5_1 NO 3 3 C3 C3 11841212 11841212 Interface geometry conserved with 1xat (42%) - automatic transfer from 1kk6 1kk5_2 NO 3 3 C3 C3 11841212 11841212 Interface geometry conserved with 1xat (42%) - automatic transfer from 1kk6 1kk6 NO 3 3 C3 C3 11841212 11841212 Interface geometry conserved with 1xat (42%) 1kkc NO 4 4 D2 D2 11801664 11801664 Paper says tetramer - looks like the human one 1kkh NA 1 1 NPS NPS 11751891 11751891 Paper says: The structure of MVK contains all 312 residues of the wild-type MVK as well as five residues from the N-terminal histidine tag fusion. It is a monomer in crystal, although the dimer was reported in the aqueous solution. 1kkj NO 2 2 C2 C2 11877399 11877399 Paper says the quaternary structure of bsSHMT is a dimer (gel filtration) -- Annotation transfered from 1kkp 1kkk PROBNOT 1 1 NPS NPS 0 0 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1kkp NO 2 2 C2 C2 11877399 11877399 Paper says the quaternary structure of bsSHMT is a dimer (gel filtration) 1kkq_1 PROBYES 4 1 NS NPS 11845213 11587644 BU changed since last release and is now incorrect - SP says: Heterodimer with the retinoid X receptor. - automaticaly inferred from 1i7g 1kku YES 6 6 D3 D3 11751893 11751893 Paper says: The results from the analytical ultracentrifugation studies are consistent with the formation of a hexamer in solution under certain conditions - our data cannot rule out a possible hexamer dimer tetramer equilibrium -- wrong interface used 1kl1 NO 2 2 C2 C2 11877399 11877399 Paper says the quaternary structure of bsSHMT is a dimer (gel filtration) -- Annotation transfered from 1kkp 1kl2 NO 2 2 C2 C2 11877399 11877399 Paper says the quaternary structure of bsSHMT is a dimer (gel filtration) -- Annotation transfered from 1kkp 1kl3 NO 4 4 D2 D2 11910031 11910031 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1kl4 NO 4 4 D2 D2 11910031 11910031 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1kl5 NO 4 4 D2 D2 11910031 11910031 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1kl6 PROBNOT 1 1 NPS NPS 0 0 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1klk PROBNOT 1 1 NPS NPS 12037296 12037296 PISA also says monomer - Human is monomeric so I guess it should be - Only Thermogota seems to be dimeric -- Annotation transfered from 1cd2 1kll YES 2 2 C2 C2 12121648 12121648 Paper says: In all three crystal structures, a single monomer occupies the asymmetric unit of the C2 unit cell, and two monomers form a close association with the resultant 2-fold axis of the MRD dimer corresponding to the crystallographic dyad. This is consistent with our gel filtration results (data not shown), which indicate that a dimer is the predominant species in solution. - domain swapped dimer -- wrong interface 1klt PROBNOT 1 1 NPS NPS 9400368 9400368 Paper says nothing, PISA says monomer -- Annotation transfered from 1nn6 1kly YES 2 2 C2 C2 11900543 11900543 SP says dimer -- Wrong interface 1klz YES 2 2 C2 C2 11900543 11900543 SP says dimer -- Wrong interface -- Annotation transfered from 1kly 1km0_1 NO 2 2 C2 C2 11900543 12011084 SP says dimer - interface geometry conserved with 1q6q (26%) - automatic transfer from 1lor 1km0_2 NO 2 2 C2 C2 11900543 12011084 SP says dimer - interface geometry conserved with 1q6q (26%) - automatic transfer from 1lor 1km1 NO 2 2 C2 C2 11900543 11900543 SP says dimer - interface geometry conserved with 1q6q (26%) 1km2 YES 2 2 C2 C2 11900543 11900543 SP says dimer -- Wrong interface -- Annotation transfered from 1kly 1km3 YES 2 2 C2 C2 11900543 11900543 SP says dimer -- Wrong interface -- Annotation transfered from 1kly 1km4 YES 2 2 C2 C2 11900543 11900543 SP says dimer -- Wrong interface -- Annotation transfered from 1kly 1km5 YES 2 2 C2 C2 11900543 11900543 SP says dimer -- Wrong interface -- Annotation transfered from 1kly 1km6 YES 2 2 C2 C2 11900543 11900543 SP says dimer -- Wrong interface -- Annotation transfered from 1kly 1km8 NO 1 1 NPS NPS 0 0 1km9 NO 1 1 NPS NPS 0 0 -- Annotation transfered from 1km8 1kme_1 YES 1 3 NPS C3 11829498 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1kme_2 YES 1 3 NPS C3 11829498 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1kmj NO 2 2 C2 C2 11853669 11853669 -- Annotation transfered from 1i29 1kmk NO 2 2 C2 C2 11853669 11853669 -- Annotation transfered from 1i29 1kmq PROBNOT 1 1 NPS NPS 12777804 12777804 -- Annotation transfered from 1a2b 1kms PROBNOT 1 1 NPS NPS 12096917 12096917 -- Annotation transfered from 1s3u 1kmv PROBNOT 1 1 NPS NPS 12096917 12096917 -- Annotation transfered from 1s3u 1kmy NO 8 8 D4 D4 9857017 9857017 Interface geometry conserved with 1kw6 (66%) -- Annotation transfered from 1knf 1kmz YES 2 2 NS C2 12121648 12121648 Paper says: In all three crystal structures, a single monomer occupies the asymmetric unit of the C2 unit cell, and two monomers form a close association with the resultant 2-fold axis of the MRD dimer corresponding to the crystallographic dyad. This is consistent with our gel filtration results (data not shown), which indicate that a dimer is the predominant species in solution. - domain swapped dimer 1kn0 PROBNOT 11 11 C11 C11 12191481 12191481 Paper says undecamer 1kn3 PROBNOT 1 1 NPS NPS 12037323 12037323 Nothing said in the paper - PISA says monomer. An email was sent to the authors 1knc NO 3 3 C3 C3 11799204 11799204 Paper says trimer - interface conserved with 1p8c (37%) -- PISA very wrong - error 1knd NO 8 8 D4 D4 9857017 9857017 Interface geometry conserved with 1kw6 (66%) -- Annotation transfered from 1knf 1knf NO 8 8 D4 D4 9857017 9857017 Interface geometry conserved with 1kw6 (66%) 1kng PROBNOT 1 1 NPS NPS 12121652 12121652 Paper says nothing, PISA says monomer 1kni NO 1 1 NPS NPS 1304882 1304882 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1knp PROBNOT 1 1 NPS NPS 11863440 11863440 SP says monomer 1knq PROBNOT 2 2 C2 C2 12054802 12054802 Paper says: In solution, GntK is active as a dimer composed of two identical subunits. -- Annotation transfered from 1ko5 1knr PROBNOT 1 1 NPS NPS 11863440 11863440 SP says monomer -- Annotation transfered from 1knp 1knt PROBNOT 1 1 NPS NPS 7533217 7533217 SP says: Trimers composed of three different chains: alpha 1(VI), alpha 2(VI), and alpha 3(VI) -- Annotation transfered from 2knt 1knu NO 2 2 C2 C2 11831892 11831892 Paper says homodimer -- Annotation transfered from 1prg 1ko1 PROBNOT 2 2 C2 C2 12054802 12054802 Paper says: In solution, GntK is active as a dimer composed of two identical subunits. -- Annotation transfered from 1ko5 1ko2 PROBNOT 1 1 NPS NPS 0 0 No paper, PISA says monomer 1ko3 PROBNOT 1 1 NPS NPS 0 0 No paper, PISA says monomer -- Annotation transfered from 1ko2 1ko4 PROBNOT 2 2 C2 C2 12054802 12054802 Paper says: In solution, GntK is active as a dimer composed of two identical subunits. -- Annotation transfered from 1ko5 1ko5 PROBNOT 2 2 C2 C2 12054802 12054802 Paper says: In solution, GntK is active as a dimer composed of two identical subunits. 1ko7_1 YES 3 6 C3 D3 11904409 11904409 BU changed since last release and is now incorrect - Paper says hexamer 1ko7_2 YES 3 3 C3 D3 11904409 11904409 BU changed since last release and is now incorrect - Paper says hexamer 1ko8 PROBNOT 2 2 C2 C2 12054802 12054802 Paper says: In solution, GntK is active as a dimer composed of two identical subunits. -- Annotation transfered from 1ko5 1kob YES 2 1 C2 NPS 9003756 9003756 Dynamic light scattering (DynaPro-801, Protein Solutions) indicated a hydrodynamic radius of 3.2 nm, consistent with a monomeric species. 1kof PROBNOT 2 2 C2 C2 12054802 12054802 Paper says: In solution, GntK is active as a dimer composed of two identical subunits. -- Annotation transfered from 1ko5 1koj NO 2 2 C2 C2 11983887 11983887 -- Annotation transfered from 1iat 1kok PROBNOT 1 1 NPS NPS 12237229 12237229 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1kol NO 4 4 D2 D2 12445786 12445786 1kop PROBYES 2 1 NS NPS 9761692 9761692 Paper does not mention a dimer, PISA says monomer 1koq PROBYES 2 1 NS NPS 9761692 9761692 Paper does not mention a dimer, PISA says monomer -- Annotation transfered from 1kop 1kou PROBNOT 1 1 NPS NPS 11914481 11914481 SP says monomer -- Annotation transfered from 1s1z 1kp0 NO 2 2 C2 C2 12136144 12136144 Paper says dimer 1kp6 NA 1 3 NPS C3 10400668 10400668 Paper suggests that it is a trimer but no evidence it providen, and PISA says monomer 1kp8 NO 14 14 D7 D7 12654267 12654267 1kpm_1 PROBNOT 1 1 NPS NPS 12079380 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 1kpm_2 PROBNOT 1 1 NPS NPS 12079380 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 1kpo NO 14 14 D7 D7 0 0 -- Annotation transfered from 1kp8 1kq0 PROBNOT 1 1 NPS NPS 16540317 16540317 Paper says nothing, PISA says monomer -- Annotation transfered from 1b6a 1kq3 YES 1 8 NPS D4 12193646 12193646 Interface geometry conserved with 1jq5 (48%) 1kq6 PROBNOT 1 1 NPS NPS 0 0 cf. 1o7k 1kq7 NO 4 4 D2 D2 12021453 12021453 Interface geometry conserved with 1q5n (22%) -- Annotation transfered from 1fur 1kq9 PROBNOT 1 1 NPS NPS 16540317 16540317 Paper says nothing, PISA says monomer -- Annotation transfered from 1b6a 1kqa NO 3 3 C3 C3 11937062 11937062 Paper says: The LβH domain participates in the subunit interface of these trimeric enzymes and in all known cases forms part of their active sites - interface geometry conserved with 1xat (37%) -- Annotation transfered from 1krr 1kqj PROBNOT 1 1 NPS NPS 11900536 11900536 Ecocyc says monomer -- Annotation transfered from 1kg3 1kqn NO 6 6 D3 D3 11788603 11788603 Paper says: The results from the analytical ultracentrifugation studies are consistent with the formation of a hexamer in solution under certain conditions - our data cannot rule out a possible hexamer dimer tetramer equilibrium -- 1kqo NO 6 6 D3 D3 11788603 11788603 Paper says: The results from the analytical ultracentrifugation studies are consistent with the formation of a hexamer in solution under certain conditions - our data cannot rule out a possible hexamer dimer tetramer equilibrium -- -- Annotation transfered from 1kqn 1kqu NO 1 1 NPS NPS 12616631 8979149 Human PLA predominantly exists as a monomer 1kqw PROBNOT 1 1 NPS NPS 12162964 12162964 Paper says gel filtration carried out - still no oligomer mentioned and PISA says monomer 1kqx PROBNOT 1 1 NPS NPS 12162964 12162964 Paper says gel filtration carried out - still no oligomer mentioned and PISA says monomer -- Annotation transfered from 1kqw 1kqy PROBNOT 1 1 NPS NPS 11846790 11846790 -- Annotation transfered from 1kr1 1kqz PROBNOT 1 1 NPS NPS 11846790 11846790 -- Annotation transfered from 1kr1 1kr0 PROBNOT 1 1 NPS NPS 11846790 11846790 -- Annotation transfered from 1kr1 1kr1 PROBNOT 1 1 NPS NPS 11846790 11846790 1kr2 NO 6 6 D3 D3 11788603 11788603 Paper says: The results from the analytical ultracentrifugation studies are consistent with the formation of a hexamer in solution under certain conditions - our data cannot rule out a possible hexamer dimer tetramer equilibrium -- -- Annotation transfered from 1kqn 1kr3_1 PROBNOT 1 1 NPS NPS 12019104 9730812 BU changed since last release and is now corrected - - automaticaly inferred from 1a7t 1kr3_2 PROBNOT 1 1 NPS NPS 12019104 9730812 BU changed since last release and is now corrected - - automaticaly inferred from 1a7t 1kr4 NO 3 3 C3 C3 14705033 14705033 said in paper 1kr5 PROBNOT 1 1 NPS NPS 11792715 11792715 SP says monomer -- Annotation transfered from 1i1n 1kr6 PROBNOT 1 1 NPS NPS 0 0 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1kra NO 9 9 C3 C3 8718850 8718850 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1krb NO 9 9 C3 C3 8718850 8718850 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1krc NO 9 9 C3 C3 8718850 8718850 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 1krj PROBNOT 1 1 NPS NPS 10608846 10608846 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1krn PROBNOT 1 1 NPS NPS 15299951 0 This is just a very small domain of much a larger protein so probably monomeric -- Annotation transfered from 1pk4 1kro PROBNOT 1 1 NPS NPS 0 0 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1krq NO 24 24 Octa Octa 0 0 BU changed since last release and is now corrected - Interface geometry conserved with 1lb3 (28%) 1krr NO 3 3 C3 C3 11937062 11937062 Paper says: The LβH domain participates in the subunit interface of these trimeric enzymes and in all known cases forms part of their active sites - interface geometry conserved with 1xat (37%) 1kru NO 3 3 C3 C3 11937062 11937062 Paper says: The LβH domain participates in the subunit interface of these trimeric enzymes and in all known cases forms part of their active sites - interface geometry conserved with 1xat (37%) -- Annotation transfered from 1krr 1krv NO 3 3 C3 C3 11937062 11937062 Paper says: The LβH domain participates in the subunit interface of these trimeric enzymes and in all known cases forms part of their active sites - interface geometry conserved with 1xat (37%) -- Annotation transfered from 1krr 1ks2 NO 2 2 C2 C2 12517338 12517338 Interface geometry conserved with 1uj6 (40%) -- Annotation transfered from 1lkz 1ks3 NO 1 1 NPS NPS 12646375 12646375 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1ks4 PROBNOT 1 1 NPS NPS 11914491 11914491 Paper says nothing, PISA says monomer -- Annotation transfered from 1ks5 1ks5 PROBNOT 1 1 NPS NPS 11914491 11914491 Paper says nothing, PISA says monomer 1ks7 PROBNOT 1 1 NPS NPS 0 0 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1ksi NO 2 2 C2 C2 8805580 8805580 Interface geometry conserved with 1sii (25%) 1ksk NO 1 1 NPS NPS 11953756 11953756 Gel filtration indicated that RsuA exists as a monomer in solution, as observed in the crystal structure -- Annotation transfered from 1ksl 1ksl NO 1 1 NPS NPS 11953756 11953756 Gel filtration indicated that RsuA exists as a monomer in solution, as observed in the crystal structure 1ksn PROBNOT 2 2 NPS NPS 12039587 12039587 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1kso NO 2 2 C2 C2 12136135 12136135 Paper says dimer 1kss PROBNOT 1 1 NPS NPS 12093271 12093271 SP says monomer -- Annotation transfered from 1qjd 1ksu_1 PROBNOT 1 1 NPS NPS 12093271 10581550 SP says monomer - automatic transfer from 1qjd 1ksu_2 PROBNOT 1 1 NPS NPS 12093271 10581550 SP says monomer - automatic transfer from 1qjd 1ksv NO 1 1 NPS NPS 11953756 11953756 Gel filtration indicated that RsuA exists as a monomer in solution, as observed in the crystal structure -- Annotation transfered from 1ksl 1ksw PROBNOT 1 1 NPS NPS 11841936 11841936 -- Annotation transfered from 2ptk 1ksx_1 PROBYES 4 2 C2 C2 11889054 10949036 BU changed since last release and is now incorrect - PAper says dimer - automaticaly inferred from 1f08 1ksx_2 PROBYES 4 2 C2 C2 11889054 10949036 BU changed since last release and is now incorrect - PAper says dimer - automaticaly inferred from 1f08 1ksy_1 PROBNOT 2 2 C2 C2 11889054 10949036 PAper says dimer - automatic transfer from 1f08 1ksy_2 PROBNOT 2 2 C2 C2 11889054 10949036 PAper says dimer - automatic transfer from 1f08 1kt3 NO 1 1 NPS NPS 12787682 12787682 Circulating in the plasma, the monomeric RBP molecule (21 kDa) is found associated in a macromolecular complex with the tetrameric thyroxine-binding transthyretin (55 kDa). The formation of the RBP–transthyretin complex is believed to prevent filtration through renal glomeruli of the relatively small RBP molecule. -- Annotation transfered from 1kt5 1kt4 NO 1 1 NPS NPS 12787682 12787682 Circulating in the plasma, the monomeric RBP molecule (21 kDa) is found associated in a macromolecular complex with the tetrameric thyroxine-binding transthyretin (55 kDa). The formation of the RBP–transthyretin complex is believed to prevent filtration through renal glomeruli of the relatively small RBP molecule. -- Annotation transfered from 1kt5 1kt5 NO 1 1 NPS NPS 12787682 12787682 Circulating in the plasma, the monomeric RBP molecule (21 kDa) is found associated in a macromolecular complex with the tetrameric thyroxine-binding transthyretin (55 kDa). The formation of the RBP–transthyretin complex is believed to prevent filtration through renal glomeruli of the relatively small RBP molecule. 1kt6 NO 1 1 NPS NPS 12787682 12787682 Circulating in the plasma, the monomeric RBP molecule (21 kDa) is found associated in a macromolecular complex with the tetrameric thyroxine-binding transthyretin (55 kDa). The formation of the RBP–transthyretin complex is believed to prevent filtration through renal glomeruli of the relatively small RBP molecule. -- Annotation transfered from 1kt5 1kt7 NO 1 1 NPS NPS 12787682 12787682 Circulating in the plasma, the monomeric RBP molecule (21 kDa) is found associated in a macromolecular complex with the tetrameric thyroxine-binding transthyretin (55 kDa). The formation of the RBP–transthyretin complex is believed to prevent filtration through renal glomeruli of the relatively small RBP molecule. -- Annotation transfered from 1kt5 1kt8 NO 2 2 C2 C2 12269802 12269802 Paper says dimer: The mammalian BCATs are homodimers with molecular masses ranging from about 41000 to 46000. - SP too -- Annotation transfered from 1kta 1kt9 NO 1 1 NPS NPS 11937063 11937063 Paper says: The C. elegans Ap4A hydrolase belongs to the Nudix family and is the first monomeric member to have its crystal structure determined. 1kta NO 2 2 C2 C2 12269802 12269802 Paper says dimer: The mammalian BCATs are homodimers with molecular masses ranging from about 41000 to 46000. - SP too 1ktb NO 2 2 C2 C2 12005440 12005440 Interface geometry conserved with 1r47 (53%) -- Annotation transfered from 1ktc 1ktc NO 2 2 C2 C2 12005440 12005440 Interface geometry conserved with 1r47 (53%) 1kte PROBNOT 1 1 NPS NPS 8535236 8535236 Paper says: treated with 10 mM hydroxyethyl disulfide at room temperature for 30 min to convertit to the oxidized form - PISA says monomer 1ktg_1 NO 1 1 NPS NPS 11937063 11937063 Paper says: The C. elegans Ap4A hydrolase belongs to the Nudix family and is the first monomeric member to have its crystal structure determined. - automatic transfer from 1kt9 1ktg_2 NO 1 1 NPS NPS 11937063 11937063 Paper says: The C. elegans Ap4A hydrolase belongs to the Nudix family and is the first monomeric member to have its crystal structure determined. - automatic transfer from 1kt9 1kth PROBNOT 1 1 NPS NPS 12077460 12077460 SP says: Trimers composed of three different chains: alpha 1(VI), alpha 2(VI), and alpha 3(VI) -- Annotation transfered from 2knt 1kti PROBYES 2 2 C2 C2 11895439 11895439 Wrong interface of the dimer 1ktn PROBNOT 2 2 C2 C2 0 0 Interface geometry somewhat conserved with 1mzh (32%) -- interesting: first case that I see where the place of the interaction is conserved but interface has completely changed 1kto PROBNOT 1 1 NPS NPS 0 0 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1ku3 NO 1 1 NPS NPS 11931761 11931761 1ku7 PROBYES 2 1 C2 NPS 11931761 11931761 Seth Darst said the functional unit a monomer 1kuf PROBNOT 1 1 NPS NPS 12077431 12077431 Related proteins seem monomeric and PISA says monomer -- Annotation transfered from 1kui 1kug PROBNOT 1 1 NPS NPS 12071970 12071970 Related proteins seem monomeric and PISA says monomer -- Annotation transfered from 1kui 1kui PROBNOT 1 1 NPS NPS 12071970 12071970 Related proteins seem monomeric and PISA says monomer 1kuk PROBNOT 1 1 NPS NPS 12071970 12071970 Related proteins seem monomeric - interesting PISA error: almost no contact!! 1kv0 NA 2 1 C2 NPS 15321715 15321715 Paper says it is a dimer but I do not believe it, an email was sent 1kv1 PROBNOT 1 1 NPS NPS 11896401 11896401 1kv2 PROBNOT 1 1 NPS NPS 11896401 11896401 -- Annotation transfered from 1kv1 1kv5 PROBNOT 2 2 C2 C2 11997014 11997014 SP says dimer -- Annotation transfered from 6tim 1kv6 NO 2 2 C2 C2 11864604 11864604 Paper says dimer 1kv7 PROBNOT 1 1 NPS NPS 11867755 11867755 Paper says nothing, PISA says monomer -- Annotation transfered from 1n68 1kv8 NO 2 2 C2 C2 11900527 11900527 Interface geometry conserved with 1lor -- Annotation transfered from 1q6q 1kva PROBNOT 1 1 NPS NPS 8931125 8931125 SP says monomer -- Annotation transfered from 1f21 1kvb PROBNOT 1 1 NPS NPS 8931125 8931125 SP says monomer -- Annotation transfered from 1f21 1kvc PROBNOT 1 1 NPS NPS 8931125 8931125 SP says monomer -- Annotation transfered from 1f21 1kvl_1 PROBNOT 1 1 NPS NPS 12005439 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1kvl_2 PROBNOT 1 1 NPS NPS 12005439 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1kvm_1 PROBNOT 1 1 NPS NPS 12005439 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1kvm_2 PROBNOT 1 1 NPS NPS 12005439 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1kvo_1 PROBYES 2 1 C2 NPS 8831753 8979149 BU changed since last release and is now incorrect - Human PLA predominantly exists as a monomer - automaticaly inferred from 1poe 1kvo_2 PROBYES 2 1 C2 NPS 8831753 8979149 BU changed since last release and is now incorrect - Human PLA predominantly exists as a monomer - automaticaly inferred from 1poe 1kvo_3 PROBYES 2 1 C2 NPS 8831753 8979149 BU changed since last release and is now incorrect - Human PLA predominantly exists as a monomer - automaticaly inferred from 1poe 1kvq NO 2 2 C2 C2 9271499 9271499 SP says homodimer -- Annotation transfered from 2udp 1kvr NO 2 2 C2 C2 9271499 9271499 SP says homodimer -- Annotation transfered from 2udp 1kvs YES 1 2 NPS C2 9271499 9271499 1kvt NO 2 2 C2 C2 9271499 9271499 SP says homodimer -- Annotation transfered from 2udp 1kvu NO 2 2 C2 C2 9271498 9271498 SP says homodimer -- Annotation transfered from 2udp 1kvw PROBNOT 1 1 NPS NPS 10089353 10089353 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1o2e 1kvx PROBNOT 1 1 NPS NPS 10089353 10089353 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1o2e 1kvy PROBYES 2 1 C2 NPS 10089353 10089353 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1bpq 1kw0 NO 2 2 C2 C2 12126628 12126628 Dimer because no tetramerization domain - SP is wrong (says dimer) -- Annotation transfered from 1j8u 1kw1 NO 2 2 C2 C2 11900527 11900527 Interface geometry conserved with 1lor -- Annotation transfered from 1q6q 1kw3 NO 8 8 D4 D4 12206778 12206778 Interface geometry conserved with 1lgt (66%) -- Annotation transfered from 1eil 1kw5 NO 1 1 NPS NPS 12646375 12646375 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1kw6 NO 8 8 D4 D4 12206778 12206778 Interface geometry conserved with 1lgt (66%) -- Annotation transfered from 1eil 1kw7 NO 1 1 NPS NPS 12646375 12646375 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1kw8 NO 8 8 D4 D4 12206778 12206778 Interface geometry conserved with 1lgt (66%) -- Annotation transfered from 1eil 1kw9 NO 8 8 D4 D4 12206778 12206778 Interface geometry conserved with 1lgt (66%) -- Annotation transfered from 1eil 1kwb NO 8 8 D4 D4 12206778 12206778 Interface geometry conserved with 1lgt (66%) -- Annotation transfered from 1eil 1kwc NO 8 8 D4 D4 12206778 12206778 Interface geometry conserved with 1lgt (66%) -- Annotation transfered from 1eil 1kwi NO 1 1 NPS NPS 12377122 12377122 -- Annotation transfered from 1pfp 1kwn NO 1 1 NPS NPS 12112683 12112683 Thaumatin is a stable monomeric protein of 22kDa -- Annotation transfered from 1thu 1kwp_1 PROBNOT 1 1 NPS NPS 12171911 12791252 Paper says nothing about an oligomer - PISa says 12 subs ... wrong? (I think so) - automatic transfer from 1ny3 1kwp_2 PROBNOT 1 1 NPS NPS 12171911 12791252 Paper says nothing about an oligomer - PISa says 12 subs ... wrong? (I think so) - automatic transfer from 1ny3 1kwq PROBNOT 1 1 NPS NPS 12166932 0 9000633 says monomeric -- Annotation transfered from 1uga 1kwr PROBNOT 1 1 NPS NPS 12166932 0 9000633 says monomeric -- Annotation transfered from 1uga 1kxa NA 1 1 NPS NPS 8831786 8831786 Unclear, email sent -- Annotation transfered from 2snv 1kxb NA 1 1 NPS NPS 8831786 8831786 Unclear, email sent -- Annotation transfered from 2snv 1kxc NA 1 1 NPS NPS 8831786 8831786 Unclear, email sent -- Annotation transfered from 2snv 1kxd NA 1 1 NPS NPS 8831786 8831786 Unclear, email sent -- Annotation transfered from 2snv 1kxe NA 1 1 NPS NPS 8831786 8831786 Unclear, email sent -- Annotation transfered from 2snv 1kxf NA 1 1 NPS NPS 8831786 8831786 Unclear, email sent -- Annotation transfered from 2snv 1kxg_1 YES 3 60 C3 Icos 11862220 11853672 BU changed since last release and is now incorrect - The virus-like assembly was also detected in solution using gel filtration and electron microscopy. -- very nice example of C3 --> Icosah - automaticaly inferred from 1jh5 1kxg_2 YES 3 60 C3 Icos 11862220 11853672 BU changed since last release and is now incorrect - The virus-like assembly was also detected in solution using gel filtration and electron microscopy. -- very nice example of C3 --> Icosah - automaticaly inferred from 1jh5 1kxi NA 2 2 C2 C2 9054545 9054545 Therefore, all the reported CTX crystal structures appear to exhibit multimeric association, whereas structures obtained by NMR suggest the existance of CTX monomers below pH 6.0. 1kxj_1 PROBNOT 1 1 NPS NPS 12360532 11839304 Normally forms a heterodimer (1gpw) - automatic transfer from 1k9v 1kxj_2 PROBNOT 1 1 NPS NPS 12360532 11839304 Normally forms a heterodimer (1gpw) - automatic transfer from 1k9v 1kxm PROBNOT 1 1 NPS NPS 11967381 11967381 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1kxn PROBNOT 1 1 NPS NPS 11967381 11967381 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1kxo NO 1 1 NPS NPS 12823976 12823976 SP says tetramer - PISA says monomer - the protein has been engineered compared to BBP so might not form a tetramer in vitro. An email was sent to the author. Response: 1lnm is definitely a stable monomer (as checked by gel permeation chromatography). 1bbp is rather a dimer according to the biochemical data published by Huber and coworkers. -- Annotation transfered from 1lnm 1kxp_1 PROBNOT 1 1 NPS NPS 12048248 11932258 BU changed since last release and is now corrected - Actin does not form closed dimer - automaticaly inferred from 1lcu 1kxw NO 1 1 NPS NPS 9354379 9354379 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1kxx NO 1 1 NPS NPS 9354379 9354379 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1kxy NO 1 1 NPS NPS 9354379 9354379 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1kxz_1 NO 4 4 D2 D2 12429089 12429089 Paper says: Static light-scattering measurements give a molecular weight of 81 kDa for MT0146/CbiT, compared with a protomer molecular weight of 21 kDa, showing that the protein forms a tetramer in solution. - automatic transfer from 1l3c 1kxz_2 NO 4 4 D2 D2 12429089 12429089 Paper says: Static light-scattering measurements give a molecular weight of 81 kDa for MT0146/CbiT, compared with a protomer molecular weight of 21 kDa, showing that the protein forms a tetramer in solution. - automatic transfer from 1l3c 1ky0 NO 1 1 NPS NPS 12646375 12646375 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1ky1 NO 1 1 NPS NPS 12646375 12646375 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1ky2 PROBNOT 1 1 NPS NPS 11937061 11937061 Ras-related GTPases are small (ca. 20 kDa) monomeric proteins - automatic transfer from 1ky3 1ky3 PROBNOT 1 1 NPS NPS 11937061 11937061 Ras-related GTPases are small (ca. 20 kDa) monomeric proteins 1ky4 NO 4 4 D2 D2 11927587 11927587 SP says tetramer, interface geometry conserved among rat and human. -- Annotation transfered from 1b3r 1ky5 NO 4 4 D2 D2 11927587 11927587 SP says tetramer, interface geometry conserved among rat and human. -- Annotation transfered from 1b3r 1ky8 NO 4 4 D2 D2 11842090 11842090 Paper says tetramer 1kye PROBNOT 2 2 NPS NPS 12437104 12437104 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1kyi NO 24 24 D6 D6 12054822 12054822 1kyn_1 PROBNOT 1 1 NPS NPS 11942800 8896442 Paper says nothing - PISA says monomer - automatic transfer from 1cgh 1kyn_2 PROBNOT 1 1 NPS NPS 11942800 8896442 Paper says nothing - PISA says monomer - automatic transfer from 1cgh 1kyp NO 1 1 NPS NPS 11929238 11929238 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1kyr NO 1 1 NPS NPS 11929238 11929238 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1kys NO 1 1 NPS NPS 11929238 11929238 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1kyv NO 5 5 C5 C5 12083520 12083520 Paper says pentamer -- Annotation transfered from 1kyy 1kyx NO 5 5 C5 C5 12083520 12083520 Paper says pentamer -- Annotation transfered from 1kyy 1kyy NO 5 5 C5 C5 12083520 12083520 Paper says pentamer 1kz1 NO 5 5 C5 C5 12083520 12083520 Paper says pentamer -- Annotation transfered from 1kyy 1kz4 NO 5 5 C5 C5 12083520 12083520 Paper says pentamer -- Annotation transfered from 1kyy 1kz6 NO 5 5 C5 C5 12083520 12083520 Paper says pentamer -- Annotation transfered from 1kyy 1kz8 NO 4 4 D2 D2 12190310 12190310 -- Annotation transfered from 1eyi 1kz9 NO 5 5 C5 C5 12083520 12083520 Paper says pentamer -- Annotation transfered from 1kyy 1kza PROBNOT 2 2 C2 C2 11850428 11850428 The fragment elutes with an apparent molecular weight of 21 kDa from a gel filtration column (data not shown). Since the polypeptide molecular weight is 13 kDa, the elution position suggests that the fragment is dimeric. This conclusion is supported by cross-linking data. -- interesting: I am not sure but read the paper more carefully: seems to undergo a shift in oligomeric state when cutting part of the structure?? -- Annotation transfered from 1rdi 1kzb PROBNOT 2 2 C2 C2 11850428 11850428 The fragment elutes with an apparent molecular weight of 21 kDa from a gel filtration column (data not shown). Since the polypeptide molecular weight is 13 kDa, the elution position suggests that the fragment is dimeric. This conclusion is supported by cross-linking data. -- interesting: I am not sure but read the paper more carefully: seems to undergo a shift in oligomeric state when cutting part of the structure?? -- Annotation transfered from 1rdi 1kzc PROBNOT 2 2 C2 C2 11850428 11850428 The fragment elutes with an apparent molecular weight of 21 kDa from a gel filtration column (data not shown). Since the polypeptide molecular weight is 13 kDa, the elution position suggests that the fragment is dimeric. This conclusion is supported by cross-linking data. -- interesting: I am not sure but read the paper more carefully: seems to undergo a shift in oligomeric state when cutting part of the structure?? -- Annotation transfered from 1rdi 1kzd PROBNOT 2 2 C2 C2 11850428 11850428 The fragment elutes with an apparent molecular weight of 21 kDa from a gel filtration column (data not shown). Since the polypeptide molecular weight is 13 kDa, the elution position suggests that the fragment is dimeric. This conclusion is supported by cross-linking data. -- interesting: I am not sure but read the paper more carefully: seems to undergo a shift in oligomeric state when cutting part of the structure?? -- Annotation transfered from 1rdi 1kze PROBNOT 2 2 C2 C2 11850428 11850428 The fragment elutes with an apparent molecular weight of 21 kDa from a gel filtration column (data not shown). Since the polypeptide molecular weight is 13 kDa, the elution position suggests that the fragment is dimeric. This conclusion is supported by cross-linking data. -- interesting: I am not sure but read the paper more carefully: seems to undergo a shift in oligomeric state when cutting part of the structure?? -- Annotation transfered from 1rdi 1kzf PROBNOT 1 1 NPS NPS 11931774 11931774 Paper says nothing - PISA says monomer -- Annotation transfered from 1k4j 1kzh PROBNOT 2 2 C2 C2 12015149 12015149 Paper says dimer 1kzi NO 2 2 C2 C2 12033935 12033935 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1kzj_1 PROBNOT 2 2 C2 C2 12033935 10648646 BU changed since last release and is now corrected - Clear dimer - automaticaly inferred from 1qqq 1kzj_2 PROBNOT 2 2 C2 C2 12033935 10648646 BU changed since last release and is now corrected - Clear dimer - automaticaly inferred from 1qqq 1kzj_3 PROBNOT 2 2 C2 C2 12033935 10648646 BU changed since last release and is now corrected - Clear dimer - automaticaly inferred from 1qqq 1kzk NO 2 2 C2 C2 11926820 11926820 -- Annotation transfered from 1ajx 1kzl ART 1 3 NPS C3 12377123 12377123 Paper says: In contrast to the homotrimeric solution state of native riboflavin synthase, we found the enzyme to be monomeric in the crystal structure. 1kzm PROBNOT 1 1 NPS NPS 12351824 12351824 SP says monomer -- Annotation transfered from 7atj 1kzz NO 1 1 NPS NPS 12005438 12005438 interface conserved with 1czy (55%) 1l00 NO 1 1 NPS NPS 8460110 8460110 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l01 NO 1 1 NPS NPS 3681997 3681997 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l02 NO 1 1 NPS NPS 3118211 3118211 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l03 NO 1 1 NPS NPS 3118211 3118211 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l04 NO 1 1 NPS NPS 3118211 3118211 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l05 NO 1 1 NPS NPS 3118211 3118211 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l06 NO 1 1 NPS NPS 3118211 3118211 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l07 NO 1 1 NPS NPS 3118211 3118211 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l08 NO 1 1 NPS NPS 3118211 3118211 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l09 NO 1 1 NPS NPS 3118211 3118211 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l0a NO 1 1 NPS NPS 12005438 12005438 interface conserved with 1czy (55%) -- Annotation transfered from 1kzz 1l0d_1 PROBNOT 1 1 NPS NPS 12144785 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1l0d_2 PROBNOT 1 1 NPS NPS 12144785 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1l0e_1 PROBNOT 1 1 NPS NPS 12144785 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1l0e_2 PROBNOT 1 1 NPS NPS 12144785 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1l0f_1 PROBNOT 1 1 NPS NPS 12144785 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1l0f_2 PROBNOT 1 1 NPS NPS 12144785 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1l0g_1 PROBNOT 1 1 NPS NPS 12144785 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1l0g_2 PROBNOT 1 1 NPS NPS 12144785 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1l0j NO 1 1 NPS NPS 12646375 12646375 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l0k NO 1 1 NPS NPS 12646375 12646375 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l0l YES 11 22 NPS C2 12269811 12269811 Interface geometry of the dimerization conserved with 1ezv (37%) 1l0w NO 2 2 C2 C2 11914489 11914489 Interface geometry conserved with 1c0a (48%) -- Annotation transfered from 1g51 1l0x_2 PROBYES 1 4 NPS D2 12015151 9878045 BU changed since last release and is now incorrect - Tetramer might be relevant: Structural and mutational studies of SEB, SEC, SPEA, and TSST1 suggest MHC binding uses the sur face on the front of Domain 1.Since this sur face is blocked in the SPEA tetramer, tetramer–monomer equilibrium will likely modulate superantigenicity. The ability of factors to stabilize the tetramer could be employed to reduce the ability of SPEA to stimulate T-cell proliferation. - automatic transfer from 1ha5_3 1l0x_4 PROBYES 1 4 NPS D2 12015151 9878045 BU changed since last release and is now incorrect - Tetramer might be relevant: Structural and mutational studies of SEB, SEC, SPEA, and TSST1 suggest MHC binding uses the sur face on the front of Domain 1.Since this sur face is blocked in the SPEA tetramer, tetramer–monomer equilibrium will likely modulate superantigenicity. The ability of factors to stabilize the tetramer could be employed to reduce the ability of SPEA to stimulate T-cell proliferation. - automatic transfer from 1ha5_3 1l0y_2 PROBYES 1 4 NPS D2 12015151 9878045 BU changed since last release and is now incorrect - Tetramer might be relevant: Structural and mutational studies of SEB, SEC, SPEA, and TSST1 suggest MHC binding uses the sur face on the front of Domain 1.Since this sur face is blocked in the SPEA tetramer, tetramer–monomer equilibrium will likely modulate superantigenicity. The ability of factors to stabilize the tetramer could be employed to reduce the ability of SPEA to stimulate T-cell proliferation. - automatic transfer from 1ha5_3 1l0y_4 PROBYES 1 4 NPS D2 12015151 9878045 BU changed since last release and is now incorrect - Tetramer might be relevant: Structural and mutational studies of SEB, SEC, SPEA, and TSST1 suggest MHC binding uses the sur face on the front of Domain 1.Since this sur face is blocked in the SPEA tetramer, tetramer–monomer equilibrium will likely modulate superantigenicity. The ability of factors to stabilize the tetramer could be employed to reduce the ability of SPEA to stimulate T-cell proliferation. - automatic transfer from 1ha5_3 1l0z PROBNOT 1 1 NPS NPS 12198297 12198297 -- Annotation transfered from 1c1m 1l10 NO 1 1 NPS NPS 3681997 3681997 Phage T4 lysosyme is monomeric 1l11 NO 1 1 NPS NPS 3118211 3118211 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l12 NO 1 1 NPS NPS 3118211 3118211 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l13 NO 1 1 NPS NPS 3118211 3118211 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l14 NO 1 1 NPS NPS 3118211 3118211 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l15 NO 1 1 NPS NPS 3118211 3118211 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l16 NO 1 1 NPS NPS 3680274 3680274 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l17 NO 1 1 NPS NPS 3405287 3405287 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l18 NO 1 1 NPS NPS 3405287 3405287 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l19 NO 1 1 NPS NPS 3200317 3200317 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l1g PROBNOT 1 1 NPS NPS 12198297 12198297 -- Annotation transfered from 1c1m 1l1q NO 2 2 C2 C2 12171925 12171925 Giardia APRTase is a symmetric homodimer with the monomers built around Rossman fold cores, an element common to all known purine phosphoribosyltransferases. 1l1r NO 2 2 C2 C2 12171925 12171925 Giardia APRTase is a symmetric homodimer with the monomers built around Rossman fold cores, an element common to all known purine phosphoribosyltransferases. -- Annotation transfered from 1l1q 1l1t PROBNOT 1 1 NPS NPS 12055620 12055620 Paper says: DNA glycosylases are relatively small monomeric proteins that do not require cofactors for their activity, -- Annotation transfered from 1r2y 1l1z PROBNOT 1 1 NPS NPS 12055620 12055620 Paper says: DNA glycosylases are relatively small monomeric proteins that do not require cofactors for their activity, -- Annotation transfered from 1r2y 1l20 NO 1 1 NPS NPS 3200317 3200317 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l21 NO 1 1 NPS NPS 2511328 2511328 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l22 NO 1 1 NPS NPS 2511328 2511328 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l23 NO 1 1 NPS NPS 3477797 3477797 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l24 NO 1 1 NPS NPS 3477797 3477797 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l25 NO 1 1 NPS NPS 3277275 3277275 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l26 NO 1 1 NPS NPS 3277275 3277275 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l27 NO 1 1 NPS NPS 3277275 3277275 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l28 NO 1 1 NPS NPS 3277275 3277275 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l29 NO 1 1 NPS NPS 3277275 3277275 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l2b PROBNOT 1 1 NPS NPS 12055620 12055620 Paper says: DNA glycosylases are relatively small monomeric proteins that do not require cofactors for their activity, -- Annotation transfered from 1r2y 1l2c PROBNOT 1 1 NPS NPS 12055620 12055620 Paper says: DNA glycosylases are relatively small monomeric proteins that do not require cofactors for their activity, -- Annotation transfered from 1r2y 1l2d PROBNOT 1 1 NPS NPS 12055620 12055620 Paper says: DNA glycosylases are relatively small monomeric proteins that do not require cofactors for their activity, -- Annotation transfered from 1r2y 1l2e PROBNOT 1 1 NPS NPS 11983703 11983703 1l2h PROBNOT 1 1 NPS NPS 12554939 12554939 SP says monomer -- Annotation transfered from 21bi 1l2i NO 2 2 C2 C2 11953755 11953755 paper says dimer -- Annotation transfered from 1err 1l2j_1 PROBYES 1 2 NPS C2 11953755 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1qkm 1l2j_2 PROBYES 1 2 NPS C2 11953755 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1qkm 1l2s_1 PROBNOT 1 1 NPS NPS 12121656 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1l2s_2 PROBNOT 1 1 NPS NPS 12121656 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1l2t NO 2 2 C2 C2 12150914 12150914 Paper says dimer and shows that it should be the biologicaly relevant one -- ligand induced dimerization 1l2u NO 2 2 C2 C2 12054799 12054799 SP says dimer - interface geometry conserved with 1lor (23%) 1l30 NO 1 1 NPS NPS 3277275 3277275 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l31 NO 1 1 NPS NPS 3277275 3277275 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l32 NO 1 1 NPS NPS 3277275 3277275 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l33 NO 1 1 NPS NPS 2511328 2511328 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l34 NO 1 1 NPS NPS 2665808 2665808 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l35 NO 1 1 NPS NPS 2334683 2334683 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l36 NO 1 1 NPS NPS 1998663 1998663 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l37 NO 1 1 NPS NPS 1854726 1854726 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l38 NO 1 1 NPS NPS 1854726 1854726 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l39 NO 1 1 NPS NPS 1854726 1854726 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l3b_1 NO 4 4 D2 D2 12429089 12429089 Paper says: Static light-scattering measurements give a molecular weight of 81 kDa for MT0146/CbiT, compared with a protomer molecular weight of 21 kDa, showing that the protein forms a tetramer in solution. - automatic transfer from 1l3c 1l3b_2 NO 4 4 D2 D2 12429089 12429089 Paper says: Static light-scattering measurements give a molecular weight of 81 kDa for MT0146/CbiT, compared with a protomer molecular weight of 21 kDa, showing that the protein forms a tetramer in solution. - automatic transfer from 1l3c 1l3c NO 4 4 D2 D2 12429089 12429089 Paper says: Static light-scattering measurements give a molecular weight of 81 kDa for MT0146/CbiT, compared with a protomer molecular weight of 21 kDa, showing that the protein forms a tetramer in solution. 1l3f PROBNOT 1 1 NPS NPS 12037302 12037302 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1l3i_1 NO 4 4 D2 D2 12429089 12429089 Paper says: Static light-scattering measurements give a molecular weight of 81 kDa for MT0146/CbiT, compared with a protomer molecular weight of 21 kDa, showing that the protein forms a tetramer in solution. - automatic transfer from 1l3c 1l3i_2 NO 4 4 D2 D2 12429089 12429089 Paper says: Static light-scattering measurements give a molecular weight of 81 kDa for MT0146/CbiT, compared with a protomer molecular weight of 21 kDa, showing that the protein forms a tetramer in solution. - automatic transfer from 1l3c 1l3j PROBNOT 6 6 D3 D3 12056897 12056897 Paper says hexamer - Interesting because it says that trimeric homologs also exist although they are not in PDB: The three proteins phaseolin, canavalin, and proglycinin are all classified as seed storage proteins. These seed storage proteins are trimeric bicupins with no metal binding sites but share some features of quaternary structure with the hexameric bicupin OXDC. -- SCOP dom_arch Error (2 doms) -- VERY interesting example of sequencial evolution: 1 domain, duplication (fusion) --> bi-domain, trimerization, and hexamerization. **** 1l3l_1 PROBYES 2 2 C2 NS 12087407 12198141 BU changed since last release and is now incorrect - Paper says: The structure reveals an asymmetric homodimer, with one monomer longer than the other. - automatic transfer from 1h0m_1 1l3l_2 PROBYES 2 2 C2 NS 12087407 12198141 BU changed since last release and is now incorrect - Paper says: The structure reveals an asymmetric homodimer, with one monomer longer than the other. - automatic transfer from 1h0m_1 1l3r NO 1 1 NPS NPS 11896404 11896404 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1l40 NO 1 1 NPS NPS 1854726 1854726 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l41 NO 1 1 NPS NPS 1854726 1854726 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l42 NO 1 1 NPS NPS 1942034 1942034 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l43 NO 1 1 NPS NPS 1942034 1942034 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l44 NO 1 1 NPS NPS 1942034 1942034 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l45 NO 1 1 NPS NPS 1942034 1942034 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l46 NO 1 1 NPS NPS 1942034 1942034 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l47 NO 1 1 NPS NPS 1942034 1942034 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l48 NO 1 1 NPS NPS 1920439 1920439 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l49 NO 1 1 NPS NPS 1920439 1920439 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l4d PROBNOT 2 2 NPS NPS 12456874 12456874 cf. 1bml 1l4i PROBNOT 2 2 NS NS 12037304 12037304 Paper proposes that the dimerization acts as a capping of the interaction surface. It exists in a monomer-dimer equilibrium 1l4u PROBNOT 1 1 NPS NPS 12054870 12054870 SP says monomer 1l4y PROBNOT 1 1 NPS NPS 12054870 12054870 SP says monomer -- Annotation transfered from 1l4u 1l4z PROBNOT 2 2 NPS NPS 12456874 12456874 cf. 1bml -- Annotation transfered from 1l4d 1l50 NO 1 1 NPS NPS 1920439 1920439 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l51 NO 1 1 NPS NPS 1920439 1920439 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l52 NO 1 1 NPS NPS 1920439 1920439 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l53 NO 1 1 NPS NPS 1920439 1920439 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l54 NO 1 1 NPS NPS 1747370 1747370 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l55 NO 1 1 NPS NPS 1911773 1911773 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l56 NO 1 1 NPS NPS 1457724 1457724 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l57 NO 1 1 NPS NPS 1911773 1911773 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l58 NO 1 1 NPS NPS 0 0 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l59 NO 1 1 NPS NPS 1911773 1911773 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l5b NO 2 2 C2 C2 12015150 12015150 Domain swapped dimer 1l5q YES 4 2 NS C2 12204691 12204691 -- Annotation transfered from 1l7x 1l5r YES 4 2 NS C2 12204691 12204691 -- Annotation transfered from 1l7x 1l5s YES 4 2 NS C2 12204691 12204691 -- Annotation transfered from 1l7x 1l5v NO 2 2 C2 C2 12217700 12217700 -- Annotation transfered from 2ecp 1l5w NO 2 2 C2 C2 12217700 12217700 -- Annotation transfered from 2ecp 1l5y YES 2 2 C2 C2 12368235 12368235 Wrong interface used for reconstruction - interesting example for paper 1l5z NO 2 2 C2 C2 12368235 12368235 Paper says dimer -- Annotation transfered from 1qkk 1l60 NO 1 1 NPS NPS 1457724 1457724 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l61 NO 1 1 NPS NPS 1911773 1911773 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l62 NO 1 1 NPS NPS 1911773 1911773 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l63 NO 1 1 NPS NPS 1911773 1911773 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l64 NO 1 1 NPS NPS 1570293 1570293 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l65 NO 1 1 NPS NPS 1570293 1570293 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l66 NO 1 1 NPS NPS 1570293 1570293 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l67 NO 1 1 NPS NPS 1570293 1570293 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l68 NO 1 1 NPS NPS 1570293 1570293 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l69 NO 1 1 NPS NPS 1304917 1304917 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l6i NO 2 2 C2 C2 12217700 12217700 -- Annotation transfered from 2ecp 1l6j PROBNOT 1 1 NPS NPS 12077439 12077439 Paper says: 80 mg of pure monomeric pMMP9 was pooled based upon purity as judged by SDS-PAGE - not very convincing ... PISA also says monomeric 1l6m_1 PROBNOT 1 1 NPS NPS 12453412 10684642 BU changed since last release and is now corrected - Neutrophil gelatinase associated lipocalin (NGAL), a member of the lipocalin family, is released from neutrophil granules as a 25 kDa monomer, a 46 kDa disulfide-linked homodimer, and a disulfide-linked heterodimer with gelatinase B (matrix metalloproteinase 9) - this one is not linked by a S-S bond. - automaticaly inferred from 1qqs 1l6m_2 PROBNOT 1 1 NPS NPS 12453412 10684642 BU changed since last release and is now corrected - Neutrophil gelatinase associated lipocalin (NGAL), a member of the lipocalin family, is released from neutrophil granules as a 25 kDa monomer, a 46 kDa disulfide-linked homodimer, and a disulfide-linked heterodimer with gelatinase B (matrix metalloproteinase 9) - this one is not linked by a S-S bond. - automaticaly inferred from 1qqs 1l6m_3 PROBNOT 1 1 NPS NPS 12453412 10684642 BU changed since last release and is now corrected - Neutrophil gelatinase associated lipocalin (NGAL), a member of the lipocalin family, is released from neutrophil granules as a 25 kDa monomer, a 46 kDa disulfide-linked homodimer, and a disulfide-linked heterodimer with gelatinase B (matrix metalloproteinase 9) - this one is not linked by a S-S bond. - automaticaly inferred from 1qqs 1l6s NO 8 8 D4 D4 11909869 11909869 Paper says octamer -- Annotation transfered from 1i8j 1l6y NO 8 8 D4 D4 11909869 11909869 Paper says octamer -- Annotation transfered from 1i8j 1l6z PROBNOT 1 1 NPS NPS 11980704 11980704 Paper says nothing about an oligomer, PISA says monomer 1l70 NO 1 1 NPS NPS 1304917 1304917 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l71 NO 1 1 NPS NPS 1304917 1304917 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l72 NO 1 1 NPS NPS 1304917 1304917 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l73 NO 1 1 NPS NPS 1304917 1304917 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l74 NO 1 1 NPS NPS 1304917 1304917 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l75 NO 1 1 NPS NPS 1304917 1304917 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l76 NO 1 1 NPS NPS 1733941 1733941 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l77 NO 1 1 NPS NPS 1569571 1569571 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l79 NO 1 1 NPS NPS 1569571 1569571 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l7a NO 6 6 D3 D3 0 0 1l7x YES 4 2 NS C2 12204691 12204691 1l7z PROBNOT 1 1 NPS NPS 14765114 14765114 -- Annotation transfered from 3cln 1l80 NO 1 1 NPS NPS 1569571 1569571 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l81 NO 1 1 NPS NPS 1569571 1569571 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l82 NO 1 1 NPS NPS 1569571 1569571 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l83 NO 1 1 NPS NPS 1731252 1731252 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l84 NO 1 1 NPS NPS 1731252 1731252 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l85 NO 1 1 NPS NPS 8433369 8433369 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l86 NO 1 1 NPS NPS 8433369 8433369 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l87 NO 1 1 NPS NPS 8433369 8433369 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l88 NO 1 1 NPS NPS 8433369 8433369 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l89 NO 1 1 NPS NPS 8433369 8433369 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l8g PROBNOT 1 1 NPS NPS 11732900 11732900 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1l8h NO 12 12 Tetr Tetr 0 0 Interface geometry conserved with 1o9r (55%) -- Annotation transfered from 1dps 1l8i NO 12 12 Tetr Tetr 0 0 Interface geometry conserved with 1o9r (55%) -- Annotation transfered from 1dps 1l8k PROBNOT 1 1 NPS NPS 11907034 11907034 Paper says monomer -- very interesting: a dimer exists and is linked to an inhibition of the receptor: PID = 8700232 1l8n NO 2 2 C2 C2 14573597 14573597 Homodimer -- Annotation transfered from 1mqq 1l8p_1 NO 2 2 C2 C2 12054465 8605183 Interface conserved with 1te6 (62% id) -- Annotation transfered from 1one 1l8p_2 NO 2 2 C2 C2 12054465 8605183 Interface conserved with 1te6 (62% id) -- Annotation transfered from 1one 1l8s PROBNOT 2 2 C2 C2 12475227 12475227 Papers of identical structures speak about the dimer as something relevant but it is interesting to note that two modes of dimerization exist among these proteins. I have not seen this discussed -- Annotation transfered from 1fx9 1l90 NO 1 1 NPS NPS 8433369 8433369 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l91 NO 1 1 NPS NPS 8433369 8433369 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l92 NO 1 1 NPS NPS 8433369 8433369 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l93 NO 1 1 NPS NPS 8433369 8433369 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l94 NO 1 1 NPS NPS 8433369 8433369 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l95 NO 1 1 NPS NPS 8433369 8433369 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l96 NO 1 1 NPS NPS 1404394 1404394 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l97_1 NO 1 1 NPS NPS 1404394 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1l97_2 NO 1 1 NPS NPS 1404394 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1l98 NO 1 1 NPS NPS 8460110 8460110 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l99 NO 1 1 NPS NPS 8460110 8460110 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1l9m YES 2 1 NS NPS 11980702 11980702 Paper says: the protein is a monomer in solution 1l9n YES 2 1 NS NPS 11980702 11980702 Paper says: the protein is a monomer in solution -- Annotation transfered from 1l9m 1l9o NO 3 3 C3 C3 12538888 12538888 -- Annotation transfered from 1as7 1l9p NO 3 3 C3 C3 12538888 12538888 -- Annotation transfered from 1as7 1l9q NO 3 3 C3 C3 12538888 12538888 -- Annotation transfered from 1as7 1l9r NO 3 3 C3 C3 12538888 12538888 -- Annotation transfered from 1as7 1l9s NO 3 3 C3 C3 12538888 12538888 -- Annotation transfered from 1as7 1l9t NO 3 3 C3 C3 12538888 12538888 -- Annotation transfered from 1as7 1l9v YES 1 8 NPS D4 12015608 12015608 Paper sys protein functional as an octamer 1la2 NO 4 4 D2 D2 12836703 12836703 MIP synthase is a homotetramer both in solution and in the solid state -- Annotation transfered from 1jki 1laa NO 1 1 NPS NPS 1363898 1363898 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1laf PROBNOT 1 1 NPS NPS 7929349 7929349 Both papers do not mention a dimer - PISA says monomer -- Annotation transfered from 1lag 1lag PROBNOT 1 1 NPS NPS 7929349 7929349 Both papers do not mention a dimer - PISA says monomer 1lah PROBNOT 1 1 NPS NPS 7929349 7929349 Both papers do not mention a dimer - PISA says monomer -- Annotation transfered from 1lag 1lam NO 6 6 D3 D3 7578088 7578088 Interface geometry conserved with 1gyt (30%) -- Annotation transfered from 1bll 1lan NO 6 6 D3 D3 7578088 7578088 Interface geometry conserved with 1gyt (30%) -- Annotation transfered from 1bll 1lap NO 6 6 D3 D3 2395881 2395881 Interface geometry conserved with 1gyt (30%) -- Annotation transfered from 1bll 1lat YES 2 2 C2 NA 7664096 7664096 BU changed since last release and is now incorrect - The two proteins bind distinct binding sites on the DNA 1lav PROBNOT 1 1 NPS NPS 8390295 8390295 SP says monomer -- Annotation transfered from 1f21 1law PROBNOT 1 1 NPS NPS 8390295 8390295 SP says monomer -- Annotation transfered from 1f21 1lax_1 PROBNOT 1 1 NPS NPS 12592028 12794084 EcoCyc says monomer - automatic transfer from 1nl5 1lax_2 PROBNOT 1 1 NPS NPS 12592028 12794084 EcoCyc says monomer - automatic transfer from 1nl5 1lb3 NO 24 24 Octa Octa 12459904 12459904 Interface geometry conserved with 1ies (80%) 1lb8_1 YES 1 2 NPS C2 12015593 12015593 Paper says dimer (and shows it) - automatic transfer from 1lbb 1lb8_2 YES 1 2 NPS C2 12015593 12015593 Paper says dimer (and shows it) - automatic transfer from 1lbb 1lb9_1 YES 1 2 NPS C2 12015593 12015593 Paper says dimer (and shows it) - automatic transfer from 1lbb 1lb9_2 YES 1 2 NPS C2 12015593 12015593 Paper says dimer (and shows it) - automatic transfer from 1lbb 1lbb YES 1 2 NPS C2 12015593 12015593 Paper says dimer (and shows it) 1lbc_1 YES 1 2 NPS C2 12015593 12015593 Paper says dimer (and shows it) - automatic transfer from 1lbb 1lbc_2 YES 1 2 NPS C2 12015593 12015593 Paper says dimer (and shows it) - automatic transfer from 1lbb 1lbc_3 YES 1 2 NPS C2 12015593 12015593 Paper says dimer (and shows it) - automatic transfer from 1lbb 1lbd NO 2 2 C2 C2 7760929 7760929 Paper says dimer 1lbh NO 4 4 C2 C2 8638105 8638105 1lbi NO 4 4 C2 C2 8638105 8638105 -- Annotation transfered from 1lbh 1lbk NO 2 2 C2 C2 12473455 12473455 -- Annotation transfered from 9gss 1lbm YES 1 2 NPS C2 12356303 12356303 Interface conseved with 1v5x (42%) 1lbv NO 2 2 C2 C2 11940584 11940584 -- Annotation transfered from 1lbx 1lbw NO 2 2 C2 C2 11940584 11940584 -- Annotation transfered from 1lbx 1lbx NO 2 2 C2 C2 11940584 11940584 1lby NO 2 2 C2 C2 11940584 11940584 -- Annotation transfered from 1lbx 1lbz NO 2 2 C2 C2 11940584 11940584 -- Annotation transfered from 1lbx 1lc0 NO 1 1 NPS NPS 12079357 12079357 Paper says: Structurally related proteins utilize this C-terminal sheet in forming oligomeric proteins. In BVR, however, the sheet is fully exposed to a solvent channel in the crystal lattice and the residues comprising the sheet are poorly conserved, consistent with dynamic light-scattering experiments indicating that BVR is monomeric. 1lc3 NO 1 1 NPS NPS 12079357 12079357 Paper says: Structurally related proteins utilize this C-terminal sheet in forming oligomeric proteins. In BVR, however, the sheet is fully exposed to a solvent channel in the crystal lattice and the residues comprising the sheet are poorly conserved, consistent with dynamic light-scattering experiments indicating that BVR is monomeric. -- Annotation transfered from 1lc0 1lc5 NO 2 2 C2 C2 12119022 12119022 -- Annotation transfered from 1lc7 1lc7 NO 2 2 C2 C2 12119022 12119022 1lc8 NO 2 2 C2 C2 12119022 12119022 -- Annotation transfered from 1lc7 1lca NO 2 2 C2 C2 8371269 8371269 SP says homodimer -- Annotation transfered from 4tms 1lcb NO 2 2 C2 C2 8371269 8371269 SP says homodimer -- Annotation transfered from 4tms 1lce NO 2 2 C2 C2 8371269 8371269 SP says homodimer -- Annotation transfered from 4tms 1lci NO 1 1 NPS NPS 8805533 8805533 Paper says: the luciferase enzyme from the North American firefly Photinus pyralis was obtained from Promega as a 61-kDa recombinant monomeric protein. -- Annotation transfered from 1ba3 1lcj PROBNOT 1 1 NPS NPS 7680435 7680435 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 -- Annotation transfered from 1lkk 1lcl NO 2 2 C2 C2 8747464 8747464 Forms crystals in vivo, that is why I consider this interaction relevant. 1lcn_1 NO 1 1 NPS NPS 11418760 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1lcn_2 NO 1 1 NPS NPS 11418760 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1lco NO 4 4 C2 C4 7632684 2329585 The structure is a cyclic tetramer but only C2 is detected because two small domain (out of the four) are unfolded and not visible. -- Annotation transfered from 1fcb 1lcp NO 6 6 D3 D3 7619821 7619821 Interface geometry conserved with 1gyt (30%) -- Annotation transfered from 1bll 1lcu YES 2 1 C2 NPS 11932258 11932258 Actin does not form closed dimer 1lcv NO 4 4 D2 D2 12055191 12055191 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1lcw NO 4 4 D2 D2 12055191 12055191 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1lcy YES 1 3 NPS C3 11967569 11967569 Interface geometry conserved with 1sot 1lcz NO 4 4 D2 D2 12055191 12055191 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1lda NO 4 4 C4 C4 11964478 11964478 Paper says tetramer -- Annotation transfered from 1ldi 1ldb YES 4 7 D2 D2 2330370 2330370 BU changed since last release and is now incorrect - Paper, SP say tetramer -- Annotation transfered from 2ldb 1ldc NO 4 4 C2 C4 7632684 2329585 The structure is a cyclic tetramer but only C2 is detected because two small domain (out of the four) are unfolded and not visible. -- Annotation transfered from 1fcb 1lde YES 4 2 NS C2 9132002 9132002 1ldf NO 4 4 C4 C4 11964478 11964478 Paper says tetramer -- Annotation transfered from 1ldi 1ldg NO 4 4 D2 D2 8901865 8901865 SP says tetramer 1ldi NO 4 4 C4 C4 11964478 11964478 Paper says tetramer 1ldm PROBNOT 4 4 D2 D2 3430615 3430615 Tight tetramer, PISA agrees. -- 8ldh is strange though: less contacts than the others (1ldm). Why is that? Check - possible error/bug -- Annotation transfered from 8ldh 1ldn_1 NO 4 4 D2 D2 1731077 2330370 BU changed since last release and is now corrected - Paper, SP say tetramer - automatic transfer from 2ldb 1ldn_2 NO 4 4 D2 D2 1731077 2330370 BU changed since last release and is now corrected - Paper, SP say tetramer - automatic transfer from 2ldb 1ldo NO 4 4 D2 D2 12055191 12055191 Avidin is a clear tetramer -- Annotation transfered from 2cam 1ldq NO 4 4 D2 D2 12055191 12055191 Avidin is a clear tetramer -- Annotation transfered from 2cam 1ldy_1 PROBNOT 2 2 C2 C2 9132002 9132002 BU changed since last release and is now corrected - - automaticaly inferred from 1lde 1ldy_2 PROBNOT 2 2 C2 C2 9132002 9132002 BU changed since last release and is now corrected - - automaticaly inferred from 1lde 1lec NO 2 2 C2 C2 8478943 8478943 the quaternary structure of the molecular dimer is different from that of any other lectin reported to date 1led NO 2 2 C2 C2 8478943 8478943 the quaternary structure of the molecular dimer is different from that of any other lectin reported to date -- Annotation transfered from 1lec 1lel NO 4 4 D2 D2 12055191 12055191 Avidin is a clear tetramer -- Annotation transfered from 2cam 1leo NO 6 6 D3 D3 8702707 8702707 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1lev NO 4 4 D2 D2 12781194 12781194 -- Annotation transfered from 1eyi 1lew PROBNOT 1 1 NPS NPS 12086621 12086621 -- Annotation transfered from 1kv1 1lez PROBNOT 1 1 NPS NPS 12086621 12086621 -- Annotation transfered from 1kv1 1lf0 NO 1 1 NPS NPS 12213964 12213964 Ras proteins are monomeric G proteins -- Annotation transfered from 1ctq 1lf5 NO 1 1 NPS NPS 12213964 12213964 Ras proteins are monomeric G proteins -- Annotation transfered from 1ctq 1lf7 PROBNOT 1 1 NPS NPS 12033936 12033936 Heterocomplex but not homo apparently: C8 is disulfide-linked to a C8 subunit that is noncovalently associated with a C8 chain. 1lfa PROBYES 2 1 C2 NPS 7479767 7479767 Interface very small - probably monomer 1lfm_1 PROBNOT 1 1 NPS NPS 12084923 0 - automatic transfer from 5cyt 1lfm_2 PROBNOT 1 1 NPS NPS 12084923 0 - automatic transfer from 5cyt 1lfo PROBNOT 1 1 NPS NPS 9054409 9054409 Paper says nothing, PISA says monomer 1lg1 NO 1 1 NPS NPS 11960986 11960986 Monomer: paper says: the enzyme occurs in two major forms of 39 and 50 kDa. The subsequent cloning of its cDNA from a macrophage library showed that the 50-kDa form can be converted to the 39-kDa form post-translationally or by RNA processing -- Annotation transfered from 1hki 1lg2 NO 1 1 NPS NPS 11960986 11960986 Monomer: paper says: the enzyme occurs in two major forms of 39 and 50 kDa. The subsequent cloning of its cDNA from a macrophage library showed that the 50-kDa form can be converted to the 39-kDa form post-translationally or by RNA processing -- Annotation transfered from 1hki 1lg5 PROBNOT 1 1 NPS NPS 12056894 12056894 9000633 says monomeric -- Annotation transfered from 1uga 1lg6 PROBNOT 1 1 NPS NPS 12056894 12056894 9000633 says monomeric -- Annotation transfered from 1uga 1lgd PROBNOT 1 1 NPS NPS 12056894 12056894 9000633 says monomeric -- Annotation transfered from 1uga 1lgr NO 12 12 D6 D6 7727369 7727369 BU changed since last release and is now corrected - Salmonella typhimurium GS has a molecular mass of 620 kDa and is a dodecamer with 622 symmetry 1lgt NO 8 8 D4 D4 12415290 12415290 Interface geometry conserved with 1kw6 (66%) -- Annotation transfered from 1knf 1lgu NO 1 1 NPS NPS 12217695 12217695 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1lgv NO 2 2 C2 C2 12720277 12720277 -- Annotation transfered from 1jvk 1lgw NO 1 1 NPS NPS 12217695 12217695 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1lgx NO 1 1 NPS NPS 12217695 12217695 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1lh1 PROBNOT 1 1 NPS NPS -1 0 SP says monomer -- Annotation transfered from 2gdm 1lh2 PROBNOT 1 1 NPS NPS -1 0 SP says monomer -- Annotation transfered from 2gdm 1lh3 PROBNOT 1 1 NPS NPS -1 0 SP says monomer -- Annotation transfered from 2gdm 1lh5 PROBNOT 1 1 NPS NPS -1 0 SP says monomer -- Annotation transfered from 2gdm 1lh6 PROBNOT 1 1 NPS NPS -1 0 SP says monomer -- Annotation transfered from 2gdm 1lh7 PROBNOT 1 1 NPS NPS -1 0 SP says monomer -- Annotation transfered from 2gdm 1lhh NO 1 1 NPS NPS 1643041 1643041 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1lhi NO 1 1 NPS NPS 1643041 1643041 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1lhj NO 1 1 NPS NPS 1643041 0 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1lhk NO 1 1 NPS NPS 1643041 1643041 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1lhl NO 1 1 NPS NPS 1643041 1643041 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1lhm NO 1 1 NPS NPS 2061330 2061330 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1lhp NO 2 2 C2 C2 12235162 12235162 Interface geometry conserved with 1ub0 (31%) -- Annotation transfered from 1lhr 1lhr NO 2 2 C2 C2 12235162 12235162 Interface geometry conserved with 1ub0 (31%) 1lhs NO 1 1 NPS NPS 7714901 7714901 Myoglobin is monomeric -- Annotation transfered from 1lht 1lht NO 1 1 NPS NPS 7714901 7714901 Myoglobin is monomeric 1lhy PROBNOT 1 1 NPS NPS 12058046 12058046 EcoCyc says monomer -- Annotation transfered from 1jwp 1lhz NO 2 2 C2 C2 12720277 12720277 -- Annotation transfered from 1jvk 1li0 PROBNOT 1 1 NPS NPS 12058046 12058046 EcoCyc says monomer -- Annotation transfered from 1jwp 1li2 NO 1 1 NPS NPS 12217695 12217695 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1li3 NO 1 1 NPS NPS 12217695 12217695 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1li4 NO 4 4 D2 D2 12590576 12590576 SP says tetramer, interface geometry conserved among rat and human. -- Annotation transfered from 1b3r 1li6 NO 1 1 NPS NPS 12217695 12217695 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1li9 PROBNOT 1 1 NPS NPS 12058046 12058046 EcoCyc says monomer -- Annotation transfered from 1jwp 1lib PROBYES 2 1 C2 NPS 8463311 8463311 ALBP is monomeric at low and high salt concentrations. -- Annotation transfered from 1ab0 1lic PROBYES 2 1 C2 NPS 8161548 8161548 ALBP is monomeric at low and high salt concentrations. -- Annotation transfered from 1ab0 1lid PROBYES 2 1 C2 NPS 8463311 8463311 ALBP is monomeric at low and high salt concentrations. -- Annotation transfered from 1ab0 1lie PROBYES 2 1 C2 NPS 8161548 8161548 ALBP is monomeric at low and high salt concentrations. -- Annotation transfered from 1ab0 1lif PROBYES 2 1 C2 NPS 8463311 8463311 ALBP is monomeric at low and high salt concentrations. -- Annotation transfered from 1ab0 1lih YES 1 2 NPS C2 1660187 1660187 dimeric -- Annotation transfered from 1was 1lil PROBNOT 2 2 C2 C2 15299564 0 1lin PROBNOT 1 1 NPS NPS 7634090 7634090 -- Annotation transfered from 3cln 1lis PROBNOT 1 1 NPS NPS 8266073 8266073 Monomerization of the lysin dimer exposes the hydrophobic patch and allows it to interact with the VE glycoproteins. 1lit PROBNOT 1 1 NPS NPS 8654365 8654365 Paper implies monomeric -- Annotation transfered from 1qdd 1lj1_1 PROBNOT 1 1 NPS NPS 12356299 10581550 SP says monomer - automatic transfer from 1qjd 1lj1_2 PROBNOT 1 1 NPS NPS 12356299 10581550 SP says monomer - automatic transfer from 1qjd 1lj3_1 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1lj3_2 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1lj4_1 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1lj4_2 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1lj5 PROBNOT 1 1 NPS NPS 0 0 Paper says nothing - Family mostly monomeric - PISA says monomer -- Annotation transfered from 1dvn 1lje_1 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1lje_2 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1ljf_1 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1ljf_2 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1ljg_1 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1ljg_2 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1ljh_1 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1ljh_2 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1lji_1 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1lji_2 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1ljj_1 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1ljj_2 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1ljk_1 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1ljk_2 NO 1 1 NPS NPS 12077436 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1ljn NO 1 1 NPS NPS 12012337 12012337 -- Annotation transfered from 135l 1ljr NO 2 2 C2 C2 9551553 9551553 Interface geometry conserved with 1e6b (27%) 1ljy NO 1 1 NPS NPS 12529329 12529329 Elutes as a monomer - Papers says: The second peak in this final chromatographic step corresponded to a molecular mass of 40 kDa. 1lk5 NO 4 4 D2 D2 12057201 12057201 Paper says: PRI is a tetramer in the crystal and in solution 1lk6 PROBNOT 2 2 C2 C2 12578831 12578831 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization -- Annotation transfered from 1jvq 1lk7 NO 4 4 D2 D2 12057201 12057201 Paper says: PRI is a tetramer in the crystal and in solution -- Annotation transfered from 1lk5 1lka PROBNOT 1 1 NPS NPS 12198296 12198296 -- Annotation transfered from 1c1m 1lkb PROBNOT 1 1 NPS NPS 12198296 12198296 -- Annotation transfered from 1c1m 1lkc NO 2 2 C2 C2 11939774 11939774 -- Annotation transfered from 1lc7 1lkd NO 8 8 D4 D4 12415290 12415290 Interface geometry conserved with 1kw6 (66%) -- Annotation transfered from 1knf 1lke NO 1 1 NPS NPS 12823976 12823976 SP says tetramer - PISA says monomer - the protein has been engineered compared to BBP so might not form a tetramer in vitro. An email was sent to the author. Response: 1lnm is definitely a stable monomer (as checked by gel permeation chromatography). 1bbp is rather a dimer according to the biochemical data published by Huber and coworkers. -- Annotation transfered from 1lnm 1lkk PROBNOT 1 1 NPS NPS 8604142 8604142 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1lkl PROBNOT 1 1 NPS NPS 8604142 8604142 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 -- Annotation transfered from 1lkk 1lkm NO 2 2 C2 C2 12175244 12175244 1lko NO 2 2 C2 C2 12175244 12175244 -- Annotation transfered from 1lkm 1lkp NO 2 2 C2 C2 12175244 12175244 -- Annotation transfered from 1lkm 1lkr_1 NO 1 1 NPS NPS 9757091 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1lkr_2 NO 1 1 NPS NPS 9757091 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1lks NO 1 1 NPS NPS 9757091 9757091 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lkv NO 1 1 NPS NPS 12093724 12093724 1lkz NO 2 2 C2 C2 12211039 12211039 Interface geometry conserved with 1uj6 (40%) 1ll1 NO 6 6 D3 D3 0 0 Interface geometry conserved with 1hcy (35%) 1ll4_1 PROBNOT 1 1 NPS NPS 12079386 10752616 Paper says nothing about oligomeric state, PISA says monomer - automatic transfer from 1d2k 1ll4_2 PROBNOT 1 1 NPS NPS 12079386 10752616 Paper says nothing about oligomeric state, PISA says monomer - automatic transfer from 1d2k 1ll4_3 PROBNOT 1 1 NPS NPS 12079386 10752616 Paper says nothing about oligomeric state, PISA says monomer - automatic transfer from 1d2k 1ll4_4 PROBNOT 1 1 NPS NPS 12079386 10752616 Paper says nothing about oligomeric state, PISA says monomer - automatic transfer from 1d2k 1ll5_1 PROBNOT 1 1 NPS NPS 12435704 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1ll5_2 PROBNOT 1 1 NPS NPS 12435704 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1ll6_1 PROBNOT 1 1 NPS NPS 12079386 10752616 Paper says nothing about oligomeric state, PISA says monomer - automatic transfer from 1d2k 1ll6_2 PROBNOT 1 1 NPS NPS 12079386 10752616 Paper says nothing about oligomeric state, PISA says monomer - automatic transfer from 1d2k 1ll6_3 PROBNOT 1 1 NPS NPS 12079386 10752616 Paper says nothing about oligomeric state, PISA says monomer - automatic transfer from 1d2k 1ll6_4 PROBNOT 1 1 NPS NPS 12079386 10752616 Paper says nothing about oligomeric state, PISA says monomer - automatic transfer from 1d2k 1ll7_1 PROBNOT 1 1 NPS NPS 12079386 10752616 Paper says nothing about oligomeric state, PISA says monomer - automatic transfer from 1d2k 1ll7_2 PROBNOT 1 1 NPS NPS 12079386 10752616 Paper says nothing about oligomeric state, PISA says monomer - automatic transfer from 1d2k 1ll9_1 PROBNOT 1 1 NPS NPS 12323371 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1ll9_2 PROBNOT 1 1 NPS NPS 12323371 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1lla PROBYES 1 6 NPS D3 8518732 8518732 Paper says hexamer -- PISA doesnt find it 1llb_1 PROBNOT 1 1 NPS NPS 12323371 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1llb_2 PROBNOT 1 1 NPS NPS 12323371 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1llc PROBNOT 4 4 D2 D2 -1 0 SP says tetramer - Paper not available - looks like a tight tetramer but PISA says dimer? Error? 1lld NO 4 4 D2 D2 8450537 8450537 Paper says tetramer 1llf NO 2 2 C2 C2 12499539 12499539 Paper says homodimer 1llh NO 1 1 NPS NPS 11847274 11847274 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1lln PROBNOT 1 1 NPS NPS 12754107 12754107 1llo PROBNOT 1 1 NPS NPS 7495789 7495789 -- Annotation transfered from 1kr1 1lls PROBNOT 1 1 NPS NPS 12217701 12217701 EcoCyc says monomer -- Annotation transfered from 1nl5 1llt PROBNOT 1 1 NPS NPS 12960334 12960334 Abs detected, besides a Bet v 1 monomer of 17 kDa, a dimer of 34 kDa. In dynamic light scattering, Bet v 1 appeared as dimers and even multimers, but a single condition could be defined where it behaved exclusively monomerically - monomer dimer equilibrium - interesting -- Annotation transfered from 1fm4 1llu_1 NO 4 4 D2 D2 15152088 15152088 BU changed since last release and is now corrected - Paper says tetramer 1llu_2 NO 4 4 D2 D2 15152088 15152088 BU changed since last release and is now corrected - Paper says tetramer 1lm3 PROBYES 2 1 C2 NPS 11914078 11914078 SP, EcoCyc, PISA say monomer 1lm4_1 PROBNOT 1 1 NPS NPS 12823970 15382235 Paper implies monomer - related protein are monomeric and PISA says monomer - automatic transfer from 1q1y 1lm4_2 PROBNOT 1 1 NPS NPS 12823970 15382235 Paper implies monomer - related protein are monomeric and PISA says monomer - automatic transfer from 1q1y 1lm5 PROBYES 2 1 NS NPS 12101406 12101406 Small domain of a >2000aa protein. The protein normally forms homodimers but through coiled coil. 1lm6 PROBNOT 1 1 NPS NPS 12823970 12823970 Paper says nothing - Related proteins are monomeric and PISA says monomer 1lm7 PROBYES 2 1 C2 NPS 12101406 12101406 Small domain of a >2000aa protein. The protein normally forms homodimers but through coiled coil. 1lma NO 1 1 NPS NPS 15299529 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lmc NO 1 1 NPS NPS 15299732 0 -- Annotation transfered from 1lmq 1lmh PROBNOT 1 1 NPS NPS 12048187 12048187 Paper implies monomer - related protein are monomeric and PISA says monomer -- Annotation transfered from 1q1y 1lmn NO 1 1 NPS NPS 15299303 0 -- Annotation transfered from 1lmq 1lmo NO 1 1 NPS NPS 15299765 0 -- Annotation transfered from 1lmq 1lmp NO 1 1 NPS NPS 15299765 0 -- Annotation transfered from 1lmq 1lmq NO 1 1 NPS NPS 15299765 0 1lmt NO 1 1 NPS NPS 7890692 7890692 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ln8 PROBNOT 1 1 NPS NPS 0 0 Paper says nothing about oligomer - PISA says monomer -- Annotation transfered from 1td7 1lna PROBNOT 2 2 C2 C2 8535232 8535232 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 8tln 1lnb PROBNOT 2 2 C2 C2 8535232 8535232 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 8tln 1lnc PROBNOT 2 2 C2 C2 8535232 8535232 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 8tln 1lnd PROBNOT 2 2 C2 C2 8535232 8535232 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 8tln 1lne PROBNOT 2 2 C2 C2 8535232 8535232 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 8tln 1lnf PROBNOT 2 2 C2 C2 8535232 8535232 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 8tln 1lni_1 PROBNOT 1 1 NPS NPS 12136142 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1lni_2 PROBNOT 1 1 NPS NPS 12136142 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1lnm NO 1 1 NPS NPS 12823976 12823976 SP says tetramer - PISA says monomer - the protein has been engineered compared to BBP so might not form a tetramer in vitro. An email was sent to the author. Response: 1lnm is definitely a stable monomer (as checked by gel permeation chromatography). 1bbp is rather a dimer according to the biochemical data published by Huber and coworkers. 1lo6 PROBNOT 1 1 NPS NPS 0 0 -- Annotation transfered from 1l2e 1lo7 NO 4 4 D2 D2 11997398 11997398 PID 9837940 On the basis of gel filtration experiments, the thioesterase from Pseudomonas sp. strain CBS was shown to be a homotetramer 1lo8 NO 4 4 D2 D2 11997398 11997398 PID 9837940 On the basis of gel filtration experiments, the thioesterase from Pseudomonas sp. strain CBS was shown to be a homotetramer -- Annotation transfered from 1lo7 1lo9 NO 4 4 D2 D2 11997398 11997398 PID 9837940 On the basis of gel filtration experiments, the thioesterase from Pseudomonas sp. strain CBS was shown to be a homotetramer -- Annotation transfered from 1lo7 1loj_1 NO 7 7 C7 C7 12649441 12649441 Interface conserved with 1n9s (38% id) -- Annotation transfered from 1jbm 1loj_2 NO 7 7 C7 C7 12649441 12649441 Interface conserved with 1n9s (38% id) -- Annotation transfered from 1jbm 1lok NO 1 1 NPS NPS 12176384 12176384 Aminopeptidase from Aeromonas proteolytica (AAP) is a small, monomeric enzyme (32KDa) -- Annotation transfered from 1cp6 1lol NO 2 2 C2 C2 12011084 12011084 SP says dimer - interface geometry conserved with 1q6q (26%) 1lom NO 2 2 C2 C2 12054761 12054761 Domain swapped dimer -- Annotation transfered from 1l5b 1lop PROBNOT 1 1 NPS NPS 8601841 8601841 EcoCyc says monomer 1loq YES 2 2 C2 C2 12011084 12011084 SP says dimer -- Wrong interface -- Annotation transfered from 1kly 1lor NO 2 2 C2 C2 12011084 12011084 SP says dimer - interface geometry conserved with 1q6q (26%) 1los_1 NO 2 2 C2 C2 12011084 12011084 SP says dimer - interface geometry conserved with 1q6q (26%) - automatic transfer from 1lor 1los_2 NO 2 2 C2 C2 12011084 12011084 SP says dimer - interface geometry conserved with 1q6q (26%) - automatic transfer from 1lor 1lou NA 1 1 NPS NPS 10350468 10350468 They introduce a mutation that affects the folding pathway. It could be that it affects the quaternary structure as well but more detailed analysis of where was the mutation introduced and a more careful reading of the paper is necessary to reach a conclusion. 1loz NO 1 1 NPS NPS 9039909 9039909 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1lp4 NO 1 1 NPS NPS 15740749 0 Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. -- Annotation transfered from 1jam 1lp6 NO 2 2 C2 C2 12011084 12011084 SP says dimer - interface geometry conserved with 1q6q (26%) 1lp8 PROBNOT 1 1 NPS NPS 15553110 15553110 PISA says monomeric, plus most RIPs (ribo inact. prot.) are monomeric (type I) -- Annotation transfered from 1lpd 1lpc PROBNOT 1 1 NPS NPS 15553110 15553110 PISA says monomeric, plus most RIPs (ribo inact. prot.) are monomeric (type I) -- Annotation transfered from 1lpd 1lpd PROBNOT 1 1 NPS NPS 15553110 15553110 PISA says monomeric, plus most RIPs (ribo inact. prot.) are monomeric (type I) 1lpf NO 2 2 C2 C2 8487301 8487301 Paper says dimer 1lpi NO 1 1 NPS NPS 9828016 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lpj NO 1 1 NPS NPS 12177003 12177003 Paper says: Cytoplasmic carriers of the retinol molecule are monomeric proteins of ~15.5 kDa 1lpm NO 1 1 NPS NPS -1 0 interesting: change of oligomeric state is associated with activity - the open form of the lipase is found to be present in solution as a dimer, whereas the closed form appears to be a monomer (pid=11084600). -- Annotation transfered from 1trh 1lpn NO 1 1 NPS NPS 8142346 8142346 interesting: change of oligomeric state is associated with activity - the open form of the lipase is found to be present in solution as a dimer, whereas the closed form appears to be a monomer (pid=11084600). -- Annotation transfered from 1trh 1lpo NO 1 1 NPS NPS 8142346 8142346 interesting: change of oligomeric state is associated with activity - the open form of the lipase is found to be present in solution as a dimer, whereas the closed form appears to be a monomer (pid=11084600). -- Annotation transfered from 1trh 1lpp NO 1 1 NPS NPS 8142346 8142346 interesting: change of oligomeric state is associated with activity - the open form of the lipase is found to be present in solution as a dimer, whereas the closed form appears to be a monomer (pid=11084600). -- Annotation transfered from 1trh 1lps NO 1 1 NPS NPS -1 0 interesting: change of oligomeric state is associated with activity - the open form of the lipase is found to be present in solution as a dimer, whereas the closed form appears to be a monomer (pid=11084600). -- Annotation transfered from 1trh 1lpu NO 1 1 NPS NPS 15740749 0 Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. -- Annotation transfered from 1jam 1lpy NO 1 1 NPS NPS 12646375 12646375 1lq0 NO 1 1 NPS NPS 11960986 11960986 Monomer: paper says: the enzyme occurs in two major forms of 39 and 50 kDa. The subsequent cloning of its cDNA from a macrophage library showed that the 50-kDa form can be converted to the 39-kDa form post-translationally or by RNA processing -- Annotation transfered from 1hki 1lq1_1 PROBNOT 2 2 NS NS 12176382 12176382 Paper says: In the crystal lattice, two molecules form a tandem dimer upon binding to adjacent sites on DNA. 1lq1_2 PROBNOT 2 2 NS NS 12176382 12176382 Paper says: In the crystal lattice, two molecules form a tandem dimer upon binding to adjacent sites on DNA. - automatic transfer from 1lq1_1 1lq9 NO 2 2 C2 C2 12514126 12514126 Interface geometry conserved with 1iuj (25%) 1lqe PROBNOT 1 1 NPS NPS 12061878 12061878 -- Annotation transfered from 1az8 1lqf_1 PROBNOT 1 1 NPS NPS 12119018 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1lqf_2 PROBNOT 1 1 NPS NPS 12119018 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1lqf_3 PROBNOT 1 1 NPS NPS 12119018 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1lqf_4 PROBNOT 1 1 NPS NPS 12119018 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1lqw_1 PROBNOT 1 1 NPS NPS 12126617 15382235 Paper implies monomer - related protein are monomeric and PISA says monomer - automatic transfer from 1q1y 1lqw_2 PROBNOT 1 1 NPS NPS 12126617 15382235 Paper implies monomer - related protein are monomeric and PISA says monomer - automatic transfer from 1q1y 1lqx PROBNOT 1 1 NPS NPS 12136141 12136141 Oligomeric state not mentioned - PISA says monomer 1lqy PROBNOT 1 1 NPS NPS 12126617 12126617 Paper says nothing although gel filtration mentioned. Related proteins are monomeric and PISA says monomer 1lr2 NO 1 1 NPS NPS -1 0 Thaumatin is a stable monomeric protein of 22kDa -- Annotation transfered from 1thu 1lr3 NO 1 1 NPS NPS -1 0 Thaumatin is a stable monomeric protein of 22kDa -- Annotation transfered from 1thu 1lr4 NO 1 1 NPS NPS 15740749 0 Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. -- Annotation transfered from 1jam 1lr6 PROBNOT 1 1 NPS NPS 12136141 12136141 Oligomeric state not mentioned - PISA says monomer -- Annotation transfered from 1lqx 1lri PROBNOT 1 1 NPS NPS 12198300 12198300 Out of the three almost identical proteins, no paper mentions a dimer, PISA says dimer for one only so Ill say monomer for all of them. 1lrj NO 2 2 C2 C2 12019271 12019271 SP says homodimer -- Annotation transfered from 2udp 1lrk NO 2 2 C2 C2 12019271 12019271 SP says homodimer -- Annotation transfered from 2udp 1lrl NO 2 2 C2 C2 12019271 12019271 SP says homodimer -- Annotation transfered from 2udp 1lrm NO 2 2 C2 C2 0 0 Dimer because no tetramerization domain - SP is wrong (says dimer) -- Annotation transfered from 1j8u 1lrn NO 4 4 D2 D2 12441100 12441100 Paper says tetramer -- Annotation transfered from 1fws 1lro NO 4 4 D2 D2 12441100 12441100 Paper says tetramer -- Annotation transfered from 1fws 1lrq NO 4 4 D2 D2 12441100 12441100 Paper says tetramer -- Annotation transfered from 1fws 1lru_1 NO 1 1 NPS NPS 12126617 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1lru_2 NO 1 1 NPS NPS 12126617 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1lru_3 NO 1 1 NPS NPS 12126617 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1lry PROBNOT 1 1 NPS NPS 12126617 12126617 Paper says nothing although gel filtration mentioned. Related proteins are monomeric and PISA says monomer 1ls3 NO 4 4 D2 D2 12438316 12438316 Paper describes a tetramer, SP and PISA agree. -- Annotation transfered from 1rv4 1ls6 PROBNOT 1 1 NPS NPS 12471039 12471039 Paper says nothing, PISA says monomer 1ls9 NO 1 1 NPS NPS 12475218 12475218 Paper says: The molecular mass estimated by SDS-PAGE and gel filtration was 9.9 kDa, indicating that the protein is a monomer in solution, regardless of the oxidation state 1lsa NO 1 1 NPS NPS 15299341 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lsb NO 1 1 NPS NPS 15299341 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lsc NO 1 1 NPS NPS 15299341 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lsd NO 1 1 NPS NPS 15299341 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lse NO 1 1 NPS NPS 15299341 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lsf NO 1 1 NPS NPS 15299341 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lsg NO 1 1 NPS NPS 7527555 7527555 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lsm NO 1 1 NPS NPS 8535241 8535241 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lsn NO 1 1 NPS NPS 8535241 8535241 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lsq_1 PROBNOT 1 1 NPS NPS 8648618 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1lsq_2 PROBNOT 1 1 NPS NPS 8648618 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1lst PROBNOT 1 1 NPS NPS 8496186 8496186 Both papers do not mention a dimer - PISA says monomer -- Annotation transfered from 1lag 1lsy NO 1 1 NPS NPS 7966306 7966306 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lsz NO 1 1 NPS NPS 7966306 7966306 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lt1_1 PROBNOT 2 2 C2 C2 12569505 0 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Four helix bundle -- Check symmetry search - automaticaly inferred from 1ovu 1lt1_2 PROBNOT 2 2 C2 C2 12569505 0 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Four helix bundle -- Check symmetry search - automaticaly inferred from 1ovu 1lt1_3 PROBNOT 2 2 C2 C2 12569505 0 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Four helix bundle -- Check symmetry search - automaticaly inferred from 1ovu 1lt1_4 PROBNOT 2 2 C2 C2 12569505 0 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Four helix bundle -- Check symmetry search - automaticaly inferred from 1ovu 1ltd NO 4 4 C2 C4 8003966 2329585 The structure is a cyclic tetramer but only C2 is detected because two small domain (out of the four) are unfolded and not visible. -- Annotation transfered from 1fcb 1lte NO 2 2 C2 C2 1948067 1948067 -- Annotation transfered from 1ax0 1lto PROBNOT 4 4 D2 D2 12162961 12162961 The paper says that it is a tetramer in solution 1ltu PROBNOT 1 1 NPS NPS 12096915 12096915 SP and PISA say monomer -- Annotation transfered from 1ltv 1ltv PROBNOT 1 1 NPS NPS 12096915 12096915 SP and PISA say monomer 1ltw NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1ltz PROBNOT 1 1 NPS NPS 12096915 12096915 SP and PISA say monomer -- Annotation transfered from 1ltv 1lu1 NO 4 4 D2 D2 10047489 10047489 paper says homotetramer -- Annotation transfered from 1lu2 1lu2 NO 4 4 D2 D2 10047489 10047489 paper says homotetramer 1lu4 PROBNOT 1 1 NPS NPS 14597624 14597624 Paper says nothing, PISA says monomer 1lu9 NO 3 3 C3 C3 12176390 12176390 -- Annotation transfered from 1lua 1lua NO 3 3 C3 C3 12176390 12176390 1luc NO 2 2 C2 C2 8703001 8703001 Paper says: Luciferase, as isolated from Vibrio harveyi, is an alpha beta heterodimer. When allowed to fold in the absence of the alpha subunit, either in vitro or in vivo, the beta subunit of enzyme will form a kinetically stable homodimer that does not unfold even after prolonged incubation in 5 M urea at pH 7.0 and 18 degrees C. -- Annotation transfered from 1bsl 1lue NO 1 1 NPS NPS 12939145 12939145 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1luf PROBNOT 1 1 NPS NPS 12220490 12220490 May dimerize upon ligand binding but not here - interesting 1lug PROBNOT 1 1 NPS NPS 0 0 9000633 says monomeric -- Annotation transfered from 1uga 1luq NO 4 4 D2 D2 0 0 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1luv NO 4 4 D2 D2 12627943 12627943 Paper says tetramer -- Annotation transfered from 1n0j 1luw NO 4 4 D2 D2 12627943 12627943 Paper says tetramer -- Annotation transfered from 1n0j 1lv2 YES 1 2 NPS C2 12220494 12220494 Paper says: The HNF4s are known to be obligate homodimers, with the LBD responsible for partner selectivity. HNF4α and HNF4γ LBD behaved as dimers in size-exclusion chromatography, and HNF4γ crystallized with the dimer axis coincident with a crystallographic 2-fold. -- PISA does not find it though ... 1lv7 NA 1 6 NPS C6 12176385 12176385 The native form is not found in the crystal nor can be reconstructed: the protein assembles into a C2 dimer. 1lv8 YES 6 3 D3 C3 15342253 15342253 Gel-filtration of the enzyme at a concentration of 9.2 mg/ml, corresponding to the concentration used for crystallization, in the presence of 0.2 M CaCl2 leads to a molecular mass of 102 kDa for the enzyme. This is compatible with a trimeric form of the enzyme -- very interesting though since the paper says hexamers exists in orther organisms -- Annotation transfered from 1lvu 1lve NO 2 2 C2 C2 9683271 9683271 Interface conserved down to <30% (1cd8)! 1lvg PROBNOT 1 1 NPS NPS 12036965 12036965 SP says monomer, paper says nothing, PISA says monomer 1lvl NO 2 2 C2 C2 1325638 1325638 Paper says dimer 1lvu YES 6 3 D3 C3 15342253 15342253 Gel-filtration of the enzyme at a concentration of 9.2 mg/ml, corresponding to the concentration used for crystallization, in the presence of 0.2 M CaCl2 leads to a molecular mass of 102 kDa for the enzyme. This is compatible with a trimeric form of the enzyme -- very interesting though since the paper says hexamers exists in orther organisms 1lvw NO 4 4 D2 D2 0 0 Interface geometry conserved with 1mc3 (62%) 1lvy PROBNOT 1 1 NPS NPS 15299973 0 -- Annotation transfered from 1c1m 1lw1 NO 3 3 C3 C3 12761216 12761216 Paper says trimer - interface conserved with 1p8c (37%) -- Annotation transfered from 1knc 1lw3 NO 1 1 NPS NPS 14690594 14690594 Was shown to form dimers but via the coiled coil region (12668758) which is not in the crystal structure 1lw4 NO 4 4 D2 D2 12269813 12269813 -- Annotation transfered from 1m6s 1lw5 NO 4 4 D2 D2 12269813 12269813 -- Annotation transfered from 1m6s 1lw9 NO 1 1 NPS NPS 12646375 12646375 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1lwg NO 1 1 NPS NPS 12646375 12646375 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1lwh PROBNOT 2 2 C2 C2 12139940 12139940 Paper says: Gel-filtration studies suggest that, although GTase is mostly monomeric in solution, a small fraction of molecules (<10%) form higher oligomers. Therefore, a protein–protein interface observed in the GTase crystal appears to be consistent with the ability of GTase to form a dimer, albeit an unstable one, in solution. - monomer dimer equilibrium 1lwi PROBYES 2 1 C2 NPS 8718859 8718859 Said to be monomeric in the paper. Also nice paragraph about the function of the prot 1lwj PROBNOT 2 2 C2 C2 12139940 12139940 Paper says: Gel-filtration studies suggest that, although GTase is mostly monomeric in solution, a small fraction of molecules (<10%) form higher oligomers. Therefore, a protein–protein interface observed in the GTase crystal appears to be consistent with the ability of GTase to form a dimer, albeit an unstable one, in solution. - monomer dimer equilibrium -- Annotation transfered from 1lwh 1lwk NO 1 1 NPS NPS 12646375 12646375 -- Annotation transfered from 1lpy 1lwl PROBNOT 1 1 NPS NPS 12197708 12197708 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1lwn NO 2 2 C2 C2 12686153 12686153 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1lwo NO 2 2 C2 C2 12686153 12686153 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1lws PROBNOT 1 1 NPS NPS 12219083 10601013 BU changed since last release and is now corrected - From the paper it seems to be a monomer. - automaticaly inferred from 1ef0 1lwt PROBNOT 1 1 NPS NPS 12219083 10601013 BU changed since last release and is now corrected - From the paper it seems to be a monomer. - automaticaly inferred from 1ef0 1lwx NO 6 6 D3 D3 9207061 9207061 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1lx6 NO 4 4 D2 D2 12109908 12109908 -- Annotation transfered from 1c14 1lx7 NO 6 6 D3 D3 12499542 12499542 Interface geometry conserved with 1q1g (28%) -- Annotation transfered from 1rxy 1lxa NO 3 3 C3 C3 7481807 7481807 Interface geometry conserved with 1j2z (43%) 1lxc NO 4 4 D2 D2 12109908 12109908 -- Annotation transfered from 1c14 1lxe NO 2 2 C2 C2 12377122 12377122 Swapped dimer 1lxz NO 1 1 NPS NPS 12454465 0 Thaumatin is a stable monomeric protein of 22kDa -- Annotation transfered from 1thu 1ly0 NO 1 1 NPS NPS 12454465 0 Thaumatin is a stable monomeric protein of 22kDa -- Annotation transfered from 1thu 1ly2 PROBNOT 1 1 NPS NPS 12122212 12122212 We also find that the protein is monomeric in our crystals, suggesting that the dimeric structure of CD21 seen in the CD21:C3d complex is not physiologically relevant (1GHQ) - interesting 1ly3 PROBNOT 1 1 NPS NPS 12198294 12198294 PISA also says monomer - Human is monomeric so I guess it should be - Only Thermogota seems to be dimeric -- Annotation transfered from 1cd2 1ly4 PROBNOT 1 1 NPS NPS 12198294 12198294 PISA also says monomer - Human is monomeric so I guess it should be - Only Thermogota seems to be dimeric -- Annotation transfered from 1cd2 1ly8_1 PROBNOT 1 1 NPS NPS 12777761 9038188 Peroxidases seem to be monomeric in general - automatic transfer from 1gza 1ly8_2 PROBNOT 1 1 NPS NPS 12777761 9038188 Peroxidases seem to be monomeric in general - automatic transfer from 1gza 1ly9_1 PROBNOT 1 1 NPS NPS 12777760 9038188 Peroxidases seem to be monomeric in general - automatic transfer from 1gza 1ly9_2 PROBNOT 1 1 NPS NPS 12777760 9038188 Peroxidases seem to be monomeric in general - automatic transfer from 1gza 1lyc_1 PROBNOT 1 1 NPS NPS 12777760 9038188 Peroxidases seem to be monomeric in general - automatic transfer from 1gza 1lyc_2 PROBNOT 1 1 NPS NPS 12777760 9038188 Peroxidases seem to be monomeric in general - automatic transfer from 1gza 1lyd NO 1 1 NPS NPS 3074306 3074306 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1lye NO 1 1 NPS NPS 1567817 1567817 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1lyf NO 1 1 NPS NPS 1567817 1567817 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1lyg NO 1 1 NPS NPS 1567817 1567817 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1lyh NO 1 1 NPS NPS 1567817 1567817 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1lyi NO 1 1 NPS NPS 1567817 1567817 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1lyj NO 1 1 NPS NPS 1567817 1567817 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1lyk_1 PROBNOT 1 1 NPS NPS 12777760 9038188 Peroxidases seem to be monomeric in general - automatic transfer from 1gza 1lyk_2 PROBNOT 1 1 NPS NPS 12777760 9038188 Peroxidases seem to be monomeric in general - automatic transfer from 1gza 1lyn NO 2 2 C2 C2 7657696 7657696 Interface geometry conserved with 3lyn (64%) 1lyo NO 1 1 NPS NPS 9659395 9659395 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lys_1 NO 1 1 NPS NPS 15299435 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1lys_2 NO 1 1 NPS NPS 15299435 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1lyv PROBNOT 1 1 NPS NPS 0 0 -- Annotation transfered from 1yts 1lyx YES 2 2 NS C2 12403619 12403619 1lyy NO 1 1 NPS NPS 9039909 9039909 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1lyz NO 1 1 NPS NPS 4856347 4856347 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lz0 PROBYES 1 2 NPS C2 12198488 12198488 15475562 says: The dimerization observed for the soluble construct of O2 mutant enzyme is also observed in the wild-type GTA and GTB structures. An examination of glycosyltransferases with related folds with known structure shows that this dimerization through the N-terminal residues is not a general feature but is specific to the crystal packing of GTA, GTB, and their mutants. - PISA says dimer too -- Annotation transfered from 1lzj 1lz1 NO 1 1 NPS NPS 7334520 7334520 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1lz2 NO 1 1 NPS NPS 886621 886621 1lz4 NO 1 1 NPS NPS 1525170 1525170 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1lz5 NO 1 1 NPS NPS 8486712 8486712 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1lz6 NO 1 1 NPS NPS 8486712 8486712 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1lz7 PROBYES 1 2 NPS C2 12198488 12198488 15475562 says: The dimerization observed for the soluble construct of O2 mutant enzyme is also observed in the wild-type GTA and GTB structures. An examination of glycosyltransferases with related folds with known structure shows that this dimerization through the N-terminal residues is not a general feature but is specific to the crystal packing of GTA, GTB, and their mutants. - PISA says dimer too -- Annotation transfered from 1lzj 1lz8 NO 1 1 NPS NPS 10339407 10339407 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lz9 NO 1 1 NPS NPS 10339408 10339408 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lza NO 1 1 NPS NPS 7707375 7707375 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lzb NO 1 1 NPS NPS 7707375 7707375 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lzc NO 1 1 NPS NPS 7707375 7707375 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lzd NO 1 1 NPS NPS 7707375 7707375 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lze NO 1 1 NPS NPS 7707375 7707375 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lzg NO 1 1 NPS NPS 7707375 7707375 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lzi PROBYES 1 2 NPS C2 12198488 12198488 15475562 says: The dimerization observed for the soluble construct of O2 mutant enzyme is also observed in the wild-type GTA and GTB structures. An examination of glycosyltransferases with related folds with known structure shows that this dimerization through the N-terminal residues is not a general feature but is specific to the crystal packing of GTA, GTB, and their mutants. - PISA says dimer too -- Annotation transfered from 1lzj 1lzj PROBYES 1 2 NPS C2 12198488 12198488 15475562 says: The dimerization observed for the soluble construct of O2 mutant enzyme is also observed in the wild-type GTA and GTB structures. An examination of glycosyltransferases with related folds with known structure shows that this dimerization through the N-terminal residues is not a general feature but is specific to the crystal packing of GTA, GTB, and their mutants. - PISA says dimer too 1lzk YES 1 2 NPS C2 12421810 12421810 Paper says: Determination of the native molecular weight by high resolution gel filtration chromatography supports this model of a stable dimer with an apparent molecular mass of 73 ± 4 kDa. This mode of dimerization is similar to that seen in other members of the hormone-sensitive lipase subfamily 1lzl YES 1 2 NPS C2 12421810 12421810 Paper says: Determination of the native molecular weight by high resolution gel filtration chromatography supports this model of a stable dimer with an apparent molecular mass of 73 ± 4 kDa. This mode of dimerization is similar to that seen in other members of the hormone-sensitive lipase subfamily -- Annotation transfered from 1lzk 1lzo_1 NO 2 2 C2 C2 12403619 12454456 Interface geometry conserved with 1m6j (43%) - paper says dimer - automatic transfer from 1m7p 1lzo_2 NO 2 2 C2 C2 12403619 12454456 Interface geometry conserved with 1m6j (43%) - paper says dimer - automatic transfer from 1m7p 1lzq NO 2 2 C2 C2 12699382 12699382 -- Annotation transfered from 1ajx 1lzr NO 1 1 NPS NPS 7990138 7990138 Lysozyme C is monomeric 1lzs_1 YES 1 2 NPS NPS 7990138 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 1lzs_2 YES 1 2 NPS NPS 7990138 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 1lzt NO 1 1 NPS NPS 2302326 2302326 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1lzv PROBNOT 1 1 NPS NPS 12171926 0 9000633 says monomeric -- Annotation transfered from 1uga 1lzx NO 2 2 C2 C2 12437343 12437343 Clear dimer -- Annotation transfered from 1m00 1lzy NO 1 1 NPS NPS 15299509 0 -- Annotation transfered from 135l 1lzz NO 2 2 C2 C2 12437343 12437343 Clear dimer -- Annotation transfered from 1m00 1m00 NO 2 2 C2 C2 12437343 12437343 Clear dimer 1m07_1 NO 1 1 NPS NPS 12499382 0 - automatic transfer from 1km8 1m07_2 NO 1 1 NPS NPS 12499382 0 - automatic transfer from 1km8 1m0b NO 2 2 C2 C2 15560786 15560786 -- Annotation transfered from 1ajx 1m0k YES 6 3 C3 C3 12206785 12206785 SP says trimer -- Duplicated chains -- Annotation transfered from 1vjm 1m0l NO 3 3 C3 C3 12206785 12206785 SP says trimer -- Annotation transfered from 2brd 1m0m YES 6 4 C3 C3 12206786 12206786 BU changed since last release and is now incorrect - SP says trimer -- Annotation transfered from 1p8u 1m0n NO 4 4 D2 D2 12369820 12369820 Paper says tetramer -- Annotation transfered from 1dge 1m0o NO 4 4 D2 D2 12369820 12369820 Paper says tetramer -- Annotation transfered from 1dge 1m0p NO 4 4 D2 D2 12369820 12369820 Paper says tetramer -- Annotation transfered from 1dge 1m0q NO 4 4 D2 D2 12369820 12369820 Paper says tetramer -- Annotation transfered from 1dge 1m0s NO 2 2 C2 C2 0 0 Interface geometry conserved with 1uj6 (37%) 1m0u NO 2 2 C2 C2 12547198 12547198 1m14 NA 1 1 NPS NPS 12196540 12196540 The present data do not permit us to conclude that these contacts also arise in a cellular context - paper says that the protein may form dimers or even oligomers but they are not sure about these contacts -- Annotation transfered from 1m17 1m15 NO 1 1 NPS NPS 12454458 12454458 Paper says: Arginine kinase is widespread in invertebrates and may be the primordial enzyme because of its widely available substrate, monomeric structure, and presence in protozoa -- interesting: very good family for QS evolution (close monomer, dimer and octamer) -- Annotation transfered from 1p52 1m16_1 PROBNOT 1 1 NPS NPS 14627732 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1m16_2 PROBNOT 1 1 NPS NPS 14627732 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1m17 NA 1 1 NPS NPS 12196540 12196540 The present data do not permit us to conclude that these contacts also arise in a cellular context - paper says that the protein may form dimers or even oligomers but they are not sure about these contacts 1m1b NO 4 4 D2 D2 12162742 12162742 Paper and SP say tetramer 1m1d_1 PROBNOT 1 1 NPS NPS 12391296 11090279 Paper says: Narrow line widths are consistent with gel filtration, chromatographic, and mass spectrometric results that suggest the bromodomain is monomeric in solution. - automatic transfer from 1q2d 1m1d_2 PROBNOT 1 1 NPS NPS 12391296 11090279 Paper says: Narrow line widths are consistent with gel filtration, chromatographic, and mass spectrometric results that suggest the bromodomain is monomeric in solution. - automatic transfer from 1q2d 1m1m NO 2 2 C2 C2 16040614 0 1m1o NO 4 4 D2 D2 12501183 12501183 Paper says tetramer -- Annotation transfered from 1dm3 1m1p_1 PROBNOT 1 1 NPS NPS 12080059 12080059 Paper implies monomer but says that crystal packing may indicate how the cytochrome collide for electron exchange. -- interesting case of possible very transiant interactions - automatic transfer from 1m1r 1m1p_2 PROBNOT 1 1 NPS NPS 12080059 12080059 Paper implies monomer but says that crystal packing may indicate how the cytochrome collide for electron exchange. -- interesting case of possible very transiant interactions - automatic transfer from 1m1r 1m1p_3 PROBNOT 1 1 NPS NPS 12080059 12080059 Paper implies monomer but says that crystal packing may indicate how the cytochrome collide for electron exchange. -- interesting case of possible very transiant interactions - automatic transfer from 1m1r 1m1p_4 PROBNOT 1 1 NPS NPS 12080059 12080059 Paper implies monomer but says that crystal packing may indicate how the cytochrome collide for electron exchange. -- interesting case of possible very transiant interactions - automatic transfer from 1m1r 1m1p_5 PROBNOT 1 1 NPS NPS 12080059 12080059 Paper implies monomer but says that crystal packing may indicate how the cytochrome collide for electron exchange. -- interesting case of possible very transiant interactions - automatic transfer from 1m1r 1m1p_6 PROBNOT 1 1 NPS NPS 12080059 12080059 Paper implies monomer but says that crystal packing may indicate how the cytochrome collide for electron exchange. -- interesting case of possible very transiant interactions - automatic transfer from 1m1r 1m1q PROBNOT 1 1 NPS NPS 12080059 12080059 Paper implies monomer but says that crystal packing may indicate how the cytochrome collide for electron exchange. -- interesting case of possible very transiant interactions -- Annotation transfered from 1m1r 1m1r PROBNOT 1 1 NPS NPS 12080059 12080059 Paper implies monomer but says that crystal packing may indicate how the cytochrome collide for electron exchange. -- interesting case of possible very transiant interactions 1m1t NO 4 4 D2 D2 12501183 12501183 Paper says tetramer -- Annotation transfered from 1dm3 1m1u PROBNOT 1 1 NPS NPS 11034990 11034990 -- Annotation transfered from 1ido 1m20 PROBNOT 1 1 NPS NPS 12199707 12199707 Oligomeric state not mentioned - PISA says monomer -- Annotation transfered from 1lqx 1m2g NO 1 1 NPS NPS 12091395 12091395 The dimers appear to be nonphysiological, because protein contacts in the asymmetric unit are different in the two crystal forms and they involve nonconserved amino acids and solvent molecules. Dynamic light scattering in solution also shows that SIR2-Af1 exists as a monomer. The apparent monomeric state of SIR2-Af1 differs from that of SIR2, which appears to interact with itself, forming a multimer in vitro. -- Annotation transfered from 1m2j 1m2h NO 1 1 NPS NPS 12091395 12091395 The dimers appear to be nonphysiological, because protein contacts in the asymmetric unit are different in the two crystal forms and they involve nonconserved amino acids and solvent molecules. Dynamic light scattering in solution also shows that SIR2-Af1 exists as a monomer. The apparent monomeric state of SIR2-Af1 differs from that of SIR2, which appears to interact with itself, forming a multimer in vitro. -- Annotation transfered from 1m2j 1m2i PROBNOT 1 1 NPS NPS -1 0 Oligomeric state not mentioned - PISA says monomer -- Annotation transfered from 1lqx 1m2j NO 1 1 NPS NPS 12091395 12091395 The dimers appear to be nonphysiological, because protein contacts in the asymmetric unit are different in the two crystal forms and they involve nonconserved amino acids and solvent molecules. Dynamic light scattering in solution also shows that SIR2-Af1 exists as a monomer. The apparent monomeric state of SIR2-Af1 differs from that of SIR2, which appears to interact with itself, forming a multimer in vitro. 1m2k NO 1 1 NPS NPS 12091395 12091395 The dimers appear to be nonphysiological, because protein contacts in the asymmetric unit are different in the two crystal forms and they involve nonconserved amino acids and solvent molecules. Dynamic light scattering in solution also shows that SIR2-Af1 exists as a monomer. The apparent monomeric state of SIR2-Af1 differs from that of SIR2, which appears to interact with itself, forming a multimer in vitro. -- Annotation transfered from 1m2j 1m2n YES 2 1 C2 NPS 12091395 12091395 The dimers appear to be nonphysiological, because protein contacts in the asymmetric unit are different in the two crystal forms and they involve nonconserved amino acids and solvent molecules. Dynamic light scattering in solution also shows that SIR2-Af1 exists as a monomer. The apparent monomeric state of SIR2-Af1 differs from that of SIR2, which appears to interact with itself, forming a multimer in vitro. -- Annotation transfered from 1ici 1m2o PROBNOT 4 4 C2 C2 12239560 12239560 Paper says dimer of hetero-dimers 1m2p NO 1 1 NPS NPS 12419810 12419810 Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. -- Annotation transfered from 1jam 1m2q NO 1 1 NPS NPS 12419810 12419810 Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. -- Annotation transfered from 1jam 1m2r NO 1 1 NPS NPS 12419810 12419810 Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. -- Annotation transfered from 1jam 1m2v PROBNOT 2 2 C2 C2 12239560 12239560 Paper implies that this is a biological dimer. 1m2z NO 2 2 C2 C2 12151000 12151000 paper says homodimer 1m33 PROBNOT 1 1 NPS NPS 12732651 12732651 SP says monomer - PISA too 1m35_1 NO 4 4 D2 D2 12777807 15388923 Paper says tetramer - automatic transfer from 1n51 1m35_2 NO 4 4 D2 D2 12777807 15388923 Paper says tetramer - automatic transfer from 1n51 1m38 PROBNOT 2 2 C2 C2 -1 0 SP says dimer -- Annotation transfered from 1wgi 1m3d_1 NO 6 6 D3 D3 11970952 11970952 Paper says hexamer -- Collagen is a very interesting case for 2 reasons: (i) it link two types of QS (hexameric and tetrameric) and (ii) to forms different types of hexamers (types being defined as particular copies of duplicated genes). 1m3e_1 PROBYES 2 4 C2 D2 12463743 15388917 BU changed since last release and is now incorrect - Pig heart SCOT can exist as both a dimer and a tetramer (Rochet et al., 2000) - automaticaly inferred from 1ooy 1m3e_2 PROBYES 2 4 C2 D2 12463743 15388917 BU changed since last release and is now incorrect - Pig heart SCOT can exist as both a dimer and a tetramer (Rochet et al., 2000) - automaticaly inferred from 1ooy 1m3k NO 4 4 D2 D2 12501183 12501183 Paper says tetramer -- Annotation transfered from 1dm3 1m3s_1 YES 1 4 NPS D2 15363790 16021622 BU changed since last release and is now incorrect - Interface geometry conserved with 1jeo (39%) - automaticaly inferred from 1viv 1m3s_2 YES 1 4 NPS D2 15363790 16021622 BU changed since last release and is now incorrect - Interface geometry conserved with 1jeo (39%) - automaticaly inferred from 1viv 1m3u NO 10 10 D5 D5 12906829 12906829 Paper says: were judged by analytical ultracentrifugation to be decameric in solution - Interface geometry conserved with 1o66 (52%) 1m3z NO 4 4 D2 D2 12501183 12501183 Paper says tetramer -- Annotation transfered from 1dm3 1m40 PROBNOT 1 1 NPS NPS 11996574 11996574 EcoCyc says monomer -- Annotation transfered from 1jwp 1m41 PROBNOT 4 4 D2 D2 12445781 12445781 Paper says: Here, we describe the crystal structure of E. coli alkanesulfonate monooxygenase SsuD, which in solution is a homotetrameric enzyme with a subunit molecular mass of 41,605 Da. - Interface geometry conserved with 1ezw (21%) 1m47 PROBNOT 1 1 NPS NPS 12582206 0 BU changed since last release and is now corrected - - automaticaly inferred from 3ink 1m48_1 PROBNOT 1 1 NPS NPS 12582206 0 BU changed since last release and is now corrected - - automaticaly inferred from 3ink 1m48_2 PROBNOT 1 1 NPS NPS 12582206 0 BU changed since last release and is now corrected - - automaticaly inferred from 3ink 1m49_1 PROBNOT 1 1 NPS NPS 12582206 0 BU changed since last release and is now corrected - - automaticaly inferred from 3ink 1m49_2 PROBNOT 1 1 NPS NPS 12582206 0 BU changed since last release and is now corrected - - automaticaly inferred from 3ink 1m4a PROBNOT 1 1 NPS NPS 12582206 0 BU changed since last release and is now corrected - - automaticaly inferred from 3ink 1m4b PROBNOT 1 1 NPS NPS 12582206 0 BU changed since last release and is now corrected - - automaticaly inferred from 3ink 1m4c_1 PROBNOT 1 1 NPS NPS 12582206 0 BU changed since last release and is now corrected - - automaticaly inferred from 3ink 1m4c_2 PROBNOT 1 1 NPS NPS 12582206 0 BU changed since last release and is now corrected - - automaticaly inferred from 3ink 1m4k NO 1 1 NPS NPS 12668644 12668644 Paper says monomeric 1m4m YES 1 2 NPS C2 10949038 10949038 Paper shows the dimer 1m4n NO 2 2 C2 C2 12686108 12686108 1m4s NO 4 4 D2 D2 12501183 12501183 Paper says tetramer -- Annotation transfered from 1dm3 1m4t NO 4 4 D2 D2 12501183 12501183 Paper says tetramer -- Annotation transfered from 1dm3 1m4z NA 2 1 C2 NPS 12198162 12198162 OVerlap between the homodimer binding site and that of the heterodimer (1zbx). But no info is given in the paper. 1m53 PROBNOT 1 1 NPS NPS 12819210 12819210 Paper says nothing, PISA says monomer 1m59 PROBNOT 1 1 NPS NPS -1 0 Oligomeric state not mentioned - PISA says monomer -- Annotation transfered from 1lqx 1m5b_1 PROBNOT 2 2 C2 C2 12215417 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1m5b_2 PROBNOT 2 2 C2 C2 12215417 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1m5c NO 2 2 C2 C2 12215417 12215417 Paper says this dimer is real -- Annotation transfered from 1mqi 1m5d NO 2 2 C2 C2 12215417 12215417 Paper says this dimer is real -- Annotation transfered from 1mqi 1m5e_1 PROBNOT 2 2 C2 C2 12215417 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1m5e_2 PROBNOT 2 2 C2 C2 12215417 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1m5f_1 PROBNOT 2 2 C2 C2 12215417 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1m5f_2 PROBNOT 2 2 C2 C2 12215417 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1m5j NO 2 2 C2 C2 12110688 12110688 Domain swapped dimer -- Annotation transfered from 1l5b 1m5m NO 2 2 C2 C2 12110688 12110688 Domain swapped dimer -- Annotation transfered from 1l5b 1m5r_1 PROBNOT 1 1 NPS NPS 12445783 8062817 SP says monomer - automatic transfer from 1bgt 1m5r_2 PROBNOT 1 1 NPS NPS 12445783 8062817 SP says monomer - automatic transfer from 1bgt 1m5t NO 1 1 NPS NPS 12176983 12176983 In the absence of reducing agent, DivK undergoes dimerization - Dimerization in the absence of the reducing agent occurred within hours and at rates that increased with pH, leading to a dimer to monomer ratio of ~1 at pH 8.0. Addition of a reducing agent to this mixture led to 100% monomer, suggesting that dimerization of the protein was mediated by disulfide bridge formation through Cys-99. interesting for example where one form only exists in PDB -- Annotation transfered from 1m5u 1m5u NO 1 1 NPS NPS 12176983 12176983 In the absence of reducing agent, DivK undergoes dimerization - Dimerization in the absence of the reducing agent occurred within hours and at rates that increased with pH, leading to a dimer to monomer ratio of ~1 at pH 8.0. Addition of a reducing agent to this mixture led to 100% monomer, suggesting that dimerization of the protein was mediated by disulfide bridge formation through Cys-99. interesting for example where one form only exists in PDB 1m64_1 PROBNOT 1 1 NPS NPS 12356299 10581550 SP says monomer - automatic transfer from 1qjd 1m64_2 PROBNOT 1 1 NPS NPS 12356299 10581550 SP says monomer - automatic transfer from 1qjd 1m6c_1 NO 1 1 NPS NPS 9843395 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1m6c_2 NO 1 1 NPS NPS 9843395 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1m6d PROBYES 2 1 NS NPS 12225749 12225749 Related proteins are monomeric and paper doesnt mention a biological dimer 1m6h NO 2 2 C2 C2 12196016 12196016 -- Annotation transfered from 1m6w 1m6i PROBNOT 1 1 NPS NPS 12198487 12198487 recombinant AIF behaves as a monomer in solution (as determined by analytical ultracentrifugation in the range of micromolar protein concentration, data not shown) - a contact is certainly true but weak so there is probably a monomer dimer equilibrium 1m6j NO 2 2 C2 C2 12270704 12270704 Interface geometry conserved with 1n55 (52%) - paper says dimer 1m6k YES 2 1 C2 NPS 12493831 12493831 Paper says: the OXA-1 molecule is monomeric rather than dimeric 1m6m_1 NO 1 1 NPS NPS 9843395 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1m6m_2 NO 1 1 NPS NPS 9843395 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1m6n NO 2 2 C2 C2 12242434 12242434 Dimeric, as said in paper. 1m6s NO 4 4 D2 D2 12269813 12269813 1m6t PROBNOT 1 1 NPS NPS 12381319 12381319 SP, EcoCyc, PISA say monomer 1m6v PROBNOT 8 8 D2 D2 12130656 11551199 Carbamoyl phosphate synthetase (CPS) from Escherichia coli is allosterically regulated by the metabolites ornithine, IMP, and UMP. Ornithine and IMP function as activators, whereas UMP is an inhibitor. CPS undergoes changes in the state of oligomerization that are dependent on the protein concentration and the binding of allosteric effectors. Ornithine and IMP promote the formation of an (ab)4 tetramer while UMP favors the formation of an (ab)2 dimer. Propagate to all (CPS) please! -) -- Annotation transfered from 1bxr 1m6w NO 2 2 C2 C2 12196016 12196016 1m6x NO 4 4 C4 C4 12559911 12559911 Paper says that it s a tetramer. 1m73 NO 3 3 C3 C3 12914785 0 Paper says trimer -- Annotation transfered from 1ula 1m74 NO 2 2 C2 C2 12242434 12242434 Dimeric, as said in paper. -- Annotation transfered from 1m6n 1m78_1 PROBNOT 1 1 NPS NPS 9374515 9374515 BU changed since last release and is now corrected - Paper says nothing - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1ai9 1m78_2 PROBNOT 1 1 NPS NPS 9374515 9374515 BU changed since last release and is now corrected - Paper says nothing - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1ai9 1m79_1 PROBNOT 1 1 NPS NPS 9374515 9374515 BU changed since last release and is now corrected - Paper says nothing - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1ai9 1m79_2 PROBNOT 1 1 NPS NPS 9374515 9374515 BU changed since last release and is now corrected - Paper says nothing - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1ai9 1m7a_1 PROBNOT 1 1 NPS NPS 9374515 9374515 BU changed since last release and is now corrected - Paper says nothing - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1ai9 1m7a_2 PROBNOT 1 1 NPS NPS 9374515 9374515 BU changed since last release and is now corrected - Paper says nothing - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1ai9 1m7b PROBNOT 1 1 NPS NPS 12163169 12163169 1m7n_1 PROBNOT 1 1 NPS NPS 12138114 11694888 Fragment - Paper says: The IGF1 receptor is structurally homologous to the insulin receptor. Members of this receptor subfamily are heterotetrameric glycoproteins consisting of two extracellular ligand-binding alpha-subunits and two transmembrane catalytic beta-subunits. No dimer mentioned and PISA says monomer - automatic transfer from 1k3a 1m7n_2 PROBNOT 1 1 NPS NPS 12138114 11694888 Fragment - Paper says: The IGF1 receptor is structurally homologous to the insulin receptor. Members of this receptor subfamily are heterotetrameric glycoproteins consisting of two extracellular ligand-binding alpha-subunits and two transmembrane catalytic beta-subunits. No dimer mentioned and PISA says monomer - automatic transfer from 1k3a 1m7o NO 2 2 C2 C2 12454456 12454456 Interface geometry conserved with 1m6j (43%) - paper says dimer -- Annotation transfered from 1m7p 1m7p NO 2 2 C2 C2 12454456 12454456 Interface geometry conserved with 1m6j (43%) - paper says dimer 1m7q PROBNOT 1 1 NPS NPS 12482439 0 -- Annotation transfered from 1kv1 1m7r PROBYES 2 1 C2 NPS 14690594 14690594 Was shown to form dimers but via the coiled coil region (12668758) which is not in the crystal structure 1m7s NO 4 4 D2 D2 12557185 12557185 Interface geometry conserved with 1mqf (40% id) 1m7v NO 2 2 C2 C2 12220171 12220171 Paper says dimer - similar to mamamlian ones - interesting for conservation as many species available -- Annotation transfered from 1m7z 1m7y NO 2 2 C2 C2 12228256 12228256 -- Annotation transfered from 1m4n 1m7z NO 2 2 C2 C2 12220171 12220171 Paper says dimer - similar to mamamlian ones - interesting for conservation as many species available 1m80_1 NO 1 1 NPS NPS 12493833 12732621 Paper says: Arginine kinase is widespread in invertebrates and may be the primordial enzyme because of its widely available substrate, monomeric structure, and presence in protozoa -- interesting: very good family for QS evolution (close monomer, dimer and octamer) - automatic transfer from 1p52 1m80_2 NO 1 1 NPS NPS 12493833 12732621 Paper says: Arginine kinase is widespread in invertebrates and may be the primordial enzyme because of its widely available substrate, monomeric structure, and presence in protozoa -- interesting: very good family for QS evolution (close monomer, dimer and octamer) - automatic transfer from 1p52 1m85 NO 4 4 D2 D2 7791219 7791219 Interface geometry conserved with 1m7s (40% id) -- Annotation transfered from 1mqf 1m8d_1 PROBYES 2 1 C2 NPS 12437348 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1m8d_2 PROBYES 2 1 C2 NPS 12437348 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1m8e_1 PROBYES 2 1 C2 NPS 12437348 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1m8e_2 PROBYES 2 1 C2 NPS 12437348 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1m8f NO 6 6 D3 D3 12810729 12810729 -- Annotation transfered from 1m8g 1m8g NO 6 6 D3 D3 12810729 12810729 1m8h_1 PROBYES 2 1 C2 NPS 12437348 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1m8h_2 PROBYES 2 1 C2 NPS 12437348 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1m8i_1 PROBYES 2 1 C2 NPS 12437348 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1m8i_2 PROBYES 2 1 C2 NPS 12437348 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1m8j NO 6 6 D3 D3 12810729 12810729 -- Annotation transfered from 1m8g 1m8k PROBYES 6 6 C2 D3 12810729 12810729 BU changed since last release and is now incorrect - 1m8r PROBNOT 1 1 NPS NPS 12504079 12504079 SP says monomer -- Annotation transfered from 1m8s 1m8s PROBNOT 1 1 NPS NPS 12504079 12504079 SP says monomer 1m8u PROBNOT 1 1 NPS NPS 0 3052280 y-Crystallins are exclusively monomeric 1m99 NO 2 2 C2 C2 12596270 12596270 -- Annotation transfered from 1bg5 1m9a NO 2 2 C2 C2 12596270 12596270 -- Annotation transfered from 1bg5 1m9b NO 2 2 C2 C2 12596270 12596270 -- Annotation transfered from 1bg5 1m9h NA 1 1 NPS NPS 14718658 14718658 SwissProt says monomer but PISA says dimer. The contacts established in the dimeric form are also found in 1ef3 which is a bit puzzling. --> investigate more - interesting case. 1m9j NO 2 2 C2 C2 12437348 12437348 Clear dimer -- Annotation transfered from 1m9r 1m9k NO 2 2 C2 C2 12437348 12437348 Clear dimer -- Annotation transfered from 1m9r 1m9m NO 2 2 C2 C2 12437348 12437348 Clear dimer -- Annotation transfered from 1m9r 1m9q NO 2 2 C2 C2 12437348 12437348 Clear dimer -- Annotation transfered from 1m9r 1m9r NO 2 2 C2 C2 12437348 12437348 Clear dimer 1m9t_1 PROBYES 2 1 C2 NPS 12437348 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1m9t_2 PROBYES 2 1 C2 NPS 12437348 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1ma0 NO 2 2 C2 C2 12196016 12196016 -- Annotation transfered from 1m6w 1ma3 PROBNOT 1 1 NPS NPS 12408821 12408821 1ma7 YES 4 8 C4 C4 12779336 12779336 BU changed since last release and is now incorrect - -- Annotation transfered from 1kbu 1map NO 2 2 C2 C2 7903048 7903048 Interface geometry conserved with 2ay6 (38%) -- Annotation transfered from 1ivr 1maq NO 2 2 C2 C2 7903048 7903048 Interface geometry conserved with 2ay6 (38%) -- Annotation transfered from 1ivr 1mar NO 1 1 NPS NPS 8234324 8234324 SwissProt and PISA say monomer -- Annotation transfered from 1ads 1mas NO 4 4 D2 D2 8634238 8634238 Interface geometry conserved with 1ezr (78%) 1mav NO 1 1 NPS NPS 12176983 12176983 In the absence of reducing agent, DivK undergoes dimerization - Dimerization in the absence of the reducing agent occurred within hours and at rates that increased with pH, leading to a dimer to monomer ratio of ~1 at pH 8.0. Addition of a reducing agent to this mixture led to 100% monomer, suggesting that dimerization of the protein was mediated by disulfide bridge formation through Cys-99. interesting for example where one form only exists in PDB -- Annotation transfered from 1m5u 1max PROBNOT 1 1 NPS NPS 8605148 8605148 -- Annotation transfered from 1az8 1may PROBNOT 1 1 NPS NPS 8605148 8605148 -- Annotation transfered from 1az8 1mb0 NO 1 1 NPS NPS 12176983 12176983 In the absence of reducing agent, DivK undergoes dimerization - Dimerization in the absence of the reducing agent occurred within hours and at rates that increased with pH, leading to a dimer to monomer ratio of ~1 at pH 8.0. Addition of a reducing agent to this mixture led to 100% monomer, suggesting that dimerization of the protein was mediated by disulfide bridge formation through Cys-99. interesting for example where one form only exists in PDB -- Annotation transfered from 1m5u 1mb3 NO 1 1 NPS NPS 12176983 12176983 In the absence of reducing agent, DivK undergoes dimerization - Dimerization in the absence of the reducing agent occurred within hours and at rates that increased with pH, leading to a dimer to monomer ratio of ~1 at pH 8.0. Addition of a reducing agent to this mixture led to 100% monomer, suggesting that dimerization of the protein was mediated by disulfide bridge formation through Cys-99. interesting for example where one form only exists in PDB -- Annotation transfered from 1m5u 1mb4 NO 2 2 C2 C2 12493825 12493825 1mb8 PROBNOT 1 1 NPS NPS 12791251 12791251 -- Annotation transfered from 1sh6 1mba NO 1 1 NPS NPS 2926816 2926816 Myoglobin is well known to be monomeric -- Annotation transfered from 2fal 1mbc NO 1 1 NPS NPS 3820301 3820301 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mbd NO 1 1 NPS NPS 7278969 7278969 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mbi NO 1 1 NPS NPS 1994031 1994031 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mbn NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mbo NO 1 1 NPS NPS 7463482 7463482 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mbq PROBNOT 1 1 NPS NPS 12445776 12445776 -- Annotation transfered from 1utm 1mbs NO 1 1 NPS NPS 745243 745243 Myoglobin is well known to be monomeric 1mc2 PROBNOT 1 1 NPS NPS 12871974 12871974 Even though usually forms dimer, this one is engineered to not 1mc3 NO 4 4 D2 D2 12171937 12171937 Interface geometry conserved with 1lvw (62%) 1mc4 YES 1 2 NPS C2 12493825 12493825 1mc5 NO 2 2 C2 C2 12484756 12484756 -- Annotation transfered from 1m6w 1mc8 PROBYES 2 1 C2 NPS 12147694 12147694 Paper implies monomer - PISA agrees - The structural flexibility of these two loop regions of phFEN-1 is also indicated by the superimposition of two independent subunit molecules from the dimer structure. -- interesting example (1mc8 and 1b43) of two proteins that are related, that have a big interface, but where the interface is not related (different geometry) AND ARTEFACTUAL! (of course) 1mcb NO 2 2 C2 C2 8346191 8346191 -- Annotation transfered from 1a8j 1mcc NO 2 2 C2 C2 8346191 8346191 -- Annotation transfered from 1a8j 1mcd NO 2 2 C2 C2 8346191 8346191 -- Annotation transfered from 1a8j 1mce NO 2 2 C2 C2 8346191 8346191 -- Annotation transfered from 1a8j 1mcf NO 2 2 C2 C2 8346191 8346191 -- Annotation transfered from 1a8j 1mch NO 2 2 C2 C2 8346191 8346191 -- Annotation transfered from 1a8j 1mci NO 2 2 C2 C2 8346191 8346191 -- Annotation transfered from 1a8j 1mcj NO 2 2 C2 C2 8346191 8346191 -- Annotation transfered from 1a8j 1mck NO 2 2 C2 C2 8346191 8346191 -- Annotation transfered from 1a8j 1mcl YES 4 2 C2 C2 8346191 8346191 1mcn NO 2 2 C2 C2 8346191 8346191 -- Annotation transfered from 1a8j 1mcq NO 2 2 C2 C2 8346191 8346191 -- Annotation transfered from 1a8j 1mcr NO 2 2 C2 C2 8346191 8346191 -- Annotation transfered from 1a8j 1mcs NO 2 2 C2 C2 8346191 8346191 -- Annotation transfered from 1a8j 1mcy NO 1 1 NPS NPS 7657659 7657659 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mcz_1 NO 4 4 D2 D2 12590569 9665697 Interface geometry conserved with 1ovm (25%) - automatic transfer from 1bfd 1mcz_2 NO 4 4 D2 D2 12590569 9665697 Interface geometry conserved with 1ovm (25%) - automatic transfer from 1bfd 1mcz_3 NO 4 4 D2 D2 12590569 9665697 Interface geometry conserved with 1ovm (25%) - automatic transfer from 1bfd 1mcz_4 NO 4 4 D2 D2 12590569 9665697 Interface geometry conserved with 1ovm (25%) - automatic transfer from 1bfd 1md0 PROBNOT 2 2 C2 C2 12221090 12221090 Furthermore, the similarities between the Domain swapped dimer - normally monomeric, swapped segment can exist in two conformation, turns out that this conformation is compatible with domain swapping. Paper says: intramolecular interactions in Ets-1{Delta}N301 and the intermolecular interactions in crystalline Ets-1{Delta}N300 validate the proposal that the latter represents a three-dimensional domain-swapped dimer with the in trans position of HI-1 recapitulating its in cis position in a monomeric state. -- Annotation transfered from 1gvj 1md3 NO 2 2 C2 C2 12414796 12414796 -- Annotation transfered from 9gss 1md4 NO 2 2 C2 C2 12414796 12414796 -- Annotation transfered from 9gss 1md6 PROBNOT 1 1 NPS NPS 12974628 12974628 Paper says nothing, related proteins are monomeric and PISA says monomeric 1md9 PROBNOT 1 1 NPS NPS 12221282 12221282 Paper says: The 59.9-kDa protein, but nothing explicitly linked to olig. state. - In the paper of a related dimeric protein (1ult) is written: are highly conserved among the LC-FACS family (residues involved in dimerization) but not conserved in the other related enzyme families. Therefore, this type of domain swapped homodimer may be a characteristic feature in LC-FACS but not common in other adenylate forming enzyme families. PISA also says monomer -- Annotation transfered from 1mdb 1mdb PROBNOT 1 1 NPS NPS 12221282 12221282 Paper says: The 59.9-kDa protein, but nothing explicitly linked to olig. state. - In the paper of a related dimeric protein (1ult) is written: are highly conserved among the LC-FACS family (residues involved in dimerization) but not conserved in the other related enzyme families. Therefore, this type of domain swapped homodimer may be a characteristic feature in LC-FACS but not common in other adenylate forming enzyme families. PISA also says monomer 1mdc PROBNOT 1 1 NPS NPS 1447782 1447782 SP says monomer 1mdf PROBNOT 1 1 NPS NPS 12221282 12221282 Paper says: The 59.9-kDa protein, but nothing explicitly linked to olig. state. - In the paper of a related dimeric protein (1ult) is written: are highly conserved among the LC-FACS family (residues involved in dimerization) but not conserved in the other related enzyme families. Therefore, this type of domain swapped homodimer may be a characteristic feature in LC-FACS but not common in other adenylate forming enzyme families. PISA also says monomer -- Annotation transfered from 1mdb 1mdl NO 8 8 D4 D4 7893690 7893690 Interface geometry conserved with 1sjb (24%) -- Annotation transfered from 1mns 1mdn_1 NO 1 1 NPS NPS 9843395 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1mdn_2 NO 1 1 NPS NPS 9843395 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1mdo YES 1 2 NPS C2 12429098 12429098 Paper say dimer -- Annotation transfered from 1mdz 1mdq PROBNOT 1 1 NPS NPS 7853407 7853407 EcoCyc says monomer -- Annotation transfered from 1nl5 1mdr NO 8 8 D4 D4 8292591 8292591 Interface geometry conserved with 1sjb (24%) -- Annotation transfered from 1mns 1mdv_1 PROBNOT 1 1 NPS NPS 9890880 1663945 Paper not available, PISA says monomer and family generally monomeric - automatic transfer from 2cym 1mdv_2 PROBNOT 1 1 NPS NPS 9890880 1663945 Paper not available, PISA says monomer and family generally monomeric - automatic transfer from 2cym 1mdx YES 1 2 NPS C2 12429098 12429098 Paper say dimer -- Annotation transfered from 1mdz 1mdy_1 PROBNOT 2 2 NS C2 8181063 8181063 Leucine zipper - HLH dna binding region -- error in symmetry search? 1mdy_2 PROBNOT 2 2 C2 C2 8181063 8181063 BU changed since last release and is now corrected - Leucine zipper - HLH dna binding region -- error in symmetry search? - automaticaly inferred from 1mdy_1 1mdz YES 1 2 NPS C2 12429098 12429098 Paper say dimer 1me3 NO 1 1 NPS NPS 12467703 12467703 The enzyme is a monomeric glycoprotein -- Annotation transfered from 1me4 1me4 NO 1 1 NPS NPS 12467703 1526455 The enzyme is a monomeric glycoprotein 1me5 NO 3 3 C3 C3 12761216 12761216 Paper says trimer - interface conserved with 1p8c (37%) -- Annotation transfered from 1knc 1meg PROBNOT 1 1 NPS NPS 8769310 8769310 SP says monomer and family monomeric 1mej_1 NO 1 1 NPS NPS 12450384 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1mej_2 NO 1 1 NPS NPS 12450384 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1mej_3 NO 1 1 NPS NPS 12450384 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1mem NO 1 1 NPS NPS 9033587 9033587 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa -- Annotation transfered from 1atk 1men_1 NO 1 1 NPS NPS 12450384 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1men_2 NO 1 1 NPS NPS 12450384 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1men_3 NO 1 1 NPS NPS 12450384 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1meo NO 1 1 NPS NPS 12450384 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein 1mep NO 4 4 D2 D2 16452627 16452627 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1mer NO 2 2 C2 C2 9048541 9048541 -- Annotation transfered from 1ajx 1mes NO 2 2 C2 C2 9048541 9048541 -- Annotation transfered from 1ajx 1met NO 2 2 C2 C2 9048541 9048541 -- Annotation transfered from 1ajx 1meu NO 2 2 C2 C2 9048541 9048541 -- Annotation transfered from 1ajx 1mf4 PROBNOT 1 1 NPS NPS 14529280 14529280 Paper says nothing about oligomer - PISA says monomer -- Annotation transfered from 1td7 1mf7 PROBNOT 1 1 NPS NPS 12611591 12611591 -- Annotation transfered from 1ido 1mfa PROBYES 2 1 C2 NPS 7517550 7517550 1mfm NO 1 1 NPS NPS 10329151 10329151 SOD is normally a dimer but this is a monomeric mutant that displays 20% of the activity -- very interesting to study the reasons of dimerization 1mfp NO 4 4 D2 D2 12699381 12699381 -- Annotation transfered from 1c14 1mfr NO 24 24 Octa Octa 10439069 10439069 Interface geometry conserved with 1lb3 (56%) 1mft PROBNOT 2 2 C2 C2 15713492 15713492 Four helix bundle 1mg0_1 PROBNOT 2 2 C2 C2 12501206 9132002 BU changed since last release and is now corrected - - automaticaly inferred from 1lde 1mg0_2 PROBNOT 2 2 C2 C2 12501206 9132002 BU changed since last release and is now corrected - - automaticaly inferred from 1lde 1mg5 PROBNOT 2 2 C2 C2 15581900 15581900 Paper says dimer 1mg6 PROBNOT 1 1 NPS NPS 0 0 Even though usually forms dimer, this one is engineered to not -- Annotation transfered from 1mc2 1mgn NO 1 1 NPS NPS 8307983 8307983 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mgo NO 2 2 C2 C2 12501206 12501206 -- Annotation transfered from 8adh 1mgq NO 7 7 C7 C7 0 12649441 Interface conserved with 1n9s (38% id) -- Annotation transfered from 1jbm 1mgr NA 1 1 NPS NPS 12228255 12228255 Paper says nothing, PISA says dimer and it is actually domain swapped. Email required. 1mgv NO 2 2 C2 C2 12379100 12379100 Paper says dimer -- Annotation transfered from 1mly 1mgw NA 1 1 NPS NPS 12228255 12228255 Paper says nothing, PISA says dimer and it is actually domain swapped. Email required. -- Annotation transfered from 1mgr 1mgy PROBNOT 1 1 NPS NPS 12829500 12829500 PISA does not find the trimer so the trimeric contacts probably do not exist. -- Annotation transfered from 1brd 1mh0_1 PROBNOT 1 1 NPS NPS 12205081 11053836 - automatic transfer from 1doj 1mh0_2 PROBNOT 1 1 NPS NPS 12205081 11053836 - automatic transfer from 1doj 1mh1 PROBNOT 1 1 NPS NPS 9033596 9033596 Small G protein - Interacts with many proteins (SP) and may interact with itself as well --> monomer oligomer equilibrium (11134022) 1mh7 PROBNOT 1 1 NPS NPS 0 0 In a recent paper (PMID 16287060) it forms a dimer of paralogous subunits - gene dup - interesting -- Annotation transfered from 1mh8 1mh8 PROBNOT 1 1 NPS NPS 0 0 In a recent paper (PMID 16287060) it forms a dimer of paralogous subunits - gene dup - interesting 1mh9 NO 2 2 C2 C2 12352955 12352955 The crystal structure of dNT-2 reveals a possible dimeric structure, consistent with gel filtration data. 1mho NO 2 2 C2 C2 8805590 8805590 Paper says dimer 1mhx PROBNOT 1 1 NPS NPS 12441390 12441390 Because it is used in computational design, it is a monomer without a doubt 1mi1 YES 2 1 NS NPS 12234919 12234919 Paper says: Light scattering studies showed that the protein exists as monomers in solution (data not shown). 1mi3_1 NO 2 2 C2 C2 12733986 12102621 Forms a dimer, paper interesting regarding the evolution of oligomeric state - good candidate - automatic transfer from 1jez 1mi3_2 NO 2 2 C2 C2 12733986 12102621 Forms a dimer, paper interesting regarding the evolution of oligomeric state - good candidate - automatic transfer from 1jez 1mi4 PROBNOT 1 1 NPS NPS 12430021 12430021 SP says monomer -- Annotation transfered from 1q36 1mi7 YES 1 2 NPS C2 15274929 15274929 Paper says dimer 1mid PROBNOT 1 1 NPS NPS 0 0 PISA say monomer, consistent with family 1mih_1 PROBNOT 1 1 NPS NPS 12591865 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 1mih_2 PROBNOT 1 1 NPS NPS 12591865 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 1mik PROBNOT 1 1 NPS NPS 7650689 7650689 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 1mil PROBNOT 1 1 NPS NPS 7473762 7473762 1mir YES 2 1 C2 NPS 8740363 8740363 BU changed since last release and is now incorrect - SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) 1mj3 NO 6 6 D3 D3 12445775 12445775 Everyone says hexamer! -- Annotation transfered from 2dub 1mj5 NO 1 1 NPS NPS 14744129 14744129 SP says monomer -- Annotation transfered from 1g42 1mjc PROBNOT 1 1 NPS NPS 8197194 8197194 the dimerization observed in both crystal forms of CspB is impossible for CspA. This is mainly due to the N-terminal extension in CspA - also compatible with the fact that CspB was found mainly as a monomer in solution. 1mjf PROBNOT 2 2 C2 C2 0 0 No paper - PISA says dimer 1mjn PROBNOT 1 1 NPS NPS 12526797 12526797 -- Annotation transfered from 1zon 1mjs NO 1 1 NPS NPS 12154125 12154125 Paper says trimerization is regulated -- very very nice example to show the importance of QS and the functional possibilities it offers 1mjt NO 2 2 C2 C2 12467576 12467576 Paper says dimer 1mjw NO 6 6 D3 D3 9668207 9668207 SP and EcoCyc say hexamer -- Annotation transfered from 1mjz 1mjx NO 6 6 D3 D3 9668207 0 SP and EcoCyc say hexamer -- Annotation transfered from 1mjz 1mjy NO 6 6 D3 D3 9668207 9668207 SP and EcoCyc say hexamer -- Annotation transfered from 1mjz 1mjz NO 6 6 D3 D3 9668207 9668207 SP and EcoCyc say hexamer 1mk1 NO 2 2 C2 C2 12906832 12906832 Domain swapped dimer -- Annotation transfered from 1mqe 1mk4 PROBNOT 2 2 C2 C2 0 0 Similar domain geometry to 1s60 (25% id) 1mk5 NO 4 4 D2 D2 16452627 16452627 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1mk8 PROBNOT 1 1 NPS NPS 12684005 12684005 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1mka NO 2 2 C2 C2 8805534 8805534 Paper says: Dehydrase is a symmetric dimer with an unusual alpha+beta hot dog fold. 15371447 says: Unlike the structure of EcFabA (this one) and other hot dog-fold proteins, the PaFabZ monomer forms a higher order hexameric structure. - this one seems to be a dimer. -- Annotation transfered from 1mkb 1mkb NO 2 2 C2 C2 8805534 8805534 Paper says: Dehydrase is a symmetric dimer with an unusual alpha+beta hot dog fold. 15371447 says: Unlike the structure of EcFabA (this one) and other hot dog-fold proteins, the PaFabZ monomer forms a higher order hexameric structure. - this one seems to be a dimer. 1mkd_1 PROBYES 6 4 D3 D2 12387865 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1mkd_2 PROBYES 6 4 D3 D2 12387865 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1mkh NO 2 2 C2 C2 12390027 12390027 Paper says dimer 1mkj NO 1 1 NPS NPS 12368902 12368902 Missing dimerization coil-coil 1mkq PROBNOT 1 1 NPS NPS 12684005 12684005 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1mkr PROBNOT 1 1 NPS NPS 12684005 12684005 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1mks PROBNOT 1 1 NPS NPS 9115986 9115986 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1o2e 1mkt PROBYES 2 1 C2 NPS 9761901 9761901 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1bpq 1mku PROBNOT 1 1 NPS NPS 9115986 9115986 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1o2e 1mkv PROBYES 2 1 C2 NPS 9761900 9761900 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1bpq 1mkz YES 2 6 C2 D3 15269205 15269205 Paper says hexamer 1ml1_1 PROBYES 2 1 NS NPS 9089815 16100954 BU changed since last release and is now incorrect - Paper says this is an engineered monomeric TIM - automaticaly inferred from 1tri 1ml1_2 PROBYES 2 1 C2 NPS 9089815 16100954 BU changed since last release and is now incorrect - Paper says this is an engineered monomeric TIM - automaticaly inferred from 1tri 1ml1_3 PROBYES 2 1 NS NPS 9089815 16100954 BU changed since last release and is now incorrect - Paper says this is an engineered monomeric TIM - automaticaly inferred from 1tri 1ml2 PROBNOT 1 1 NPS NPS 12684005 12684005 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1ml3 NO 4 4 D2 D2 12795610 12795610 SP says tetramer - papers too -- Annotation transfered from 1k3t 1ml4 YES 3 3 C3 C3 12547202 12547202 -- wrong reconstruction 1ml6 NO 2 2 C2 C2 12549910 12549910 glutathione S-transferases are functional dimers. -- Annotation transfered from 1f3a 1mlf NO 1 1 NPS NPS 7837273 7837273 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mlg NO 1 1 NPS NPS 7837273 7837273 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mlh NO 1 1 NPS NPS 7837273 7837273 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mlj NO 1 1 NPS NPS 7837273 7837273 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mlk NO 1 1 NPS NPS 7837273 7837273 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mll NO 1 1 NPS NPS 7837273 7837273 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mlm NO 1 1 NPS NPS 7837273 7837273 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mln NO 1 1 NPS NPS 7837273 7837273 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mlo NO 1 1 NPS NPS 7837273 7837273 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mlq NO 1 1 NPS NPS 7837273 7837273 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mlr NO 1 1 NPS NPS 7837273 7837273 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mls NO 1 1 NPS NPS 7837273 7837273 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mlu NO 1 1 NPS NPS 8075059 8075059 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mlw NO 1 1 NPS NPS 12379098 12379098 1mly NO 2 2 C2 C2 12218056 12218056 Paper says dimer 1mlz NO 2 2 C2 C2 12218056 12218056 Paper says dimer -- Annotation transfered from 1mly 1mm6 NO 2 2 C2 C2 12501192 12501192 Paper says this dimer is real -- Annotation transfered from 1mqi 1mm7_1 PROBNOT 2 2 C2 C2 12501192 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mm7_2 PROBNOT 2 2 C2 C2 12501192 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mm9 YES 4 4 C2 D2 12777798 12777798 -- Annotation transfered from 1vwl 1mmb PROBNOT 1 1 NPS NPS 7577999 7577999 No clear evidence after a quick search but PISA agrees ... -- Annotation transfered from 1a85 1mmj PROBNOT 1 1 NPS NPS 12467609 12467609 -- Annotation transfered from 1c1m 1mmk NO 2 2 C2 C2 14568534 14568534 Dimer because no tetramerization domain - SP is wrong (says dimer) -- Annotation transfered from 1j8u 1mml PROBYES 2 1 C2 NPS 8535782 8535782 -- Annotation transfered from 1d0e 1mmm NO 2 2 C2 C2 -1 0 PAper, SP say dimer -- Annotation transfered from 1i0h 1mmt NO 2 2 C2 C2 14568534 14568534 Dimer because no tetramerization domain - SP is wrong (says dimer) -- Annotation transfered from 1j8u 1mmv NO 2 2 C2 C2 12960153 12960153 Clear dimer -- Annotation transfered from 1m00 1mmw NO 2 2 C2 C2 12960153 12960153 Clear dimer -- Annotation transfered from 1m00 1mn7 NO 6 6 D3 D3 12171931 12171931 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1mn9 NO 6 6 D3 D3 12606760 12606760 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1mnc PROBNOT 1 1 NPS NPS 7656015 7656015 No clear evidence after a quick search but PISA agrees ... -- Annotation transfered from 1a85 1mnf NO 14 14 D7 D7 14623189 14623189 -- Annotation transfered from 1kp8 1mng NO 4 4 D2 D2 7849024 7849024 Paper says tetramer - the tetramer has essentially the same geometry as the human SOD (1em1). However the nature of the interfaces has changed -- very interesting example of interface evolution! -- Annotation transfered from 3mds 1mnh NO 1 1 NPS NPS 7612611 7612611 Myoglobin is well known to be monomeric 1mni_1 NO 1 1 NPS NPS 7608158 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1mni_2 NO 1 1 NPS NPS 7608158 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1mnj_1 NO 1 1 NPS NPS 7612611 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1mnj_2 NO 1 1 NPS NPS 7612611 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1mnk_1 NO 1 1 NPS NPS 7612611 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1mnk_2 NO 1 1 NPS NPS 7612611 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1mno_1 NO 1 1 NPS NPS 9843395 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1mno_2 NO 1 1 NPS NPS 9843395 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1mns NO 8 8 D4 D4 8292591 8292591 Interface geometry conserved with 1sjb (24%) 1mnz NO 4 4 D2 D2 0 0 -- Annotation transfered from 4xis 1mo0 NO 2 2 C2 C2 12696058 12696058 Interface geometry conserved with 1m6j (49%) 1mo1_1 NO 2 2 C2 C2 0 12972249 Reversible domain swapping - Whereas HPr is monomeric in solution, Crh forms a mixture of monomers and dimers in a slowly exchanging equilibrium that takes place within a matter of hours. - automatic transfer from 1mu4 1mo1_2 NO 2 2 C2 C2 0 12972249 Reversible domain swapping - Whereas HPr is monomeric in solution, Crh forms a mixture of monomers and dimers in a slowly exchanging equilibrium that takes place within a matter of hours. - automatic transfer from 1mu4 1mo9 NO 2 2 C2 C2 12390015 12390015 Paper says dimer 1moa NO 1 1 NPS NPS 1629229 1629229 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mob NO 1 1 NPS NPS 8230194 8230194 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1moc NO 1 1 NPS NPS 8230194 8230194 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mod NO 1 1 NPS NPS 8230194 8230194 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1moe PROBNOT 2 2 C2 C2 12559905 12559905 1moj NO 12 12 Tetr Tetr 15365182 15365182 Interface geometry conserved with 1o9r (25%) 1mok_1 NO 2 2 C2 C2 12390015 12390015 Paper says dimer - automatic transfer from 1mo9 1mok_2 NO 2 2 C2 C2 12390015 12390015 Paper says dimer - automatic transfer from 1mo9 1mom PROBNOT 1 1 NPS NPS 8143869 8143869 No info in papers, PISA says monomer -- Annotation transfered from 1aha 1moo PROBNOT 1 1 NPS NPS 12499545 12499545 9000633 says monomeric -- Annotation transfered from 1uga 1mou YES 4 1 C2 NPS 12623015 12623015 A mutation has been introduced to convert the tetrameric form into a monomeric one - interesting 1mov NO 4 4 D2 D2 12623015 12623015 Paper says tetrameric 1moy YES 4 4 C2 D2 12777798 12777798 -- Annotation transfered from 1vwl 1moz_1 PROBNOT 1 1 NPS NPS 11535602 11535602 May form homodimers, but this one has been mutated (C --> S) which prevents homodimer formation -- Annotation transfered from 1moz_2 1moz_2 PROBNOT 1 1 NPS NPS 11535602 11535602 May form homodimers, but this one has been mutated (C --> S) which prevents homodimer formation 1mp0 NO 2 2 C2 C2 12604204 12604204 -- Annotation transfered from 1m6w 1mp2 NO 2 2 C2 C2 12906832 12906832 Domain swapped dimer -- Annotation transfered from 1mqe 1mp3 NO 4 4 D2 D2 12374866 12374866 Interface geometry conserved with 1lvw (61%) -- Annotation transfered from 1iim 1mp4 NA 4 2 NS C2 12374866 12374866 Non native structure: should be a tetramer 1mp5 NO 4 4 D2 D2 12374866 12374866 Interface geometry conserved with 1lvw (61%) -- Annotation transfered from 1iim 1mp8 PROBNOT 1 1 NPS NPS 12467573 12467573 Paper says nothing about a oligomer, PISA says monomer 1mp9 NO 2 2 C2 C2 14725775 14725775 Interface geometry conserved with 1tbp (46%) 1mpb PROBNOT 1 1 NPS NPS 8951382 8951382 EcoCyc says monomer -- Annotation transfered from 1nl5 1mpc PROBNOT 1 1 NPS NPS 8951382 8951382 EcoCyc says monomer -- Annotation transfered from 1nl5 1mpd PROBNOT 1 1 NPS NPS 8951382 8951382 EcoCyc says monomer -- Annotation transfered from 1nl5 1mpf NO 3 3 C3 C3 7524100 7524100 Interface geometry conserved with 1prn (20%) -- Annotation transfered from 1gfn 1mpl PROBNOT 1 1 NPS NPS 12564922 12564922 the Streptomyces R61 and Actinomadura R39 DD-peptidases, are water-soluble monomeric proteins; (12723972) -- Annotation transfered from 1pwd 1mpt NO 1 1 NPS NPS 15299321 0 -- Annotation transfered from 1c9n 1mpu NO 2 2 C2 C2 12679019 12679019 Paper says dimer -- interessting: symmetric molecule and asymmetric binding partner. (11224525) 1mpw_1 PROBNOT 1 1 NPS NPS 12526670 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1mpw_2 PROBNOT 1 1 NPS NPS 12526670 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1mpy NO 4 4 D2 D2 10368270 10368270 Paper says tetramer - interface geometry conserved with 1f1x -- interesting example: dimeric unit same in D2 and in D4 1mq4 PROBNOT 1 1 NPS NPS 12467573 12467573 Paper does not mention oligomer - PISA says monomer 1mq5 PROBNOT 2 2 NPS NPS 12501180 12501180 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1mq6 PROBNOT 2 2 NPS NPS 12501180 12501180 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1mq7 NO 3 3 C3 C3 15276840 15276840 Paper says: dUTPases are primarily homotrimeric and catalyze the metal ion dependent hydrolysis of dUTP to 2′-deoxyuridine 5′-monophosphate (dUMP) and pyrophosphate. -- Annotation transfered from 1snf 1mq9 PROBNOT 1 1 NPS NPS 12526797 12526797 -- Annotation transfered from 1zon 1mqa PROBNOT 1 1 NPS NPS 12526797 12526797 -- Annotation transfered from 1zon 1mqd_1 PROBNOT 2 2 C2 C2 12417307 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mqd_2 PROBNOT 2 2 C2 C2 12417307 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mqd_3 PROBNOT 2 2 C2 C2 12417307 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mqd_4 PROBNOT 2 2 C2 C2 12417307 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mqe NO 2 2 C2 C2 12906832 12906832 Domain swapped dimer 1mqf NO 4 4 D2 D2 14646074 14646074 Interface geometry conserved with 1m7s (40% id) 1mqg_1 PROBNOT 2 2 C2 C2 12872125 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mqg_2 YES 2 2 NS C2 12872125 12015593 BU changed since last release and is now incorrect - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mqh NO 2 2 C2 C2 12872125 12872125 Paper says this dimer is real -- Annotation transfered from 1mqi 1mqi NO 2 2 C2 C2 12872125 12872125 Paper says this dimer is real 1mqj NO 2 2 C2 C2 12872125 12872125 Paper says this dimer is real -- Annotation transfered from 1mqi 1mqo NO 1 1 NPS NPS 0 0 -- Annotation transfered from 1bvt 1mqp NO 2 2 C2 C2 14573597 14573597 Homodimer -- Annotation transfered from 1mqq 1mqq NO 2 2 C2 C2 14573597 15466046 Homodimer 1mqr NO 2 2 C2 C2 14573597 14573597 Homodimer -- Annotation transfered from 1mqq 1mqw NO 2 2 C2 C2 12906832 12906832 Domain swapped dimer -- Annotation transfered from 1mqe 1mr2 NO 2 2 C2 C2 12906832 12906832 Domain swapped dimer -- Annotation transfered from 1mqe 1mr3 PROBNOT 1 1 NPS NPS 11535602 11535602 Normally form a dimer via a disulphide bridge. However, the cysteine has been mutated in this structure. No phenotype was observed. This is described in detail in the paper. 1mr7_1 NO 3 3 C3 C3 12771141 11841212 Interface geometry conserved with 1xat (42%) - automatic transfer from 1kk6 1mr7_2 NO 3 3 C3 C3 12771141 11841212 Interface geometry conserved with 1xat (42%) - automatic transfer from 1kk6 1mr8 NO 2 2 C2 C2 10771424 10771424 Paper says dimer 1mra NO 8 8 D4 D4 8639525 8639525 Interface geometry conserved with 1sjb (24%) -- Annotation transfered from 1mns 1mrg PROBNOT 1 1 NPS NPS 7619070 7619070 No info in papers, PISA says monomer -- Annotation transfered from 1aha 1mrh PROBNOT 1 1 NPS NPS 7619070 7619070 No info in papers, PISA says monomer -- Annotation transfered from 1aha 1mri PROBNOT 1 1 NPS NPS 7619070 7619070 No info in papers, PISA says monomer -- Annotation transfered from 1aha 1mrj PROBNOT 1 1 NPS NPS 7619070 7619070 No info, PISA says monomer -- Annotation transfered from 1mrk 1mrk PROBNOT 1 1 NPS NPS 7619070 7619070 No info, PISA says monomer 1mrl NO 3 3 C3 C3 12771141 12771141 Interface geometry conserved with 1xat (42%) -- Annotation transfered from 1kk6 1mrn NO 2 2 C2 C2 12454011 12454011 Homodimer 1mrp PROBYES 2 1 C2 NPS 9360608 9360608 1mrq PROBNOT 1 1 NPS NPS 12899831 12899831 Swissprot and PISA say it is a monomer 1mrs NO 2 2 C2 C2 12454011 12454011 Homodimer -- Annotation transfered from 1mrn 1mru_1 PROBNOT 1 1 NPS NPS 12548283 12551895 A further step of gel filtration in a Superdex 75 column was performed to separate the monomeric protein from aggregated material. - automatic transfer from 1o6y 1mru_2 PROBNOT 1 1 NPS NPS 12548283 12551895 A further step of gel filtration in a Superdex 75 column was performed to separate the monomeric protein from aggregated material. - automatic transfer from 1o6y 1mrv PROBNOT 1 1 NPS NPS 12517337 12517337 Paper says nothing about oligomer - PISA says monomer -- Annotation transfered from 1o6l 1mrw NO 2 2 C2 C2 15103623 15103623 -- Annotation transfered from 1ajx 1mrx NO 2 2 C2 C2 15103623 15103623 -- Annotation transfered from 1ajx 1mry PROBNOT 1 1 NPS NPS 12517337 12517337 Paper says nothing about oligomer - PISA says monomer -- Annotation transfered from 1o6l 1mrz PROBYES 2 1 NS NPS 12910462 12910462 Enzyme, no reason for that type of interaction, plus this is a thermophile. 1ms6 PROBNOT 1 1 NPS NPS 12459015 12459015 SP says monomer -- Annotation transfered from 1nqc 1ms7_1 PROBNOT 2 2 C2 C2 12417307 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1ms7_2 PROBNOT 2 2 C2 C2 12417307 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1msb PROBNOT 2 2 C2 C2 1721241 1721241 Interface geometry conserved with 1rdk (>50%) - although the interface structure has changed. 1msc PROBNOT 2 2 C2 C2 7788292 7788292 Two fold axis of the virus shell 1msd NO 4 4 D2 D2 8495200 8495200 Paper says tetramer -- Annotation transfered from 1n0j 1msm NO 2 2 C2 C2 15103623 15103623 -- Annotation transfered from 1ajx 1msn NO 2 2 C2 C2 15103623 15103623 -- Annotation transfered from 1ajx 1mss NA 2 1 C2 NPS 8591044 0 This protein is normally dimeric but has been engineered to be monomeric. In addition the number of residues at the interface is quite large - interesting 1mt0 PROBNOT 1 1 NPS NPS 12823972 12823972 Paper says: we suggest that this conformation may represent a latent monomeric form of the NBD. - non-native state (normally homodimeric). 1mt3 NO 1 1 NPS NPS 12374735 12374735 F1 exists as a monomer in solution, as has been confirmed by gel filtration and dynamic light scattering experiments. -- Annotation transfered from 1mtz 1mt6 PROBNOT 1 1 NPS NPS 12389038 12389038 Paper says all SET proteins are monomeric -- Annotation transfered from 1muf 1mt7 NO 2 2 C2 C2 12502847 12502847 -- Annotation transfered from 1ajx 1mt8 NO 2 2 C2 C2 12502847 12502847 -- Annotation transfered from 1ajx 1mt9 NO 2 2 C2 C2 12502847 12502847 -- Annotation transfered from 1ajx 1mtb NO 2 2 C2 C2 12502847 12502847 -- Annotation transfered from 1ajx 1mtc NO 2 2 C2 C2 12484753 12484753 -- Annotation transfered from 6gsv 1mti NO 1 1 NPS NPS 7479707 7479707 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mtj NO 1 1 NPS NPS 7479707 7479707 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mtk NO 1 1 NPS NPS 7479707 7479707 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mto_1 NO 4 4 D2 D2 12390023 2136935 12015149: The eubacterial ATP-dependent PFKs, of which the E. coli enzyme is the best-studied example, are allosterically regulated homotetramers - automatic transfer from 6pfk 1mto_2 NO 4 4 D2 D2 12390023 2136935 12015149: The eubacterial ATP-dependent PFKs, of which the E. coli enzyme is the best-studied example, are allosterically regulated homotetramers - automatic transfer from 6pfk 1mtr NO 2 2 C2 C2 -1 0 -- Annotation transfered from 1ajx 1mts PROBNOT 1 1 NPS NPS 7498454 7498454 -- Annotation transfered from 1az8 1mtu PROBNOT 1 1 NPS NPS 7498454 7498454 -- Annotation transfered from 1az8 1mtv PROBNOT 1 1 NPS NPS 7498454 7498454 -- Annotation transfered from 1az8 1mtw PROBNOT 1 1 NPS NPS 7498454 7498454 -- Annotation transfered from 1az8 1mtz NO 1 1 NPS NPS 12374735 12374735 F1 exists as a monomer in solution, as has been confirmed by gel filtration and dynamic light scattering experiments. 1mu0 NO 1 1 NPS NPS 12374735 12374735 F1 exists as a monomer in solution, as has been confirmed by gel filtration and dynamic light scattering experiments. -- Annotation transfered from 1mtz 1mu4 NO 2 2 C2 C2 12972249 12972249 Reversible domain swapping - Whereas HPr is monomeric in solution, Crh forms a mixture of monomers and dimers in a slowly exchanging equilibrium that takes place within a matter of hours. 1mu7_1 PROBNOT 1 1 NPS NPS 12470949 11839309 Paper says monomer - automatic transfer from 1jy1 1mu7_2 PROBNOT 1 1 NPS NPS 12470949 11839309 Paper says monomer - automatic transfer from 1jy1 1mu9_1 PROBNOT 1 1 NPS NPS 12470949 11839309 Paper says monomer - automatic transfer from 1jy1 1mu9_2 PROBNOT 1 1 NPS NPS 12470949 11839309 Paper says monomer - automatic transfer from 1jy1 1mua PROBNOT 1 1 NPS NPS 8218160 8218160 9000633 says monomeric -- Annotation transfered from 1uga 1muc NO 8 8 D4 D4 7500361 7500361 Paper says octamer -- Annotation transfered from 2muc 1mud PROBNOT 1 1 NPS NPS 9846876 9846876 Ecocyc says monomer -- Annotation transfered from 1kg3 1muf PROBNOT 1 1 NPS NPS 12389038 12372304 Paper says all SET proteins are monomeric 1mui NO 2 2 C2 C2 12057670 12057670 -- Annotation transfered from 1ajx 1mul YES 1 2 NPS C2 12875839 12875839 Domain Swapped dimer 1mum NO 4 4 D2 D2 12706720 0 Interface geometry conserved with 1pym (30%) -- Annotation transfered from 1oqf 1mun PROBYES 2 1 C2 NPS 9846876 9846876 Ecocyc says monomer - paper does not speak about a dimer -- Annotation transfered from 1muy 1muo PROBNOT 1 1 NPS NPS 12237287 12237287 Paper does not mention oligomer - PISA says monomer -- Annotation transfered from 1mq4 1mup PROBNOT 1 1 NPS NPS 1279439 1279439 Gel filtration performed and no dimer or oligomer mentioned. -- Annotation transfered from 1i06 1muq NO 10 10 D5 D5 15049685 15049685 Consistent with the decamer seen in these two crystal forms, RSL was found to have a molecular mass of ~150 kDa as determined by gel filtration in the absence of Ca2+ - disulfide linked dimers 1muw YES 1 4 NPS D2 0 0 1muy PROBYES 2 1 C2 NPS 9846876 9846876 Ecocyc says monomer - paper does not speak about a dimer 1mv5 YES 4 2 C2 C2 0 0 No paper - 10835349 says homodimer - the one here is probably wrong (different from 1l2t, which is supposedly right from the paper). 1mv9 NO 2 2 C2 C2 11981034 11981034 Paper says dimer -- Annotation transfered from 1lbd 1mvc NO 2 2 C2 C2 11981034 11981034 Paper says dimer -- Annotation transfered from 1lbd 1mvl YES 3 3 NS C3 12614618 12614618 10986463 says: Gel-filtration chromatography experiments show that AtHal3 is also a trimer in solution 1mvn NO 3 3 C3 C3 12614618 12614618 Paper says: Gel-filtration chromatography experiments show that AtHal3 is also a trimer in solution -- Annotation transfered from 1e20 1mvo PROBNOT 2 2 NS NS 12486062 12486062 Paper says biological asymetric dimer 1mvq NO 4 4 D2 D2 12966038 12966038 1mvs PROBNOT 1 1 NPS NPS 12657784 12657784 -- Annotation transfered from 1s3u 1mvt PROBNOT 1 1 NPS NPS 12657784 12657784 -- Annotation transfered from 1s3u 1mvy NO 1 1 NPS NPS 12364331 12364331 9882648 says: Under both native and denaturing conditions, the molecular mass obtained was 70 ± 2 kDa (Fig. 3B). This result demonstrates the monomeric structure of the amylosucrase from N. polysaccharea -- Annotation transfered from 1mw1 1mw0 NO 1 1 NPS NPS 12364331 12364331 9882648 says: Under both native and denaturing conditions, the molecular mass obtained was 70 ± 2 kDa (Fig. 3B). This result demonstrates the monomeric structure of the amylosucrase from N. polysaccharea -- Annotation transfered from 1mw1 1mw1 NO 1 1 NPS NPS 12364331 12364331 9882648 says: Under both native and denaturing conditions, the molecular mass obtained was 70 ± 2 kDa (Fig. 3B). This result demonstrates the monomeric structure of the amylosucrase from N. polysaccharea 1mw2 NO 1 1 NPS NPS 12364331 12364331 9882648 says: Under both native and denaturing conditions, the molecular mass obtained was 70 ± 2 kDa (Fig. 3B). This result demonstrates the monomeric structure of the amylosucrase from N. polysaccharea -- Annotation transfered from 1mw1 1mw3 NO 1 1 NPS NPS 12364331 12364331 9882648 says: Under both native and denaturing conditions, the molecular mass obtained was 70 ± 2 kDa (Fig. 3B). This result demonstrates the monomeric structure of the amylosucrase from N. polysaccharea -- Annotation transfered from 1mw1 1mw8 PROBNOT 1 1 NPS NPS 14604525 14604525 SP says monomer 1mw9 PROBNOT 1 1 NPS NPS 14604525 14604525 SP says monomer -- Annotation transfered from 1mw8 1mwc_1 NO 1 1 NPS NPS 9843395 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1mwc_2 NO 1 1 NPS NPS 9843395 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1mwd_1 NO 1 1 NPS NPS 9843395 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1mwd_2 NO 1 1 NPS NPS 9843395 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1mwo PROBNOT 1 1 NPS NPS 12482867 12482867 Paper says nothing, related proteins are monomers and PISA says monomer -- Annotation transfered from 1mxg 1mww NO 3 3 C3 C3 0 0 interface conserved with 1otf (21%) 1mx1 NO 6 6 D3 D3 12725862 12725862 exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. 1mx2_1 PROBNOT 1 1 NPS NPS 12370184 9437433 BU changed since last release and is now corrected - - automaticaly inferred from 1ihb 1mx2_2 PROBNOT 1 1 NPS NPS 12370184 9437433 BU changed since last release and is now corrected - - automaticaly inferred from 1ihb 1mx3 YES 1 1 NPS NPS 12419229 12419229 Interface conserved with 2nac (31%) -- Annotation transfered from 1hku 1mx4_1 PROBNOT 1 1 NPS NPS 12370184 9437433 BU changed since last release and is now corrected - - automaticaly inferred from 1ihb 1mx4_2 PROBNOT 1 1 NPS NPS 12370184 9437433 BU changed since last release and is now corrected - - automaticaly inferred from 1ihb 1mx5_1 PROBYES 3 6 C3 D3 12679808 12725862 BU changed since last release and is now incorrect - exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automaticaly inferred from 1mx1 1mx5_2 PROBYES 3 6 C3 D3 12679808 12725862 BU changed since last release and is now incorrect - exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automaticaly inferred from 1mx1 1mx6_1 PROBNOT 1 1 NPS NPS 12370184 9437433 BU changed since last release and is now corrected - - automaticaly inferred from 1ihb 1mx6_2 PROBNOT 1 1 NPS NPS 12370184 9437433 BU changed since last release and is now corrected - - automaticaly inferred from 1ihb 1mx9_1 NO 6 6 D3 D3 12679808 12725862 exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automatic transfer from 1mx1 1mx9_2 NO 6 6 D3 D3 12679808 12725862 exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automatic transfer from 1mx1 1mxa PROBYES 2 4 C2 D2 8611562 8611562 Paper says tetramer -- Annotation transfered from 1xrc 1mxb PROBYES 2 4 C2 D2 8611562 8611562 Paper says tetramer -- Annotation transfered from 1xrc 1mxc PROBYES 2 4 C2 D2 8611562 8611562 Paper says tetramer -- Annotation transfered from 1xrc 1mxd PROBNOT 1 1 NPS NPS 12482867 12482867 Paper says nothing, related proteins are monomers and PISA says monomer -- Annotation transfered from 1mxg 1mxf NO 4 4 D2 D2 16168672 16168672 the enzyme, like PTR1, exists as a tetramer in solution -- Annotation transfered from 1mxh 1mxg PROBNOT 1 1 NPS NPS 12482867 12482867 Paper says nothing, related proteins are monomers and PISA says monomer 1mxh NO 4 4 D2 D2 16168672 16168672 the enzyme, like PTR1, exists as a tetramer in solution 1mxo_1 PROBNOT 1 1 NPS NPS 12526668 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1mxo_2 PROBNOT 1 1 NPS NPS 12526668 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1mxu_1 PROBNOT 2 2 C2 C2 12731861 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mxu_2 PROBNOT 2 2 C2 C2 12731861 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mxv_1 PROBNOT 2 2 C2 C2 12731861 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mxv_2 PROBNOT 2 2 C2 C2 12731861 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mxw_1 PROBNOT 2 2 C2 C2 12872125 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mxw_2 PROBNOT 2 2 C2 C2 12872125 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mxx_1 PROBNOT 2 2 C2 C2 12731861 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mxx_2 PROBNOT 2 2 C2 C2 12731861 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mxy_1 PROBNOT 2 2 C2 C2 12872125 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mxy_2 PROBNOT 2 2 C2 C2 12872125 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mxz_1 PROBNOT 2 2 C2 C2 12872125 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1mxz_2 PROBNOT 2 2 C2 C2 12872125 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1my0_1 PROBNOT 2 2 C2 C2 12731861 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1my0_2 PROBNOT 2 2 C2 C2 12731861 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1my1_1 PROBNOT 2 2 C2 C2 12731861 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1my1_2 PROBNOT 2 2 C2 C2 12731861 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1my2_1 PROBNOT 2 2 C2 C2 12872125 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1my2_2 PROBNOT 2 2 C2 C2 12872125 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1my3_1 PROBNOT 2 2 C2 C2 12731861 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1my3_2 PROBNOT 2 2 C2 C2 12731861 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1my4_1 PROBNOT 2 2 C2 C2 12731861 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1my4_2 PROBNOT 2 2 C2 C2 12731861 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1my6 NO 2 2 C2 C2 12827458 12827458 INterface geometry conserved with 1isa (55%) 1my8_1 PROBNOT 1 1 NPS NPS 12526668 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1my8_2 PROBNOT 1 1 NPS NPS 12526668 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1myg_1 NO 1 1 NPS NPS 1390659 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1myg_2 NO 1 1 NPS NPS 1390659 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1myh_1 NO 1 1 NPS NPS 1390659 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1myh_2 NO 1 1 NPS NPS 1390659 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1myi_1 NO 1 1 NPS NPS 1390659 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1myi_2 NO 1 1 NPS NPS 1390659 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1myj_1 NO 1 1 NPS NPS 1905570 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1myj_2 NO 1 1 NPS NPS 1905570 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1mym NO 1 1 NPS NPS 8312263 8312263 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1myr NO 2 2 C2 C2 9195886 9195886 -- Annotation transfered from 1e70 1myt NO 1 1 NPS NPS 15299440 0 Myoglobin is well known to be monomeric 1myw PROBNOT 2 2 C2 C2 12370172 12370172 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 2emo 1myz NO 1 1 NPS NPS 12847289 12847289 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1mz0 YES 2 1 NS NPS 12847289 12847289 -- Supperposed structures 1mz4 NO 1 1 NPS NPS 12881497 12881497 Paper says: The cytochrome c-550 in T. elongatus also differs from that in Synechocystis 6803 and Arthrospira maxima in its lack of dimerization 1mza PROBNOT 1 1 NPS NPS 12384499 12384499 Paper says nothing, PISA says monomer -- Annotation transfered from 1mzd 1mzd PROBNOT 1 1 NPS NPS 12384499 12384499 Paper says nothing, PISA says monomer 1mze YES 2 2 NS C2 12432100 12432100 Paper says: Furthermore, the structure reveals the presence of a FIH-1 homodimer that forms in solution and is essential for FIH activity. 1mzf YES 2 2 NS C2 12432100 12432100 Paper says: Furthermore, the structure reveals the presence of a FIH-1 homodimer that forms in solution and is essential for FIH activity. -- Annotation transfered from 1mze 1mzh PROBNOT 2 2 C2 C2 0 0 INterface conserved with 1o0y (44%) 1mzj NO 2 2 C2 C2 12429097 12429097 1mzl PROBNOT 1 1 NPS NPS 7735835 7735835 Paper does not mention an oligomer and Wheat orthologue was found monomeric (12525478). -- Annotation transfered from 1fk1 1mzm PROBNOT 1 1 NPS NPS 7735835 7735835 Paper does not mention an oligomer and Wheat orthologue was found monomeric (12525478). -- Annotation transfered from 1fk1 1mzn_1 PROBNOT 2 2 C2 C2 11981034 10835357 BU changed since last release and is now corrected - - automaticaly inferred from 1fby 1mzn_2 PROBNOT 2 2 C2 C2 11981034 10835357 BU changed since last release and is now corrected - - automaticaly inferred from 1fby 1mzo NO 2 2 C2 C2 12454503 12454503 -- Annotation transfered from 3pfl 1mzs YES 1 2 NPS C2 12502353 12502353 1mzv NO 2 2 C2 C2 14726202 14726202 Paper implies dimer 1mzy NO 3 3 C3 C3 0 0 -- Annotation transfered from 1n70 1mzz NO 3 3 C3 C3 0 0 -- Annotation transfered from 1n70 1n00 NO 1 1 NPS NPS 12787021 12787021 Paper says: Elution profiles from gel filtration identified Anx(Gh1) as the annexin with the highest monomer content in this series and, coincidently, it is this protein which can be crystallized much more successfully than the other ones. -- annexins are a good example of proteins in an oligomeric equilibrium 1n0h NO 2 2 C2 C2 14557277 14557277 Paper says dimer -- Annotation transfered from 1jsc 1n0j NO 4 4 D2 D2 1394426 1394426 Paper says tetramer 1n0n NO 4 4 D2 D2 0 0 Paper says tetramer -- Annotation transfered from 1n0j 1n0t_1 PROBNOT 2 2 C2 C2 12519060 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1n0t_2 PROBNOT 2 2 C2 C2 12519060 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1n0y_1 NO 1 1 NPS NPS 14501118 10966818 - automatic transfer from 1exr 1n0y_2 NO 1 1 NPS NPS 14501118 10966818 - automatic transfer from 1exr 1n18_1 PROBNOT 2 2 C2 C2 12441104 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1n18_2 PROBNOT 2 2 C2 C2 12441104 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1n18_3 PROBNOT 2 2 C2 C2 12441104 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1n18_4 PROBNOT 2 2 C2 C2 12441104 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1n18_5 PROBNOT 2 2 C2 C2 12441104 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1n19 NO 2 2 C2 C2 12441104 12441104 Mammalian Cu,Zn SOD assembles into an unusually stable homodimer with exquisite substrate specificity. Interface conserved down to 50% (at least with 1jcv). Note that dimerization mode with prokariotic enzymes is different. 1n1a NO 2 2 C2 C2 12499534 12499534 Our research data (gel filtration and dynamic light scattering; data not shown) and previous articles have shown that FKBP52-N is a dimer in solution, while FKBP12 is a monomer 1n1b NO 2 2 C2 C2 12432096 12432096 PAper says dimer 1n1d_1 NO 2 2 C2 C2 14506262 10508782 interesting - family is hexameric but this protein is dimeric and active site is at the interface - (cf summary) - Given that I thought that evolutionary pathway is often the assembly one, this could be a counter example. - automatic transfer from 1coz 1n1d_2 NO 2 2 C2 C2 14506262 10508782 interesting - family is hexameric but this protein is dimeric and active site is at the interface - (cf summary) - Given that I thought that evolutionary pathway is often the assembly one, this could be a counter example. - automatic transfer from 1coz 1n1m NO 2 2 C2 C2 12483204 12483204 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. -- Annotation transfered from 1tkr 1n1q YES 4 12 NS Tetr 12767829 12767829 Interface geometry conserved with 1o9r (28%) 1n1x NO 1 1 NPS NPS 12833549 12833549 -- Annotation transfered from 1n3z 1n1z NO 2 2 C2 C2 12432096 12432096 PAper says dimer -- Annotation transfered from 1n1b 1n20 NO 2 2 C2 C2 12432096 12432096 PAper says dimer -- Annotation transfered from 1n1b 1n21 NO 2 2 C2 C2 12432096 12432096 PAper says dimer -- Annotation transfered from 1n1b 1n22 NO 2 2 C2 C2 12432096 12432096 PAper says dimer -- Annotation transfered from 1n1b 1n23 NO 2 2 C2 C2 12432096 12432096 PAper says dimer -- Annotation transfered from 1n1b 1n24 NO 2 2 C2 C2 12432096 12432096 PAper says dimer -- Annotation transfered from 1n1b 1n26 NA 2 2 NS C2 12461182 12461182 Paper says: The head-to-tail packing of two closely associated IL-6R molecules observed in the crystal may be representative of the configuration of the physiological dimer of IL-6R and provides new insight into the architecture of the IL-6R complex. 2d annotation (Dan): However its problematic (as usual): the dimer given by the BioUnit is not the same crystal dimer that is discussed in the paper. See figure 5. It seems that there can be many ways that an assembly can be wrong - we need more structured records to capture all those ways. 1n28_1 PROBNOT 1 1 NPS NPS 12501175 8979149 BU changed since last release and is now corrected - Human PLA predominantly exists as a monomer - automaticaly inferred from 1poe 1n28_2 PROBNOT 1 1 NPS NPS 12501175 8979149 BU changed since last release and is now corrected - Human PLA predominantly exists as a monomer - automaticaly inferred from 1poe 1n29 NO 1 1 NPS NPS 12501175 12501175 Human PLA predominantly exists as a monomer -- Annotation transfered from 1kqu 1n2a NO 2 2 C2 C2 14635120 14635120 Interface geometry conserved with 1e6b (23%) 1n2k NO 2 2 C2 C2 12888274 12888274 ASA exists as homodimer while at pH below 5.0 the enzyme exists as homooctamer, which may be treated as a tetramer of the dimers 1n2l NO 2 2 C2 C2 12888274 12888274 ASA exists as homodimer while at pH below 5.0 the enzyme exists as homooctamer, which may be treated as a tetramer of the dimers -- Annotation transfered from 1n2k 1n2n_1 PROBYES 2 1 C2 NPS 12464241 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1n2n_2 PROBYES 2 1 C2 NPS 12464241 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1n2s PROBNOT 2 2 C2 C2 12057193 12057193 PAper says: the observed magnesium dependency of RmlD collectively argue strongly that this dimer represents the physiologically active form of RmlD and is not a crystallization artifact. 1n2t NO 2 2 C2 C2 12386155 12386155 -- Annotation transfered from 1n31 1n31 NO 2 2 C2 C2 12386155 12386155 1n3b NA 3 3 C3 C3 12538896 12538896 NO info - ask crystollographers 1n3i NO 3 3 C3 C3 12755607 12755607 Paper says trimer -- Annotation transfered from 1g2o 1n3o NO 2 2 C2 C2 12595543 12595543 Implied in paper that it is a dimer, PISA also says that -- Annotation transfered from 1n3q 1n3p NO 2 2 C2 C2 12595543 12595543 Implied in paper that it is a dimer, PISA also says that -- Annotation transfered from 1n3q 1n3q NO 2 2 C2 C2 12595543 12595543 Implied in paper that it is a dimer, PISA also says that 1n3w PROBNOT 1 1 NPS NPS 12794084 12794084 EcoCyc says monomer -- Annotation transfered from 1nl5 1n3x PROBNOT 1 1 NPS NPS 12794084 12794084 EcoCyc says monomer -- Annotation transfered from 1nl5 1n3y PROBNOT 1 1 NPS NPS 12554829 12554829 Normally heterodimer 1n3z NO 1 1 NPS NPS 12833549 12833549 1n40 PROBNOT 1 1 NPS NPS 12435731 12435731 11304120 says P450s are monomeric enzymes 1n41 PROBNOT 1 1 NPS NPS 12401794 12401794 SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1n42 1n42 PROBNOT 1 1 NPS NPS 12401794 12401794 SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) 1n43 NO 4 4 D2 D2 12925786 12925786 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1n44 PROBNOT 1 1 NPS NPS 12401794 12401794 SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1n42 1n46 PROBYES 2 1 NS NPS 12565933 12565933 Other are monomers, papers says nothing and PISA says monomer. 1n47 NO 4 4 D2 D2 12586347 12586347 paper says tetramer 1n4f NO 1 1 NPS NPS 12777806 12777806 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1n4g PROBNOT 1 1 NPS NPS 12435731 12435731 11304120 says P450s are monomeric enzymes -- Annotation transfered from 1n40 1n4h NO 1 1 NPS NPS 12958591 12958591 Paper says: RORbeta can bind as a monomer to the sequence ANNTAGGTCA 1n4j NO 4 4 D2 D2 12925786 12925786 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1n4l PROBYES 2 1 C2 NPS 12818202 12818202 BU changed since last release and is now incorrect - -- Annotation transfered from 1qai 1n4o NA 2 2 C2 C2 0 0 1n51 NO 4 4 D2 D2 15388923 15388923 Paper says tetramer 1n55 NO 2 2 C2 C2 12522213 12522213 Interface geometry conserved with 1m6j (52%) - paper says dimer 1n57 NO 2 2 C2 C2 12621151 12621151 It is a homodimer but it is strange to see that the dimerization mode seems different from the one in 1izy (different surface but similar orientation). Interesting to investigate 1n5d NO 1 1 NPS NPS 11279087 11279087 Paper says monomer -- very very interesting for an evolution study: what is different in that enzyme? Would it be possible to re-engineer a dimer? / Or vice-versa? 1n5i NO 2 2 C2 C2 12662932 12662932 Homodimer -- Annotation transfered from 1mrn 1n5j NO 2 2 C2 C2 12662932 12662932 Homodimer -- Annotation transfered from 1mrn 1n5k NO 2 2 C2 C2 12662932 12662932 Homodimer -- Annotation transfered from 1mrn 1n5l NO 2 2 C2 C2 12662932 12662932 Homodimer -- Annotation transfered from 1mrn 1n5m NO 2 2 C2 C2 12505979 12505979 They explain in the paper why they observe a different crystal form without tetrameric assembly - interesting -- Annotation transfered from 1j07 1n5n_1 PROBNOT 1 1 NPS NPS 12823970 12126617 Paper says nothing although gel filtration mentioned. Related proteins are monomeric and PISA says monomer - automatic transfer from 1lry 1n5n_2 PROBNOT 1 1 NPS NPS 12823970 12126617 Paper says nothing although gel filtration mentioned. Related proteins are monomeric and PISA says monomer - automatic transfer from 1lry 1n5q NO 2 2 C2 C2 12514126 12514126 Interface geometry conserved with 1iuj (25%) -- Annotation transfered from 1lq9 1n5r NO 2 2 C2 C2 12505979 12505979 They explain in the paper why they observe a different crystal form without tetrameric assembly - interesting -- Annotation transfered from 1j07 1n5s NO 2 2 C2 C2 12514126 12514126 Interface geometry conserved with 1iuj (25%) -- Annotation transfered from 1lq9 1n5t NO 2 2 C2 C2 12514126 12514126 Interface geometry conserved with 1iuj (25%) -- Annotation transfered from 1lq9 1n5v NO 2 2 C2 C2 12514126 12514126 Interface geometry conserved with 1iuj (25%) -- Annotation transfered from 1lq9 1n5z_1 NA 1 1 NPS NPS 12453410 12453410 BU changed since last release and is now corrected - Paper says nothing, related proteins are monomers but PISA says tetramer - automaticaly inferred from 1jqq 1n5z_2 NA 1 1 NPS NPS 12453410 12453410 BU changed since last release and is now corrected - Paper says nothing, related proteins are monomers but PISA says tetramer - automaticaly inferred from 1jqq 1n68 PROBNOT 1 1 NPS NPS 12794077 12794077 Paper says nothing, PISA says monomer 1n6a PROBNOT 1 1 NPS NPS 12514135 12514135 Paper says all SET proteins are monomeric -- Annotation transfered from 1muf 1n6b PROBNOT 1 1 NPS NPS 12767218 12767218 11304120 says P450s are monomeric enzymes -- Annotation transfered from 1nr6 1n6c PROBNOT 1 1 NPS NPS 12514135 12514135 Paper says all SET proteins are monomeric -- Annotation transfered from 1muf 1n6h NO 1 1 NPS NPS 12433916 12433916 -- Annotation transfered from 1r2q 1n6i NO 1 1 NPS NPS 12433916 12433916 -- Annotation transfered from 1r2q 1n6k NO 1 1 NPS NPS 12433916 12433916 -- Annotation transfered from 1r2q 1n6l NO 1 1 NPS NPS 12433916 12433916 -- Annotation transfered from 1r2q 1n6m NO 2 2 C2 C2 14532111 14532111 Dimeric ncd with neck linker 1n6n NO 1 1 NPS NPS 12433916 12433916 -- Annotation transfered from 1r2q 1n6o NO 1 1 NPS NPS 12433916 12433916 -- Annotation transfered from 1r2q 1n6p NO 1 1 NPS NPS 12433916 12433916 -- Annotation transfered from 1r2q 1n6r NO 1 1 NPS NPS 12433916 12433916 -- Annotation transfered from 1r2q 1n6x PROBNOT 1 1 NPS NPS 12575941 12575941 -- Annotation transfered from 1az8 1n6y PROBNOT 1 1 NPS NPS 12575941 12575941 -- Annotation transfered from 1az8 1n70 NO 3 3 C3 C3 0 0 1n71_1 PROBNOT 2 2 C2 C2 12592013 10378269 BU changed since last release and is now corrected - 1bo4 (33% id) has similar domain geometry - automaticaly inferred from 1b87 1n71_2 PROBNOT 2 2 C2 C2 12592013 10378269 BU changed since last release and is now corrected - 1bo4 (33% id) has similar domain geometry - automaticaly inferred from 1b87 1n7e YES 1 2 NPS C2 12493751 12493751 interesting - same sequence, two dimerization modes! (1n7f) 1n7f NO 2 2 C2 C2 12493751 12493751 interesting - same sequence, two dimerization modes! (1n7e) 1n7g NO 4 4 D2 D2 12501186 12501186 Paper says tetramer 1n7h NO 4 4 D2 D2 12501186 12501186 Paper says tetramer -- Annotation transfered from 1n7g 1n7k NO 4 4 D2 D2 12529358 12529358 Paper says tetramer but surprisingly, it is different from the other tetrameric arrangment -- interesting convergent evolution? 1n7y NO 4 4 D2 D2 12925786 12925786 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1n83 NO 1 1 NPS NPS 12467577 12467577 Paper says: RORα LBD was shown to run as a monomer on native gels and by size exclusion chromatography (data not shown). 1n8f_1 PROBYES 2 4 C2 D2 12667068 10425687 BU changed since last release and is now incorrect - Interface geometry similar to 1oab (57%) - automaticaly inferred from 1qr7 1n8f_2 PROBYES 2 4 C2 D2 12667068 10425687 BU changed since last release and is now incorrect - Interface geometry similar to 1oab (57%) - automaticaly inferred from 1qr7 1n8k NO 2 2 C2 C2 12627956 12627956 -- Annotation transfered from 8adh 1n8p NO 4 4 D2 D2 12715888 12715888 yCGL exists as an α4 tetramer in solution (Yamagata et al., 1993) and in crystalline state. 1n8t NO 2 2 C2 C2 12595702 12595702 -- Annotation transfered from 1iat 1n92 NO 2 2 C2 C2 12627956 12627956 -- Annotation transfered from 8adh 1n9b PROBNOT 1 1 NPS NPS 12684014 12684014 -- Annotation transfered from 1ong 1n9f NO 1 1 NPS NPS 12777759 12777759 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1n9g YES 6 2 NS C2 12890667 0 BU changed since last release and is now incorrect - Interface geometry conserved with 1v3v (23%) - automaticaly inferred from 1gyr 1n9h NO 1 1 NPS NPS 12777759 12777759 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1n9i NO 1 1 NPS NPS 12777759 12777759 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1n9m NO 4 4 D2 D2 12925786 12925786 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1n9r NO 7 7 C7 C7 12618433 12618433 Paper says heptamer -- Annotation transfered from 1n9s_1 1n9s_1 NO 7 7 C7 C7 12618433 12618433 Paper says heptamer 1n9s_2 NO 7 7 C7 C7 12618433 12618433 Paper says heptamer -- Annotation transfered from 1n9s_1 1n9x NO 1 1 NPS NPS 12777759 12777759 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1n9y NO 4 4 D2 D2 12925786 12925786 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1n9z PROBNOT 1 1 NPS NPS 12611591 12611591 -- Annotation transfered from 1ido 1na5 PROBNOT 1 1 NPS NPS 12611591 12611591 -- Annotation transfered from 1ido 1na7 NO 1 1 NPS NPS 14646071 14646071 alpha2 beta2 - alpha not in contact -- Annotation transfered from 1pjk 1na8 PROBYES 2 1 C2 NPS 12808037 12808037 Fragment (150 aa of >600). SP says monomeric - paper says: we do not see any evidence for dimerization in solution by using either gel filtration or dynamic light scattering, suggesting that this is not an in vivo natural dimeric interaction. 1naa_1 NA 1 2 NPS C2 12493734 11786022 BU changed since last release and is now incorrect - Paper says that the enzyme is functional as a monomer, however they say it elutes in two peaks and the interface geometry seem conserved with 1cf3 (20% !). So dimer maybe relevant. - automaticaly inferred from 1kdg 1naa_2 NA 1 2 NPS C2 12493734 11786022 BU changed since last release and is now incorrect - Paper says that the enzyme is functional as a monomer, however they say it elutes in two peaks and the interface geometry seem conserved with 1cf3 (20% !). So dimer maybe relevant. - automaticaly inferred from 1kdg 1nag NO 1 1 NPS NPS 8518731 8518731 10731422 says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium - pH induced oligomerization -- Annotation transfered from 9pti 1nah NO 2 2 C2 C2 8611559 8611559 SP says homodimer -- Annotation transfered from 2udp 1nai NO 2 2 C2 C2 8611559 8611559 SP says homodimer -- Annotation transfered from 2udp 1nal NO 4 4 D2 D2 8081752 8081752 Interface geometry conserved with 1s5w (25%) -- Annotation transfered from 1fdy 1nap PROBNOT 4 4 D2 D2 7706245 7706245 Paper and PISA say tetramer -- Annotation transfered from 1tvx 1nas NO 2 2 C2 C2 9405351 9405351 paper says dimer -- Annotation transfered from 1oaa 1nat NO 1 1 NPS NPS 9335530 15255896 Spo0F is a monomer in both unphosphorylated and phosphorylated forms. 1nav NA 1 2 NPS C2 12699376 12699376 PISA finds a dimer, send email (johan.malm@karobio.se - Johan Malm) 1naw NA 4 2 C2 C2 8805592 8805592 Paper says that the protein dimerizes but the interface which they claim to be the right one is very small. 1nax PROBNOT 1 1 NPS NPS 12699376 12699376 Paper says nothing, related are monomeric and PISA says monomer -- Annotation transfered from 1q4x 1naz NO 1 1 NPS NPS 12777759 12777759 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1nb2 NO 6 6 D3 D3 12713952 12713952 1nba PROBNOT 4 4 D2 D2 1381445 1381445 Paper says tetramer - Interface geometry conserved with 1j2r (24%) -- interesting: very good example of QS evolution, clearly put in paper **** - again, same dimer -> tetramer and octamer + also found as a monomer + annotation via interf. geometry conservation 1nbb_1 PROBNOT 1 1 NPS NPS 8612077 15299853 Most cytochromes c prime are dimeric with each molecule comprising a left-handed four-a-helix bundle with a heme group attached to a Cys-X-X-Cys-His site near the carboxyl terminus. However, Rhodobacter capsulatus and R. sphaeroides cytochromes c prime appear to exist as equilibrium mixtures of monomers and dimers, and only R. palustris cytochrome c prime is completely monomeric(Cusanovich, 1971). - automatic transfer from 1cpr 1nbb_2 PROBNOT 1 1 NPS NPS 8612077 15299853 Most cytochromes c prime are dimeric with each molecule comprising a left-handed four-a-helix bundle with a heme group attached to a Cys-X-X-Cys-His site near the carboxyl terminus. However, Rhodobacter capsulatus and R. sphaeroides cytochromes c prime appear to exist as equilibrium mixtures of monomers and dimers, and only R. palustris cytochrome c prime is completely monomeric(Cusanovich, 1971). - automatic transfer from 1cpr 1nbc PROBYES 2 1 C2 NPS 8918451 8918451 Paper says nothing and PISA says monomer 1nbe NO 12 12 D3 D3 9680480 9680480 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1nbh NO 4 4 D2 D2 12859184 12859184 Paper says tetramer -- Annotation transfered from 1d2h 1nbi NO 4 4 D2 D2 12859184 12859184 Paper says tetramer -- Annotation transfered from 1d2h 1nbp PROBNOT 1 1 NPS NPS 12767230 0 BU changed since last release and is now corrected - - automaticaly inferred from 3ink 1nbq NO 2 2 C2 C2 12697893 12697893 Two hJAM1 molecules form a dimer that is stabilized by extensive ionic and hydrophobic contacts between the N-terminal domains. This dimeric arrangement is similar to that observed previously in the murine homolog of JAM1 (1f97, 60% id), indicating physiologic relevance. 1nbx NO 4 4 D2 D2 12925786 12925786 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1nc1 NO 2 2 C2 C2 12496243 12496243 Paper implies dimer - Dimer conserved with the dimer of the related hexameric form -- Annotation transfered from 1nc3 1nc3 NO 2 2 C2 C2 12496243 12496243 Paper implies dimer - Dimer conserved with the dimer of the related hexameric form 1nc6 PROBNOT 1 1 NPS NPS 12930148 12930148 -- Annotation transfered from 1az8 1nc9 NO 4 4 D2 D2 12925786 12925786 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1nce NO 2 2 C2 C2 12702803 12702803 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1ncj PROBNOT 1 1 NPS NPS 9655503 9655503 This structure, like its E-cadherin counterpart, does not adopt the strand dimer conformation. This suggests the possibility that classical cadherins might stably exist in both dimeric and monomeric forms. 1ncl NO 6 6 D3 D3 8663370 8663370 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1nco PROBYES 2 1 C2 NPS 8235619 8235619 I would guess from looking at the structure - Doug Rees said it was probably just a crystal contact. His guess is that the functional unit is a monomer. 1ncx PROBNOT 1 1 NPS NPS 15299599 0 1ncy PROBNOT 1 1 NPS NPS 15299599 0 -- Annotation transfered from 1ncx 1ncz PROBNOT 1 1 NPS NPS 15299599 0 -- Annotation transfered from 1ncx 1nd7 PROBNOT 1 1 NPS NPS 12535537 12535537 Paper says nothing, PISA says monomer 1nda_1 NO 2 2 C2 C2 8159665 10368274 Large interface and closely related dimer - automatic transfer from 1bzl 1nda_2 NO 2 2 C2 C2 8159665 10368274 Large interface and closely related dimer - automatic transfer from 1bzl 1ndc NO 6 6 D3 D3 8049207 8049207 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1nde PROBYES 1 2 NPS C2 12459017 12459017 -- Annotation transfered from 1hj1 1ndj NO 4 4 D2 D2 12925786 12925786 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1ndk NO 6 6 D3 D3 1324167 1324167 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1ndl NO 6 6 D3 D3 8081741 8081741 SP says hexamer 1ndo NO 6 6 C3 C3 9634695 9634695 Interface geometry conserved with 1ulj (28%) 1ndp NO 6 6 D3 D3 8286376 8286376 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1ndq NO 1 1 NPS NPS -1 0 -- Annotation transfered from 1c9n 1ndt NO 3 3 C3 C3 9735294 9735294 Active site at the monomer-monomer interface -- Annotation transfered from 1oe3 1ndu NO 1 1 NPS NPS -1 0 -- Annotation transfered from 1c9n 1ned NO 12 12 D6 D6 9177170 9177170 -- PISA is wrong here 1neg PROBNOT 1 1 NPS NPS 15185962 15185962 1nek YES 4 12 NPS C3 12560550 12560550 SP says trimer of a hetero-tetramer -- Annotation transfered from 1nen 1nel NO 2 2 C2 C2 8346189 8605183 Interface conserved with 1te6 (62% id) -- Annotation transfered from 1one 1nen YES 4 12 NPS C3 12560550 12560550 SP says trimer of a hetero-tetramer 1nes PROBNOT 1 1 NPS NPS 3640831 3640831 -- Annotation transfered from 1c1m 1neu PROBYES 2 1 C2 NPS 8816707 8816707 They find a tetramer but at a concentration above 100mg/ml!! Light scattering at ~1mg/ml gave someting in between monomer and dimer. But the problem is which dimer in the crystal then? So saying it is a monomer is probably safer. 1ney NO 2 2 C2 C2 12509510 12509510 Interface geometry conserved with 1m6j (43%) -- Annotation transfered from 7tim 1nf0 NO 2 2 C2 C2 12509510 12509510 Interface geometry conserved with 1m6j (43%) -- Annotation transfered from 7tim 1nf4 YES 16 24 NS Octa 12627224 12627224 Interface geometry conserved with 1jgc (32%) -- Annotation transfered from 1nfv 1nf6 YES 16 24 NS Octa 12627224 12627224 Interface geometry conserved with 1jgc (32%) -- Annotation transfered from 1nfv 1nf8 NO 2 2 C2 C2 12741825 12741825 PhzD is a dimer. Light scattering indicates a molecular mass of 49 400 ± 1100 Da, or approximately twice the monomer mass -- Annotation transfered from 1nf9 1nf9 NO 2 2 C2 C2 12741825 12741825 PhzD is a dimer. Light scattering indicates a molecular mass of 49 400 ± 1100 Da, or approximately twice the monomer mass 1nff NO 4 4 D2 D2 12524453 12524453 Paper says tetramer -- Annotation transfered from 1nfq 1nfg NO 4 4 D2 D2 12837777 12837777 Interface geometry conserved with 1gkr (33%) 1nfh NO 4 4 C2 C2 12730210 12730210 Tetramer proposed in the paper 1nfj NO 4 4 C2 C2 12730210 12730210 Tetramer proposed in the paper -- Annotation transfered from 1nfh 1nfq NO 4 4 D2 D2 12524453 12524453 Paper says tetramer 1nfr NO 4 4 D2 D2 12524453 12524453 Paper says tetramer -- Annotation transfered from 1nfq 1nfs PROBYES 2 1 C2 NPS 12540835 12540835 Seems to be a monomer - PISA would be wrong 1nfu PROBNOT 2 2 NPS NPS 12593649 12593649 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1nfv YES 16 24 NS Octa 12627224 12627224 Interface geometry conserved with 1jgc (32%) 1nfw PROBNOT 2 2 NPS NPS 12593649 12593649 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds 1nfx PROBNOT 2 2 NPS NPS 12593649 12593649 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1nfy PROBNOT 2 2 NPS NPS 12593649 12593649 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1nfz PROBYES 2 1 C2 NPS 12540835 12540835 Seems to be a monomer - PISA would be wrong -- Annotation transfered from 1nfs 1ng2 YES 1 2 NPS C2 12732142 12732142 Should be a domain swapped dimer -- Annotation transfered from 1uec 1nh0 NO 2 2 C2 C2 15056001 15056001 -- Annotation transfered from 1ajx 1nh6 PROBNOT 1 1 NPS NPS 12932195 12932195 -- Annotation transfered from 1ehn 1nh7 PROBYES 2 6 C2 D3 12511575 12511575 SP says: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme. - Even though dimer is correct, the hexamer is found in the crystal 1nh8 PROBYES 2 6 C2 D3 12511575 12511575 SP says: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme. - Even though dimer is correct, the hexamer is found in the crystal -- Annotation transfered from 1nh7 1nh9 YES 1 2 NPS C2 14627741 14627741 1nhb NO 1 1 NPS NPS 7612599 7612599 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1nhk NO 4 4 D2 D2 8263923 8263923 Equilibrium sedimentation studies are consistent with the enzyme being a tetramer in solution. -- Annotation transfered from 2nck 1nhp YES 1 4 NPS D2 7766608 7766608 Paper says it is tetrameric -- Annotation transfered from 1joa 1nhq YES 1 4 NPS D2 7766608 7766608 Paper says it is tetrameric -- Annotation transfered from 1joa 1nhr YES 1 4 NPS D2 7711038 8756456 Paper says it is tetrameric - automatic transfer from 1joa 1nhs YES 1 4 NPS D2 7711038 7711038 Paper says it is tetrameric -- Annotation transfered from 1joa 1nhu_1 PROBNOT 1 1 NPS NPS 12509436 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 1nhu_2 PROBNOT 1 1 NPS NPS 12509436 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 1nhv_1 PROBNOT 1 1 NPS NPS 12509436 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 1nhv_2 PROBNOT 1 1 NPS NPS 12509436 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 1nhz NA 1 1 NPS NPS 12686538 12686538 Paper talk about a homodimer - but might as well be a monomer - there is another homodimer proven to be functional (100% id) but different interaction ?! Very stange case - still interesting 1nia NO 3 3 C3 C3 7499203 7499203 -- Annotation transfered from 2nrd 1nib NO 3 3 C3 C3 7499203 7499203 -- Annotation transfered from 2nrd 1nic NO 3 3 C3 C3 7499203 7499203 - automatic transfer from 2nrd 1nid NO 3 3 C3 C3 7499203 7499203 -- Annotation transfered from 2nrd 1nie NO 3 3 C3 C3 7499203 7499203 -- Annotation transfered from 2nrd 1nif NO 3 3 C3 C3 7499203 7499203 -- Annotation transfered from 2nrd 1nio PROBNOT 1 1 NPS NPS 12876337 12876337 No info in papers, PISA says monomer 1nja NO 2 2 C2 C2 8611496 8611496 SP says homodimer -- Annotation transfered from 4tms 1njb NO 2 2 C2 C2 8611496 8611496 SP says homodimer -- Annotation transfered from 4tms 1njc NO 2 2 C2 C2 8611496 8611496 SP says homodimer -- Annotation transfered from 4tms 1njd NO 2 2 C2 C2 8611496 8611496 SP says homodimer -- Annotation transfered from 4tms 1nje NO 2 2 C2 C2 8611496 8611496 SP says homodimer -- Annotation transfered from 4tms 1njs_1 NO 1 1 NPS NPS 12755606 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1njs_2 NO 1 1 NPS NPS 12755606 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1nkd NO 2 2 C2 C2 10089502 10089502 Rop is a homodimeric RNA-binding protein (Polisky, 1988) 1nko PROBNOT 1 1 NPS NPS 14747738 14747738 Paper doesnt mention a dimer and PISA says monomer 1nkt NO 2 2 C2 C2 12606717 12606717 Dimeric form exists as said in paper 1nkv PROBNOT 3 3 C3 C3 0 0 No info, PISA says trimer and it seems correct (tight association) 1nl3 NO 2 2 C2 C2 12606717 12606717 Dimeric form exists as said in paper -- Annotation transfered from 1nkt 1nl5 PROBNOT 1 1 NPS NPS 12794084 12794084 EcoCyc says monomer 1nl6_1 NO 1 1 NPS NPS 11311061 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 1nl6_2 NO 1 1 NPS NPS 11311061 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 1nl7 NO 4 4 D2 D2 0 0 Paper says tetramer -- Annotation transfered from 1dm3 1nl9 PROBNOT 1 1 NPS NPS 12670229 12670229 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1nlf NO 6 6 C6 C6 12777796 12777796 Paper says hexamer 1nli PROBNOT 1 1 NPS NPS 12676436 12676436 No info, PISA says monomer -- Annotation transfered from 1mrk 1nlj_1 NO 1 1 NPS NPS 11311061 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 1nlj_2 NO 1 1 NPS NPS 11311061 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 1nlk YES 2 4 C2 D2 8263923 8263923 Equilibrium sedimentation studies are consistent with the enzyme being a tetramer in solution. 1nlr PROBYES 2 1 C2 NPS 9440876 9440876 Paper says nothing, PISA says monomer 1nls NO 4 4 D2 D2 -1 0 SP says tetramer -- Annotation transfered from 1cjp 1nlx NA 14 14 NS NS 0 0 No paper no info 1nly NO 6 6 C6 C6 12727865 12727865 PAper says hexamer -- Annotation transfered from 1nlz 1nlz NO 6 6 C6 C6 12727865 12727865 PAper says hexamer 1nm0 YES 1 4 NPS D2 14646074 14646074 Interface geometry conserved with 1m7s (40% id) -- Annotation transfered from 1e93 1nm6 PROBNOT 1 1 NPS NPS 12873514 12873514 -- Annotation transfered from 1doj 1nmk_1 PROBNOT 1 1 NPS NPS 12656618 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1nmk_2 PROBNOT 1 1 NPS NPS 12656618 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1nmt PROBYES 3 1 NS NPS 9501915 9501915 SP says monomer 1nmx NO 2 2 C2 C2 12614151 12614151 Seems well accepted that it is a dimer -- Annotation transfered from 1nn3 1nmy YES 1 2 NPS C2 12614151 12614151 Seems well accepted that it is a dimer -- Annotation transfered from 1e2f 1nmz NO 2 2 C2 C2 12614151 12614151 Seems well accepted that it is a dimer -- Annotation transfered from 1nn3 1nn0 NO 2 2 C2 C2 12614151 12614151 Seems well accepted that it is a dimer -- Annotation transfered from 1nn3 1nn1 NO 2 2 C2 C2 12614151 12614151 Seems well accepted that it is a dimer -- Annotation transfered from 1nn3 1nn2 PROBNOT 4 4 C4 C4 1920428 0 BU changed since last release and is now corrected - The paper does not describe the quaternary state. Comparision of the structure with 1ivd shows a very similar structure, and no ligand bound at the interface. So there is apparently no reason why the QS would differ. - automaticaly inferred from 1inw 1nn3 NO 2 2 C2 C2 12614151 12614151 Seems well accepted that it is a dimer 1nn5 NO 2 2 C2 C2 12614151 12614151 Seems well accepted that it is a dimer -- Annotation transfered from 1nn3 1nn6 PROBNOT 1 1 NPS NPS 12614156 12614156 Paper says nothing, PISA says monomer 1nn7 NO 4 4 C4 C4 12835418 12835418 Interface geometry conserved with 1t1d (40%) 1nnd NO 1 1 NPS NPS 15326591 15326591 Active as a monomer - Although HIV RT is active as a dimer (see ref) -- Annotation transfered from 1rw3 1nnf PROBNOT 1 1 NPS NPS 12533539 12533539 -- Annotation transfered from 1d9v 1nni PROBNOT 2 2 C2 C2 0 0 1nnj PROBNOT 1 1 NPS NPS 16243784 12065399 SP says monomer and a review says that these prots are monomeric -- Annotation transfered from 1tdz 1nnk NO 2 2 C2 C2 12593667 12593667 Paper says this dimer is real -- Annotation transfered from 1mqi 1nnp NO 2 2 C2 C2 12593667 12593667 Paper says this dimer is real -- Annotation transfered from 1mqi 1nnq NO 2 2 C2 C2 15468318 15468318 Swapped dimer 1nny PROBNOT 1 1 NPS NPS 12670229 12670229 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1no6 PROBNOT 1 1 NPS NPS 12670229 12670229 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1noa PROBNOT 1 1 NPS NPS 8477746 8477746 1noc_1 PROBYES 3 1 C3 NPS 9334294 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1nod YES 2 2 C2 C2 9516116 9516116 Wrong reconstruction -- Annotation transfered from 1dwv 1noi_1 PROBYES 2 2 C2 C2 8652510 9384557 Wrong interface of the dimer - automatic transfer from 2amv 1noi_2 PROBYES 2 2 C2 C2 8652510 9384557 Wrong interface of the dimer - automatic transfer from 2amv 1noj NO 2 2 C2 C2 8652510 8652510 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1nok NO 2 2 C2 C2 8652510 8652510 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1nol PROBYES 1 6 NPS D3 8518732 8518732 Paper says hexamer -- PISA doesnt find it -- Annotation transfered from 1lla 1non NO 4 4 D2 D2 15716449 15716449 PyrR eluted from high-performance liquid chromatography (HPLC) molecular sieving chromatography as a single symmetrical peak with an elution time corresponding to a native molecular weight of 77,000. This indicates that the native protein is a tetramer. In contrast, B. subtilis PyrR crystallized in hexameric and dimeric states, corresponding to molecular weights of 120,000 and 40,000, respectively (26), but migrated on gel filtration chromatography as though it had an intermediate molecular weight (27). This has been interpreted as resulting from rapid equilibration between the dimeric and hexameric states (27). Analysis of B. subtilis PyrR by HPLC under the same conditions used for B. caldolyticus PyrR yielded a molecular weight of 110,000 (21). The dimeric state of B. subtilis PyrR crystallized only in the presence of Sm2+, which fortuitously eliminated the hexamer by coordinating amino acid side chains at hexamer subunit contacts. It will be shown below that crystalline B. caldolyticus PyrR is a tetramer. - interesting story 1noo PROBNOT 1 1 NPS NPS -1 0 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1nop_1 PROBNOT 1 1 NPS NPS 12618186 11839309 Paper says monomer - automatic transfer from 1jy1 1nop_2 PROBNOT 1 1 NPS NPS 12618186 11839309 Paper says monomer - automatic transfer from 1jy1 1nos PROBNOT 1 1 NPS NPS 9334294 9334294 Dimerization impaired -- very interesting case of dimerization inhibition. 1np8 PROBYES 2 2 NS C2 14579356 14579356 1npa NO 2 2 C2 C2 9258349 9258349 -- Annotation transfered from 1ajx 1npd NO 2 2 C2 C2 12624088 12624088 -- Annotation transfered from 1vi2 1npf NO 1 1 NPS NPS 14517970 14517970 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1npg NO 1 1 NPS NPS 14517970 14517970 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1npj NO 3 3 C3 C3 12680761 12680761 -- Annotation transfered from 1as7 1npk NO 6 6 D3 D3 7966307 7966307 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1npn NO 3 3 C3 C3 12680761 12680761 -- Annotation transfered from 1as7 1npt NO 4 4 D2 D2 12569100 12569100 SP says homotetramer - papers too 1npv NO 2 2 C2 C2 12723947 12723947 -- Annotation transfered from 1ajx 1npw NO 2 2 C2 C2 12723947 12723947 -- Annotation transfered from 1ajx 1npx YES 1 4 NPS D2 1942054 1942054 Paper says it is tetrameric -- Annotation transfered from 1joa 1npz_1 PROBNOT 1 1 NPS NPS 12641451 12641451 SP says monomer - automatic transfer from 1nqc 1npz_2 PROBNOT 1 1 NPS NPS 12641451 12641451 SP says monomer - automatic transfer from 1nqc 1nq0 PROBNOT 1 1 NPS NPS 12511610 12511610 Paper says nothing, related are monomeric and PISA says monomer -- Annotation transfered from 1q4x 1nq1 PROBNOT 1 1 NPS NPS 12511610 12511610 Paper says nothing, related are monomeric and PISA says monomer -- Annotation transfered from 1q4x 1nq2 PROBNOT 1 1 NPS NPS 12554782 12554782 Paper says nothing, related are monomeric and PISA says monomer -- Annotation transfered from 1q4x 1nq3_1 NO 3 3 C3 C3 12925811 12925811 Interface conserved with 1jd1 (43% id) 1nq3_2 NO 3 3 C3 C3 12925811 12925811 Interface conserved with 1jd1 (43% id) -- Annotation transfered from 1nq3_1 1nq5_1 NO 4 4 D2 D2 12569100 12569100 SP says homotetramer - papers too - automatic transfer from 1npt 1nq7 NO 1 1 NPS NPS 14661742 14661742 Paper says: RORbeta can bind as a monomer to the sequence ANNTAGGTCA -- Annotation transfered from 1n4h 1nq9_1 PROBYES 1 2 NPS C2 12873131 15342247 BU changed since last release and is now incorrect - 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization - automaticaly inferred from 1jvq 1nq9_2 PROBYES 1 2 NPS C2 12873131 15342247 BU changed since last release and is now incorrect - 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization - automaticaly inferred from 1jvq 1nqa NO 4 4 D2 D2 12569100 12569100 SP says homotetramer - papers too -- Annotation transfered from 1npt 1nqb PROBNOT 6 6 D3 D3 9275175 9275175 Contact between trimer are probably relevant, although they say that the trimer seem to be the main specie. 1nqc PROBNOT 1 1 NPS NPS 12641451 12641451 SP says monomer 1nqk PROBNOT 4 4 D2 D2 0 0 Paper says: Here, we describe the crystal structure of E. coli alkanesulfonate monooxygenase SsuD, which in solution is a homotetrameric enzyme with a subunit molecular mass of 41,605 Da. - Interface geometry conserved with 1ezw (21%) -- Annotation transfered from 1m41 1nqm NO 4 4 D2 D2 12837778 12837778 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1nqn NO 4 4 D2 D2 12837778 12837778 Avidin is a clear tetramer -- Annotation transfered from 2cam 1nqo_1 NO 4 4 D2 D2 12569100 12569100 SP says homotetramer - papers too - automatic transfer from 1npt 1nqo_2 NO 4 4 D2 D2 12569100 12569100 SP says homotetramer - papers too - automatic transfer from 1npt 1nqy PROBNOT 1 1 NPS NPS 12837785 12837785 Paper seem to imply a monomer and PISA says monomer. -- Annotation transfered from 1nqz 1nqz PROBNOT 1 1 NPS NPS 12837785 12837785 Paper seem to imply a monomer and PISA says monomer. 1nr5_1 PROBNOT 2 2 C2 C2 12614613 12614613 Paper says dimer - Interface geometry conserved with 1ujn (38%) - automatic transfer from 1nvd 1nr5_2 PROBNOT 2 2 C2 C2 12614613 12614613 Paper says dimer - Interface geometry conserved with 1ujn (38%) - automatic transfer from 1nvd 1nr6 PROBNOT 1 1 NPS NPS 12899620 12899620 11304120 says P450s are monomeric enzymes 1nrf NO 1 1 NPS NPS 14596597 14596597 Paper says monomer 1nri PROBNOT 2 2 C2 C2 0 0 No paper - PISA says dimer 1nrv NO 2 2 C2 C2 12551896 12551896 Paper says: we show that the Grb10 SH2 domain and also full-length Grb10gamma are dimeric in solution under physiologic conditions. 1nrx PROBNOT 2 2 C2 C2 12614613 12614613 Paper says dimer - Interface geometry conserved with 1ujn (38%) -- Annotation transfered from 1nvd 1ns5 NO 2 2 C2 C2 0 0 Paper not available, SP says dimer - Interface geometry conserved with 1o6d (31%) 1nse NO 2 2 C2 C2 9875848 9875848 Clear dimer -- Annotation transfered from 1fol 1nsf NO 6 6 C6 C6 9731775 9731775 Paper says hexamer 1nsg_1 PROBNOT 1 1 NPS NPS 10089303 10425089 BU changed since last release and is now corrected - - automaticaly inferred from 1qpl 1nsi YES 4 2 C2 C2 10409685 10409685 1nsj NO 2 2 C2 C2 9166771 9166771 Interface conseved with 1v5x (42%) 1nsk NO 6 6 D3 D3 7658474 7658474 Hexamer of two different chains: A and B (A6, A5B, A4B2, A3B3, A2B4, AB5, B6) - interesting for Dmitry -- Annotation transfered from 1nue 1nsp NO 6 6 D3 D3 7669763 7669763 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1nsq NO 6 6 D3 D3 7669763 7669763 SP says hexamer -- Annotation transfered from 1ndl 1nst PROBNOT 1 1 NPS NPS 10196134 10196134 Paper says nothing, PISA and SP say monomer 1nsw YES 4 2 C2 C2 12837806 12837806 Interface conserved with 1erv (36%) -- since paper is not clear, interesting example of an added value of my work. 1nt1 PROBNOT 1 1 NPS NPS 12873514 12873514 -- Annotation transfered from 1doj 1ntd NO 3 3 C3 C3 7547950 7547950 -- Annotation transfered from 1as7 1nte PROBNOT 1 1 NPS NPS 12842047 12842047 SwissProt says is exists as monomer / dimer 1ntn NA 1 1 NPS NPS 8458425 0 This family of toxin is a mess in terms of oligomeric determination - I dont know 1nto_1 NO 4 4 D2 D2 12650918 14661950 SP says homodimer and homotetramer - equilibium? - automatic transfer from 1r37 1nto_2 NO 4 4 D2 D2 12650918 14661950 SP says homodimer and homotetramer - equilibium? - automatic transfer from 1r37 1nu5 NO 8 8 D4 D4 12930985 12930985 Paper says octamer 1nu6 NO 2 2 C2 C2 12906826 12906826 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. -- Annotation transfered from 1tkr 1nu8 NO 2 2 C2 C2 12906826 12906826 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. -- Annotation transfered from 1tkr 1nua PROBNOT 2 2 C2 C2 12614613 12614613 Paper says dimer - Interface geometry conserved with 1ujn (38%) -- Annotation transfered from 1nvd 1nuc NO 1 1 NPS NPS 8762134 8762134 Paper says monomeric -- Annotation transfered from 1ena 1nud_1 PROBNOT 1 1 NPS NPS 12679341 11980702 BU changed since last release and is now corrected - Paper says: the protein is a monomer in solution - automaticaly inferred from 1l9m 1nud_2 PROBNOT 1 1 NPS NPS 12679341 11980702 BU changed since last release and is now corrected - Paper says: the protein is a monomer in solution - automaticaly inferred from 1l9m 1nue NO 6 6 D3 D3 8747457 8747457 Hexamer of two different chains: A and B (A6, A5B, A4B2, A3B3, A2B4, AB5, B6) - interesting for Dmitry 1nuf NO 1 1 NPS NPS 12679341 12679341 11980702 says: the protein is a monomer in solution 1nug_1 PROBNOT 1 1 NPS NPS 12679341 11980702 BU changed since last release and is now corrected - Paper says: the protein is a monomer in solution - automaticaly inferred from 1l9m 1nug_2 PROBNOT 1 1 NPS NPS 12679341 11980702 BU changed since last release and is now corrected - Paper says: the protein is a monomer in solution - automaticaly inferred from 1l9m 1nuh NO 2 2 C2 C2 12777791 12777791 -- Annotation transfered from 1iat 1nul NO 4 4 D2 D2 9100006 9100006 XGPRT exists as a tetramer both in solution (as determined by gel-filtration studies; [Vos et al 1997]) and in the crystals. The subunit arrangement observed for XGPRT may explain why tetramers are required for enzyme function, since three of the four subunits may be contributing residues to each of the four active sites in the tetramer. More details in the paper -- Annotation transfered from 1a97 1nuo PROBNOT 1 1 NPS NPS 12554782 12554782 Paper says nothing, related are monomeric and PISA says monomer -- Annotation transfered from 1q4x 1nup NO 4 4 D2 D2 12574164 12574164 Paper says: hsPNAT-3 forms a tetramer, which is consistent with the deduced molecular weight from gel filtration chromatography -- Annotation transfered from 1nut 1nuq NO 4 4 D2 D2 12574164 12574164 Paper says: hsPNAT-3 forms a tetramer, which is consistent with the deduced molecular weight from gel filtration chromatography -- Annotation transfered from 1nut 1nur NO 4 4 D2 D2 12574164 12574164 Paper says: hsPNAT-3 forms a tetramer, which is consistent with the deduced molecular weight from gel filtration chromatography -- Annotation transfered from 1nut 1nus NO 4 4 D2 D2 12574164 12574164 Paper says: hsPNAT-3 forms a tetramer, which is consistent with the deduced molecular weight from gel filtration chromatography -- Annotation transfered from 1nut 1nut NO 4 4 D2 D2 12574164 12574164 Paper says: hsPNAT-3 forms a tetramer, which is consistent with the deduced molecular weight from gel filtration chromatography 1nuu NO 4 4 D2 D2 12574164 12574164 Paper says: hsPNAT-3 forms a tetramer, which is consistent with the deduced molecular weight from gel filtration chromatography -- Annotation transfered from 1nut 1nuw YES 1 4 NPS D2 12595528 12595528 -- Annotation transfered from 1nv6 1nux YES 1 4 NPS D2 12595528 12595528 -- Annotation transfered from 1nv6 1nuy YES 1 4 NPS D2 12595528 12595528 -- Annotation transfered from 1nv6 1nuz YES 1 4 NPS D2 12595529 12595529 -- Annotation transfered from 1nv6 1nv0 YES 1 4 NPS D2 12595529 12595529 -- Annotation transfered from 1nv6 1nv1 YES 1 4 NPS D2 12595529 12595529 -- Annotation transfered from 1nv6 1nv2 YES 1 4 NPS D2 12595529 12595529 -- Annotation transfered from 1nv6 1nv3 YES 1 4 NPS D2 12595529 12595529 -- Annotation transfered from 1nv6 1nv4 YES 1 4 NPS D2 12595529 12595529 -- Annotation transfered from 1nv6 1nv5 YES 1 4 NPS D2 12595529 12595529 -- Annotation transfered from 1nv6 1nv6 YES 1 4 NPS D2 12595529 12595529 1nv7 YES 2 4 C2 D2 12595529 12595529 1nv8_1 NO 1 1 NPS NPS 12741815 12741815 PrmC eluted at a volume consistent with a monomeric state. - automatic transfer from 1nv9 1nv8_2 NO 1 1 NPS NPS 12741815 12741815 PrmC eluted at a volume consistent with a monomeric state. - automatic transfer from 1nv9 1nv9 NO 1 1 NPS NPS 12741815 12741815 PrmC eluted at a volume consistent with a monomeric state. 1nva PROBNOT 2 2 C2 C2 12614613 12614613 Paper says dimer - Interface geometry conserved with 1ujn (38%) -- Annotation transfered from 1nvd 1nvb_1 PROBNOT 2 2 C2 C2 12614613 12614613 Paper says dimer - Interface geometry conserved with 1ujn (38%) - automatic transfer from 1nvd 1nvb_2 PROBNOT 2 2 C2 C2 12614613 12614613 Paper says dimer - Interface geometry conserved with 1ujn (38%) - automatic transfer from 1nvd 1nvd PROBNOT 2 2 C2 C2 12614613 12614613 Paper says dimer - Interface geometry conserved with 1ujn (38%) 1nvf_1 PROBNOT 2 2 C2 C2 12614613 12614613 Paper says dimer - Interface geometry conserved with 1ujn (38%) - automatic transfer from 1nvd 1nvf_2 PROBNOT 2 2 C2 C2 12614613 12614613 Paper says dimer - Interface geometry conserved with 1ujn (38%) - automatic transfer from 1nvd 1nvg NO 4 4 D2 D2 12650918 12650918 SP says homodimer and homotetramer - equilibium? -- Annotation transfered from 1r37 1nvk PROBNOT 1 1 NPS NPS 12860129 12860129 SP says monomer -- Annotation transfered from 1bgt 1nvq PROBNOT 1 1 NPS NPS 12244092 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization -- Annotation transfered from 1nvs 1nvr PROBNOT 1 1 NPS NPS 12244092 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization -- Annotation transfered from 1nvs 1nvs PROBNOT 1 1 NPS NPS 12244092 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization 1nvt NO 2 2 C2 C2 12906831 12906831 Interesting, sequence has diverged a lot but the dimer geometry is conserved. 1nw2_1 YES 4 2 D2 C2 12837806 12837806 BU changed since last release and is now incorrect - Interface conserved with 1erv (36%) -- since paper is not clear, interesting example of an added value of my work. - automaticaly inferred from 1nsw 1nw2_2 YES 4 2 D2 C2 12837806 12837806 BU changed since last release and is now incorrect - Interface conserved with 1erv (36%) -- since paper is not clear, interesting example of an added value of my work. - automaticaly inferred from 1nsw 1nw4 NO 6 6 D3 D3 14982926 14982926 Interface geometry conserved with 1vhj -- Annotation transfered from 1q1g 1nw5 NO 1 1 NPS NPS 12732637 12732637 Paper says: The most studied of these classes, type II restriction modification systems, usually have a dimeric endonuclease and a monomeric MTase that requires only the methyl-donating cofactor S-adenosyl-L-methionine (AdoMet) for activity. Here the MTase is of type II 1nw6 NO 1 1 NPS NPS 12732637 12732637 Paper says: The most studied of these classes, type II restriction modification systems, usually have a dimeric endonuclease and a monomeric MTase that requires only the methyl-donating cofactor S-adenosyl-L-methionine (AdoMet) for activity. Here the MTase is of type II -- Annotation transfered from 1nw5 1nw7 NO 1 1 NPS NPS 12732637 12732637 Paper says: The most studied of these classes, type II restriction modification systems, usually have a dimeric endonuclease and a monomeric MTase that requires only the methyl-donating cofactor S-adenosyl-L-methionine (AdoMet) for activity. Here the MTase is of type II -- Annotation transfered from 1nw5 1nw8 NO 1 1 NPS NPS 12732637 12732637 Paper says: The most studied of these classes, type II restriction modification systems, usually have a dimeric endonuclease and a monomeric MTase that requires only the methyl-donating cofactor S-adenosyl-L-methionine (AdoMet) for activity. Here the MTase is of type II -- Annotation transfered from 1nw5 1nwc NO 2 2 C2 C2 14559965 14559965 -- Annotation transfered from 1q2x 1nwe PROBNOT 1 1 NPS NPS 12733877 12733877 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1nwh NO 2 2 C2 C2 14559965 14559965 -- Annotation transfered from 1q2x 1nwi_1 NO 2 2 C2 C2 12705827 9826511 Paper and SP say dimer - automatic transfer from 7hbi 1nwi_2 NO 2 2 C2 C2 12705827 9826511 Paper and SP say dimer - automatic transfer from 7hbi 1nwk NO 1 1 NPS NPS 12813032 12813032 Actin exists in different states -- Annotation transfered from 1j6z 1nwl PROBNOT 1 1 NPS NPS 12733877 12733877 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1nwn NO 2 2 C2 C2 12705827 12705827 Paper and SP say dimer -- Annotation transfered from 7hbi 1nwo NA 2 1 C2 NPS 9761890 9761890 They speak about the dimer but no evidence is providen -- They say that a similar dimeric packing is observed in other crystal structures - azurin could be a good benchmark for assessing surface conservation. 1nwp NA 2 1 C2 NPS 9761890 9761890 They speak about the dimer but no evidence is providen -- They say that a similar dimeric packing is observed in other crystal structures - azurin could be a good benchmark for assessing surface conservation. -- Annotation transfered from 1nwo 1nwr_1 PROBNOT 1 1 NPS NPS 12851408 12775711 BU changed since last release and is now corrected - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1nwr_2 PROBNOT 1 1 NPS NPS 12851408 12775711 BU changed since last release and is now corrected - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1nwr_3 PROBNOT 1 1 NPS NPS 12851408 12775711 BU changed since last release and is now corrected - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1nwr_4 PROBNOT 1 1 NPS NPS 12851408 12775711 BU changed since last release and is now corrected - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1nws_1 PROBNOT 1 1 NPS NPS 12851408 12775711 BU changed since last release and is now corrected - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1nws_2 PROBNOT 1 1 NPS NPS 12851408 12775711 BU changed since last release and is now corrected - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1nws_3 PROBNOT 1 1 NPS NPS 12851408 12775711 BU changed since last release and is now corrected - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1nws_4 PROBNOT 1 1 NPS NPS 12851408 12775711 BU changed since last release and is now corrected - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1nwt_1 PROBNOT 1 1 NPS NPS 12851408 12775711 BU changed since last release and is now corrected - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1nwt_2 PROBNOT 1 1 NPS NPS 12851408 12775711 BU changed since last release and is now corrected - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1nwt_3 PROBNOT 1 1 NPS NPS 12851408 12775711 BU changed since last release and is now corrected - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1nwt_4 PROBNOT 1 1 NPS NPS 12851408 12775711 BU changed since last release and is now corrected - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1nwu_1 PROBNOT 1 1 NPS NPS 12851408 12775711 BU changed since last release and is now corrected - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1nwu_2 PROBNOT 1 1 NPS NPS 12851408 12775711 BU changed since last release and is now corrected - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1nwu_3 PROBNOT 1 1 NPS NPS 12851408 12775711 BU changed since last release and is now corrected - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1nwu_4 PROBNOT 1 1 NPS NPS 12851408 12775711 BU changed since last release and is now corrected - Paper does not speak about a dimer and its name, HCGP39 means 39-kDa human cartilage glycoprotein so it is very likely a monomer in solution. - automaticaly inferred from 1hjx 1nwz PROBNOT 1 1 NPS NPS 12872160 12872160 SP says monomer -- Annotation transfered from 1s1z 1nx0 NO 2 2 C2 C2 12684003 12684003 -- Annotation transfered from 1alv 1nx1 NO 2 2 C2 C2 12684003 12684003 -- Annotation transfered from 1alv 1nx2 NO 2 2 C2 C2 12684003 12684003 -- Annotation transfered from 1alv 1nx3 NO 2 2 C2 C2 12684003 12684003 -- Annotation transfered from 1alv 1nx6 YES 1 2 NPS C2 14559965 14559965 1nxb NA 1 1 NPS NPS 683181 683181 All papers are useless impossible to find an answer %$@~# -- Annotation transfered from 5ebx 1nxd_1 YES 1 4 NPS D2 15159564 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1qgl 1nxd_2 YES 1 4 NPS D2 15159564 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1qgl 1nxd_3 YES 1 4 NPS D2 15159564 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1qgl 1nxd_4 YES 1 4 NPS D2 15159564 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1qgl 1nxe NO 6 6 D3 D3 12741811 12741811 Paper says hexamer -- Annotation transfered from 1nxg 1nxf NO 2 2 C2 C2 12705827 12705827 Paper and SP say dimer -- Annotation transfered from 7hbi 1nxg NO 6 6 D3 D3 12741811 12741811 Paper says hexamer 1nxk_1 PROBNOT 1 1 NPS NPS 12791252 12791252 Paper says nothing about an oligomer - PISa says 12 subs ... wrong? (I think so) - automatic transfer from 1ny3 1nxk_2 PROBNOT 1 1 NPS NPS 12791252 12791252 Paper says nothing about an oligomer - PISa says 12 subs ... wrong? (I think so) - automatic transfer from 1ny3 1nxk_3 PROBNOT 1 1 NPS NPS 12791252 12791252 Paper says nothing about an oligomer - PISa says 12 subs ... wrong? (I think so) - automatic transfer from 1ny3 1nxk_4 PROBNOT 1 1 NPS NPS 12791252 12791252 Paper says nothing about an oligomer - PISa says 12 subs ... wrong? (I think so) - automatic transfer from 1ny3 1nxm NO 2 2 C2 C2 12791259 12791259 Interface geometry conserved with 1rtv (65%) 1nxo NO 2 2 C2 C2 15090529 15090529 When a protein solution of 1 to 2 mg/ml was used, the technique revealed the presence of a monomeric species alone, while using solutions of 5 to 10 mg/ml we observed a dimeric species. Higher concentrations revealed an equilibrium between dimeric, tetrameric, and octameric forms. - careful: different dimers use different faces - interesting -- Annotation transfered from 1nxw 1nxp NO 2 2 C2 C2 15090529 15090529 When a protein solution of 1 to 2 mg/ml was used, the technique revealed the presence of a monomeric species alone, while using solutions of 5 to 10 mg/ml we observed a dimeric species. Higher concentrations revealed an equilibrium between dimeric, tetrameric, and octameric forms. - careful: different dimers use different faces - interesting -- Annotation transfered from 1nxw 1nxq NO 4 4 D2 D2 12628239 12628239 paper says tetramer 1nxs NO 2 2 C2 C2 0 0 When a protein solution of 1 to 2 mg/ml was used, the technique revealed the presence of a monomeric species alone, while using solutions of 5 to 10 mg/ml we observed a dimeric species. Higher concentrations revealed an equilibrium between dimeric, tetrameric, and octameric forms. - careful: different dimers use different faces - interesting -- Annotation transfered from 1nxw 1nxt NO 2 2 C2 C2 15090529 15090529 When a protein solution of 1 to 2 mg/ml was used, the technique revealed the presence of a monomeric species alone, while using solutions of 5 to 10 mg/ml we observed a dimeric species. Higher concentrations revealed an equilibrium between dimeric, tetrameric, and octameric forms. - careful: different dimers use different faces - interesting -- Annotation transfered from 1nxw 1nxv NO 2 2 C2 C2 0 0 When a protein solution of 1 to 2 mg/ml was used, the technique revealed the presence of a monomeric species alone, while using solutions of 5 to 10 mg/ml we observed a dimeric species. Higher concentrations revealed an equilibrium between dimeric, tetrameric, and octameric forms. - careful: different dimers use different faces - interesting -- Annotation transfered from 1nxw 1nxw NO 2 2 C2 C2 15090529 15090529 When a protein solution of 1 to 2 mg/ml was used, the technique revealed the presence of a monomeric species alone, while using solutions of 5 to 10 mg/ml we observed a dimeric species. Higher concentrations revealed an equilibrium between dimeric, tetrameric, and octameric forms. - careful: different dimers use different faces - interesting 1nxx NO 2 2 C2 C2 0 0 When a protein solution of 1 to 2 mg/ml was used, the technique revealed the presence of a monomeric species alone, while using solutions of 5 to 10 mg/ml we observed a dimeric species. Higher concentrations revealed an equilibrium between dimeric, tetrameric, and octameric forms. - careful: different dimers use different faces - interesting -- Annotation transfered from 1nxw 1nxy PROBNOT 1 1 NPS NPS 12859188 12859188 EcoCyc says monomer -- Annotation transfered from 1jwp 1ny0 PROBNOT 1 1 NPS NPS 12859188 12859188 EcoCyc says monomer -- Annotation transfered from 1jwp 1ny3 PROBNOT 1 1 NPS NPS 12791252 12791252 Paper says nothing about an oligomer - PISa says 12 subs ... wrong? (I think so) 1nym PROBNOT 1 1 NPS NPS 12859188 12859188 EcoCyc says monomer -- Annotation transfered from 1jwp 1nyt YES 4 2 C2 C2 12637497 12637497 Said in the paper. Interessting to note that AroE (1p74) is supposedly a monomer (from the paper) but uses the same crystal contact as this protein! 1nyw NO 2 2 C2 C2 12791259 12791259 Interface geometry conserved with 1rtv (65%) -- Annotation transfered from 1nxm 1nyx NO 2 2 C2 C2 12672231 12672231 Paper says homodimer -- Annotation transfered from 1prg 1nyy PROBNOT 1 1 NPS NPS 12859188 12859188 EcoCyc says monomer -- Annotation transfered from 1jwp 1nz2 NO 1 1 NPS NPS 12644706 12644706 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1nz3 NO 1 1 NPS NPS 12644706 12644706 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1nz4 NO 1 1 NPS NPS 12644706 12644706 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1nz5 NO 1 1 NPS NPS 12644706 12644706 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1nz7 PROBNOT 1 1 NPS NPS 12749891 12749891 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1nza PROBNOT 3 3 C3 C3 0 0 1nzb YES 4 8 C4 C4 12954782 12954782 BU changed since last release and is now incorrect - -- Annotation transfered from 1kbu 1nzc_1 NO 2 2 C2 C2 12791259 12791259 Interface geometry conserved with 1rtv (65%) - automatic transfer from 1nxm 1nzc_2 NO 2 2 C2 C2 12791259 12791259 Interface geometry conserved with 1rtv (65%) - automatic transfer from 1nxm 1nzd PROBNOT 1 1 NPS NPS 12860129 12860129 SP says monomer -- Annotation transfered from 1bgt 1nzf PROBNOT 1 1 NPS NPS 12860129 12860129 SP says monomer -- Annotation transfered from 1bgt 1nzl_1 PROBNOT 1 1 NPS NPS 12706723 6254988 BU changed since last release and is now corrected - In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution - automaticaly inferred from 1a07 1nzl_2 PROBNOT 1 1 NPS NPS 12706723 6254988 BU changed since last release and is now corrected - In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution - automaticaly inferred from 1a07 1nzr_1 PROBYES 2 1 C2 NPS 15299800 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 1nzr_2 PROBYES 2 1 C2 NPS 15299800 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 1nzv_1 PROBNOT 1 1 NPS NPS 12706723 6254988 BU changed since last release and is now corrected - In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution - automaticaly inferred from 1a07 1nzv_2 PROBNOT 1 1 NPS NPS 12706723 6254988 BU changed since last release and is now corrected - In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution - automaticaly inferred from 1a07 1nzy PROBYES 6 3 D3 C3 8679561 11695894 BU changed since last release and is now incorrect - PISA says trimer so I ll rely on that - (paper says nothing) - automaticaly inferred from 1jxz 1o07_1 PROBNOT 1 1 NPS NPS 12904027 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1o07_2 PROBNOT 1 1 NPS NPS 12904027 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1o0a YES 6 3 C3 C3 12691752 14532280 SP says trimer -- Duplicated chains - automatic transfer from 1vjm 1o0f_1 PROBNOT 1 1 NPS NPS 14573867 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1o0f_2 PROBNOT 1 1 NPS NPS 14573867 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1o0h_1 PROBNOT 1 1 NPS NPS 14573867 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1o0h_2 PROBNOT 1 1 NPS NPS 14573867 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1o0m_1 PROBNOT 1 1 NPS NPS 14573867 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1o0m_2 PROBNOT 1 1 NPS NPS 14573867 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1o0n_1 PROBNOT 1 1 NPS NPS 14573867 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1o0n_2 PROBNOT 1 1 NPS NPS 14573867 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1o0o_1 PROBNOT 1 1 NPS NPS 14573867 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1o0o_2 PROBNOT 1 1 NPS NPS 14573867 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1o0r_1 PROBNOT 1 1 NPS NPS 12051854 12927542 Paper says nothing, PISA says monomer - automatic transfer from 1pzt 1o0r_2 PROBNOT 1 1 NPS NPS 12051854 12927542 Paper says nothing, PISA says monomer - automatic transfer from 1pzt 1o0y PROBNOT 2 2 C2 C2 0 0 INterface conserved with 1mzh (44%) 1o16 NO 1 1 NPS NPS 12939145 12939145 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1o1h PROBYES 2 4 C2 D2 0 0 1o20 YES 1 4 NPS D2 14705032 14705032 Interface geometry conserved with 1o9j (23%) 1o2d_1 PROBYES 1 2 NPS C2 14705036 16021622 BU changed since last release and is now incorrect - Interfave geometry conserved with 1rrm (31%) - automaticaly inferred from 1vhd 1o2d_2 PROBYES 1 2 NPS C2 14705036 16021622 BU changed since last release and is now incorrect - Interfave geometry conserved with 1rrm (31%) - automaticaly inferred from 1vhd 1o2e PROBNOT 1 1 NPS NPS 14529623 14529623 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution 1o2h PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2i PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2j PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2k PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2l PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2m PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2n PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2o PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2p PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2q PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2r PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2s PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2t PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2u PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2v PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2w PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2x PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2y PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o2z PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o30 PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o31 PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o32 PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o33 PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o34 PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o35 PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o36 PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o37 PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o38 PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o39 PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o3a PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o3b PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o3c PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o3d PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o3e PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o3f PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o3g PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o3h PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o3i PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o3j PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o3k PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o3l PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o3m PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o3n PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o3o PROBNOT 1 1 NPS NPS 12742021 12742021 -- Annotation transfered from 1az8 1o3w PROBNOT 1 1 NPS NPS 14529623 14529623 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1o2e 1o3y_1 PROBNOT 1 1 NPS NPS 12679809 7552752 BU changed since last release and is now corrected - Might form a dimer when anchored to the membrane but is monomeric in solution - automaticaly inferred from 1rrg 1o3y_2 PROBNOT 1 1 NPS NPS 12679809 7552752 BU changed since last release and is now corrected - Might form a dimer when anchored to the membrane but is monomeric in solution - automaticaly inferred from 1rrg 1o41 NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o42 NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o43 NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o44 NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o45 NO 1 1 NPS NPS 14613321 6254988 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution 1o46 NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o47 NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o48 NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o49 NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4a NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4b NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4c NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4d NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4e NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4f NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4g NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4h NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4i NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4j NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4k NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4l NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4m NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4n NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4o NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4p NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4q NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4r NO 1 1 NPS NPS 14613321 14613321 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1o4s NO 2 2 C2 C2 15103638 15103638 1o4t PROBNOT 2 2 C2 C2 15211523 15211523 Interface geometry conserved with 1vj2 (34%) 1o54 NO 4 4 D2 D2 0 0 Interface geometry conserved with 1i9g (30%) 1o58 PROBNOT 4 4 D2 D2 15211522 15211522 Paper says: The crystallographic packing in the TM0665 structure suggests that a tetramer is the biologically-relevant oligomeric form with a buried surface area of 2,802 Å2 per monomer. The prediction about the tetrameric nature of the O-acetylserine sulfhydrylase from Thermotoga maritima [Fig. 1(C)] is consistent with literature sources which indicate that the enzyme forms a homo-dimer or homo-tetramer. Tetrameric O-acetylserine sulfhydrylases have been previously observed in Saccharomyces cerevisiae,[4] Salmonella typhimurium,[5] and Arabidopsis thaliana[6] among others. 1o59 YES 1 6 NPS D3 15229895 15229895 Paper sys hexamer. The crystallographic packing in the YIR029W structure indicates that a hexamer is the biologically-relevant oligomeric form. A hexamer (200 kDa), composed of two trimers (100 kDa), has also been reported in biophysical studies with the allantoicase from Chlamydomonas reinhardtii 1o5i NO 4 4 D2 D2 0 0 no paper yet but the complex is so tight that it must be a true tetramer 1o5j PROBNOT 3 3 C3 C3 0 0 1o5k YES 2 4 C2 D2 0 0 Interface geometry conserved with 1dhp (42%) 1o5o PROBNOT 4 4 D2 D2 0 0 Coulnd find the real paper but 15752360 is the orthologous in another thermophile and it behaves as a tetramer. PISA also says tetramer 1o5q NO 4 4 D2 D2 14575713 14575713 Interface geometry conseved with 1s2u (30%) -- Annotation transfered from 1ujq 1o5x NO 2 2 C2 C2 14563846 14563846 Interface geometry conserved with 1m6j (43%) - paper says dimer -- Annotation transfered from 1m7p 1o60 NO 4 4 D2 D2 16021622 16021622 1o66 YES 5 10 C5 D5 16021622 16021622 Interface geometry conserved with 1m3u (52%) -- PQS gives the right decamer 1o68 YES 5 10 C5 D5 16021622 16021622 Interface geometry conserved with 1m3u (52%) -- PQS gives the right decamer -- Annotation transfered from 1o66 1o6b YES 1 6 NPS D3 16021622 16021622 PISA says hexamer - homologues are hexameric 1o6d YES 1 2 NPS C2 16021622 16021622 Interface geometry conserved with 1ns5 (31%) 1o6h PROBYES 3 1 C3 NPS 12747780 9295270 BU changed since last release and is now incorrect - Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer - automaticaly inferred from 1sqc 1o6j NA 2 2 NS NS 11752776 0 No paper, send email -- Annotation transfered from 1oc8 1o6k PROBNOT 1 1 NPS NPS 12434148 0 Paper says nothing about oligomer - PISA says monomer -- Annotation transfered from 1o6l 1o6l PROBNOT 1 1 NPS NPS 12434148 12434148 Paper says nothing about oligomer - PISA says monomer 1o6q PROBYES 3 1 C3 NPS 12747780 9295270 BU changed since last release and is now incorrect - Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer - automaticaly inferred from 1sqc 1o6r PROBYES 3 1 C3 NPS 12747780 9295270 BU changed since last release and is now incorrect - Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer - automaticaly inferred from 1sqc 1o6t PROBNOT 1 1 NPS NPS 12526809 12526809 BU changed since last release and is now corrected - Paper shows a monomer - automaticaly inferred from 1o6v 1o6v YES 2 1 NS NPS 12526809 12526809 Paper shows a monomer 1o6y PROBNOT 1 1 NPS NPS 12551895 12551895 A further step of gel filtration in a Superdex 75 column was performed to separate the monomeric protein from aggregated material. 1o6z NO 4 4 D2 D2 12581646 0 Paper says tetramer -- Annotation transfered from 2hlp 1o73 PROBNOT 1 1 NPS NPS 0 12707277 Paper says nothing, PISA says monomer 1o76 PROBYES 2 1 C2 NPS 12464241 0 1o79 PROBYES 3 1 C3 NPS 12747780 9295270 BU changed since last release and is now incorrect - Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer - automaticaly inferred from 1sqc 1o7e_1 NA 1 2 NPS C2 0 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1n4o 1o7e_2 NA 1 2 NPS C2 0 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1n4o 1o7g YES 2 6 NPS C3 12586937 0 Identical structures a hexameric - PISA says hexamer - Interface geometry conserved with 1ulj (28%) -- Annotation transfered from 1o7n 1o7h YES 2 6 NPS C3 12586937 0 Identical structures a hexameric - PISA says hexamer - Interface geometry conserved with 1ulj (28%) -- Annotation transfered from 1o7n 1o7k PROBYES 3 1 C3 NPS 12356722 12356722 Author said: The three-fold symmetry of our structure is intriguing, but I know of no experiment evidence to suggest that the intact protein is a trimer. The intact protein is maintained in an inactive conformation until it is activated by phosphorylation. I had thought that the trimer might be part of the mechanism that prevents it from binding lipids until it is activated. However, this is a proposition that we never pursued. In light of any evidence for a biological significance, we did not comment on the symmetry. 1o7m YES 2 6 NPS C3 12586937 0 Identical structures a hexameric - PISA says hexamer - Interface geometry conserved with 1ulj (28%) -- Annotation transfered from 1o7n 1o7n YES 2 6 NPS C3 12586937 12586937 Identical structures a hexameric - PISA says hexamer - Interface geometry conserved with 1ulj (28%) 1o7p YES 2 6 NPS C3 12586937 0 Identical structures a hexameric - PISA says hexamer - Interface geometry conserved with 1ulj (28%) -- Annotation transfered from 1o7n 1o7s PROBNOT 1 1 NPS NPS 12438315 0 Paper doesnt mention a dimer and PISA says monomer -- Annotation transfered from 1nko 1o7u PROBNOT 1 1 NPS NPS 0 0 Paper says that protein is in an oxidized state (no S-S). -- Annotation transfered from 1ezk 1o7v PROBNOT 1 1 NPS NPS 12438315 0 Paper doesnt mention a dimer and PISA says monomer -- Annotation transfered from 1nko 1o7w YES 2 6 NPS C3 12586937 0 Identical structures a hexameric - PISA says hexamer - Interface geometry conserved with 1ulj (28%) -- Annotation transfered from 1o7n 1o7x YES 4 2 C2 C2 12473121 12473121 BU changed since last release and is now incorrect - Interface geometry conserved with 1a59 (33%) 1o7y PROBNOT 4 4 D2 D2 12737818 12737818 These proteins are ineresting: this one forms a tetramer similar to 1plf (41%) and which is known to form tetramers in solution. It seems however that this prot does not form tetramers in solution: Analytical ultracentrifugation indicates that, in free solution, IP-10 exists in a monomer-dimer equilibrium with a dissociation constant of 9 μM. We propose that the tetrameric structures may represent species promoted by the binding of glycosaminoglycans. -- interesting for evolution study 1o7z NO 2 2 C2 C2 12737818 0 These proteins are ineresting: this one forms a dimer which is found in 1plf (41%) and which is known to form tetramers in solution. It seems however that this prot does not form tetramers in solution: Analytical ultracentrifugation indicates that, in free solution, IP-10 exists in a monomer-dimer equilibrium with a dissociation constant of 9 μM. We propose that the tetrameric structures may represent species promoted by the binding of glycosaminoglycans. -- interesting for evolution study -- Annotation transfered from 1o80 1o80 NO 2 2 C2 C2 12737818 12737818 These proteins are ineresting: this one forms a dimer which is found in 1plf (41%) and which is known to form tetramers in solution. It seems however that this prot does not form tetramers in solution: Analytical ultracentrifugation indicates that, in free solution, IP-10 exists in a monomer-dimer equilibrium with a dissociation constant of 9 μM. We propose that the tetrameric structures may represent species promoted by the binding of glycosaminoglycans. -- interesting for evolution study 1o81 NA 2 2 NS NS 11752776 0 No paper, send email -- Annotation transfered from 1oc8 1o85 PROBNOT 1 1 NPS NPS 0 0 Paper says that protein is in an oxidized state (no S-S). -- Annotation transfered from 1ezk 1o89 NO 2 2 C2 C2 15388933 0 Interface geometry conserved with 1v3v (28%) 1o8b NO 2 2 C2 C2 12517338 0 Interface geometry conserved with 1uj6 (40%) -- Annotation transfered from 1lkz 1o8c_1 NO 2 2 C2 C2 15388933 0 Interface geometry conserved with 1v3v (28%) - automatic transfer from 1o89 1o8c_2 NO 2 2 C2 C2 15388933 0 Interface geometry conserved with 1v3v (28%) - automatic transfer from 1o89 1o8n NO 3 3 C3 C3 12590921 0 Interface geometry conserved with 1jlj (52%) -- Annotation transfered from 1uux 1o8o NO 3 3 C3 C3 12590921 0 Interface geometry conserved with 1jlj (52%) -- Annotation transfered from 1uux 1o8q YES 8 3 NS C3 12590921 0 Interface geometry conserved with 1jlj (52%) 1o8u NO 6 6 D3 D3 12421807 12421807 1o8v PROBNOT 1 1 NPS NPS 12818189 12818189 Paper says nothing, PISA says monomer 1o8w PROBNOT 1 1 NPS NPS 12707277 0 Paper says that protein is in an oxidized state (no S-S). -- Annotation transfered from 1ezk 1o8x PROBNOT 1 1 NPS NPS 0 0 Paper says that protein is in an oxidized state (no S-S). -- Annotation transfered from 1ezk 1o90 NO 4 4 D2 D2 12888348 0 BU changed since last release and is now corrected - Paper says tetramer. But MAT-III is dimeric -- Annotation transfered from 1o92 1o91 NO 3 3 C3 C3 12782141 0 Interface geometry conserved with 1gr3 (56%) 1o92 NO 4 4 D2 D2 12888348 12888348 BU changed since last release and is now corrected - Paper says tetramer. But MAT-III is dimeric 1o93 NO 4 4 D2 D2 12888348 0 BU changed since last release and is now corrected - Paper says tetramer. But MAT-III is dimeric -- Annotation transfered from 1o92 1o9b NO 2 2 C2 C2 12637497 0 -- Annotation transfered from 1vi2 1o9c YES 1 2 NPS C2 12606564 0 Interface geometry conserved with 1a37 (65%) 1o9d YES 1 2 NPS C2 12606564 0 Interface geometry conserved with 1a37 (65%) -- Annotation transfered from 1o9c 1o9e YES 1 2 NPS C2 12606564 0 Interface geometry conserved with 1a37 (65%) -- Annotation transfered from 1o9c 1o9f YES 1 2 NPS C2 12606564 0 Interface geometry conserved with 1a37 (65%) -- Annotation transfered from 1o9c 1o9j NO 4 4 D2 D2 12693930 0 Interface geometry conserved with 1uxr (31%) 1o9l YES 4 2 NS C2 0 0 Pig heart SCOT can exist as both a dimer and a tetramer (Rochet et al., 2000) 1o9r YES 6 12 NS Tetr 12660233 0 Interface geometry conserved with 1dps (55%) 1o9s YES 2 1 NS NPS 0 0 PID 12567185 says all SET proteins are monomeric 1o9t NO 4 4 D2 D2 12888348 0 BU changed since last release and is now corrected - Paper says tetramer. But MAT-III is dimeric -- Annotation transfered from 1o92 1o9u YES 1 2 NPS C2 12554650 11440715 Paper says dimer detected in solution but the functional significance is unclear (autoinhibition is a possibility) - monomer/dimer equilibrium 1oa2 YES 6 1 C2 NPS 12649442 0 In dynamic light-scattering analysis the protein appears only as a monomer -- Annotation transfered from 1h8v 1oa3 PROBYES 4 1 NS NPS 12649442 12649442 1oa4 PROBNOT 1 1 NPS NPS 12649442 0 1oa8 PROBYES 4 1 NS NPS 14583607 14583607 Paper implies monomer 1oaa NO 2 2 C2 C2 9405351 9405351 paper says dimer 1oab YES 2 4 C2 D2 15019786 15019786 Paper says tetramer - Interface geometry similar to 1qr7 (57%) 1oad PROBYES 2 4 C2 D2 12777803 0 -- Annotation transfered from 1o1h 1oae_1 NA 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - Found during the 3D complex curation - automaticaly inferred from 1gu2 1oae_2 NA 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - Found during the 3D complex curation - automaticaly inferred from 1gu2 1oah NO 2 2 C2 C2 12618432 12618432 Paper says: Biochemical studies suggest that the homodimer is the functional form of the catalytic unit -- SCOP error in dom arch? 1oaj NO 1 1 NPS NPS 12595249 12595249 Depletion of copper and zinc dissociates the two mutant proteins into monomers, which reassemble toward the dimeric state upon addition of stoichiometric amounts of zinc -- very interessting example for induced dimerization 1oal NO 1 1 NPS NPS 12595249 0 Depletion of copper and zinc dissociates the two mutant proteins into monomers, which reassemble toward the dimeric state upon addition of stoichiometric amounts of zinc -- very interessting example for induced dimerization -- Annotation transfered from 1oaj 1oan NO 2 2 C2 C2 12759475 12759475 14737159 says: A three-dimensional structure of the soluble E ectodomain (sE) in its trimeric, postfusion state reveals striking differences from the dimeric, prefusion form. 1oas NO 2 2 C2 C2 9761678 9761678 Paper says: O-Acetylserine sulfhydrylase (EC 4.2.99.8) is a homodimeric pyridoxal 5′-phosphate (PLP)-dependent enzyme with a subunit molecular mass of 34,450 [Byrne et al 1988]. -- Annotation transfered from 1d6s 1oat PROBYES 4 2 C2 C2 9514741 9514741 Although the paper mentions an hexamer found in the crystal no evidence is shown that is exists in solution. 1ob0 PROBNOT 1 1 NPS NPS 12540849 0 SP says monomer -- Annotation transfered from 1bli 1ob2 PROBNOT 1 1 NPS NPS 0 9838020 BU changed since last release and is now corrected - EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa. - automaticaly inferred from 1dg1 1ob5 PROBYES 3 1 C3 NPS 16257965 9838020 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa. - automaticaly inferred from 1ha3_1 1obf YES 2 4 C2 D2 12777799 12777799 Paper says: The global structure of the enzyme has a homotetrameric quaternary structure similar to that observed for its bacterial and eukaryotic counterparts. 1obm NO 1 1 NPS NPS 9545280 9545280 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1obn PROBNOT 1 1 NPS NPS 12622704 0 No info was found, PISA says monomer. I also think it should be. -- Annotation transfered from 1uzw 1obo PROBYES 2 1 NS NPS 12682068 12682068 From the paper they seem to assume it is a monomer. 1obp NO 2 2 C2 C2 8901871 8901871 Domain Swapped dimer -- Annotation transfered from 1gt1 1obq PROBNOT 2 2 C2 C2 12832753 0 SP says: Oligomer; Can form dimers (beta-crustacyanin); or complexes of 16 subunits (alpha-crustacyanin). There are five types of subunits: A1, A2, A3, C1 and C2 -- Annotation transfered from 1s2p 1obs NO 2 2 C2 C2 8780513 8780513 Blocked ricin undergoes a pH-dependent reversible self-association, being predominantly dimeric at neutral pH and monomeric at acidic pH. -- Annotation transfered from 1uq5 1obt NO 2 2 C2 C2 8780513 8780513 Blocked ricin undergoes a pH-dependent reversible self-association, being predominantly dimeric at neutral pH and monomeric at acidic pH. -- Annotation transfered from 1uq5 1obu PROBNOT 2 2 C2 C2 12832753 0 SP says: Oligomer; Can form dimers (beta-crustacyanin); or complexes of 16 subunits (alpha-crustacyanin). There are five types of subunits: A1, A2, A3, C1 and C2 -- Annotation transfered from 1s2p 1obv PROBNOT 1 1 NPS NPS 12682068 0 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1ftg 1obw NO 6 6 D3 D3 9201917 9201917 SP and EcoCyc say hexamer -- Annotation transfered from 1mjz 1obx PROBYES 2 1 C2 NPS 12842047 0 BU changed since last release and is now incorrect - SwissProt says is exists as monomer / dimer -- Annotation transfered from 1nte 1oby YES 2 1 C2 NPS 12842047 12842047 Fragment - The interface of the two domains is found on the same face were the peptide (representing a protein) is bound. So normally, there should not be a dimer (the bound protein should prevent it). 1oc1 PROBNOT 1 1 NPS NPS 12622704 0 No info was found, PISA says monomer. I also think it should be. -- Annotation transfered from 1uzw 1oc2 NO 2 2 C2 C2 14505409 0 Paper says dimer -- Annotation transfered from 1ket 1oc3_1 YES 1 2 NPS C2 15046979 11518528 BU changed since last release and is now incorrect - Interface geometry conserved with 1psq (30%) - automatic transfer from 1h4o_2 1oc3_2 YES 1 2 NPS C2 15046979 11518528 BU changed since last release and is now incorrect - Interface geometry conserved with 1psq (30%) - automatic transfer from 1h4o_2 1oc3_3 YES 1 2 NPS C2 15046979 11518528 BU changed since last release and is now incorrect - Interface geometry conserved with 1psq (30%) - automatic transfer from 1h4o_2 1oc4 YES 4 3 D2 D2 12967707 12967707 BU changed since last release and is now incorrect - As noted for many other LDH structures, lactate dehydrogenase from P. berghei forms a tetramer both in solution and in crystals. 1oc5 PROBNOT 1 1 NPS NPS 12842048 0 Paper says nothing, PISA says monomer -- Annotation transfered from 1oc6 1oc6 PROBNOT 1 1 NPS NPS 12842048 12842048 Paper says nothing, PISA says monomer 1oc7 PROBNOT 1 1 NPS NPS 12842048 0 Paper says nothing, PISA says monomer -- Annotation transfered from 1oc6 1oc8 NA 2 2 NS NS 0 0 No paper, send email 1oc9 NA 2 2 NS NS 0 0 No paper, send email - automatic transfer from 1oc8 1ocb PROBYES 2 1 NS NPS 12842048 12842048 BU changed since last release and is now incorrect - Paper says nothing, PISA says monomer 1oce PROBNOT 1 1 NPS NPS 10231521 10231521 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1ocj PROBNOT 1 1 NPS NPS 12842048 0 Paper says nothing, PISA says monomer -- Annotation transfered from 1oc6 1ocn PROBNOT 1 1 NPS NPS 12744312 0 Paper says nothing, PISA says monomer -- Annotation transfered from 1oc6 1ocs PROBNOT 1 1 NPS NPS 14514667 14514667 Gel filtration of the purified protein showed that it elutes as a monomer in absence of ligand (the apo-protein structure has one molecule bound in the asymmetric unit). We suppose that dimerization in the presence of the ligand is probably induced by the crystallization conditions. 1oct NO 1 1 NPS NPS 8156594 8156594 Monomer due to the DNA segment size. 1ocu PROBYES 2 1 C2 NPS 14514667 14514667 BU changed since last release and is now incorrect - Gel filtration of the purified protein showed that it elutes as a monomer in absence of ligand (the apo-protein structure has one molecule bound in the asymmetric unit). We suppose that dimerization in the presence of the ligand is probably induced by the crystallization conditions. - automaticaly inferred from 1ocs 1ocv PROBYES 4 2 C2 C2 12734184 0 1ocx NO 3 3 C3 C3 12731863 0 Interface geometry conserved with 1kkr (43%) 1od1 PROBNOT 1 1 NPS NPS 12777758 0 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1od2 NO 2 2 C2 C2 12663926 0 Paper says: These mutant proteins are still dimeric in solution as determined by light-scattering experiments (data not shown). -- Annotation transfered from 1uyr 1od4 YES 3 2 NS C2 12663926 0 cf. 1uyr 1od5 NO 6 6 D3 D3 12771376 12771376 BU changed since last release and is now corrected - Paper says hexamer 1od6 YES 1 6 NPS D3 14684898 14684898 BU changed since last release and is now incorrect - Paper and PISA say hexamer - trimer and hexamer could be in equilibrium - paper compares stability of mesophile vs. thermo - interesting 1od7 PROBNOT 1 1 NPS NPS 12737821 0 Paper doesnt mention a dimer and PISA says monomer -- Annotation transfered from 1qfp 1od8 PROBNOT 1 1 NPS NPS 12744311 0 Seems to be monomeric although there is no clear evidence -- Annotation transfered from 1v0k 1od9 PROBNOT 1 1 NPS NPS 12737821 0 Paper doesnt mention a dimer and PISA says monomer -- Annotation transfered from 1qfp 1oda PROBNOT 1 1 NPS NPS 12737821 0 Paper doesnt mention a dimer and PISA says monomer -- Annotation transfered from 1qfp 1odb YES 6 2 C2 C2 12777802 12777802 1odc PROBYES 1 4 NPS NA 16942022 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 1odi NO 6 6 D3 D3 15046984 0 Interface geometry conserved with 1q1g (28%) -- Annotation transfered from 1odl 1odj NO 6 6 D3 D3 0 0 Interface geometry conserved with 1q1g (28%) -- Annotation transfered from 1odl 1odk NO 6 6 D3 D3 15046984 0 Interface geometry conserved with 1q1g (28%) -- Annotation transfered from 1odl 1odl NO 6 6 D3 D3 15046984 0 Interface geometry conserved with 1q1g (28%) 1odm PROBNOT 1 1 NPS NPS 12926272 0 No info was found, PISA says monomer. I also think it should be. -- Annotation transfered from 1uzw 1odn PROBNOT 1 1 NPS NPS 12926272 0 No info was found, PISA says monomer. I also think it should be. -- Annotation transfered from 1uzw 1odo PROBNOT 1 1 NPS NPS 14691240 14691240 Paper actually compares this structure to 1gwi but does not speak at all about the oligomeric state. PISA says monomer 1ods_1 NO 6 6 D3 D3 12842474 12842474 BU changed since last release and is now corrected - The purified protein is a hexamer in solution, as revealed by ultra-centrifugation 1ods_2 NO 6 6 D3 D3 12842474 12842474 BU changed since last release and is now corrected - The purified protein is a hexamer in solution, as revealed by ultra-centrifugation 1odt NO 6 6 D3 D3 12842474 12842474 BU changed since last release and is now corrected - The purified protein is a hexamer in solution, as revealed by ultra-centrifugation 1odv_1 PROBNOT 1 1 NPS NPS 12639952 15159559 BU changed since last release and is now corrected - Sp says monomer - automaticaly inferred from 1ot9 1odv_2 PROBNOT 1 1 NPS NPS 12639952 15159559 BU changed since last release and is now corrected - Sp says monomer - automaticaly inferred from 1ot9 1odw NO 2 2 C2 C2 -1 0 -- Annotation transfered from 1ajx 1odx NO 2 2 C2 C2 -1 0 -- Annotation transfered from 1ajx 1ody NO 2 2 C2 C2 9827997 9083478 - automatic transfer from 1ajx 1odz_1 PROBNOT 1 1 NPS NPS 12841226 0 BU changed since last release and is now corrected - 1odz_2 PROBNOT 1 1 NPS NPS 12841226 0 BU changed since last release and is now corrected - 1oe1 YES 1 3 NPS C3 12691751 0 -- Annotation transfered from 1haw 1oe2 YES 1 3 NPS C3 12691751 0 -- Annotation transfered from 1haw 1oe3 NO 3 3 C3 C3 12691751 0 Active site at the monomer-monomer interface 1oe4 PROBYES 2 1 NS NPS 12820976 0 No oligomer mentioned - PISA says monomer and indeed the contact is very small -- Annotation transfered from 1oe5 1oe5 PROBYES 2 1 NS NPS 12820976 12820976 No oligomer mentioned - PISA says monomer and indeed the contact is very small 1oe6 PROBYES 2 1 NS NPS 12820976 0 No oligomer mentioned - PISA says monomer and indeed the contact is very small -- Annotation transfered from 1oe5 1oe7 NO 2 2 C2 C2 12939136 0 -- Annotation transfered from 1oe8 1oe8 NO 2 2 C2 C2 12939136 0 1oeb NO 2 2 C2 C2 12773374 0 Interestingly, the SH3C displays ion-dependent dimerization in the crystal and in solution, suggesting a novel mechanism for the regulation of SH3 domain functions. 1oec PROBYES 4 1 D2 NPS 0 0 BU changed since last release and is now incorrect - No paper - Tyrosine kinase receptor, so dimeriization is triggered by ligand binding but monomeric form exists - automatic transfer from 1gjo 1oel NO 14 14 D7 D7 8846220 8846220 -- Annotation transfered from 1kp8 1oem PROBNOT 1 1 NPS NPS 12802338 0 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1oen NO 1 1 NPS NPS 8609605 8609605 Paper says: E. coli PCK is a monomeric, globular protein -- Annotation transfered from 1os1 1oeo PROBNOT 1 1 NPS NPS 12802338 0 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1oes PROBNOT 1 1 NPS NPS 12802339 0 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1oet PROBNOT 1 1 NPS NPS 12802339 0 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1oeu PROBNOT 1 1 NPS NPS 12802339 0 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1oev PROBNOT 1 1 NPS NPS 12802339 0 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1oew PROBNOT 1 1 NPS NPS 0 0 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1oex PROBNOT 1 1 NPS NPS 0 0 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 1oez YES 4 2 D2 C2 12754496 0 Paper and SP say dimer -- Annotation transfered from 1hl4 1of0 PROBNOT 1 1 NPS NPS 0 0 Paper says nothing, PISA says monomer -- Annotation transfered from 1hl0 1of3 PROBNOT 2 2 C2 C2 12791255 11282611 Seem to exist in equilibrium between monomers and dimers 1of4 PROBNOT 1 1 NPS NPS 12791255 11282611 Seem to exist in equilibrium between monomers and dimers 1of6_1 YES 2 4 C2 D2 0 15019786 Paper says tetramer - Interface geometry similar to 1qr7 (57%) - automatic transfer from 1oab 1of6_2 YES 2 4 C2 D2 0 15019786 Paper says tetramer - Interface geometry similar to 1qr7 (57%) - automatic transfer from 1oab 1of6_3 YES 2 4 C2 D2 0 15019786 Paper says tetramer - Interface geometry similar to 1qr7 (57%) - automatic transfer from 1oab 1of6_4 YES 2 4 C2 D2 0 15019786 Paper says tetramer - Interface geometry similar to 1qr7 (57%) - automatic transfer from 1oab 1of8 YES 2 4 C2 D2 15019786 0 Paper says tetramer - Interface geometry similar to 1qr7 (57%) -- Annotation transfered from 1oab 1ofa YES 2 4 C2 D2 15019786 0 Paper says tetramer - Interface geometry similar to 1qr7 (57%) -- Annotation transfered from 1oab 1ofb YES 2 4 C2 D2 15019786 0 Paper says tetramer - Interface geometry similar to 1qr7 (57%) -- Annotation transfered from 1oab 1off NO 1 1 NPS NPS 12818206 12818206 The experimental scattering data are presented in Figure 7 and the structural parameters obtained from these data sets are given in Table 2. The estimated molecular mass of the Fd molecule (about 12 kDa) corresponds to the value expected for a monomeric protein (10 kDa), and the experimental radius of gyration Rg is close to that computed from the Synechocystis Fd structure. Moreover, the theoretical scattering pattern computed from the crystallographic model of Synechocystis Fd yields a fair agreement (Figure 7; chi=1.3) with the experimental scattering from the Fd molecule. From this we concluded that Fd is largely monomeric in solution and its overall shape is similar to that of the crystallographic model. 1ofg_1 NO 4 4 D2 D2 8994968 11705375 BU changed since last release and is now corrected - Interface geometry conserved with 1tlt (20%) - automatic transfer from 1h6b 1ofg_2 NO 4 4 D2 D2 8994968 11705375 BU changed since last release and is now corrected - Interface geometry conserved with 1tlt (20%) - automatic transfer from 1h6b 1ofh YES 9 18 NPS C6 12823960 0 BU changed since last release and is now incorrect - -- Annotation transfered from 1ofi 1ofi YES 9 18 NPS C6 12823960 0 BU changed since last release and is now incorrect - 1ofj NO 1 1 NPS NPS 9915818 9915818 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1ofk NO 1 1 NPS NPS 9915818 9915818 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1ofn NO 2 2 C2 C2 12077451 0 Interface geometry conserved with 1rtv (36%) 1ofo YES 2 4 C2 D2 0 0 Paper says tetramer - Interface geometry similar to 1qr7 (57%) -- Annotation transfered from 1oab 1ofp_1 YES 2 4 C2 D2 15019786 15019786 Paper says tetramer - Interface geometry similar to 1qr7 (57%) - automatic transfer from 1oab 1ofp_2 YES 2 4 C2 D2 15019786 0 BU changed since last release and is now incorrect - cf. 1oab - automaticaly inferred from 1hfb 1ofq_1 YES 2 4 C2 D2 15019786 0 BU changed since last release and is now incorrect - cf. 1oab - automaticaly inferred from 1hfb 1ofq_2 YES 2 4 C2 D2 15019786 0 BU changed since last release and is now incorrect - cf. 1oab - automaticaly inferred from 1hfb 1ofr_1 YES 2 4 C2 D2 0 15019786 Paper says tetramer - Interface geometry similar to 1qr7 (57%) - automatic transfer from 1oab 1ofr_2 YES 2 4 C2 D2 0 15019786 Paper says tetramer - Interface geometry similar to 1qr7 (57%) - automatic transfer from 1oab 1ofr_3 YES 2 4 C2 D2 0 15019786 Paper says tetramer - Interface geometry similar to 1qr7 (57%) - automatic transfer from 1oab 1ofr_4 YES 2 4 C2 D2 0 15019786 Paper says tetramer - Interface geometry similar to 1qr7 (57%) - automatic transfer from 1oab 1ofv PROBNOT 1 1 NPS NPS 10610791 0 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1czh 1ofw_1 YES 1 2 NPS C2 12750363 12750363 BU changed since last release and is now incorrect - Interface geometry conserved with 1duw (85% id) 1ofw_2 YES 1 2 NPS C2 12750363 12750363 BU changed since last release and is now incorrect - Interface geometry conserved with 1duw (85% id) 1ofy NO 2 2 C2 C2 12750363 0 Interface geometry conserved with 1duw (85% id) -- Annotation transfered from 1ofw 1og0_1 YES 2 4 C2 D2 0 15019786 Paper says tetramer - Interface geometry similar to 1qr7 (57%) - automatic transfer from 1oab 1og0_2 YES 2 4 C2 D2 0 15019786 Paper says tetramer - Interface geometry similar to 1qr7 (57%) - automatic transfer from 1oab 1og0_3 YES 2 4 C2 D2 0 15019786 Paper says tetramer - Interface geometry similar to 1qr7 (57%) - automatic transfer from 1oab 1og0_4 YES 2 4 C2 D2 0 15019786 Paper says tetramer - Interface geometry similar to 1qr7 (57%) - automatic transfer from 1oab 1og1 PROBNOT 1 1 NPS NPS 12939142 0 -- Annotation transfered from 1gy0 1og2_1 PROBNOT 1 1 NPS NPS 12861225 15181000 BU changed since last release and is now corrected - Paper does not speak about dimer - PISA says monomer and found this http://pubs.acs.org/subscribe/journals/jacsat/suppinfo/ja0608693/ja0608693.pdf where they describe a monomer too 1og2_2 PROBNOT 1 1 NPS NPS 12861225 15181000 BU changed since last release and is now corrected - Paper does not speak about dimer - PISA says monomer and found this http://pubs.acs.org/subscribe/journals/jacsat/suppinfo/ja0608693/ja0608693.pdf where they describe a monomer too 1og3 PROBNOT 1 1 NPS NPS 12939142 0 -- Annotation transfered from 1gy0 1og4 PROBNOT 1 1 NPS NPS 12939142 0 -- Annotation transfered from 1gy0 1og5 PROBYES 2 1 C2 NPS 12861225 0 Paper does not speak about dimer - PISA says monomer and found this http://pubs.acs.org/subscribe/journals/jacsat/suppinfo/ja0608693/ja0608693.pdf where they describe a monomer too -- Annotation transfered from 1og2 1og6 PROBNOT 3 3 C3 C3 0 0 Given the burried ASA I hardly believe the trimer could be an artifact 1ogh YES 2 6 NS D3 0 0 BU changed since last release and is now incorrect - 12909016 says: DCD-DUT is a hexamer 1ogi NO 1 1 NPS NPS 14500716 0 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1ogj NO 1 1 NPS NPS 14500716 0 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1ogr PROBNOT 1 1 NPS NPS 0 0 Paper says nothing, PISA says monomer -- Annotation transfered from 1hl0 1ogw PROBNOT 1 1 NPS NPS 0 0 Ubiquitin binds to proteins in different forms that may lead to the degradation of the target protein. For this reason I will consider all the ubiquitin structures to be correct. i.e. different forms may exist. -- Annotation transfered from 1ubq 1ogx NO 2 2 C2 C2 11007792 0 -- Annotation transfered from 1e3v 1ogz YES 1 2 NPS C2 12852789 0 homologous are dimers and PISA and SP say dimer 1oh0 NO 2 2 C2 C2 9369474 0 -- Annotation transfered from 1e3v 1oh4 PROBNOT 1 1 NPS NPS 12791255 0 Seem to exist as monomers and dimers -- Annotation transfered from 1of4 1ohj PROBNOT 1 1 NPS NPS 9374868 9374868 -- Annotation transfered from 1s3u 1ohk PROBNOT 1 1 NPS NPS 9374868 9374868 -- Annotation transfered from 1s3u 1ohl NO 8 8 D4 D4 12777167 0 Paper says octamer -- Annotation transfered from 1qml 1oho NO 2 2 C2 C2 0 11389596 BU changed since last release and is now corrected - All identical are dimers and PISA says dimer for this one - automatic transfer from 1e97 1ohp_1 PROBNOT 2 2 C2 C2 0 9369474 - automatic transfer from 8cho 1ohp_2 PROBNOT 2 2 C2 C2 0 9369474 - automatic transfer from 8cho 1ohq NO 2 2 C2 C2 15033359 0 1ohr NO 2 2 C2 C2 9397180 9397180 -- Annotation transfered from 1ajx 1ohs_1 PROBNOT 2 2 C2 C2 0 9369474 - automatic transfer from 8cho 1ohs_2 PROBNOT 2 2 C2 C2 0 9369474 - automatic transfer from 8cho 1oi4 NA 2 2 C2 C2 0 0 No paper, but another biochemical paper (16380269) says - protein exists in monomeric, trimeric, and hexameric forms - I find that quite strange but interesting. Plus the related protein 1g2i cannot form trimers. My guess is that this dimer is relevant because the interface geometry is conserved with the one from 1g2i which has less than 50% similarity. 1oi6 NO 2 2 C2 C2 15159413 0 Interface geometry conserved with 1rtv (36%) -- Annotation transfered from 1ofn 1oil_1 PROBNOT 1 1 NPS NPS 9032073 9660188 SP says monomer, PISA too - automatic transfer from 5lip 1oil_2 PROBNOT 1 1 NPS NPS 9032073 9660188 SP says monomer, PISA too - automatic transfer from 5lip 1oio YES 2 1 NS NPS 12909017 12909017 Paper says: The two NCS monomers in the asymmetric unit are not related by a 2-fold rotation and do not form a closed point group. This is consistent with the expected monomeric nature of the fragment, and thus the dimerization is an artifact of crystallization. 1oiq NO 1 1 NPS NPS 12941325 0 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1oir NO 1 1 NPS NPS 12941325 0 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1oit NO 1 1 NPS NPS 12941325 0 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1oiv PROBYES 2 1 C2 NPS 0 14699104 Paper claims dimerization would occur when protein is bound to the membrane and hides the interaction surfaces. But nothing shows it explicitely, plus no dimer was found in solution 1oiw PROBNOT 1 1 NPS NPS 0 0 1oix PROBNOT 1 1 NPS NPS 15837192 14699104 BU changed since last release and is now corrected - Paper claims dimerization would occur when protein is bound to the membrane and hides the interaction surfaces. But nothing shows it explicitely, plus no dimer was found in solution - automaticaly inferred from 1oiv 1oj1 PROBNOT 1 1 NPS NPS 0 0 1oj4 PROBNOT 2 2 C2 C2 12878729 12878729 Despite such a small area of interaction, a dimer is observed in gel filtration experiments and persists even in matrix-assisted laser desorption time-of-flight MS -- PISA error 1oj6_1 NO 1 1 NPS NPS 12962627 12962627 BU changed since last release and is now corrected - In this respect, however, it must be considered that ligand binding studies do not indicate the presence of cooperativity in O2 binding and that size exclusion chromatography does not provide evidence for the presence of a dimeric species in solution. 1oj6_2 NO 1 1 NPS NPS 12962627 12962627 BU changed since last release and is now corrected - In this respect, however, it must be considered that ligand binding studies do not indicate the presence of cooperativity in O2 binding and that size exclusion chromatography does not provide evidence for the presence of a dimeric species in solution. 1oj6_3 NO 1 1 NPS NPS 12962627 12962627 BU changed since last release and is now corrected - In this respect, however, it must be considered that ligand binding studies do not indicate the presence of cooperativity in O2 binding and that size exclusion chromatography does not provide evidence for the presence of a dimeric species in solution. 1oj6_4 NO 1 1 NPS NPS 12962627 12962627 BU changed since last release and is now corrected - In this respect, however, it must be considered that ligand binding studies do not indicate the presence of cooperativity in O2 binding and that size exclusion chromatography does not provide evidence for the presence of a dimeric species in solution. 1oj8 PROBNOT 1 1 NPS NPS 0 0 -- Annotation transfered from 1oj1 1oj9 NO 2 2 C2 C2 12913124 0 Paper says dimer -- Annotation transfered from 1gos 1oja NO 2 2 C2 C2 12913124 0 Paper says dimer -- Annotation transfered from 1gos 1ojb NO 2 2 C2 C2 12913124 0 Paper says dimer -- Annotation transfered from 1gos 1ojc NO 2 2 C2 C2 12913124 0 Paper says dimer -- Annotation transfered from 1gos 1ojd_1 NO 2 2 C2 C2 12913124 11753429 BU changed since last release and is now corrected - 1ojd_2 NO 2 2 C2 C2 12913124 11753429 BU changed since last release and is now corrected - 1ojd_3 NO 2 2 C2 C2 12913124 11753429 BU changed since last release and is now corrected - 1ojd_4 NO 2 2 C2 C2 12913124 11753429 BU changed since last release and is now corrected - 1ojd_5 NO 2 2 C2 C2 12913124 11753429 BU changed since last release and is now corrected - 1oji PROBNOT 1 1 NPS NPS 12890535 0 SP says monomer -- Annotation transfered from 1a39 1ojj PROBYES 2 1 NS NPS 12890535 9335168 BU changed since last release and is now incorrect - SP says monomer - automaticaly inferred from 1a39 1ojk PROBYES 2 1 NS NPS 12890535 9335168 BU changed since last release and is now incorrect - SP says monomer - automaticaly inferred from 1a39 1ojr NO 4 4 C4 C4 12962479 0 BU changed since last release and is now corrected - EcoCyc and paper say tetramer 1ojs NO 2 2 C2 C2 14659762 0 A. fulgidus malate dehydrogenase is the only dimeric protein known to date that belongs to the [LDH-like] MalDH family. All the other known members of this family are homo-tetramers. The crystal structures revealed that the association of the dimers to form tetramers is prevented by several deletions, taking place at the level of two loops that are known to be essential for the tetramerisation process within the LDH and [LDH-like] MalDH enzymes. -- Annotation transfered from 1oju 1ojt NO 2 2 C2 C2 9193005 9193005 Paper says dimer 1oju NO 2 2 C2 C2 14659762 14659762 A. fulgidus malate dehydrogenase is the only dimeric protein known to date that belongs to the [LDH-like] MalDH family. All the other known members of this family are homo-tetramers. The crystal structures revealed that the association of the dimers to form tetramers is prevented by several deletions, taking place at the level of two loops that are known to be essential for the tetramerisation process within the LDH and [LDH-like] MalDH enzymes. 1ok8 YES 1 3 NPS C3 14737159 14737159 BU changed since last release and is now incorrect - Paper says: A three-dimensional structure of the soluble E ectodomain (sE) in its trimeric, postfusion state reveals striking differences from the dimeric, prefusion form. 1oke NO 2 2 C2 C2 12759475 0 14737159 says: A three-dimensional structure of the soluble E ectodomain (sE) in its trimeric, postfusion state reveals striking differences from the dimeric, prefusion form. -- Annotation transfered from 1oan 1okh NA 2 2 C2 C2 14646070 14646070 The questions as to whether the dimer connected by hydrophobic interactions or the tetramer-like associate correspond to the physiological unit and whether they play any role in membrane disruption remain open. There are, however, indications that thionins associate at higher concentrations. 1oki PROBNOT 2 2 C2 C2 14573871 14573871 Interesting: same interaction as in 1bd7 even though 1bd7 has been engineered! and seq identity as low as 50%. 1okl PROBNOT 1 1 NPS NPS 8557623 8557623 9000633 says monomeric -- Annotation transfered from 1uga 1okm PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1okn PROBNOT 1 1 NPS NPS -1 0 9000633 says monomeric -- Annotation transfered from 1uga 1okt PROBNOT 2 2 C2 C2 14623980 0 BU changed since last release and is now corrected - Paper says it is a dimer 1okx PROBYES 2 1 C2 NPS 14583266 9443341 BU changed since last release and is now incorrect - - automaticaly inferred from 1c1m 1oky NO 1 1 NPS NPS 12892559 0 gel filtration studies suggest that PDK1 is monomeric -- Annotation transfered from 1okz 1okz NO 1 1 NPS NPS 12892559 15209375 gel filtration studies suggest that PDK1 is monomeric 1ol6 PROBNOT 1 1 NPS NPS 14580337 0 Paper does not mention oligomer - PISA says monomer -- Annotation transfered from 1mq4 1ol7 PROBNOT 1 1 NPS NPS 14580337 0 Paper does not mention oligomer - PISA says monomer -- Annotation transfered from 1mq4 1olo NO 6 6 C6 C6 14530440 0 BU changed since last release and is now corrected - 1olp PROBYES 4 1 NS NPS 14568535 0 Paper says: This crystallographic dimer is clearly not biologically relevant as the active sites are occluded in both molecules. 1olq PROBYES 2 1 C2 NPS 14627738 11327768 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - In dynamic light-scattering analysis the protein appears only as a monomer - automaticaly inferred from 1h8v_2 1olr PROBNOT 1 1 NPS NPS 14627738 0 Paper says nothing, PISA says monomer -- Annotation transfered from 1uu4 1om1 NO 1 1 NPS NPS 12816539 12816539 Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. -- Annotation transfered from 1jam 1om4 NO 2 2 C2 C2 0 0 Clear dimer -- Annotation transfered from 1m00 1om5 NO 2 2 C2 C2 0 0 Clear dimer -- Annotation transfered from 1m00 1om9_1 PROBNOT 1 1 NPS NPS 12858163 12808037 BU changed since last release and is now corrected - Fragment (150 aa of >600). SP says monomeric - paper says: we do not see any evidence for dimerization in solution by using either gel filtration or dynamic light scattering, suggesting that this is not an in vivo natural dimeric interaction. - automaticaly inferred from 1na8 1om9_2 PROBNOT 1 1 NPS NPS 12858163 12808037 BU changed since last release and is now corrected - Fragment (150 aa of >600). SP says monomeric - paper says: we do not see any evidence for dimerization in solution by using either gel filtration or dynamic light scattering, suggesting that this is not an in vivo natural dimeric interaction. - automaticaly inferred from 1na8 1omd PROBNOT 1 1 NPS NPS 2231727 2231727 Similar structures are either monomers or weak dimers - Paper does not mention dimer - PISA says monomer 1ome PROBYES 2 1 NS NPS 9521648 9521648 Class A betalactamase are apparently monomeric in solution (said in paper) 1omp PROBNOT 1 1 NPS NPS 1420181 1420181 EcoCyc says monomer -- Annotation transfered from 1nl5 1omr PROBNOT 1 1 NPS NPS 12686556 1358206 The elution volume of recoverin corresponds to a monomer. 1oms PROBYES 3 2 NS C2 14656439 0 Annotated during the 3D Complex curation 1omv PROBNOT 1 1 NPS NPS 12686556 12686556 The elution volume of recoverin corresponds to a monomer. -- Annotation transfered from 1omr 1omy PROBNOT 1 1 NPS NPS 12925796 12925796 Paper says nothing, related structures are monomeric and PISA says monomer 1on0 PROBYES 4 2 NS C2 0 0 14635137 says: The gel filtration experiment indicated the oligomeric form to be a dimer (data not shown). A structural homologue of YYCN, yeast Hpa2, has been shown to be present as a dimer in solution but forms a stable tetramer in the presence of its cofactor, acetyl CoA. 1on1 NO 2 2 C2 C2 12847518 12847518 Interface geometry conserved down to 30% with 1b1b 1on2 NO 2 2 C2 C2 12847518 12847518 Interface geometry conserved down to 30% with 1b1b -- Annotation transfered from 1on1 1on3 NO 6 6 D3 D3 12743028 12743028 Paper says hexamer: Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme core 1on9 NO 6 6 D3 D3 12743028 12743028 Paper says hexamer: Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme core -- Annotation transfered from 1on3 1ona NO 4 4 D2 D2 8940035 8940035 SP says tetramer -- Annotation transfered from 1cjp 1onc PROBNOT 1 1 NPS NPS 8120892 8120892 1one NO 2 2 C2 C2 8605183 8605183 Interface conserved with 1te6 (62% id) 1onf NO 2 2 C2 C2 12729762 12729762 SP says homodimer 1ong PROBNOT 1 1 NPS NPS 14609325 14609325 1onh PROBNOT 1 1 NPS NPS 14609325 14609325 This is a class C beta Lactamase and those are monomeric (12951239) -- Annotation transfered from 1c3b -- Annotation transfered from 1ga0 1oni_1 NO 3 3 C3 C3 14997576 14997576 Interface conserved with 1jd1 (41% seq id) 1oni_2 NO 3 3 C3 C3 14997576 14997576 Interface conserved with 1jd1 (41% seq id) -- Annotation transfered from 1oni_1 1oni_3 NO 3 3 C3 C3 14997576 14997576 Interface conserved with 1jd1 (41% seq id) -- Annotation transfered from 1oni_1 1onj NA 1 1 NPS NPS 12777767 12777767 Ask the persons who work with it 1ons NO 2 2 C2 C2 14500888 14500888 It is a homodimer but it is strange to see that the dimerization mode seems different from the one in 1izy (different surface but similar orientation). Interesting to investigate 1onw NO 8 8 D4 D4 12718528 12718528 Paper says: The quaternary structure of the enzyme is octameric and can be aptly described as a tetramer of dimers. 1onx NO 8 8 D4 D4 12718528 12718528 Paper says: The quaternary structure of the enzyme is octameric and can be aptly described as a tetramer of dimers. -- Annotation transfered from 1onw 1ony PROBNOT 1 1 NPS NPS 12747781 12747781 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1onz PROBNOT 1 1 NPS NPS 12747781 12747781 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1oo2 NO 4 4 D2 D2 14644428 14644428 Paper says tetramer -- Annotation transfered from 1sn0 1oo8 PROBNOT 1 1 NPS NPS 12860985 12860985 Paper says nothing, forms a heterodimer with an apparent 1:1 ratio (1oph) and PISA says monomer 1ooj PROBNOT 1 1 NPS NPS 14635136 14635136 -- Annotation transfered from 3cln 1oot PROBNOT 1 1 NPS NPS 0 0 No paper, related structures are monomers and PISA says monomer 1oow PROBNOT 1 1 NPS NPS 14670610 14670610 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) 1ooy NO 4 4 D2 D2 15388917 15388917 Pig heart SCOT can exist as both a dimer and a tetramer (Rochet et al., 2000) 1ooz YES 4 2 C2 C2 15388917 15388917 Pig heart SCOT can exist as both a dimer and a tetramer (Rochet et al., 2000), but the interpretation was that the initial crystal structure solved shows the dimer (Bateman et al., 2002). The two monomers in the pig heart SCOT dimer interact in the same way that two ab-heterodimers interact in the GCT structure (Bateman et al., 2002). 1op0 PROBNOT 1 1 NPS NPS 15632114 15632114 Paper says nothing, PISA says monomer and related structures are mostly monomeric 1op2 PROBNOT 1 1 NPS NPS 15632114 15632114 Paper says nothing, PISA says monomer and related structures are mostly monomeric -- Annotation transfered from 1op0 1op8_1 NO 2 2 C2 C2 12819770 12819769 Very interesting - the dimeric form contributes to substrate specificity. - automatic transfer from 1orf 1op8_2 NO 2 2 C2 C2 12819770 12819769 Very interesting - the dimeric form contributes to substrate specificity. - automatic transfer from 1orf 1op8_3 NO 2 2 C2 C2 12819770 12819769 Very interesting - the dimeric form contributes to substrate specificity. - automatic transfer from 1orf 1opa PROBYES 2 1 C2 NPS 8487303 8487303 PISA says monomer, SP too, and I would say the same after looking at the structure. 1opb_1 PROBNOT 1 1 NPS NPS 8487303 8487303 BU changed since last release and is now corrected - PISA says monomer, SP too, and I would say the same after looking at the structure. - automaticaly inferred from 1opa 1opb_2 PROBNOT 1 1 NPS NPS 8487303 8487303 BU changed since last release and is now corrected - PISA says monomer, SP too, and I would say the same after looking at the structure. - automaticaly inferred from 1opa 1opb_3 PROBNOT 1 1 NPS NPS 8487303 8487303 BU changed since last release and is now corrected - PISA says monomer, SP too, and I would say the same after looking at the structure. - automaticaly inferred from 1opa 1opb_4 PROBNOT 1 1 NPS NPS 8487303 8487303 BU changed since last release and is now corrected - PISA says monomer, SP too, and I would say the same after looking at the structure. - automaticaly inferred from 1opa 1opd NO 1 1 NPS NPS 8784179 9334229 E. coli HPr is a small, monomeric protein 1ope NO 4 4 D2 D2 15388917 15388917 Pig heart SCOT can exist as both a dimer and a tetramer (Rochet et al., 2000) -- Annotation transfered from 1ooy 1opf_1 NO 3 3 C3 C3 8589999 8702816 Interface geometry conserved with 1prn (20%) - automatic transfer from 1gfn 1opf_2 NO 3 3 C3 C3 8589999 8702816 Interface geometry conserved with 1prn (20%) - automatic transfer from 1gfn 1opk PROBNOT 1 1 NPS NPS 12654251 12654251 Dimer not mentioned in the paper - PISA says dimer? 1opl_1 PROBNOT 1 1 NPS NPS 12654251 12654251 Dimer not mentioned in the paper - PISA says dimer? - automatic transfer from 1opk 1opx NO 6 6 C6 C6 12727865 12727865 PAper says hexamer -- Annotation transfered from 1nlz 1opy NO 2 2 C2 C2 9103200 9103200 -- Annotation transfered from 1e3v 1oq5 PROBNOT 1 1 NPS NPS 14736236 14736236 9000633 says monomeric -- Annotation transfered from 1uga 1oqf NO 4 4 D2 D2 15723538 15723538 Interface geometry conserved with 1pym (30%) 1oqz YES 2 2 NS C2 12680762 12680762 Paper shows a symmetric dimer -- PISA finds it 1or8 YES 1 2 NPS C2 12737817 12737817 Paper says dimer -- Annotation transfered from 1ori 1orc NO 1 1 NPS NPS 8547253 8547253 Engineered monomer 1ord NO 2 2 C2 C2 7563080 7563080 1orf NO 2 2 C2 C2 12819769 12819769 Very interesting - the dimeric form contributes to substrate specificity. 1orh YES 1 2 NPS C2 12737817 12737817 Paper says dimer -- Annotation transfered from 1ori 1ori YES 1 2 NPS C2 12737817 12737817 Paper says dimer 1orn PROBNOT 1 1 NPS NPS 12840008 12840008 1orp PROBNOT 1 1 NPS NPS 12840008 12840008 -- Annotation transfered from 1orn 1orr NO 4 4 D2 D2 12642575 12642575 Paper says tetramer 1ort NO 12 12 Tetr Tetr 7479879 7479879 Interface geometry conserved with 1vlv (44%) 1orv NO 4 4 D2 D2 12690074 12690074 The tetramer encloses a large cavity and may explain why the high molecular weight form of DP IV behaves as a hexamer on gel filtration chromatography -- very interesting case: exists in two forms, one membranne bound and one soluble. May mediate cell-cell interactions (two mem. bound) or, the soluble could interfere and disrupt the cell-cell interaction - there is a glycosilation important for tetramerization regulation - active site not at the interface. Very complete example for a talk or for teaching or for a paper 1orw NO 4 4 D2 D2 12690074 12690074 The tetramer encloses a large cavity and may explain why the high molecular weight form of DP IV behaves as a hexamer on gel filtration chromatography -- very interesting case: exists in two forms, one membranne bound and one soluble. May mediate cell-cell interactions (two mem. bound) or, the soluble could interfere and disrupt the cell-cell interaction - there is a glycosilation important for tetramerization regulation - active site not at the interface. Very complete example for a talk or for teaching or for a paper -- Annotation transfered from 1orv 1os0 PROBNOT 1 1 NPS NPS 12832763 8639498 thermolysin fragment corresponds to a mixture of monomers and dimers 1os1 NO 1 1 NPS NPS 12837799 12837799 Paper says: E. coli PCK is a monomeric, globular protein 1os5 NO 1 1 NPS NPS 12805457 12805457 HCV RdRp exists primarily as a monomer -- Annotation transfered from 1gx6 1os6 NA 1 1 NPS NPS 14744127 14744127 Paper mentions gel filtration but no dimer - PISA says dimer but family mostly monomeric 1os8 PROBNOT 1 1 NPS NPS 12885239 12885239 Paper says nothing, related structures are monomeric and PISA says monomer 1osa NO 1 1 NPS NPS 15299476 0 -- Annotation transfered from 1exr 1osf NA 1 1 NPS NPS 12725864 12725864 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization -- Annotation transfered from 1uy6 1osg_1 YES 3 60 C3 Icos 12755599 11853672 BU changed since last release and is now incorrect - The virus-like assembly was also detected in solution using gel filtration and electron microscopy. -- very nice example of C3 --> Icosah - automaticaly inferred from 1jh5 1osg_2 YES 3 60 C3 Icos 12755599 11853672 BU changed since last release and is now incorrect - The virus-like assembly was also detected in solution using gel filtration and electron microscopy. -- very nice example of C3 --> Icosah - automaticaly inferred from 1jh5 1osh PROBNOT 1 1 NPS NPS 12718892 12718892 Paper says it forms a heterodimer with RXR. 1osm NO 3 3 C3 C3 10196126 10196126 Interface geometry conserved with 1prn (28%) 1oss PROBNOT 1 1 NPS NPS 12885239 12885239 Paper says nothing, related structures are monomeric and PISA says monomer -- Annotation transfered from 1os8 1ot1 NO 1 1 NPS NPS 12706817 12706817 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1ot2 NO 1 1 NPS NPS 12706817 12706817 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1ot5_1 NA 1 1 NPS NPS 12779325 17426142 Papers do not give information and PISA suggests a dimer. -- Annotation transfered from 2id4_2 1ot5_2 NA 1 1 NPS NPS 12779325 17426142 Papers do not give information and PISA suggests a dimer. -- Annotation transfered from 2id4_2 1ot6 YES 2 1 NS NPS 15159559 15159559 Sp says monomer -- Annotation transfered from 1ot9 1ot9 YES 2 1 NS NPS 15159559 15159559 Sp says monomer 1ota PROBNOT 1 1 NPS NPS 15159559 15159559 SP says monomer -- Annotation transfered from 1s1z 1otb PROBNOT 1 1 NPS NPS 15159559 15159559 SP says monomer -- Annotation transfered from 1s1z 1ote PROBNOT 1 1 NPS NPS 15159559 15159559 SP says monomer -- Annotation transfered from 1s1z 1otf NO 6 6 D3 D3 8547259 8547259 interface conserved with 1mww (21%) -- SCOP dom_arch error 1oth NO 3 3 C3 C3 9852088 9852088 Paper says trimer 1oti PROBNOT 1 1 NPS NPS 15159559 15159559 SP says monomer -- Annotation transfered from 1s1z 1otx NO 6 6 D3 D3 14700625 14700625 Paper and SP say hexamer -- Annotation transfered from 1ovg 1oty NO 6 6 D3 D3 14700625 14700625 Paper and SP say hexamer -- Annotation transfered from 1ovg 1ou0 NA 4 2 D2 C2 15609338 15609338 Paper says: The CobH active site is formed by the dimer interface, and the activity of the dimer in solution has been demonstrated - could be a dimer and not a tetramer? 1ou4 NO 6 6 D3 D3 14700625 14700625 Paper and SP say hexamer -- Annotation transfered from 1ovg 1ou6 NO 4 4 D2 D2 0 0 Paper says tetramer -- Annotation transfered from 1dm3 1oua NO 1 1 NPS NPS 9010773 9010773 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1oub NO 1 1 NPS NPS 9020766 9020766 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ouc NO 1 1 NPS NPS 9020766 0 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1oud NO 1 1 NPS NPS 9010773 9010773 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1oue NO 1 1 NPS NPS 9010773 9010773 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ouf NO 1 1 NPS NPS 9010773 9010773 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1oug NO 1 1 NPS NPS 9010773 9010773 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ouh NO 1 1 NPS NPS 9010773 9010773 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1oui NO 1 1 NPS NPS 9010773 9010773 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ouj NO 1 1 NPS NPS 9010773 9010773 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1ouk PROBNOT 1 1 NPS NPS 12897767 12897767 -- Annotation transfered from 1kv1 1oum NO 6 6 D3 D3 14700625 14700625 Paper and SP say hexamer -- Annotation transfered from 1ovg 1oun NO 2 2 C2 C2 8757804 8757804 NTF2 eluted with an apparent Mr of 31 kDa consistent with its existing in solution as dimers. 1ouq NO 4 4 C4 C4 12954782 12954782 BU changed since last release and is now corrected - Paper says tetramer 1ouy PROBNOT 1 1 NPS NPS 12897767 12897767 -- Annotation transfered from 1kv1 1ov3 NO 2 2 C2 C2 12732142 12732142 Swapped dimer 1ov4 NO 2 2 C2 C2 14573603 14573603 the active protein is a homodimer in solution and this interface is conserved among other distant proteins so it is surely right. 1ov5 NO 1 1 NPS NPS 15046985 15046985 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1ov6 NO 6 6 D3 D3 14700625 14700625 Paper and SP say hexamer -- Annotation transfered from 1ovg 1ov7 NO 1 1 NPS NPS 15046985 15046985 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1ov8_1 PROBNOT 1 1 NPS NPS 12925783 11178893 Paper says nothing - PISA says monomer - automatic transfer from 1qhq 1ov8_2 PROBNOT 1 1 NPS NPS 12925783 11178893 Paper says nothing - PISA says monomer - automatic transfer from 1qhq 1ov8_3 PROBNOT 1 1 NPS NPS 12925783 11178893 Paper says nothing - PISA says monomer - automatic transfer from 1qhq 1ov8_4 PROBNOT 1 1 NPS NPS 12925783 11178893 Paper says nothing - PISA says monomer - automatic transfer from 1qhq 1ovd NO 2 2 C2 C2 12732650 12732650 -- Annotation transfered from 1jub 1ove PROBNOT 1 1 NPS NPS 12897767 12897767 -- Annotation transfered from 1kv1 1ovg NO 6 6 D3 D3 14700625 14700625 Paper and SP say hexamer 1ovh NO 1 1 NPS NPS 15046985 15046985 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1ovj NO 1 1 NPS NPS 15046985 15046985 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1ovk NO 1 1 NPS NPS 15046985 15046985 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1ovm NO 4 4 D2 D2 12752451 12752451 Interface geometry conserved with 1zpd (31%) 1ovr PROBYES 4 2 NS C2 0 0 BU changed since last release and is now incorrect - Four helix bundle -- Check symmetry search -- Annotation transfered from 1ovu 1ovu PROBYES 4 2 NS C2 12876346 0 BU changed since last release and is now incorrect - Four helix bundle -- Check symmetry search 1ovv PROBYES 6 2 NS C2 12876346 12876346 Four helix bundle 1ow2 PROBYES 2 1 C2 NPS 14696183 14696183 Seems to be a monomer - PISA would be wrong -- Annotation transfered from 1nfs 1ow6 YES 4 2 NS C2 14527389 14527389 Domain swapped dimer found here 1ow7 YES 3 1 NS NPS 14527389 14527389 Paper says that if not domain swapped the protein is monomeric -- Annotation transfered from 1ow8 1ow8 YES 3 1 NS NPS 14527389 14527389 Paper says that if not domain swapped the protein is monomeric 1owb NO 6 6 D3 D3 12824188 12824188 Paper says hexamer -- Annotation transfered from 1nxg 1owc NO 6 6 D3 D3 12824188 12824188 Paper says hexamer -- Annotation transfered from 1nxg 1owd PROBNOT 1 1 NPS NPS 14711304 14711304 1owe PROBNOT 1 1 NPS NPS 14711304 14711304 -- Annotation transfered from 1owd 1owh PROBNOT 1 1 NPS NPS 14711304 14711304 -- Annotation transfered from 1owd 1owi PROBNOT 1 1 NPS NPS 14711304 14711304 -- Annotation transfered from 1owd 1owj PROBNOT 1 1 NPS NPS 14711304 14711304 -- Annotation transfered from 1owd 1owk PROBNOT 1 1 NPS NPS 14711304 14711304 -- Annotation transfered from 1owd 1owq NO 1 1 NPS NPS 0 0 Elutes as a monomer - Papers says: The second peak in this final chromatographic step corresponded to a molecular mass of 40 kDa. -- Annotation transfered from 1ljy 1owy NO 1 1 NPS NPS 15046985 15046985 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1owz NO 1 1 NPS NPS 15046985 15046985 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1ox1 PROBNOT 1 1 NPS NPS 0 0 -- Annotation transfered from 1az8 1oxa PROBNOT 1 1 NPS NPS 7749919 7749919 Paper does not mention oligomer - PISA says monomer - many instances of monomers -- Annotation transfered from 1egy 1oxb PROBNOT 2 2 NPS NPS 14656441 14656441 Same structure as that described in the paper 1oxd NO 1 1 NPS NPS 12729742 12729742 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1oxe NO 1 1 NPS NPS 12729742 12729742 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium 1oxf NO 1 1 NPS NPS 12729742 12729742 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1oxg NA 1 1 NPS NPS 15654893 3980476 They explain in the paper (3980476) that chymotrypsin can form an asymetric dimer, but can also be found as a monomer in particular conditions. Here PISA says monomer. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 1ex3 1oxk_1 PROBNOT 2 2 NPS NPS 14656441 14656441 Same structure as that described in the paper -- Annotation transfered from 1oxb 1oxk_2 PROBNOT 2 2 NPS NPS 14656441 14656441 Same structure as that described in the paper -- Annotation transfered from 1oxb 1oxk_3 PROBNOT 2 2 NPS NPS 14656441 14656441 Same structure as that described in the paper -- Annotation transfered from 1oxb 1oxk_4 PROBNOT 2 2 NPS NPS 14656441 14656441 Same structure as that described in the paper -- Annotation transfered from 1oxb 1oxk_5 PROBNOT 2 2 NPS NPS 14656441 14656441 Same structure as that described in the paper -- Annotation transfered from 1oxb 1oxk_6 PROBNOT 2 2 NPS NPS 14656441 14656441 Same structure as that described in the paper -- Annotation transfered from 1oxb 1oxl PROBYES 2 1 NS NPS 16122995 0 SP says monomer 1oxo NO 2 2 C2 C2 8665890 8665890 Interface geometry conserved with 2ay6 (38%) -- Annotation transfered from 1ivr 1oxp NO 2 2 C2 C2 8665890 8665890 Interface geometry conserved with 2ay6 (38%) -- Annotation transfered from 1ivr 1oxr PROBNOT 1 1 NPS NPS 15823962 15823962 Paper says nothing about oligomer - PISA says monomer -- Annotation transfered from 1td7 1oxy PROBYES 1 6 NPS D3 7984626 7984626 Paper says hexamer -- PISA doesnt find it -- Annotation transfered from 1lla 1oy0 NO 10 10 D5 D5 12842039 12842039 Interface geometry conserved with 1o66 - domain swapped dimers 1oya PROBNOT 2 2 C2 C2 7881908 7881908 SP says homodimer -- Annotation transfered from 1oyc 1oyb PROBNOT 2 2 C2 C2 7881908 7881908 SP says homodimer -- Annotation transfered from 1oyc 1oyc PROBNOT 2 2 C2 C2 7881908 7881908 SP says homodimer 1oyh_1 PROBYES 1 2 NPS C2 14623882 15342247 BU changed since last release and is now incorrect - 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization - automaticaly inferred from 1jvq 1oyh_2 PROBYES 1 2 NPS C2 14623882 15342247 BU changed since last release and is now incorrect - 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization - automaticaly inferred from 1jvq 1oyn PROBNOT 4 4 D2 D2 12842049 12842049 the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state 1oyo PROBNOT 1 1 NPS NPS 0 0 -- Annotation transfered from 1p7v 1oyp NO 6 6 D3 D3 14767080 14767080 Wild-type and triple mutant RNase PH crystallize as a hexamer and dimer, respectively. 1oyq PROBNOT 1 1 NPS NPS 11342132 11342132 -- Annotation transfered from 1az8 1oyr NO 6 6 D3 D3 14767080 14767080 Wild-type and triple mutant RNase PH crystallize as a hexamer and dimer, respectively. -- Annotation transfered from 1oyp 1oys NO 2 2 C2 C2 14767080 14767080 Wild-type and triple mutant RNase PH crystallize as a hexamer and dimer, respectively. 1oz1 PROBNOT 1 1 NPS NPS 14561090 14561090 -- Annotation transfered from 1kv1 1oz6 NA 1 1 NPS NPS 14684894 14659748 Paper not accessible at the moment 1oza PROBYES 1 2 NPS C2 15272161 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1q2x 1ozf NO 4 4 D2 D2 14557277 14557277 Interface geometry conserved with 1ovm (22%) -- Annotation transfered from 1ozg 1ozg NO 4 4 D2 D2 14557277 14557277 Interface geometry conserved with 1ovm (22%) 1ozh NO 4 4 D2 D2 14557277 14557277 Interface geometry conserved with 1ovm (22%) -- Annotation transfered from 1ozg 1ozt_1 PROBNOT 2 2 C2 C2 12754496 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1ozt_2 PROBNOT 2 2 C2 C2 12754496 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1ozt_3 PROBNOT 2 2 C2 C2 12754496 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1ozt_4 PROBNOT 2 2 C2 C2 12754496 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1ozu NO 2 2 C2 C2 12754496 12754496 Mammalian Cu,Zn SOD assembles into an unusually stable homodimer with exquisite substrate specificity. Interface conserved down to 50% (at least with 1jcv) -- Annotation transfered from 1n19 1p01 NO 1 1 NPS NPS 3122831 3122831 9846867 says monomer -- Annotation transfered from 1p05 1p02 NO 1 1 NPS NPS 2611204 2611204 9846867 says monomer -- Annotation transfered from 1p05 1p03 NO 1 1 NPS NPS 2611204 2611204 9846867 says monomer -- Annotation transfered from 1p05 1p04 NO 1 1 NPS NPS 2611204 2611204 9846867 says monomer -- Annotation transfered from 1p05 1p05 NO 1 1 NPS NPS 2611204 2611204 9846867 says monomer 1p06 NO 1 1 NPS NPS 2611204 2611204 9846867 says monomer -- Annotation transfered from 1p05 1p09 NO 1 1 NPS NPS 2716847 2716847 9846867 says monomer -- Annotation transfered from 1p05 1p0c NO 2 2 C2 C2 12818203 12818203 1p0f NO 2 2 C2 C2 12818203 12818203 -- Annotation transfered from 1p0c 1p0i NO 1 1 NPS NPS 12869558 12869558 As expected (24 –28), the overall structure of BChE is very similar to that of TcAChE. However, BChE does not form the dimer observed in previous structures of TcAChE (5, 29), mouse AChE (30, 31), and human AChE (32). -- Annotation transfered from 1p0m 1p0m NO 1 1 NPS NPS 12869558 12869558 As expected (24 –28), the overall structure of BChE is very similar to that of TcAChE. However, BChE does not form the dimer observed in previous structures of TcAChE (5, 29), mouse AChE (30, 31), and human AChE (32). 1p0p NO 1 1 NPS NPS 12869558 12869558 As expected (24 –28), the overall structure of BChE is very similar to that of TcAChE. However, BChE does not form the dimer observed in previous structures of TcAChE (5, 29), mouse AChE (30, 31), and human AChE (32). -- Annotation transfered from 1p0m 1p0q NO 1 1 NPS NPS 12869558 12869558 As expected (24 –28), the overall structure of BChE is very similar to that of TcAChE. However, BChE does not form the dimer observed in previous structures of TcAChE (5, 29), mouse AChE (30, 31), and human AChE (32). -- Annotation transfered from 1p0m 1p0v NA 2 1 C2 NPS 14653735 14653735 Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. -- Annotation transfered from 1jme 1p0w NA 2 1 C2 NPS 14653735 14653735 Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. -- Annotation transfered from 1jme 1p0x NA 2 1 C2 NPS 14653735 14653735 Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. -- Annotation transfered from 1jme 1p10 NO 1 1 NPS NPS 2716847 2716847 9846867 says monomer -- Annotation transfered from 1p05 1p11 NO 1 1 NPS NPS 1998685 1998685 9846867 says monomer -- Annotation transfered from 1p05 1p12 NO 1 1 NPS NPS 1998685 1998685 9846867 says monomer -- Annotation transfered from 1p05 1p13_1 PROBNOT 1 1 NPS NPS 12834342 6254988 BU changed since last release and is now corrected - In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution - automaticaly inferred from 1a07 1p13_2 PROBNOT 1 1 NPS NPS 12834342 6254988 BU changed since last release and is now corrected - In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution - automaticaly inferred from 1a07 1p14 PROBNOT 1 1 NPS NPS 12707268 12707268 -- Annotation transfered from 1gag 1p17_1 NO 2 2 C2 C2 14698288 14698288 PID 12070315: Of the 6-oxopurine PRTase structures currently in the literature, four are tetramers (human HGPRT, T. gondii HGXPRT, E. coli XGPRT, and P. falciparum HGXPRT) and three are dimers (G. lamblia GPRT, T. foetus HGXPRT, and T. cruzi HGPRT). - automatic transfer from 1p18 1p17_2 NO 2 2 C2 C2 14698288 14698288 PID 12070315: Of the 6-oxopurine PRTase structures currently in the literature, four are tetramers (human HGPRT, T. gondii HGXPRT, E. coli XGPRT, and P. falciparum HGXPRT) and three are dimers (G. lamblia GPRT, T. foetus HGXPRT, and T. cruzi HGPRT). - automatic transfer from 1p18 1p18 NO 2 2 C2 C2 14698288 14698288 PID 12070315: Of the 6-oxopurine PRTase structures currently in the literature, four are tetramers (human HGPRT, T. gondii HGXPRT, E. coli XGPRT, and P. falciparum HGXPRT) and three are dimers (G. lamblia GPRT, T. foetus HGXPRT, and T. cruzi HGPRT). 1p19_1 NO 2 2 C2 C2 14698288 14698288 PID 12070315: Of the 6-oxopurine PRTase structures currently in the literature, four are tetramers (human HGPRT, T. gondii HGXPRT, E. coli XGPRT, and P. falciparum HGXPRT) and three are dimers (G. lamblia GPRT, T. foetus HGXPRT, and T. cruzi HGPRT). - automatic transfer from 1p18 1p19_2 NO 2 2 C2 C2 14698288 14698288 PID 12070315: Of the 6-oxopurine PRTase structures currently in the literature, four are tetramers (human HGPRT, T. gondii HGXPRT, E. coli XGPRT, and P. falciparum HGXPRT) and three are dimers (G. lamblia GPRT, T. foetus HGXPRT, and T. cruzi HGPRT). - automatic transfer from 1p18 1p1f YES 4 4 C2 D2 12832758 12832758 1p1h NO 4 4 D2 D2 12832758 12832758 MIP synthase is a homotetramer both in solution and in the solid state -- Annotation transfered from 1jki 1p1i NO 4 4 D2 D2 12832758 12832758 MIP synthase is a homotetramer both in solution and in the solid state -- Annotation transfered from 1jki 1p1j NO 4 4 D2 D2 12832758 12832758 MIP synthase is a homotetramer both in solution and in the solid state -- Annotation transfered from 1jki 1p1k NO 4 4 D2 D2 12832758 12832758 MIP synthase is a homotetramer both in solution and in the solid state -- Annotation transfered from 1jki 1p1l PROBYES 1 3 NPS C3 0 0 1p1n NO 2 2 C2 C2 12730367 12730367 Paper says this dimer is real -- Annotation transfered from 1mqi 1p1o NO 2 2 C2 C2 12730367 12730367 Paper says this dimer is real -- Annotation transfered from 1mqi 1p1q_1 PROBNOT 2 2 C2 C2 12730367 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1p1q_2 PROBNOT 2 2 C2 C2 12730367 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1p1r_1 PROBNOT 2 2 C2 C2 12855684 9132002 BU changed since last release and is now corrected - - automaticaly inferred from 1lde 1p1r_2 PROBNOT 2 2 C2 C2 12855684 9132002 BU changed since last release and is now corrected - - automaticaly inferred from 1lde 1p1u NO 2 2 C2 C2 12730367 12730367 Paper says this dimer is real -- Annotation transfered from 1mqi 1p1v_1 PROBNOT 2 2 C2 C2 12649272 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1p1v_2 PROBNOT 2 2 C2 C2 12649272 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1p1w NO 2 2 C2 C2 12730367 12730367 Paper says this dimer is real -- Annotation transfered from 1mqi 1p1x_1 PROBYES 1 2 NPS C2 15476818 0 BU changed since last release and is now incorrect - Interface geometry somewhat conserved with 1mzh (32%) -- interesting: first case that I see where the place of the interaction is conserved but interface has completely changed - automaticaly inferred from 1ktn 1p1x_2 PROBYES 1 2 NPS C2 15476818 0 BU changed since last release and is now incorrect - Interface geometry somewhat conserved with 1mzh (32%) -- interesting: first case that I see where the place of the interaction is conserved but interface has completely changed - automaticaly inferred from 1ktn 1p29 NO 2 2 C2 C2 12930991 12930991 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1p2a NO 1 1 NPS NPS 12852944 12852944 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1p2b NO 2 2 C2 C2 12930991 12930991 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1p2d NO 2 2 C2 C2 12930991 12930991 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1p2e PROBNOT 1 1 NPS NPS 14609326 14609326 SP says monomer -- Annotation transfered from 1qjd 1p2g NO 2 2 C2 C2 12930991 12930991 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1p2h PROBNOT 1 1 NPS NPS 14609326 14609326 SP says monomer -- Annotation transfered from 1qjd 1p2l NO 1 1 NPS NPS 12963380 12963380 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1p2p PROBNOT 2 2 C2 C2 6876174 6876174 Papers of identical structures speak about the dimer as something relevant but it is interesting to note that two modes of dimerization exist among these proteins. I have not seen this discussed -- Annotation transfered from 1fx9 1p2r NO 1 1 NPS NPS 12963380 12963380 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1p2s NO 1 1 NPS NPS 12842038 12842038 Ras proteins are monomeric G proteins -- Annotation transfered from 1ctq 1p2t NO 1 1 NPS NPS 12842038 12842038 Ras proteins are monomeric G proteins -- Annotation transfered from 1ctq 1p2u NO 1 1 NPS NPS 12842038 12842038 Ras proteins are monomeric G proteins -- Annotation transfered from 1ctq 1p2v NO 1 1 NPS NPS 12842038 12842038 Ras proteins are monomeric G proteins -- Annotation transfered from 1ctq 1p2y PROBNOT 1 1 NPS NPS 14556625 14556625 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1p33 NO 4 4 D2 D2 12925782 12925782 paper says tetramer 1p36 NO 1 1 NPS NPS 12963380 12963380 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1p37 NO 1 1 NPS NPS 12963380 12963380 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1p38 PROBNOT 1 1 NPS NPS 9122194 9122194 -- Annotation transfered from 1kv1 1p39 YES 2 1 C2 NPS 9145102 9145102 SP and PISA say monomer -- Annotation transfered from 3mct 1p3j PROBNOT 1 1 NPS NPS 15100224 15100224 SP says monomer 1p3n NO 1 1 NPS NPS 12963380 12963380 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1p3w NO 2 2 C2 C2 12860127 12860127 1p3y NO 12 12 Tetr Tetr 12876343 12876343 Interface geometry conserved with 1g63 (30%) 1p43 NO 2 2 C2 C2 12846578 8605183 Interface conserved with 1te6 (62% id) -- Annotation transfered from 1one 1p44_1 PROBNOT 4 4 D2 D2 12606558 7886450 BU changed since last release and is now corrected - - automaticaly inferred from 1eny 1p44_2 PROBNOT 4 4 D2 D2 12606558 7886450 BU changed since last release and is now corrected - - automaticaly inferred from 1eny 1p45 PROBNOT 4 4 D2 D2 12606558 7886450 BU changed since last release and is now corrected - - automaticaly inferred from 1eny 1p46 NO 1 1 NPS NPS 12963380 12963380 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1p48 NO 2 2 C2 C2 12846578 8605183 Interface conserved with 1te6 (62% id) -- Annotation transfered from 1one 1p49 PROBNOT 1 1 NPS NPS 12657638 12657638 Not said explicitely that it is a monomer though 1p4e NO 4 4 C4 C4 12716882 12559911 Paper says that it s a tetramer. -- Annotation transfered from 1m6x 1p4f PROBNOT 1 1 NPS NPS 14505650 14505650 Paper does not mention oligomer and PISa says monomer 1p4g NO 2 2 C2 C2 -1 0 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1p4h NO 2 2 C2 C2 -1 0 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1p4j NO 2 2 C2 C2 -1 0 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1p4o_1 PROBNOT 1 1 NPS NPS 14501110 11694888 Fragment - Paper says: The IGF1 receptor is structurally homologous to the insulin receptor. Members of this receptor subfamily are heterotetrameric glycoproteins consisting of two extracellular ligand-binding alpha-subunits and two transmembrane catalytic beta-subunits. No dimer mentioned and PISA says monomer - automatic transfer from 1k3a 1p4o_2 PROBNOT 1 1 NPS NPS 14501110 11694888 Fragment - Paper says: The IGF1 receptor is structurally homologous to the insulin receptor. Members of this receptor subfamily are heterotetrameric glycoproteins consisting of two extracellular ligand-binding alpha-subunits and two transmembrane catalytic beta-subunits. No dimer mentioned and PISA says monomer - automatic transfer from 1k3a 1p4u NO 1 1 NPS NPS 12858162 12858162 GAE domain is part of GGA proteins which are monomeric as said below in the paper: In addition to the AP complexes, several monomeric proteins have recently been shown to function as adaptors for other subsets of transmembrane proteins. Among these monomeric adaptors are the GGA proteins GGA1, GGA2 and GGA3, which sort mannose-6-phosphate receptors and other receptors from the trans-Golgi network (TGN) to endosomes. 1p50 NO 1 1 NPS NPS 12732621 12732621 Paper says: Arginine kinase is widespread in invertebrates and may be the primordial enzyme because of its widely available substrate, monomeric structure, and presence in protozoa -- interesting: very good family for QS evolution (close monomer, dimer and octamer) -- Annotation transfered from 1p52 1p51_1 NO 2 2 C2 C2 12853489 12853489 Domain Swapped dimer - automatic transfer from 1p71 1p51_2 NO 2 2 C2 C2 12853489 12853489 Domain Swapped dimer - automatic transfer from 1p71 1p52 NO 1 1 NPS NPS 12732621 12732621 Paper says: Arginine kinase is widespread in invertebrates and may be the primordial enzyme because of its widely available substrate, monomeric structure, and presence in protozoa -- interesting: very good family for QS evolution (close monomer, dimer and octamer) 1p56 NO 1 1 NPS NPS 14756565 0 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1p59 PROBNOT 1 1 NPS NPS 12840008 12840008 -- Annotation transfered from 1orn 1p5c_1 NO 1 1 NPS NPS 14756565 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1p5c_2 NO 1 1 NPS NPS 14756565 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1p5c_3 NO 1 1 NPS NPS 14756565 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1p5c_4 NO 1 1 NPS NPS 14756565 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1p5f NO 2 2 C2 C2 12855764 12855764 -- Annotation transfered from 1ucf 1p5q PROBYES 3 1 NS NPS 15159550 15159550 Paper implies monomeric -- Annotation transfered from 1qz2 1p5t NA 2 1 NS NPS 14607833 14607833 Oligomeric state not mentioned --> Probably monomner but PISA doesnt agree. 1p63_1 PROBNOT 1 1 NPS NPS 14627732 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1p63_2 PROBNOT 1 1 NPS NPS 14627732 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1p64 NO 1 1 NPS NPS 12963380 12963380 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1p6h NO 2 2 C2 C2 14718923 0 Clear dimer -- Annotation transfered from 1m00 1p6i NO 2 2 C2 C2 14718923 0 Clear dimer -- Annotation transfered from 1m00 1p6j NO 2 2 C2 C2 14718923 0 Clear dimer -- Annotation transfered from 1m00 1p6k NO 2 2 C2 C2 14718923 0 Clear dimer -- Annotation transfered from 1m00 1p6l NO 2 2 C2 C2 14718923 0 Clear dimer -- Annotation transfered from 1fol 1p6m NO 2 2 C2 C2 14718923 0 Clear dimer -- Annotation transfered from 1fol 1p6n NO 2 2 C2 C2 14718923 0 Clear dimer -- Annotation transfered from 1fol 1p6p PROBNOT 1 1 NPS NPS 12846568 12846568 SP says monomer 1p6w NO 1 1 NPS NPS 12906828 9571044 alpha-Amylases (a-1,4 glucan-4-glucanohydrolase, EC 3.2.1.1) are monomeric enzymes that catalyse the hydrolysis of internal a-D-(1,4) glucosidic linkages in starch and related oligo- and polysaccharides with release of malto-oligosaccharides and glucose in the alpha-anomeric form. 1p6y NO 1 1 NPS NPS 12963380 12963380 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1p6z NO 2 2 C2 C2 0 0 -- Annotation transfered from 1jhg 1p71 NO 2 2 C2 C2 12853489 12853489 Domain Swapped dimer 1p74 PROBNOT 2 2 C2 C2 12837789 12837789 Very interesting, even though the binding surface is not very large, it is the same that is found in e. coli, which is true. 1p77 PROBNOT 1 1 NPS NPS 12837789 12837789 The interface of the dimer (1p74) is quite weak so it would probably be in an equilibrium. 1p78 NO 2 2 C2 C2 12853489 12853489 Domain Swapped dimer -- Annotation transfered from 1p71 1p7l NO 4 4 D2 D2 14967023 14967023 -- Annotation transfered from 1rg9 1p7o YES 6 2 C2 C2 15720395 15720395 1p7p PROBNOT 1 1 NPS NPS 12946347 12946347 Paper says: Crystals of a monomeric fragment of Escherichia coli methionyl-tRNA synthetase (551 N-terminal residues) have been used to determine the 3D-structure of the free enzyme 1p7r PROBNOT 1 1 NPS NPS 14556625 14556625 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1p7s NO 1 1 NPS NPS 12963380 12963380 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1p7v PROBNOT 1 1 NPS NPS 0 0 1p7w PROBNOT 1 1 NPS NPS 0 0 -- Annotation transfered from 1p7v 1p8c NO 6 6 D3 D3 0 0 Interface geometry conserved with 1vke (90%) 1p8h YES 6 4 C3 C3 12842471 12842471 BU changed since last release and is now incorrect - SP says trimer -- Annotation transfered from 1p8u 1p8i NO 3 3 C3 C3 12842471 12842471 SP says trimer -- Annotation transfered from 2brd 1p8m NO 3 3 C3 C3 12820884 12820884 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference -- Annotation transfered from 1hqx 1p8n NO 3 3 C3 C3 12820884 12820884 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference -- Annotation transfered from 1hqx 1p8o NO 3 3 C3 C3 12820884 12820884 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference -- Annotation transfered from 1hqx 1p8p NO 3 3 C3 C3 12820884 12820884 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference -- Annotation transfered from 1hqx 1p8q NO 3 3 C3 C3 12820884 12820884 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference -- Annotation transfered from 1hqx 1p8r_1 NO 3 3 C3 C3 12820884 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automatic transfer from 1hqx 1p8r_2 NO 3 3 C3 C3 12820884 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automatic transfer from 1hqx 1p8s NO 3 3 C3 C3 12820884 12820884 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference -- Annotation transfered from 1hqx 1p8u YES 6 3 C3 C3 12842471 12842471 BU changed since last release and is now incorrect - SP says trimer 1p92 PROBYES 1 2 NPS C2 12837782 12837782 Identicals are dimers and PISa says dimer -- Annotation transfered from 1bi0 1p93_1 NA 1 1 NPS NPS 12686538 12686538 Paper talk about a homodimer - but might as well be a monomer - there is another homodimer proven to be functional (100% id) but different interaction ?! Very stange case - still interesting - automatic transfer from 1nhz 1p93_2 NA 1 1 NPS NPS 12686538 12686538 Paper talk about a homodimer - but might as well be a monomer - there is another homodimer proven to be functional (100% id) but different interaction ?! Very stange case - still interesting - automatic transfer from 1nhz 1p93_3 NA 1 1 NPS NPS 12686538 12686538 Paper talk about a homodimer - but might as well be a monomer - there is another homodimer proven to be functional (100% id) but different interaction ?! Very stange case - still interesting - automatic transfer from 1nhz 1p93_4 NA 1 1 NPS NPS 12686538 12686538 Paper talk about a homodimer - but might as well be a monomer - there is another homodimer proven to be functional (100% id) but different interaction ?! Very stange case - still interesting - automatic transfer from 1nhz 1p9e PROBNOT 2 2 C2 C2 0 15103151 PAper says nothing but - domain swapped interface 1p9p YES 1 2 NPS C2 14583191 14583191 Interface geometry conserved with 1uaj (79% id) 1p9r NA 1 1 NPS NPS 14556751 14556751 Paper says: Studies of the multimerization state of GspE proteins have been conflicting - They think other components are necessary for oligomerization 1p9w NA 1 1 NPS NPS 14556751 14556751 Paper says: Studies of the multimerization state of GspE proteins have been conflicting - They think other components are necessary for oligomerization -- Annotation transfered from 1p9r 1pa0 NO 2 2 C2 C2 14623331 14623331 Paper says they are dimers - SP says monomer but is apparently wrong? - paper is good review of QS state of Lys49 PLA2 - intetesting 1pa1 PROBNOT 1 1 NPS NPS 12748196 12748196 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1pa3 NO 2 2 C2 C2 12972411 12972411 paper says glutathione S-transferases are functional dimers. -- Annotation transfered from 1q4j 1pa7 PROBNOT 1 1 NPS NPS 12857735 12857735 -- Annotation transfered from 1ueg 1pa9 PROBNOT 1 1 NPS NPS 12810712 12810712 -- Annotation transfered from 1yts 1pad PROBNOT 1 1 NPS NPS 952885 952885 Papain is a 23,400-dalton single polypeptide -- Annotation transfered from 9pap 1pae NO 6 6 D3 D3 14604526 14604526 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 1pah YES 1 2 NPS C2 9406548 9406548 They speak of the: dimeric catalytic domain (residues 117-424) - Even though the tetramerization helix is missing, it should still be a dimer. -- Annotation transfered from 1dmw 1pal PROBNOT 1 1 NPS NPS 1880797 1880797 1paz NO 1 1 NPS NPS 3271558 3271558 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 -- Annotation transfered from 8paz 1pb7 PROBNOT 1 1 NPS NPS 12805203 12805203 Does not crystallizes as a dimer, probably because as it is a membranne prot, the association is weak. -- Authors discuss where could the real interface be by comparing the receptor to other proteins --> good example to support my work, i.e. they do not have standard for comparison. I could put this in the letter to the editors - good interesting example -- Annotation transfered from 1pb9 1pb8 PROBNOT 1 1 NPS NPS 12805203 12805203 Does not crystallizes as a dimer, probably because as it is a membranne prot, the association is weak. -- Authors discuss where could the real interface be by comparing the receptor to other proteins --> good example to support my work, i.e. they do not have standard for comparison. I could put this in the letter to the editors - good interesting example -- Annotation transfered from 1pb9 1pb9 PROBNOT 1 1 NPS NPS 12805203 12805203 Does not crystallizes as a dimer, probably because as it is a membranne prot, the association is weak. -- Authors discuss where could the real interface be by comparing the receptor to other proteins --> good example to support my work, i.e. they do not have standard for comparison. I could put this in the letter to the editors - good interesting example 1pbb NO 2 2 C2 C2 7520279 7520279 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1pbc NO 2 2 C2 C2 7520279 7520279 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1pbd NO 2 2 C2 C2 7520279 7520279 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1pbe NO 2 2 C2 C2 2553983 2553983 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1pbf NO 2 2 C2 C2 7520279 7520279 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1pbg_1 PROBNOT 1 1 NPS NPS 8535789 9223646 Paper says nothing about a dimer - PISA says monomer - automatic transfer from 2pbg 1pbg_2 PROBNOT 1 1 NPS NPS 8535789 9223646 Paper says nothing about a dimer - PISA says monomer - automatic transfer from 2pbg 1pbh PROBNOT 1 1 NPS NPS 8617355 8617355 SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond - here only one chain 1pbi YES 4 2 C2 C2 9887273 9887273 Paper says dimer 1pbk PROBNOT 1 1 NPS NPS -1 0 Similar proteins are monomers, PISA says monomer 1pbn NO 3 3 C3 C3 9585525 9585525 Paper says trimer -- Annotation transfered from 1v48 1pbo NO 2 2 C2 C2 8901871 8901871 Domain Swapped dimer -- Annotation transfered from 1gt1 1pbq PROBYES 2 1 NS NPS 12805203 12805203 BU changed since last release and is now incorrect - Native structure should be a dimer but crystallizes as a monomer (membranne protein) 1pc4 NO 1 1 NPS NPS 12962482 12962482 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1pc5 NO 1 1 NPS NPS 12962482 12962482 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 1pcg NO 2 2 C2 C2 13679575 13679575 paper says dimer -- Annotation transfered from 1err 1pch PROBNOT 1 1 NPS NPS 7582895 7582895 Paper says it ressembles E. coli prot (which is monomeric), PISA says monomer 1pci_1 PROBNOT 1 1 NPS NPS 8939744 8769310 SP says monomer and family monomeric - automatic transfer from 1meg 1pci_2 PROBNOT 1 1 NPS NPS 8939744 8769310 SP says monomer and family monomeric - automatic transfer from 1meg 1pci_3 PROBNOT 1 1 NPS NPS 8939744 8769310 SP says monomer and family monomeric - automatic transfer from 1meg 1pck NO 4 4 D2 D2 14675946 14675946 Paper says tetramer -- Annotation transfered from 1fws 1pcq NO 21 21 NPS NPS 14517228 14517228 -- error in symmetry calculation, I dont know why -- Annotation transfered from 1aon 1pcs PROBYES 2 1 C2 NPS 9466912 9466912 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) - Paper does not mention dimer and PISA says monomer 1pcw NO 4 4 D2 D2 14675946 14675946 Paper says tetramer -- Annotation transfered from 1fws 1pcx PROBNOT 1 1 NPS NPS 12941276 12941276 Paper implies monomer (in terms of homomeric state). But binds to Bet1, Sed5, and Sec22. -- Annotation transfered from 1pd1 1pcz NO 2 2 C2 C2 9000631 9000631 Interface geometry conserved with 1mp9 (42%) 1pd0 PROBNOT 1 1 NPS NPS 12941276 12941276 Paper implies monomer (in terms of homomeric state). But binds to Bet1, Sed5, and Sec22. -- Annotation transfered from 1pd1 1pd1 PROBNOT 1 1 NPS NPS 12941276 12941276 Paper implies monomer (in terms of homomeric state). But binds to Bet1, Sed5, and Sec22. 1pd2 NO 2 2 C2 C2 9323136 9323136 1pd8 PROBNOT 1 1 NPS NPS 12925791 12925791 -- Annotation transfered from 1s3u 1pd9 PROBNOT 1 1 NPS NPS 12925791 12925791 -- Annotation transfered from 1s3u 1pdh NO 2 2 C2 C2 7756982 7756982 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1pdr YES 6 1 D3 NPS 8757139 8757139 This is just a domain of a large protein. 15504326 says: Single-particle electron microscopy (EM) combined with biochemical measurements revealed the molecular shape of SAP97 and a monomer-dimer transition that depended on the N-terminal L27 domain. 1pdv NO 2 2 C2 C2 12761214 12761214 -- Annotation transfered from 1ucf 1pdw_1 PROBNOT 2 2 C2 C2 12761214 12914946 BU changed since last release and is now corrected - Homodimeric - automaticaly inferred from 1ps4 1pdw_2 PROBNOT 2 2 C2 C2 12761214 12914946 BU changed since last release and is now corrected - Homodimeric - automaticaly inferred from 1ps4 1pdw_3 PROBNOT 2 2 C2 C2 12761214 12914946 BU changed since last release and is now corrected - Homodimeric - automaticaly inferred from 1ps4 1pdw_4 PROBNOT 2 2 C2 C2 12761214 12914946 BU changed since last release and is now corrected - Homodimeric - automaticaly inferred from 1ps4 1pe0 NO 2 2 C2 C2 12761214 12761214 -- Annotation transfered from 1ucf 1pe1 NO 4 4 D2 D2 14675946 14675946 Paper says tetramer -- Annotation transfered from 1fws 1pe5 PROBNOT 1 1 NPS NPS 0 0 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1pe6 PROBNOT 1 1 NPS NPS 1860874 1860874 Papain is a 23,400-dalton single polypeptide -- Annotation transfered from 9pap 1pe7 PROBNOT 1 1 NPS NPS 0 0 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1pe8 PROBNOT 1 1 NPS NPS 0 0 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1pea PROBYES 2 1 C2 NPS 7813419 7813419 No dimer mentioned in the paper, like E coli, I assume that it is a big complex and that protein is present in one copy only. Plus PISA says monomer -- Annotation transfered from 1qnl 1peb PROBNOT 1 1 NPS NPS 12794084 12794084 EcoCyc says monomer -- Annotation transfered from 1nl5 1ped NO 4 4 D2 D2 15299659 0 -- Annotation transfered from 1jqb 1pek PROBNOT 1 1 NPS NPS 8340410 8340410 -- Annotation transfered from 1p7v 1per PROBNOT 2 2 C2 C2 8081737 8081737 The repressor of phage 434 binds to a set of operator sites as a homodimer. 1pew YES 2 1 NS NPS 15227639 15227639 Mutant protein, should be a dimer but crystal packing is altered. 1pex PROBNOT 1 1 NPS NPS 8969305 8969305 Paper says nothing and PISA says monomer 1pey PROBYES 3 1 NS NPS 15039551 15255896 BU changed since last release and is now incorrect - Spo0F is a monomer in both unphosphorylated and phosphorylated forms. 1pez NO 1 1 NPS NPS 12809508 12809508 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1pf3 PROBNOT 1 1 NPS NPS 12794077 12794077 Paper says nothing, PISA says monomer -- Annotation transfered from 1n68 1pf5 NO 3 3 C3 C3 0 0 Interface geometry conserved with 1qah (30%) 1pf7 NO 3 3 C3 C3 13679061 13679061 Paper says trimer -- Annotation transfered from 1ula 1pf8 NO 1 1 NPS NPS 14550307 14550307 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1pf9 NO 21 21 NPS NPS 14517228 0 -- error in symmetry calculation, I dont know why -- Annotation transfered from 1aon 1pff PROBNOT 4 4 D2 D2 0 0 Related structures are tetramers and PISA says tetramer 1pfg PROBNOT 1 1 NPS NPS 8976553 8976553 -- Annotation transfered from 1p7v 1pfk NO 4 4 D2 D2 2975709 2975709 12015149: The eubacterial ATP-dependent PFKs, of which the E. coli enzyme is the best-studied example, are allosterically regulated homotetramers 1pfp NO 1 1 NPS NPS 14604526 14604526 1pfq NO 2 2 C2 C2 12832764 12832764 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. -- Annotation transfered from 1tkr 1pfu PROBNOT 1 1 NPS NPS 12946347 12946347 Paper says: Crystals of a monomeric fragment of Escherichia coli methionyl-tRNA synthetase (551 N-terminal residues) have been used to determine the 3D-structure of the free enzyme -- Annotation transfered from 1p7p 1pfv PROBNOT 1 1 NPS NPS 12946347 12946347 Paper says: Crystals of a monomeric fragment of Escherichia coli methionyl-tRNA synthetase (551 N-terminal residues) have been used to determine the 3D-structure of the free enzyme -- Annotation transfered from 1p7p 1pfw PROBNOT 1 1 NPS NPS 12946347 12946347 Paper says: Crystals of a monomeric fragment of Escherichia coli methionyl-tRNA synthetase (551 N-terminal residues) have been used to determine the 3D-structure of the free enzyme -- Annotation transfered from 1p7p 1pfy PROBNOT 1 1 NPS NPS 12946347 12946347 Paper says: Crystals of a monomeric fragment of Escherichia coli methionyl-tRNA synthetase (551 N-terminal residues) have been used to determine the 3D-structure of the free enzyme -- Annotation transfered from 1p7p 1pg8 NO 4 4 D2 D2 0 0 Paper says tetramer - but says that dimer is active - interesting example for saying that dimer is functional intermediate -- Annotation transfered from 1gc0 1pga PROBNOT 1 1 NPS NPS 8161530 8161530 12379842 implies it is monomeric, PISA also says monomeric 1pgb PROBNOT 1 1 NPS NPS 8161530 8161530 12379842 implies it is monomeric, PISA also says monomeric -- Annotation transfered from 1pga 1pge NO 2 2 C2 C2 8652509 8652509 -- Annotation transfered from 1cqe 1pgf NO 2 2 C2 C2 8652509 8652509 -- Annotation transfered from 1cqe 1pgg NO 2 2 C2 C2 8652509 8652509 -- Annotation transfered from 1cqe 1pgt NO 2 2 C2 C2 9245401 9245401 -- Annotation transfered from 9gss 1pgu YES 2 1 C2 NPS 12807914 12807914 Dynamic light-scattering experiments using a Protein Solutions Dynapro 99 instrument on purified protein at 0.2 mg/ml concentration indicated that Aip1p exists as a monodisperse monomer with a molecular mass of 61.3 kDa reasonably close to the predicted molecular mass - PISA wrong 1pgx PROBYES 1 1 NPS NPS 1420164 1420164 12379842 implies it is monomeric, PISA also says monomeric -- Annotation transfered from 2igd 1ph0 PROBNOT 1 1 NPS NPS 12877578 12877578 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1pha PROBNOT 1 1 NPS NPS 8485133 8485133 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1phb PROBNOT 1 1 NPS NPS 8485133 8485133 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1phc PROBNOT 1 1 NPS NPS 3768350 3768350 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1phd PROBNOT 1 1 NPS NPS 3442650 3442650 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1phe PROBNOT 1 1 NPS NPS 3442650 3442650 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1phf PROBNOT 1 1 NPS NPS 3442650 3442650 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1phg PROBNOT 1 1 NPS NPS 3442650 3442650 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1phh NO 2 2 C2 C2 3351945 3351945 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1phk PROBYES 1 2 NPS C2 7663944 7663944 Paper says it is probably a dimer - PISA is wrong here (overlaping structures) - note that this kinase contains 4 copies of alpha,beta,gamma,delta! - interesting -- Annotation transfered from 2phk 1phq NO 4 4 D2 D2 0 0 paper says homotetramer -- Annotation transfered from 1d9e 1pht PROBNOT 1 1 NPS NPS 8648629 8648629 PAper says nothing, PISA says monomer 1phw NO 4 4 D2 D2 16023668 16023668 paper says homotetramer -- Annotation transfered from 1d9e 1pi2 PROBNOT 6 6 D3 D3 1730730 1730730 Paper does not say anything - PISA says hexamer 1pi3 NO 4 4 D2 D2 0 9665697 Interface geometry conserved with 1ovm (25%) - automatic transfer from 1bfd 1pi4_1 PROBNOT 1 1 NPS NPS 14661960 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1pi4_2 PROBNOT 1 1 NPS NPS 14661960 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1pi5_1 PROBNOT 1 1 NPS NPS 14661960 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1pi5_2 PROBNOT 1 1 NPS NPS 14661960 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1pi6 NO 1 1 NPS NPS 12807914 12807914 Dynamic light-scattering experiments using a Protein Solutions Dynapro 99 instrument on purified protein at 0.2 mg/ml concentration indicated that Aip1p exists as a monodisperse monomer with a molecular mass of 61.3 kDa reasonably close to the predicted molecular mass - PISA wrong 1pie PROBNOT 1 1 NPS NPS 12796487 12796487 Paper says: The quaternary structures of the galactokinases obtained from E. coli, yeast, and human are monomeric, whereas that isolated from Vicia faba seeds is dimeric. Examination of the packing arrangement of the L. lactis enzyme in the crystalline lattice suggests that it is also monomeric. 1pil NO 3 3 C3 C3 7866749 7866749 Interface geometry conserved with 1qy7 (66%) 1pin PROBNOT 2 2 C2 C2 9200606 10932246 BU changed since last release and is now corrected - Dimer according to PISA, and also according to me given the interface between the 2 polyp. chains in the ASU. But apparently no biochemical evidence. - automaticaly inferred from 1f8a 1pio PROBYES 2 1 C2 NPS 8869640 8869640 Class A betalactamase are apparently monomeric in solution (said in paper) -- Annotation transfered from 1kgf 1pip PROBNOT 1 1 NPS NPS 1445868 1445868 Papain is a 23,400-dalton single polypeptide -- Annotation transfered from 9pap 1piq NO 3 3 C3 C3 9837709 9837709 Paper says trimer -- Annotation transfered from 1gcm 1piw NO 2 2 C2 C2 15289102 15289102 -- Annotation transfered from 1q1n 1pj8 PROBNOT 1 1 NPS NPS 8811735 8811735 -- Annotation transfered from 1p7v 1pj9 NO 1 1 NPS NPS 14705029 14705029 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 1pja PROBNOT 1 1 NPS NPS 12855696 12855696 Paper says nothing, PISA says monomer and related prots are monomeric 1pjb NO 6 6 D3 D3 9665169 9665169 Paper says hexameric -- Annotation transfered from 1say 1pjc NO 6 6 D3 D3 9665169 9665169 Paper says hexameric -- Annotation transfered from 1say 1pjh NO 6 6 D3 D3 14741345 14741345 The variable mode of assembly of the trimeric disks of the crotonase superfamily - interesting 1pji PROBNOT 1 1 NPS NPS 16243784 0 SP says monomer and a review says that these prots are monomeric -- Annotation transfered from 1tdz 1pjj PROBNOT 1 1 NPS NPS 16243784 12065399 SP says monomer and a review says that these prots are monomeric -- Annotation transfered from 1tdz 1pjk NO 1 1 NPS NPS 12860116 12860116 alpha2 beta2 - alpha not in contact 1pjm PROBNOT 1 1 NPS NPS 12695505 12695505 Paper says: suggesting that both proteins are monomeric under these conditions -- Annotation transfered from 1iq1 1pjn PROBNOT 1 1 NPS NPS 12695505 12695505 Paper says: suggesting that both proteins are monomeric under these conditions -- Annotation transfered from 1iq1 1pjp PROBNOT 1 1 NPS NPS 9931257 10208809 Paper says nothing, PISA says monomer -- Annotation transfered from 1nn6 1pk4 PROBNOT 1 1 NPS NPS 1657148 1657148 This is just a very small domain of much a larger protein so probably monomeric 1pk7 NO 6 6 D3 D3 12937174 12937174 Paper and SP say hexamer -- Annotation transfered from 1ovg 1pk8_1 NO 4 4 D2 D2 14688264 14688264 Paper says: An ATP-stabilized tetramer of rSynI-ABC is observed during velocity sedimentation and size-exclusion chromatographic experiments. - automatic transfer from 1px2 1pk8_2 NO 4 4 D2 D2 14688264 14688264 Paper says: An ATP-stabilized tetramer of rSynI-ABC is observed during velocity sedimentation and size-exclusion chromatographic experiments. - automatic transfer from 1px2 1pk9 NO 6 6 D3 D3 12937174 12937174 Paper and SP say hexamer -- Annotation transfered from 1ovg 1pke NO 6 6 D3 D3 12937174 12937174 Paper and SP say hexamer -- Annotation transfered from 1ovg 1pkf PROBNOT 1 1 NPS NPS 12933799 12933799 11304120 says P450s are monomeric enzymes -- Annotation transfered from 1q5d 1pkg_1 NO 1 1 NPS NPS 12824176 15123710 Paper says: The binding of a stem cell factor dimer to the extracellular Ig domains of c-Kit causes two c-Kit RPTKs to dimerize - ligand induced dimerization - automatic transfer from 1t45 1pkg_2 NO 1 1 NPS NPS 12824176 15123710 Paper says: The binding of a stem cell factor dimer to the extracellular Ig domains of c-Kit causes two c-Kit RPTKs to dimerize - ligand induced dimerization - automatic transfer from 1t45 1pkh YES 2 6 NS D3 12909016 12909016 Paper says: DCD-DUT is a hexamer 1pkj YES 2 6 NS D3 12909016 12909016 Paper says: DCD-DUT is a hexamer -- Annotation transfered from 1pkh 1pkk YES 2 6 NS D3 12909016 12909016 Paper says: DCD-DUT is a hexamer -- Annotation transfered from 1pkh 1pkm NO 4 4 D2 D2 15299671 15299671 Paper and SP say tetramer 1pkn YES 1 4 NPS D2 8193145 8193145 15299671 says tetramer 1pko PROBNOT 1 1 NPS NPS 12874380 12874380 Dimeric form not found in crystal - probably due to the fact that it exists in a monomer-dimer equilibrium (involved in cell-cell interactions) - interesting 1pkr PROBNOT 1 1 NPS NPS 8054447 8054447 Real protein 4500 aa! So monomeric seems right 1pkw NO 2 2 C2 C2 0 0 glutathione S-transferases are functional dimers. 1pky NO 4 4 D2 D2 8591049 8591049 Interface geometry conserved with 1pkm (50%) 1pkz NO 2 2 C2 C2 0 0 glutathione S-transferases are functional dimers. -- Annotation transfered from 1pkw 1pl1 NO 2 2 C2 C2 0 0 glutathione S-transferases are functional dimers. -- Annotation transfered from 1pkw 1pl2 NO 2 2 C2 C2 0 0 glutathione S-transferases are functional dimers. -- Annotation transfered from 1pkw 1pl4 NO 4 4 D2 D2 14638684 14638684 Paper says tetramer -- Annotation transfered from 1n0j 1pl9 NO 4 4 D2 D2 0 0 paper says homotetramer -- Annotation transfered from 1d9e 1plc PROBNOT 1 1 NPS NPS 1492962 1492962 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) -- Annotation transfered from 2pcy 1plf PROBNOT 4 4 D2 D2 2914894 2914894 SP says tetramer 1plj PROBYES 2 1 C2 NPS 15299412 0 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 1plk PROBYES 2 1 C2 NPS 15299412 0 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 1pll PROBYES 2 1 C2 NPS 15299412 0 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 1plr NA 1 3 NPS C3 8001157 8001157 Should be a trimer - check the paper 1pm5 PROBNOT 1 1 NPS NPS 16243784 0 SP says monomer and a review says that these prots are monomeric -- Annotation transfered from 1tdz 1pm7 NO 2 2 C2 C2 12951098 12951098 Interface geometry conserved with 1rtv (40%) 1pm9 NO 4 4 D2 D2 14638684 14638684 Paper says tetramer -- Annotation transfered from 1n0j 1pmb_1 NO 1 1 NPS NPS 2383370 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1pmb_2 NO 1 1 NPS NPS 2383370 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1pmd PROBNOT 1 1 NPS NPS 8605631 8605631 1pme NO 1 1 NPS NPS 9827991 9827991 1pmh PROBNOT 1 1 NPS NPS 15210353 15210353 Paper says nothing, PISA says monomer 1pmj PROBNOT 1 1 NPS NPS 15210353 15210353 Paper says nothing, PISA says monomer -- Annotation transfered from 1pmh 1pmk_1 PROBNOT 1 1 NPS NPS 8069221 1657148 This is just a very small domain of much a larger protein so probably monomeric - automatic transfer from 1pk4 1pmk_2 PROBNOT 1 1 NPS NPS 8069221 1657148 This is just a very small domain of much a larger protein so probably monomeric - automatic transfer from 1pk4 1pmm NO 6 6 D3 D3 12912902 12912902 Paper says hexamer -- Annotation transfered from 1pmo 1pmn PROBNOT 1 1 NPS NPS 12954329 12954329 -- Annotation transfered from 1pmv 1pmo NO 6 6 D3 D3 12912902 12912902 Paper says hexamer 1pmq PROBNOT 1 1 NPS NPS 12954329 12954329 -- Annotation transfered from 1pmv 1pmt NO 2 2 C2 C2 9655824 9655824 Interface geometry conserved with 1e6b (29%) 1pmu PROBNOT 1 1 NPS NPS 12954329 12954329 -- Annotation transfered from 1pmv 1pmv PROBNOT 1 1 NPS NPS 12954329 12954329 1pmy PROBNOT 1 1 NPS NPS 15299445 0 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 1pn3_1 PROBNOT 1 1 NPS NPS 12874381 12874381 BU changed since last release and is now corrected - Annotated during the 3D Complex curation - automaticaly inferred from 1pnv 1pn3_2 PROBNOT 1 1 NPS NPS 12874381 12874381 BU changed since last release and is now corrected - Annotated during the 3D Complex curation - automaticaly inferred from 1pnv 1pn9 NO 2 2 C2 C2 14646079 14646079 1pnc PROBNOT 1 1 NPS NPS 15299368 0 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) -- Annotation transfered from 2pcy 1pnd PROBNOT 1 1 NPS NPS 15299368 0 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) -- Annotation transfered from 2pcy 1pne PROBNOT 1 1 NPS NPS 8046751 8046751 SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio 1pnv PROBYES 2 1 NS NPS 12874381 12874381 Annotated during the 3D Complex curation 1po5 NO 1 1 NPS NPS 14563924 14563924 Paper says monomer dimer equilibrium 1po7 NO 4 4 D2 D2 0 9665697 Interface geometry conserved with 1ovm (25%) - automatic transfer from 1bfd 1po8 PROBNOT 1 1 NPS NPS 0 0 Paper does not discuss oligomeric state - PISA says monomer -- Annotation transfered from 1tc8 1po9_1 PROBYES 1 8 NPS D4 12946361 12718528 BU changed since last release and is now incorrect - Paper says: The quaternary structure of the enzyme is octameric and can be aptly described as a tetramer of dimers. - automaticaly inferred from 1onw 1po9_2 PROBYES 1 8 NPS D4 12946361 12718528 BU changed since last release and is now incorrect - Paper says: The quaternary structure of the enzyme is octameric and can be aptly described as a tetramer of dimers. - automaticaly inferred from 1onw 1poa NA 1 1 NPS NPS 2274785 2274785 After looking for 1h I cant find a clear answer. I give up 1pob NA 2 2 C2 C2 2274787 2274787 After looking for 1h I cant find a clear answer. I give up 1poc NA 2 1 C2 NPS 2274788 2274788 No access to paper, PISA also says dimer -- I do not believe it (Most PL2 are monomeric) 1pod PROBYES 2 1 C2 NPS 1948070 8979149 Human PLA predominantly exists as a monomer 1poe PROBYES 2 1 NS NPS 1948070 8979149 Human PLA predominantly exists as a monomer 1poh NO 1 1 NPS NPS 8226757 8226757 E. coli HPr is a small, monomeric protein -- Annotation transfered from 1cm2 1poj_1 PROBYES 1 8 NPS D4 12946361 12718528 BU changed since last release and is now incorrect - Paper says: The quaternary structure of the enzyme is octameric and can be aptly described as a tetramer of dimers. - automaticaly inferred from 1onw 1poj_2 PROBYES 1 8 NPS D4 12946361 12718528 BU changed since last release and is now incorrect - Paper says: The quaternary structure of the enzyme is octameric and can be aptly described as a tetramer of dimers. - automaticaly inferred from 1onw 1pok_1 PROBYES 1 8 NPS D4 12946361 12718528 BU changed since last release and is now incorrect - Paper says: The quaternary structure of the enzyme is octameric and can be aptly described as a tetramer of dimers. - automaticaly inferred from 1onw 1pok_2 PROBYES 1 8 NPS D4 12946361 12718528 BU changed since last release and is now incorrect - Paper says: The quaternary structure of the enzyme is octameric and can be aptly described as a tetramer of dimers. - automaticaly inferred from 1onw 1pop PROBNOT 1 1 NPS NPS 8416808 8416808 Papain is a 23,400-dalton single polypeptide -- Annotation transfered from 9pap 1pow NO 4 4 D2 D2 8145244 8145244 Interface geometry conserved with 1ovm (23%) 1pox NO 4 4 D2 D2 8145244 8145244 Interface geometry conserved with 1ovm (23%) -- Annotation transfered from 1pow 1pp2 PROBNOT 2 2 C2 C2 4019493 4019493 SP says homodimer 1pp3_1 PROBNOT 1 1 NPS NPS 14684896 10504569 BU changed since last release and is now corrected - Thaumatin is a stable monomeric protein of 22kDa - automaticaly inferred from 1thw 1pp3_2 PROBNOT 1 1 NPS NPS 14684896 10504569 BU changed since last release and is now corrected - Thaumatin is a stable monomeric protein of 22kDa - automaticaly inferred from 1thw 1ppa NO 1 1 NPS NPS 2120215 2120215 Paper: ACL myotoxin presents a monomer in the asymmetric unit of all three crystal forms described here, and this monomeric behavior is consistent with dynamic light scattering analysis carried out in solution under the crystallization conditions used here. - still they say that related proteins (Lys49-PLA2 myotoxins) are dimeric. -- Annotation transfered from 1s8i 1ppc PROBNOT 1 1 NPS NPS 2226434 2226434 -- Annotation transfered from 1az8 1ppd PROBNOT 1 1 NPS NPS -1 0 Papain is a 23,400-dalton single polypeptide -- Annotation transfered from 9pap 1ppg PROBYES 3 1 C3 NPS 3391280 10581030 Neutrophil elastase is a monomeric glycoprotein 1pph PROBNOT 1 1 NPS NPS 1879520 1879520 -- Annotation transfered from 1az8 1ppk NO 1 1 NPS NPS 1606144 1606144 -- Annotation transfered from 1bxo 1ppl NO 1 1 NPS NPS 1606144 1606144 -- Annotation transfered from 1bxo 1ppm NO 1 1 NPS NPS 1606144 1606144 -- Annotation transfered from 1bxo 1ppn PROBNOT 1 1 NPS NPS -1 0 Papain is a 23,400-dalton single polypeptide -- Annotation transfered from 9pap 1ppo PROBNOT 1 1 NPS NPS -1 0 SP says monomer and family monomeric -- Annotation transfered from 1meg 1ppp PROBNOT 1 1 NPS NPS 1445241 1445241 Papain is a 23,400-dalton single polypeptide -- Annotation transfered from 9pap 1ppv PROBYES 2 1 C2 NPS 15643873 15643873 Seems to be a monomer - PISA would be wrong -- Annotation transfered from 1nfs 1ppw PROBYES 2 1 C2 NPS 15643873 15643873 Seems to be a monomer - PISA would be wrong -- Annotation transfered from 1nfs 1ppz PROBNOT 1 1 NPS NPS 12937176 12937176 -- Annotation transfered from 1gdn 1pq5 PROBNOT 1 1 NPS NPS 12937176 12937176 -- Annotation transfered from 1gdn 1pq7 PROBNOT 1 1 NPS NPS 12937176 12937176 -- Annotation transfered from 1gdn 1pq8 PROBNOT 1 1 NPS NPS 12937176 12937176 -- Annotation transfered from 1gdn 1pqa PROBNOT 1 1 NPS NPS 12937176 12937176 -- Annotation transfered from 1gdn 1pqd NO 1 1 NPS NPS 12963380 12963380 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1pqi NO 1 1 NPS NPS 12963380 12963380 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1pqj NO 1 1 NPS NPS 12963380 12963380 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1pqm NO 1 1 NPS NPS 12963380 12963380 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1pqo NO 1 1 NPS NPS 12963380 12963380 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1pqp NO 2 2 C2 C2 15272161 15272161 -- Annotation transfered from 1q2x 1pqu_1 NO 2 2 C2 C2 15272161 0 - automatic transfer from 1q2x 1pqu_2 NO 2 2 C2 C2 15272161 0 - automatic transfer from 1q2x 1pr0 NO 6 6 D3 D3 12937174 12937174 Paper and SP say hexamer -- Annotation transfered from 1ovg 1pr1 NO 6 6 D3 D3 12937174 12937174 Paper and SP say hexamer -- Annotation transfered from 1ovg 1pr2 NO 6 6 D3 D3 12937174 12937174 Paper and SP say hexamer -- Annotation transfered from 1ovg 1pr3 YES 1 2 NPS C2 15272161 0 -- Annotation transfered from 1nx6 1pr4 NO 6 6 D3 D3 12937174 12937174 Paper and SP say hexamer -- Annotation transfered from 1ovg 1pr5 NO 6 6 D3 D3 12937174 12937174 Paper and SP say hexamer -- Annotation transfered from 1ovg 1pr6 NO 6 6 D3 D3 12937174 12937174 Paper and SP say hexamer -- Annotation transfered from 1ovg 1pr9 YES 2 4 C2 D2 15103634 15103634 XRs from human and four rodents (mouse, rat, guinea pig, and hamster) are tetramers with each subunit consisting of 244 amino acid residues. 1prg NO 2 2 C2 C2 9744270 9744270 Paper says homodimer 1prh NO 2 2 C2 C2 8121489 8121489 -- Annotation transfered from 1cqe 1prn NO 3 3 C3 C3 7525973 7525973 Interface geometry conserved with 1gfn (20%) 1pro NO 2 2 C2 C2 8558507 8558507 -- Annotation transfered from 1ajx 1prq PROBNOT 1 1 NPS NPS 9774541 9774541 SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio 1prw PROBNOT 1 1 NPS NPS 14527397 14527397 -- Annotation transfered from 3cln 1prx NO 2 2 C2 C2 9587003 9587003 Interface geometry conseved with 1qmv (30%) 1pry PROBNOT 1 1 NPS NPS 14975761 14975761 In contrast, the N-terminal domains are divergent which may explain why some forms of fibrillarin apparently homodimerize (M. jannashii) while others are monomeric (P. furiosus and A. fulgidus). 1ps0 NO 2 2 C2 C2 15289102 15289102 -- Annotation transfered from 1q1n 1ps4 YES 1 2 NPS C2 12914946 12914946 Homodimeric 1ps5 NO 1 1 NPS NPS 12962625 12962625 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1ps8 YES 1 2 NPS C2 15272161 0 -- Annotation transfered from 1nx6 1psa PROBYES 2 2 C2 C2 1418819 1418819 They discuss the dimer in the paper. The enzyme is generally described as a monomer and I dont think this dimeric state is relevant as 2psg (99%) also forms a dimer but with a completely different config. 1psh NO 3 3 C3 C3 8419939 8419939 Forms trimers in many different cryst. conditions so the authors think it is biol. relevant. - The active site is hidden in the trimeric form. The paper discusses the relevance and says it is not understood why the form 94% id does not adopt a trimeric form. - Still an equilibrium exists and enzyme is monomeric when [.] < 0.05 mg/L --> could be activated when released! - interesting -- Annotation transfered from 1a3d 1psi PROBNOT 1 1 NPS NPS 8756325 8756325 Paper says nothing, forms a heterodimer with an apparent 1:1 ratio (1oph) and PISA says monomer -- Annotation transfered from 1oo8 1psj PROBNOT 1 1 NPS NPS 8636969 8636969 SP says monomer -- Annotation transfered from 1bk9 1psn PROBNOT 1 1 NPS NPS 7663352 7663352 None of the associated paper speaks about oligomeric state - PISA says monomer and related proteins are monomeric 1pso PROBNOT 1 1 NPS NPS 7663352 7663352 None of the associated paper speaks about oligomeric state - PISA says monomer and related proteins are monomeric -- Annotation transfered from 1psn 1psq NO 2 2 C2 C2 0 0 Interface geometry conserved with 1h4o (30%) 1psr NO 2 2 C2 C2 9562557 9562557 Paper says dimer -- Annotation transfered from 2psr 1psu YES 2 4 C2 D2 0 16464851 masses determined by gel filtration chromatography correspond to 67 kDa and 58kDa. Both PaaIs are therefore homotetramers. (PISA wrong - says dimer) 1pt6_1 PROBNOT 1 1 NPS NPS 14660600 14660600 - automatic transfer from 1qcy 1pt6_2 PROBNOT 1 1 NPS NPS 14660600 14660600 - automatic transfer from 1qcy 1ptf NO 1 1 NPS NPS 8126724 8126724 SP says monomer 1pth NO 2 2 C2 C2 7552725 7552725 BU changed since last release and is now corrected - 1ptk PROBNOT 1 1 NPS NPS 8253733 8253733 -- Annotation transfered from 1p7v 1pts NO 4 4 D2 D2 1390720 1390720 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1ptt PROBNOT 1 1 NPS NPS 7540771 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1ptu NA 2 2 C2 C2 7540771 7540771 Possibly relevant - check paper 1ptv PROBNOT 1 1 NPS NPS 7540771 7540771 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1ptw PROBNOT 4 4 D2 D2 14609333 14609333 the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state -- Annotation transfered from 1oyn 1pty PROBNOT 1 1 NPS NPS 9391040 9391040 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1ptz NO 2 2 C2 C2 12963370 12963370 Mammalian Cu,Zn SOD assembles into an unusually stable homodimer with exquisite substrate specificity. Interface conserved down to 50% (at least with 1jcv) -- Annotation transfered from 1n19 1pu0_1 PROBNOT 2 2 C2 C2 12963370 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1pu0_2 PROBNOT 2 2 C2 C2 12963370 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1pu0_3 PROBNOT 2 2 C2 C2 12963370 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1pu0_4 PROBNOT 2 2 C2 C2 12963370 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1pu0_5 PROBNOT 2 2 C2 C2 12963370 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1pu2 YES 1 2 NPS C2 15272161 0 -- Annotation transfered from 1nx6 1pu9 PROBNOT 1 1 NPS NPS 14536085 14536085 Paper says: Narrow line widths are consistent with gel filtration, chromatographic, and mass spectrometric results that suggest the bromodomain is monomeric in solution. -- Annotation transfered from 1q2d 1pua PROBNOT 1 1 NPS NPS 14536085 14536085 Paper says: Narrow line widths are consistent with gel filtration, chromatographic, and mass spectrometric results that suggest the bromodomain is monomeric in solution. -- Annotation transfered from 1q2d 1puc NO 2 2 C2 C2 8805536 8805536 Paper says dimer: The new p13suc1 structure extends the idea that oligomerization controls the function of p13suc1 and its homologues, and demonstrates that the unusual strand-exchange interaction is common to this family of cell-cycle control proteins. 1puo PROBYES 2 1 NS NPS 12851385 12851385 Paper says: Herein, we report the crystal structure of recombinant monomeric Fel d 1 at 1.85-A resolution 1pv2_1 NO 2 2 C2 C2 14691241 14500888 It is a homodimer but it is strange to see that the dimerization mode seems different from the one in 1izy (different surface but similar orientation). Interesting to investigate - automatic transfer from 1ons 1pv2_2 NO 2 2 C2 C2 14691241 14500888 It is a homodimer but it is strange to see that the dimerization mode seems different from the one in 1izy (different surface but similar orientation). Interesting to investigate - automatic transfer from 1ons 1pv2_3 NO 2 2 C2 C2 14691241 14500888 It is a homodimer but it is strange to see that the dimerization mode seems different from the one in 1izy (different surface but similar orientation). Interesting to investigate - automatic transfer from 1ons 1pv2_4 NO 2 2 C2 C2 14691241 14500888 It is a homodimer but it is strange to see that the dimerization mode seems different from the one in 1izy (different surface but similar orientation). Interesting to investigate - automatic transfer from 1ons 1pv8 NO 6 6 D3 D3 12897770 12897770 Paper says hexamer - Although the predominant oligomeric form of this enzyme, as inferred from many crystal structures, is that of a homo-octamer, a rare human PBGS allele, F12L, reveals the presence of a hexameric form. Rearrangement of an N-terminal arm is responsible for this oligomeric switch, which results in profound changes in kinetic behavior. -- very very interesting example! 1pv9 NO 2 2 C2 C2 15005612 15005612 Paper says dimer 1pvb PROBNOT 1 1 NPS NPS 15299738 0 -- Annotation transfered from 1pal 1pvd YES 2 4 C2 D2 8604141 8604141 Paper says tetramer -- PISA does not find 1pvf PROBYES 2 1 C2 NPS 0 0 Seems to be a monomer - PISA would be wrong -- Annotation transfered from 1nfs 1pvp YES 4 8 C4 C4 14652076 14652076 BU changed since last release and is now incorrect - -- Annotation transfered from 1kbu 1pvq YES 4 8 C4 C4 14652076 14652076 BU changed since last release and is now incorrect - -- Annotation transfered from 1kbu 1pvr YES 4 8 C4 C4 14652076 14652076 BU changed since last release and is now incorrect - -- Annotation transfered from 1kbu 1pvt YES 1 1 NPS NPS 0 0 Similar to a E. coli tetramer, PISA says it is a tetramer 1pvv NO 12 12 Tetr Tetr 14646072 14646072 Interface geometry conserved with 1ort (39%) 1pw1 PROBNOT 1 1 NPS NPS 15581896 15581896 the Streptomyces R61 and Actinomadura R39 DD-peptidases, are water-soluble monomeric proteins; (12723972) -- Annotation transfered from 1pwd 1pw2 NO 1 1 NPS NPS 12679018 12679018 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1pw3_1 PROBYES 1 2 NPS C2 15227639 10524280 BU changed since last release and is now incorrect - Classic IgV interaction - automaticaly inferred from 1cd0 1pw3_2 PROBYES 1 2 NPS C2 15227639 10524280 BU changed since last release and is now incorrect - Classic IgV interaction - automaticaly inferred from 1cd0 1pw6_1 PROBNOT 1 1 NPS NPS 14664558 0 BU changed since last release and is now corrected - - automaticaly inferred from 3ink 1pw6_2 PROBNOT 1 1 NPS NPS 14664558 0 BU changed since last release and is now corrected - - automaticaly inferred from 3ink 1pw7 NO 6 6 D3 D3 12937174 12937174 Paper and SP say hexamer -- Annotation transfered from 1ovg 1pw8 PROBNOT 1 1 NPS NPS 15581896 15581896 the Streptomyces R61 and Actinomadura R39 DD-peptidases, are water-soluble monomeric proteins; (12723972) -- Annotation transfered from 1pwd 1pwa PROBNOT 1 1 NPS NPS 14730967 14730967 Paper says nothing, PISA says monomer 1pwc PROBNOT 1 1 NPS NPS 15581896 15581896 the Streptomyces R61 and Actinomadura R39 DD-peptidases, are water-soluble monomeric proteins; (12723972) -- Annotation transfered from 1pwd 1pwd PROBNOT 1 1 NPS NPS 15581896 15581896 the Streptomyces R61 and Actinomadura R39 DD-peptidases, are water-soluble monomeric proteins; (12723972) 1pwg PROBNOT 1 1 NPS NPS 15581896 15581896 the Streptomyces R61 and Actinomadura R39 DD-peptidases, are water-soluble monomeric proteins; (12723972) -- Annotation transfered from 1pwd 1pwl NO 1 1 NPS NPS 15146479 15146479 SwissProt and PISA say monomer -- Annotation transfered from 1ads 1pwm NO 1 1 NPS NPS 15146479 15146479 SwissProt and PISA say monomer -- Annotation transfered from 1ads 1pwp_1 PROBNOT 1 1 NPS NPS 14718925 11700563 Paper says nothing about a dimer - an email was sent to the authors -- And its a nature paper!!!! CRAP - automatic transfer from 1jky 1pwp_2 PROBNOT 1 1 NPS NPS 14718925 11700563 Paper says nothing about a dimer - an email was sent to the authors -- And its a nature paper!!!! CRAP - automatic transfer from 1jky 1pwq_1 PROBNOT 1 1 NPS NPS 14718924 11700563 Paper says nothing about a dimer - an email was sent to the authors -- And its a nature paper!!!! CRAP - automatic transfer from 1jky 1pwq_2 PROBNOT 1 1 NPS NPS 14718924 11700563 Paper says nothing about a dimer - an email was sent to the authors -- And its a nature paper!!!! CRAP - automatic transfer from 1jky 1pwt PROBNOT 1 1 NPS NPS 1279434 1279434 -- Annotation transfered from 1neg 1pwu_1 PROBNOT 1 1 NPS NPS 14718924 11700563 Paper says nothing about a dimer - an email was sent to the authors -- And its a nature paper!!!! CRAP - automatic transfer from 1jky 1pwu_2 PROBNOT 1 1 NPS NPS 14718924 11700563 Paper says nothing about a dimer - an email was sent to the authors -- And its a nature paper!!!! CRAP - automatic transfer from 1jky 1pwv_1 PROBNOT 1 1 NPS NPS 14718924 11700563 Paper says nothing about a dimer - an email was sent to the authors -- And its a nature paper!!!! CRAP - automatic transfer from 1jky 1pwv_2 PROBNOT 1 1 NPS NPS 14718924 11700563 Paper says nothing about a dimer - an email was sent to the authors -- And its a nature paper!!!! CRAP - automatic transfer from 1jky 1pww_1 PROBNOT 1 1 NPS NPS 14718924 11700563 Paper says nothing about a dimer - an email was sent to the authors -- And its a nature paper!!!! CRAP - automatic transfer from 1jky 1pww_2 PROBNOT 1 1 NPS NPS 14718924 11700563 Paper says nothing about a dimer - an email was sent to the authors -- And its a nature paper!!!! CRAP - automatic transfer from 1jky 1pwx NO 4 4 D2 D2 14517233 14517233 Interface geometry conserved with 1o5i (29%) -- interesting class to show burst of crosstalk below 30% 1pwy NO 3 3 C3 C3 12914786 12914786 Paper says trimer -- Annotation transfered from 1ula 1pwz NO 4 4 D2 D2 14517233 14517233 Interface geometry conserved with 1o5i (29%) -- interesting class to show burst of crosstalk below 30% -- Annotation transfered from 1pwx 1px0 NO 4 4 D2 D2 14517233 14517233 Interface geometry conserved with 1o5i (29%) -- interesting class to show burst of crosstalk below 30% -- Annotation transfered from 1pwx 1px2 NO 4 4 D2 D2 14688264 14688264 Paper says: An ATP-stabilized tetramer of rSynI-ABC is observed during velocity sedimentation and size-exclusion chromatographic experiments. 1px6 NO 2 2 C2 C2 0 0 -- Annotation transfered from 9gss 1px7 NO 2 2 C2 C2 0 0 -- Annotation transfered from 9gss 1pxa NO 2 2 C2 C2 8312276 8312276 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1pxb NO 2 2 C2 C2 8312276 8312276 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1pxc NO 2 2 C2 C2 8312276 8312276 the enzyme exists mainly as a dimer in solution -- Annotation transfered from 2phh 1pxf NO 2 2 C2 C2 11101501 11101501 Paper says dimer 1pxh PROBNOT 1 1 NPS NPS 12547827 12547827 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1pxi NO 1 1 NPS NPS 12679018 12679018 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1pxj NO 1 1 NPS NPS 12679018 12679018 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1pxk NO 1 1 NPS NPS 12679018 12679018 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1pxl NO 1 1 NPS NPS 12679018 12679018 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1pxm NO 1 1 NPS NPS 15027857 15027857 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1pxn NO 1 1 NPS NPS 15027857 15027857 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1pxo NO 1 1 NPS NPS 15027857 15027857 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1pxp NO 1 1 NPS NPS 15027857 15027857 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1pxr_1 YES 1 3 NPS C3 14659758 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1pxr_2 YES 1 3 NPS C3 14659758 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1pxs_1 YES 1 3 NPS C3 14659758 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1pxs_2 YES 1 3 NPS C3 14659758 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1pxt NO 2 2 C2 C2 7812714 7812714 Paper says dimer -- Annotation transfered from 1afw 1pxx_1 NO 2 2 C2 C2 12925531 10811226 - automatic transfer from 1cvu 1pxx_2 NO 2 2 C2 C2 12925531 10811226 - automatic transfer from 1cvu 1py0 NO 1 1 NPS NPS 15224334 9341204 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 - automatic transfer from 8paz 1py2_1 PROBNOT 1 1 NPS NPS 14664558 0 BU changed since last release and is now corrected - - automaticaly inferred from 3ink 1py2_2 PROBNOT 1 1 NPS NPS 14664558 0 BU changed since last release and is now corrected - - automaticaly inferred from 3ink 1py2_3 PROBNOT 1 1 NPS NPS 14664558 0 BU changed since last release and is now corrected - - automaticaly inferred from 3ink 1py2_4 PROBNOT 1 1 NPS NPS 14664558 0 BU changed since last release and is now corrected - - automaticaly inferred from 3ink 1py5 PROBNOT 1 1 NPS NPS 15177479 15177479 Paper says nothing, PISA says monomer 1py6_1 YES 1 3 NPS C3 14659758 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1py6_2 YES 1 3 NPS C3 14659758 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1py9 NO 2 2 C2 C2 12960396 12960396 Paper says dimer 1pyd YES 2 4 C2 D2 8512926 8512926 Paper says tetramer -- PISA does not find -- Annotation transfered from 1pvd 1pye NO 1 1 NPS NPS 14749470 14749470 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1pyg NO 4 4 D2 D2 1962195 1962195 Paper says: Phosphorylase reconstituted with PLPP is not active, but the modified enzyme exhibits properties the of R-state conformation as detected by high affinity for AMP and aggregation of dimers to tetramers (Withers et al., 1982). -- Annotation transfered from 1abb 1pym NO 4 4 D2 D2 10378273 10378273 Paper and SP say tetramer -- Annotation transfered from 1m1b 1pyn PROBNOT 1 1 NPS NPS 12951078 12951078 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1pyx NO 2 2 C2 C2 14529625 14529625 Paper says dimer detected in solution but the functional significance is unclear (autoinhibition is a possibility) - monomer/dimer equilibrium -- Annotation transfered from 1h8f 1pyy PROBNOT 1 1 NPS NPS 12923202 12923202 -- Annotation transfered from 1pmd 1pza NO 1 1 NPS NPS 8034003 8034003 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 -- Annotation transfered from 8paz 1pzb NO 1 1 NPS NPS 8034003 8034003 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 -- Annotation transfered from 8paz 1pzc NO 1 1 NPS NPS 7635192 8034003 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 -- Annotation transfered from 8paz 1pze NO 4 4 D2 D2 14744130 14744130 Paper says tetramer 1pzf NO 4 4 D2 D2 14744130 14744130 Paper says tetramer -- Annotation transfered from 1pze 1pzg NO 4 4 D2 D2 14744130 14744130 Paper says tetramer -- Annotation transfered from 1pze 1pzh NO 4 4 D2 D2 14744130 14744130 Paper says tetramer -- Annotation transfered from 1pze 1pzl YES 1 2 NPS C2 14982928 14982928 Paper says dimer -- PISA does not find it 1pzm PROBNOT 2 2 C2 C2 17894860 0 No paper but closest structures are dimers and PISA says dimer 1pzo PROBNOT 1 1 NPS NPS 15037085 0 EcoCyc says monomer -- Annotation transfered from 1jwp 1pzp PROBNOT 1 1 NPS NPS 15037085 0 EcoCyc says monomer -- Annotation transfered from 1jwp 1pzs NO 2 2 C2 C2 15155722 15155722 Paper says dimer - apparently the only functional SOD that does not require Zinc. 1pzt PROBNOT 1 1 NPS NPS 12927542 12927542 Paper says nothing, PISA says monomer 1pzv PROBNOT 1 1 NPS NPS 0 0 PAper not found, PISA says monomer -- monomeric state seems consistent across the different homologous proteins. 1pzz_1 PROBNOT 1 1 NPS NPS 15632285 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1pzz_2 PROBNOT 1 1 NPS NPS 15632285 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1q03_1 PROBNOT 1 1 NPS NPS 15632285 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1q03_2 PROBNOT 1 1 NPS NPS 15632285 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1q04_1 PROBNOT 1 1 NPS NPS 15632285 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1q04_2 PROBNOT 1 1 NPS NPS 15632285 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1q0b_1 PROBNOT 1 1 NPS NPS 14672662 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 1q0b_2 PROBNOT 1 1 NPS NPS 14672662 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 1q0c NO 4 4 D2 D2 15028678 15028678 Interface geometry conserved with 1mpy (25%) -- Annotation transfered from 1f1x 1q0e_1 PROBYES 1 2 NPS C2 12906825 1619651 BU changed since last release and is now incorrect - PAper, SP say dimer - automaticaly inferred from 1cob 1q0e_2 PROBYES 1 2 NPS C2 12906825 1619651 BU changed since last release and is now incorrect - PAper, SP say dimer - automaticaly inferred from 1cob 1q0n PROBNOT 1 1 NPS NPS 11080626 11080626 EcoCyc & SP say monomer. -- Annotation transfered from 1eqm 1q0o NO 4 4 D2 D2 15028678 15028678 Interface geometry conserved with 1mpy (25%) -- Annotation transfered from 1f1x 1q14 PROBYES 3 3 C3 C3 14502267 14502267 acetyl-lysine peptide binding induces a trimer-monomer protein transition involving nonconserved Sir2 residues - interesting -- Annotation transfered from 1q17 1q17 PROBYES 3 3 C3 C3 14604530 14604530 acetyl-lysine peptide binding induces a trimer-monomer protein transition involving nonconserved Sir2 residues - interesting 1q1a PROBNOT 1 1 NPS NPS 14604530 14604530 acetyl-lysine peptide binding induces a trimer-monomer protein transition involving nonconserved Sir2 residues - interesting -- Annotation transfered from 1szc 1q1f PROBNOT 1 1 NPS NPS 15162488 15162488 SP says monomer 1q1g NO 6 6 D3 D3 14982926 14982926 Interface geometry conserved with 1vhj 1q1k NO 6 6 D3 D3 14741209 14741209 Paper says hexamer 1q1m PROBNOT 1 1 NPS NPS 13678400 13678400 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1q1n NO 2 2 C2 C2 15289102 15289102 1q1p PROBNOT 1 1 NPS NPS 15071499 15071499 N-terminal processing induces docking of the tryptophan-2 side-chain into a binding pocket on the same molecule. At high concentration, cleavage induces dimerization. 1q1q PROBNOT 1 1 NPS NPS 12923182 12923182 Paper says nothing, PISA says monomer 1q1s PROBNOT 1 1 NPS NPS 12852786 12852786 Paper says: suggesting that both proteins are monomeric under these conditions -- Annotation transfered from 1iq1 1q1t PROBNOT 1 1 NPS NPS 12852786 12852786 Paper says: suggesting that both proteins are monomeric under these conditions -- Annotation transfered from 1iq1 1q1u NO 1 1 NPS NPS 12815063 12815063 In order to prevent disulfide-mediated dimer formation, Cys144 of FHF1b was mutated to alanine (the corresponding residue in all other FHFs). Monomeric FHF1b was expressed in E. coli strain BL21 (DE3) pLysS cells and was purified by heparin affinity, ion exchange, and size exclusion chromatography. 1q1y PROBNOT 1 1 NPS NPS 15382235 15382235 Paper implies monomer - related protein are monomeric and PISA says monomer 1q1z PROBNOT 1 1 NPS NPS 12923182 12923182 Paper says nothing, PISA says monomer -- Annotation transfered from 1q1q 1q20 PROBNOT 1 1 NPS NPS 12923182 12923182 Paper says nothing, PISA says monomer -- Annotation transfered from 1q1q 1q21 PROBYES 2 1 C2 NPS 1899707 1899707 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 1q22 PROBNOT 1 1 NPS NPS 12923182 12923182 Paper says nothing, PISA says monomer -- Annotation transfered from 1q1q 1q24 NO 1 1 NPS NPS 12798691 12798691 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1q2b PROBNOT 1 1 NPS NPS 14568538 14568538 None of the papers speaks about a dimer - a dimer is found using PISA but visual inspection reveals a weak interface. -- Annotation transfered from 6cel 1q2c PROBNOT 1 1 NPS NPS 14536085 14536085 Paper says: Narrow line widths are consistent with gel filtration, chromatographic, and mass spectrometric results that suggest the bromodomain is monomeric in solution. -- Annotation transfered from 1q2d 1q2d PROBNOT 1 1 NPS NPS 14661947 11090279 Paper says: Narrow line widths are consistent with gel filtration, chromatographic, and mass spectrometric results that suggest the bromodomain is monomeric in solution. 1q2e_1 PROBNOT 1 1 NPS NPS 14568538 9466911 None of the papers speaks about a dimer - a dimer is found using PISA but visual inspection reveals a weak interface. - automatic transfer from 6cel 1q2e_2 PROBNOT 1 1 NPS NPS 14568538 9466911 None of the papers speaks about a dimer - a dimer is found using PISA but visual inspection reveals a weak interface. - automatic transfer from 6cel 1q2o NO 2 2 C2 C2 14718923 0 Clear dimer -- Annotation transfered from 1fol 1q2p PROBNOT 1 1 NPS NPS 15588091 15588091 -- Annotation transfered from 1ong 1q2q PROBNOT 1 1 NPS NPS 15588091 15588091 This is a class C beta Lactamase and those are monomeric (12951239) -- Annotation transfered from 1c3b -- Annotation transfered from 1ga0 1q2u YES 1 2 NPS C2 12914946 12914946 Homodimeric -- Annotation transfered from 1ps4 1q2v NO 16 16 D8 D8 14729342 14729342 -- Annotation transfered from 1q3q 1q2x NO 2 2 C2 C2 15272161 0 1q36 PROBNOT 1 1 NPS NPS 13129913 13129913 SP says monomer 1q39 PROBNOT 1 1 NPS NPS 16145054 16145054 Paper says nothing, PISA says monomer and related prots are monomeric (which makes sense). -- Annotation transfered from 1k3w 1q3b PROBNOT 1 1 NPS NPS 16145054 16145054 Paper says nothing, PISA says monomer and related prots are monomeric (which makes sense). -- Annotation transfered from 1k3w 1q3c PROBNOT 1 1 NPS NPS 16145054 16145054 Paper says nothing, PISA says monomer and related prots are monomeric (which makes sense). -- Annotation transfered from 1k3w 1q3d NO 2 2 C2 C2 14529625 14529625 Paper says dimer detected in solution but the functional significance is unclear (autoinhibition is a possibility) - monomer/dimer equilibrium -- Annotation transfered from 1h8f 1q3g_1 PROBYES 4 1 D2 NPS 13129913 10823915 BU changed since last release and is now incorrect - MurA crystallizes from PEG 20000 as a monomeric species. - automaticaly inferred from 1eyn 1q3g_2 PROBYES 4 1 D2 NPS 13129913 10823915 BU changed since last release and is now incorrect - MurA crystallizes from PEG 20000 as a monomeric species. - automaticaly inferred from 1eyn 1q3g_3 PROBYES 4 1 D2 NPS 13129913 10823915 BU changed since last release and is now incorrect - MurA crystallizes from PEG 20000 as a monomeric species. - automaticaly inferred from 1eyn 1q3g_4 PROBYES 4 1 D2 NPS 13129913 10823915 BU changed since last release and is now incorrect - MurA crystallizes from PEG 20000 as a monomeric species. - automaticaly inferred from 1eyn 1q3n PROBNOT 4 4 D2 D2 16023668 11371194 BU changed since last release and is now corrected - - automaticaly inferred from 1g7u 1q3o NO 2 2 C2 C2 12954649 12954649 Paper says: gel filtration profile of the native Shank1 PDZ domain shows the existence of Shank1 PDZ dimers in solution -- Annotation transfered from 1q3p 1q3p NO 2 2 C2 C2 12954649 12954649 Paper says: gel filtration profile of the native Shank1 PDZ domain shows the existence of Shank1 PDZ dimers in solution 1q3q NO 16 16 D8 D8 14729342 14729342 1q3r NO 16 16 D8 D8 14729342 14729342 -- Annotation transfered from 1q3q 1q3s NO 16 16 D8 D8 14729342 14729342 -- Annotation transfered from 1q3q 1q3u YES 4 8 C4 C4 12954782 12954782 BU changed since last release and is now incorrect - -- Annotation transfered from 1kbu 1q3v YES 4 6 C4 C4 12954782 12954782 BU changed since last release and is now incorrect - Paper says tetramer -- Annotation transfered from 1ouq 1q3w NO 2 2 C2 C2 14529625 14529625 Paper says dimer detected in solution but the functional significance is unclear (autoinhibition is a possibility) - monomer/dimer equilibrium -- Annotation transfered from 1h8f 1q40_1 YES 2 1 NS NPS 14504280 14504280 Paper says: Gel-filtration experiments showed that Mtr2 is monomeric in solution (data not shown) as it is in the crystals. 1q40_2 YES 2 1 NS NPS 14504280 14504280 Paper says: Gel-filtration experiments showed that Mtr2 is monomeric in solution (data not shown) as it is in the crystals. 1q41 NO 2 2 C2 C2 14529625 14529625 Paper says dimer detected in solution but the functional significance is unclear (autoinhibition is a possibility) - monomer/dimer equilibrium -- Annotation transfered from 1h8f 1q44 NA 1 1 NPS NPS 15317023 15317023 Paper says nothing and PISA find a dimer with an large interface. 1q4a NO 1 1 NPS NPS 14684834 14684834 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1q4b NO 1 1 NPS NPS 14684834 14684834 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1q4c NO 1 1 NPS NPS 14684834 14684834 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1q4d NO 1 1 NPS NPS 14684834 14684834 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1q4e NO 1 1 NPS NPS 14684834 14684834 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1q4g NO 2 2 C2 C2 14672659 14672659 -- Annotation transfered from 1cqe 1q4j NO 2 2 C2 C2 12972411 12972411 paper says glutathione S-transferases are functional dimers. 1q4l NO 2 2 C2 C2 14529625 14529625 Paper says dimer detected in solution but the functional significance is unclear (autoinhibition is a possibility) - monomer/dimer equilibrium -- Annotation transfered from 1h8f 1q4q_1 PROBNOT 1 1 NPS NPS 14517550 11511363 Gel filtration mentioned but apparently no dimer seen. - automatic transfer from 1jd6 1q4q_10 PROBNOT 1 1 NPS NPS 14517550 11511363 Gel filtration mentioned but apparently no dimer seen. - automatic transfer from 1jd6 1q4q_2 PROBNOT 1 1 NPS NPS 14517550 11511363 Gel filtration mentioned but apparently no dimer seen. - automatic transfer from 1jd6 1q4q_3 PROBNOT 1 1 NPS NPS 14517550 11511363 Gel filtration mentioned but apparently no dimer seen. - automatic transfer from 1jd6 1q4q_4 PROBNOT 1 1 NPS NPS 14517550 11511363 Gel filtration mentioned but apparently no dimer seen. - automatic transfer from 1jd6 1q4q_5 PROBNOT 1 1 NPS NPS 14517550 11511363 Gel filtration mentioned but apparently no dimer seen. - automatic transfer from 1jd6 1q4q_6 PROBNOT 1 1 NPS NPS 14517550 11511363 Gel filtration mentioned but apparently no dimer seen. - automatic transfer from 1jd6 1q4q_7 PROBNOT 1 1 NPS NPS 14517550 11511363 Gel filtration mentioned but apparently no dimer seen. - automatic transfer from 1jd6 1q4q_8 PROBNOT 1 1 NPS NPS 14517550 11511363 Gel filtration mentioned but apparently no dimer seen. - automatic transfer from 1jd6 1q4q_9 PROBNOT 1 1 NPS NPS 14517550 11511363 Gel filtration mentioned but apparently no dimer seen. - automatic transfer from 1jd6 1q4s NO 4 4 D2 D2 12907670 12907670 Paper says tetramer 1q4t NO 4 4 D2 D2 12907670 12907670 Paper says tetramer -- Annotation transfered from 1q4s 1q4u NO 4 4 D2 D2 12907670 12907670 Paper says tetramer -- Annotation transfered from 1q4s 1q4x PROBNOT 1 1 NPS NPS 14673100 14673100 Paper says nothing, related are monomeric and PISA says monomer 1q50 NO 2 2 C2 C2 15206941 15206941 1q54 PROBYES 2 1 C2 NPS 12630859 12630859 Seems to be a monomer - PISA would be wrong -- Annotation transfered from 1nfs 1q57 NO 7 7 NS NS 14636571 14636571 Paper says: The crystallized primase-helicase is a heptamer with a crown-like shape, reflecting an intimate packing of helicase domains into a ring that is topped with loosely arrayed primase domains. 1q5d PROBNOT 1 1 NPS NPS 12933799 12933799 11304120 says P450s are monomeric enzymes 1q5e PROBNOT 1 1 NPS NPS 12933799 12933799 11304120 says P450s are monomeric enzymes -- Annotation transfered from 1q5d 1q5i_1 YES 1 3 NPS C3 14732697 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1q5i_2 YES 1 3 NPS C3 14732697 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1q5j_1 YES 1 3 NPS C3 14732697 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1q5j_2 YES 1 3 NPS C3 14732697 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1q5k NO 2 2 C2 C2 12928438 0 Paper says dimer detected in solution but the functional significance is unclear (autoinhibition is a possibility) - monomer/dimer equilibrium -- Annotation transfered from 1h8f 1q5n NO 4 4 D2 D2 0 0 Interface geometry conserved with 1fur (22%) 1q5p NO 1 1 NPS NPS 12962477 12962477 -- Annotation transfered from 1c9n 1q5t PROBNOT 2 2 C2 C2 15003507 15003507 Can form paralogous dimers so probably relevant 1q5x NO 3 3 C3 C3 14499605 14499605 Interface geometry conserved with 1vi4 (44%) 1q61 NO 1 1 NPS NPS 12798691 12798691 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1q62 NO 1 1 NPS NPS 12798691 12798691 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1q6c PROBNOT 1 1 NPS NPS 14638688 14638688 SP says monomer -- Annotation transfered from 1v3i 1q6d PROBNOT 1 1 NPS NPS 14638688 14638688 SP says monomer -- Annotation transfered from 1v3i 1q6e PROBNOT 1 1 NPS NPS 14638688 14638688 SP says monomer -- Annotation transfered from 1v3i 1q6f PROBNOT 1 1 NPS NPS 14638688 14638688 SP says monomer -- Annotation transfered from 1v3i 1q6g PROBNOT 1 1 NPS NPS 14638688 14638688 SP says monomer -- Annotation transfered from 1v3i 1q6h NO 2 2 C2 C2 14672666 14672666 Paper says dimer - However I am not sure about the domain architecture: there seem to have two domains, and the paper describes two different functions for these domains, but in SCOP only one is described. error? 1q6i NO 2 2 C2 C2 14672666 0 Paper says dimer - However I am not sure about the domain architecture: there seem to have two domains, and the paper describes two different functions for these domains, but in SCOP only one is described. error? -- Annotation transfered from 1q6h 1q6j PROBNOT 1 1 NPS NPS 14516196 14516196 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1q6k NO 1 1 NPS NPS 14684342 14684342 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa -- Annotation transfered from 1atk 1q6l NO 2 2 C2 C2 14567674 14567674 Interface geometry conserved with 1lor -- Annotation transfered from 1q6q 1q6m PROBNOT 1 1 NPS NPS 14516196 14516196 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1q6n_1 PROBNOT 1 1 NPS NPS 14516196 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1q6n_2 PROBNOT 1 1 NPS NPS 14516196 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1q6o NO 2 2 C2 C2 14567674 14567674 Interface geometry conserved with 1lor -- Annotation transfered from 1q6q 1q6p_1 PROBNOT 1 1 NPS NPS 14516196 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1q6p_2 PROBNOT 1 1 NPS NPS 14516196 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1q6q NO 2 2 C2 C2 14567674 14567674 Interface geometry conserved with 1lor 1q6r NO 2 2 C2 C2 14567674 14567674 Interface geometry conserved with 1lor -- Annotation transfered from 1q6q 1q6s_1 PROBNOT 1 1 NPS NPS 14516196 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1q6s_2 PROBNOT 1 1 NPS NPS 14516196 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1q6t_1 PROBNOT 1 1 NPS NPS 14516196 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1q6t_2 PROBNOT 1 1 NPS NPS 14516196 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1q6u NO 2 2 C2 C2 14672666 0 Paper says dimer - However I am not sure about the domain architecture: there seem to have two domains, and the paper describes two different functions for these domains, but in SCOP only one is described. error? -- Annotation transfered from 1q6h 1q6v PROBNOT 1 1 NPS NPS 0 0 SP says monomer 1q6z NO 4 4 D2 D2 0 9665697 Interface geometry conserved with 1ovm (25%) - automatic transfer from 1bfd 1q73 NO 1 1 NPS NPS 14684834 14684834 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1q7a PROBNOT 1 1 NPS NPS 15544328 15544328 SP says monomer -- Annotation transfered from 1tgm 1q7b NO 4 4 D2 D2 15016358 15016358 Swissprot says homotetramer -- Annotation transfered from 1q7c 1q7c NO 4 4 D2 D2 15016358 15016358 Swissprot says homotetramer 1q83 NO 2 2 C2 C2 14757816 0 They explain in the paper why they observe a different crystal form without tetrameric assembly - interesting -- Annotation transfered from 1j07 1q84 NO 2 2 C2 C2 14757816 0 They explain in the paper why they observe a different crystal form without tetrameric assembly - interesting -- Annotation transfered from 1j07 1q8b PROBYES 2 1 NS NPS 0 0 Annotated during the 3D Complex curation 1q8f NO 4 4 D2 D2 15130467 15130467 Interface geometry conserved with 1mas (40%) 1q8m_1 PROBYES 2 1 C2 NPS 14656437 15351648 BU changed since last release and is now incorrect - Paper says: Hence, when taken together, the biophysical and crystallographic evidence presented here, strongly suggest that in solution the globular head of the TREM-1 ectodomain is monomeric. - automaticaly inferred from 1smo 1q8m_2 PROBYES 2 1 C2 NPS 14656437 15351648 BU changed since last release and is now incorrect - Paper says: Hence, when taken together, the biophysical and crystallographic evidence presented here, strongly suggest that in solution the globular head of the TREM-1 ectodomain is monomeric. - automaticaly inferred from 1smo 1q8o NO 2 2 C2 C2 14729339 14729339 Implied in paper that it is a dimer, PISA also says that -- Annotation transfered from 1n3q 1q8p NO 2 2 C2 C2 14729339 14729339 Implied in paper that it is a dimer, PISA also says that -- Annotation transfered from 1n3q 1q8q NO 2 2 C2 C2 14729339 14729339 Implied in paper that it is a dimer, PISA also says that -- Annotation transfered from 1n3q 1q8s NO 2 2 C2 C2 14729339 14729339 Implied in paper that it is a dimer, PISA also says that -- Annotation transfered from 1n3q 1q8t NO 1 1 NPS NPS 14656443 0 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1q8u NO 1 1 NPS NPS 14656443 0 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1q8v NO 2 2 C2 C2 14729339 14729339 Implied in paper that it is a dimer, PISA also says that -- Annotation transfered from 1n3q 1q8w NO 1 1 NPS NPS 14656443 0 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1q91 YES 1 1 NPS NPS 15044615 15044615 PISA is right 1q92 YES 1 1 NPS NPS 15044615 15044615 PISA is right -- Annotation transfered from 1q91 1q95 NO 12 12 D3 D3 15157075 15157075 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1q98 NO 2 2 C2 C2 0 0 Interface geometry conserved with 1psq (45%) 1q9d YES 2 4 C2 D2 14530289 14530289 -- Annotation transfered from 1nv7 1q9i PROBNOT 1 1 NPS NPS 15109257 15109257 SP says monomer -- Annotation transfered from 1qjd 1q9m PROBNOT 4 4 D2 D2 12842049 12842049 the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state -- Annotation transfered from 1oyn 1qa0 PROBNOT 1 1 NPS NPS 10417407 10417407 -- Annotation transfered from 1az8 1qa1 YES 1 3 NPS C3 10543960 10543960 Paper says trimer -- very interesting pet example protein: folding pathway well studied in vitro and in vivo. Does not fold above 40 degrees but once formed, stable up to 80 degrees! Trimer formation seems to be the limiting step. Good pet example 1qa2 YES 1 3 NPS C3 10543960 10543960 Paper says trimer -- Annotation transfered from 1qa1 1qa3 YES 1 3 NPS C3 10543960 10543960 Paper says trimer -- Annotation transfered from 1qa1 1qac NO 2 2 C2 C2 11045631 11045631 Interface conserved down to <30% (1cd8)! -- Annotation transfered from 1lve 1qad NO 1 1 NPS NPS 10525402 10525402 Paper says: Phosphoinositide 3-kinases belonging to this class and which are regulated by growth factor receptor tyrosine kinases, are tightly coupled heterodimers consisting of an 85 kDa regulatory subunit (p85) and a 110 kDa catalytic subunit (p110). So no homo-interaction, plus here only a SH2 domain from the regulatory sub. 1qah YES 2 3 NS C3 0 0 Interface geometry conserved with 1pf5 (30%) 1qai PROBYES 2 1 C2 NPS 10669612 10669612 BU changed since last release and is now incorrect - 1qaj PROBYES 2 1 C2 NPS 10669612 10669612 -- Annotation transfered from 1d0e 1qau PROBNOT 1 1 NPS NPS 10221915 10221915 According to the paper figure, it is a monomer or heteromer 1qax PROBNOT 2 2 C2 C2 10377386 10377386 Paper says dimer although no hard evidence is given. 1qay PROBNOT 2 2 C2 C2 10377386 10377386 Paper says dimer although no hard evidence is given. -- Annotation transfered from 1qax 1qb1 PROBNOT 1 1 NPS NPS 10417407 10417407 -- Annotation transfered from 1az8 1qb4 YES 4 4 NS D2 10481043 10481043 Interface geometry conserved with 1jqo (40%) 1qb6 PROBNOT 1 1 NPS NPS 10417407 10417407 -- Annotation transfered from 1az8 1qb9 PROBNOT 1 1 NPS NPS 10417407 10417407 -- Annotation transfered from 1az8 1qba PROBNOT 1 1 NPS NPS 8673609 8673609 SP and PISA say monomer -- Annotation transfered from 1qbb 1qbb PROBNOT 1 1 NPS NPS 8673609 8673609 SP and PISA say monomer 1qbg_1 PROBYES 1 2 NPS C2 10543876 11587640 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - - automaticaly inferred from 1h66_2 1qbg_2 PROBYES 1 2 NPS C2 10543876 11587640 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - - automaticaly inferred from 1h66_2 1qbg_3 PROBYES 1 2 NPS C2 10543876 11587640 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - - automaticaly inferred from 1h66_2 1qbg_4 PROBYES 1 2 NPS C2 10543876 11587640 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - - automaticaly inferred from 1h66_2 1qbn PROBNOT 1 1 NPS NPS 10417407 10417407 -- Annotation transfered from 1az8 1qbo PROBNOT 1 1 NPS NPS 10417407 10417407 -- Annotation transfered from 1az8 1qbr NO 2 2 C2 C2 9003516 9003516 -- Annotation transfered from 1ajx 1qbs NO 2 2 C2 C2 8784449 8784449 -- Annotation transfered from 1ajx 1qbt NO 2 2 C2 C2 9003516 9003516 -- Annotation transfered from 1ajx 1qbu NO 2 2 C2 C2 9003516 9003516 -- Annotation transfered from 1ajx 1qc5 PROBYES 2 1 NS NPS 10455165 14660600 BU changed since last release and is now incorrect - - automaticaly inferred from 1qcy 1qc6 PROBYES 2 1 C2 NPS 10404224 10404224 Protein was purified by gel filtration and nothing is said about a dimer so it was probably not seen. 1qc7 NA 2 24 C2 NS 10440379 10440379 FliG forms a large ring with apparently 24 subunits (taken from the paper). However it is difficult to know whether it is C24 or D12 symmetry. 1qca PROBNOT 3 3 C3 C3 7500366 7500366 SP says trimer -- PISA very wrong -- Annotation transfered from 3cla 1qcf NO 1 1 NPS NPS 10360180 10360180 The author of 2hck told me it was known to be a monomer 1qcp PROBNOT 1 1 NPS NPS 10531473 10531473 -- Annotation transfered from 1az8 1qcq PROBNOT 1 1 NPS NPS 8268156 8268156 Paper not available - PISA says monomer -- monomeric state seems consistent across the different homologous proteins. 1qcs PROBNOT 1 1 NPS NPS 10445031 10445031 Protein crystalises as a monomer in a non-native state (normally hexamer) 1qcw NO 4 4 C4 C4 10727218 11914072 Paper says tetramer. Note that one domain has been artificially truncated. -- Annotation transfered from 1kbj 1qcy PROBNOT 1 1 NPS NPS 14660600 14660600 1qd0 NO 1 1 NPS NPS 10684599 10684599 Paper says monomeric 1qd2 PROBNOT 1 1 NPS NPS 10737925 10737925 No info, PISA says monomer -- Annotation transfered from 1mrk 1qd9 NO 3 3 C3 C3 10557275 10557275 Interface geometry conserved with 1qah (46%) 1qdc NO 4 4 D2 D2 10506175 10506175 SP says tetramer -- Annotation transfered from 1cjp 1qdd PROBNOT 1 1 NPS NPS 10625646 10625646 Paper implies monomeric 1qde NO 1 1 NPS NPS 10404596 10404596 Paper says: Superdex-75 column (Pharmacia)+ eIF4A eluted at the volume expected for a monomeric protein+ -- Annotation transfered from 1qva 1qdn YES 3 6 C3 D3 10559905 10559905 Paper says: NSF is a hexameric ATPase required for the regulated exocytosis of synaptic vesicles and many other intercompartmental vesicular transport steps in eukaryotic cells 1qdo NO 4 4 D2 D2 10506175 10506175 SP says tetramer -- Annotation transfered from 1cjp 1qdq NO 1 1 NPS NPS 10739956 10739956 SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) -- Annotation transfered from 1ito 1qds NO 2 2 C2 C2 10785370 10785370 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1n55 1qdv NO 4 4 C4 C4 11007484 11007484 Interface geometry conserved with 3kvt (42%) 1qdw_1 NO 4 4 C4 C4 11007484 11007484 Interface geometry conserved with 3kvt (42%) - automatic transfer from 1qdv 1qdw_2 NO 4 4 C4 C4 11007484 11007484 Interface geometry conserved with 3kvt (42%) - automatic transfer from 1qdv 1qe0 NO 2 2 C2 C2 10493797 10493797 Interface geometry conserved with 1h4v (42%) 1qe3 PROBNOT 1 1 NPS NPS 10535917 10535917 SP says monomer -- Annotation transfered from 1c7j 1qe5 NO 3 3 C3 C3 10600382 10600382 Interface conserved with 1v48 (36%) -- Annotation transfered from 1c3x 1qe6_1 PROBNOT 2 2 C2 C2 10707023 1988949 Paper says dimer - but a monomer-dimer equilibrium seems to exist - automatic transfer from 3il8 1qe6_2 PROBNOT 2 2 C2 C2 10707023 1988949 Paper says dimer - but a monomer-dimer equilibrium seems to exist - automatic transfer from 3il8 1qez NO 6 6 D3 D3 10386872 10386872 Interface geometry conserved with 1i40 (52%) 1qf0 PROBNOT 1 1 NPS NPS 10504225 10504225 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1qf1 PROBNOT 1 1 NPS NPS 10504225 10504225 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1qf2 PROBNOT 1 1 NPS NPS 10504225 10504225 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1qf3 NO 4 4 C2 C2 10417405 10417405 Paper says tetramer -- Annotation transfered from 2pel 1qfl NO 4 4 D2 D2 10545327 10545327 Paper says tetramer -- Annotation transfered from 1dm3 1qfo_1 PROBNOT 1 1 NPS NPS 9660955 9660955 Paper doesnt mention a dimer and PISA says monomer - automatic transfer from 1qfp 1qfo_2 PROBNOT 1 1 NPS NPS 9660955 9660955 Paper doesnt mention a dimer and PISA says monomer - automatic transfer from 1qfp 1qfo_3 PROBNOT 1 1 NPS NPS 9660955 9660955 Paper doesnt mention a dimer and PISA says monomer - automatic transfer from 1qfp 1qfp PROBNOT 1 1 NPS NPS 9660955 9660955 Paper doesnt mention a dimer and PISA says monomer 1qg2 YES 1 1 NPS NPS 10356329 10356329 Paper says dimer and PISA finds it 1qg4_1 PROBYES 1 2 NPS C2 10356329 9878368 BU changed since last release and is now incorrect - Paper says dimer - automaticaly inferred from 1byu 1qg4_2 PROBYES 1 2 NPS C2 10356329 9878368 BU changed since last release and is now incorrect - Paper says dimer - automaticaly inferred from 1byu 1qg5 PROBNOT 2 2 C2 C2 11168385 11168385 SP says: Under physiological conditions beta-lactoglobulin exists as an equilibrium mixture of monomeric and dimeric forms -- Annotation transfered from 2blg 1qg6 NO 4 4 D2 D2 10493822 10493822 -- Annotation transfered from 1c14 1qg7 PROBYES 2 1 C2 NPS 10954912 10954912 Chemokines are known to be predominantly in the monomeric form at physiological concentrations, and monomeric analogs are biologically active. Moreover, sedimentation equilibrium and NMR studies of SDF-1 have indicated that this chemokine is a monomer even at high concentrations. -- Annotation transfered from 1a15 1qgf PROBNOT 1 1 NPS NPS 10387042 10387042 -- Annotation transfered from 1c1m 1qgh NO 12 12 Tetr Tetr 10625425 10625425 Interface geometry conserved with 1o9r (25%) 1qgl YES 2 4 C2 D2 -1 0 1qgy NO 1 1 NPS NPS 15789405 15789405 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1qgz NO 1 1 NPS NPS 11342548 11342548 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1qh0 NO 1 1 NPS NPS 11342548 11342548 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1qh6_1 PROBNOT 1 1 NPS NPS 10381409 0 BU changed since last release and is now corrected - Almost no contact! - automaticaly inferred from 1h4h 1qh6_2 PROBNOT 1 1 NPS NPS 10381409 0 BU changed since last release and is now corrected - Almost no contact! - automaticaly inferred from 1h4h 1qh7_1 PROBNOT 1 1 NPS NPS 10381409 0 BU changed since last release and is now corrected - Almost no contact! - automaticaly inferred from 1h4h 1qh7_2 PROBNOT 1 1 NPS NPS 10381409 0 BU changed since last release and is now corrected - Almost no contact! - automaticaly inferred from 1h4h 1qha PROBYES 2 1 C2 NPS 10574795 10574795 SP says monomer -- Annotation transfered from 1hkc 1qhb NO 12 12 Tetr Tetr 10843856 10843856 Paper says: It was suggested to be a homododecamer based on its subunit molecular mass of 64 kDa from SDS-gel electrophoresis, and a total molecular mass from equilibrium centrifugation studies of 740 kDa 1qhc_1 PROBNOT 1 1 NPS NPS 10441122 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1qhc_2 PROBNOT 1 1 NPS NPS 10441122 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1qhe PROBNOT 1 1 NPS NPS 10388575 10388575 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1ftg 1qhf NO 4 4 D2 D2 10531478 10531478 11038361 and SP say tetramer -- Annotation transfered from 4pgm 1qhj NO 3 3 C3 C3 10467143 10467143 SP says trimer -- Annotation transfered from 2brd 1qhm NO 2 2 C2 C2 10425676 10425676 -- Annotation transfered from 3pfl 1qhn NO 4 4 D2 D2 10835366 10835366 The enzyme is dimeric in a sulfate-free solution and tetramerization is induced by ammonium sulfate - interesting -- Annotation transfered from 1qhy 1qho PROBNOT 1 1 NPS NPS 10387084 10387084 SP says monomer 1qhp PROBNOT 1 1 NPS NPS 10387084 10387084 SP says monomer -- Annotation transfered from 1qho 1qhq PROBNOT 1 1 NPS NPS 11178893 11178893 Paper says nothing - PISA says monomer 1qhs NO 4 4 D2 D2 10835366 10835366 The enzyme is dimeric in a sulfate-free solution and tetramerization is induced by ammonium sulfate - interesting -- Annotation transfered from 1qhy 1qhu 1 1 NPS NPS 10504726 10504726 BU changed since last release and is now corrected - From the structure it looks like a monomer - automaticaly inferred from 1qjs 1qhx NO 4 4 D2 D2 10835366 10835366 The enzyme is dimeric in a sulfate-free solution and tetramerization is induced by ammonium sulfate - interesting -- Annotation transfered from 1qhy 1qhy NO 4 4 D2 D2 10835366 10835366 The enzyme is dimeric in a sulfate-free solution and tetramerization is induced by ammonium sulfate - interesting 1qi1 NO 4 4 D2 D2 10864505 10864505 Interface geometry conserved with 1uxr (35%) -- Annotation transfered from 1qi6 1qi3 PROBNOT 1 1 NPS NPS 10556241 10556241 SP says monomer -- Annotation transfered from 1gcy 1qi4 PROBNOT 1 1 NPS NPS 10556241 10556241 SP says monomer -- Annotation transfered from 1gcy 1qi5 PROBNOT 1 1 NPS NPS 10556241 10556241 SP says monomer -- Annotation transfered from 1gcy 1qi6 NO 4 4 D2 D2 10864505 10864505 Interface geometry conserved with 1uxr (35%) 1qi7 PROBNOT 1 1 NPS NPS 10745075 10745075 1qi9 NO 2 2 C2 C2 10543953 10543953 Paper says dimer 1qia_1 PROBNOT 1 1 NPS NPS 10422833 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1qia_2 PROBNOT 1 1 NPS NPS 10422833 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1qia_3 PROBNOT 1 1 NPS NPS 10422833 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1qia_4 PROBNOT 1 1 NPS NPS 10422833 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1qic_1 PROBNOT 1 1 NPS NPS 10422833 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1qic_2 PROBNOT 1 1 NPS NPS 10422833 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1qic_3 PROBNOT 1 1 NPS NPS 10422833 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1qic_4 PROBNOT 1 1 NPS NPS 10422833 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 1qid PROBNOT 2 2 C2 C2 10639129 10639129 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. -- Annotation transfered from 1vot 1qie PROBNOT 2 2 C2 C2 10639129 10639129 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. -- Annotation transfered from 1vot 1qif PROBNOT 2 2 C2 C2 10639129 10639129 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. -- Annotation transfered from 1vot 1qig PROBNOT 2 2 C2 C2 10639129 10639129 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. -- Annotation transfered from 1vot 1qih PROBNOT 1 1 NPS NPS 10639129 10639129 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1qii PROBNOT 2 2 C2 C2 10639129 10639129 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. -- Annotation transfered from 1vot 1qij PROBNOT 2 2 C2 C2 10639129 10639129 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. -- Annotation transfered from 1vot 1qik PROBNOT 2 2 C2 C2 10639129 10639129 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. -- Annotation transfered from 1vot 1qim PROBNOT 2 2 C2 C2 10639129 10639129 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. -- Annotation transfered from 1vot 1qin NO 2 2 C2 C2 10521255 10521255 Interface geometry conserved with 1kll (28%) -- interesting: only case I know where two domain swapped proteins diverge and stay swapped. 1qio NO 1 1 NPS NPS 10639129 10639129 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1qip_1 NO 2 2 C2 C2 10521255 10521255 Interface geometry conserved with 1kll (28%) -- interesting: only case I know where two domain swapped proteins diverge and stay swapped. - automatic transfer from 1qin 1qip_2 NO 2 2 C2 C2 10521255 10521255 Interface geometry conserved with 1kll (28%) -- interesting: only case I know where two domain swapped proteins diverge and stay swapped. - automatic transfer from 1qin 1qiq PROBNOT 1 1 NPS NPS 10537113 10537113 No info was found, PISA says monomer. I also think it should be. -- Annotation transfered from 1uzw 1qir NO 2 2 C2 C2 10708649 10708649 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1qis NO 2 2 C2 C2 10708649 10708649 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1qit NO 2 2 C2 C2 10708649 10708649 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1qiv PROBNOT 1 1 NPS NPS 10731425 10731425 -- Annotation transfered from 3cln 1qiw_1 PROBNOT 1 1 NPS NPS 10731425 3145979 - automatic transfer from 3cln 1qiw_2 PROBNOT 1 1 NPS NPS 10731425 3145979 - automatic transfer from 3cln 1qix PROBNOT 1 1 NPS NPS 9187653 9187653 -- Annotation transfered from 1c1m 1qj3 NO 2 2 C2 C2 10452893 10452893 Paper says dimer -- Annotation transfered from 1mly 1qj4 NO 2 2 C2 C2 10494852 10494852 PISA, SP, paper and I say homodimer -- Annotation transfered from 1sc9 1qj5 NO 2 2 C2 C2 10452893 10452893 Paper says dimer -- Annotation transfered from 1mly 1qj8 YES 3 1 C3 NPS 10545325 10545325 Because it is in the membranne, it cannot possibly adopt the trimeric configuration seen in the crystal 1qj9 YES 6 1 D3 NPS 10545325 10545325 Because it is in the membranne, it cannot possibly adopt the hexameric configuration seen in the crystal 1qja NO 2 2 C2 C2 10488331 10488331 14-3-3c forms the canonical dimer found in mammalian 14-3-3 proteins -- Annotation transfered from 1qjb 1qjb NO 2 2 C2 C2 10488331 10488331 14-3-3c forms the canonical dimer found in mammalian 14-3-3 proteins 1qjc PROBNOT 6 6 D3 D3 11812124 10205156 BU changed since last release and is now corrected - This paper (which does not correpond to this particular structure) says it is a hexamer 1qjd PROBNOT 1 1 NPS NPS 10581550 10581550 SP says monomer 1qje PROBNOT 1 1 NPS NPS 10537113 10537113 No info was found, PISA says monomer. I also think it should be. -- Annotation transfered from 1uzw 1qjf PROBNOT 1 1 NPS NPS 10537113 10537113 No info was found, PISA says monomer. I also think it should be. -- Annotation transfered from 1uzw 1qjg_1 PROBNOT 2 2 C2 C2 10551849 9369474 - automatic transfer from 8cho 1qjg_2 PROBNOT 2 2 C2 C2 10551849 9369474 - automatic transfer from 8cho 1qjg_3 PROBNOT 2 2 C2 C2 10551849 9369474 - automatic transfer from 8cho 1qjh NA 2 2 C2 C2 10944185 10944185 They show a tetrameric assembly in the paper but crosslinking exp yields smears, showing random oligomerization. -- Very strange protein ... nonetheless interesting 1qjs PROBYES 2 1 NS NPS 10504726 10504726 From the structure it looks like a monomer 1qjw_1 PROBNOT 1 1 NPS NPS 10508787 12188666 BU changed since last release and is now corrected - Paper implies monomer - PISA also says monomer - automatic transfer from 1hgw_2 1qjw_2 PROBNOT 1 1 NPS NPS 10508787 12188666 BU changed since last release and is now corrected - Paper implies monomer - PISA also says monomer - automatic transfer from 1hgw_2 1qk0_1 PROBNOT 1 1 NPS NPS 10508787 12188666 BU changed since last release and is now corrected - Paper implies monomer - PISA also says monomer - automatic transfer from 1hgw_2 1qk0_2 PROBNOT 1 1 NPS NPS 10508787 12188666 BU changed since last release and is now corrected - Paper implies monomer - PISA also says monomer - automatic transfer from 1hgw_2 1qk1 NO 8 8 D4 D4 10737943 10737943 Interface geometry conserved with 1crk (84%) 1qk2_1 PROBNOT 1 1 NPS NPS 10508787 12188666 BU changed since last release and is now corrected - Paper implies monomer - PISA also says monomer - automatic transfer from 1hgw_2 1qk2_2 PROBNOT 1 1 NPS NPS 10508787 12188666 BU changed since last release and is now corrected - Paper implies monomer - PISA also says monomer - automatic transfer from 1hgw_2 1qk3 NO 4 4 D2 D2 10545170 10545170 Teramer, interface conserved down to 40% (1hmp) 1qk4 NO 4 4 D2 D2 10545170 10545170 Teramer, interface conserved down to 40% (1hmp) -- Annotation transfered from 1qk3 1qk5 NO 4 4 D2 D2 10545171 10545171 Teramer, interface conserved down to 40% (1hmp) -- Annotation transfered from 1qk3 1qk8 PROBNOT 1 1 NPS NPS 10464297 10464297 Paper says that protein is in an oxidized state (no S-S). -- Annotation transfered from 1ezk 1qkd NA 2 2 C2 C2 9757111 9757111 All papers are useless impossible to find an answer %$@~# 1qke NA 1 1 NPS NPS 9757111 9757111 All papers are useless impossible to find an answer %$@~# -- Annotation transfered from 5ebx 1qkj PROBNOT 1 1 NPS NPS 10497034 10497034 SP says monomer -- Annotation transfered from 1bgt 1qkk NO 2 2 C2 C2 11344129 11344129 Paper says dimer 1qkm PROBNOT 2 2 C2 C2 10469641 0 1qkn PROBNOT 2 2 C2 C2 10469641 10469641 -- Annotation transfered from 1qkm 1qko NO 3 3 C3 C3 10548112 10548112 SP says trimer -- Annotation transfered from 2brd 1qkp NO 3 3 C3 C3 10548112 10548112 SP says trimer -- Annotation transfered from 2brd 1qkq YES 2 1 C2 NPS 10563827 10563827 BU changed since last release and is now incorrect - Forms crystals in vivo! -- Annotation transfered from 1g86 1qkr PROBYES 2 1 NS NPS 10612396 10612396 Paper says: The second half of H4 presents the most hydrophobic exposed surface of any helix in the bundle; in both crystal forms, this surface forms part of a crystallographic dimer interaction. It includes I997 and V1001, which are fully exposed to solvent, a cluster of exposed threonines (T990, T993, T1000, and T1004), and only one charged residue, K996. This region has been implicated in binding paxillin 1qks NO 2 2 C2 C2 7736589 7736589 Homodimer -- Annotation transfered from 1h9y 1qkt NO 2 2 C2 C2 11278577 0 paper says dimer -- Annotation transfered from 1err 1qku_1 NO 2 2 C2 C2 11278577 9338790 paper says dimer - automatic transfer from 1err 1qku_2 NO 2 2 C2 C2 11278577 9338790 paper says dimer - automatic transfer from 1err 1qkw PROBNOT 1 1 NPS NPS 11206053 0 -- Annotation transfered from 1neg 1qkx PROBNOT 1 1 NPS NPS 11206053 0 -- Annotation transfered from 1neg 1ql3_1 PROBYES 2 1 NS NPS 10623555 10623555 1ql3_2 PROBYES 2 1 NS NPS 10623555 10623555 - automatic transfer from 1ql3_1 1ql4_1 PROBNOT 1 1 NPS NPS 10623555 10623555 BU changed since last release and is now corrected - - automaticaly inferred from 1ql3_1 1ql4_2 PROBNOT 1 1 NPS NPS 10623555 10623555 BU changed since last release and is now corrected - - automaticaly inferred from 1ql3_1 1ql4_3 PROBNOT 1 1 NPS NPS 10623555 10623555 BU changed since last release and is now corrected - - automaticaly inferred from 1ql3_1 1ql4_4 PROBNOT 1 1 NPS NPS 10623555 10623555 BU changed since last release and is now corrected - - automaticaly inferred from 1ql3_1 1ql6 PROBYES 1 2 NPS C2 10545198 7663944 Paper says it is probably a dimer - PISA is wrong here (overlaping structures) - note that this kinase contains 4 copies of alpha,beta,gamma,delta! - interesting -- Annotation transfered from 2phk 1ql7 PROBNOT 1 1 NPS NPS 11921406 0 -- Annotation transfered from 1az8 1ql8 PROBNOT 1 1 NPS NPS 11921406 0 -- Annotation transfered from 1az8 1ql9 PROBYES 2 1 C2 NPS 12527302 0 BU changed since last release and is now incorrect - Trypsin is monomeric -- Annotation transfered from 2trm 1qlh PROBNOT 2 2 C2 C2 10529241 9132002 BU changed since last release and is now corrected - - automaticaly inferred from 1lde 1qlj YES 1 2 NPS C2 10529241 10529241 -- Annotation transfered from 7adh 1qll NO 2 1 C2 NPS 11141053 0 Paper says they are dimers - SP says monomer but is apparently wrong? - paper is good review of QS state of Lys49 PLA2 - intetesting -- Annotation transfered from 1pa0 1qlp PROBNOT 1 1 NPS NPS 0 0 Paper says nothing, forms a heterodimer with an apparent 1:1 ratio (1oph) and PISA says monomer -- Annotation transfered from 1oo8 1qlq NO 1 1 NPS NPS 10653700 0 10731422 says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium - pH induced oligomerization -- Annotation transfered from 1k6u 1qls NO 2 2 C2 C2 10673436 10673436 Paper says dimer 1qlt PROBYES 2 8 C2 D4 10585424 10585424 Paper says: Analytical gel filtration experiments showed that the His422 mutants are mainly in the octameric form with a small portion being present as a dimer. - dimer octamer equilibrium 1qlu PROBYES 2 8 C2 D4 10585424 10585424 Paper says: Analytical gel filtration experiments showed that the His422 mutants are mainly in the octameric form with a small portion being present as a dimer. - dimer octamer equilibrium -- Annotation transfered from 1qlt 1qlv NO 2 2 C2 C2 0 0 1qm4 YES 4 4 C2 D2 10873471 10873471 The tetramer presented in this biological unit is not the tetramer described in the primary citation. From the primary citation An asymmetric unit contains a tight dimer related by a local 2-fold axis. Crystallographic diad axis generates the active tetramer that, in turn, presents pseudo 222 symmetry. The overall structure of the tetramer is the same as that found in c-MAT, but the arrangement of the subunits is slightly different . Note the structure of c-MAT (PDB entry 1fug) shows the same quaternary structure as given in the paper (D2). 1qm5 NO 2 2 C2 C2 10469642 10469642 -- Annotation transfered from 2ecp 1qm6_1 PROBNOT 1 1 NPS NPS 10610794 9699639 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - the molecule is active as a monomer - automaticaly inferred from 1gyg_1 1qm6_2 PROBNOT 1 1 NPS NPS 10610794 9699639 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - the molecule is active as a monomer - automaticaly inferred from 1gyg_1 1qm7 NA 2 2 C2 C2 10686100 10686100 Ask the persons who work with it 1qm8 NO 3 3 C3 C3 0 0 SP says trimer -- Annotation transfered from 2brd 1qma YES 4 2 D2 C2 10543952 10543952 Paper says dimer 1qmd_1 PROBNOT 1 1 NPS NPS 10610794 9699639 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - the molecule is active as a monomer - automaticaly inferred from 1gyg_1 1qmd_2 PROBNOT 1 1 NPS NPS 10610794 9699639 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - the molecule is active as a monomer - automaticaly inferred from 1gyg_1 1qme PROBYES 2 1 C2 NPS 10860753 10860753 Paper says nothin, PISA says monomer 1qmf PROBYES 2 1 C2 NPS 10860753 10860753 BU changed since last release and is now incorrect - -- Annotation transfered from 1pmd 1qmj NO 2 2 C2 C2 10610778 10610778 Paper says dimer 1qml NO 8 8 D4 D4 10739915 10739915 Paper says octamer 1qmn PROBNOT 1 1 NPS NPS 10618372 10618372 Paper does not speak about a dimer. The protein may aggregate and cause diseases but that implies a strand exchange not seen here so it is likely to be a monomer in that form. PISA says monomer too 1qmp YES 4 1 NS NPS 10556024 10556024 BU changed since last release and is now incorrect - Clearly the structure has a problem. - paper says it dimerizes upon phosphorilation in solution - interesting 1qmq PROBNOT 1 1 NPS NPS 10557259 10557259 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1qmr PROBNOT 2 2 C2 C2 15470071 0 Abs detected, besides a Bet v 1 monomer of 17 kDa, a dimer of 34 kDa. In dynamic light scattering, Bet v 1 appeared as dimers and even multimers, but a single condition could be defined where it behaved exclusively monomerically - monomer dimer equilibrium - interesting -- Annotation transfered from 1bv1 1qmt NO 1 1 NPS NPS 10606511 10606511 -- Annotation transfered from 1h1h 1qmu PROBYES 3 1 C3 NPS 10545093 10545093 The paper implies that it is a monomer 1qmv NO 10 10 D5 D5 10873855 10873855 Interface geometry conseved with 1e2y (57%) 1qng PROBNOT 1 1 NPS NPS 10756109 10756109 BU changed since last release and is now corrected - - automaticaly inferred from 1qnh 1qnh PROBYES 2 1 NS NPS 10756109 10756109 1qnj PROBNOT 1 1 NPS NPS 10739939 10739939 -- Annotation transfered from 1c1m 1qnl PROBYES 2 1 C2 NPS 10708652 10708652 No dimer mentioned in the paper, like E coli, I assume that it is a big complex and that protein is present in one copy only. Plus PISA says monomer 1qnm NO 4 4 D2 D2 9537988 9537988 Paper says tetramer -- Annotation transfered from 1n0j 1qnn YES 4 2 C2 C2 10848964 10848964 Paper says dimer: Each pair of subunits forms a compact dimer, but not a tetramer. 1qnv NO 8 8 D4 D4 10739915 10739915 Paper says octamer -- Annotation transfered from 1qml 1qnw NO 4 4 D2 D2 10966800 0 1qny NO 4 4 D2 D2 10771422 0 SP says tetramer -- Annotation transfered from 1cjp 1qo2 PROBYES 2 1 C2 NPS 10968789 10968789 The HisH and HisF proteins form a stable 1 : 1 dimeric complex that constitutes the IGP synthase holoenzyme. 1qo8 NO 2 2 C2 C2 10581549 10581549 Paper says dimer 1qo9 YES 1 2 NPS C2 10892800 10892800 Paper SP and PISA say dimer. (disulfide bridged!) 1qoa_1 PROBNOT 1 1 NPS NPS 9398238 9287153 Paper does not mention oligomer - similar proteins are monomeric - automatic transfer from 1j7c 1qoa_2 PROBNOT 1 1 NPS NPS 9398238 9287153 Paper does not mention oligomer - similar proteins are monomeric - automatic transfer from 1j7c 1qob_1 PROBNOT 1 1 NPS NPS 9287153 9287153 Paper does not mention oligomer - similar proteins are monomeric - automatic transfer from 1j7c 1qob_2 PROBNOT 1 1 NPS NPS 9287153 9287153 Paper does not mention oligomer - similar proteins are monomeric - automatic transfer from 1j7c 1qof_1 PROBNOT 1 1 NPS NPS 9287153 9287153 Paper does not mention oligomer - similar proteins are monomeric - automatic transfer from 1j7c 1qof_2 PROBNOT 1 1 NPS NPS 9287153 9287153 Paper does not mention oligomer - similar proteins are monomeric - automatic transfer from 1j7c 1qog_1 PROBNOT 1 1 NPS NPS 9287153 9287153 Paper does not mention oligomer - similar proteins are monomeric - automatic transfer from 1j7c 1qog_2 PROBNOT 1 1 NPS NPS 9287153 9287153 Paper does not mention oligomer - similar proteins are monomeric - automatic transfer from 1j7c 1qok PROBNOT 1 1 NPS NPS 10677374 10677374 1qom YES 2 2 C2 C2 10562539 10562539 Wrong reconstruction -- Annotation transfered from 1dwv 1qon YES 1 2 NPS C2 10892800 10892800 Paper SP and PISA say dimer. (disulfide bridged!) -- Annotation transfered from 1qo9 1qoo NO 4 4 D2 D2 10966800 10966800 -- Annotation transfered from 1qnw 1qop NO 4 4 C2 C2 10600108 10600108 Paper says a2b2 -- Annotation transfered from 2wsy 1qoq YES 2 4 NPS C2 10600108 10600108 BU changed since last release and is now incorrect - Paper says a2b2 -- Annotation transfered from 2wsy 1qor NO 2 2 C2 C2 7602590 7602590 Interface geometry conserved with 1v3v (24%) 1qos NO 4 4 D2 D2 10966800 10966800 -- Annotation transfered from 1qnw 1qot NO 4 4 D2 D2 10966800 10966800 -- Annotation transfered from 1qnw 1qou PROBYES 2 1 C2 NPS 10764580 10764580 Paper does not show evidence for dimerization and says: formation of the CEN dimer observed within the crystal structure blocks access to the putative phosphate-binding site (see later), again suggesting the observed dimer may not be functionally relevant. 1qoz PROBYES 2 1 NS NPS 9761918 9761918 The asymmetric unit contains two molecules. 1qp1 YES 3 2 NS C2 9990143 9990143 1qp8 PROBNOT 2 2 C2 C2 0 0 Interface geometry conserved with 2nac, but closer homologs are hexameric -- interesting evolutionary case 1qp9_1 PROBNOT 2 2 NS NS 11024163 9886294 Paper says: The structure reveals that HAP1 is bound in a dramatically asymmetric manner to the DNA target. - automatic transfer from 1hwt_1 1qp9_2 PROBNOT 2 2 NS NS 11024163 9886294 Paper says: The structure reveals that HAP1 is bound in a dramatically asymmetric manner to the DNA target. - automatic transfer from 1hwt_1 1qpa PROBYES 2 1 C2 NPS 10024453 10024453 Paper does not speak about dimer - PISa says monomer and indeed the interface looks like a crystal contact. 1qpb YES 2 4 C2 D2 10651824 10651824 Paper says tetramer -- PISA does not find -- Annotation transfered from 1pvd 1qpc PROBNOT 1 1 NPS NPS 10404594 10404594 1qpd PROBNOT 1 1 NPS NPS 10404594 10404594 -- Annotation transfered from 1qpc 1qpe PROBNOT 1 1 NPS NPS 10404594 10404594 -- Annotation transfered from 1qpc 1qpf YES 2 1 C2 NPS 10425089 10425089 Normally monomeric in solution - But very interesting: one mutation (F36M) transforms it into an inducible dimer. Isnt that so interesting? It thus also shows that it can be very simple to form a heterointerfaces, and that a high proportion of supposedly errors in the BU can reflect a potential high affinity (given that 1/2 mutations are introduced) - very nice example! -- Annotation transfered from 2fke 1qpj PROBNOT 1 1 NPS NPS 10404594 10404594 -- Annotation transfered from 1qpc 1qpk PROBNOT 1 1 NPS NPS 10556241 10556241 SP says monomer -- Annotation transfered from 1gcy 1qpl YES 2 1 NS NPS 10425089 10425089 1qpp PROBNOT 2 2 C2 C2 10393968 10393968 Paper proposes that the dimerization acts as a capping of the interaction surface. It exists in a monomer-dimer equilibrium 1qpx PROBNOT 2 2 C2 C2 10393968 10393968 Paper proposes that the dimerization acts as a capping of the interaction surface. It exists in a monomer-dimer equilibrium -- Annotation transfered from 1qpp 1qq0 NO 3 3 C3 C3 10924115 10924115 PAper says: The active form of the enzyme is a trimer with three zinc-containing active sites -- Annotation transfered from 1thj 1qq1 NO 3 3 C3 C3 10737931 10737931 Paper says trimer -- Annotation transfered from 1tyw 1qq2 NO 2 2 C2 C2 10535922 10535922 Interface geometry conserved with 1e2y (59%) 1qq4 NO 1 1 NPS NPS 0 0 9846867 says monomer -- Annotation transfered from 1p05 1qq9 PROBNOT 1 1 NPS NPS 10771423 10771423 SwissProt says monomer -- Annotation transfered from 1f2o 1qqf PROBYES 2 1 C2 NPS 10825534 10825534 The truncation at the N-terminus of C3d leads to the exposure of a surface of the molecule that favours dimerisation -- interesting case false positive - for a review for example. 1qqh NA 2 1 C2 NPS 10356398 10356398 Paper says: The E2 DBD dimerizes to form a beta barrel with flanking recognition helices positioned in the major grooves of the DNA binding site - However, I suspect that the dimer shown in the crystal structure is wrong (i) it is not discussed in the paper and (ii) it is different from 1dto. Maybe the missing N-ter is too long. 1qql PROBNOT 1 1 NPS NPS 11724555 11724555 No info in paper, PISA says monomer 1qqq YES 1 2 NPS C2 10648646 10648646 Clear dimer 1qqs YES 2 1 NS NPS 10684642 10684642 Neutrophil gelatinase associated lipocalin (NGAL), a member of the lipocalin family, is released from neutrophil granules as a 25 kDa monomer, a 46 kDa disulfide-linked homodimer, and a disulfide-linked heterodimer with gelatinase B (matrix metalloproteinase 9) - this one is not linked by a S-S bond. 1qqt PROBNOT 1 1 NPS NPS 10600385 10600385 Paper says: Crystals of a monomeric fragment of Escherichia coli methionyl-tRNA synthetase (551 N-terminal residues) have been used to determine the 3D-structure of the free enzyme -- Annotation transfered from 1p7p 1qqu PROBNOT 1 1 NPS NPS 10561533 10561533 1qqw NO 4 4 D2 D2 10666617 10666617 Interface geometry conserved with 1mqf (52% id) -- Annotation transfered from 1dgg 1qqy NO 1 1 NPS NPS 10727216 10727216 1qr2 NO 2 2 C2 C2 10433694 10433694 1qr3 PROBNOT 1 1 NPS NPS 10738204 10738204 -- Annotation transfered from 1c1m 1qr7 NO 4 4 D2 D2 10425687 10425687 Interface geometry similar to 1oab (57%) 1qra NO 1 1 NPS NPS 10574788 10574788 Ras proteins are monomeric G proteins -- Annotation transfered from 1ctq 1qrb NO 3 3 C3 C3 10737931 10737931 Paper says trimer -- Annotation transfered from 1tyw 1qrc NO 3 3 C3 C3 10737931 10737931 Paper says trimer -- Annotation transfered from 1tyw 1qrd YES 2 2 C2 C2 7568029 7568029 Wrong reconstruction - PISA did it well. 1qre NO 3 3 C3 C3 10924115 10924115 PAper says: The active form of the enzyme is a trimer with three zinc-containing active sites -- Annotation transfered from 1thj 1qrf NO 3 3 C3 C3 10924115 10924115 PAper says: The active form of the enzyme is a trimer with three zinc-containing active sites -- Annotation transfered from 1thj 1qrg NO 3 3 C3 C3 10924115 10924115 PAper says: The active form of the enzyme is a trimer with three zinc-containing active sites -- Annotation transfered from 1thj 1qrk NO 2 2 C2 C2 9988734 9988734 Paper says dimer -- but wrong reconstruction, PISa get the good interface but makes a tetramer -- Annotation transfered from 1ggt 1qrl NO 3 3 C3 C3 10924115 10924115 PAper says: The active form of the enzyme is a trimer with three zinc-containing active sites -- Annotation transfered from 1thj 1qrm NO 3 3 C3 C3 10924115 10924115 PAper says: The active form of the enzyme is a trimer with three zinc-containing active sites -- Annotation transfered from 1thj 1qrp PROBNOT 1 1 NPS NPS 10713513 10713513 None of the associated paper speaks about oligomeric state - PISA says monomer and related proteins are monomeric -- Annotation transfered from 1psn 1qrq NO 4 4 C4 C4 10399921 10399921 1qrr NO 2 2 C2 C2 10557279 10557279 Paper says dimer 1qrw NO 1 1 NPS NPS 0 0 9846867 says monomer -- Annotation transfered from 1p05 1qrx NO 1 1 NPS NPS 0 0 9846867 says monomer -- Annotation transfered from 1p05 1qrz PROBYES 4 1 NS NPS 10460175 10460175 Paper implies monomer although no clear evidence is given 1qs4_1 PROBNOT 2 2 C2 C2 10557269 9735293 BU changed since last release and is now corrected - - automaticaly inferred from 1bl3 1qs4_2 PROBNOT 2 2 C2 C2 10557269 9735293 BU changed since last release and is now corrected - - automaticaly inferred from 1bl3 1qs5 NO 1 1 NPS NPS 10623513 10623513 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1qs9 NO 1 1 NPS NPS 10623513 10623513 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1qsb NO 1 1 NPS NPS 10623513 10623513 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1qsc NO 3 3 C3 C3 10411888 10411888 Paper says trimer - interface conserved with 1kzz (55%) -- Annotation transfered from 1czy 1qsg_1 NO 4 4 D2 D2 10398587 10595560 - automatic transfer from 1c14 1qsg_2 NO 4 4 D2 D2 10398587 10595560 - automatic transfer from 1c14 1qsj_1 PROBYES 2 1 C2 NPS 10825534 10825534 The truncation at the N-terminus of C3d leads to the exposure of a surface of the molecule that favours dimerisation -- interesting case false positive - for a review for example. - automatic transfer from 1qqf 1qsj_2 PROBYES 2 1 C2 NPS 10825534 10825534 The truncation at the N-terminus of C3d leads to the exposure of a surface of the molecule that favours dimerisation -- interesting case false positive - for a review for example. - automatic transfer from 1qqf 1qsm NO 4 4 D2 D2 10600387 10600387 Paper says tetramer - Here we show that Hpa2 forms a stable dimer in solution and that in the presence of the cofactor AcCoA two dimers associate to form a tetramer - ligand induced tetramerization -- Annotation transfered from 1qso 1qsn PROBNOT 1 1 NPS NPS 10485713 10485713 Paper says: Narrow line widths are consistent with gel filtration, chromatographic, and mass spectrometric results that suggest the bromodomain is monomeric in solution. -- Annotation transfered from 1q2d 1qso NO 4 4 D2 D2 10600387 10600387 Paper says tetramer - Here we show that Hpa2 forms a stable dimer in solution and that in the presence of the cofactor AcCoA two dimers associate to form a tetramer - ligand induced tetramerization 1qsq NO 1 1 NPS NPS 10545167 10545167 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1qsr PROBNOT 1 1 NPS NPS 10485713 10485713 Paper says: Narrow line widths are consistent with gel filtration, chromatographic, and mass spectrometric results that suggest the bromodomain is monomeric in solution. -- Annotation transfered from 1q2d 1qst PROBNOT 1 1 NPS NPS 10485713 10485713 Paper says: Narrow line widths are consistent with gel filtration, chromatographic, and mass spectrometric results that suggest the bromodomain is monomeric in solution. -- Annotation transfered from 1q2d 1qsw_1 YES 1 2 NPS NPS 11340658 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 1qsw_2 YES 1 2 NPS NPS 11340658 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 1qsw_3 YES 1 2 NPS NPS 11340658 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 1qsw_4 YES 1 2 NPS NPS 11340658 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 1qt1 NO 4 4 D2 D2 10666592 10666592 -- Annotation transfered from 1clk 1qt3 NO 1 1 NPS NPS 10430876 10430876 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1qt4 NO 1 1 NPS NPS 10430876 10430876 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1qt5 NO 1 1 NPS NPS 10430876 10430876 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1qt6 NO 1 1 NPS NPS 10430876 10430876 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1qt7 NO 1 1 NPS NPS 10430876 10430876 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1qt8 NO 1 1 NPS NPS 10430876 10430876 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1qt9 PROBNOT 1 1 NPS NPS 10625442 10625442 Paper does not mention oligomer - similar proteins are monomeric -- Annotation transfered from 1j7c 1qtb NO 1 1 NPS NPS 10623513 10623513 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1qtc NO 1 1 NPS NPS 10623513 10623513 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1qtd NO 1 1 NPS NPS 10623513 10623513 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1qth_1 NO 1 1 NPS NPS 10623513 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1qth_2 NO 1 1 NPS NPS 10623513 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1qti PROBNOT 2 2 NS NS 11119642 11119642 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. -- Annotation transfered from 1som 1qtk NO 1 1 NPS NPS 9443341 9443341 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1qtr PROBNOT 1 1 NPS NPS 10467172 10467172 Interface geometry sort of conserved with 1ivy (<30% id) 1qtv NO 1 1 NPS NPS 10430876 10430876 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1qtz NO 1 1 NPS NPS 10430876 10430876 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1qu9 NO 3 3 C3 C3 10595546 10595546 Interface geometry conserved with 1qah (47%) 1qud NO 1 1 NPS NPS 10512706 10512706 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1que NO 1 1 NPS NPS 8890910 8890910 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) 1quf NO 1 1 NPS NPS 8890910 8890910 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) -- Annotation transfered from 1que 1qug NO 1 1 NPS NPS 10512706 10512706 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1quh NO 1 1 NPS NPS 10512706 10512706 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1quo NO 1 1 NPS NPS 10512706 10512706 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1qup PROBNOT 2 2 C2 C2 10426947 10426947 Interestingly, the homodimer site is also a site for heterodimer formation (in 1jk9). Paper 10446130 suggests that the homodimer is biological. They says: We show here that yCCS homodimer formation in vitro is stimulated upon copper binding to yCCS. Yet given the copy number of intracellular yCCS (3) and estimates of the dimerization constants, we suspect that the amount of yCCS homodimer in the cell is relatively low. 1quv NO 1 1 NPS NPS 10574802 10574802 HCV RdRp exists primarily as a monomer -- Annotation transfered from 1gx6 1qv0 PROBNOT 1 1 NPS NPS 14592432 14592432 Paper does not mention a dimer - PISA says monomer -- Annotation transfered from 1jf2 1qv1 PROBNOT 1 1 NPS NPS 14592432 14592432 Paper does not mention a dimer - PISA says monomer -- Annotation transfered from 1jf2 1qv6 NO 2 2 C2 C2 15023053 15023053 -- Annotation transfered from 8adh 1qv7 NO 2 2 C2 C2 15023053 15023053 -- Annotation transfered from 8adh 1qva NO 1 1 NPS NPS 10606264 10606264 Paper says: Superdex-75 column (Pharmacia)+ eIF4A eluted at the volume expected for a monomeric protein+ 1qvb NO 4 4 D2 D2 10094493 10094493 Paper says: This tetrameric arrangement is very similar to the one observed for the Gly-Sulfolobus structure 1qvc NO 4 4 D2 D2 10731701 10731701 Structure shown in paper 1qve PROBNOT 2 2 NS NS 15350129 15350129 Because it adopts a helical symmetry, this assembly could be right. 1qvr ART 3 6 NS C6 14567920 14567920 Normally forms a hexamer but I it seems not to appear in this structure 1qvs PROBNOT 1 1 NPS NPS 14556621 14556621 -- Annotation transfered from 1d9v 1qvv_1 PROBYES 2 2 NS C2 15130476 15130476 BU changed since last release and is now incorrect - found to be dimeric in solution (said in the paper) - interface completely different from the ones in the D3 protein 1g2i. - also different from 1ons. - automaticaly inferred from 1qvz 1qvv_2 PROBYES 2 2 NS C2 15130476 15130476 BU changed since last release and is now incorrect - found to be dimeric in solution (said in the paper) - interface completely different from the ones in the D3 protein 1g2i. - also different from 1ons. - automaticaly inferred from 1qvz 1qvw NO 2 2 C2 C2 15130476 15130476 found to be dimeric in solution (said in the paper) - interface completely different from the ones in the D3 protein 1g2i. - also different from 1ons. -- Annotation transfered from 1qvz 1qvz NO 2 2 C2 C2 15130476 15130476 found to be dimeric in solution (said in the paper) - interface completely different from the ones in the D3 protein 1g2i. - also different from 1ons. 1qw0 PROBNOT 1 1 NPS NPS 14556621 14556621 -- Annotation transfered from 1d9v 1qw4_1 PROBYES 2 1 C2 NPS 12954642 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1qw4_2 PROBYES 2 1 C2 NPS 12954642 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1qw5_1 PROBYES 2 1 C2 NPS 12954642 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1qw5_2 PROBYES 2 1 C2 NPS 12954642 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1qw6 NO 2 2 C2 C2 12954642 12954642 Clear dimer -- Annotation transfered from 1m00 1qwc NO 2 2 C2 C2 12954642 12954642 Clear dimer -- Annotation transfered from 1m00 1qwd YES 2 1 NS NPS 15044022 15044022 Paper mentions a gel-filtration exp and no dimer mentioned 1qwg NO 3 3 C3 C3 12952952 12952952 Interface geometry conserved with 1u83 (42%) 1qwh NO 4 4 D2 D2 15769474 0 transthyretin is tetrameric -- Annotation transfered from 1fh2 1qwl NO 4 4 D2 D2 15023060 15023060 Interface geometry conserved with 1mqf (60% id) -- interesting for folding (renaturation experiment) -- Annotation transfered from 1qwm 1qwm NO 4 4 D2 D2 15023060 15023060 Interface geometry conserved with 1mqf (60% id) -- interesting for folding (renaturation experiment) 1qx4 PROBYES 2 1 C2 NPS 14609324 14609324 Seems to be a monomeric protein 1qx5_1 PROBYES 2 1 C2 NPS 15130477 3145979 BU changed since last release and is now incorrect - - automaticaly inferred from 3cln 1qx5_2 PROBYES 2 1 C2 NPS 15130477 3145979 BU changed since last release and is now incorrect - - automaticaly inferred from 3cln 1qx5_3 PROBYES 2 1 C2 NPS 15130477 3145979 BU changed since last release and is now incorrect - - automaticaly inferred from 3cln 1qx5_4 PROBYES 2 1 C2 NPS 15130477 3145979 BU changed since last release and is now incorrect - - automaticaly inferred from 3cln 1qx8 PROBYES 4 2 D2 C2 16953576 15213408 Paper says: Rop is a homodimeric RNA-binding protein (Polisky, 1988) 1qxh NO 2 2 C2 C2 14506251 14506251 Interface geometry conserved with 1psq (46%) 1qxk PROBNOT 1 1 NPS NPS 14592481 14592481 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1qxs NO 4 4 D2 D2 14622286 0 SP says tetramer - papers too -- Annotation transfered from 1k3t 1qxt NO 1 1 NPS NPS 14523232 14523232 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1qy0 PROBNOT 1 1 NPS NPS 14871097 14871097 Gel filtration performed and no dimer or oligomer mentioned. -- Annotation transfered from 1i06 1qy1 PROBNOT 1 1 NPS NPS 14871097 14871097 Gel filtration performed and no dimer or oligomer mentioned. -- Annotation transfered from 1i06 1qy2 PROBNOT 1 1 NPS NPS 14871097 14871097 Gel filtration performed and no dimer or oligomer mentioned. -- Annotation transfered from 1i06 1qy3 NO 1 1 NPS NPS 14523232 14523232 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1qy5 NA 1 1 NPS NPS 12970348 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? 1qy7 NO 3 3 C3 C3 14646076 14646076 Interface geometry conserved with 1pil (66%) 1qy8 NA 1 1 NPS NPS 12970348 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? -- Annotation transfered from 1qy5 1qy9_1 PROBNOT 2 2 C2 C2 15103639 15545603 BU changed since last release and is now corrected - Paper says dimer - automaticaly inferred from 1sdj 1qy9_2 PROBNOT 2 2 C2 C2 15103639 15545603 BU changed since last release and is now corrected - Paper says dimer - automaticaly inferred from 1sdj 1qya NO 2 2 C2 C2 15103639 15103639 Exactly same interface as 1u0k (30% id) - must be functionaly relevant -- very interessting to illustrate how the conservation can be used to confirm a state (the protein eluted at 105kD which was inconclusive), also BioCyc annotation (Monomer) could be corrected for example. 1qyb NO 2 2 C2 C2 15023070 15023070 -- Annotation transfered from 1lkm 1qyc NO 2 2 C2 C2 13129921 13129921 Paper says dimer 1qye NA 1 1 NPS NPS 12970348 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? -- Annotation transfered from 1qy5 1qyf NO 1 1 NPS NPS 14523232 14523232 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1qyo NO 1 1 NPS NPS 14523232 14523232 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1qyq NO 1 1 NPS NPS 14523232 14523232 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1qyv NO 2 2 C2 C2 14966133 14966133 Paper says dimer -- Annotation transfered from 3dhe 1qyw NO 2 2 C2 C2 14966133 14966133 Paper says dimer -- Annotation transfered from 3dhe 1qyx NO 2 2 C2 C2 14966133 14966133 Paper says dimer -- Annotation transfered from 3dhe 1qyz NO 1 1 NPS NPS 15379555 0 -- Annotation transfered from 1dt1 1qz0_1 PROBNOT 1 1 NPS NPS 14609321 8052312 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1ypt 1qz0_2 PROBNOT 1 1 NPS NPS 14609321 8052312 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1ypt 1qz2 PROBYES 3 1 NS NPS 15159550 15159550 Paper implies monomeric 1qz3 PROBNOT 1 1 NPS NPS 14617621 14617621 Paper says: the protein, a monomeric B-type carboxylesterase of about 34 kDa, was purified and characterized. 1qz5 NO 1 1 NPS NPS 14578936 14578936 Actin exists in different states -- Annotation transfered from 1j6z 1qz6 NO 1 1 NPS NPS 14578936 14578936 Actin exists in different states -- Annotation transfered from 1j6z 1qz9 NO 2 2 C2 C2 14756555 14756555 1qzq PROBYES 2 1 C2 NPS 15111055 15111055 Paper does not mention a dimer, PISa says monomer and the first paper (1jy1) said monomer 1qzy PROBNOT 1 1 NPS NPS 14534293 14534293 Paper says nothing, PISA says monomer -- Annotation transfered from 1b6a 1qzz YES 1 2 NPS C2 14607118 14607118 Interface geometry conserved with 1tw2 (50% id) -- Annotation transfered from 1r00 1r00 YES 1 2 NPS C2 14607118 14607118 Interface geometry conserved with 1tw2 (50% id) 1r03 NO 24 24 Octa Octa 15201052 15201052 Interface geometry conserved with 1lb3 (49%) 1r0b NO 12 12 D3 D3 15157075 15157075 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1r0c NO 12 12 D3 D3 15157076 15157076 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1r0e PROBNOT 2 2 C2 C2 0 11440715 BU changed since last release and is now corrected - Paper says dimer detected in solution but the functional significance is unclear (autoinhibition is a possibility) - monomer/dimer equilibrium - automaticaly inferred from 1o9u 1r0f PROBNOT 1 1 NPS NPS 14747706 14747706 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1fhm 1r0g PROBNOT 1 1 NPS NPS 14747706 14747706 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1fhm 1r0h PROBNOT 1 1 NPS NPS 14747706 14747706 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1fhm 1r0i PROBNOT 1 1 NPS NPS 14747706 14747706 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1fhm 1r0j PROBNOT 1 1 NPS NPS 14747706 14747706 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1fhm 1r0p PROBNOT 1 1 NPS NPS 14559966 14559966 SP says: Heterodimer formed of an alpha chain (50 kDa) and a beta chain (145 kDa) which are disulfide linked. 1r0q NO 1 1 NPS NPS 15379555 0 -- Annotation transfered from 1dt1 1r18 PROBNOT 1 1 NPS NPS 14596598 14596598 SP says monomer 1r1d NO 2 2 C2 C2 0 15327954 Paper says enzyme active as a dimer (PISA wrong) 1r1l PROBNOT 2 2 C2 C2 0 15342247 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization - automatic transfer from 1jvq 1r1o NO 3 3 C3 C3 14570477 14570477 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference -- Annotation transfered from 1hqx 1r1w PROBNOT 1 1 NPS NPS 14559966 14559966 SP says: Heterodimer formed of an alpha chain (50 kDa) and a beta chain (145 kDa) which are disulfide linked. -- Annotation transfered from 1r0p 1r26 PROBNOT 1 1 NPS NPS 14623083 14623083 Paper says: Prolonged storage of recombinant T. brucei Trx can lead to the formation of covalent dimers. Sodium dodecyl sulfate–polyacrylamide gel electrophoresis of the stored protein sample without thiols in the sample buffer shows an additional band with a molecular mass of about 28 000, whereas under reducing conditions a single protein band of 13 000 is obtained - this is an oxidized form 1r2k YES 2 6 C2 D3 15159566 15159566 Paper says hexamer -- Annotation transfered from 1mkz 1r2q NO 1 1 NPS NPS 14684892 0 1r2r_1 NO 2 2 C2 C2 14643664 0 Interface geometry conserved with 1m6j (50%) - automatic transfer from 1r2t 1r2r_2 NO 2 2 C2 C2 14643664 0 Interface geometry conserved with 1m6j (50%) - automatic transfer from 1r2t 1r2s_1 NO 2 2 C2 C2 14643664 0 Interface geometry conserved with 1m6j (50%) - automatic transfer from 1r2t 1r2s_2 NO 2 2 C2 C2 14643664 0 Interface geometry conserved with 1m6j (50%) - automatic transfer from 1r2t 1r2t NO 2 2 C2 C2 14643664 0 Interface geometry conserved with 1m6j (50%) 1r2y PROBNOT 1 1 NPS NPS 14525999 9224623 Paper says: DNA glycosylases are relatively small monomeric proteins that do not require cofactors for their activity, 1r2z PROBNOT 1 1 NPS NPS 14525999 14525999 Paper says: DNA glycosylases are relatively small monomeric proteins that do not require cofactors for their activity, -- Annotation transfered from 1r2y 1r31 PROBNOT 2 2 C2 C2 0 0 Paper says dimer although no hard evidence is given. -- Annotation transfered from 1qax 1r35 PROBYES 2 1 C2 NPS 14599013 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1r37 NO 4 4 D2 D2 14661950 14661950 SP says homodimer and homotetramer - equilibium? 1r38_1 NO 2 2 C2 C2 15109252 12102621 Forms a dimer, paper interesting regarding the evolution of oligomeric state - good candidate - automatic transfer from 1jez 1r38_2 NO 2 2 C2 C2 15109252 12102621 Forms a dimer, paper interesting regarding the evolution of oligomeric state - good candidate - automatic transfer from 1jez 1r39 PROBNOT 1 1 NPS NPS 14726206 0 -- Annotation transfered from 1kv1 1r3c PROBNOT 1 1 NPS NPS 14726206 0 -- Annotation transfered from 1kv1 1r3q YES 2 2 NS C2 14633982 14633982 Interface geometry conserved with 1j93 (35%) 1r3r YES 2 2 NS C2 14633982 14633982 Interface geometry conserved with 1j93 (35%) -- Annotation transfered from 1r3q 1r3s YES 2 2 NS C2 14633982 14633982 Interface geometry conserved with 1j93 (35%) -- Annotation transfered from 1r3q 1r3t YES 2 2 NS C2 14633982 14633982 Interface geometry conserved with 1j93 (35%) -- Annotation transfered from 1r3q 1r3v YES 2 2 NS C2 14633982 14633982 Interface geometry conserved with 1j93 (35%) -- Annotation transfered from 1r3q 1r3w YES 2 2 NS C2 14633982 14633982 Interface geometry conserved with 1j93 (35%) -- Annotation transfered from 1r3q 1r3y YES 2 2 NS C2 14633982 14633982 Interface geometry conserved with 1j93 (35%) -- Annotation transfered from 1r3q 1r46 NO 2 2 C2 C2 15003450 15003450 Interface geometry conserved with 1ktc (53%) -- Annotation transfered from 1r47 1r47 NO 2 2 C2 C2 15003450 15003450 Interface geometry conserved with 1ktc (53%) 1r4f NO 2 2 C2 C2 15050818 15050818 Paper says dimer: The T. vivax IAG-NH is a homodimer, with each subunit consisting of ten beta-strands, 12 alpha-helices and three small 3(10)-helices. - We estimated the apparent molecular mass of the active nucleoside hydrolase from T. vivax using gel chromatography on a 10/30 Superdex-200 HR column. The enzyme elutes with a distribution coefficient (Kd in equation (1)) of 0.42 corresponding to a calculated molecular mass of 59,600 Da. Denaturing polyacrylamide gel electrophoresis gave a single band with a subunit molecular mass of approximately 35,000 Da, consistent with the predicted subunit molecular mass of 37,584 Da. -- Annotation transfered from 1hoz 1r4i NO 2 2 C2 C2 15037741 15037741 Interface geometry conserved with 1r4r (73% id). 1r4o NO 2 2 C2 C2 1865905 1865905 Interface geometry conserved with 1r4i (73% id). -- Annotation transfered from 1r4r 1r4r NO 2 2 C2 C2 1865905 1865905 Interface geometry conserved with 1r4i (73% id). 1r4z_1 PROBNOT 1 1 NPS NPS 16342303 12077437 PISA says monomer and related proteins are monomeric - automatic transfer from 1isp 1r4z_2 PROBNOT 1 1 NPS NPS 16342303 12077437 PISA says monomer and related proteins are monomeric - automatic transfer from 1isp 1r50_1 PROBNOT 1 1 NPS NPS 16342303 12077437 PISA says monomer and related proteins are monomeric - automatic transfer from 1isp 1r50_2 PROBNOT 1 1 NPS NPS 16342303 12077437 PISA says monomer and related proteins are monomeric - automatic transfer from 1isp 1r58 PROBNOT 1 1 NPS NPS 15012983 9812898 Paper says nothing, PISA says monomer - automatic transfer from 1b6a 1r5a NO 2 2 C2 C2 15717864 15717864 1r5b PROBNOT 1 1 NPS NPS 15099522 15099522 Paper does not mention oligomer, related structures are monomers and PISa says monomer -- Annotation transfered from 1r5o 1r5c NO 2 2 C2 C2 15048772 15048772 -- Annotation transfered from 11ba 1r5d NO 2 2 C2 C2 15048772 15048772 -- Annotation transfered from 11ba 1r5g PROBNOT 1 1 NPS NPS 15012983 9812898 Paper says nothing, PISA says monomer - automatic transfer from 1b6a 1r5h PROBNOT 1 1 NPS NPS 15012983 9812898 Paper says nothing, PISA says monomer - automatic transfer from 1b6a 1r5k_1 NO 2 2 C2 C2 15893725 9338790 paper says dimer - automatic transfer from 1err 1r5k_2 NO 2 2 C2 C2 15893725 9338790 paper says dimer - automatic transfer from 1err 1r5n PROBNOT 1 1 NPS NPS 15099522 15099522 Paper does not mention oligomer, related structures are monomers and PISa says monomer -- Annotation transfered from 1r5o 1r5o PROBNOT 1 1 NPS NPS 15099522 15099522 Paper does not mention oligomer, related structures are monomers and PISa says monomer 1r5q YES 1 2 NPS C2 15071498 15071498 Interface geometry conserved with 1v2z (50% id) 1r64_1 NA 1 1 NPS NPS 14992578 17426142 Papers do not give information and PISA suggests a dimer. -- Annotation transfered from 2id4_2 1r64_2 NA 1 1 NPS NPS 14992578 17426142 Papers do not give information and PISA suggests a dimer. -- Annotation transfered from 2id4_2 1r66 YES 2 2 NS C2 14570895 14570895 BU changed since last release and is now incorrect - Paper says dimer 1r67 PROBNOT 1 1 NPS NPS 0 0 1r69 PROBYES 1 2 NPS C2 2926803 2926803 1r6d YES 2 2 NS NS 14570895 14570895 paper says symmetric dimer 1r6j PROBNOT 1 1 NPS NPS 15081807 15081807 SwissProt says is exists as monomer / dimer -- Annotation transfered from 1nte 1r6k NO 1 1 NPS NPS 14634007 14634007 Paper says: Collectively, these results indicate that the HPV11 E2 TAD is fully monomeric in solution over the concentration range studied, up to ~20 µM 1r6l NO 6 6 D3 D3 14573594 14573594 Paper says hexamer -- Annotation transfered from 1r6m 1r6m NO 6 6 D3 D3 14573594 14573594 Paper says hexamer 1r6n NO 1 1 NPS NPS 14634007 14634007 Paper says: Collectively, these results indicate that the HPV11 E2 TAD is fully monomeric in solution over the concentration range studied, up to ~20 µM -- Annotation transfered from 1r6k 1r6w PROBYES 2 1 C2 NPS 14661953 15134446 Paper says monomer 1r6x NO 1 1 NPS NPS 14983089 14983089 Paper says: Here we show that truncation of this domain results in a monomeric enzyme with slightly enhanced catalytic efficiency. -- very interesting case: oligomerization impaired but catalytic efficiency increased!!! Also interesting for a future analysis where I could look at QS transitions based on domain recruitment. Also could be interesting to ask them directly if this truncated enzyme is OK in E. coli. 1r74 NO 4 4 D2 D2 15340920 15340920 Expressed human, rat and mouse GNMTs were tetramers as they were eluted from the Superose-12 column in one peak with elution volumes of 12.55, 12.73 and 12.90 mL for human, mouse and rat proteins respectively. This corresponds to an apparent Mr of 130 kDa (data not shown). While the differences in elution volume of GNMTs were small, they were reproducible in different buffers. 1r78 NO 1 1 NPS NPS 15012993 15012993 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1r7a NO 2 2 C2 C2 14756551 14756551 Paper says: Native molecular weight determination indicated that BiSP is a homodimer in solution, estimated by gel filtration experiments at pH 6.5. To verify the dimer formation at crystallization pH, dynamic light scattering was performed. Results confirmed dimer formation at crystallization pH 8.5 and at pH 6.5 (data not shown) 1r7h NO 2 2 C2 C2 15103625 15103625 Domain Swapped 1r7i PROBNOT 2 2 C2 C2 0 0 Paper says dimer although no hard evidence is given. -- Annotation transfered from 1qax 1r7o PROBNOT 1 1 NPS NPS 0 0 Paper does not mention oligom. state - PISA says monomer -- Annotation transfered from 1j9y 1r7t PROBYES 1 2 NPS C2 12972418 12972418 15475562 says: The dimerization observed for the soluble construct of O2 mutant enzyme is also observed in the wild-type GTA and GTB structures. An examination of glycosyltransferases with related folds with known structure shows that this dimerization through the N-terminal residues is not a general feature but is specific to the crystal packing of GTA, GTB, and their mutants. - PISA says dimer too -- Annotation transfered from 1lzj 1r7u PROBYES 1 2 NPS C2 12972418 12972418 15475562 says: The dimerization observed for the soluble construct of O2 mutant enzyme is also observed in the wild-type GTA and GTB structures. An examination of glycosyltransferases with related folds with known structure shows that this dimerization through the N-terminal residues is not a general feature but is specific to the crystal packing of GTA, GTB, and their mutants. - PISA says dimer too -- Annotation transfered from 1lzj 1r7v PROBYES 1 2 NPS C2 12972418 12972418 15475562 says: The dimerization observed for the soluble construct of O2 mutant enzyme is also observed in the wild-type GTA and GTB structures. An examination of glycosyltransferases with related folds with known structure shows that this dimerization through the N-terminal residues is not a general feature but is specific to the crystal packing of GTA, GTB, and their mutants. - PISA says dimer too -- Annotation transfered from 1lzj 1r7x PROBYES 1 2 NPS C2 12972418 12972418 15475562 says: The dimerization observed for the soluble construct of O2 mutant enzyme is also observed in the wild-type GTA and GTB structures. An examination of glycosyltransferases with related folds with known structure shows that this dimerization through the N-terminal residues is not a general feature but is specific to the crystal packing of GTA, GTB, and their mutants. - PISA says dimer too -- Annotation transfered from 1lzj 1r7y PROBYES 1 2 NPS C2 12972418 12972418 15475562 says: The dimerization observed for the soluble construct of O2 mutant enzyme is also observed in the wild-type GTA and GTB structures. An examination of glycosyltransferases with related folds with known structure shows that this dimerization through the N-terminal residues is not a general feature but is specific to the crystal packing of GTA, GTB, and their mutants. - PISA says dimer too -- Annotation transfered from 1lzj 1r80 PROBYES 1 2 NPS C2 12972418 12972418 15475562 says: The dimerization observed for the soluble construct of O2 mutant enzyme is also observed in the wild-type GTA and GTB structures. An examination of glycosyltransferases with related folds with known structure shows that this dimerization through the N-terminal residues is not a general feature but is specific to the crystal packing of GTA, GTB, and their mutants. - PISA says dimer too -- Annotation transfered from 1lzj 1r81 PROBYES 1 2 NPS C2 12972418 12972418 15475562 says: The dimerization observed for the soluble construct of O2 mutant enzyme is also observed in the wild-type GTA and GTB structures. An examination of glycosyltransferases with related folds with known structure shows that this dimerization through the N-terminal residues is not a general feature but is specific to the crystal packing of GTA, GTB, and their mutants. - PISA says dimer too -- Annotation transfered from 1lzj 1r82 PROBYES 1 2 NPS C2 12972418 12972418 15475562 says: The dimerization observed for the soluble construct of O2 mutant enzyme is also observed in the wild-type GTA and GTB structures. An examination of glycosyltransferases with related folds with known structure shows that this dimerization through the N-terminal residues is not a general feature but is specific to the crystal packing of GTA, GTB, and their mutants. - PISA says dimer too -- Annotation transfered from 1lzj 1r89 NO 2 2 C2 C2 14636575 14636575 1r8a NO 2 2 C2 C2 14636575 14636575 -- Annotation transfered from 1r89 1r8b NO 2 2 C2 C2 14636575 14636575 -- Annotation transfered from 1r89 1r8c NO 2 2 C2 C2 14636575 14636575 -- Annotation transfered from 1r89 1r8w NO 2 2 C2 C2 15096031 0 Same interface geometry as 1h18 despite sequence similarity < 30% 1r8x NO 4 4 D2 D2 15340920 15340920 Expressed human, rat and mouse GNMTs were tetramers as they were eluted from the Superose-12 column in one peak with elution volumes of 12.55, 12.73 and 12.90 mL for human, mouse and rat proteins respectively. This corresponds to an apparent Mr of 130 kDa (data not shown). While the differences in elution volume of GNMTs were small, they were reproducible in different buffers. 1r8y_1 NO 4 4 D2 D2 15340920 15340920 Expressed human, rat and mouse GNMTs were tetramers as they were eluted from the Superose-12 column in one peak with elution volumes of 12.55, 12.73 and 12.90 mL for human, mouse and rat proteins respectively. This corresponds to an apparent Mr of 130 kDa (data not shown). While the differences in elution volume of GNMTs were small, they were reproducible in different buffers. - automatic transfer from 1r8x 1r8y_2 NO 4 4 D2 D2 15340920 15340920 Expressed human, rat and mouse GNMTs were tetramers as they were eluted from the Superose-12 column in one peak with elution volumes of 12.55, 12.73 and 12.90 mL for human, mouse and rat proteins respectively. This corresponds to an apparent Mr of 130 kDa (data not shown). While the differences in elution volume of GNMTs were small, they were reproducible in different buffers. - automatic transfer from 1r8x 1r9d NO 2 2 C2 C2 15096031 0 Same interface geometry as 1h18 despite sequence similarity < 30% -- Annotation transfered from 1r8w 1r9e NO 2 2 C2 C2 15096031 0 Same interface geometry as 1h18 despite sequence similarity < 30% -- Annotation transfered from 1r8w 1r9h PROBNOT 1 1 NPS NPS 0 0 No paper - I rely on PISA prediction 1r9m_1 NO 2 2 C2 C2 14718659 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 1r9m_2 NO 2 2 C2 C2 14718659 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 1r9n_1 NO 2 2 C2 C2 14718659 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 1r9n_2 PROBYES 2 2 NS C2 14718659 15175333 BU changed since last release and is now incorrect - Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automaticaly inferred from 1tkr 1r9o PROBNOT 1 1 NPS NPS 15181000 15181000 Paper does not speak about dimer - PISA says monomer and found this http://pubs.acs.org/subscribe/journals/jacsat/suppinfo/ja0608693/ja0608693.pdf where they describe a monomer too 1r9w NO 1 1 NPS NPS 14593106 14593106 Paper says: While monomeric in solution, E1 binds DNA as a dimer. Dimerization occurs via an interaction of hydrophobic residues on a single {alpha}-helix of each monomer. Here we present the crystal structure of the monomeric HPV-18 E1 DNA-binding domain refined to 1.8-Å resolution. - DNA induced dimerization -- interesting 1r9x PROBNOT 6 6 D3 D3 15381761 11812140 Paper says: The bacterial enzyme is a hexamer of approximately 426 amino acid residues per subunit, giving a mass of approximately 300 kDa for the active enzyme complex. The yeast enzyme is a homodimer consisting of 17 kDa per subunit. - automatic transfer from 1k70 1r9y PROBNOT 6 6 D3 D3 15381761 11812140 Paper says: The bacterial enzyme is a hexamer of approximately 426 amino acid residues per subunit, giving a mass of approximately 300 kDa for the active enzyme complex. The yeast enzyme is a homodimer consisting of 17 kDa per subunit. - automatic transfer from 1k70 1r9z PROBNOT 6 6 D3 D3 15381761 11812140 Paper says: The bacterial enzyme is a hexamer of approximately 426 amino acid residues per subunit, giving a mass of approximately 300 kDa for the active enzyme complex. The yeast enzyme is a homodimer consisting of 17 kDa per subunit. - automatic transfer from 1k70 1ra0 PROBNOT 6 6 D3 D3 15381761 11812140 Paper says: The bacterial enzyme is a hexamer of approximately 426 amino acid residues per subunit, giving a mass of approximately 300 kDa for the active enzyme complex. The yeast enzyme is a homodimer consisting of 17 kDa per subunit. - automatic transfer from 1k70 1ra1 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1ra2 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1ra3 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1ra5 PROBNOT 6 6 D3 D3 15381761 11812140 Paper says: The bacterial enzyme is a hexamer of approximately 426 amino acid residues per subunit, giving a mass of approximately 300 kDa for the active enzyme complex. The yeast enzyme is a homodimer consisting of 17 kDa per subunit. - automatic transfer from 1k70 1ra8 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1ra9 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1raa NO 12 12 D3 D3 8441751 8441751 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) 1rab NO 12 12 D3 D3 8441751 8441751 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1rac NO 12 12 D3 D3 8441751 8441751 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1rad NO 12 12 D3 D3 8441751 8441751 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1rae NO 12 12 D3 D3 8441751 8441751 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1raf NO 12 12 D3 D3 8441751 8441751 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1rag NO 12 12 D3 D3 8441751 8441751 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1rah NO 12 12 D3 D3 8441751 8441751 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1rai NO 12 12 D3 D3 8441751 8441751 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1rak PROBNOT 6 6 D3 D3 15381761 11812140 Paper says: The bacterial enzyme is a hexamer of approximately 426 amino acid residues per subunit, giving a mass of approximately 300 kDa for the active enzyme complex. The yeast enzyme is a homodimer consisting of 17 kDa per subunit. - automatic transfer from 1k70 1ral PROBNOT 1 1 NPS NPS 8146147 8146147 1rao PROBNOT 1 1 NPS NPS 15016362 11546767 EcoCyc & SP say monomer. - automatic transfer from 1eqm 1rap PROBYES 2 1 C2 NPS 8401228 8401228 1raq PROBYES 2 1 C2 NPS 8401228 8401228 -- Annotation transfered from 1rap 1rar NO 1 1 NPS NPS 8357795 8357795 -- Annotation transfered from 6rsa 1ras NO 1 1 NPS NPS 8357795 8357795 -- Annotation transfered from 6rsa 1rat NO 1 1 NPS NPS 1547232 1547232 -- Annotation transfered from 6rsa 1rav NO 4 4 D2 D2 9760187 9760187 Avidin is a clear tetramer -- Annotation transfered from 2cam 1ray PROBNOT 1 1 NPS NPS 8482389 8482389 9000633 says monomeric -- Annotation transfered from 1uga 1raz PROBNOT 1 1 NPS NPS 8482389 8482389 9000633 says monomeric -- Annotation transfered from 1uga 1rb0 PROBNOT 1 1 NPS NPS 15016362 11546767 EcoCyc & SP say monomer. - automatic transfer from 1eqm 1rb1 NO 3 3 NS NS 14752198 14752198 Paper says trimer -- false positive with symmetry search? -- Annotation transfered from 1rb6 1rb2 PROBYES 2 1 C2 NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1dds 1rb3 PROBYES 2 1 C2 NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1dds 1rb4 NO 3 3 NS NS 14752198 14752198 Paper says trimer -- false positive with symmetry search? -- Annotation transfered from 1rb6 1rb5 NO 3 3 NS NS 14752198 14752198 Paper says trimer -- false positive with symmetry search? -- Annotation transfered from 1rb6 1rb6 NO 3 3 NS NS 14752198 14752198 Paper says trimer -- false positive with symmetry search? 1rb9 PROBNOT 1 1 NPS NPS 0 0 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 7rxn 1rba NO 2 2 C2 C2 1606957 1606957 Paper says: In contrast to the hexadecameric plant enzyme, ribulose-P2 carboxylase from Rhodospirillum rubrum is a dimer of only large subunits. -- Annotation transfered from 1rus 1rbb YES 2 1 NS NPS 3680242 3680242 No domain swapping - Known as a monomer, SP and PISA say monomer 1rbc NO 1 1 NPS NPS 1463720 1463720 -- Annotation transfered from 6rsa 1rbd NO 1 1 NPS NPS 1463720 1463720 -- Annotation transfered from 6rsa 1rbe NO 1 1 NPS NPS 1463720 1463720 -- Annotation transfered from 6rsa 1rbf NO 1 1 NPS NPS 1463720 1463720 -- Annotation transfered from 6rsa 1rbg NO 1 1 NPS NPS 1463720 1463720 -- Annotation transfered from 6rsa 1rbh NO 1 1 NPS NPS 1463720 1463720 -- Annotation transfered from 6rsa 1rbi NO 1 1 NPS NPS 1463720 1463720 -- Annotation transfered from 6rsa 1rbj PROBNOT 1 1 NPS NPS 15299737 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1rbl NA 16 16 D4 D4 15299492 15299492 BU changed since last release and is now corrected - -- PISA cannot reconstruct it, I see only 8 chains, I dont understand 1rbm_1 NO 1 1 NPS NPS 0 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1rbm_2 NO 1 1 NPS NPS 0 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1rbn NO 1 1 NPS NPS 8051049 8051049 -- Annotation transfered from 6rsa 1rbp NO 1 1 NPS NPS 2217163 2217163 Serum retinol binding protein (RBP) is a monomeric protein of molecular weight 21,000 that transports vitamin A in the circulation -- Annotation transfered from 1jyd 1rbq_1 NO 1 1 NPS NPS 0 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1rbq_2 NO 1 1 NPS NPS 0 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1rbq_3 NO 1 1 NPS NPS 0 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1rbq_4 NO 1 1 NPS NPS 0 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1rbr PROBNOT 1 1 NPS NPS 8381958 8381958 SP says monomer -- Annotation transfered from 1f21 1rbs PROBNOT 1 1 NPS NPS 8381958 8381958 SP says monomer -- Annotation transfered from 1f21 1rbt PROBNOT 1 1 NPS NPS 8381958 8381958 SP says monomer -- Annotation transfered from 1f21 1rbu PROBNOT 1 1 NPS NPS 8381958 8381958 SP says monomer -- Annotation transfered from 1f21 1rbv PROBNOT 1 1 NPS NPS 8381958 8381958 SP says monomer -- Annotation transfered from 1f21 1rbw NO 1 1 NPS NPS 9260285 9260285 -- Annotation transfered from 6rsa 1rbx NO 1 1 NPS NPS 9260285 9260285 -- Annotation transfered from 6rsa 1rby_1 NO 1 1 NPS NPS 0 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1rby_2 NO 1 1 NPS NPS 0 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1rby_3 NO 1 1 NPS NPS 0 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1rby_4 NO 1 1 NPS NPS 0 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1rbz_1 NO 1 1 NPS NPS 0 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1rbz_2 NO 1 1 NPS NPS 0 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1rc0_1 NO 1 1 NPS NPS 0 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1rc0_2 NO 1 1 NPS NPS 0 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1rc1_1 NO 1 1 NPS NPS 0 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1rc1_2 NO 1 1 NPS NPS 0 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1rc4 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1rca NO 1 1 NPS NPS 15299807 0 -- Annotation transfered from 6rsa 1rcb PROBYES 2 1 C2 NPS 1511746 1511746 In a cell paper, binds receptor as a monomer (10219247)- in a JBC paper, purified as a monomer (7706290) - PISA says monomer -- Annotation transfered from 1hij 1rcc NO 24 24 Octa Octa 7760335 7760335 Interface geometry conserved with 1lb3 (48%) -- Annotation transfered from 1rcd 1rcd NO 24 24 Octa Octa 7760335 7760335 Interface geometry conserved with 1lb3 (48%) 1rce NO 24 24 Octa Octa 7760335 7760335 Interface geometry conserved with 1lb3 (48%) -- Annotation transfered from 1rcd 1rcf PROBNOT 1 1 NPS NPS 15299298 0 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1ftg 1rcg NO 24 24 Octa Octa 7760335 7760335 Interface geometry conserved with 1lb3 (48%) -- Annotation transfered from 1rcd 1rci NO 24 24 Octa Octa 7760335 7760335 Interface geometry conserved with 1lb3 (48%) -- Annotation transfered from 1rcd 1rcj PROBNOT 1 1 NPS NPS 14744126 14744126 -- Annotation transfered from 1ong 1rcm YES 2 1 C2 NPS 8387211 8387211 1rcn NO 1 1 NPS NPS 8063789 8063789 -- Annotation transfered from 6rsa 1rcp_1 PROBNOT 1 1 NPS NPS 8676382 15299853 Most cytochromes c prime are dimeric with each molecule comprising a left-handed four-a-helix bundle with a heme group attached to a Cys-X-X-Cys-His site near the carboxyl terminus. However, Rhodobacter capsulatus and R. sphaeroides cytochromes c prime appear to exist as equilibrium mixtures of monomers and dimers, and only R. palustris cytochrome c prime is completely monomeric(Cusanovich, 1971). - automatic transfer from 1cpr 1rcp_2 PROBNOT 1 1 NPS NPS 8676382 15299853 Most cytochromes c prime are dimeric with each molecule comprising a left-handed four-a-helix bundle with a heme group attached to a Cys-X-X-Cys-His site near the carboxyl terminus. However, Rhodobacter capsulatus and R. sphaeroides cytochromes c prime appear to exist as equilibrium mixtures of monomers and dimers, and only R. palustris cytochrome c prime is completely monomeric(Cusanovich, 1971). - automatic transfer from 1cpr 1rct YES 1 3 NPS C3 14706628 14706628 Paper says trimer 1rcy PROBNOT 1 1 NPS NPS 8947572 8947572 SP says monomer 1rd4_1 PROBNOT 1 1 NPS NPS 14992576 7479767 BU changed since last release and is now corrected - Interface very small - probably monomer - automaticaly inferred from 1lfa 1rd4_2 PROBNOT 1 1 NPS NPS 14992576 7479767 BU changed since last release and is now corrected - Interface very small - probably monomer - automaticaly inferred from 1lfa 1rd4_3 PROBNOT 1 1 NPS NPS 14992576 7479767 BU changed since last release and is now corrected - Interface very small - probably monomer - automaticaly inferred from 1lfa 1rd4_4 PROBNOT 1 1 NPS NPS 14992576 7479767 BU changed since last release and is now corrected - Interface very small - probably monomer - automaticaly inferred from 1lfa 1rd6 PROBNOT 1 1 NPS NPS 0 9495026 BU changed since last release and is now corrected - The weight they find in that paper is compatible with a monomer - automaticaly inferred from 1ctn 1rd7 PROBYES 2 1 C2 NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1dds 1rda PROBNOT 1 1 NPS NPS 8408067 8408067 SP says monomer -- Annotation transfered from 1f21 1rdb PROBNOT 1 1 NPS NPS 8408067 8408067 SP says monomer -- Annotation transfered from 1f21 1rdc PROBNOT 1 1 NPS NPS 8408067 8408067 SP says monomer -- Annotation transfered from 1f21 1rdd PROBNOT 1 1 NPS NPS 8108376 8108376 SP says monomer -- Annotation transfered from 1f21 1rdg PROBNOT 1 1 NPS NPS 3441010 3441010 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes 1rdh_1 PROBNOT 1 1 NPS NPS 15299518 1707186 BU changed since last release and is now corrected - 123 aa of a >1400 aa protein. This contact is probably an artifact. - automaticaly inferred from 1hrh 1rdh_2 PROBNOT 1 1 NPS NPS 15299518 1707186 BU changed since last release and is now corrected - 123 aa of a >1400 aa protein. This contact is probably an artifact. - automaticaly inferred from 1hrh 1rdi PROBNOT 2 2 C2 C2 8557671 8557671 The fragment elutes with an apparent molecular weight of 21 kDa from a gel filtration column (data not shown). Since the polypeptide molecular weight is 13 kDa, the elution position suggests that the fragment is dimeric. This conclusion is supported by cross-linking data. -- interesting: I am not sure but read the paper more carefully: seems to undergo a shift in oligomeric state when cutting part of the structure?? 1rdj PROBNOT 2 2 C2 C2 8557671 8557671 The fragment elutes with an apparent molecular weight of 21 kDa from a gel filtration column (data not shown). Since the polypeptide molecular weight is 13 kDa, the elution position suggests that the fragment is dimeric. This conclusion is supported by cross-linking data. -- interesting: I am not sure but read the paper more carefully: seems to undergo a shift in oligomeric state when cutting part of the structure?? -- Annotation transfered from 1rdi 1rdk PROBNOT 2 2 C2 C2 8557671 8557671 The fragment elutes with an apparent molecular weight of 21 kDa from a gel filtration column (data not shown). Since the polypeptide molecular weight is 13 kDa, the elution position suggests that the fragment is dimeric. This conclusion is supported by cross-linking data. -- interesting: I am not sure but read the paper more carefully: seems to undergo a shift in oligomeric state when cutting part of the structure?? -- Annotation transfered from 1rdi 1rdl PROBNOT 2 2 C2 C2 8557671 8557671 The fragment elutes with an apparent molecular weight of 21 kDa from a gel filtration column (data not shown). Since the polypeptide molecular weight is 13 kDa, the elution position suggests that the fragment is dimeric. This conclusion is supported by cross-linking data. -- interesting: I am not sure but read the paper more carefully: seems to undergo a shift in oligomeric state when cutting part of the structure?? -- Annotation transfered from 1rdi 1rdm PROBNOT 2 2 C2 C2 8557671 8557671 The fragment elutes with an apparent molecular weight of 21 kDa from a gel filtration column (data not shown). Since the polypeptide molecular weight is 13 kDa, the elution position suggests that the fragment is dimeric. This conclusion is supported by cross-linking data. -- interesting: I am not sure but read the paper more carefully: seems to undergo a shift in oligomeric state when cutting part of the structure?? -- Annotation transfered from 1rdi 1rdn PROBNOT 2 2 C2 C2 8557671 8557671 The fragment elutes with an apparent molecular weight of 21 kDa from a gel filtration column (data not shown). Since the polypeptide molecular weight is 13 kDa, the elution position suggests that the fragment is dimeric. This conclusion is supported by cross-linking data. -- interesting: I am not sure but read the paper more carefully: seems to undergo a shift in oligomeric state when cutting part of the structure?? -- Annotation transfered from 1rdi 1rdo PROBNOT 2 2 C2 C2 8557671 8557671 The fragment elutes with an apparent molecular weight of 21 kDa from a gel filtration column (data not shown). Since the polypeptide molecular weight is 13 kDa, the elution position suggests that the fragment is dimeric. This conclusion is supported by cross-linking data. -- interesting: I am not sure but read the paper more carefully: seems to undergo a shift in oligomeric state when cutting part of the structure?? -- Annotation transfered from 1rdi 1rdq NO 1 1 NPS NPS 14757059 14757059 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1rdv PROBNOT 1 1 NPS NPS 10089348 10089348 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes 1rdw YES 2 1 C2 NPS 15099571 15099571 Actin does not form closed dimer -- Annotation transfered from 1lcu 1rdx NO 4 4 D2 D2 8844845 8844845 -- Annotation transfered from 1eyi 1rdy NO 4 4 D2 D2 8844845 8844845 -- Annotation transfered from 1eyi 1rdz NO 4 4 D2 D2 8844845 8844845 -- Annotation transfered from 1eyi 1re2 NO 1 1 NPS NPS 9888793 9888793 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1re5 NO 4 4 D2 D2 15301541 15301541 Interface geometry conserved with 1vdk (26%) 1re7 PROBYES 2 1 C2 NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1dds 1re8 NO 1 1 NPS NPS 14705934 14705934 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1re9 PROBNOT 1 1 NPS NPS 15522298 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1rea ART 1 6 NPS NS 1731253 1731253 1rec PROBYES 4 1 C4 NPS 8242744 1358206 The elution volume of recoverin corresponds to a monomer. 1rei NO 2 2 C2 C2 1182131 1182131 Paper says dimer -- Annotation transfered from 1ar2 1rej NO 1 1 NPS NPS 14705934 14705934 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1rek NO 1 1 NPS NPS 14705934 14705934 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1rem NO 1 1 NPS NPS 9757098 9757098 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1reo NA 2 1 C2 NPS 15103157 15103157 Interface is large but nothing about a dimer is mentioned in the paper 1rer PROBNOT 3 3 C3 C3 14737160 0 SP: p62 and E1 form a heterodimer shortly after synthesis. Processing of p62 into E2 and E3 results in a heterodimer of E2 and E1. Spike at virion surface are constituted of three E2-E1 heterodimers. After target cell attachment and endocytosis, E1 change conformation to form homotrimers. 1rex NO 1 1 NPS NPS 8885835 8885835 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1rey NO 1 1 NPS NPS 8885835 8885835 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1rez NO 1 1 NPS NPS 8885835 8885835 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1rf7 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1rf9 PROBNOT 1 1 NPS NPS 15522298 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1rfb NO 2 2 C2 C2 15299487 0 Native IFN-[gamma] exists as a homodimer. -- Annotation transfered from 1d9c 1rff_1 PROBNOT 1 1 NPS NPS 14761185 11839309 Paper says monomer - automatic transfer from 1jy1 1rff_2 PROBNOT 1 1 NPS NPS 14761185 11839309 Paper says monomer - automatic transfer from 1jy1 1rfg PROBNOT 3 3 C3 C3 15983407 14706628 BU changed since last release and is now corrected - Paper says trimer - automaticaly inferred from 1rct 1rfi_1 PROBNOT 1 1 NPS NPS 14761185 11839309 Paper says monomer - automatic transfer from 1jy1 1rfi_2 PROBNOT 1 1 NPS NPS 14761185 11839309 Paper says monomer - automatic transfer from 1jy1 1rfj PROBNOT 1 1 NPS NPS 15213382 15213382 Close homologs are monomers and PISA says monomer 1rfp NO 1 1 NPS NPS 9354379 9354379 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1rfq YES 2 1 C2 NPS 15099571 15099571 Actin does not form closed dimer -- Annotation transfered from 1lcu 1rft NO 2 2 C2 C2 14722069 14722069 Interface geometry conserved with 1ub0 (31%) -- Annotation transfered from 1lhr 1rfu_1 NO 2 2 C2 C2 14722069 12235162 Interface geometry conserved with 1ub0 (31%) - automatic transfer from 1lhr 1rfu_2 NO 2 2 C2 C2 14722069 12235162 Interface geometry conserved with 1ub0 (31%) - automatic transfer from 1lhr 1rfu_3 NO 2 2 C2 C2 14722069 12235162 Interface geometry conserved with 1ub0 (31%) - automatic transfer from 1lhr 1rfu_4 NO 2 2 C2 C2 14722069 12235162 Interface geometry conserved with 1ub0 (31%) - automatic transfer from 1lhr 1rfv NO 2 2 C2 C2 14722069 14722069 Interface geometry conserved with 1ub0 (31%) -- Annotation transfered from 1lhr 1rg0 PROBYES 2 2 C2 NS 15350129 15350129 Because it adopts a helical symmetry, this assembly is probably wrong 1rg1_1 PROBNOT 1 1 NPS NPS 14761185 11839309 Paper says monomer - automatic transfer from 1jy1 1rg1_2 PROBNOT 1 1 NPS NPS 14761185 11839309 Paper says monomer - automatic transfer from 1jy1 1rg2_1 PROBNOT 1 1 NPS NPS 14761185 11839309 Paper says monomer - automatic transfer from 1jy1 1rg2_2 PROBNOT 1 1 NPS NPS 14761185 11839309 Paper says monomer - automatic transfer from 1jy1 1rg7 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1rg8_1 PROBNOT 1 1 NPS NPS 15382229 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1rg8_2 PROBNOT 1 1 NPS NPS 15382229 8652550 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 2afg 1rg9 NO 4 4 D2 D2 14967023 14967023 1rge YES 2 1 NS NPS 15299705 0 11969396 says monomer -- Annotation transfered from 1gmp 1rgf YES 2 1 NS NPS 15299705 0 11969396 says monomer -- Annotation transfered from 1gmp 1rgg YES 2 1 NS NPS 15299705 0 11969396 says monomer -- Annotation transfered from 1gmp 1rgh YES 2 1 NS NPS 15299705 0 11969396 says monomer -- Annotation transfered from 1gmp 1rgt_1 PROBNOT 1 1 NPS NPS 14761185 11839309 Paper says monomer - automatic transfer from 1jy1 1rgt_2 PROBNOT 1 1 NPS NPS 14761185 11839309 Paper says monomer - automatic transfer from 1jy1 1rgu_1 PROBNOT 1 1 NPS NPS 14761185 11839309 Paper says monomer - automatic transfer from 1jy1 1rgu_2 PROBNOT 1 1 NPS NPS 14761185 11839309 Paper says monomer - automatic transfer from 1jy1 1rgz PROBNOT 1 1 NPS NPS 14660590 14660590 This is a class C beta Lactamase and those are monomeric (12951239) -- Annotation transfered from 1c3b -- Annotation transfered from 1ga0 1rh0_1 PROBNOT 1 1 NPS NPS 14761185 11839309 Paper says monomer - automatic transfer from 1jy1 1rh0_2 PROBNOT 1 1 NPS NPS 14761185 11839309 Paper says monomer - automatic transfer from 1jy1 1rh3 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1rha NO 1 1 NPS NPS 15299799 0 -- Annotation transfered from 6rsa 1rhb NO 1 1 NPS NPS 15299799 0 -- Annotation transfered from 6rsa 1rhg PROBYES 3 1 NS NPS 7685117 7685117 Paper implies monomer - SP says monomer 1rhp PROBNOT 4 4 D2 D2 8031770 8031770 SP says tetramer 1ri1 NO 1 1 NPS NPS 14731396 14731396 Paper says: cellular cap methyltransferases are monomeric enzymes -- Annotation transfered from 1ri4 1ri2 NO 1 1 NPS NPS 14731396 14731396 Paper says: cellular cap methyltransferases are monomeric enzymes -- Annotation transfered from 1ri4 1ri3 NO 1 1 NPS NPS 14731396 14731396 Paper says: cellular cap methyltransferases are monomeric enzymes -- Annotation transfered from 1ri4 1ri4 NO 1 1 NPS NPS 14731396 14731396 Paper says: cellular cap methyltransferases are monomeric enzymes 1ri5 NO 1 1 NPS NPS 14731396 14731396 Paper says: cellular cap methyltransferases are monomeric enzymes -- Annotation transfered from 1ri4 1ri7 NA 1 2 NPS C2 14976242 14976242 Paper says it forms disks, but these are not observed in the crystal: it adopts a helical symmetry. 1rir NO 4 4 C2 C2 15823017 8656429 Paper says tetramer - automatic transfer from 2pel 1ris NA 4 4 D2 D2 8137808 8137808 10944185 says that it forms dimers in small quantity (crosslinking exp). 1rit NO 4 4 C2 C2 15823017 8656429 Paper says tetramer - automatic transfer from 2pel 1riy NO 2 2 C2 C2 0 9757133 Domain Swapped dimer - automatic transfer from 1b8z 1rjb PROBNOT 1 1 NPS NPS 14759363 14759363 This tyrosine kinase recptor, like most of them dimerize upon ligand binding but the structure is in the inhibited form -- family remark: tyrosine K receptors are great examples for the importance of dimerization!!!! 1rjo NO 2 2 C2 C2 15533431 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 1rju PROBNOT 1 1 NPS NPS 15613489 15613489 Paper does not give information. PISA says monomer. 1rjw NO 4 4 D2 D2 15122892 15122892 1rjx PROBNOT 1 1 NPS NPS 15211511 15211511 Paper says nothing, similar prots are monomeric -- PISA says 24-mer!?? 1rk2_1 NO 2 2 C2 C2 10438599 9519409 Interface geometry conserved with 1vm7 (39%) - automatic transfer from 1rkd 1rk2_2 NO 2 2 C2 C2 10438599 9519409 Interface geometry conserved with 1vm7 (39%) - automatic transfer from 1rkd 1rk4 NO 2 2 C2 C2 14613939 14613939 1rka NO 2 2 C2 C2 10438599 10438599 Interface geometry conserved with 1vm7 (39%) -- Annotation transfered from 1rkd 1rkd NO 2 2 C2 C2 9519409 9519409 Interface geometry conserved with 1vm7 (39%) 1rkp PROBNOT 1 1 NPS NPS 14668322 14668322 No info about oligomer in all papers, PISa says monomer and inspection of the structure let think it is right. -- Annotation transfered from 1uho 1rks NO 2 2 C2 C2 10438599 10438599 Interface geometry conserved with 1vm7 (39%) -- Annotation transfered from 1rkd 1rkx NO 4 4 D2 D2 15023057 15023057 Paper says tetramer 1rl0 PROBNOT 1 1 NPS NPS 15681236 15553110 PISA says monomeric, plus most RIPs (ribo inact. prot.) are monomeric (type I) - automatic transfer from 1lpd 1rl9 NO 1 1 NPS NPS 14978299 14978299 Paper says: Arginine kinase is widespread in invertebrates and may be the primordial enzyme because of its widely available substrate, monomeric structure, and presence in protozoa -- interesting: very good family for QS evolution (close monomer, dimer and octamer) -- Annotation transfered from 1p52 1rla NO 3 3 C3 C3 8849731 8849731 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference -- Annotation transfered from 1hqx 1rle_1 PROBNOT 1 1 NPS NPS 14645372 11980702 BU changed since last release and is now corrected - Paper says: the protein is a monomer in solution - automaticaly inferred from 1l9m 1rle_2 PROBNOT 1 1 NPS NPS 14645372 11980702 BU changed since last release and is now corrected - Paper says: the protein is a monomer in solution - automaticaly inferred from 1l9m 1rli PROBNOT 4 4 D2 D2 0 0 PISA says it is a tetramer. I burries a lot of ASA so should be right. 1rlu PROBNOT 2 2 NS NS 15342249 0 Paper seem to give this dimer -- Annotation transfered from 1rq2 1rlw PROBNOT 1 1 NPS NPS 9430701 9430701 PISA says monomer 1rm0 NO 4 4 D2 D2 14684747 14684747 MIP synthase is a homotetramer both in solution and in the solid state -- Annotation transfered from 1jki 1rm9 NO 1 1 NPS NPS 15101562 15101562 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1rmh PROBYES 2 1 C2 NPS 8652511 8980234 BU changed since last release and is now incorrect - Paper implies CypA is monomeric - automaticaly inferred from 5cyh 1rmm NO 1 1 NPS NPS 15101562 15101562 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1rmo NO 1 1 NPS NPS 15101562 15101562 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1rmp NO 1 1 NPS NPS 15101562 15101562 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1rmr NO 2 2 C2 C2 15317139 15317139 Disulfide linked homodimer 1rnb NO 1 1 NPS NPS 2023257 2023257 1yvs is a domain swapped trimer but this one is a monomer (7473729) -- interesting: Jane Clark, Kim Henrick and Alan Fersht had a paper together! 1rnc NO 1 1 NPS NPS 1548704 1548704 -- Annotation transfered from 6rsa 1rnd NO 1 1 NPS NPS 1548704 1548704 -- Annotation transfered from 6rsa 1rne PROBYES 2 1 C2 NPS 1807356 1807356 1rnh PROBNOT 1 1 NPS NPS 2169648 2169648 SP says monomer -- Annotation transfered from 1f21 1rnm NO 1 1 NPS NPS 0 0 -- Annotation transfered from 6rsa 1rnn NO 1 1 NPS NPS 0 0 -- Annotation transfered from 6rsa 1rno NO 1 1 NPS NPS 8973167 8973167 -- Annotation transfered from 6rsa 1rnq NO 1 1 NPS NPS 8973167 8973167 -- Annotation transfered from 6rsa 1rnu NO 1 1 NPS NPS 1463719 1463719 -- Annotation transfered from 6rsa 1rnv NO 1 1 NPS NPS 1463719 1463719 -- Annotation transfered from 6rsa 1rnw NO 1 1 NPS NPS 8973167 8973167 -- Annotation transfered from 6rsa 1rnx NO 1 1 NPS NPS 8973167 8973167 -- Annotation transfered from 6rsa 1rny NO 1 1 NPS NPS 8973167 8973167 -- Annotation transfered from 6rsa 1rnz NO 1 1 NPS NPS 8973167 8973167 -- Annotation transfered from 6rsa 1ro5 NO 1 1 NPS NPS 15306017 15306017 Paper says: LasI forms a trimer around a crystallographic threefold axis, but is a monomer in solution (data not shown). 1rob NO 1 1 NPS NPS 15299491 0 -- Annotation transfered from 6rsa 1rom PROBNOT 1 1 NPS NPS 9334748 9334748 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer -- Annotation transfered from 1cmj 1rop NO 2 2 C2 C2 3681971 3681971 Rop is a homodimeric RNA-binding protein (Polisky, 1988) -- Annotation transfered from 1nkd 1rp8 NO 1 1 NPS NPS 16030022 9571044 alpha-Amylases (a-1,4 glucan-4-glucanohydrolase, EC 3.2.1.1) are monomeric enzymes that catalyse the hydrolysis of internal a-D-(1,4) glucosidic linkages in starch and related oligo- and polysaccharides with release of malto-oligosaccharides and glucose in the alpha-anomeric form. - automatic transfer from 1p6w 1rp9 NO 1 1 NPS NPS 16030022 9571044 alpha-Amylases (a-1,4 glucan-4-glucanohydrolase, EC 3.2.1.1) are monomeric enzymes that catalyse the hydrolysis of internal a-D-(1,4) glucosidic linkages in starch and related oligo- and polysaccharides with release of malto-oligosaccharides and glucose in the alpha-anomeric form. - automatic transfer from 1p6w 1rpe PROBNOT 2 2 C2 C2 8355273 8355273 The repressor of phage 434 binds to a set of operator sites as a homodimer. -- Annotation transfered from 1per 1rpf NO 1 1 NPS NPS 7756988 7756988 -- Annotation transfered from 6rsa 1rpg NO 1 1 NPS NPS 7756988 7756988 -- Annotation transfered from 6rsa 1rph NO 1 1 NPS NPS 7756988 7756988 -- Annotation transfered from 6rsa 1rpj PROBNOT 1 1 NPS NPS 10064713 10064713 -- Annotation transfered from 1gub 1rpk NO 1 1 NPS NPS 16030022 9571044 alpha-Amylases (a-1,4 glucan-4-glucanohydrolase, EC 3.2.1.1) are monomeric enzymes that catalyse the hydrolysis of internal a-D-(1,4) glucosidic linkages in starch and related oligo- and polysaccharides with release of malto-oligosaccharides and glucose in the alpha-anomeric form. - automatic transfer from 1p6w 1rpo NO 2 2 C2 C2 7634075 7634075 Rop is a homodimeric RNA-binding protein (Polisky, 1988) -- Annotation transfered from 1nkd 1rpx NO 6 6 D3 D3 10191144 10191144 Paper says hexamer -- interesting family for evolution because interf. very well conserved and there might be monomer, dimer and hexamer. 1rpy NO 2 2 C2 C2 14690593 14690593 Biochemical experiments in vitro and in cells confirm the dimeric nature of the APS SH2 domain and the importance of twin phosphotyrosine recognition in recruitment of APS to the two β subunits of the activated insulin receptor. 1rq0 PROBYES 3 1 NS NPS 15312775 15312775 Paper says nothing about an oligomer - PISA says monomer 1rq2 PROBNOT 2 2 NS NS 15342249 0 Paper seem to give this dimer 1rq7 PROBNOT 2 2 NS NS 15342249 0 Paper seem to give this dimer -- Annotation transfered from 1rq2 1rqc_1 PROBNOT 1 1 NPS NPS 15010544 12005434 BU changed since last release and is now corrected - Paper says: For instance, size-exclusion chromatography on a Superdex 200 HR (Amersham-Pharmacia) column showed numerous peaks corresponding to aggregates containing from one to six PfPDF subunits. Also, dynamic light scattering experiments indicated a high molecular mass, which was hard to determine precisely due to the large polydispersity (data not shown). - Because it is difficult to know which aggregate is right, saying it is a monomer is safer -- monomer oligomer equilibrium - automaticaly inferred from 1jym 1rqc_10 PROBNOT 1 1 NPS NPS 15010544 12005434 BU changed since last release and is now corrected - Paper says: For instance, size-exclusion chromatography on a Superdex 200 HR (Amersham-Pharmacia) column showed numerous peaks corresponding to aggregates containing from one to six PfPDF subunits. Also, dynamic light scattering experiments indicated a high molecular mass, which was hard to determine precisely due to the large polydispersity (data not shown). - Because it is difficult to know which aggregate is right, saying it is a monomer is safer -- monomer oligomer equilibrium - automaticaly inferred from 1jym 1rqc_2 PROBNOT 1 1 NPS NPS 15010544 12005434 BU changed since last release and is now corrected - Paper says: For instance, size-exclusion chromatography on a Superdex 200 HR (Amersham-Pharmacia) column showed numerous peaks corresponding to aggregates containing from one to six PfPDF subunits. Also, dynamic light scattering experiments indicated a high molecular mass, which was hard to determine precisely due to the large polydispersity (data not shown). - Because it is difficult to know which aggregate is right, saying it is a monomer is safer -- monomer oligomer equilibrium - automaticaly inferred from 1jym 1rqc_3 PROBNOT 1 1 NPS NPS 15010544 12005434 BU changed since last release and is now corrected - Paper says: For instance, size-exclusion chromatography on a Superdex 200 HR (Amersham-Pharmacia) column showed numerous peaks corresponding to aggregates containing from one to six PfPDF subunits. Also, dynamic light scattering experiments indicated a high molecular mass, which was hard to determine precisely due to the large polydispersity (data not shown). - Because it is difficult to know which aggregate is right, saying it is a monomer is safer -- monomer oligomer equilibrium - automaticaly inferred from 1jym 1rqc_4 PROBNOT 1 1 NPS NPS 15010544 12005434 BU changed since last release and is now corrected - Paper says: For instance, size-exclusion chromatography on a Superdex 200 HR (Amersham-Pharmacia) column showed numerous peaks corresponding to aggregates containing from one to six PfPDF subunits. Also, dynamic light scattering experiments indicated a high molecular mass, which was hard to determine precisely due to the large polydispersity (data not shown). - Because it is difficult to know which aggregate is right, saying it is a monomer is safer -- monomer oligomer equilibrium - automaticaly inferred from 1jym 1rqc_5 PROBNOT 1 1 NPS NPS 15010544 12005434 BU changed since last release and is now corrected - Paper says: For instance, size-exclusion chromatography on a Superdex 200 HR (Amersham-Pharmacia) column showed numerous peaks corresponding to aggregates containing from one to six PfPDF subunits. Also, dynamic light scattering experiments indicated a high molecular mass, which was hard to determine precisely due to the large polydispersity (data not shown). - Because it is difficult to know which aggregate is right, saying it is a monomer is safer -- monomer oligomer equilibrium - automaticaly inferred from 1jym 1rqc_6 PROBNOT 1 1 NPS NPS 15010544 12005434 BU changed since last release and is now corrected - Paper says: For instance, size-exclusion chromatography on a Superdex 200 HR (Amersham-Pharmacia) column showed numerous peaks corresponding to aggregates containing from one to six PfPDF subunits. Also, dynamic light scattering experiments indicated a high molecular mass, which was hard to determine precisely due to the large polydispersity (data not shown). - Because it is difficult to know which aggregate is right, saying it is a monomer is safer -- monomer oligomer equilibrium - automaticaly inferred from 1jym 1rqc_7 PROBNOT 1 1 NPS NPS 15010544 12005434 BU changed since last release and is now corrected - Paper says: For instance, size-exclusion chromatography on a Superdex 200 HR (Amersham-Pharmacia) column showed numerous peaks corresponding to aggregates containing from one to six PfPDF subunits. Also, dynamic light scattering experiments indicated a high molecular mass, which was hard to determine precisely due to the large polydispersity (data not shown). - Because it is difficult to know which aggregate is right, saying it is a monomer is safer -- monomer oligomer equilibrium - automaticaly inferred from 1jym 1rqc_8 PROBNOT 1 1 NPS NPS 15010544 12005434 BU changed since last release and is now corrected - Paper says: For instance, size-exclusion chromatography on a Superdex 200 HR (Amersham-Pharmacia) column showed numerous peaks corresponding to aggregates containing from one to six PfPDF subunits. Also, dynamic light scattering experiments indicated a high molecular mass, which was hard to determine precisely due to the large polydispersity (data not shown). - Because it is difficult to know which aggregate is right, saying it is a monomer is safer -- monomer oligomer equilibrium - automaticaly inferred from 1jym 1rqc_9 PROBNOT 1 1 NPS NPS 15010544 12005434 BU changed since last release and is now corrected - Paper says: For instance, size-exclusion chromatography on a Superdex 200 HR (Amersham-Pharmacia) column showed numerous peaks corresponding to aggregates containing from one to six PfPDF subunits. Also, dynamic light scattering experiments indicated a high molecular mass, which was hard to determine precisely due to the large polydispersity (data not shown). - Because it is difficult to know which aggregate is right, saying it is a monomer is safer -- monomer oligomer equilibrium - automaticaly inferred from 1jym 1rqg NO 2 2 C2 C2 14992601 14992601 Paper says: methionyl-tRNA synthetases (MetRS) are homodimers or monomers depending on the presence or absence of a domain appended at the C-side of the polypeptide chain -- interesting example where an extra bit of sequence is required for dimerization. 1rqi NO 2 2 C2 C2 14672944 14672944 Interface geometry conserved with 1uby (27% id) 1rqj_1 PROBYES 1 2 NPS C2 14672944 14672944 BU changed since last release and is now incorrect - Interface geometry conserved with 1uby (27% id) - automaticaly inferred from 1rqi 1rqj_2 PROBYES 1 2 NPS C2 14672944 14672944 BU changed since last release and is now incorrect - Interface geometry conserved with 1uby (27% id) - automaticaly inferred from 1rqi 1rqw NO 1 1 NPS NPS 0 0 Thaumatin is a stable monomeric protein of 22kDa -- Annotation transfered from 1thu 1rr6 PROBNOT 3 3 C3 C3 14982926 14706628 BU changed since last release and is now corrected - Paper says trimer - automaticaly inferred from 1rct 1rra NA 1 1 NPS NPS 10090281 10090281 Rat RNAase A. They seem to refer to a dimer at some point in the paper but it is not clear 1rrf PROBNOT 1 1 NPS NPS 7552752 7552752 Might form a dimer when anchored to the membrane but is monomeric in solution 1rrg PROBYES 2 1 C2 NPS 7552752 7552752 Might form a dimer when anchored to the membrane but is monomeric in solution 1rrm NO 2 2 C2 C2 0 0 Interfave geometry conserved with 1vhd (31%) 1rro PROBNOT 1 1 NPS NPS 8487302 8487302 Similar structures are either monomers or weak dimers - Paper does not mention dimer - PISA says monomer -- Annotation transfered from 1omd 1rrx PROBNOT 1 1 NPS NPS 15122645 15122645 1rs6 NO 2 2 C2 C2 15122883 15122883 Clear dimer -- Annotation transfered from 1m00 1rs7 NO 2 2 C2 C2 15122883 15122883 Clear dimer -- Annotation transfered from 1m00 1rs8 NO 2 2 C2 C2 15122883 15122883 Clear dimer -- Annotation transfered from 1fol 1rs9 NO 2 2 C2 C2 15122883 15122883 Clear dimer -- Annotation transfered from 1fol 1rsc NA 16 16 D4 D4 7922027 7922027 BU changed since last release and is now corrected - -- PISA cannot reconstruct it, I see only 8 chains, I dont understand -- Annotation transfered from 1rbl 1rse NO 1 1 NPS NPS 8794773 8794773 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1rsm NO 1 1 NPS NPS 3936036 3936036 -- Annotation transfered from 6rsa 1rsn_1 PROBNOT 1 1 NPS NPS 8396032 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1rsn_2 PROBNOT 1 1 NPS NPS 8396032 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1rst NO 4 4 D2 D2 8636976 8636976 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1rsu NO 4 4 D2 D2 8636976 8636976 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1rsy PROBNOT 1 1 NPS NPS 7697723 7697723 PISA says monomer 1rsz PROBNOT 3 3 C3 C3 0 14706628 BU changed since last release and is now corrected - Paper says trimer - automaticaly inferred from 1rct 1rt9 PROBNOT 3 3 C3 C3 0 14706628 BU changed since last release and is now corrected - Paper says trimer - automaticaly inferred from 1rct 1rta NO 1 1 NPS NPS 1429575 1429575 -- Annotation transfered from 6rsa 1rtb NO 1 1 NPS NPS 1429575 1429575 -- Annotation transfered from 6rsa 1rtc PROBNOT 1 1 NPS NPS 8453380 8453380 Blocked ricin undergoes a pH-dependent reversible self-association, being predominantly dimeric at neutral pH and monomeric at acidic pH. -- Annotation transfered from 1apg 1rte_1 NA 1 2 NPS C2 15122887 11483493 BU changed since last release and is now incorrect - Gel filtration analysis of the recombinant protein suggested that trHbN has a dimeric assembly (Couture et al., 1999a). --> probably not open, but PISA doesnt find the right one. - automaticaly inferred from 1idr 1rte_2 NA 1 2 NPS C2 15122887 11483493 BU changed since last release and is now incorrect - Gel filtration analysis of the recombinant protein suggested that trHbN has a dimeric assembly (Couture et al., 1999a). --> probably not open, but PISA doesnt find the right one. - automaticaly inferred from 1idr 1rtg PROBNOT 1 1 NPS NPS 8549817 8549817 Fragment - paper says nothing, PISA says monomer -- Annotation transfered from 1gen 1rtp_1 PROBNOT 1 1 NPS NPS 8289291 15287728 Similar structures are either monomers or weak dimers - Paper does not mention dimer - PISA says monomer - automatic transfer from 1s3p 1rtp_2 PROBNOT 1 1 NPS NPS 8289291 15287728 Similar structures are either monomers or weak dimers - Paper does not mention dimer - PISA says monomer - automatic transfer from 1s3p 1rtp_3 PROBNOT 1 1 NPS NPS 8289291 15287728 Similar structures are either monomers or weak dimers - Paper does not mention dimer - PISA says monomer - automatic transfer from 1s3p 1rtq NO 1 1 NPS NPS 16596389 16596389 Aminopeptidase from Aeromonas proteolytica (AAP) is a small, monomeric enzyme (32KDa) -- Annotation transfered from 1cp6 1rtr NO 2 2 C2 C2 14672944 14672944 Interface geometry conserved with 1uby (27% id) 1rts NO 2 2 C2 C2 9894005 9894005 SP says dimer 1rtt YES 1 2 NPS C2 16552139 16552139 Said in paper 1rtv YES 2 2 NS C2 0 0 Interface geometry conserved with 1dzr (65%) 1rtz PROBNOT 1 1 NPS NPS 14769023 14769023 EcoCyc & SP say monomer. -- Annotation transfered from 1eqm 1ru2 PROBNOT 1 1 NPS NPS 14769023 14769023 EcoCyc & SP say monomer. -- Annotation transfered from 1eqm 1rus NO 2 2 C2 C2 2492987 2492987 Paper says: In contrast to the hexadecameric plant enzyme, ribulose-P2 carboxylase from Rhodospirillum rubrum is a dimer of only large subunits. 1ruv NO 1 1 NPS NPS 15299932 0 -- Annotation transfered from 6rsa 1rv1 YES 3 1 NS NPS 14704432 14704432 Paper doesnt mention a dimer and PISA says monomer - given the protein it makes sence (this is just a fragment and it bind a peptide on p53 which is a big tetramer so it is unlikely that the two geometries match) -- very interesting example in which a protein interaction is prevented by a small molecule. 1rv3 NO 4 4 D2 D2 15170323 15170323 Paper describes a tetramer, SP and PISA agree. -- Annotation transfered from 1rv4 1rv4 NO 4 4 D2 D2 15170323 15170323 Paper describes a tetramer, SP and PISA agree. 1rvd NO 1 1 NPS NPS 10359839 10359839 Ras proteins are monomeric G proteins -- Annotation transfered from 1ctq 1rvu NO 4 4 D2 D2 15170323 15170323 Paper describes a tetramer, SP and PISA agree. -- Annotation transfered from 1rv4 1rvy NO 4 4 D2 D2 15170323 15170323 Paper describes a tetramer, SP and PISA agree. -- Annotation transfered from 1rv4 1rw0 PROBYES 2 1 C2 NPS 0 0 No paper - Similar protein is monomeric and PISA says monomer 1rw3 NO 1 1 NPS NPS 15130474 9545316 Active as a monomer - Although HIV RT is active as a dimer (see ref) 1rw7 NO 2 2 C2 C2 14745011 14745011 found to be dimeric in solution (said in the paper) - interface completely different from the ones in the D3 protein 1g2i. - also different from 1ons. -- Annotation transfered from 1qvz 1rwq NO 2 2 C2 C2 15006388 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 1rwy_1 PROBNOT 1 1 NPS NPS 15169955 15287728 Similar structures are either monomers or weak dimers - Paper does not mention dimer - PISA says monomer - automatic transfer from 1s3p 1rwy_2 PROBNOT 1 1 NPS NPS 15169955 15287728 Similar structures are either monomers or weak dimers - Paper does not mention dimer - PISA says monomer - automatic transfer from 1s3p 1rwy_3 PROBNOT 1 1 NPS NPS 15169955 15287728 Similar structures are either monomers or weak dimers - Paper does not mention dimer - PISA says monomer - automatic transfer from 1s3p 1rwz NO 3 3 C3 C3 14718165 14718165 -- Annotation transfered from 1rxm 1rx1 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1rx2 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1rx3 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1rx4 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1rx5 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1rx6 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1rx7 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1rx8 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1rx9 PROBNOT 1 1 NPS NPS 9012674 9012674 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 1rxc_1 NO 6 6 D3 D3 15003451 15003451 Interface geometry conserved with 1q1g (28%) - automatic transfer from 1rxy 1rxc_2 NO 6 6 D3 D3 15003451 15003451 Interface geometry conserved with 1q1g (28%) - automatic transfer from 1rxy 1rxf PROBNOT 3 3 C3 C3 9723623 9723623 this suggests that the trimeric structure of the apoenzyme found in the crystal might have some functional significance, for example in the protection of the C-terminal arm (rich in lysines and arginines) against proteases in the apo- or resting forms of DAOCS. However, DAOCS dissociates into monomers in the presence of Fe(II) and 2-oxoglutarate. -- Annotation transfered from 1uog 1rxg PROBNOT 3 3 C3 C3 9723623 9723623 this suggests that the trimeric structure of the apoenzyme found in the crystal might have some functional significance, for example in the protection of the C-terminal arm (rich in lysines and arginines) against proteases in the apo- or resting forms of DAOCS. However, DAOCS dissociates into monomers in the presence of Fe(II) and 2-oxoglutarate. -- Annotation transfered from 1uog 1rxh NO 4 4 D2 D2 15079055 15079055 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1rxj NO 4 4 D2 D2 15079055 15079055 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1rxk NO 4 4 D2 D2 15079055 15079055 1rxm NO 3 3 C3 C3 14718165 14718165 1rxp PROBNOT 1 1 NPS NPS 15081015 15081015 -- Annotation transfered from 1az8 1rxu_1 NO 6 6 D3 D3 15003451 15003451 Interface geometry conserved with 1q1g (28%) - automatic transfer from 1rxy 1rxu_2 NO 6 6 D3 D3 15003451 15003451 Interface geometry conserved with 1q1g (28%) - automatic transfer from 1rxy 1rxu_3 NO 6 6 D3 D3 15003451 15003451 Interface geometry conserved with 1q1g (28%) - automatic transfer from 1rxy 1rxv_1 PROBNOT 1 1 NPS NPS 14718165 14718165 Flap EndoNuclease-1 (FEN-1) and the processivity factor proliferating cell nuclear antigen (PCNA) are central to DNA replication and repair. PCNA forms a trimer but it seems that FEN-1 doesnt. - automatic transfer from 1rxw 1rxv_2 PROBNOT 1 1 NPS NPS 14718165 14718165 Flap EndoNuclease-1 (FEN-1) and the processivity factor proliferating cell nuclear antigen (PCNA) are central to DNA replication and repair. PCNA forms a trimer but it seems that FEN-1 doesnt. - automatic transfer from 1rxw 1rxw PROBNOT 1 1 NPS NPS 14718165 14718165 Flap EndoNuclease-1 (FEN-1) and the processivity factor proliferating cell nuclear antigen (PCNA) are central to DNA replication and repair. PCNA forms a trimer but it seems that FEN-1 doesnt. 1rxy NO 6 6 D3 D3 15003451 15003451 Interface geometry conserved with 1q1g (28%) 1rxz NO 3 3 C3 C3 14718165 14718165 -- Annotation transfered from 1rxm 1ry0_1 PROBNOT 1 1 NPS NPS 14979715 14996743 PISA says it is a monomer, and relative are too. - automatic transfer from 1s1r 1ry0_2 PROBNOT 1 1 NPS NPS 14979715 14996743 PISA says it is a monomer, and relative are too. - automatic transfer from 1s1r 1ry2 YES 3 3 C3 C3 14769018 14769018 Good annotation but wrong assembly - Paper says trimer 1ry6 NO 1 1 NPS NPS 15029249 0 Missing dimerization coil-coil 1ry8_1 PROBNOT 1 1 NPS NPS 14979715 14996743 PISA says it is a monomer, and relative are too. - automatic transfer from 1s1r 1ry8_2 PROBNOT 1 1 NPS NPS 14979715 14996743 PISA says it is a monomer, and relative are too. - automatic transfer from 1s1r 1ryc PROBNOT 1 1 NPS NPS 8673607 8673607 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1ryd NO 4 4 D2 D2 0 11705375 BU changed since last release and is now corrected - Interface geometry conserved with 1tlt (20%) - automatic transfer from 1h6b 1rye PROBYES 4 4 C2 D2 0 11705375 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - Interface geometry conserved with 1tlt (20%) - automaticaly inferred from 1h6b 1ryt NO 2 2 C2 C2 8646540 8646540 -- Annotation transfered from 1lkm 1ryw_1 PROBYES 4 1 D2 NPS 15531591 10823915 BU changed since last release and is now incorrect - MurA crystallizes from PEG 20000 as a monomeric species. - automaticaly inferred from 1eyn 1ryw_2 PROBYES 4 1 D2 NPS 15531591 10823915 BU changed since last release and is now incorrect - MurA crystallizes from PEG 20000 as a monomeric species. - automaticaly inferred from 1eyn 1ryz PROBYES 6 6 NS D3 0 15003451 BU changed since last release and is now incorrect - Interface geometry conserved with 1q1g (28%) - automaticaly inferred from 1rxy 1rza PROBNOT 1 1 NPS NPS 15299481 0 9000633 says monomeric -- Annotation transfered from 1uga 1rzb PROBNOT 1 1 NPS NPS 15299481 0 9000633 says monomeric -- Annotation transfered from 1uga 1rzc PROBNOT 1 1 NPS NPS 15299481 0 9000633 says monomeric -- Annotation transfered from 1uga 1rzd PROBNOT 1 1 NPS NPS 15299481 0 9000633 says monomeric -- Annotation transfered from 1uga 1rze PROBNOT 1 1 NPS NPS 15299481 0 9000633 says monomeric -- Annotation transfered from 1uga 1rzl NA 2 1 C2 NPS 9512714 9512714 Paper does not mention a dimer but PISA says dimer 1rzm NO 4 4 D2 D2 15276836 15276836 SP says tetramer 1rzp NO 3 3 C3 C3 15003518 15003518 -- Annotation transfered from 2nrd 1rzq NO 3 3 C3 C3 15003518 15003518 -- Annotation transfered from 2nrd 1rzx PROBNOT 1 1 NPS NPS 15023337 15023337 Paper says nothing, PISA says monomer and related proteins are monomeric 1s01 NO 1 1 NPS NPS 2684274 2684274 -- Annotation transfered from 1yja 1s02 NO 1 1 NPS NPS 2127106 2127106 -- Annotation transfered from 1yja 1s06 NO 2 2 C2 C2 14756557 14756557 Paper says dimer -- Annotation transfered from 1mly 1s07 NO 2 2 C2 C2 14756557 14756557 Paper says dimer -- Annotation transfered from 1mly 1s08 NO 2 2 C2 C2 14756557 14756557 Paper says dimer -- Annotation transfered from 1mly 1s09 NO 2 2 C2 C2 14756557 14756557 Paper says dimer -- Annotation transfered from 1mly 1s0a NO 2 2 C2 C2 14756557 14756557 Paper says dimer -- Annotation transfered from 1mly 1s0l PROBNOT 1 1 NPS NPS 15663946 15663946 SP says monomer -- Annotation transfered from 21bi 1s0q PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1az8 1s0r PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1az8 1s0u NO 1 1 NPS NPS 14688270 14688270 Same heterotrimeric complex as 1kk1. 1s0x NO 1 1 NPS NPS 14722075 14722075 Paper says: RORα LBD was shown to run as a monomer on native gels and by size exclusion chromatography (data not shown). -- Annotation transfered from 1n83 1s0z PROBNOT 1 1 NPS NPS 15055995 15055995 paper says nothing, PISA says monomer -- Annotation transfered from 1ie9 1s17_1 PROBNOT 1 1 NPS NPS 15006385 12126617 Paper says nothing although gel filtration mentioned. Related proteins are monomeric and PISA says monomer - automatic transfer from 1lry 1s17_2 PROBNOT 1 1 NPS NPS 15006385 12126617 Paper says nothing although gel filtration mentioned. Related proteins are monomeric and PISA says monomer - automatic transfer from 1lry 1s19 PROBNOT 1 1 NPS NPS 15055995 15055995 paper says nothing, PISA says monomer -- Annotation transfered from 1ie9 1s1a NO 2 2 C2 C2 0 12595543 Implied in paper that it is a dimer, PISA also says that - automatic transfer from 1n3q 1s1e PROBYES 1 2 NPS C2 14980207 14980206 BU changed since last release and is now incorrect - The whole complex is a dimer both in solution and in the crystal. - automaticaly inferred from 1s6c 1s1g NO 4 4 C4 C4 14980207 14980207 Interface geometry conserved with 1t1d (37%) 1s1j PROBYES 2 1 NS NPS 15006376 10880432 No oligomer mentioned - PISA says monomer -- Annotation transfered from 1f46 1s1p PROBNOT 1 1 NPS NPS 14996743 14996743 PISA says it is a monomer, and relative are too. -- Annotation transfered from 1s1r 1s1r PROBNOT 1 1 NPS NPS 14996743 14996743 PISA says it is a monomer, and relative are too. 1s1y PROBNOT 1 1 NPS NPS 15274923 15274923 SP says monomer -- Annotation transfered from 1s1z 1s1z PROBNOT 1 1 NPS NPS 15274923 15274923 SP says monomer 1s22 NO 1 1 NPS NPS 14961632 14961632 Actin exists in different states -- Annotation transfered from 1j6z 1s2a PROBNOT 1 1 NPS NPS 14996743 14996743 PISA says it is a monomer, and relative are too. -- Annotation transfered from 1s1r 1s2c PROBNOT 1 1 NPS NPS 14996743 14996743 PISA says it is a monomer, and relative are too. -- Annotation transfered from 1s1r 1s2p PROBNOT 2 2 C2 C2 14993674 0 SP says: Oligomer; Can form dimers (beta-crustacyanin); or complexes of 16 subunits (alpha-crustacyanin). There are five types of subunits: A1, A2, A3, C1 and C2 1s2q NO 2 2 C2 C2 15027868 15027868 Paper says dimer -- Annotation transfered from 1gos 1s2t NO 4 4 D2 D2 15078090 15078090 Paper and SP say tetramer -- Annotation transfered from 1m1b 1s2u NO 4 4 D2 D2 15078090 15078090 Paper and SP say tetramer -- Annotation transfered from 1m1b 1s2v NO 4 4 D2 D2 15078090 15078090 Paper and SP say tetramer -- Annotation transfered from 1m1b 1s2w YES 1 2 NPS C2 15078090 15078090 This assembly might not be physiologicaly relevant. As paper says: yet it is not known whether a dimeric subassembly is a functional form of the enzyme. Moreover, the high-salt crystal form may be physiologically irrelevant because the substrate and product are highly charged and high ionic strength may reduce their binding affinity. -- interesting case of difference in QS according to difference in salt concentration 1s2y NO 2 2 C2 C2 15027868 15027868 Paper says dimer -- Annotation transfered from 1gos 1s2z YES 1 2 NPS C2 15134924 15134924 Homodimeric protein -- Annotation transfered from 1s30 1s30 YES 1 2 NPS C2 15134924 15134924 Homodimeric protein 1s36 PROBNOT 1 1 NPS NPS 15155735 12755603 Paper does not mention a dimer - PISA says monomer - automatic transfer from 1jf2 1s3b NO 2 2 C2 C2 15027868 15027868 Paper says dimer -- Annotation transfered from 1gos 1s3e NO 2 2 C2 C2 15027868 15027868 Paper says dimer -- Annotation transfered from 1gos 1s3g PROBNOT 1 1 NPS NPS 15100224 15100224 1s3o PROBYES 2 4 C2 D2 15133161 15133161 Given 3ull, this one is probably an error. 1s3p PROBNOT 1 1 NPS NPS 15287728 15287728 Similar structures are either monomers or weak dimers - Paper does not mention dimer - PISA says monomer 1s3t NO 9 9 C3 C3 15038715 15038715 Interface geometry conserved with 1ejs (64% id avg) -- Annotation transfered from 1ubp 1s3u PROBNOT 1 1 NPS NPS 15039552 15039552 1s3v PROBNOT 1 1 NPS NPS 15039552 15039552 -- Annotation transfered from 1s3u 1s3w PROBNOT 1 1 NPS NPS 15039552 15039552 -- Annotation transfered from 1s3u 1s3y PROBNOT 1 1 NPS NPS 15039552 15039552 PISA also says monomer - Human is monomeric so I guess it should be - Only Thermogota seems to be dimeric -- Annotation transfered from 1cd2 1s3z NO 2 2 C2 C2 15123251 15123251 Domain Swapped dimer - similar to 1qsm (no detectable seq id?!) -- good example of conservation and evolution, also because 1qsm is a tetramer -- Annotation transfered from 1s60 1s44 PROBNOT 2 2 C2 C2 14993674 14993674 SP says: Oligomer; Can form dimers (beta-crustacyanin); or complexes of 16 subunits (alpha-crustacyanin). There are five types of subunits: A1, A2, A3, C1 and C2 -- Annotation transfered from 1s2p 1s46 NO 1 1 NPS NPS 15023061 0 9882648 says: Under both native and denaturing conditions, the molecular mass obtained was 70 ± 2 kDa (Fig. 3B). This result demonstrates the monomeric structure of the amylosucrase from N. polysaccharea -- Annotation transfered from 1mw1 1s4m_1 PROBNOT 1 1 NPS NPS 15468322 12910462 BU changed since last release and is now corrected - Enzyme, no reason for that type of interaction, plus this is a thermophile. - automaticaly inferred from 1mrz 1s4m_2 PROBNOT 1 1 NPS NPS 15468322 12910462 BU changed since last release and is now corrected - Enzyme, no reason for that type of interaction, plus this is a thermophile. - automaticaly inferred from 1mrz 1s4q PROBNOT 1 1 NPS NPS 0 0 No paper, PISA says monomer 1s4r PROBNOT 1 1 NPS NPS 15041745 15041745 SP says monomer -- Annotation transfered from 1s1z 1s4s PROBNOT 1 1 NPS NPS 15041745 15041745 SP says monomer -- Annotation transfered from 1s1z 1s51_1 YES 1 3 NPS C3 14982414 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1s51_2 YES 1 3 NPS C3 14982414 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1s52_1 YES 1 3 NPS C3 14982414 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1s52_2 YES 1 3 NPS C3 14982414 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1s53_1 YES 1 3 NPS C3 14982414 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1s53_2 YES 1 3 NPS C3 14982414 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1s54_1 YES 1 3 NPS C3 14982414 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1s54_2 YES 1 3 NPS C3 14982414 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1s55 PROBNOT 3 3 C3 C3 0 11581298 SP says trimer - automatic transfer from 1jtz 1s56_1 NA 1 2 NPS C2 15016811 11483493 BU changed since last release and is now incorrect - Gel filtration analysis of the recombinant protein suggested that trHbN has a dimeric assembly (Couture et al., 1999a). --> probably not open, but PISA doesnt find the right one. - automaticaly inferred from 1idr 1s56_2 NA 1 2 NPS C2 15016811 11483493 BU changed since last release and is now incorrect - Gel filtration analysis of the recombinant protein suggested that trHbN has a dimeric assembly (Couture et al., 1999a). --> probably not open, but PISA doesnt find the right one. - automaticaly inferred from 1idr 1s5k NO 2 2 C2 C2 15123251 15123251 Domain Swapped dimer - similar to 1qsm (no detectable seq id?!) -- good example of conservation and evolution, also because 1qsm is a tetramer -- Annotation transfered from 1s60 1s5m NO 4 4 D2 D2 15157080 15157080 1s5n NO 4 4 D2 D2 15157080 15157080 -- Annotation transfered from 1s5m 1s5p PROBNOT 1 1 NPS NPS 15019790 15019790 1s5s PROBNOT 1 1 NPS NPS 15005618 0 -- Annotation transfered from 1qqu 1s5t NO 4 4 D2 D2 15066435 15066435 Interface geometry conserved with 1fdy (25%) -- interesting QS evolution: interface geometry of these two proteins from e coli is conserved while the geometry with other proteins (closer in seq % id but from other organisms) is not. -- Annotation transfered from 1s5w 1s5v NO 4 4 D2 D2 15066435 15066435 Interface geometry conserved with 1fdy (25%) -- interesting QS evolution: interface geometry of these two proteins from e coli is conserved while the geometry with other proteins (closer in seq % id but from other organisms) is not. -- Annotation transfered from 1s5w 1s5w NO 4 4 D2 D2 15066435 15066435 Interface geometry conserved with 1fdy (25%) -- interesting QS evolution: interface geometry of these two proteins from e coli is conserved while the geometry with other proteins (closer in seq % id but from other organisms) is not. 1s5z NO 6 6 D3 D3 16787337 11277918 BU changed since last release and is now corrected - Paper says hexamer - automatic transfer from 1hhq 1s60 NO 2 2 C2 C2 15123251 15123251 Domain Swapped dimer - similar to 1qsm (no detectable seq id?!) -- good example of conservation and evolution, also because 1qsm is a tetramer 1s61_1 NA 1 2 NPS C2 15016811 11483493 BU changed since last release and is now incorrect - Gel filtration analysis of the recombinant protein suggested that trHbN has a dimeric assembly (Couture et al., 1999a). --> probably not open, but PISA doesnt find the right one. - automaticaly inferred from 1idr 1s61_2 NA 1 2 NPS C2 15016811 11483493 BU changed since last release and is now incorrect - Gel filtration analysis of the recombinant protein suggested that trHbN has a dimeric assembly (Couture et al., 1999a). --> probably not open, but PISA doesnt find the right one. - automaticaly inferred from 1idr 1s6c NO 2 2 C2 C2 14980206 14980206 The whole complex is a dimer both in solution and in the crystal. 1s6f PROBNOT 1 1 NPS NPS 15005618 0 -- Annotation transfered from 1qqu 1s6h PROBNOT 1 1 NPS NPS 15005618 0 -- Annotation transfered from 1qqu 1s6r PROBNOT 1 1 NPS NPS 14521155 0 This is a class C beta Lactamase and those are monomeric (12951239) -- Annotation transfered from 1c3b -- Annotation transfered from 1ga0 1s6z NO 1 1 NPS NPS 15078092 15078092 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 1s73 PROBNOT 1 1 NPS NPS 0 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 1s7c NO 4 4 D2 D2 0 0 SP says tetramer - papers too 1s7g PROBYES 5 1 NS NPS 15023335 15023335 They seem to imply that it is a monomer 1s7o YES 3 2 NS C2 15213388 0 Paper says: Since the dynamic light scattering showed only one peak at a protein concentration of about 1 mg ml-1 with a polydispersity of 20%, we assume that the protein sample is monodisperse in its dimeric state. This is further supported by the extensive buried contact surface between two monomers observed in the crystal structure. 1s7z YES 2 2 NS C2 11804597 11804597 Paper says: The dimer formed by ocr in solution is retained in the crystal with perfect crystallographic 2-fold symmetry 1s80 NO 6 6 D3 D3 15333931 0 Paper says: The quaternary structure of all known hexapeptide acyltransferases is trimeric with the exception of SAT, which had been predicted to adopt a hexameric structure, based on equilibrium sedimentation studies and the appearance of electron micrographs of negatively stained particles -- Annotation transfered from 1sst 1s81 PROBNOT 1 1 NPS NPS 15005618 0 -- Annotation transfered from 1qqu 1s82 PROBNOT 1 1 NPS NPS 15005618 0 -- Annotation transfered from 1qqu 1s83 PROBNOT 1 1 NPS NPS 15005618 0 -- Annotation transfered from 1qqu 1s84 PROBNOT 1 1 NPS NPS 15005618 0 -- Annotation transfered from 1qqu 1s85 PROBNOT 1 1 NPS NPS 15005618 0 -- Annotation transfered from 1qqu 1s8g NO 1 1 NPS NPS 15596433 15596433 Paper: ACL myotoxin presents a monomer in the asymmetric unit of all three crystal forms described here, and this monomeric behavior is consistent with dynamic light scattering analysis carried out in solution under the crystallization conditions used here. - still they say that related proteins (Lys49-PLA2 myotoxins) are dimeric. -- Annotation transfered from 1s8i 1s8h NO 1 1 NPS NPS 15596433 15596433 Paper: ACL myotoxin presents a monomer in the asymmetric unit of all three crystal forms described here, and this monomeric behavior is consistent with dynamic light scattering analysis carried out in solution under the crystallization conditions used here. - still they say that related proteins (Lys49-PLA2 myotoxins) are dimeric. -- Annotation transfered from 1s8i 1s8i NO 1 1 NPS NPS 15596433 15596433 Paper: ACL myotoxin presents a monomer in the asymmetric unit of all three crystal forms described here, and this monomeric behavior is consistent with dynamic light scattering analysis carried out in solution under the crystallization conditions used here. - still they say that related proteins (Lys49-PLA2 myotoxins) are dimeric. 1s8j PROBNOT 1 1 NPS NPS 15109251 15109251 PISA does not find the trimer so the trimeric contacts probably do not exist. -- Annotation transfered from 1brd 1s8l PROBNOT 1 1 NPS NPS 15109251 15109251 PISA does not find the trimer so the trimeric contacts probably do not exist. -- Annotation transfered from 1brd 1s8n NO 1 1 NPS NPS 15341725 15341725 Paper says monomer -- Annotation transfered from 1sd5 1s96 PROBNOT 2 2 C2 C2 0 0 SP says: Homotetramer (under low ionic conditions) or homodimer (under high ionic conditions). 1s9p_1 NO 2 2 C2 C2 15161930 11864604 Paper says dimer - automatic transfer from 1kv6 1s9p_2 NO 2 2 C2 C2 15161930 11864604 Paper says dimer - automatic transfer from 1kv6 1s9q NO 2 2 C2 C2 15161930 15161930 Paper says dimer -- Annotation transfered from 1kv6 1sar_1 PROBNOT 1 1 NPS NPS 1654932 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1sar_2 PROBNOT 1 1 NPS NPS 1654932 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1sav PROBNOT 1 1 NPS NPS 1311770 1311770 11099380SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1avr 1say NO 6 6 D3 D3 9665169 9665169 Paper says hexameric 1sb7 PROBYES 2 1 NS NPS 15208439 15208439 Oligomer not mentioned 1sb8 NO 2 2 C2 C2 15016816 15016816 Paper says dimer -- Annotation transfered from 1sb9 1sb9 NO 2 2 C2 C2 15016816 15016816 Paper says dimer 1sbc NO 1 1 NPS NPS 3150541 3150541 -- Annotation transfered from 1be6 1sbd PROBNOT 4 4 D2 D2 9398234 9398234 1sbe PROBNOT 4 4 D2 D2 9398234 9398234 -- Annotation transfered from 1sbd 1sbf PROBNOT 4 4 D2 D2 9398234 9398234 -- Annotation transfered from 1sbd 1sbg NO 2 2 C2 C2 7918383 7918383 -- Annotation transfered from 1ajx 1sbh NO 1 1 NPS NPS -1 0 -- Annotation transfered from 1yja 1sbi NO 1 1 NPS NPS -1 0 -- Annotation transfered from 1yja 1sbk NA 4 2 D2 C2 0 0 No info (struct genomics), PISA says dimer but interface geometry conserved with 1q4u (30% seq sim). 1sbm PROBNOT 1 1 NPS NPS 0 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 1sbt NO 1 1 NPS NPS 5160720 5160720 -- Annotation transfered from 1yja 1sbw PROBNOT 1 1 NPS NPS 10447205 10447205 -- Annotation transfered from 1az8 1sby NO 2 2 C2 C2 0 9735295 Paper says dimer - automatic transfer from 1a4u 1sc8 PROBNOT 1 1 NPS NPS 15150279 15150279 -- Annotation transfered from 1owd 1sc9 NO 2 2 C2 C2 14998991 14998991 PISA, SP, paper and I say homodimer 1sca NO 1 1 NPS NPS 8378343 8378343 -- Annotation transfered from 1be6 1scb NO 1 1 NPS NPS 8378343 8378343 -- Annotation transfered from 1be6 1scd NO 1 1 NPS NPS 8297378 8297378 -- Annotation transfered from 1be6 1sce PROBYES 4 2 C2 C2 7479758 7479758 Paper says: However, the 1B-interchanged sucl can be purified as a dimer, and no molecular assemblies larger than dimer or weak tetramer were observed by gel filtration experiments for sucl from fission yeast. 1sci NO 2 2 C2 C2 14998991 14998991 PISA, SP, paper and I say homodimer -- Annotation transfered from 1sc9 1sck NO 2 2 C2 C2 14998991 14998991 PISA, SP, paper and I say homodimer -- Annotation transfered from 1sc9 1scn NO 1 1 NPS NPS 8068694 8068694 -- Annotation transfered from 1be6 1scq NO 2 2 C2 C2 14998991 14998991 PISA, SP, paper and I say homodimer -- Annotation transfered from 1sc9 1scr NO 4 4 D2 D2 15299372 0 SP says tetramer -- Annotation transfered from 1cjp 1scs NO 4 4 D2 D2 15299372 0 SP says tetramer -- Annotation transfered from 1cjp 1scw PROBNOT 1 1 NPS NPS 15170342 15170342 the Streptomyces R61 and Actinomadura R39 DD-peptidases, are water-soluble monomeric proteins; (12723972) -- Annotation transfered from 1pwd 1scz NO 24 24 Octa Octa 0 0 BU changed since last release and is now corrected - Bad reconstruction - Clear 24-mer 1sd0 NO 1 1 NPS NPS 15236576 15236576 Paper says: Arginine kinase is widespread in invertebrates and may be the primordial enzyme because of its widely available substrate, monomeric structure, and presence in protozoa -- interesting: very good family for QS evolution (close monomer, dimer and octamer) -- Annotation transfered from 1p52 1sd1 NO 3 3 C3 C3 15122881 15122881 Interface conserved with 1v48 (27%) -- Annotation transfered from 1cg6 1sd2 NO 3 3 C3 C3 15122881 15122881 Interface conserved with 1v48 (27%) -- Annotation transfered from 1cg6 1sd5 NO 1 1 NPS NPS 15341725 15341725 Paper says monomer 1sda_1 NO 2 2 C2 C2 1444476 1619651 PAper, SP say dimer - automatic transfer from 1cob 1sda_2 NO 2 2 C2 C2 1444476 1619651 PAper, SP say dimer - automatic transfer from 1cob 1sde PROBNOT 1 1 NPS NPS 15170342 15581896 the Streptomyces R61 and Actinomadura R39 DD-peptidases, are water-soluble monomeric proteins; (12723972) - automatic transfer from 1pwd 1sdj YES 1 2 NPS C2 15545603 15545603 Paper says dimer 1sdm NO 1 1 NPS NPS 14988396 0 Missing dimerization coil-coil 1sdq PROBNOT 1 1 NPS NPS 0 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 1sdt NO 2 2 C2 C2 15066177 15066177 -- Annotation transfered from 1ajx 1sdu NO 2 2 C2 C2 15066177 15066177 -- Annotation transfered from 1ajx 1sdv NO 2 2 C2 C2 15066177 15066177 -- Annotation transfered from 1ajx 1sdy YES 4 2 NS C2 1772629 1772629 SOD is a dimer 1sdz PROBNOT 1 1 NPS NPS 15107838 15107838 Fragment of a bigger protein - no BIR1 dimer mentioned 1se0 PROBNOT 1 1 NPS NPS 15107838 0 Fragment of a bigger protein - no BIR1 dimer mentioned -- Annotation transfered from 1sdz 1se2 PROBNOT 1 1 NPS NPS 7552730 7552730 dimer not mentioned in literature, PISA says monomer -- Annotation transfered from 1i4p 1se3 NO 1 1 NPS NPS 7552730 7552730 SEB is monomeric 1se4 NO 1 1 NPS NPS 7552730 7552730 SEB is monomeric -- Annotation transfered from 1se3 1se8 YES 2 2 C2 C2 15159541 15159541 interesting - this is dimeric in a thermophile while it is tetrameric in most other organisms! 1sef YES 1 8 NPS D4 0 0 Interface geometry conserved with 1sq4 (30%) 1seg PROBNOT 1 1 NPS NPS 15133045 15133045 Paper says nothing - PISA says monomer 1sei NO 2 2 C2 C2 8805594 8805594 Interface geometry conserved with 1an7 (58%) 1sek PROBYES 2 1 C2 NPS 10368276 10368276 Paper says nothing, family mostly monomeric and PISA says monomer 1sel_1 NO 1 1 NPS NPS 8512925 9789015 - automatic transfer from 1be6 1sel_2 NO 1 1 NPS NPS 8512925 9789015 - automatic transfer from 1be6 1sem PROBYES 2 1 C2 NPS 7802869 7802869 PISA says monomer and related proteins are monomeric 1sen PROBNOT 1 1 NPS NPS 0 0 No paper, PISA says monomer 1sep NO 2 2 C2 C2 9405351 9405351 paper says dimer -- Annotation transfered from 1oaa 1sez YES 2 2 C2 C2 15057273 15057273 Paper says dimer -- Paper indicates another dimeric than the one reconstructed here 1sf2 NO 4 4 D2 D2 15323550 0 tetramer formation, the dimer-dimer interaction in E. coli GABA-AT is weak. This was confirmed by gel filtration experiments, in which it was shown that a fraction of the enzyme exists as dimers (data not shown). Increasing the PLP concentration promotes tetramer formation. - interessting -- Annotation transfered from 1sff 1sf3 NO 1 1 NPS NPS 15260480 15260480 Amicyanin is a monomeric protein with a molecular weight of 15000 (Husain & Davidson, 1985) -- Annotation transfered from 1aaj 1sf5 NO 1 1 NPS NPS 15260480 15260480 Amicyanin is a monomeric protein with a molecular weight of 15000 (Husain & Davidson, 1985) -- Annotation transfered from 1aaj 1sfd_1 NO 1 1 NPS NPS 15260480 8495197 Amicyanin is a monomeric protein with a molecular weight of 15000 (Husain & Davidson, 1985) - automatic transfer from 1aaj 1sfd_2 NO 1 1 NPS NPS 15260480 8495197 Amicyanin is a monomeric protein with a molecular weight of 15000 (Husain & Davidson, 1985) - automatic transfer from 1aaj 1sff NO 4 4 D2 D2 15323550 15323550 tetramer formation, the dimer-dimer interaction in E. coli GABA-AT is weak. This was confirmed by gel filtration experiments, in which it was shown that a fraction of the enzyme exists as dimers (data not shown). Increasing the PLP concentration promotes tetramer formation. - interessting 1sfh_1 NO 1 1 NPS NPS 15260480 8495197 Amicyanin is a monomeric protein with a molecular weight of 15000 (Husain & Davidson, 1985) - automatic transfer from 1aaj 1sfh_2 NO 1 1 NPS NPS 15260480 8495197 Amicyanin is a monomeric protein with a molecular weight of 15000 (Husain & Davidson, 1985) - automatic transfer from 1aaj 1sfi PROBNOT 1 1 NPS NPS 10390350 10390350 -- Annotation transfered from 1az8 1sfn NO 2 2 C2 C2 0 0 Interface geometry conserved with 1sef (32%) 1sfy_1 NO 2 2 C2 C2 15281133 9545381 - automatic transfer from 1ax0 1sfy_2 NO 2 2 C2 C2 15281133 9545381 - automatic transfer from 1ax0 1sfy_3 NO 2 2 C2 C2 15281133 9545381 - automatic transfer from 1ax0 1sfy_4 NO 2 2 C2 C2 15281133 9545381 - automatic transfer from 1ax0 1sg0 NO 2 2 C2 C2 15350128 10433694 - automatic transfer from 1qr2 1sg3 NO 6 6 D3 D3 15020593 15020593 Paper says hexamer 1sg6_1 PROBYES 1 2 NPS C2 15103156 12614613 BU changed since last release and is now incorrect - Paper says dimer - Interface geometry conserved with 1ujn (38%) - automaticaly inferred from 1nvd 1sg6_2 PROBYES 1 2 NPS C2 15103156 12614613 BU changed since last release and is now incorrect - Paper says dimer - Interface geometry conserved with 1ujn (38%) - automaticaly inferred from 1nvd 1sg9_1 PROBYES 2 1 C2 NPS 0 12741815 BU changed since last release and is now incorrect - PrmC eluted at a volume consistent with a monomeric state. - automaticaly inferred from 1nv9 1sg9_2 PROBYES 2 1 C2 NPS 0 12741815 BU changed since last release and is now incorrect - PrmC eluted at a volume consistent with a monomeric state. - automaticaly inferred from 1nv9 1sgt PROBNOT 1 1 NPS NPS 3135412 3135412 Paper says nothing, related structures are monomeric and PISA says monomer -- Annotation transfered from 1os8 1sgw PROBNOT 1 1 NPS NPS 0 0 No paper, ABC transp dimerize upon nucleotide and there is none here. 1sgx_1 PROBNOT 1 1 NPS NPS 15084592 11980702 BU changed since last release and is now corrected - Paper says: the protein is a monomer in solution - automaticaly inferred from 1l9m 1sgx_2 PROBNOT 1 1 NPS NPS 15084592 11980702 BU changed since last release and is now corrected - Paper says: the protein is a monomer in solution - automaticaly inferred from 1l9m 1sh5 PROBYES 2 1 C2 NPS 15128297 15128297 Assumed in paper 1sh6 PROBNOT 1 1 NPS NPS 15128297 15128297 1sha NO 1 1 NPS NPS 1379696 1379696 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1shb NO 1 1 NPS NPS 1379696 1379696 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1shd NO 1 1 NPS NPS 7527393 7527393 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1shf NA 4 2 C2 C2 7687536 7687536 The flow rate was 1 ml/min. SH3 eluted in two peaks, centred at 85 and 105 ml, indicating a possible dimer-monomer equilibrium. 1shg PROBNOT 1 1 NPS NPS 1279434 1279434 -- Annotation transfered from 1neg 1shk_1 PROBNOT 1 1 NPS NPS 15299895 11369852 BU changed since last release and is now corrected - Paper says: This monomeric enzyme shows 53% amino-acid identity to E. coli SK II and, at less than 19 kD, is one of the smallest kinases so far described. - automatic transfer from 1e6c_2 1shk_2 PROBNOT 1 1 NPS NPS 15299895 11369852 BU changed since last release and is now corrected - Paper says: This monomeric enzyme shows 53% amino-acid identity to E. coli SK II and, at less than 19 kD, is one of the smallest kinases so far described. - automatic transfer from 1e6c_2 1shv PROBNOT 1 1 NPS NPS 10231522 10231522 -- Annotation transfered from 1ong 1si7 PROBNOT 1 1 NPS NPS 14999002 15208439 BU changed since last release and is now corrected - Oligomer not mentioned - automaticaly inferred from 1sb7 1si8 NO 4 4 D2 D2 15272159 0 Interface geometry conserved with 1mqf (50% id) 1sif PROBNOT 1 1 NPS NPS 15122885 15122885 Ubiquitin binds to proteins in different forms that may lead to the degradation of the target protein. For this reason I will consider all the ubiquitin structures to be correct. i.e. different forms may exist. -- Annotation transfered from 1ubq 1sih NO 2 2 C2 C2 15323556 15323556 Interface geometry conserved with 1ksi (25%) -- Annotation transfered from 1sii 1sii NO 2 2 C2 C2 15323556 15323556 Interface geometry conserved with 1ksi (25%) 1sip NO 2 2 C2 C2 8196050 8196050 -- Annotation transfered from 1az5 1siv NO 2 2 C2 C2 8241159 8241159 1six NO 3 3 C3 C3 15276840 15276840 Paper says: dUTPases are primarily homotrimeric and catalyze the metal ion dependent hydrolysis of dUTP to 2′-deoxyuridine 5′-monophosphate (dUMP) and pyrophosphate. -- Annotation transfered from 1snf 1siz PROBNOT 2 2 C2 C2 15122884 15122884 Pyrococcus furiosus ferredoxin is subject to a monomer/dimer equilibrium as a function of ionic strength. At physiological ionic strength, approximately 0.35 M NaCl, the protein is very predominantly homodimer. -- Annotation transfered from 1sj1 1sj0 NO 2 2 C2 C2 15084115 15084115 paper says dimer -- Annotation transfered from 1err 1sj1 PROBNOT 2 2 C2 C2 15122884 12417337 Pyrococcus furiosus ferredoxin is subject to a monomer/dimer equilibrium as a function of ionic strength. At physiological ionic strength, approximately 0.35 M NaCl, the protein is very predominantly homodimer. 1sja NO 8 8 D4 D4 15134446 15134446 Paper says octamer 1sjb NO 8 8 D4 D4 15134446 15134446 Paper says octamer -- Annotation transfered from 1sja 1sjc NO 8 8 D4 D4 15134446 15134446 Paper says octamer -- Annotation transfered from 1sja 1sjd NO 8 8 D4 D4 15134446 15134446 Paper says octamer -- Annotation transfered from 1sja 1sjm NO 3 3 C3 C3 15131305 0 -- Annotation transfered from 1as7 1sjn NO 3 3 C3 C3 15276840 15276840 Paper says: dUTPases are primarily homotrimeric and catalyze the metal ion dependent hydrolysis of dUTP to 2′-deoxyuridine 5′-monophosphate (dUMP) and pyrophosphate. -- Annotation transfered from 1snf 1sjv YES 1 2 NPS C2 15094039 15094039 Domain swapped dimer - also observed with MS 1sjw NO 4 4 D2 D2 15071504 15071504 Paper says: Gel filtration chromatography experiments however also suggest that SnoaL forms a tetramer in solution (data not shown), consistent with the quaternary structure revealed by the crystallographic analysis. 1sjy NO 2 2 C2 C2 15123424 15123424 Paper says dimer -- Annotation transfered from 1sz3 1skf PROBNOT 1 1 NPS NPS 10419503 10419503 -- Annotation transfered from 1es2 1skg PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 1tgm 1skj NO 1 1 NPS NPS 9371236 9371236 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution -- Annotation transfered from 1o45 1sku NO 12 12 D3 D3 15014067 15014067 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1sl3 PROBNOT 1 1 NPS NPS 15163182 15163182 -- Annotation transfered from 1doj 1sl4 NA 1 1 NPS NPS 15195147 15195147 Seems that it is not really a monomer, but it is not really a dimer either - Paper says: The DC-SIGN crystals contain pairs of CRDs cross-linked by the oligosaccharide, in which one monomer forms the same contacts with the oligosaccharide observed for DC-SIGNR, while the partner monomer interacts with the terminal N-acetylglucosamine (GlcNAc) on the alpha 1-3 branch 1sl5 NA 1 1 NPS NPS 15195147 15195147 Seems that it is not really a monomer, but it is not really a dimer either - Paper says: The DC-SIGN crystals contain pairs of CRDs cross-linked by the oligosaccharide, in which one monomer forms the same contacts with the oligosaccharide observed for DC-SIGNR, while the partner monomer interacts with the terminal N-acetylglucosamine (GlcNAc) on the alpha 1-3 branch -- Annotation transfered from 1sl4 1sl6_1 NA 1 2 NPS C2 15195147 11739956 BU changed since last release and is now incorrect - I dont get if it is a dimer or not? - In the DC-SIGN crystals, GlcNAc1 also forms a typical C-type lectin Ca2+ coordination and hydrogen bond network at the principal Ca2+ site on the partner monomer in the dimer, thereby cross-linking the two monomers - automaticaly inferred from 1k9j 1sl6_2 NA 1 2 NPS C2 15195147 11739956 BU changed since last release and is now incorrect - I dont get if it is a dimer or not? - In the DC-SIGN crystals, GlcNAc1 also forms a typical C-type lectin Ca2+ coordination and hydrogen bond network at the principal Ca2+ site on the partner monomer in the dimer, thereby cross-linking the two monomers - automaticaly inferred from 1k9j 1sl6_3 NA 1 2 NPS C2 15195147 11739956 BU changed since last release and is now incorrect - I dont get if it is a dimer or not? - In the DC-SIGN crystals, GlcNAc1 also forms a typical C-type lectin Ca2+ coordination and hydrogen bond network at the principal Ca2+ site on the partner monomer in the dimer, thereby cross-linking the two monomers - automaticaly inferred from 1k9j 1sl6_4 NA 1 2 NPS C2 15195147 11739956 BU changed since last release and is now incorrect - I dont get if it is a dimer or not? - In the DC-SIGN crystals, GlcNAc1 also forms a typical C-type lectin Ca2+ coordination and hydrogen bond network at the principal Ca2+ site on the partner monomer in the dimer, thereby cross-linking the two monomers - automaticaly inferred from 1k9j 1sl6_5 NA 1 2 NPS C2 15195147 11739956 BU changed since last release and is now incorrect - I dont get if it is a dimer or not? - In the DC-SIGN crystals, GlcNAc1 also forms a typical C-type lectin Ca2+ coordination and hydrogen bond network at the principal Ca2+ site on the partner monomer in the dimer, thereby cross-linking the two monomers - automaticaly inferred from 1k9j 1sl6_6 NA 1 2 NPS C2 15195147 11739956 BU changed since last release and is now incorrect - I dont get if it is a dimer or not? - In the DC-SIGN crystals, GlcNAc1 also forms a typical C-type lectin Ca2+ coordination and hydrogen bond network at the principal Ca2+ site on the partner monomer in the dimer, thereby cross-linking the two monomers - automaticaly inferred from 1k9j 1sl7 PROBNOT 1 1 NPS NPS 15689515 12755603 Paper does not mention a dimer - PISA says monomer - automatic transfer from 1jf2 1sl9 PROBNOT 1 1 NPS NPS 0 12755603 Paper does not mention a dimer - PISA says monomer - automatic transfer from 1jf2 1sla NO 2 2 C2 C2 7773775 7773775 Paper says dimer -- Annotation transfered from 1slt 1slb_1 NO 2 2 C2 C2 7773775 8108426 Paper says dimer - automatic transfer from 1slt 1slb_2 NO 2 2 C2 C2 7773775 8108426 Paper says dimer - automatic transfer from 1slt 1slc_1 NO 2 2 C2 C2 7773775 8108426 Paper says dimer - automatic transfer from 1slt 1slc_2 NO 2 2 C2 C2 7773775 8108426 Paper says dimer - automatic transfer from 1slt 1sld NO 4 4 D2 D2 7492542 7492542 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1sle NO 4 4 D2 D2 7492542 7492542 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1slf NO 4 4 D2 D2 7492542 7492542 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1slg NO 4 4 D2 D2 7492542 7492542 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1slh NO 3 3 C3 C3 15276840 15276840 Paper says: dUTPases are primarily homotrimeric and catalyze the metal ion dependent hydrolysis of dUTP to 2′-deoxyuridine 5′-monophosphate (dUMP) and pyrophosphate. -- Annotation transfered from 1snf 1sln PROBNOT 1 1 NPS NPS 8535233 8535233 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme -- Annotation transfered from 1caq 1slt NO 2 2 C2 C2 8108426 8108426 Paper says dimer 1sm8 NO 3 3 C3 C3 15276840 15276840 Paper says: dUTPases are primarily homotrimeric and catalyze the metal ion dependent hydrolysis of dUTP to 2′-deoxyuridine 5′-monophosphate (dUMP) and pyrophosphate. -- Annotation transfered from 1snf 1sm9_1 NO 2 2 C2 C2 15320875 12102621 Forms a dimer, paper interesting regarding the evolution of oligomeric state - good candidate - automatic transfer from 1jez 1sm9_2 NO 2 2 C2 C2 15320875 12102621 Forms a dimer, paper interesting regarding the evolution of oligomeric state - good candidate - automatic transfer from 1jez 1smc NO 3 3 C3 C3 15276840 15276840 Paper says: dUTPases are primarily homotrimeric and catalyze the metal ion dependent hydrolysis of dUTP to 2′-deoxyuridine 5′-monophosphate (dUMP) and pyrophosphate. -- Annotation transfered from 1snf 1smf PROBNOT 1 1 NPS NPS 7798176 7798176 -- Annotation transfered from 1az8 1smh NO 1 1 NPS NPS 15196017 15196017 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1smi_1 NA 1 1 NPS NPS 15020590 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1smi_2 NA 1 1 NPS NPS 15020590 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1smj_1 NA 1 1 NPS NPS 15020590 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1smj_2 NA 1 1 NPS NPS 15020590 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1smj_3 NA 1 1 NPS NPS 15020590 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1smj_4 NA 1 1 NPS NPS 15020590 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1sml YES 1 4 NPS D2 9811546 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. 1smm PROBNOT 1 1 NPS NPS 15067525 15067525 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1fhm 1smo PROBYES 2 1 NS NPS 15351648 15351648 Paper says: Hence, when taken together, the biophysical and crystallographic evidence presented here, strongly suggest that in solution the globular head of the TREM-1 ectodomain is monomeric. 1smu PROBNOT 1 1 NPS NPS 15067525 15067525 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1fhm 1smw PROBNOT 1 1 NPS NPS 15067525 15067525 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 1fhm 1sn0 NO 4 4 D2 D2 15082720 15082720 Paper says tetramer 1sn1 PROBNOT 1 1 NPS NPS 10493862 10493862 Paper mentions that BMK M1 are monomeric -- Annotation transfered from 1t7b 1sn2 NO 4 4 D2 D2 15082720 15082720 Paper says tetramer -- Annotation transfered from 1sn0 1sn4 PROBNOT 1 1 NPS NPS 10493862 10493862 Paper says nothing - PISA says monomer and related proteins are monomeric 1sn5 NO 4 4 D2 D2 15082720 15082720 Paper says tetramer -- Annotation transfered from 1sn0 1snb PROBNOT 1 1 NPS NPS 8780783 8780783 Paper says nothing, PISA says monomer and related proteins are monomeric 1snc NO 1 1 NPS NPS 2780539 2780539 Paper says monomeric -- Annotation transfered from 1ena 1snd YES 4 2 C2 C2 7552745 7552745 Domain swapped dimer 1snf NO 3 3 C3 C3 15276840 15276840 Paper says: dUTPases are primarily homotrimeric and catalyze the metal ion dependent hydrolysis of dUTP to 2′-deoxyuridine 5′-monophosphate (dUMP) and pyrophosphate. 1snk NO 1 1 NPS NPS 15177446 15177446 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa -- Annotation transfered from 1atk 1snm NO 1 1 NPS NPS 2397218 2397218 Paper says monomeric -- Annotation transfered from 1ena 1sno NO 1 1 NPS NPS 8880915 8880915 Paper says monomeric -- Annotation transfered from 1ena 1snp NO 1 1 NPS NPS 8880915 8880915 Paper says monomeric -- Annotation transfered from 1ena 1snq NO 1 1 NPS NPS 8880915 8880915 Paper says monomeric -- Annotation transfered from 1ena 1snr NO 3 3 C3 C3 15131298 15131298 -- Annotation transfered from 1as7 1so3 NO 2 2 C2 C2 15157078 15157078 Interface geometry conserved with 1lor -- Annotation transfered from 1q6q 1so4 NO 2 2 C2 C2 15157078 15157078 Interface geometry conserved with 1lor -- Annotation transfered from 1q6q 1so5 NO 2 2 C2 C2 15157078 15157078 Interface geometry conserved with 1lor -- Annotation transfered from 1q6q 1so6 NO 2 2 C2 C2 15157078 15157078 Interface geometry conserved with 1lor -- Annotation transfered from 1q6q 1so8 NA 4 4 NS D2 15087549 15087549 I think it should be 4 subs, D2 sym, but PISA says D4 with 8 subs. A close rat homolog (>80%) has four subunits. Could be interesting to dig 1soa NO 2 2 C2 C2 15181200 15181200 -- Annotation transfered from 1ucf 1sog PROBNOT 1 1 NPS NPS 15236591 0 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1soi NO 2 2 C2 C2 15123424 15123424 Paper says dimer -- Annotation transfered from 1sz3 1sok NO 4 4 D2 D2 15210129 15210129 transthyretin is tetrameric -- Annotation transfered from 1fh2 1som PROBNOT 2 2 NS NS 10353814 10353814 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. 1soq_1 PROBNOT 4 4 D2 D2 15210129 9789022 BU changed since last release and is now corrected - All dimers similar to that one are found to be tetramers by PISA. Because the native structure is tetrameric, dimer are certainly mistakes - automaticaly inferred from 1bmz 1soq_2 PROBNOT 4 4 D2 D2 15210129 9789022 BU changed since last release and is now corrected - All dimers similar to that one are found to be tetramers by PISA. Because the native structure is tetrameric, dimer are certainly mistakes - automaticaly inferred from 1bmz 1sos_1 PROBNOT 2 2 C2 C2 1463506 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1sos_2 PROBNOT 2 2 C2 C2 1463506 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1sos_3 PROBNOT 2 2 C2 C2 1463506 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1sos_4 PROBNOT 2 2 C2 C2 1463506 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1sos_5 PROBNOT 2 2 C2 C2 1463506 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1sot NO 3 3 C3 C3 15137941 15137941 Interface geometry conserved with 1lcy (31%) 1soz NO 3 3 C3 C3 15137941 15137941 Interface geometry conserved with 1lcy (31%) -- Annotation transfered from 1sot 1sp5 NO 2 2 C2 C2 0 9083478 - automatic transfer from 1ajx 1spa NO 2 2 C2 C2 1610831 1610831 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 1spd NO 2 2 C2 C2 8351519 8351519 Mammalian Cu,Zn SOD assembles into an unusually stable homodimer with exquisite substrate specificity. Interface conserved down to 50% (at least with 1jcv) -- Annotation transfered from 1n19 1spe NO 1 1 NPS NPS 8642596 8642596 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1sph PROBYES 2 1 C2 NPS 7704530 9334229 E. coli HPr is a small, monomeric protein (I assume it is similar for subtilis) + Inspection of the crystal structure clearly shows very loose packing - PISA has problems with this entry. 1spi NO 4 4 D2 D2 7703243 7703243 1spq NO 2 2 C2 C2 15166315 15166315 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1sq7 1spr_1 PROBNOT 1 1 NPS NPS 7680960 6254988 BU changed since last release and is now corrected - In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution - automaticaly inferred from 1a07 1spr_2 PROBNOT 1 1 NPS NPS 7680960 6254988 BU changed since last release and is now corrected - In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution - automaticaly inferred from 1a07 1spr_3 PROBNOT 1 1 NPS NPS 7680960 6254988 BU changed since last release and is now corrected - In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution - automaticaly inferred from 1a07 1spr_4 PROBNOT 1 1 NPS NPS 7680960 6254988 BU changed since last release and is now corrected - In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution - automaticaly inferred from 1a07 1sps YES 3 1 NS NPS 7680960 6254988 In addition, it is clear that the enzymatically active pp60 behaves largely as a monomer in solution 1spx NO 4 4 D2 D2 0 0 PISA says tetramer and I believe it 1sq4 NO 8 8 D4 D4 0 0 Interface geometry conserved with 1sef (30%) 1sq6 YES 1 6 NPS D3 16131758 0 Identical/homologs are true hexamers and PISA says hexamer 1sq7 NO 2 2 C2 C2 15166315 15166315 Interface geometry conserved with 1m6j (52%) - paper says dimer 1sqa PROBNOT 1 1 NPS NPS 15149645 15149645 -- Annotation transfered from 1owd 1sqc PROBNOT 1 1 NPS NPS 9295270 9295270 Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer 1sqd PROBNOT 2 2 C2 C2 15301540 15301540 Interface geometry conserved with 1sqi (34%) -- Annotation transfered from 1tfz 1sqe NO 2 2 C2 C2 15520015 15520015 Interface geometry conserved with 1iuj (33%) 1sqi PROBNOT 2 2 C2 C2 15301540 15301540 Interface geometry conserved with 1tfz (34%) 1sqn_1 PROBYES 1 2 NPS C2 15189034 15189034 BU changed since last release and is now incorrect - no info in paper, PISA says dimer - automaticaly inferred from 1sr7 1sqn_2 PROBYES 1 2 NPS C2 15189034 15189034 BU changed since last release and is now incorrect - no info in paper, PISA says dimer - automaticaly inferred from 1sr7 1sqo PROBNOT 1 1 NPS NPS 15149645 15149645 -- Annotation transfered from 1owd 1sqt PROBNOT 1 1 NPS NPS 15149645 15149645 -- Annotation transfered from 1owd 1sqz PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 1tgm 1sr0 NO 1 1 NPS NPS 0 0 Elutes as a monomer - Papers says: The second peak in this final chromatographic step corresponded to a molecular mass of 40 kDa. -- Annotation transfered from 1ljy 1sr5 NA 3 3 NPS NA 15311268 15311268 BU changed since last release and is now incorrect - Email sent 1sr7 PROBNOT 2 2 C2 C2 15189034 15189034 no info in paper, PISA says dimer 1srd YES 4 2 NS C2 1880134 1880134 SOD is a dimer 1sre NO 4 4 D2 D2 -1 0 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1srf NO 4 4 D2 D2 -1 0 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1srg NO 4 4 D2 D2 -1 0 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1srh NO 4 4 D2 D2 -1 0 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1sri NO 4 4 D2 D2 -1 0 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1srj NO 4 4 D2 D2 -1 0 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1srn NO 1 1 NPS NPS 3680234 3680234 -- Annotation transfered from 6rsa 1srr_1 PROBYES 2 1 C2 NPS 8805550 15255896 BU changed since last release and is now incorrect - Spo0F is a monomer in both unphosphorylated and phosphorylated forms. - automaticaly inferred from 1nat 1srr_2 PROBYES 2 1 C2 NPS 8805550 15255896 BU changed since last release and is now incorrect - Spo0F is a monomer in both unphosphorylated and phosphorylated forms. - automaticaly inferred from 1nat 1sru NO 4 4 D2 D2 15169953 15169953 Structure shown in paper -- Annotation transfered from 1qvc 1srx PROBNOT 1 1 NPS NPS 1094461 1094461 SP says monomer -- Annotation transfered from 1tho 1ss9 PROBNOT 1 1 NPS NPS 15075344 15075344 Paper says: The structure of LgtC is a monomer comprising 286 residues organized into two domains. - No direct evidence provided - PISA says monomer too. -- Annotation transfered from 1g9r 1ssd NO 2 2 C2 C2 15166315 15166315 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1sq7 1ssg NO 2 2 C2 C2 15166315 15166315 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1sq7 1ssh PROBNOT 1 1 NPS NPS 0 0 No paper, related structures are monomers and PISA says monomer - automatic transfer from 1oot 1ssm NO 6 6 D3 D3 15147185 15147185 Paper says: The quaternary structure of all known hexapeptide acyltransferases is trimeric with the exception of SAT, which had been predicted to adopt a hexameric structure, based on equilibrium sedimentation studies and the appearance of electron micrographs of negatively stained particles -- Annotation transfered from 1sst 1ssq NO 6 6 D3 D3 15147185 15147185 Paper says: The quaternary structure of all known hexapeptide acyltransferases is trimeric with the exception of SAT, which had been predicted to adopt a hexameric structure, based on equilibrium sedimentation studies and the appearance of electron micrographs of negatively stained particles -- Annotation transfered from 1sst 1sst NO 6 6 D3 D3 15147185 15147185 Paper says: The quaternary structure of all known hexapeptide acyltransferases is trimeric with the exception of SAT, which had been predicted to adopt a hexameric structure, based on equilibrium sedimentation studies and the appearance of electron micrographs of negatively stained particles 1ssx NO 1 1 NPS NPS 15111063 15111063 9846867 says monomer -- Annotation transfered from 1p05 1ssy_1 PROBNOT 1 1 NPS NPS 15340171 8503008 BU changed since last release and is now corrected - Phage T4 Lysosyme is monomeric - automaticaly inferred from 137l 1ssy_2 PROBNOT 1 1 NPS NPS 15340171 8503008 BU changed since last release and is now corrected - Phage T4 Lysosyme is monomeric - automaticaly inferred from 137l 1st2 NO 1 1 NPS NPS 3286644 3286644 -- Annotation transfered from 1yja 1st3 NO 1 1 NPS NPS 1453465 1453465 -- Annotation transfered from 1c9n 1sta NO 1 1 NPS NPS 8019410 8019410 Paper says monomeric -- Annotation transfered from 1ena 1stb NO 1 1 NPS NPS 8019410 8019410 Paper says monomeric -- Annotation transfered from 1ena 1stc NO 1 1 NPS NPS 9438863 9438863 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1ste PROBNOT 1 1 NPS NPS 7582894 7582894 dimer not mentioned in literature, PISA says monomer -- Annotation transfered from 1i4p 1stg NO 1 1 NPS NPS 7703245 7703245 Paper says monomeric -- Annotation transfered from 1ena 1sth NO 1 1 NPS NPS 7703245 7703245 Paper says monomeric -- Annotation transfered from 1ena 1stn NO 1 1 NPS NPS 1896431 1896431 Paper says monomeric -- Annotation transfered from 1ena 1stp NO 4 4 D2 D2 2911722 2911722 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1stq PROBNOT 1 1 NPS NPS 15236591 0 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 1str NO 4 4 D2 D2 8537386 8537386 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1sts NO 4 4 D2 D2 8537386 8537386 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1sty NO 1 1 NPS NPS 8475069 8475069 Paper says monomeric -- Annotation transfered from 1ena 1stz YES 3 2 NS C2 15979091 15979091 The Tm_HrcA protein crystallizes as a dimer. 1su2 NO 2 2 C2 C2 15123424 15123424 Paper says dimer -- Annotation transfered from 1sz3 1su4 NO 1 1 NPS NPS 10864310 10864310 -- Annotation transfered from 1kju 1su5 NO 2 2 C2 C2 15166315 15166315 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1sq7 1sua NO 1 1 NPS NPS 9552156 9552156 -- Annotation transfered from 1yja 1sub NO 1 1 NPS NPS 8332608 8332608 -- Annotation transfered from 1yja 1suc NO 1 1 NPS NPS 8332608 8332608 -- Annotation transfered from 1yja 1sud NO 1 1 NPS NPS 8332608 8332608 -- Annotation transfered from 1yja 1sue NO 1 1 NPS NPS -1 0 -- Annotation transfered from 1yja 1sug PROBNOT 1 1 NPS NPS 15333922 15333922 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1suo NO 1 1 NPS NPS 15100217 15100217 Paper says monomer dimer equilibrium -- Annotation transfered from 1po5 1sup NO 1 1 NPS NPS 15299573 0 -- Annotation transfered from 1yja 1sux NO 2 2 C2 C2 15321726 0 Interface geometry conserved with 1m6j (45%) - paper says dimer -- Annotation transfered from 1ci1 1sv3 PROBNOT 1 1 NPS NPS 16596639 16596639 SP says monomer -- Annotation transfered from 1tgm 1sv9 PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 1tgm 1svb YES 1 2 NPS C2 7753193 7753193 Interface geometry conserved with 1oan (38%) 1sve NO 1 1 NPS NPS 14998327 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 1svg NO 1 1 NPS NPS 14998327 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 1svh NO 1 1 NPS NPS 14998327 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 1svk NO 1 1 NPS NPS 15128951 15128951 Hetero-trimer with a 1:1:1 stoichiometry -- Annotation transfered from 1svs 1svn NO 1 1 NPS NPS 1738156 1738156 -- Annotation transfered from 1c9n 1svp NA 2 2 NS NS 8736552 8736552 Unclear, email sent 1svs NO 1 1 NPS NPS 15128951 15128951 Hetero-trimer with a 1:1:1 stoichiometry 1sw0 NO 2 2 C2 C2 15166315 15166315 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1sq7 1sw3 NO 2 2 C2 C2 15166315 15166315 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1sq7 1sw6 YES 2 1 NS NPS 10048928 10048928 9719633: Furthermore, the random distribution of residuals indicates that both proteins are monodisperse monomers in solution. 1sw7 NO 2 2 C2 C2 15166315 15166315 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1sq7 1swa NO 4 4 D2 D2 9194176 9194176 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swb NO 4 4 D2 D2 9194176 9194176 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swc NO 4 4 D2 D2 9194176 9194176 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swd NO 4 4 D2 D2 9194176 9194176 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swe NO 4 4 D2 D2 9194176 9194176 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swf NO 4 4 D2 D2 9568892 9568892 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swg NO 4 4 D2 D2 9568892 9568892 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swh NO 4 4 D2 D2 9636711 9636711 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swi NO 3 3 C3 C3 8646536 8646536 Paper says trimer - Engineered Leucine Zipper protein GCN4 -- Annotation transfered from 1zij 1swj NO 4 4 D2 D2 9636711 9636711 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swk NO 4 4 D2 D2 9636711 9636711 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swl NO 4 4 D2 D2 9636711 9636711 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swm NO 1 1 NPS NPS 1994031 1994031 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1swn NO 4 4 D2 D2 9636711 9636711 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swo NO 4 4 D2 D2 9636711 9636711 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swp NO 4 4 D2 D2 9636711 9636711 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swq NO 4 4 D2 D2 9636711 9636711 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swr NO 4 4 D2 D2 9636711 9636711 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1sws NO 4 4 D2 D2 10411884 10411884 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swt NO 4 4 D2 D2 10411884 10411884 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swu NO 4 4 D2 D2 10329773 10329773 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1swy NO 1 1 NPS NPS 15388918 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1sx2 NO 1 1 NPS NPS 15388918 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1sx7 NO 1 1 NPS NPS 15388918 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1sxk PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 1tgm 1sxn NO 2 2 C2 C2 -1 0 PAper, SP say dimer -- Annotation transfered from 1cob 1sxp_1 PROBNOT 1 1 NPS NPS 15178685 8062817 SP says monomer - automatic transfer from 1bgt 1sxp_2 PROBNOT 1 1 NPS NPS 15178685 8062817 SP says monomer - automatic transfer from 1bgt 1sxq_1 PROBNOT 1 1 NPS NPS 15178685 8062817 SP says monomer - automatic transfer from 1bgt 1sxq_2 PROBNOT 1 1 NPS NPS 15178685 8062817 SP says monomer - automatic transfer from 1bgt 1sxs NO 2 2 C2 C2 -1 0 PAper, SP say dimer -- Annotation transfered from 1cob 1sxz NO 2 2 C2 C2 -1 0 PAper, SP say dimer -- Annotation transfered from 1cob 1syb NO 1 1 NPS NPS 2716830 2716830 Paper says monomeric -- Annotation transfered from 1ena 1syc NO 1 1 NPS NPS 8172877 8172877 Paper says monomeric -- Annotation transfered from 1ena 1syd NO 1 1 NPS NPS 8172877 8172877 Paper says monomeric -- Annotation transfered from 1ena 1sye NO 1 1 NPS NPS 8172877 8172877 Paper says monomeric -- Annotation transfered from 1ena 1syf NO 1 1 NPS NPS 8172877 8172877 Paper says monomeric -- Annotation transfered from 1ena 1syg NO 1 1 NPS NPS 8172877 8172877 Paper says monomeric -- Annotation transfered from 1ena 1syh PROBNOT 2 2 C2 C2 15591246 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1syi PROBNOT 2 2 C2 C2 15591246 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1syn NO 2 2 C2 C2 8805515 0 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1syt NO 1 1 NPS NPS 0 0 Elutes as a monomer - Papers says: The second peak in this final chromatographic step corresponded to a molecular mass of 40 kDa. -- Annotation transfered from 1ljy 1sz3 NO 2 2 C2 C2 15123424 15123424 Paper says dimer 1sz8 PROBNOT 1 1 NPS NPS 0 0 Paper says nothing about oligomer - PISA says monomer -- Annotation transfered from 1td7 1szc PROBNOT 1 1 NPS NPS 15150415 14604530 acetyl-lysine peptide binding induces a trimer-monomer protein transition involving nonconserved Sir2 residues - interesting 1szd PROBNOT 1 1 NPS NPS 15150415 0 acetyl-lysine peptide binding induces a trimer-monomer protein transition involving nonconserved Sir2 residues - interesting -- Annotation transfered from 1szc 1sze NO 4 4 C4 C4 15260495 11914072 Paper says tetramer. Note that one domain has been artificially truncated. -- Annotation transfered from 1kbj 1szf NO 4 4 C4 C4 15260495 11914072 Paper says tetramer. Note that one domain has been artificially truncated. -- Annotation transfered from 1kbj 1szg NO 4 4 C4 C4 15260495 11914072 Paper says tetramer. Note that one domain has been artificially truncated. -- Annotation transfered from 1kbj 1szj NO 4 4 D2 D2 6655693 6655693 SP says homotetramer - papers too 1szk NO 4 4 D2 D2 15723541 15323550 tetramer formation, the dimer-dimer interaction in E. coli GABA-AT is weak. This was confirmed by gel filtration experiments, in which it was shown that a fraction of the enzyme exists as dimers (data not shown). Increasing the PLP concentration promotes tetramer formation. - interessting - automatic transfer from 1sff 1szm_1 NA 1 1 NPS NPS 14996846 8251932 BU changed since last release and is now corrected - Paper does not mention an oligomer - automaticaly inferred from 1cmk 1szm_2 NA 1 1 NPS NPS 14996846 8251932 BU changed since last release and is now corrected - Paper does not mention an oligomer - automaticaly inferred from 1cmk 1szn PROBNOT 1 1 NPS NPS 15136043 15136043 Paper says nothing - PISA says monomer 1szo_1 PROBYES 3 6 C3 D3 15138275 12421807 BU changed since last release and is now incorrect - - automaticaly inferred from 1o8u 1szo_2 PROBYES 3 6 C3 D3 15138275 12421807 BU changed since last release and is now incorrect - - automaticaly inferred from 1o8u 1szo_3 PROBYES 3 6 C3 D3 15138275 12421807 BU changed since last release and is now incorrect - - automaticaly inferred from 1o8u 1szo_4 PROBYES 3 6 C3 D3 15138275 12421807 BU changed since last release and is now incorrect - - automaticaly inferred from 1o8u 1szp_1 PROBYES 6 10 NS NS 15235592 15235592 BU changed since last release and is now incorrect - Paper says filament 1szp_2 PROBYES 6 10 NS NS 15235592 15235592 BU changed since last release and is now incorrect - Paper says filament - automatic transfer from 1szp_1 1szp_3 PROBYES 6 10 NS NS 15235592 15235592 BU changed since last release and is now incorrect - Paper says filament - automatic transfer from 1szp_1 1szs NO 4 4 D2 D2 15723541 15323550 tetramer formation, the dimer-dimer interaction in E. coli GABA-AT is weak. This was confirmed by gel filtration experiments, in which it was shown that a fraction of the enzyme exists as dimers (data not shown). Increasing the PLP concentration promotes tetramer formation. - interessting - automatic transfer from 1sff 1szu NO 4 4 D2 D2 15723541 15323550 tetramer formation, the dimer-dimer interaction in E. coli GABA-AT is weak. This was confirmed by gel filtration experiments, in which it was shown that a fraction of the enzyme exists as dimers (data not shown). Increasing the PLP concentration promotes tetramer formation. - interessting - automatic transfer from 1sff 1szx NO 4 4 D2 D2 15170341 15170341 Paper says tetramer -- Annotation transfered from 1n0j 1t02 PROBNOT 2 2 C2 C2 12621048 0 Paper says dimer although no hard evidence is given. -- Annotation transfered from 1qax 1t0i PROBNOT 2 2 C2 C2 15184374 15184374 1t0o PROBNOT 1 1 NPS NPS 15136043 15136043 Paper says nothing - PISA says monomer - automatic transfer from 1szn 1t0u NO 6 6 D3 D3 15003451 15003451 Interface geometry conserved with 1q1g (28%) -- Annotation transfered from 1rxy 1t10 NO 2 2 C2 C2 15206941 15206941 -- Annotation transfered from 1q50 1t18 YES 2 1 NS NPS 15642261 15159559 Sp says monomer - automatic transfer from 1ot9 1t19 YES 2 1 NS NPS 15642261 15159559 Sp says monomer - automatic transfer from 1ot9 1t1a YES 2 1 NS NPS 15642261 15159559 Sp says monomer - automatic transfer from 1ot9 1t1b YES 2 1 NS NPS 15642261 15159559 Sp says monomer - automatic transfer from 1ot9 1t1c YES 2 1 NS NPS 15642261 15159559 Sp says monomer - automatic transfer from 1ot9 1t1d NO 4 4 C4 C4 9886290 9886290 Interface geometry conserved with 3kvt (42%) 1t1f_1 PROBYES 1 2 NPS C2 16973611 15342247 BU changed since last release and is now incorrect - 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization - automaticaly inferred from 1jvq 1t1f_2 PROBYES 1 2 NPS C2 16973611 15342247 BU changed since last release and is now incorrect - 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization - automaticaly inferred from 1jvq 1t1f_3 PROBYES 1 2 NPS C2 16973611 15342247 BU changed since last release and is now incorrect - 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization - automaticaly inferred from 1jvq 1t1g NA 1 2 NPS NS 15242607 12057200 BU changed since last release and is now incorrect - - automaticaly inferred from 1gt9 1t1i NA 1 2 NPS NS 15242607 12057200 BU changed since last release and is now incorrect - - automaticaly inferred from 1gt9 1t24 NO 4 4 D2 D2 15117937 15117937 SP says tetramer -- Annotation transfered from 1ldg 1t25 NO 4 4 D2 D2 15117937 15117937 BU changed since last release and is now corrected - SP says tetramer 1t26 NO 4 4 D2 D2 15117937 15117937 SP says tetramer -- Annotation transfered from 1ldg 1t27 PROBNOT 1 1 NPS NPS 11104777 11980708 This lipid-enclosed state of the protein most probably corresponds to the phospholipid transport intermediate of PITP-alpha. 1t2a PROBNOT 4 4 D2 D2 0 0 Similar proteins are tetramers and PISA says tetramer 1t2c NO 4 4 D2 D2 15117937 15117937 SP says tetramer -- Annotation transfered from 1ldg 1t2d NO 4 4 D2 D2 15117937 15117937 SP says tetramer -- Annotation transfered from 1ldg 1t2e NO 4 4 D2 D2 15117937 15117937 SP says tetramer -- Annotation transfered from 1ldg 1t2f NO 4 4 D2 D2 15117937 15117937 Paper says tetramer - interesting: two isoforms of the enzyme can combine with each other. -- Annotation transfered from 1i0z 1t2h_1 PROBNOT 1 1 NPS NPS 15377518 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1t2h_2 PROBNOT 1 1 NPS NPS 15377518 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1t2i PROBNOT 1 1 NPS NPS 15377518 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1t2n PROBNOT 1 1 NPS NPS 15321721 12077437 PISA says monomer and related proteins are monomeric - automatic transfer from 1isp 1t31 PROBNOT 1 1 NPS NPS 15741158 12614156 Paper says nothing, PISA says monomer - automatic transfer from 1nn6 1t32 PROBNOT 1 1 NPS NPS 15741158 8896442 Paper says nothing - PISA says monomer - automatic transfer from 1cgh 1t36 PROBNOT 8 8 D2 D2 15322282 11551199 Carbamoyl phosphate synthetase (CPS) from Escherichia coli is allosterically regulated by the metabolites ornithine, IMP, and UMP. Ornithine and IMP function as activators, whereas UMP is an inhibitor. CPS undergoes changes in the state of oligomerization that are dependent on the protein concentration and the binding of allosteric effectors. Ornithine and IMP promote the formation of an (ab)4 tetramer while UMP favors the formation of an (ab)2 dimer. Propagate to all (CPS) please! -) -- Annotation transfered from 1bxr 1t37 PROBNOT 1 1 NPS NPS 16278156 16278156 Paper says nothing about oligomer - PISA says monomer -- Annotation transfered from 1td7 1t3a NO 2 2 C2 C2 15157097 15157097 Paper says: The BoNT/E-LC forms a dimer in the crystal and presumably a dimer in solution state also 1t3c NO 2 2 C2 C2 15157097 15157097 Paper says: The BoNT/E-LC forms a dimer in the crystal and presumably a dimer in solution state also -- Annotation transfered from 1t3a 1t3d NO 6 6 D3 D3 15231846 15231846 Paper says: SAT is likely to associate in a hexameric form with 3·2 symmetry; this was supported by chemical cross-linking and gel filtration experiments 1t3e NO 2 2 C2 C2 15201864 15201864 Interface geometry conserved with 1uz5 (32%) 1t3h_1 NA 1 3 NPS C3 0 12538896 BU changed since last release and is now incorrect - NO info - ask crystollographers - automaticaly inferred from 1n3b 1t3h_2 NA 1 3 NPS C3 0 12538896 BU changed since last release and is now incorrect - NO info - ask crystollographers - automaticaly inferred from 1n3b 1t3h_3 NA 1 3 NPS C3 0 12538896 BU changed since last release and is now incorrect - NO info - ask crystollographers - automaticaly inferred from 1n3b 1t3i NO 2 2 C2 C2 15379559 15379559 1t3p NO 1 1 NPS NPS 15306883 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1t40 NO 1 1 NPS NPS 15272156 15272156 SwissProt and PISA say monomer -- Annotation transfered from 1ads 1t41 NO 1 1 NPS NPS 15272156 15272156 SwissProt and PISA say monomer -- Annotation transfered from 1ads 1t43 PROBNOT 1 1 NPS NPS 15223314 15223314 Paper says nothing, EcoCyc and PISA say monomer 1t45 NO 1 1 NPS NPS 15123710 15123710 Paper says: The binding of a stem cell factor dimer to the extracellular Ig domains of c-Kit causes two c-Kit RPTKs to dimerize - ligand induced dimerization 1t46 NO 1 1 NPS NPS 15123710 15123710 Paper says: The binding of a stem cell factor dimer to the extracellular Ig domains of c-Kit causes two c-Kit RPTKs to dimerize - ligand induced dimerization -- Annotation transfered from 1t45 1t47 PROBNOT 2 2 C2 C2 15157070 15157070 SP says dimer - Interface geometry conserved with 1tfz (37%) 1t48 PROBNOT 1 1 NPS NPS 15258570 15258570 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1t49 PROBNOT 1 1 NPS NPS 15258570 15258570 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1t4a YES 4 4 C2 D2 15301532 15301532 Paper says that the D2 form exists in this crystal too -- PISA error: does not find it as stable though but makes it accessible 1t4b NO 2 2 C2 C2 15288787 15288787 1t4d_1 NO 2 2 C2 C2 15288787 15288787 - automatic transfer from 1t4b 1t4d_2 NO 2 2 C2 C2 15288787 15288787 - automatic transfer from 1t4b 1t4e PROBYES 2 1 C2 NPS 15715460 8875929 BU changed since last release and is now incorrect - cf. 1rv1 - automaticaly inferred from 1ycr 1t4f PROBNOT 1 1 NPS NPS 15715460 8875929 cf. 1rv1 - automatic transfer from 1ycr 1t4h PROBYES 2 1 NS NPS 15242606 15242606 Paper let assume a monomeric state 1t4j PROBNOT 1 1 NPS NPS 15258570 15258570 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 1t4m PROBNOT 1 1 NPS NPS 15321721 12077437 PISA says monomer and related proteins are monomeric - automatic transfer from 1isp 1t4p NO 3 3 C3 C3 15248756 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automatic transfer from 1hqx 1t4q PROBNOT 1 1 NPS NPS 15663946 0 SP says monomer - automatic transfer from 21bi 1t4r NO 3 3 C3 C3 15248756 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automatic transfer from 1hqx 1t4s NO 3 3 C3 C3 15248756 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automatic transfer from 1hqx 1t4t NO 3 3 C3 C3 15248756 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automatic transfer from 1hqx 1t5b PROBNOT 2 2 C2 C2 0 0 1t5d NO 2 2 C2 C2 15236575 15236575 Paper says dimer: The CBAL enzyme is a dimer both in solution as well as in the crystalline lattice. -- Annotation transfered from 1t5h 1t5e PROBNOT 13 13 NS NS 15226509 15226509 Paper says: The 13-mer was shaped like a woven rattan cylinder with a large internal tubular space and widely opened flared ends. -- incredible protein shape -- Annotation transfered from 1vf7 1t5f NO 3 3 C3 C3 15315440 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automatic transfer from 1hqx 1t5g NO 3 3 C3 C3 15248756 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automatic transfer from 1hqx 1t5h NO 2 2 C2 C2 15236575 15236575 Paper says dimer: The CBAL enzyme is a dimer both in solution as well as in the crystalline lattice. 1t5k_1 NO 1 1 NPS NPS 15260481 8495197 Amicyanin is a monomeric protein with a molecular weight of 15000 (Husain & Davidson, 1985) - automatic transfer from 1aaj 1t5k_2 NO 1 1 NPS NPS 15260481 8495197 Amicyanin is a monomeric protein with a molecular weight of 15000 (Husain & Davidson, 1985) - automatic transfer from 1aaj 1t5k_3 NO 1 1 NPS NPS 15260481 8495197 Amicyanin is a monomeric protein with a molecular weight of 15000 (Husain & Davidson, 1985) - automatic transfer from 1aaj 1t5k_4 NO 1 1 NPS NPS 15260481 8495197 Amicyanin is a monomeric protein with a molecular weight of 15000 (Husain & Davidson, 1985) - automatic transfer from 1aaj 1t5s NO 1 1 NPS NPS 15192230 15192230 -- Annotation transfered from 1kju 1t5t NO 1 1 NPS NPS 15192230 0 -- Annotation transfered from 1kju 1t5z PROBNOT 1 1 NPS NPS 15563469 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 1t63 PROBNOT 1 1 NPS NPS 15563469 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 1t64_1 NO 1 1 NPS NPS 15242608 15477595 The oligomerization state observed in the crystal is unlikely to occur in solution, because the results of size-exclusion chromatography and light-scattering experiments are compatible with a monomeric state for both the apoprotein and the protein–inhibitor complex. - automatic transfer from 1t67 1t64_2 NO 1 1 NPS NPS 15242608 15477595 The oligomerization state observed in the crystal is unlikely to occur in solution, because the results of size-exclusion chromatography and light-scattering experiments are compatible with a monomeric state for both the apoprotein and the protein–inhibitor complex. - automatic transfer from 1t67 1t65 PROBNOT 1 1 NPS NPS 15563469 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 1t67 NO 1 1 NPS NPS 15242608 15477595 The oligomerization state observed in the crystal is unlikely to occur in solution, because the results of size-exclusion chromatography and light-scattering experiments are compatible with a monomeric state for both the apoprotein and the protein–inhibitor complex. 1t69 NO 1 1 NPS NPS 15242608 15242608 The oligomerization state observed in the crystal is unlikely to occur in solution, because the results of size-exclusion chromatography and light-scattering experiments are compatible with a monomeric state for both the apoprotein and the protein–inhibitor complex. -- Annotation transfered from 1t67 1t6h NO 1 1 NPS NPS 15378068 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1t6n PROBNOT 2 2 C2 C2 15296731 15296731 Paper says: Full-length UAP56 (49 kDa) migrates between a monomer and a dimer on a gel filtration column (70 kDa). UAP56 is likely to migrate abnormally on a gel filtration column due to the existence of the flexible linker. A yeast two-hybrid experiment shows that the most frequent interaction partner for human UAP56 (103 of the total 117 positive clones) is either itself or a close paralogue (DDX39, 91% sequence identity with UAP56), indicating that it exists as a homo- or hetereodimer - however, NOTE that it might be another interface as pointed out in the paper 1t6x PROBYES 2 1 NS NPS 0 0 Enzyme, no reason for that type of interaction, plus this is a thermophile. -- Annotation transfered from 1mrz 1t6y PROBYES 2 1 NS NPS 0 0 Enzyme, no reason for that type of interaction, plus this is a thermophile. -- Annotation transfered from 1mrz 1t6z PROBYES 2 1 NS NPS 0 0 Enzyme, no reason for that type of interaction, plus this is a thermophile. -- Annotation transfered from 1mrz 1t73 PROBNOT 1 1 NPS NPS 15328534 15328534 paper does not mention dimer and PISA says monomer -- Annotation transfered from 1e3g 1t74 PROBNOT 1 1 NPS NPS 15328534 15328534 paper does not mention dimer and PISA says monomer -- Annotation transfered from 1e3g 1t76 PROBNOT 1 1 NPS NPS 15328534 15328534 paper does not mention dimer and PISA says monomer -- Annotation transfered from 1e3g 1t79 PROBNOT 1 1 NPS NPS 15328534 15328534 paper does not mention dimer and PISA says monomer -- Annotation transfered from 1e3g 1t7a PROBNOT 1 1 NPS NPS 15321715 15321715 Paper mentions that BMK M1 are monomeric -- Annotation transfered from 1t7b 1t7b PROBNOT 1 1 NPS NPS 15321715 15321715 Paper mentions that BMK M1 are monomeric 1t7e PROBNOT 1 1 NPS NPS 15321715 15321715 Paper mentions that BMK M1 are monomeric -- Annotation transfered from 1t7b 1t7f PROBNOT 1 1 NPS NPS 15328534 15328534 paper does not mention dimer and PISA says monomer -- Annotation transfered from 1e3g 1t7k NO 2 2 C2 C2 15225729 9083478 - automatic transfer from 1ajx 1t7m PROBNOT 1 1 NPS NPS 15328534 15328534 paper does not mention dimer and PISA says monomer -- Annotation transfered from 1e3g 1t7r PROBNOT 1 1 NPS NPS 15328534 15328534 paper does not mention dimer and PISA says monomer -- Annotation transfered from 1e3g 1t7t PROBNOT 1 1 NPS NPS 15328534 15328534 paper does not mention dimer and PISA says monomer -- Annotation transfered from 1e3g 1t85 PROBNOT 1 1 NPS NPS 15269210 15269210 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 1t86_1 PROBNOT 1 1 NPS NPS 15269210 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1t86_2 PROBNOT 1 1 NPS NPS 15269210 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1t87_1 PROBNOT 1 1 NPS NPS 15269210 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1t87_2 PROBNOT 1 1 NPS NPS 15269210 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1t88_1 PROBNOT 1 1 NPS NPS 15269210 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1t88_2 PROBNOT 1 1 NPS NPS 15269210 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1t8a NO 1 1 NPS NPS 15286283 15286283 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1t8g PROBNOT 1 1 NPS NPS 15340171 8503008 BU changed since last release and is now corrected - Phage T4 Lysosyme is monomeric - automaticaly inferred from 137l 1t8p NO 2 2 C2 C2 15258155 15258155 11038361 and SP say dimer 1t8t NA 2 2 C2 C2 15304505 15304505 Paper says nothing, send email -- Annotation transfered from 1t8u 1t8u NA 2 2 C2 C2 15304505 15304505 Paper says nothing, send email 1t9a NO 2 2 C2 C2 15709745 11902841 Paper says dimer -- interesting: the paper implies that it is closer to tetrameric enzymes of this family rather than to a dimeric one - nice for evolution study - automatic transfer from 1jsc 1t9b NO 2 2 C2 C2 15709745 11902841 Paper says dimer -- interesting: the paper implies that it is closer to tetrameric enzymes of this family rather than to a dimeric one - nice for evolution study - automatic transfer from 1jsc 1t9c NO 2 2 C2 C2 15709745 11902841 Paper says dimer -- interesting: the paper implies that it is closer to tetrameric enzymes of this family rather than to a dimeric one - nice for evolution study - automatic transfer from 1jsc 1t9d_1 NO 2 2 C2 C2 15709745 11902841 Paper says dimer -- interesting: the paper implies that it is closer to tetrameric enzymes of this family rather than to a dimeric one - nice for evolution study - automatic transfer from 1jsc 1t9d_2 NO 2 2 C2 C2 15709745 11902841 Paper says dimer -- interesting: the paper implies that it is closer to tetrameric enzymes of this family rather than to a dimeric one - nice for evolution study - automatic transfer from 1jsc 1t9n PROBNOT 1 1 NPS NPS 15667203 8987974 9000633 says monomeric - automatic transfer from 1uga 1t9o_1 PROBNOT 1 1 NPS NPS 15382226 10555962 BU changed since last release and is now corrected - 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes - automaticaly inferred from 1c09 1t9o_2 PROBNOT 1 1 NPS NPS 15382226 10555962 BU changed since last release and is now corrected - 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes - automaticaly inferred from 1c09 1t9o_3 PROBNOT 1 1 NPS NPS 15382226 10555962 BU changed since last release and is now corrected - 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes - automaticaly inferred from 1c09 1t9p_1 PROBNOT 1 1 NPS NPS 15382226 10555962 BU changed since last release and is now corrected - 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes - automaticaly inferred from 1c09 1t9p_2 PROBNOT 1 1 NPS NPS 15382226 10555962 BU changed since last release and is now corrected - 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes - automaticaly inferred from 1c09 1t9p_3 PROBNOT 1 1 NPS NPS 15382226 10555962 BU changed since last release and is now corrected - 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes - automaticaly inferred from 1c09 1t9q PROBNOT 1 1 NPS NPS 15382226 10555962 BU changed since last release and is now corrected - 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes - automaticaly inferred from 1c09 1t9r PROBNOT 1 1 NPS NPS 15260978 15260978 No info about oligomer in all papers, PISa says monomer and inspection of the structure let think it is right. -- Annotation transfered from 1uho 1t9s_1 PROBNOT 1 1 NPS NPS 15260978 15260978 No info about oligomer in all papers, PISA says monomer - automatic transfer from 1tbf 1t9s_2 PROBNOT 1 1 NPS NPS 15260978 15260978 No info about oligomer in all papers, PISA says monomer - automatic transfer from 1tbf 1ta1 NO 3 3 C3 C3 16266687 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automatic transfer from 1hqx 1ta2 PROBNOT 1 1 NPS NPS 9703466 9703466 -- Annotation transfered from 1doj 1ta4 NO 2 2 C2 C2 15583380 0 - automatic transfer from 1q2x 1ta6 PROBNOT 1 1 NPS NPS 9703466 9703466 -- Annotation transfered from 1doj 1tad_1 PROBNOT 1 1 NPS NPS 7969474 8208289 SP says: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. - automatic transfer from 1tag 1tad_2 PROBNOT 1 1 NPS NPS 7969474 8208289 SP says: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. - automatic transfer from 1tag 1tad_3 PROBNOT 1 1 NPS NPS 7969474 8208289 SP says: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. - automatic transfer from 1tag 1tag PROBNOT 1 1 NPS NPS 8208289 8208289 SP says: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. 1tah_1 PROBNOT 1 1 NPS NPS 8405390 8683577 SP says monomer - PISA too - automatic transfer from 1cvl 1tah_2 PROBNOT 1 1 NPS NPS 8405390 8683577 SP says monomer - PISA too - automatic transfer from 1cvl 1tah_3 PROBNOT 1 1 NPS NPS 8405390 8683577 SP says monomer - PISA too - automatic transfer from 1cvl 1tah_4 PROBNOT 1 1 NPS NPS 8405390 8683577 SP says monomer - PISA too - automatic transfer from 1cvl 1tal NO 1 1 NPS NPS 9232638 9232638 9846867 says monomer -- Annotation transfered from 1p05 1tar NO 2 2 C2 C2 8120903 8120903 Interface geometry conserved with 2ay6 (38%) -- Annotation transfered from 1ivr 1tas NO 2 2 C2 C2 8120903 8120903 Interface geometry conserved with 2ay6 (38%) -- Annotation transfered from 1ivr 1tat NO 2 2 C2 C2 8120903 8120903 Interface geometry conserved with 2ay6 (38%) -- Annotation transfered from 1ivr 1tay NO 1 1 NPS NPS 1390708 1390708 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1tb0 PROBNOT 1 1 NPS NPS 15667203 8987974 9000633 says monomeric - automatic transfer from 1uga 1tb4 NO 2 2 C2 C2 15583380 0 - automatic transfer from 1q2x 1tb6 NA 3 3 NPS NA 15311269 15311269 BU changed since last release and is now incorrect - Email sent -- Annotation transfered from 1sr5 1tb7_1 PROBYES 1 4 NPS D2 15260978 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1tb7_2 PROBYES 1 4 NPS D2 15260978 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1tbb_1 PROBYES 1 4 NPS D2 15260978 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1tbb_2 PROBYES 1 4 NPS D2 15260978 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1tbe PROBNOT 2 2 C2 C2 8107144 8107144 Ubiquitin binds to proteins in different forms that may lead to the degradation of the target protein. For this reason I will consider all the ubiquitin structures to be correct. i.e. different forms may exist. 1tbf PROBNOT 1 1 NPS NPS 15260978 15260978 No info about oligomer in all papers, PISA says monomer 1tbh NO 3 3 C3 C3 16266687 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automatic transfer from 1hqx 1tbj NO 3 3 C3 C3 16266687 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automatic transfer from 1hqx 1tbl NO 3 3 C3 C3 16266687 11278703 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automatic transfer from 1hqx 1tbp NO 2 2 C2 C2 8367480 8367480 Interface geometry conserved with 1mp9 (46%) 1tbt PROBNOT 1 1 NPS NPS 15667203 8987974 9000633 says monomeric - automatic transfer from 1uga 1tbw NA 2 2 C2 C2 15292259 15292259 Paper says dimer is hypothetical - interesting paper because it shows conservation of homo-interfaces at very high divergence 1tby NO 1 1 NPS NPS 1390708 1390708 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1tc0 NA 2 2 NS NS 15292259 15292259 Paper says dimer is hypothetical - interesting paper because it shows conservation of homo-interfaces at very high divergence -- Annotation transfered from 1tc6 1tc1 NO 2 2 C2 C2 9790669 9790669 PID 12070315: Of the 6-oxopurine PRTase structures currently in the literature, four are tetramers (human HGPRT, T. gondii HGXPRT, E. coli XGPRT, and P. falciparum HGXPRT) and three are dimers (G. lamblia GPRT, T. foetus HGXPRT, and T. cruzi HGPRT). -- Annotation transfered from 1p18 1tc2 NO 2 2 C2 C2 9860824 9860824 PID 12070315: Of the 6-oxopurine PRTase structures currently in the literature, four are tetramers (human HGPRT, T. gondii HGXPRT, E. coli XGPRT, and P. falciparum HGXPRT) and three are dimers (G. lamblia GPRT, T. foetus HGXPRT, and T. cruzi HGPRT). -- Annotation transfered from 1p18 1tc6 NA 2 2 NS NS 15292259 15292259 Paper says dimer is hypothetical - interesting paper because it shows conservation of homo-interfaces at very high divergence 1tc8 PROBNOT 1 1 NPS NPS 15659372 15659372 Paper does not discuss oligomeric state - PISA says monomer 1tcd NO 2 2 C2 C2 9761683 9761683 Interface geometry conserved with 1m6j (45%) - paper says dimer -- Annotation transfered from 1ci1 1tcf PROBNOT 1 1 NPS NPS 10651267 10651267 1tcs PROBNOT 1 1 NPS NPS 7634073 7634073 No info, PISA says monomer -- Annotation transfered from 1mrk 1tcw NO 2 2 C2 C2 8756683 8756683 -- Annotation transfered from 1siv 1tcx NO 2 2 C2 C2 8756683 8756683 -- Annotation transfered from 1ajx 1tcy NO 1 1 NPS NPS 1390708 1390708 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1td2 NO 2 2 C2 C2 15547280 15547280 Interface geometry conserved with 1ub0 (23%) 1td7 PROBNOT 1 1 NPS NPS 16301791 16301791 Paper says nothing about oligomer - PISA says monomer 1tda NO 2 2 C2 C2 8343503 8343503 SP says homodimer -- Annotation transfered from 4tms 1tdb NO 2 2 C2 C2 8343503 8343503 SP says homodimer -- Annotation transfered from 4tms 1tdc NO 2 2 C2 C2 8343503 8343503 SP says homodimer -- Annotation transfered from 4tms 1tde NO 2 2 C2 C2 8114095 8114095 Interface conserved with 1fl2 (33%) -- Annotation transfered from 1cl0 1tdf NO 2 2 C2 C2 8114095 8114095 Interface conserved with 1fl2 (33%) -- Annotation transfered from 1cl0 1tdg PROBNOT 1 1 NPS NPS 15518561 14609325 - automatic transfer from 1ong 1tdk NA 1 1 NPS NPS 0 0 No paper found - Paper of the identical sequence 1reo does not mention a dimer - so it is probably a monomer. -- Annotation transfered from 1tdo 1tdl PROBNOT 1 1 NPS NPS 15518561 14609325 - automatic transfer from 1ong 1tdn NA 1 1 NPS NPS 0 0 No paper found - Paper of the identical sequence 1reo does not mention a dimer - so it is probably a monomer. -- Annotation transfered from 1tdo 1tdo NA 1 1 NPS NPS 0 0 No paper found - Paper of the identical sequence 1reo does not mention a dimer - so it is probably a monomer. 1tdu NO 2 2 C2 C2 9687366 9687366 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1tdv PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 1tgm 1tdw YES 1 2 NPS C2 15557004 9843368 BU changed since last release and is now incorrect - - automaticaly inferred from 6pah 1tdy NO 1 1 NPS NPS 1390708 1390708 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1tdz PROBNOT 1 1 NPS NPS 15249553 15249553 SP says monomer and a review says that these prots are monomeric 1te0_1 NO 3 3 C3 C3 15225661 15137941 Interface geometry conserved with 1lcy (31%) - automatic transfer from 1sot 1te0_2 NO 3 3 C3 C3 15225661 15137941 Interface geometry conserved with 1lcy (31%) - automatic transfer from 1sot 1te3 PROBNOT 1 1 NPS NPS 15667203 8987974 9000633 says monomeric - automatic transfer from 1uga 1te6 NO 2 2 C2 C2 15289101 15289101 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific - gene dup - interesting 1teh_1 NO 2 2 C2 C2 9018047 12196016 - automatic transfer from 1m6w 1teh_2 NO 2 2 C2 C2 9018047 12196016 - automatic transfer from 1m6w 1tei_1 PROBNOT 4 4 D2 D2 9451027 0 BU changed since last release and is now corrected - - automaticaly inferred from 1qgl 1tei_2 PROBNOT 4 4 D2 D2 9451027 0 BU changed since last release and is now corrected - - automaticaly inferred from 1qgl 1tem PROBNOT 1 1 NPS NPS -1 0 EcoCyc says monomer -- Annotation transfered from 1jwp 1teq PROBNOT 1 1 NPS NPS 15667203 8987974 9000633 says monomeric - automatic transfer from 1uga 1tes NO 1 1 NPS NPS 8679521 8679521 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1teu PROBNOT 1 1 NPS NPS 15667203 8987974 9000633 says monomeric - automatic transfer from 1uga 1tew NO 1 1 NPS NPS 15299795 0 -- Annotation transfered from 135l 1tf2 NO 1 1 NPS NPS 15256599 15256599 The monomer is real, and due to conformational changes. very interesting example. 1tf5 NO 1 1 NPS NPS 15256599 15256599 The monomer is real, and due to conformational changes. very interesting example. -- Annotation transfered from 1tf2 1tf8 PROBNOT 1 1 NPS NPS 15388919 11484227 SwissProt says monomer - automatic transfer from 1f2o 1tf9 PROBNOT 1 1 NPS NPS 15388919 11484227 SwissProt says monomer - automatic transfer from 1f2o 1tfc NO 2 2 C2 C2 15161930 15161930 Paper says dimer -- Annotation transfered from 1kv6 1tfp YES 2 4 C2 D2 8612621 8612621 1tfu NO 6 6 D3 D3 15322293 15322293 paper says hexamer - ligand binding provokes asymmetry and alters the structure of the solvent channel, so that ligand binding becomes restricted to one trimer - interesting 1tfv NO 1 1 NPS NPS 0 0 Elutes as a monomer - Papers says: The second peak in this final chromatographic step corresponded to a molecular mass of 40 kDa. -- Annotation transfered from 1ljy 1tfw_1 PROBNOT 2 2 C2 C2 15295590 14592988 BU changed since last release and is now corrected - - automaticaly inferred from 1ueu 1tfw_2 PROBNOT 2 2 C2 C2 15295590 14592988 BU changed since last release and is now corrected - - automaticaly inferred from 1ueu 1tfy_1 PROBNOT 2 2 C2 C2 15295590 14592988 BU changed since last release and is now corrected - - automaticaly inferred from 1ueu 1tfy_2 PROBNOT 2 2 C2 C2 15295590 14592988 BU changed since last release and is now corrected - - automaticaly inferred from 1ueu 1tfz PROBNOT 2 2 C2 C2 15301540 15301540 Interface geometry conserved with 1sqi (34%) 1tg1 PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 1tgm 1tg2 YES 1 2 NPS C2 15557004 9843368 BU changed since last release and is now incorrect - - automaticaly inferred from 6pah 1tg4 PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 1tgm 1tg5 PROBNOT 2 2 C2 C2 15301540 15301540 Interface geometry conserved with 1sqi (34%) -- Annotation transfered from 1tfz 1tg8 NO 2 2 C2 C2 15341726 15341726 14737159 says: A three-dimensional structure of the soluble E ectodomain (sE) in its trimeric, postfusion state reveals striking differences from the dimeric, prefusion form. -- Annotation transfered from 1oan 1tgb PROBNOT 1 1 NPS NPS 864704 864704 -- Annotation transfered from 1az8 1tgc PROBNOT 1 1 NPS NPS -1 0 -- Annotation transfered from 1az8 1tgh NO 1 1 NPS NPS 8757291 8757291 Paper says: Photon correlation spectroscopy (PCS) documented that TBP is a dimer in solution in the absence of DNA and undergoes a dimer-to-monomer transition upon binding to oligonucleotides containing the TATA-consensus sequence. - Here there is DNA so it is normal - DNA induced monomer ! -- Annotation transfered from 1cdw 1tgl PROBNOT 1 1 NPS NPS 2304552 2046751 BU changed since last release and is now corrected - Bad structure (only CA) - automaticaly inferred from 5tgl 1tgm PROBNOT 1 1 NPS NPS 0 0 SP says monomer 1tgn PROBNOT 1 1 NPS NPS 556951 556951 -- Annotation transfered from 1az8 1tgt PROBNOT 1 1 NPS NPS -1 0 -- Annotation transfered from 1az8 1tgu PROBNOT 4 4 D2 D2 0 0 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - The BioUnit in the PDB is just wrong. It doesn t make any physical sense - the subunits are separated by 100 Angstroms of empty space. - automaticaly inferred from 7cat 1tgv NO 6 6 D3 D3 0 15003451 Interface geometry conserved with 1q1g (28%) - automatic transfer from 1rxy 1tgy NO 6 6 D3 D3 0 15003451 Interface geometry conserved with 1q1g (28%) - automatic transfer from 1rxy 1th2 PROBNOT 4 4 D2 D2 0 0 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - The BioUnit in the PDB is just wrong. It doesn t make any physical sense - the subunits are separated by 100 Angstroms of empty space. - automaticaly inferred from 7cat 1th3 PROBNOT 4 4 D2 D2 0 0 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - The BioUnit in the PDB is just wrong. It doesn t make any physical sense - the subunits are separated by 100 Angstroms of empty space. - automaticaly inferred from 7cat 1th4 PROBNOT 4 4 D2 D2 0 0 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - The BioUnit in the PDB is just wrong. It doesn t make any physical sense - the subunits are separated by 100 Angstroms of empty space. - automaticaly inferred from 7cat 1th6 PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 1tgm 1th8 NO 4 4 C2 C2 15236958 15236958 Paper says dimer of h-dimers -- Annotation transfered from 1thn 1tha NO 4 4 D2 D2 1730601 1730601 transthyretin is tetrameric -- Annotation transfered from 1fh2 1thc NO 4 4 D2 D2 1631168 1631168 transthyretin is tetrameric -- Annotation transfered from 1fh2 1the PROBYES 2 1 C2 NPS 7890671 7890671 SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) -- Annotation transfered from 1cte 1thf PROBYES 2 1 C2 NPS 10968789 10968789 The HisH and HisF proteins form a stable 1 : 1 dimeric complex that constitutes the IGP synthase holoenzyme. 1thg PROBNOT 1 1 NPS NPS 8464065 8464065 SP says monomer 1thi NO 1 1 NPS NPS 3072690 3072690 Thaumatin is a stable monomeric protein of 22kDa -- Annotation transfered from 1thu 1thj NO 3 3 C3 C3 8665839 8665839 PAper says: The active form of the enzyme is a trimer with three zinc-containing active sites 1thl PROBNOT 1 1 NPS NPS 8286362 8286362 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1thn NO 4 4 C2 C2 15236958 15236958 Paper says dimer of h-dimers 1tho NO 1 1 NPS NPS 0 0 Paper says: Gel-filtration chromatography and polyacrylamide gel electrophoresis suggest that CVWC Trx may exist as both monomers and dimers in solution. In contrast, analytical ultracentrifugation of the CVWC enzyme revealed no significant dimer formation in solution at concentrations up to 30 µM (data not shown). - likely monomer-dimer equilibrium -- Annotation transfered from 1txx 1thu NO 1 1 NPS NPS 15299348 10504569 Thaumatin is a stable monomeric protein of 22kDa 1thv NO 1 1 NPS NPS 15299348 0 Thaumatin is a stable monomeric protein of 22kDa -- Annotation transfered from 1thu 1thw PROBYES 2 1 C2 NPS 15299348 10504569 Thaumatin is a stable monomeric protein of 22kDa 1thx PROBNOT 1 1 NPS NPS 8590004 8590004 Paper says nothing, PISA says monomer 1thy NO 2 2 C2 C2 8371269 8371269 SP says homodimer -- Annotation transfered from 4tms 1ti1 NA 1 1 NPS NPS 15755450 10700276 BU changed since last release and is now corrected - It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant - automaticaly inferred from 1ac1 1tib PROBNOT 1 1 NPS NPS 8014587 11895431 BU changed since last release and is now corrected - Paper does not mention a dimer and PISA says monomer - automaticaly inferred from 1gt6 1tid NO 4 4 C2 C2 15236958 15236958 Paper says dimer of h-dimers -- Annotation transfered from 1thn 1tik PROBNOT 2 2 C2 C2 0 0 1tim NO 2 2 C2 C2 985462 985462 BU changed since last release and is now corrected - -- Supperposed structures 1tio PROBNOT 1 1 NPS NPS 9920392 9920392 -- Annotation transfered from 1az8 1tip PROBNOT 2 2 C2 C2 9253407 9253407 Paper says: the bisphosphatase dimerizes at high protein concentrations. We believe that the two subunits found in the crystallographic asymmetric unit may represent the dimeric form of the bisphosphatase domain and perhaps the interface contained in the bifunctional enzyme. -- Annotation transfered from 1fbt 1tis NO 2 2 C2 C2 7803410 7803410 1tj9 PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 1tgm 1tjk PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 1tgm 1tjm PROBNOT 1 1 NPS NPS 15340165 15340165 paper do not speak about any olig. state, PISA says monomer. 1tjo NO 12 12 Tetr Tetr 15365182 15365182 Interface geometry conserved with 1o9r (25%) - automatic transfer from 1moj 1tjq PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 1tgm 1tjs NO 2 2 C2 C2 9687366 9687366 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1tju NO 4 4 D2 D2 15320872 15320872 Interface geometry conserved with 1fur (23%) -- Annotation transfered from 1tjw 1tjv NO 4 4 D2 D2 15320872 15320872 Interface geometry conserved with 1fur (23%) -- Annotation transfered from 1tjw 1tjw NO 4 4 D2 D2 15320872 15320872 Interface geometry conserved with 1fur (23%) 1tjx PROBNOT 1 1 NPS NPS 15340165 15340165 paper do not speak about any olig. state, PISA says monomer. - automatic transfer from 1tjm 1tk1 PROBYES 1 2 NPS C2 15194705 15194705 SwissProt says homodimer 1tk2 NO 1 1 NPS NPS 0 0 -- Annotation transfered from 1c9n 1tk3 NO 2 2 C2 C2 15175333 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. -- Annotation transfered from 1tkr 1tk4 PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 1tgm 1tk6 NO 12 12 Tetr Tetr 15365182 15365182 Interface geometry conserved with 1o9r (25%) - automatic transfer from 1moj 1tk9 NO 4 4 D2 D2 16477602 0 Interface geometry conserved with 1jeo (43%) 1tkf PROBNOT 1 1 NPS NPS 0 11484227 SwissProt says monomer - automatic transfer from 1f2o 1tkh PROBNOT 1 1 NPS NPS 0 11484227 SwissProt says monomer - automatic transfer from 1f2o 1tki YES 2 1 C2 NPS 9804419 9804419 BU changed since last release and is now incorrect - Part of a gigantic molecule (titin) 1tkj PROBNOT 1 1 NPS NPS 0 11484227 SwissProt says monomer - automatic transfer from 1f2o 1tkk NO 8 8 D4 D4 15301535 15301535 1tkl PROBNOT 2 2 C2 C2 15194705 15194705 1tko NO 12 12 Tetr Tetr 15365182 15365182 Interface geometry conserved with 1o9r (25%) - automatic transfer from 1moj 1tkp NO 12 12 Tetr Tetr 15365182 15365182 Interface geometry conserved with 1o9r (25%) - automatic transfer from 1moj 1tkr NO 2 2 C2 C2 15175333 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. 1tla NO 1 1 NPS NPS 8401213 8401213 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 1tlb_1 PROBNOT 2 2 C2 C2 15194705 15194705 - automatic transfer from 1tkl 1tlb_2 PROBNOT 2 2 C2 C2 15194705 15194705 - automatic transfer from 1tkl 1tlb_3 PROBNOT 2 2 C2 C2 15194705 15194705 - automatic transfer from 1tkl 1tlc NO 2 2 C2 C2 7724588 7724588 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1tld PROBNOT 1 1 NPS NPS 2614845 2614845 -- Annotation transfered from 1az8 1tlf NO 4 4 C2 C2 7792597 7792597 -- Annotation transfered from 1lbh 1tlg NO 2 2 C2 C2 10398588 10398588 Analytical ultracentrifugation revealed that TC14 behaves as a dimer in solution. 1tli PROBNOT 2 2 C2 C2 10651278 10651278 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 8tln 1tlk PROBNOT 2 2 C2 C2 1404391 9078244 telokin was present in the form of a dimer. 1tlm NO 4 4 D2 D2 8454595 8454595 transthyretin is tetrameric -- Annotation transfered from 1fh2 1tlp PROBNOT 1 1 NPS NPS 3709536 3709536 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1tls NO 2 2 C2 C2 9109668 9109668 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1tlt NO 4 4 D2 D2 0 0 Interface geometry conserved with 1h6b (20%) 1tlx PROBNOT 1 1 NPS NPS 10651278 10651278 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1tmk NO 2 2 C2 C2 9253404 9253404 Low similarity to other homodimers but interface geometry conserved -- Annotation transfered from 2tmk 1tml NA 1 2 NPS C2 8399160 8399160 Full size protein is dimeric (cf. SP references), I dont know wether this fragment should be as well. 1tmn PROBNOT 1 1 NPS NPS 6395881 6395881 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 1tmy NO 1 1 NPS NPS 9521117 9521117 Paper says monomer - very interesting paper btw 1tn0_1 YES 1 3 NPS C3 15312757 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1tn0_2 YES 1 3 NPS C3 15312757 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1tn4 PROBNOT 1 1 NPS NPS 9438870 9438870 -- Annotation transfered from 1tcf 1tn5_1 YES 1 3 NPS C3 15312757 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1tn5_2 YES 1 3 NPS C3 15312757 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1tnd_1 PROBNOT 1 1 NPS NPS 8259210 8208289 SP says: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. - automatic transfer from 1tag 1tnd_2 PROBNOT 1 1 NPS NPS 8259210 8208289 SP says: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. - automatic transfer from 1tag 1tnd_3 PROBNOT 1 1 NPS NPS 8259210 8208289 SP says: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. - automatic transfer from 1tag 1tnf NO 3 3 C3 C3 2551905 2551905 SP and paper say trimer -- Annotation transfered from 4tsv 1tng PROBNOT 1 1 NPS NPS 7634078 7634078 -- Annotation transfered from 1az8 1tnh PROBNOT 1 1 NPS NPS 7634078 7634078 -- Annotation transfered from 1az8 1tni PROBNOT 1 1 NPS NPS 7634078 7634078 -- Annotation transfered from 1az8 1tnj PROBNOT 1 1 NPS NPS 7634078 7634078 -- Annotation transfered from 1az8 1tnk PROBNOT 1 1 NPS NPS 7634078 7634078 -- Annotation transfered from 1az8 1tnl PROBNOT 1 1 NPS NPS 7634078 7634078 -- Annotation transfered from 1az8 1toe NO 2 2 C2 C2 15461450 7896726 Interface geometry conserved with 2ay6 (45%) - automatic transfer from 1amr 1tog NO 2 2 C2 C2 15461450 7896726 Interface geometry conserved with 2ay6 (45%) - automatic transfer from 1amr 1toh NO 4 4 D2 D2 9228951 9228951 Paper says tetramer - interesting: highly linked to disease. 1toi NO 2 2 C2 C2 15461450 7896726 Interface geometry conserved with 2ay6 (45%) - automatic transfer from 1amr 1toj NO 2 2 C2 C2 15461450 7896726 Interface geometry conserved with 2ay6 (45%) - automatic transfer from 1amr 1tok NO 2 2 C2 C2 15461450 7896726 Interface geometry conserved with 2ay6 (45%) - automatic transfer from 1amr 1ton PROBNOT 1 1 NPS NPS 2821276 2821276 SP says monomer 1too PROBNOT 1 1 NPS NPS 15663946 0 SP says monomer - automatic transfer from 21bi 1top PROBNOT 1 1 NPS NPS 15299475 0 -- Annotation transfered from 1ncx 1tou PROBNOT 1 1 NPS NPS 15357970 15357970 PAper says nothing, PISA says monomer 1tow PROBNOT 1 1 NPS NPS 15357969 0 PAper says nothing, PISA says monomer -- Annotation transfered from 1tou 1tp2 PROBYES 2 1 NS NPS 0 0 SP says monomer -- Annotation transfered from 1oxl 1tpb NO 2 2 C2 C2 7577950 7577950 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1sq7 1tpc NO 2 2 C2 C2 7577950 7577950 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1sq7 1tpd_1 PROBNOT 2 2 C2 C2 8356028 2062828 SP says dimer - automatic transfer from 6tim 1tpd_2 PROBNOT 2 2 C2 C2 8356028 2062828 SP says dimer - automatic transfer from 6tim 1tpe PROBNOT 2 2 C2 C2 8061607 8061607 SP says dimer -- Annotation transfered from 6tim 1tpf PROBNOT 2 2 C2 C2 8061607 8061607 SP says dimer -- Annotation transfered from 6tim 1tph NO 2 2 C2 C2 8130195 8130195 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1sq7 1tpo PROBNOT 1 1 NPS NPS -1 0 -- Annotation transfered from 1az8 1tpp PROBNOT 1 1 NPS NPS -1 0 -- Annotation transfered from 1az8 1tps PROBNOT 1 1 NPS NPS 9383379 9383379 -- Annotation transfered from 1az8 1tpu NO 2 2 C2 C2 8952501 8952501 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1sq7 1tpv NO 2 2 C2 C2 8952501 8952501 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1sq7 1tpw NO 2 2 C2 C2 10194358 0 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1sq7 1tq9 NO 2 2 C2 C2 15192098 15192098 -- Annotation transfered from 11ba 1tqh YES 1 2 NPS C2 15327954 15327954 Paper says enzyme active as a dimer (PISA wrong) 1tqj NO 6 6 D3 D3 15333955 0 Interface geometry conserved with 1rpx 1tqn PROBNOT 1 1 NPS NPS 15258162 15258162 Paper says nothing - 11304120 says P450s are monomeric enzymes -- Annotation transfered from 1w0e 1tqo NO 1 1 NPS NPS 15276844 15276844 Paper says monomeric -- Annotation transfered from 1ena 1tr1 PROBNOT 8 8 D4 D4 9466926 9466926 Biochemical characterization of BglA showed that the native protein is an intracellular enzyme with an octameric configuration and a molecular mass of about 400,000 Da [Sanz-Aparicio et al 1994]. 1tr5 NO 1 1 NPS NPS 15276844 15276844 Paper says monomeric -- Annotation transfered from 1ena 1trb NO 2 2 C2 C2 2067578 2067578 Interface conserved with 1fl2 (33%) -- Annotation transfered from 1cl0 1trd_1 PROBNOT 2 2 C2 C2 8356028 2062828 SP says dimer - automatic transfer from 6tim 1trd_2 PROBNOT 2 2 C2 C2 8356028 2062828 SP says dimer - automatic transfer from 6tim 1tre NO 2 2 C2 C2 15299515 15299515 Interface geometry conserved with 1m6j (43%) - paper says dimer 1trg NO 2 2 C2 C2 9687366 9687366 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1trh NO 1 1 NPS NPS 8142901 8142901 interesting: change of oligomeric state is associated with activity - the open form of the lipase is found to be present in solution as a dimer, whereas the closed form appears to be a monomer (pid=11084600). 1tri NO 1 1 NPS NPS 16100954 16100954 Paper says this is an engineered monomeric TIM 1trm PROBYES 2 1 NS NPS 3112942 3112942 Trypsin is monomeric 1tro_1 NO 2 2 C2 C2 3419502 0 - automatic transfer from 1jhg 1tro_2 NO 2 2 C2 C2 3419502 0 - automatic transfer from 1jhg 1trr_1 PROBYES 4 2 C2 C2 8232559 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1jhg 1trr_2 PROBYES 4 2 C2 C2 8232559 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1jhg 1try PROBNOT 1 1 NPS NPS 15299338 0 -- Annotation transfered from 1gdn 1ts0 YES 2 1 NS NPS 15870207 15159559 Sp says monomer - automatic transfer from 1ot9 1ts6 YES 2 1 NS NPS 15870207 15159559 Sp says monomer - automatic transfer from 1ot9 1ts7 YES 3 1 NS NPS 15870207 15159559 BU changed since last release and is now incorrect - Sp says monomer - automaticaly inferred from 1ot9 1ts8 YES 2 1 NS NPS 15870207 15159559 Sp says monomer - automatic transfer from 1ot9 1tsd NO 2 2 C2 C2 8846221 8846221 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1tsh NO 4 4 D2 D2 9818054 9818054 transthyretin is tetrameric -- Annotation transfered from 1fh2 1tsi PROBNOT 2 2 C2 C2 1304889 1304889 SP says dimer -- Annotation transfered from 6tim 1tsl NO 2 2 C2 C2 9931028 9931028 SP says homodimer -- Annotation transfered from 4tms 1tsm NO 2 2 C2 C2 9931028 9931028 SP says homodimer -- Annotation transfered from 4tms 1tsn NO 2 2 C2 C2 9109668 9109668 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1tsp NO 3 3 C3 C3 8023158 8023158 Paper says trimer -- Annotation transfered from 1tyw 1tsr NA 3 4 NS C2 8023157 8023157 I am not sure about that one. 9628871 shows a cartoon of how it bind. Normally, there are 2 palindromic sequences, but in the crystal structure there are only 3 proteins, and the binding mode seems not compatible with that shown in 9628871 1tsv NO 2 2 C2 C2 9053905 9053905 SP says homodimer -- Annotation transfered from 4tms 1tsw NO 2 2 C2 C2 9053905 9053905 SP says homodimer -- Annotation transfered from 4tms 1tsx NO 2 2 C2 C2 9053905 9053905 SP says homodimer -- Annotation transfered from 4tms 1tsy NO 2 2 C2 C2 9053905 9053905 SP says homodimer -- Annotation transfered from 4tms 1tsz NO 2 2 C2 C2 9053905 9053905 SP says homodimer -- Annotation transfered from 4tms 1tt2 NO 1 1 NPS NPS 15276844 15276844 Paper says monomeric -- Annotation transfered from 1ena 1tt6 NO 4 4 D2 D2 15469931 11106758 - automatic transfer from 1g1o 1tta NO 4 4 D2 D2 8428915 8428915 transthyretin is tetrameric -- Annotation transfered from 1fh2 1ttb NO 4 4 D2 D2 8428915 8428915 transthyretin is tetrameric -- Annotation transfered from 1fh2 1ttc NO 4 4 D2 D2 8428915 8428915 transthyretin is tetrameric -- Annotation transfered from 1fh2 1tth NO 12 12 D3 D3 15288791 15288791 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1tti NO 1 1 NPS NPS 8591044 8591044 Paper says this is a monomeric variant 1ttj NO 1 1 NPS NPS 8591044 8591044 Paper says this is a monomeric variant 1ttm PROBNOT 1 1 NPS NPS 15453828 8987974 9000633 says monomeric - automatic transfer from 1uga 1ttp NO 4 4 C2 C2 8672457 8672457 Paper says a2b2 -- Annotation transfered from 2wsy 1ttq NO 4 4 C2 C2 8672457 8672457 Paper says a2b2 -- Annotation transfered from 2wsy 1ttr PROBYES 2 4 C2 D2 15299606 0 All dimers similar to that one are found to be tetramers by PISA. Because the native structure is tetrameric, dimer are certainly mistakes -- Annotation transfered from 1bmz 1ttz PROBNOT 1 1 NPS NPS 0 0 No paper - PISA says monomer 1tu0 NO 12 12 D3 D3 15288791 15288791 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1tu4_1 NO 1 1 NPS NPS 15378032 0 - automatic transfer from 1r2q 1tu4_2 NO 1 1 NPS NPS 15378032 0 - automatic transfer from 1r2q 1tu4_3 NO 1 1 NPS NPS 15378032 0 - automatic transfer from 1r2q 1tu4_4 NO 1 1 NPS NPS 15378032 0 - automatic transfer from 1r2q 1tu6 YES 2 1 NS NPS 15341947 15341947 All other members are monomers and paper does not mentions a dimer. 1tuc PROBNOT 1 1 NPS NPS 7723022 7723022 -- Annotation transfered from 1neg 1tud PROBNOT 1 1 NPS NPS 7723022 7723022 -- Annotation transfered from 1neg 1tug NO 12 12 D3 D3 15288791 15288791 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 1tui YES 3 1 NS NPS 8939739 9838020 EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa 1tup NA 3 4 NS C2 8023157 8023157 I am not sure about that one. 9628871 shows a cartoon of how it bind. Normally, there are 2 palindromic sequences, but in the crystal structure there are only 3 proteins, and the binding mode seems not compatible with that shown in 9628871 -- Annotation transfered from 1tsr 1tvd NO 2 2 C2 C2 9461220 9461220 Paper says: the ES204 Vd domain exists as a homodimer both in solution and in the crystal structure. 1tvu NO 2 2 C2 C2 9514716 9514716 SP says homodimer -- Annotation transfered from 4tms 1tvv NO 2 2 C2 C2 9514716 9514716 SP says homodimer -- Annotation transfered from 4tms 1tvw NO 2 2 C2 C2 9514716 9514716 SP says homodimer -- Annotation transfered from 4tms 1tvx PROBNOT 4 4 D2 D2 9047370 9047370 Paper and PISA say tetramer 1tvy_1 PROBNOT 1 1 NPS NPS 15449940 12927542 Paper says nothing, PISA says monomer - automatic transfer from 1pzt 1tvy_2 PROBNOT 1 1 NPS NPS 15449940 12927542 Paper says nothing, PISA says monomer - automatic transfer from 1pzt 1tvz NO 2 2 C2 C2 15292254 15292254 1tw1_1 PROBNOT 1 1 NPS NPS 15449940 12927542 Paper says nothing, PISA says monomer - automatic transfer from 1pzt 1tw1_2 PROBNOT 1 1 NPS NPS 15449940 12927542 Paper says nothing, PISA says monomer - automatic transfer from 1pzt 1tw2 NO 2 2 C2 C2 15273252 15273252 Interface geometry conserved with 1r00 (50% id) 1tw3 NO 2 2 C2 C2 15273252 15273252 Interface geometry conserved with 1r00 (50% id) -- Annotation transfered from 1tw2 1tw5_1 PROBNOT 1 1 NPS NPS 15449940 12927542 Paper says nothing, PISA says monomer - automatic transfer from 1pzt 1tw5_2 PROBNOT 1 1 NPS NPS 15449940 12927542 Paper says nothing, PISA says monomer - automatic transfer from 1pzt 1twa NO 10 10 NPS NPS 15537538 11313498 Correct complex. -- Annotation transfered from 1i3q 1twc NO 10 10 NPS NPS 15537538 11313498 Correct complex. -- Annotation transfered from 1i3q 1twe PROBNOT 1 1 NPS NPS 15663946 0 SP says monomer - automatic transfer from 21bi 1twf NO 10 10 NPS NPS 15537538 11313498 Correct complex. -- Annotation transfered from 1i3q 1twg NO 10 10 NPS NPS 15537538 11313498 Correct complex. -- Annotation transfered from 1i3q 1twh NO 10 10 NPS NPS 15537538 11313498 Correct complex. -- Annotation transfered from 1i3q 1twj PROBNOT 4 4 D2 D2 15301532 15301532 Paper says tetramer has been observed in solution 1twm PROBNOT 1 1 NPS NPS 15663946 0 SP says monomer - automatic transfer from 21bi 1tx7 PROBNOT 1 1 NPS NPS 11738605 0 - automatic transfer from 1az8 1tx8 PROBNOT 1 1 NPS NPS 15380220 0 - automatic transfer from 1az8 1txi PROBNOT 1 1 NPS NPS 15728261 11344298 paper says nothing, PISA says monomer - automatic transfer from 1ie9 1txn PROBNOT 2 2 C2 C2 0 15194705 - automatic transfer from 1tkl 1txr NO 1 1 NPS NPS 15274616 15274616 Aminopeptidase from Aeromonas proteolytica (AAP) is a small, monomeric enzyme (32KDa) -- Annotation transfered from 1cp6 1txt_1 NO 2 2 C2 C2 15292254 15292254 - automatic transfer from 1tvz 1txt_2 NO 2 2 C2 C2 15292254 15292254 - automatic transfer from 1tvz 1txx NO 1 1 NPS NPS 10489448 10489448 Paper says: Gel-filtration chromatography and polyacrylamide gel electrophoresis suggest that CVWC Trx may exist as both monomers and dimers in solution. In contrast, analytical ultracentrifugation of the CVWC enzyme revealed no significant dimer formation in solution at concentrations up to 30 µM (data not shown). - likely monomer-dimer equilibrium 1tyn PROBNOT 1 1 NPS NPS -1 0 -- Annotation transfered from 1az8 1typ NO 2 2 C2 C2 8477734 8477734 GR are homodimers 1tyr PROBYES 2 4 C2 D2 8536704 8536704 All dimers similar to that one are found to be tetramers by PISA. Because the native structure is tetrameric, dimer are certainly mistakes -- Annotation transfered from 1bmz 1tys NO 2 2 C2 C2 8312270 8312270 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1tyt NO 2 2 C2 C2 15299452 0 GR are homodimers -- Annotation transfered from 1typ 1tyu NO 3 3 C3 C3 8855221 8855221 Paper says trimer -- Annotation transfered from 1tyw 1tyv NO 3 3 C3 C3 8855221 8855221 Paper says trimer -- Annotation transfered from 1tyw 1tyw NO 3 3 C3 C3 8855221 8855221 Paper says trimer 1tyx NO 3 3 C3 C3 8855221 8855221 Paper says trimer -- Annotation transfered from 1tyw 1tz0 YES 3 2 C3 C2 0 0 Interface geometry conserved with 1iuj (32%) 1tz8_1 NO 4 4 D2 D2 15469931 11106758 - automatic transfer from 1g1o 1tz8_2 NO 4 4 D2 D2 15469931 11106758 - automatic transfer from 1g1o 1tze NO 1 1 NPS NPS 8673601 8673601 -- Annotation transfered from 1zfp 1tzf NO 6 6 D3 D3 15292268 15292268 Paper says: Analytical ultracentrifugation experiments confirmed the hexameric nature of the enzyme. [...]. Previous gel filtration analyses of the Y. pseudotuberculosis cytidylyltransferase, which is 80% identical in amino acid sequence to the Salmonella enzyme, suggested that the protein exists as a tetramer, which is similar to the thymidylyltransferases -- interesting: hexamer-tetramer related at 80% id! 1tzq NO 1 1 NPS NPS 15322132 15322132 SP says: Tetramer in the presence of a lipidic interface. Monomer, in soluble state - Since this is the soluble state, it should be a monomer. - very interesting protein: membrane induced tetramerization 1tzt_1 NO 1 1 NPS NPS 15279620 15279620 Paper says: NusB is a prokaryotic transcription factor involved in antitermination processes, during which it interacts with the boxA portion of the mRNA nut site. Previous studies have shown that NusB exhibits an all-helical fold, and that the protein from Escherichia coli forms monomers, while Mycobacterium tuberculosis NusB is a dimer. The functional significance of NusB dimerization is unknown. We have determined five crystal structures of NusB from Thermotoga maritima. In three crystal forms the protein appeared monomeric, whereas the two other crystal forms contained assemblies, which resembled the M. tuberculosis dimers. In solution, T. maritima NusB could be cross-linked as dimers, but it migrated as a monomer in gel-filtration analyses, suggesting a monomer dimer equilibrium with a preference for the monomer. - automatic transfer from 1tzv 1tzt_2 NO 1 1 NPS NPS 15279620 15279620 Paper says: NusB is a prokaryotic transcription factor involved in antitermination processes, during which it interacts with the boxA portion of the mRNA nut site. Previous studies have shown that NusB exhibits an all-helical fold, and that the protein from Escherichia coli forms monomers, while Mycobacterium tuberculosis NusB is a dimer. The functional significance of NusB dimerization is unknown. We have determined five crystal structures of NusB from Thermotoga maritima. In three crystal forms the protein appeared monomeric, whereas the two other crystal forms contained assemblies, which resembled the M. tuberculosis dimers. In solution, T. maritima NusB could be cross-linked as dimers, but it migrated as a monomer in gel-filtration analyses, suggesting a monomer dimer equilibrium with a preference for the monomer. - automatic transfer from 1tzv 1tzu NO 1 1 NPS NPS 15279620 15279620 Paper says: NusB is a prokaryotic transcription factor involved in antitermination processes, during which it interacts with the boxA portion of the mRNA nut site. Previous studies have shown that NusB exhibits an all-helical fold, and that the protein from Escherichia coli forms monomers, while Mycobacterium tuberculosis NusB is a dimer. The functional significance of NusB dimerization is unknown. We have determined five crystal structures of NusB from Thermotoga maritima. In three crystal forms the protein appeared monomeric, whereas the two other crystal forms contained assemblies, which resembled the M. tuberculosis dimers. In solution, T. maritima NusB could be cross-linked as dimers, but it migrated as a monomer in gel-filtration analyses, suggesting a monomer dimer equilibrium with a preference for the monomer. -- Annotation transfered from 1tzv 1tzv NO 1 1 NPS NPS 15279620 15279620 Paper says: NusB is a prokaryotic transcription factor involved in antitermination processes, during which it interacts with the boxA portion of the mRNA nut site. Previous studies have shown that NusB exhibits an all-helical fold, and that the protein from Escherichia coli forms monomers, while Mycobacterium tuberculosis NusB is a dimer. The functional significance of NusB dimerization is unknown. We have determined five crystal structures of NusB from Thermotoga maritima. In three crystal forms the protein appeared monomeric, whereas the two other crystal forms contained assemblies, which resembled the M. tuberculosis dimers. In solution, T. maritima NusB could be cross-linked as dimers, but it migrated as a monomer in gel-filtration analyses, suggesting a monomer dimer equilibrium with a preference for the monomer. 1tzw NO 1 1 NPS NPS 15279620 15279620 Paper says: NusB is a prokaryotic transcription factor involved in antitermination processes, during which it interacts with the boxA portion of the mRNA nut site. Previous studies have shown that NusB exhibits an all-helical fold, and that the protein from Escherichia coli forms monomers, while Mycobacterium tuberculosis NusB is a dimer. The functional significance of NusB dimerization is unknown. We have determined five crystal structures of NusB from Thermotoga maritima. In three crystal forms the protein appeared monomeric, whereas the two other crystal forms contained assemblies, which resembled the M. tuberculosis dimers. In solution, T. maritima NusB could be cross-linked as dimers, but it migrated as a monomer in gel-filtration analyses, suggesting a monomer dimer equilibrium with a preference for the monomer. -- Annotation transfered from 1tzv 1tzx_1 NO 1 1 NPS NPS 15279620 15279620 Paper says: NusB is a prokaryotic transcription factor involved in antitermination processes, during which it interacts with the boxA portion of the mRNA nut site. Previous studies have shown that NusB exhibits an all-helical fold, and that the protein from Escherichia coli forms monomers, while Mycobacterium tuberculosis NusB is a dimer. The functional significance of NusB dimerization is unknown. We have determined five crystal structures of NusB from Thermotoga maritima. In three crystal forms the protein appeared monomeric, whereas the two other crystal forms contained assemblies, which resembled the M. tuberculosis dimers. In solution, T. maritima NusB could be cross-linked as dimers, but it migrated as a monomer in gel-filtration analyses, suggesting a monomer dimer equilibrium with a preference for the monomer. - automatic transfer from 1tzv 1tzx_2 NO 1 1 NPS NPS 15279620 15279620 Paper says: NusB is a prokaryotic transcription factor involved in antitermination processes, during which it interacts with the boxA portion of the mRNA nut site. Previous studies have shown that NusB exhibits an all-helical fold, and that the protein from Escherichia coli forms monomers, while Mycobacterium tuberculosis NusB is a dimer. The functional significance of NusB dimerization is unknown. We have determined five crystal structures of NusB from Thermotoga maritima. In three crystal forms the protein appeared monomeric, whereas the two other crystal forms contained assemblies, which resembled the M. tuberculosis dimers. In solution, T. maritima NusB could be cross-linked as dimers, but it migrated as a monomer in gel-filtration analyses, suggesting a monomer dimer equilibrium with a preference for the monomer. - automatic transfer from 1tzv 1u05 PROBYES 2 1 C2 NPS 0 0 The monomeric character was confirmed by size-exclusion chromatography -- Annotation transfered from 1xaf 1u06 PROBNOT 1 1 NPS NPS 15928996 15185962 - automatic transfer from 1neg 1u08 NO 2 2 C2 C2 15280032 15280032 1u0k NO 2 2 C2 C2 0 0 No paper but interface conserved down to 1qya (30% id) so interface is certainly real. 1u0m NO 2 2 C2 C2 15265863 15265863 1u0y NA 1 1 NPS NPS 0 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 1u0z_1 NA 1 1 NPS NPS 0 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 1u0z_2 NA 1 1 NPS NPS 0 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 1u13 PROBNOT 1 1 NPS NPS 0 0 11304120 says P450s are monomeric enzymes 1u15 NO 4 4 D2 D2 15362851 11258884 Interface geometry conserved with 1fur (23%) - automatic transfer from 1hy0 1u16 NO 4 4 D2 D2 15362851 11258884 Interface geometry conserved with 1fur (23%) - automatic transfer from 1hy0 1u1b_1 PROBNOT 1 1 NPS NPS 15969595 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1u1b_2 PROBNOT 1 1 NPS NPS 15969595 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1u1c NO 6 6 D3 D3 15983408 15003451 Interface geometry conserved with 1q1g (28%) - automatic transfer from 1rxy 1u1d NO 6 6 D3 D3 15983408 15003451 Interface geometry conserved with 1q1g (28%) - automatic transfer from 1rxy 1u1e NO 6 6 D3 D3 15983408 15003451 Interface geometry conserved with 1q1g (28%) - automatic transfer from 1rxy 1u1f NO 6 6 D3 D3 15983408 15003451 Interface geometry conserved with 1q1g (28%) - automatic transfer from 1rxy 1u1g NO 6 6 D3 D3 15983408 15003451 Interface geometry conserved with 1q1g (28%) - automatic transfer from 1rxy 1u1i NO 4 4 D2 D2 15628862 15628862 Paper says tetramer 1u1k PROBNOT 1 1 NPS NPS 15342234 15342234 Paper says nothing - DNA seems to create artificial dimers (this is a fragment half the size of the protein) -- SCOP error: two domains; not one only -- Annotation transfered from 1u1r 1u1l PROBNOT 1 1 NPS NPS 15342234 15342234 Paper says nothing - DNA seems to create artificial dimers (this is a fragment half the size of the protein) -- SCOP error: two domains; not one only -- Annotation transfered from 1u1r 1u1m PROBNOT 1 1 NPS NPS 15342234 15342234 Paper says nothing - DNA seems to create artificial dimers (this is a fragment half the size of the protein) -- SCOP error: two domains; not one only -- Annotation transfered from 1u1r 1u1n PROBNOT 1 1 NPS NPS 15342234 15342234 Paper says nothing - DNA seems to create artificial dimers (this is a fragment half the size of the protein) -- SCOP error: two domains; not one only -- Annotation transfered from 1u1r 1u1o PROBNOT 1 1 NPS NPS 15342234 15342234 Paper says nothing - DNA seems to create artificial dimers (this is a fragment half the size of the protein) -- SCOP error: two domains; not one only -- Annotation transfered from 1u1r 1u1p PROBNOT 1 1 NPS NPS 15342234 15342234 Paper says nothing - DNA seems to create artificial dimers (this is a fragment half the size of the protein) -- SCOP error: two domains; not one only -- Annotation transfered from 1u1r 1u1q PROBNOT 1 1 NPS NPS 15342234 15342234 Paper says nothing - DNA seems to create artificial dimers (this is a fragment half the size of the protein) -- SCOP error: two domains; not one only -- Annotation transfered from 1u1r 1u1r PROBNOT 1 1 NPS NPS 15342234 15342234 Paper says nothing - DNA seems to create artificial dimers (this is a fragment half the size of the protein) -- SCOP error: two domains; not one only 1u1z NO 6 6 D3 D3 15371447 15371447 Paper says: Our studies on His-tagged EcFabZ also indicate a hexameric state in solution; the elution behavior from a gel filtration column corresponds to a Stokes radius appropriate for a 112-kDa globular assembly. Previously reported non-denaturing gel electrophoresis results for EcFabZ are also consistent with a hexamer (25). In contrast, the FabZ orthologue in the P. falciparum type II fatty acid synthase (PfFabZ) is reported to be dimeric by both dynamic light scattering and gel filtration criteria 1u21 NO 4 4 D2 D2 15826192 11106758 - automatic transfer from 1g1o 1u2o_1 NA 1 1 NPS NPS 12970348 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 1u2o_2 NA 1 1 NPS NPS 12970348 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 1u3a NA 4 1 NS NPS 15755450 10700276 BU changed since last release and is now incorrect - It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant - automaticaly inferred from 1ac1 1u3q_1 PROBNOT 2 2 C2 C2 15456246 0 - automatic transfer from 1qkm 1u3s PROBNOT 2 2 C2 C2 15456246 0 - automatic transfer from 1qkm 1u3t NO 2 2 C2 C2 15449945 11274460 Dimer of identical or non-identical chains of three types - gene dup - interesting - automatic transfer from 1hso 1u3u NO 2 2 C2 C2 15449945 8201622 Dimer of identical or non-identical chains of three types - gene dup - interesting - automatic transfer from 1hdx 1u3v NO 2 2 C2 C2 15449945 8201622 Dimer of identical or non-identical chains of three types - gene dup - interesting - automatic transfer from 1hdx 1u3w NO 2 2 C2 C2 15449945 11274460 Dimer of identical or non-identical chains of three types - gene dup - interesting - automatic transfer from 1ht0 1u4j NO 2 2 C2 C2 15721580 15721580 Paper says dimer - carbohydrate induced homodimer - interesting 1u4l PROBNOT 2 2 C2 C2 15530372 0 Paper implies it is a dimer - automatic transfer from 1eqt 1u4m PROBNOT 2 2 C2 C2 15530372 0 Paper implies it is a dimer - automatic transfer from 1eqt 1u4n PROBNOT 1 1 NPS NPS 15381425 14617621 Paper says: the protein, a monomeric B-type carboxylesterase of about 34 kDa, was purified and characterized. - automatic transfer from 1qz3 1u4o NO 4 4 D2 D2 15978953 15117937 BU changed since last release and is now corrected - SP says tetramer - automatic transfer from 1t25 1u4s NO 4 4 D2 D2 15978953 15117937 BU changed since last release and is now corrected - SP says tetramer - automatic transfer from 1t25 1u59 PROBNOT 1 1 NPS NPS 15292186 15292186 Paper doent speak about an oligomer - PISA says monomer 1u5a NO 4 4 D2 D2 15978953 15117937 BU changed since last release and is now corrected - SP says tetramer - automatic transfer from 1t25 1u5c NO 4 4 D2 D2 15978953 15117937 BU changed since last release and is now corrected - SP says tetramer - automatic transfer from 1t25 1u5o PROBNOT 2 2 C2 C2 15522285 10543952 BU changed since last release and is now corrected - Paper says dimer - automaticaly inferred from 1qma 1u5t PROBNOT 4 4 NPS NPS 15329733 15329733 The paper describes this structure as being correct. 1u65 PROBYES 1 4 NPS NA 15772291 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 1u67 NO 2 2 C2 C2 15292194 15292194 -- Annotation transfered from 1cqe 1u6e NO 2 2 C2 C2 15713483 0 - automatic transfer from 1m1m 1u6q PROBNOT 1 1 NPS NPS 15582418 14711304 - automatic transfer from 1owd 1u6r NO 2 2 C2 C2 0 9849893 Paper says: CK plays an important role in the rapid regeneration of ATP in cells where such demands are high. It functions as an 85-kDa dimer - automatic transfer from 2crk 1u6s NO 2 2 C2 C2 15713483 0 - automatic transfer from 1m1m 1u72 PROBNOT 1 1 NPS NPS 15681865 15039552 - automatic transfer from 1s3u 1u73 NA 2 1 C2 NPS 15351695 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1umv 1u76 NO 3 3 C3 C3 15576034 8861913 - automatic transfer from 1axc 1u7b NO 3 3 C3 C3 15576034 8861913 - automatic transfer from 1axc 1u7r NO 1 1 NPS NPS 0 0 Myoglobin is a monomeric protein (8663546) - automatic transfer from 1a6m 1u7s NO 1 1 NPS NPS 0 0 Myoglobin is a monomeric protein (8663546) - automatic transfer from 1a6m 1u7t NA 4 4 D2 D2 15342248 15087549 BU changed since last release and is now corrected - I think it should be 4 subs, D2 sym, but PISA says D4 with 8 subs. A close rat homolog (>80%) has four subunits. Could be interesting to dig - automaticaly inferred from 1so8 1u83 YES 1 1 NPS NPS 0 0 Interface geometry conserved with 1qwg (42%) 1u8a PROBNOT 1 1 NPS NPS 15358538 12054870 SP says monomer - automatic transfer from 1l4u 1u8e NO 2 2 C2 C2 15175333 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. -- Annotation transfered from 1tkr 1u8g YES 2 1 C2 NPS 15502300 7664084 BU changed since last release and is now incorrect - SCOP error, only one domain is defined but there are two that are fused. - automaticaly inferred from 1hvc 1u94 NO 6 6 NS NS 15364575 15364575 In all three crystals, RecA is packed in a right-handed helical filament with a pitch of approximately 74 A. 1u98 NO 6 6 NS NS 15364575 0 In all three crystals, RecA is packed in a right-handed helical filament with a pitch of approximately 74 A. -- Annotation transfered from 1u94 1u99 NO 6 6 NS NS 15364575 0 In all three crystals, RecA is packed in a right-handed helical filament with a pitch of approximately 74 A. -- Annotation transfered from 1u94 1u9a PROBNOT 1 1 NPS NPS 9261152 9261152 Paper says: Like Arabidopsis thaliana Ubc1 and S. cerevisiae Ubc4, murine/human Ubc9 was crystallized as a monomer -- Annotation transfered from 1a3s 1u9b PROBNOT 1 1 NPS NPS 9261152 9261152 Paper says: Like Arabidopsis thaliana Ubc1 and S. cerevisiae Ubc4, murine/human Ubc9 was crystallized as a monomer -- Annotation transfered from 1a3s 1u9d PROBYES 2 1 NS NPS 0 0 No info - monomer most likely 1u9e_1 PROBYES 1 2 NPS C2 15548008 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1qkm 1u9e_2 PROBYES 1 2 NPS C2 15548008 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1qkm 1u9q NO 1 1 NPS NPS 15727867 1526455 The enzyme is a monomeric glycoprotein - automatic transfer from 1me4 1u9v NO 1 1 NPS NPS 15537340 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 1u9w NO 1 1 NPS NPS 15537340 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 1u9x NO 1 1 NPS NPS 15537340 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 1ua5 NO 2 2 C2 C2 0 0 -- Annotation transfered from 1bg5 1ua7 PROBNOT 1 1 NPS NPS 14617662 14617662 SP says monomer 1uaa PROBYES 2 2 NS C2 9288744 9288744 Paper says: we discuss below the possible forms of the functional Rep dimer. The Rep dimer seen in the asymmetric unit in the crystal has one molecule of dT(pT)15 shared between both Rep monomers (Figure 6A). However, we think it unlikely that this configuration reflects a functional form of the ssDNA-bound Rep dimer for several reasons. 1uae PROBYES 3 1 C3 NPS 8994972 8994972 MurA activity was shown to reside on a single monomeric polypeptide chain corresponding to the molecular mass predicted from the gene sequence. 1uaj NO 2 2 C2 C2 12773376 12773376 Interface geometry conserved with 1p9p (79% id) 1uak NO 2 2 C2 C2 12773376 12773376 Interface geometry conserved with 1p9p (79% id) -- Annotation transfered from 1uaj 1ual NO 2 2 C2 C2 12773376 12773376 Interface geometry conserved with 1p9p (79% id) -- Annotation transfered from 1uaj 1uam NO 2 2 C2 C2 12773376 12773376 Interface geometry conserved with 1p9p (79% id) -- Annotation transfered from 1uaj 1uas PROBNOT 1 1 NPS NPS 12657636 12657636 Paper says nothing - PISA says monomer 1uat PROBNOT 1 1 NPS NPS 14516747 14516747 -- Annotation transfered from 1cuo 1uay PROBNOT 4 4 D2 D2 0 0 PISA says tetramer, I think that too 1uaz PROBYES 2 1 C2 NPS -1 16540121 Apparently the trimer is not seen because of technical limitations. Paper says: But we have not yet succeeded in converting claret membrane into uniformly sized vesicles, which are requisite for growth of the P622 crystal 1ub0 NO 2 2 C2 C2 0 0 Interface geometry conserved with 1jxh (53%) 1ub3 NO 4 4 D2 D2 15388928 15388928 Paper says tetramer -- also unique arrangment? 1ubi PROBNOT 1 1 NPS NPS 8166633 8166633 Ubiquitin binds to proteins in different forms that may lead to the degradation of the target protein. For this reason I will consider all the ubiquitin structures to be correct. i.e. different forms may exist. -- Annotation transfered from 1ubq 1ubn NO 1 1 NPS NPS 10350485 10350485 -- Annotation transfered from 1yja 1ubp NO 9 9 C3 C3 -1 0 Interface geometry conserved with 1ejs (64% id avg) 1ubq PROBNOT 1 1 NPS NPS 3041007 3041007 Ubiquitin binds to proteins in different forms that may lead to the degradation of the target protein. For this reason I will consider all the ubiquitin structures to be correct. i.e. different forms may exist. 1ubs NO 4 4 C2 C2 8672457 8672457 Paper says a2b2 -- Annotation transfered from 2wsy 1ubv NO 2 2 C2 C2 8986756 8986756 Interface geometry conserved with 1rtr (27% id) -- Annotation transfered from 1uby 1ubw NO 2 2 C2 C2 8986756 8986756 Interface geometry conserved with 1rtr (27% id) -- Annotation transfered from 1uby 1ubx NO 2 2 C2 C2 8986756 8986756 Interface geometry conserved with 1rtr (27% id) -- Annotation transfered from 1uby 1uby NO 2 2 C2 C2 8986756 8986756 Interface geometry conserved with 1rtr (27% id) 1ubz NO 1 1 NPS NPS 12720276 12720276 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1uc0 NO 1 1 NPS NPS 12720276 12720276 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1uca PROBNOT 1 1 NPS NPS 10964705 10964705 No clear evidence was found. PISA says monomer 1ucc PROBNOT 1 1 NPS NPS 10964705 10964705 No clear evidence was found. PISA says monomer -- Annotation transfered from 1uca 1ucd PROBNOT 1 1 NPS NPS 0 0 No clear evidence was found. PISA says monomer -- Annotation transfered from 1uca 1ucf NO 2 2 C2 C2 12796482 12796482 1ucg_1 PROBNOT 1 1 NPS NPS 12731868 10964705 No clear evidence was found. PISA says monomer - automatic transfer from 1uca 1ucg_2 PROBNOT 1 1 NPS NPS 12731868 10964705 No clear evidence was found. PISA says monomer - automatic transfer from 1uca 1uci_1 PROBNOT 1 1 NPS NPS 12799387 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1uci_2 PROBNOT 1 1 NPS NPS 12799387 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1ucj_1 PROBNOT 1 1 NPS NPS 12799387 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1ucj_2 PROBNOT 1 1 NPS NPS 12799387 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1uck_1 PROBNOT 1 1 NPS NPS 12799387 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1uck_2 PROBNOT 1 1 NPS NPS 12799387 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1ucl_1 PROBNOT 1 1 NPS NPS 12799387 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1ucl_2 PROBNOT 1 1 NPS NPS 12799387 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 1ucn NO 6 6 D3 D3 12972261 12972261 Hexamer of two different chains: A and B (A6, A5B, A4B2, A3B3, A2B4, AB5, B6). - Interesting for Dmitry 1uco_1 NO 1 1 NPS NPS 15299565 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1uco_2 NO 1 1 NPS NPS 15299565 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1ucq NO 3 3 C3 C3 14672661 14672661 SP says trimer -- Annotation transfered from 2brd 1ucx NO 3 3 C3 C3 14705889 14705889 Paper says: In the cell, the constituent subunits are synthesized as a single polypeptide precursor, preproglycinin. The signal sequence is removed co-translationally in the endoplasmic reticulum (ER) and the resultant proglycinin assembles into trimers of about 8 S in size. As the proglycinin is sorted to protein storage vacuoles (PSV), a specific post-translational cleavage occurs between asparagine and glycine, resulting in a mature subunit consisting of the acidic and basic polypeptides. Finally, glycinin assembles into a hexamer of about 11 S. It has been demonstrated that the cleavage is a trigger for the formation of hexamers. - So the trimer exists and is an intermediate specie. -- very interesting case -- Annotation transfered from 1fxz 1ud1 NO 3 3 C3 C3 14705889 14705889 Paper says: In the cell, the constituent subunits are synthesized as a single polypeptide precursor, preproglycinin. The signal sequence is removed co-translationally in the endoplasmic reticulum (ER) and the resultant proglycinin assembles into trimers of about 8 S in size. As the proglycinin is sorted to protein storage vacuoles (PSV), a specific post-translational cleavage occurs between asparagine and glycine, resulting in a mature subunit consisting of the acidic and basic polypeptides. Finally, glycinin assembles into a hexamer of about 11 S. It has been demonstrated that the cleavage is a trigger for the formation of hexamers. - So the trimer exists and is an intermediate specie. -- very interesting case -- Annotation transfered from 1fxz 1ud2 PROBNOT 1 1 NPS NPS 12719434 12719434 Paper says nothing, related proteins are monomers and PISA says monomer 1ud3 PROBNOT 1 1 NPS NPS 12719434 12719434 Paper says nothing, related proteins are monomers and PISA says monomer -- Annotation transfered from 1ud2 1ud4 PROBNOT 1 1 NPS NPS 12719434 12719434 Paper says nothing, related proteins are monomers and PISA says monomer -- Annotation transfered from 1ud2 1ud5 PROBNOT 1 1 NPS NPS 12719434 12719434 Paper says nothing, related proteins are monomers and PISA says monomer -- Annotation transfered from 1ud2 1ud6 PROBNOT 1 1 NPS NPS 12719434 12719434 Paper says nothing, related proteins are monomers and PISA says monomer -- Annotation transfered from 1ud2 1ud8 PROBNOT 1 1 NPS NPS 12719434 12719434 Paper says nothing, related proteins are monomers and PISA says monomer -- Annotation transfered from 1ud2 1uda NO 2 2 C2 C2 9174344 9174344 SP says homodimer -- Annotation transfered from 2udp 1udb NO 2 2 C2 C2 9174344 9174344 SP says homodimer -- Annotation transfered from 2udp 1udc NO 2 2 C2 C2 9174344 9174344 SP says homodimer -- Annotation transfered from 2udp 1udn NO 6 6 D3 D3 12746447 12746447 Paper says hexamer 1udo NO 6 6 D3 D3 12746447 12746447 Paper says hexamer -- Annotation transfered from 1udn 1udq NO 6 6 D3 D3 12746447 12746447 Paper says hexamer -- Annotation transfered from 1udn 1udr YES 4 1 C2 NPS 11023787 2999789 CheY is a Mr 14,000 monomeric protein 1uds NO 6 6 D3 D3 12746447 12746447 Paper says hexamer -- Annotation transfered from 1udn 1udt PROBNOT 1 1 NPS NPS 12955149 12955149 No info about oligomer in all papers, PISa says monomer and inspection of the structure let think it is right. -- Annotation transfered from 1uho 1udu PROBYES 2 1 C2 NPS 12955149 12955149 No info about oligomer in all papers, PISa says monomer and inspection of the structure let think it is right. 1udv NO 2 2 C2 C2 12837780 12837780 Dimer similar to 1h0x even though sequence similarity is about 30% 1ue1 YES 4 4 D2 D2 12888346 12888346 Reconstruction is wrong 1ue5 NO 4 4 D2 D2 12888346 12888346 Paper says it is a tetramer 1ue6_1 YES 4 4 D2 D2 12888346 12888346 Reconstruction is wrong - automatic transfer from 1ue1 1ue6_2 YES 4 4 D2 D2 12888346 12888346 Reconstruction is wrong - automatic transfer from 1ue1 1ue7_1 YES 4 4 D2 D2 12888346 12888346 Reconstruction is wrong - automatic transfer from 1ue1 1ue7_2 YES 4 4 D2 D2 12888346 12888346 Reconstruction is wrong - automatic transfer from 1ue1 1uec YES 1 2 NPS C2 15147273 15147273 Should be a domain swapped dimer 1uef NA 2 1 NS NPS 14607833 14607833 Oligomeric state not mentioned --> Probably monomner but PISA doesnt agree. -- Annotation transfered from 1p5t 1ueg PROBNOT 1 1 NPS NPS 12857735 12857735 1uek PROBNOT 1 1 NPS NPS 12771135 12771135 Paper says: The crystallographic model of T. thermophilus HB8 CMK shows no evidence of self-association of the protein. 1uer_1 PROBNOT 2 2 C2 C2 12962504 10848964 BU changed since last release and is now corrected - Paper says dimer: Each pair of subunits forms a compact dimer, but not a tetramer. - automaticaly inferred from 1qnn 1uer_2 PROBNOT 2 2 C2 C2 12962504 10848964 BU changed since last release and is now corrected - Paper says dimer: Each pair of subunits forms a compact dimer, but not a tetramer. - automaticaly inferred from 1qnn 1ues_1 PROBNOT 2 2 C2 C2 12962504 10848964 BU changed since last release and is now corrected - Paper says dimer: Each pair of subunits forms a compact dimer, but not a tetramer. - automaticaly inferred from 1qnn 1ues_2 PROBNOT 2 2 C2 C2 12962504 10848964 BU changed since last release and is now corrected - Paper says dimer: Each pair of subunits forms a compact dimer, but not a tetramer. - automaticaly inferred from 1qnn 1uet YES 1 2 NPS C2 14592988 14592988 -- Annotation transfered from 1ueu 1ueu YES 1 2 NPS C2 14592988 14592988 1uev YES 1 2 NPS C2 14592988 14592988 -- Annotation transfered from 1ueu 1uf4 NA 4 4 D2 D2 0 0 Paper says: From biochemical characterization studies of DCase it has been reported that DCase forms a dimer or a trimer. In the crystal structure, DCase exists as an associated homotetramer -- Annotation transfered from 1erz 1uf5 NA 4 4 D2 D2 0 0 Paper says: From biochemical characterization studies of DCase it has been reported that DCase forms a dimer or a trimer. In the crystal structure, DCase exists as an associated homotetramer -- Annotation transfered from 1erz 1uf7 NA 4 4 D2 D2 0 0 Paper says: From biochemical characterization studies of DCase it has been reported that DCase forms a dimer or a trimer. In the crystal structure, DCase exists as an associated homotetramer -- Annotation transfered from 1erz 1uf8 NA 4 4 D2 D2 0 0 Paper says: From biochemical characterization studies of DCase it has been reported that DCase forms a dimer or a trimer. In the crystal structure, DCase exists as an associated homotetramer -- Annotation transfered from 1erz 1ufh PROBYES 4 2 C2 C2 14635137 14635137 Paper says: The gel filtration experiment indicated the oligomeric form to be a dimer (data not shown). A structural homologue of YYCN, yeast Hpa2, has been shown to be present as a dimer in solution but forms a stable tetramer in the presence of its cofactor, acetyl CoA. 1ufj NO 1 1 NPS NPS 15106972 15106972 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1ufk YES 1 2 NPS C2 0 0 No paper, but looking at the dimer it is certainly the right assembly (PISA) 1ufl NO 3 3 C3 C3 15629661 0 Interface geometry conserved with 1pil (44%) 1ufp NO 1 1 NPS NPS 15106972 15106972 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1ug6 NA 1 1 NPS NPS 0 0 No paper 1uga PROBNOT 1 1 NPS NPS 8987974 8987974 9000633 says monomeric 1ugb PROBNOT 1 1 NPS NPS 8987974 8987974 9000633 says monomeric -- Annotation transfered from 1uga 1ugc PROBNOT 1 1 NPS NPS 8987974 8987974 9000633 says monomeric -- Annotation transfered from 1uga 1ugd PROBNOT 1 1 NPS NPS 8987974 8987974 9000633 says monomeric -- Annotation transfered from 1uga 1uge PROBNOT 1 1 NPS NPS 8987974 8987974 9000633 says monomeric -- Annotation transfered from 1uga 1ugf PROBNOT 1 1 NPS NPS 8987974 8987974 9000633 says monomeric -- Annotation transfered from 1uga 1ugg PROBNOT 1 1 NPS NPS 8987974 8987974 9000633 says monomeric -- Annotation transfered from 1uga 1ugu PROBNOT 1 1 NPS NPS 15583378 15583378 SP says monomer -- Annotation transfered from 1s1z 1uh5 NO 4 4 D2 D2 15381426 0 -- Annotation transfered from 1v35 1uhn PROBNOT 1 1 NPS NPS 12871972 12871972 Paper does not mention a dimer - PISA says monomer 1uho PROBNOT 1 1 NPS NPS 12955149 12955149 No info about oligomer in all papers, PISa says monomer and inspection of the structure let think it is right. 1ui7 NO 2 2 C2 C2 14979714 14979714 Interface geometry conserved with 1ksi (25%) -- Annotation transfered from 1sii 1ui8 NO 2 2 C2 C2 14979714 14979714 Interface geometry conserved with 1ksi (25%) -- Annotation transfered from 1sii 1uia NO 1 1 NPS NPS 11983077 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1uib NO 1 1 NPS NPS 11983077 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1uic NO 1 1 NPS NPS 9348077 9348077 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1uid NO 1 1 NPS NPS 9348077 9348077 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1uie NO 1 1 NPS NPS 9348077 9348077 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1uif NO 1 1 NPS NPS 9348077 9348077 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1uig NO 1 1 NPS NPS 9348077 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1uih NO 1 1 NPS NPS 11983077 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1uir NO 4 4 D2 D2 0 0 Interface geometry conserved with 1iy9 (34%) 1uis YES 2 2 C2 D2 12909624 12909624 Paper says tetrameric 1uiy PROBNOT 6 6 D3 D3 0 0 1uj0 PROBNOT 1 1 NPS NPS 13129930 13129930 Paper mention a gel filtration and no dimer. PISA says monomer 1uj4 YES 1 2 NPS C2 13679361 13679361 Interface geometry conserved with 1lkz (40%) -- Annotation transfered from 1uj6 1uj5 YES 1 2 NPS C2 13679361 13679361 Interface geometry conserved with 1lkz (40%) -- Annotation transfered from 1uj6 1uj6 YES 1 2 NPS C2 13679361 13679361 Interface geometry conserved with 1lkz (40%) 1ujn NO 2 2 C2 C2 15508124 0 Interface geometry conserved with 1nua (38%) 1ujp NA 1 1 NPS NPS 16272128 0 No paper, PISA says monomer but related proteins are dimeric 1ujq NO 4 4 D2 D2 14575713 14575713 Interface geometry conseved with 1s2u (30%) 1uk6 NO 2 2 C2 C2 15784976 15784976 The ß8 strands of both of the subunits form an antiparallel ß-sheet, and this tight interaction seems to be responsible for the dimeric structure of CumD in solution (Saku et al. 2002) -- Annotation transfered from 1iup 1uk7 NO 2 2 C2 C2 15784976 15784976 The ß8 strands of both of the subunits form an antiparallel ß-sheet, and this tight interaction seems to be responsible for the dimeric structure of CumD in solution (Saku et al. 2002) -- Annotation transfered from 1iup 1uk8 NO 2 2 C2 C2 15784976 15784976 The ß8 strands of both of the subunits form an antiparallel ß-sheet, and this tight interaction seems to be responsible for the dimeric structure of CumD in solution (Saku et al. 2002) -- Annotation transfered from 1iup 1uk9 NO 2 2 C2 C2 15784976 15784976 The ß8 strands of both of the subunits form an antiparallel ß-sheet, and this tight interaction seems to be responsible for the dimeric structure of CumD in solution (Saku et al. 2002) -- Annotation transfered from 1iup 1uka NO 2 2 C2 C2 15784976 15784976 The ß8 strands of both of the subunits form an antiparallel ß-sheet, and this tight interaction seems to be responsible for the dimeric structure of CumD in solution (Saku et al. 2002) -- Annotation transfered from 1iup 1ukb NO 2 2 C2 C2 15784976 15784976 The ß8 strands of both of the subunits form an antiparallel ß-sheet, and this tight interaction seems to be responsible for the dimeric structure of CumD in solution (Saku et al. 2002) -- Annotation transfered from 1iup 1ukg NO 2 2 C2 C2 14729339 14729339 Implied in paper that it is a dimer, PISA also says that -- Annotation transfered from 1n3q 1ukh PROBNOT 1 1 NPS NPS 15141161 15141161 -- Annotation transfered from 1uki 1uki PROBNOT 1 1 NPS NPS 15141161 15141161 1ukj NO 4 4 D2 D2 0 10965031 Paper says tetramer - but says that dimer is active - interesting example for saying that dimer is functional intermediate - automatic transfer from 1gc0 1uko_1 PROBNOT 1 1 NPS NPS 14631070 15178253 SP says monomer - automatic transfer from 1v3i 1uko_2 PROBNOT 1 1 NPS NPS 14631070 15178253 SP says monomer - automatic transfer from 1v3i 1uko_3 PROBNOT 1 1 NPS NPS 14631070 15178253 SP says monomer - automatic transfer from 1v3i 1uko_4 PROBNOT 1 1 NPS NPS 14631070 15178253 SP says monomer - automatic transfer from 1v3i 1ukp_1 PROBNOT 1 1 NPS NPS 14631070 15178253 SP says monomer - automatic transfer from 1v3i 1ukp_2 PROBNOT 1 1 NPS NPS 14631070 15178253 SP says monomer - automatic transfer from 1v3i 1ukp_3 PROBNOT 1 1 NPS NPS 14631070 15178253 SP says monomer - automatic transfer from 1v3i 1ukp_4 PROBNOT 1 1 NPS NPS 14631070 15178253 SP says monomer - automatic transfer from 1v3i 1uku PROBNOT 3 3 C3 C3 14706845 0 1ul9 NO 4 4 D2 D2 15062091 15062091 Paper says: Kinetic studies on wild-type and mutant CGL2 proteins demonstrate that the tetrameric organization is essential for functionality. -- Annotation transfered from 1ulg 1ula NO 3 3 C3 C3 1763067 1763067 Paper says trimer 1ulb NO 3 3 C3 C3 1763067 1763067 Paper says trimer -- Annotation transfered from 1ula 1ulc NO 4 4 D2 D2 15062091 15062091 Paper says: Kinetic studies on wild-type and mutant CGL2 proteins demonstrate that the tetrameric organization is essential for functionality. -- Annotation transfered from 1ulg 1uld_1 NO 4 4 D2 D2 15062091 15062091 Paper says: Kinetic studies on wild-type and mutant CGL2 proteins demonstrate that the tetrameric organization is essential for functionality. - automatic transfer from 1ulg 1uld_2 NO 4 4 D2 D2 15062091 15062091 Paper says: Kinetic studies on wild-type and mutant CGL2 proteins demonstrate that the tetrameric organization is essential for functionality. - automatic transfer from 1ulg 1ule NO 4 4 D2 D2 15062091 15062091 Paper says: Kinetic studies on wild-type and mutant CGL2 proteins demonstrate that the tetrameric organization is essential for functionality. -- Annotation transfered from 1ulg 1ulf NO 4 4 D2 D2 15062091 15062091 Paper says: Kinetic studies on wild-type and mutant CGL2 proteins demonstrate that the tetrameric organization is essential for functionality. -- Annotation transfered from 1ulg 1ulg NO 4 4 D2 D2 15062091 15062091 Paper says: Kinetic studies on wild-type and mutant CGL2 proteins demonstrate that the tetrameric organization is essential for functionality. 1uli NO 6 6 C3 C3 15342255 15342255 Interface geometry conserved with 1ndo (28%) -- Annotation transfered from 1ulj 1ulj NO 6 6 C3 C3 15342255 15342255 Interface geometry conserved with 1ndo (28%) 1ult PROBNOT 2 2 C2 C2 15145952 15145952 Paper says dimer - domain swapped -- interesting: Yeast s one is a trimer --> same function and different QS (That s rare!!) - also interesting: a homologous prot from B. subtilis works in a non ribosomal peptide synthase (ribosome ansector?) 1ulw PROBNOT 1 1 NPS NPS 15313618 10671516 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer - automatic transfer from 1cmj 1um2_1 PROBNOT 1 1 NPS NPS 14646148 10601013 BU changed since last release and is now corrected - From the paper it seems to be a monomer. - automaticaly inferred from 1ef0 1um2_2 PROBNOT 1 1 NPS NPS 14646148 10601013 BU changed since last release and is now corrected - From the paper it seems to be a monomer. - automaticaly inferred from 1ef0 1um8 NA 1 6 NPS C6 14514695 14514695 Paper says hexamer -- PISA does not find it 1umj_1 PROBNOT 3 3 C3 C3 15351719 0 - automatic transfer from 1uku 1umj_2 PROBNOT 3 3 C3 C3 15351719 0 - automatic transfer from 1uku 1umn NO 12 12 Tetr Tetr 15081812 0 Interface geometry conserved with 1o9r (30%) 1umo NO 2 2 C2 C2 15095869 15165856 dimeric CYGB species observed in gel-filtration and in dynamic light-scattering experiments 1ump_1 PROBYES 2 1 NS NPS 15113001 9295270 BU changed since last release and is now incorrect - Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer - automaticaly inferred from 1sqc 1ump_2 PROBYES 2 1 NS NPS 15113001 9295270 BU changed since last release and is now incorrect - Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer - automaticaly inferred from 1sqc 1ump_3 PROBYES 2 1 C2 NPS 15113001 9295270 BU changed since last release and is now incorrect - Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer - automaticaly inferred from 1sqc 1umv NA 1 1 NPS NPS 0 0 1un0_1 NO 1 1 NPS NPS 14532109 10745017 Paper says: To prevent the dimerization of Kapα50 we engineered a point mutation (Tyr→Asp at position 397, Y397D). -- Interesting case of dimer interference by one point mutation. -- Annotation transfered from 1ee5 1un0_2 NO 1 1 NPS NPS 14532109 10745017 Paper says: To prevent the dimerization of Kapα50 we engineered a point mutation (Tyr→Asp at position 397, Y397D). -- Interesting case of dimer interference by one point mutation. -- Annotation transfered from 1ee5 1un2 NO 1 1 NPS NPS 14747707 0 It seems that it is accepted that the native form of the protein is a monomer. -- Annotation transfered from 1a2j 1un3 NO 1 1 NPS NPS 14756559 0 Human angiogenin is monomeric -- Annotation transfered from 1h52 1un4 NO 1 1 NPS NPS 14756559 0 Human angiogenin is monomeric -- Annotation transfered from 1h52 1un5 NO 1 1 NPS NPS 14756559 0 Human angiogenin is monomeric -- Annotation transfered from 1h52 1una PROBNOT 2 2 C2 C2 8976557 8976557 Two fold axis of the virus shell 1unb PROBYES 1 3 NPS C3 14718929 0 BU changed since last release and is now incorrect - this suggests that the trimeric structure of the apoenzyme found in the crystal might have some functional significance, for example in the protection of the C-terminal arm (rich in lysines and arginines) against proteases in the apo- or resting forms of DAOCS. However, DAOCS dissociates into monomers in the presence of Fe(II) and 2-oxoglutarate. -- Annotation transfered from 1uog 1une PROBNOT 1 1 NPS NPS 10089393 10089393 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1o2e 1unk NO 4 1 NS NS 9135159 9639578 we found that Im7 only ever exists in solution as a monomer, even up to protein concentrations of 15 mg/ml 1uns PROBNOT 1 1 NPS NPS 14559915 0 dimer not mentioned in literature, PISA says monomer -- Annotation transfered from 1i4p 1uo2 NO 4 4 C4 C4 16008357 8248779 Paper says tetramer - automatic transfer from 1gcl 1uo9 PROBNOT 3 3 C3 C3 14718929 0 this suggests that the trimeric structure of the apoenzyme found in the crystal might have some functional significance, for example in the protection of the C-terminal arm (rich in lysines and arginines) against proteases in the apo- or resting forms of DAOCS. However, DAOCS dissociates into monomers in the presence of Fe(II) and 2-oxoglutarate. -- Annotation transfered from 1uog 1uob PROBNOT 3 3 C3 C3 14718929 0 this suggests that the trimeric structure of the apoenzyme found in the crystal might have some functional significance, for example in the protection of the C-terminal arm (rich in lysines and arginines) against proteases in the apo- or resting forms of DAOCS. However, DAOCS dissociates into monomers in the presence of Fe(II) and 2-oxoglutarate. -- Annotation transfered from 1uog 1uof PROBNOT 3 3 C3 C3 14718929 0 this suggests that the trimeric structure of the apoenzyme found in the crystal might have some functional significance, for example in the protection of the C-terminal arm (rich in lysines and arginines) against proteases in the apo- or resting forms of DAOCS. However, DAOCS dissociates into monomers in the presence of Fe(II) and 2-oxoglutarate. -- Annotation transfered from 1uog 1uog PROBNOT 3 3 C3 C3 14718929 9723623 this suggests that the trimeric structure of the apoenzyme found in the crystal might have some functional significance, for example in the protection of the C-terminal arm (rich in lysines and arginines) against proteases in the apo- or resting forms of DAOCS. However, DAOCS dissociates into monomers in the presence of Fe(II) and 2-oxoglutarate. 1uok PROBNOT 1 1 NPS NPS 9193006 9193006 Paper says nothing, PISA says monomer 1uol_1 NA 1 4 NPS C2 14534297 8023157 BU changed since last release and is now incorrect - I am not sure about that one. 9628871 shows a cartoon of how it bind. Normally, there are 2 palindromic sequences, but in the crystal structure there are only 3 proteins, and the binding mode seems not compatible with that shown in 9628871 - automaticaly inferred from 1tsr 1uol_2 NA 1 4 NPS C2 14534297 8023157 BU changed since last release and is now incorrect - I am not sure about that one. 9628871 shows a cartoon of how it bind. Normally, there are 2 palindromic sequences, but in the crystal structure there are only 3 proteins, and the binding mode seems not compatible with that shown in 9628871 - automaticaly inferred from 1tsr 1uom YES 1 2 NPS C2 12825935 0 Should be a dimer identical to the other ones (PISA is right) 1uot PROBNOT 1 1 NPS NPS 12499389 12499389 From the figures in the paper I understand that it is monomeric - PISA says monomeric too. 1uov PROBNOT 1 1 NPS NPS 15340165 0 paper do not speak about any olig. state, PISA says monomer. -- Annotation transfered from 1tjm 1uow PROBNOT 1 1 NPS NPS 15340165 0 paper do not speak about any olig. state, PISA says monomer. -- Annotation transfered from 1tjm 1up5_1 PROBNOT 1 1 NPS NPS 15299715 3145979 - automatic transfer from 3cln 1up5_2 PROBNOT 1 1 NPS NPS 15299715 3145979 - automatic transfer from 3cln 1up8 NO 12 12 Tetr Tetr 0 0 Interface geometry conserved with 1qhb (91%) 1up9 NO 1 1 NPS NPS 14705030 11551953 Paper says: Tetraheme cytochrome c(3) is a small soluble and monomeric protein that performs a central step in the bioenergetic metabolism of sulfate reducing bacteria - PISA says monomer too - automatic transfer from 1gm4 1upa NO 4 4 D2 D2 14623876 0 Interface geometry conserved with 1ovm (22%) -- Annotation transfered from 1upb 1upb NO 4 4 D2 D2 14623876 0 Interface geometry conserved with 1ovm (22%) 1upc PROBYES 6 4 NS D2 14623876 0 BU changed since last release and is now incorrect - Interface geometry conserved with 1ovm (22%) - automaticaly inferred from 1upb 1upd NO 1 1 NPS NPS 14705030 11551953 Paper says: Tetraheme cytochrome c(3) is a small soluble and monomeric protein that performs a central step in the bioenergetic metabolism of sulfate reducing bacteria - PISA says monomer too - automatic transfer from 1gm4 1upf NO 4 4 D2 D2 9628859 9628859 Interface geometry conserved with 1o5o (40%) -- Annotation transfered from 1jlr 1upi NO 2 2 C2 C2 15103135 0 Interface geometry conserved with 1rtv (40%) -- Annotation transfered from 1pm7 1upj NO 2 2 C2 C2 7658450 7658450 -- Annotation transfered from 1ajx 1upu NO 4 4 D2 D2 9628859 9628859 Interface geometry conserved with 1o5o (40%) -- Annotation transfered from 1jlr 1uq4 NO 2 2 C2 C2 14686928 0 Blocked ricin undergoes a pH-dependent reversible self-association, being predominantly dimeric at neutral pH and monomeric at acidic pH. -- Annotation transfered from 1uq5 1uq5 NO 2 2 C2 C2 14686928 9147041 Blocked ricin undergoes a pH-dependent reversible self-association, being predominantly dimeric at neutral pH and monomeric at acidic pH. 1uqr NO 12 12 Tetr Tetr 14993670 0 Interface geometry conserved with 1h0s (48%) 1uqt NO 2 2 C2 C2 14570926 12498887 Dimer tetramer equilibrium - Light scattering data show that overexpressed His-tagged OtsA exists as both dimers and tetramers in equilibrium. It is not clear if this has any biological significance, perhaps reflecting the ability of a dimer to interact with the phosphatase OtsB (although in E. coli, OtsA most likely exists as a discrete entity; in some other organisms, such as Saccharomyces cerevisae, OtsA and OtsB are associated into a multicomponent complex [30]) or are merely an overexpression artifact. 1ur3 PROBYES 1 3 NPS C3 0 0 BU changed since last release and is now incorrect - Given the burried ASA I hardly believe the trimer could be an artifact -- Annotation transfered from 1og6 1ur5 YES 2 4 C2 D2 14636605 0 BU changed since last release and is now incorrect - Paper says tetramer -- very interesting paper: mutation introduced to increase the stability, 1 mutation increases the Tm by 24 degrees! Good support to state that it is impossible to measure structural factors responsible for a difference between mesophiles and thermophiles proteins -- Annotation transfered from 1uxg 1uri_1 NA 1 1 NPS NPS 8383207 0 BU changed since last release and is now corrected - No clear info found - automaticaly inferred from 1azc 1uri_2 NA 1 1 NPS NPS 8383207 0 BU changed since last release and is now corrected - No clear info found - automaticaly inferred from 1azc 1url PROBNOT 1 1 NPS NPS 15488769 9660955 Paper doesnt mention a dimer and PISA says monomer - automatic transfer from 1qfp 1urm YES 1 2 NPS C2 -1 11518528 BU changed since last release and is now incorrect - Interface geometry conserved with 1psq (30%) - automatic transfer from 1h4o_2 1uro NO 2 2 C2 C2 9564029 9564029 Interface geometry conserved with 1j93 (35%) 1urp_1 NO 1 1 NPS NPS 9641984 7982928 ribose ABC transporter, subunit B - monomer according to EcoCyc - automatic transfer from 1drj 1urp_2 NO 1 1 NPS NPS 9641984 7982928 ribose ABC transporter, subunit B - monomer according to EcoCyc - automatic transfer from 1drj 1urp_3 NO 1 1 NPS NPS 9641984 7982928 ribose ABC transporter, subunit B - monomer according to EcoCyc - automatic transfer from 1drj 1urp_4 NO 1 1 NPS NPS 9641984 7982928 ribose ABC transporter, subunit B - monomer according to EcoCyc - automatic transfer from 1drj 1urt PROBNOT 1 1 NPS NPS 8794740 8794740 10529183 says monomer 1urv_1 PROBYES 1 2 NPS C2 0 15165856 BU changed since last release and is now incorrect - disulfide bonded dimer - automaticaly inferred from 1v5h 1urv_2 PROBYES 1 2 NPS C2 0 15165856 BU changed since last release and is now incorrect - disulfide bonded dimer - automaticaly inferred from 1v5h 1urw NO 1 1 NPS NPS 15081018 0 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1ury_1 PROBYES 1 2 NPS C2 0 15165856 BU changed since last release and is now incorrect - disulfide bonded dimer - automaticaly inferred from 1v5h 1ury_2 PROBYES 1 2 NPS C2 0 15165856 BU changed since last release and is now incorrect - disulfide bonded dimer - automaticaly inferred from 1v5h 1urz_1 YES 3 2 C3 C2 14963486 7753193 BU changed since last release and is now incorrect - Interface geometry conserved with 1oan (38%) - automaticaly inferred from 1svb 1urz_2 YES 3 2 C3 C2 14963486 7753193 BU changed since last release and is now incorrect - Interface geometry conserved with 1oan (38%) - automaticaly inferred from 1svb 1us0 NO 1 1 NPS NPS 15146478 0 SwissProt and PISA say monomer -- Annotation transfered from 1ads 1usb NO 2 2 C2 C2 15333749 0 glutathione S-transferases are functional dimers. -- Annotation transfered from 1pkw 1usg PROBNOT 1 1 NPS NPS 14672931 14672931 BU changed since last release and is now corrected - No dimer mentioned in the paper - EcoCyc shows that it is part of a larger complex and that it contributes one protein only. 1usi PROBYES 2 1 C2 NPS 14672931 14672931 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - No dimer mentioned in the paper - EcoCyc shows that it is part of a larger complex and that it contributes one protein only. - automaticaly inferred from 1usg 1usk PROBYES 4 1 NS NPS 14672931 14672931 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - No dimer mentioned in the paper - EcoCyc shows that it is part of a larger complex and that it contributes one protein only. - automaticaly inferred from 1usg 1usn PROBNOT 1 1 NPS NPS 9792098 9792098 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme -- Annotation transfered from 1caq 1usq_1 PROBYES 4 3 NS C3 15331605 15331605 BU changed since last release and is now incorrect - Briefly, the adhesins were purified from the supernatant using nickel affinity chromatography followed by size exclusion chromatography in an S75-Sepharose column (Amersham Biosciences) to separate the trimeric forms from small amounts of monomeric, dimeric, and aggregated forms of the adhesins - automaticaly inferred from 1ut1 1usq_2 PROBNOT 3 3 C3 C3 15331605 15331605 BU changed since last release and is now corrected - Briefly, the adhesins were purified from the supernatant using nickel affinity chromatography followed by size exclusion chromatography in an S75-Sepharose column (Amersham Biosciences) to separate the trimeric forms from small amounts of monomeric, dimeric, and aggregated forms of the adhesins - automaticaly inferred from 1ut1 1usq_3 PROBNOT 3 3 C3 C3 15331605 15331605 BU changed since last release and is now corrected - Briefly, the adhesins were purified from the supernatant using nickel affinity chromatography followed by size exclusion chromatography in an S75-Sepharose column (Amersham Biosciences) to separate the trimeric forms from small amounts of monomeric, dimeric, and aggregated forms of the adhesins - automaticaly inferred from 1ut1 1usq_4 PROBNOT 3 3 C3 C3 15331605 15331605 BU changed since last release and is now corrected - Briefly, the adhesins were purified from the supernatant using nickel affinity chromatography followed by size exclusion chromatography in an S75-Sepharose column (Amersham Biosciences) to separate the trimeric forms from small amounts of monomeric, dimeric, and aggregated forms of the adhesins - automaticaly inferred from 1ut1 1usq_5 PROBNOT 3 3 C3 C3 15331605 15331605 BU changed since last release and is now corrected - Briefly, the adhesins were purified from the supernatant using nickel affinity chromatography followed by size exclusion chromatography in an S75-Sepharose column (Amersham Biosciences) to separate the trimeric forms from small amounts of monomeric, dimeric, and aggregated forms of the adhesins - automaticaly inferred from 1ut1 1usq_6 PROBNOT 3 3 C3 C3 15331605 15331605 BU changed since last release and is now corrected - Briefly, the adhesins were purified from the supernatant using nickel affinity chromatography followed by size exclusion chromatography in an S75-Sepharose column (Amersham Biosciences) to separate the trimeric forms from small amounts of monomeric, dimeric, and aggregated forms of the adhesins - automaticaly inferred from 1ut1 1usz PROBNOT 3 3 C3 C3 15331605 15331605 Briefly, the adhesins were purified from the supernatant using nickel affinity chromatography followed by size exclusion chromatography in an S75-Sepharose column (Amersham Biosciences) to separate the trimeric forms from small amounts of monomeric, dimeric, and aggregated forms of the adhesins 1ut0_1 PROBYES 1 2 NPS C2 15095869 15165856 BU changed since last release and is now incorrect - disulfide bonded dimer - automaticaly inferred from 1v5h 1ut0_2 PROBYES 1 2 NPS C2 15095869 15165856 BU changed since last release and is now incorrect - disulfide bonded dimer - automaticaly inferred from 1v5h 1ut1 PROBYES 6 3 D3 C3 15331605 15331605 Briefly, the adhesins were purified from the supernatant using nickel affinity chromatography followed by size exclusion chromatography in an S75-Sepharose column (Amersham Biosciences) to separate the trimeric forms from small amounts of monomeric, dimeric, and aggregated forms of the adhesins 1ut2_1 PROBNOT 3 3 C3 C3 15331605 15331605 Briefly, the adhesins were purified from the supernatant using nickel affinity chromatography followed by size exclusion chromatography in an S75-Sepharose column (Amersham Biosciences) to separate the trimeric forms from small amounts of monomeric, dimeric, and aggregated forms of the adhesins - automatic transfer from 1usz 1ut2_2 PROBNOT 3 3 C3 C3 15331605 15331605 Briefly, the adhesins were purified from the supernatant using nickel affinity chromatography followed by size exclusion chromatography in an S75-Sepharose column (Amersham Biosciences) to separate the trimeric forms from small amounts of monomeric, dimeric, and aggregated forms of the adhesins - automatic transfer from 1usz 1ut2_3 PROBNOT 3 3 C3 C3 15331605 15331605 Briefly, the adhesins were purified from the supernatant using nickel affinity chromatography followed by size exclusion chromatography in an S75-Sepharose column (Amersham Biosciences) to separate the trimeric forms from small amounts of monomeric, dimeric, and aggregated forms of the adhesins - automatic transfer from 1usz 1ut6 PROBYES 1 4 NPS NA 16942022 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 1utc PROBYES 2 1 C2 NPS 14981508 10655490 BU changed since last release and is now incorrect - Paper says: The fractions containing the terminal domain were collected, concentrated, and loaded on a Superdex 75 column for size-exclusion chromatography in buffer A. The td40 eluted as a monomeric species - automaticaly inferred from 1c9i 1uti PROBNOT 1 1 NPS NPS 15100220 0 1utj PROBNOT 1 1 NPS NPS 15044735 0 -- Annotation transfered from 1utm 1utk PROBNOT 1 1 NPS NPS 15044735 0 -- Annotation transfered from 1utm 1utl PROBNOT 1 1 NPS NPS 15044735 0 -- Annotation transfered from 1utm 1utm PROBNOT 1 1 NPS NPS 15044735 0 1utn PROBNOT 1 1 NPS NPS 15044735 0 -- Annotation transfered from 1az8 1uto PROBNOT 1 1 NPS NPS 15044735 0 -- Annotation transfered from 1az8 1utp PROBNOT 1 1 NPS NPS 15044735 0 -- Annotation transfered from 1az8 1utq PROBNOT 1 1 NPS NPS 15044735 0 -- Annotation transfered from 1az8 1uu0_1 NO 2 2 C2 C2 15007066 0 - automatic transfer from 1uu2 1uu0_2 NO 2 2 C2 C2 15007066 0 - automatic transfer from 1uu2 1uu1_1 NO 2 2 C2 C2 15007066 0 - automatic transfer from 1uu2 1uu1_2 NO 2 2 C2 C2 15007066 0 - automatic transfer from 1uu2 1uu2 NO 2 2 C2 C2 15007066 0 1uu3 NO 1 1 NPS NPS 14962382 0 gel filtration studies suggest that PDK1 is monomeric -- Annotation transfered from 1okz 1uu4 PROBNOT 1 1 NPS NPS 15364577 0 Paper says nothing, PISA says monomer 1uu5 PROBNOT 1 1 NPS NPS 15364577 0 Paper says nothing, PISA says monomer -- Annotation transfered from 1uu4 1uu6 PROBNOT 1 1 NPS NPS 15364577 0 Paper says nothing, PISA says monomer -- Annotation transfered from 1uu4 1uu7 NO 1 1 NPS NPS 14962382 0 gel filtration studies suggest that PDK1 is monomeric -- Annotation transfered from 1okz 1uu8 NO 1 1 NPS NPS 14962382 0 gel filtration studies suggest that PDK1 is monomeric -- Annotation transfered from 1okz 1uu9 NO 1 1 NPS NPS 14962382 0 gel filtration studies suggest that PDK1 is monomeric -- Annotation transfered from 1okz 1uue PROBNOT 1 1 NPS NPS 14978284 0 -- Annotation transfered from 1neg 1uuf YES 1 2 NPS C2 0 0 BU changed since last release and is now incorrect - Interface geometry conserved with 1qor (22%) 1uuj YES 4 2 NS C2 15274919 15274919 Paper says: We ruled out the possibility that the homodimer dissociates into native monomers before unfolding, since in such a case the unfolding reaction would be unimolecular and protein concentration independent. Since the midpoint of the unfolding transition ([GdmCl]1/2) clearly depends on the protein concentration, the dimer is thermodynamically favored at higher protein concentrations 1uup_1 PROBYES 2 4 C2 D2 15295110 9878045 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Tetramer might be relevant: Structural and mutational studies of SEB, SEC, SPEA, and TSST1 suggest MHC binding uses the sur face on the front of Domain 1.Since this sur face is blocked in the SPEA tetramer, tetramer–monomer equilibrium will likely modulate superantigenicity. The ability of factors to stabilize the tetramer could be employed to reduce the ability of SPEA to stimulate T-cell proliferation. - automaticaly inferred from 1ha5_3 1uup_2 PROBYES 2 4 C2 D2 15295110 9878045 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Tetramer might be relevant: Structural and mutational studies of SEB, SEC, SPEA, and TSST1 suggest MHC binding uses the sur face on the front of Domain 1.Since this sur face is blocked in the SPEA tetramer, tetramer–monomer equilibrium will likely modulate superantigenicity. The ability of factors to stabilize the tetramer could be employed to reduce the ability of SPEA to stimulate T-cell proliferation. - automaticaly inferred from 1ha5_3 1uux NO 3 3 C3 C3 15306815 0 Interface geometry conserved with 1jlj (52%) 1uuy NO 3 3 C3 C3 15306815 0 Interface geometry conserved with 1jlj (52%) -- Annotation transfered from 1uux 1uv0 PROBNOT 1 1 NPS NPS 0 10417404 Paper says: The NaCl was required to avoid protein aggregation and to keep the protein as a monomer. 1uv5 YES 1 2 NPS C2 14700633 0 BU changed since last release and is now incorrect - Paper says dimer detected in solution but the functional significance is unclear (autoinhibition is a possibility) - monomer/dimer equilibrium -- Annotation transfered from 1h8f 1uva NA 2 1 C2 NPS 15295114 9512714 Paper does not mention a dimer but PISA says dimer - automatic transfer from 1rzl 1uvb NA 2 1 C2 NPS 15295114 9512714 Paper does not mention a dimer but PISA says dimer - automatic transfer from 1rzl 1uvc NA 2 1 C2 NPS 15295114 9512714 Paper does not mention a dimer but PISA says dimer - automatic transfer from 1rzl 1uvh NO 12 12 Tetr Tetr 16030020 15178251 Interface geometry conserved with 1o9r (30%) - automatic transfer from 1veq 1uvi PROBYES 3 1 NS NPS 14962391 11242087 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands - automaticaly inferred from 1hhs_3 1uvj PROBYES 3 1 NS NPS 14962391 11242087 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands - automaticaly inferred from 1hhs_3 1uvk PROBYES 3 1 NS NPS 14962391 11242087 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands - automaticaly inferred from 1hhs_3 1uvl PROBYES 3 1 NS NPS 14962391 11242087 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands - automaticaly inferred from 1hhs_3 1uvm PROBYES 3 1 NS NPS 14962391 11242087 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands - automaticaly inferred from 1hhs_3 1uvn PROBYES 3 1 NS NPS 14962391 11242087 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - Paper says: The 664 residues of the monomeric protein form 25 alpha-helices and 21 beta-strands - automaticaly inferred from 1hhs_3 1uvo PROBNOT 1 1 NPS NPS 15840915 0 -- Annotation transfered from 1c1m 1uvp PROBNOT 1 1 NPS NPS 15840915 0 -- Annotation transfered from 1c1m 1uvr NO 1 1 NPS NPS 14962382 0 gel filtration studies suggest that PDK1 is monomeric -- Annotation transfered from 1okz 1uvw PROBNOT 1 1 NPS NPS 14764581 0 Paper says nothing, PISA says monomer -- Annotation transfered from 1hl0 1uw8 PROBNOT 6 6 D3 D3 14871895 0 Paper says hexamer - Interesting because it says that trimeric homologs also exist although they are not in PDB: The three proteins phaseolin, canavalin, and proglycinin are all classified as seed storage proteins. These seed storage proteins are trimeric bicupins with no metal binding sites but share some features of quaternary structure with the hexameric bicupin OXDC. -- SCOP dom_arch Error (2 doms) -- Annotation transfered from 1l3j 1uwh NO 2 2 C2 C2 15035987 0 Paper discuss the biological relevance of the dimer -- Annotation transfered from 1uwj 1uwi PROBNOT 4 4 D2 D2 0 9299327 The enzyme is a tetramer with subunit molecular mass at 60 kDa - automatic transfer from 1gow 1uwj NO 2 2 C2 C2 15035987 15035987 Paper discuss the biological relevance of the dimer 1uwm PROBNOT 1 1 NPS NPS 16402206 11173487 Paper mentions gel filtration and ultracentrif and no oligomer - PISA says monomer - automatic transfer from 1e9m 1uwn PROBNOT 1 1 NPS NPS 15026418 0 SP says monomer -- Annotation transfered from 1s1z 1uwq PROBNOT 4 4 D2 D2 15147194 0 The enzyme is a tetramer with subunit molecular mass at 60 kDa -- Annotation transfered from 1gow 1uwr PROBNOT 4 4 D2 D2 15147194 0 The enzyme is a tetramer with subunit molecular mass at 60 kDa -- Annotation transfered from 1gow 1uws PROBNOT 4 4 D2 D2 15147194 0 The enzyme is a tetramer with subunit molecular mass at 60 kDa -- Annotation transfered from 1gow 1uwt PROBNOT 4 4 D2 D2 15147194 0 The enzyme is a tetramer with subunit molecular mass at 60 kDa -- Annotation transfered from 1gow 1uwu PROBNOT 4 4 D2 D2 15147194 0 The enzyme is a tetramer with subunit molecular mass at 60 kDa -- Annotation transfered from 1gow 1uwy PROBNOT 1 1 NPS NPS 15066430 0 1ux9_1 PROBYES 1 2 NPS C2 15044115 15165856 BU changed since last release and is now incorrect - disulfide bonded dimer - automaticaly inferred from 1v5h 1ux9_2 PROBYES 1 2 NPS C2 15044115 15165856 BU changed since last release and is now incorrect - disulfide bonded dimer - automaticaly inferred from 1v5h 1uxg NO 4 4 D2 D2 15321717 0 Paper says tetramer -- very interesting paper: mutation introduced to increase the stability, 1 mutation increases the Tm by 24 degrees! Good support to state that it is impossible to measure structural factors responsible for a difference between mesophiles and thermophiles proteins 1uxh NO 4 4 D2 D2 15321717 0 Paper says tetramer -- very interesting paper: mutation introduced to increase the stability, 1 mutation increases the Tm by 24 degrees! Good support to state that it is impossible to measure structural factors responsible for a difference between mesophiles and thermophiles proteins -- Annotation transfered from 1uxg 1uxi NO 4 4 D2 D2 15321717 0 Paper says tetramer -- very interesting paper: mutation introduced to increase the stability, 1 mutation increases the Tm by 24 degrees! Good support to state that it is impossible to measure structural factors responsible for a difference between mesophiles and thermophiles proteins -- Annotation transfered from 1uxg 1uxj NO 4 4 D2 D2 15321717 0 Paper says tetramer -- very interesting paper: mutation introduced to increase the stability, 1 mutation increases the Tm by 24 degrees! Good support to state that it is impossible to measure structural factors responsible for a difference between mesophiles and thermophiles proteins -- Annotation transfered from 1uxg 1uxk NO 4 4 D2 D2 15321717 0 Paper says tetramer -- very interesting paper: mutation introduced to increase the stability, 1 mutation increases the Tm by 24 degrees! Good support to state that it is impossible to measure structural factors responsible for a difference between mesophiles and thermophiles proteins -- Annotation transfered from 1uxg 1uxl_1 PROBNOT 2 2 C2 C2 15056757 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1uxl_2 PROBNOT 2 2 C2 C2 15056757 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1uxl_3 PROBNOT 2 2 C2 C2 15056757 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1uxl_4 PROBNOT 2 2 C2 C2 15056757 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1uxl_5 PROBNOT 2 2 C2 C2 15056757 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1uxm_1 PROBNOT 2 2 C2 C2 15056757 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1uxm_2 PROBNOT 2 2 C2 C2 15056757 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1uxm_3 PROBNOT 2 2 C2 C2 15056757 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1uxm_4 PROBNOT 2 2 C2 C2 15056757 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1uxm_5 PROBNOT 2 2 C2 C2 15056757 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1uxm_6 PROBNOT 2 2 C2 C2 15056757 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 1uxn NO 4 4 D2 D2 15288789 0 Paper says tetramer -- Annotation transfered from 1ky8 1uxp NO 4 4 D2 D2 15288789 0 Paper says tetramer -- Annotation transfered from 1ky8 1uxq NO 4 4 D2 D2 15288789 0 Paper says tetramer -- Annotation transfered from 1ky8 1uxr NO 4 4 D2 D2 15288789 0 Paper says tetramer -- Annotation transfered from 1ky8 1uxt NO 4 4 D2 D2 15288789 0 Paper says tetramer -- Annotation transfered from 1ky8 1uxu NO 4 4 D2 D2 15288789 0 Paper says tetramer -- Annotation transfered from 1ky8 1uxv NO 4 4 D2 D2 15288789 0 Paper says tetramer -- Annotation transfered from 1ky8 1uy6 NA 1 1 NPS NPS 15217611 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization 1uy7 NA 1 1 NPS NPS 15217611 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization -- Annotation transfered from 1uy6 1uy8 NA 1 1 NPS NPS 15217611 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization -- Annotation transfered from 1uy6 1uy9 NA 1 1 NPS NPS 15217611 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization -- Annotation transfered from 1uy6 1uyc NA 1 1 NPS NPS 15217611 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization -- Annotation transfered from 1uy6 1uyd NA 1 1 NPS NPS 15217611 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization -- Annotation transfered from 1uy6 1uye NA 1 1 NPS NPS 15217611 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization -- Annotation transfered from 1uy6 1uyf NA 1 1 NPS NPS 15217611 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization -- Annotation transfered from 1uy6 1uyg NA 1 1 NPS NPS 15217611 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization -- Annotation transfered from 1uy6 1uyh NA 1 1 NPS NPS 15217611 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization -- Annotation transfered from 1uy6 1uyi NA 1 1 NPS NPS 15217611 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization -- Annotation transfered from 1uy6 1uyk NA 1 1 NPS NPS 15217611 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization -- Annotation transfered from 1uy6 1uyl NA 1 1 NPS NPS 15217611 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization -- Annotation transfered from 1uy6 1uym NA 1 1 NPS NPS 15217611 15217611 Paper says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization 1uyq PROBNOT 8 8 D4 D4 0 0 BU changed since last release and is now corrected - See similar -- PISA does not find it! - automatic transfer from 1e4i 1uyr NO 2 2 C2 C2 15079078 15079078 Paper says: These mutant proteins are still dimeric in solution as determined by light-scattering experiments (data not shown). 1uys_1 NO 2 2 C2 C2 15079078 15079078 Paper says: These mutant proteins are still dimeric in solution as determined by light-scattering experiments (data not shown). - automatic transfer from 1uyr 1uys_2 NO 2 2 C2 C2 15079078 15079078 Paper says: These mutant proteins are still dimeric in solution as determined by light-scattering experiments (data not shown). - automatic transfer from 1uyr 1uyt_1 NO 2 2 C2 C2 15079078 15079078 Paper says: These mutant proteins are still dimeric in solution as determined by light-scattering experiments (data not shown). - automatic transfer from 1uyr 1uyt_2 NO 2 2 C2 C2 15079078 15079078 Paper says: These mutant proteins are still dimeric in solution as determined by light-scattering experiments (data not shown). - automatic transfer from 1uyr 1uyu_1 PROBNOT 1 1 NPS NPS 15219983 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1uyu_2 PROBNOT 1 1 NPS NPS 15219983 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1uyv_1 PROBNOT 2 2 C2 C2 15079078 0 BU changed since last release and is now corrected - cf. 1uyr - automaticaly inferred from 1od4 1uyv_2 PROBNOT 2 2 C2 C2 15079078 0 BU changed since last release and is now corrected - cf. 1uyr - automaticaly inferred from 1od4 1uz2 PROBNOT 2 2 C2 C2 15147215 0 SP says: Under physiological conditions beta-lactoglobulin exists as an equilibrium mixture of monomeric and dimeric forms -- Annotation transfered from 2blg 1uz5 YES 1 2 NPS C2 0 0 Interface geometry conserved with 1fc5 (34%) 1uzb YES 2 6 C2 D3 16934832 16934832 BU changed since last release and is now incorrect - Paper says hexamer - very interesting: same function --> dimer / tetramer / hexamer! Evolution study would be interesting to carry out. 1uzi_1 PROBNOT 1 1 NPS NPS 15272191 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer - automatic transfer from 1gze_2 1uzi_2 PROBNOT 1 1 NPS NPS 15272191 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer - automatic transfer from 1gze_2 1uzu NO 2 2 C2 C2 15153119 0 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 1uzw PROBNOT 1 1 NPS NPS 15175003 0 No info was found, PISA says monomer. I also think it should be. 1uzy PROBNOT 2 2 C2 C2 15201215 0 1uzz_1 PROBNOT 2 2 C2 C2 15201215 0 - automatic transfer from 1uzy 1uzz_2 PROBNOT 2 2 C2 C2 15201215 0 - automatic transfer from 1uzy 1v00_1 PROBNOT 2 2 C2 C2 15201215 0 - automatic transfer from 1uzy 1v00_2 PROBNOT 2 2 C2 C2 15201215 0 - automatic transfer from 1uzy 1v02_1 NO 2 2 C2 C2 15148317 15148317 Paper says: the dimer interface of SbDhr1 is also very similar to that of the maize enzyme. - automatic transfer from 1v03 1v02_2 NO 2 2 C2 C2 15148317 15148317 Paper says: the dimer interface of SbDhr1 is also very similar to that of the maize enzyme. - automatic transfer from 1v03 1v02_3 NO 2 2 C2 C2 15148317 15148317 Paper says: the dimer interface of SbDhr1 is also very similar to that of the maize enzyme. - automatic transfer from 1v03 1v03 NO 2 2 C2 C2 15148317 15148317 Paper says: the dimer interface of SbDhr1 is also very similar to that of the maize enzyme. 1v08 PROBNOT 2 2 C2 C2 15148317 0 Paper says: It was unexpected that the E401D as well as C205S and C211S mutations dramatically impaired the assembly of a catalysis-competent homodimer, suggesting novel links between the active site structure and dimer formation. -- Interesting: link between dimer formation and catalysis -- Annotation transfered from 1hxj 1v0k PROBNOT 1 1 NPS NPS 15306887 0 Seems to be monomeric although there is no clear evidence 1v0l PROBNOT 1 1 NPS NPS 15306887 0 Seems to be monomeric although there is no clear evidence -- Annotation transfered from 1v0k 1v0m PROBNOT 1 1 NPS NPS 15306887 0 Seems to be monomeric although there is no clear evidence -- Annotation transfered from 1v0k 1v0n PROBNOT 1 1 NPS NPS 15306887 0 Seems to be monomeric although there is no clear evidence -- Annotation transfered from 1v0k 1v10 PROBNOT 1 1 NPS NPS 15364578 15364578 Paper says nothing, PISA says monomer 1v19 NO 6 6 D3 D3 15210349 0 Dynamic light-scattering measurements and gel filtration show that TtKDGK is monodisperse with a high molecular mass of 160 kDa, suggesting that TtKDGK may exist as hexamers also in solution. -- Annotation transfered from 1v1a 1v1a NO 6 6 D3 D3 15210349 15210349 Dynamic light-scattering measurements and gel filtration show that TtKDGK is monodisperse with a high molecular mass of 160 kDa, suggesting that TtKDGK may exist as hexamers also in solution. 1v1b_1 NO 6 6 D3 D3 15210349 15210349 Dynamic light-scattering measurements and gel filtration show that TtKDGK is monodisperse with a high molecular mass of 160 kDa, suggesting that TtKDGK may exist as hexamers also in solution. - automatic transfer from 1v1a 1v1b_2 NO 6 6 D3 D3 15210349 15210349 Dynamic light-scattering measurements and gel filtration show that TtKDGK is monodisperse with a high molecular mass of 160 kDa, suggesting that TtKDGK may exist as hexamers also in solution. - automatic transfer from 1v1a 1v1j NO 12 12 Tetr Tetr 15162210 11937054 Interface geometry conserved with 1h0s (43%) - automatic transfer from 1gu0 1v1k NO 1 1 NPS NPS 12941311 0 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1v1o PROBNOT 2 2 C2 C2 15213171 15213171 paper: since the crystals grew under different conditions and at markedly different pH values, it is unlikely that the dimers formed solely as a result of crystal packing forces. 1v1p PROBNOT 2 2 C2 C2 15213171 15213171 paper: since the crystals grew under different conditions and at markedly different pH values, it is unlikely that the dimers formed solely as a result of crystal packing forces. 1v1s_1 NO 6 6 D3 D3 15210349 15210349 Dynamic light-scattering measurements and gel filtration show that TtKDGK is monodisperse with a high molecular mass of 160 kDa, suggesting that TtKDGK may exist as hexamers also in solution. - automatic transfer from 1v1a 1v1s_2 NO 6 6 D3 D3 15210349 15210349 Dynamic light-scattering measurements and gel filtration show that TtKDGK is monodisperse with a high molecular mass of 160 kDa, suggesting that TtKDGK may exist as hexamers also in solution. - automatic transfer from 1v1a 1v1s_3 NO 6 6 D3 D3 15210349 15210349 Dynamic light-scattering measurements and gel filtration show that TtKDGK is monodisperse with a high molecular mass of 160 kDa, suggesting that TtKDGK may exist as hexamers also in solution. - automatic transfer from 1v1a 1v25 PROBNOT 2 2 C2 C2 15145952 15145952 Paper says dimer - domain swapped -- interesting: Yeast s one is a trimer --> same function and different QS (That s rare!!) - also interesting: a homologous prot from B. subtilis works in a non ribosomal peptide synthase (ribosome ansector?) -- Annotation transfered from 1ult 1v26 PROBNOT 2 2 C2 C2 15145952 15145952 Paper says dimer - domain swapped -- interesting: Yeast s one is a trimer --> same function and different QS (That s rare!!) - also interesting: a homologous prot from B. subtilis works in a non ribosomal peptide synthase (ribosome ansector?) -- Annotation transfered from 1ult 1v2d NO 2 2 C2 C2 14761974 14761974 1v2e NO 2 2 C2 C2 14761974 14761974 -- Annotation transfered from 1v2d 1v2f NO 2 2 C2 C2 14761974 14761974 -- Annotation transfered from 1v2d 1v2h NO 3 3 C3 C3 14680831 14680831 Paper says trimer -- Annotation transfered from 1ula 1v2j PROBNOT 1 1 NPS NPS 14729347 14729347 -- Annotation transfered from 1az8 1v2k PROBNOT 1 1 NPS NPS 14729347 14729347 -- Annotation transfered from 1az8 1v2l PROBNOT 1 1 NPS NPS 14729347 14729347 -- Annotation transfered from 1az8 1v2m PROBNOT 1 1 NPS NPS 14729347 14729347 -- Annotation transfered from 1az8 1v2n PROBNOT 1 1 NPS NPS 14729347 14729347 -- Annotation transfered from 1az8 1v2o PROBNOT 1 1 NPS NPS 14729347 14729347 -- Annotation transfered from 1az8 1v2p PROBNOT 1 1 NPS NPS 14729347 14729347 -- Annotation transfered from 1az8 1v2q PROBNOT 1 1 NPS NPS 14729347 14729347 -- Annotation transfered from 1az8 1v2r PROBNOT 1 1 NPS NPS 14729347 14729347 -- Annotation transfered from 1az8 1v2s PROBNOT 1 1 NPS NPS 14729347 14729347 -- Annotation transfered from 1az8 1v2t PROBNOT 1 1 NPS NPS 14729347 14729347 -- Annotation transfered from 1az8 1v2u PROBNOT 1 1 NPS NPS 14729347 14729347 -- Annotation transfered from 1az8 1v2v PROBNOT 1 1 NPS NPS 14729347 14729347 -- Annotation transfered from 1az8 1v2w PROBNOT 1 1 NPS NPS 14729347 14729347 -- Annotation transfered from 1az8 1v2z NO 2 2 C2 C2 15170179 15170179 Paper says: KaiA eluted at a volume corresponding to a molecular mass of 68 kDa (Fig. 3a), suggesting that it is a dimer. We confirmed this by crosslinking experiments 1v35 NO 4 4 D2 D2 15381426 0 1v39 YES 2 1 C2 NPS 9145102 9145102 SP and PISA say monomer -- Annotation transfered from 3mct 1v3h PROBNOT 1 1 NPS NPS 15178253 15178253 SP says monomer -- Annotation transfered from 1v3i 1v3i PROBNOT 1 1 NPS NPS 15178253 15178253 SP says monomer 1v3q NO 3 3 C3 C3 14706628 14706628 Paper says trimer -- Annotation transfered from 1ula 1v3r NO 3 3 C3 C3 15629661 0 Interface geometry conserved with 1pil (44%) - automatic transfer from 1ufl 1v3s NO 3 3 C3 C3 15629661 0 Interface geometry conserved with 1pil (44%) - automatic transfer from 1ufl 1v3t NO 2 2 C2 C2 15007077 15007077 -- Annotation transfered from 1v3u 1v3u NO 2 2 C2 C2 15007077 15007077 1v3v NO 2 2 C2 C2 15007077 15007077 -- Annotation transfered from 1v3u 1v3w PROBNOT 3 3 C3 C3 0 0 No info but this fold has the active site at the interface of the trimer - 1v3z YES 2 1 C2 NPS -1 15779887 Because PhAcP exists as a monomer in solution, dimerization is unlikely to be important for the biological function of the enzyme. - automatic transfer from 1w2i 1v41 PROBNOT 3 3 C3 C3 15983407 14706628 BU changed since last release and is now corrected - Paper says trimer - automaticaly inferred from 1rct 1v45 PROBNOT 3 3 C3 C3 15983407 14706628 BU changed since last release and is now corrected - Paper says trimer - automaticaly inferred from 1rct 1v47 PROBNOT 2 2 C2 C2 15065853 15065853 Paper says: TtATPS forms a dimer in the crystal, and the manner of subunit association is different from that observed in dimeric R. pachyptila symbiont ATPS and in the hexameric S. cerevisiae and P. chrysogenum ATPSs. 1v48 NO 3 3 C3 C3 15272165 15272165 Paper says trimer 1v4b PROBNOT 2 2 C2 C2 16684776 0 - automatic transfer from 1tik 1v59 NO 2 2 C2 C2 0 9538259 SP says dimer - automatic transfer from 1jeh 1v5h NO 2 2 C2 C2 15165856 15165856 disulfide bonded dimer 1v5x NO 2 2 C2 C2 15944409 0 Interface conseved with 1nsj (42%) 1v67 PROBNOT 3 3 C3 C3 0 0 No info but this fold has the active site at the interface of the trimer - -- Annotation transfered from 1v3w 1v6d PROBNOT 1 1 NPS NPS 15842169 10561533 - automatic transfer from 1qqu 1v6h PROBNOT 3 3 C3 C3 0 0 -- Annotation transfered from 1nza 1v6i NO 4 4 C2 C2 14747696 14747696 Paper says tetramer -- Annotation transfered from 2pel 1v6j NO 4 4 C2 C2 14747696 14747696 Paper says tetramer -- Annotation transfered from 2pel 1v6k NO 4 4 C2 C2 14747696 14747696 Paper says tetramer -- Annotation transfered from 2pel 1v6l NO 4 4 C2 C2 14747696 14747696 Paper says tetramer -- Annotation transfered from 2pel 1v6m_1 NO 4 4 C2 C2 14747696 8656429 Paper says tetramer - automatic transfer from 2pel 1v6m_2 NO 4 4 C2 C2 14747696 8656429 Paper says tetramer - automatic transfer from 2pel 1v6n_1 NO 4 4 C2 C2 14747696 8656429 Paper says tetramer - automatic transfer from 2pel 1v6n_2 NO 4 4 C2 C2 14747696 8656429 Paper says tetramer - automatic transfer from 2pel 1v6o_1 NO 4 4 C2 C2 14747696 8656429 Paper says tetramer - automatic transfer from 2pel 1v6o_2 NO 4 4 C2 C2 14747696 8656429 Paper says tetramer - automatic transfer from 2pel 1v7r YES 2 2 NS C2 0 0 Interface geometry conserved with 2mjp 1v7s NO 1 1 NPS NPS 15039550 15039550 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1v7t_1 NO 1 1 NPS NPS 15039550 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1v7t_2 NO 1 1 NPS NPS 15039550 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1v8a NO 3 3 C3 C3 0 0 Interface geometry conserved with 1esq (43%) 1v8j NO 1 1 NPS NPS 14980225 0 Missing dimerization coil-coil -- Annotation transfered from 1v8k 1v8k NO 1 1 NPS NPS 14980225 0 Missing dimerization coil-coil 1v8q YES 4 1 NS NPS 15340170 15340170 Paper implies monomer: There are four molecules in the crystallographic asymmetric unit - It is consistent with the results from previous studies, which showed that the conformations of ribosomal proteins in the ribosome are similar to their monomer forms in isolation 1v99_1 PROBNOT 3 3 C3 C3 0 0 - automatic transfer from 1uku 1v99_2 PROBNOT 3 3 C3 C3 0 0 - automatic transfer from 1uku 1v9b_1 PROBNOT 3 3 C3 C3 0 0 - automatic transfer from 1uku 1v9b_2 PROBNOT 3 3 C3 C3 0 0 - automatic transfer from 1uku 1v9c NO 2 2 C2 C2 0 0 Interface geometry conserved with 1f2v (43%) 1v9e_1 PROBNOT 1 1 NPS NPS 15039588 0 - automatic transfer from 1v9i 1v9e_2 PROBNOT 1 1 NPS NPS 15039588 0 - automatic transfer from 1v9i 1v9h PROBNOT 1 1 NPS NPS 15322360 10964705 No clear evidence was found. PISA says monomer - automatic transfer from 1uca 1v9i PROBNOT 1 1 NPS NPS 0 0 1v9o NO 3 3 C3 C3 15629661 0 Interface geometry conserved with 1pil (44%) - automatic transfer from 1ufl 1v9q NO 1 1 NPS NPS 15869276 0 Myoglobin is a monomeric protein (8663546) - automatic transfer from 1a6m 1va5_1 PROBNOT 1 1 NPS NPS 15192106 10655617 BU changed since last release and is now corrected - ag85C is a single-domain monomeric protein - automaticaly inferred from 1dqz 1va5_2 PROBNOT 1 1 NPS NPS 15192106 10655617 BU changed since last release and is now corrected - ag85C is a single-domain monomeric protein - automaticaly inferred from 1dqz 1vaf_1 PROBYES 2 1 C2 NPS 15071192 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1vaf_2 PROBYES 2 1 C2 NPS 15071192 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 1vag NO 2 2 C2 C2 15071192 15071192 Clear dimer -- Annotation transfered from 1m00 1val NO 4 4 D2 D2 8812993 8812993 SP says tetramer -- Annotation transfered from 1cjp 1vam NO 4 4 D2 D2 8812993 8812993 SP says tetramer -- Annotation transfered from 1cjp 1vao NO 8 8 D4 D4 9261083 9141139 Paper says octamer -- Annotation transfered from 2vao 1var NO 4 4 D2 D2 8605177 8605177 Paper says tetramer -- Annotation transfered from 1n0j 1vat NO 1 1 NPS NPS -1 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1vau NO 1 1 NPS NPS -1 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1vb0 NA 1 1 NPS NPS 15252034 12777767 Ask the persons who work with it - automatic transfer from 1onj 1vbs PROBNOT 1 1 NPS NPS 9720925 9720925 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 1vbt_1 PROBNOT 1 1 NPS NPS 0 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1vbt_2 PROBNOT 1 1 NPS NPS 0 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1vc1 NO 2 2 C2 C2 15162498 15162498 Paper says: We previously observed that the recombinant M1442 protein exists both as a monomer and as a dimer in solution. - Monomer dimer equilibrium 1vc2 PROBNOT 4 4 D2 D2 0 0 1vca_1 PROBNOT 1 1 NPS NPS 7531291 7539925 BU changed since last release and is now corrected - Paper does not mention a dimer - PISA says monomer and same sequence later crystalized as a monomer (1ij9) - automaticaly inferred from 1vsc 1vca_2 PROBNOT 1 1 NPS NPS 7531291 7539925 BU changed since last release and is now corrected - Paper does not mention a dimer - PISA says monomer and same sequence later crystalized as a monomer (1ij9) - automaticaly inferred from 1vsc 1vcp_1 PROBYES 1 2 NPS C2 9094737 9094737 BU changed since last release and is now incorrect - Interface geometry conserved with 2snw (68%) - automaticaly inferred from 1vcq 1vcp_2 PROBYES 1 2 NPS C2 9094737 9094737 BU changed since last release and is now incorrect - Interface geometry conserved with 2snw (68%) - automaticaly inferred from 1vcq 1vcp_3 PROBYES 1 2 NPS C2 9094737 9094737 BU changed since last release and is now incorrect - Interface geometry conserved with 2snw (68%) - automaticaly inferred from 1vcq 1vcq NO 2 2 C2 C2 9094737 9094737 Interface geometry conserved with 2snw (68%) 1vcw NO 3 3 C3 C3 15137941 15137941 Interface geometry conserved with 1lcy (31%) -- Annotation transfered from 1sot 1vdc NO 2 2 C2 C2 9000629 9000629 Interface conserved with 1trb (46%) 1vde PROBYES 2 1 C2 NPS 9160747 9160747 From the paper it seems to be a monomer. -- Annotation transfered from 1ef0 1vdk NO 4 4 D2 D2 0 0 Interface geometry conserved with 1tjw (23%) 1vdn NA 1 1 NPS NPS 0 0 There is no paper and no info. PISA says monomer. 1vdp_1 NO 1 1 NPS NPS 0 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1vdp_2 NO 1 1 NPS NPS 0 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1vdq NO 1 1 NPS NPS 0 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1vdr PROBYES 2 1 C2 NPS 9493269 9493269 Paper implies monomer - PISa also says monomer 1vds NO 1 1 NPS NPS 0 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1vdt NO 1 1 NPS NPS 0 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1vdw PROBNOT 2 2 C2 C2 0 0 1veb NO 1 1 NPS NPS 14998327 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 1ved NO 1 1 NPS NPS 0 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1vei NO 12 12 Tetr Tetr 15178251 15178251 Interface geometry conserved with 1o9r (30%) -- Annotation transfered from 1veq 1vel NO 12 12 Tetr Tetr 15178251 15178251 Interface geometry conserved with 1o9r (30%) -- Annotation transfered from 1veq 1veq NO 12 12 Tetr Tetr 15178251 15178251 Interface geometry conserved with 1o9r (30%) 1ver YES 1 2 NPS C2 15304650 15304650 we have also observed such dimeric species in solution - interessting: different mode of interaction 1vew_1 NO 2 2 C2 C2 -1 11294629 PAper, SP say dimer - automatic transfer from 1i0h 1vew_2 NO 2 2 C2 C2 -1 11294629 PAper, SP say dimer - automatic transfer from 1i0h 1vf7 PROBNOT 13 13 NS NS 15117957 15117957 Paper says: The 13-mer was shaped like a woven rattan cylinder with a large internal tubular space and widely opened flared ends. -- incredible protein shape 1vf8 PROBNOT 1 1 NPS NPS 15522777 11278670 Ym1 has been purified and characterized as a single chain polypeptide with an estimated molecular mass of 45 kDa - automatic transfer from 1e9l 1vfj NO 3 3 C3 C3 15629661 0 Interface geometry conserved with 1pil (44%) - automatic transfer from 1ufl 1vfn NO 3 3 C3 C3 9020983 9020983 Paper says trimer -- Annotation transfered from 1v48 1vfp YES 2 1 C2 NPS 15229613 0 It would not make sense to have a C2 symmetry as the pumps would pump in opposite directions ... 1vfv NO 1 1 NPS NPS 15286375 15286375 Missing dimerization coil-coil -- Annotation transfered from 1vfz 1vfw NO 1 1 NPS NPS 15286375 15286375 Missing dimerization coil-coil -- Annotation transfered from 1vfz 1vfx NO 1 1 NPS NPS 15286375 15286375 Missing dimerization coil-coil -- Annotation transfered from 1vfz 1vfz NO 1 1 NPS NPS 15286375 15286375 Missing dimerization coil-coil 1vga_1 NO 2 2 C2 C2 15465054 12454456 Interface geometry conserved with 1m6j (43%) - paper says dimer - automatic transfer from 1m7p 1vga_2 NO 2 2 C2 C2 15465054 12454456 Interface geometry conserved with 1m6j (43%) - paper says dimer - automatic transfer from 1m7p 1vgn YES 2 1 C2 NPS 15892033 10757977 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says nothing - PISA implies monomer - automaticaly inferred from 1ddk 1vgt NO 2 2 C2 C2 16021622 16021622 Paper says dimer: CDP-ME synthetase organizes as a homodimer with each subunit related by a crystallographic two-fold axis - SP says dimer too -- Annotation transfered from 1ini 1vgu NO 2 2 C2 C2 16021622 16021622 Paper says dimer: CDP-ME synthetase organizes as a homodimer with each subunit related by a crystallographic two-fold axis - SP says dimer too -- Annotation transfered from 1ini 1vgw_1 PROBNOT 2 2 C2 C2 16021622 16021622 Interface geometry conserved with 1vgu (44%) - automatic transfer from 1vgz 1vgw_2 PROBNOT 2 2 C2 C2 16021622 16021622 Interface geometry conserved with 1vgu (44%) - automatic transfer from 1vgz 1vgw_3 PROBNOT 2 2 C2 C2 16021622 16021622 Interface geometry conserved with 1vgu (44%) - automatic transfer from 1vgz 1vgx NO 2 2 C2 C2 16021622 16021622 -- Annotation transfered from 1vje 1vgz PROBNOT 2 2 C2 C2 16021622 16021622 Interface geometry conserved with 1vgu (44%) 1vh2 YES 1 2 NPS C2 16021622 16021622 1vh5 NA 2 2 C2 C2 16021622 16021622 No info, PISA says dimer 1vh7 PROBNOT 1 1 NPS NPS 16021622 16021622 The HisH and HisF proteins form a stable 1 : 1 dimeric complex that constitutes the IGP synthase holoenzyme. 1vh9 NA 2 2 C2 C2 16021622 16021622 No info, PISA says dimer 1vhb NO 2 2 C2 C2 9115439 9115439 Paper says dimer -- interesting example to show a benchmark of what is a good interface because the interface with 5.5 resids is almost identical to that with 11!! Why is that? 1vhd NO 2 2 C2 C2 16021622 16021622 Interfave geometry conserved with 1rrm (31%) 1vhf PROBYES 1 1 NPS NPS 16021622 16021622 1vhg NO 2 2 C2 C2 16021622 16021622 Domain swapped dimer - EcoCyc says dimer 1vhj NO 6 6 D3 D3 16021622 16021622 Interface geometry conserved with 1q1g 1vhl_1 NA 1 3 NPS C3 16021622 12538896 BU changed since last release and is now incorrect - NO info - ask crystollographers - automaticaly inferred from 1n3b 1vhl_2 NA 1 3 NPS C3 16021622 12538896 BU changed since last release and is now incorrect - NO info - ask crystollographers - automaticaly inferred from 1n3b 1vhl_3 NA 1 3 NPS C3 16021622 12538896 BU changed since last release and is now incorrect - NO info - ask crystollographers - automaticaly inferred from 1n3b 1vht_1 NA 1 3 NPS C3 16021622 12538896 BU changed since last release and is now incorrect - NO info - ask crystollographers - automaticaly inferred from 1n3b 1vht_2 NA 1 3 NPS C3 16021622 12538896 BU changed since last release and is now incorrect - NO info - ask crystollographers - automaticaly inferred from 1n3b 1vht_3 NA 1 3 NPS C3 16021622 12538896 BU changed since last release and is now incorrect - NO info - ask crystollographers - automaticaly inferred from 1n3b 1vhw NO 6 6 D3 D3 16021622 16021622 Interface geometry conserved with 1q1g -- Annotation transfered from 1vhj 1vhz NO 2 2 C2 C2 16021622 16021622 Domain swapped dimer - EcoCyc says dimer -- Annotation transfered from 1vhg 1vi2 NO 2 2 C2 C2 16021622 16021622 1vi3 YES 1 2 NPS C2 16021622 16021622 PISA is right 1vi4 YES 1 3 NPS C3 16021622 16021622 Interface geometry conserved with 1q5s (44%) 1vi8_1 NA 4 2 D2 C2 16021622 16021622 BU changed since last release and is now incorrect - No info, PISA says dimer - automaticaly inferred from 1vh5 1vi8_2 NA 4 2 D2 C2 16021622 16021622 BU changed since last release and is now incorrect - No info, PISA says dimer - automaticaly inferred from 1vh5 1via NA 2 2 C2 C2 16021622 16021622 Paper says nothing - send email 1vij NO 2 2 C2 C2 9346283 9346283 -- Annotation transfered from 1ajx 1vik NO 2 2 C2 C2 9346283 9346283 -- Annotation transfered from 1ajx 1vim NO 4 4 D2 D2 16021622 16021622 Interface geometry conserved with 1jeo (41%) 1vio YES 2 1 C2 NPS 16511038 16511038 Paper says: Finally, there is no evidence of dimer formation in solution as judged by gel-filtration chromatography of H. influenzae RsuA. The active-site clefts and catalytic residues (Asp102) are sterically blocked within the dimer and would be inaccessible to the rRNA substrate. 1vip PROBNOT 1 1 NPS NPS 9604284 9604284 SP says monomer 1vis NA 1 1 NPS NPS 16021622 16021622 Paper says: The structure of MVK contains all 312 residues of the wild-type MVK as well as five residues from the N-terminal histidine tag fusion. It is a monomer in crystal, although the dimer was reported in the aqueous solution. -- Annotation transfered from 1kkh 1viv YES 2 4 C2 D2 16021622 16021622 Interface geometry conserved with 1jeo (39%) 1viy NA 3 3 C3 C3 16021622 16021622 NO info - ask crystollographers -- Annotation transfered from 1n3b 1vj0 NO 4 4 D2 D2 0 0 Interface geometry conserved with 1piw (25%) 1vj1 PROBNOT 1 1 NPS NPS 15229897 15229897 Paper says monomer (no direct evidence is shown though) 1vj2 PROBNOT 2 2 C2 C2 15229893 15229893 Interface geometry conserved with 1o4t (34%) 1vj3 PROBNOT 1 1 NPS NPS 10736154 0 PISA also says monomer - Human is monomeric so I guess it should be - Only Thermogota seems to be dimeric -- Annotation transfered from 1cd2 1vj9 PROBNOT 1 1 NPS NPS 15150279 15150279 -- Annotation transfered from 1owd 1vja PROBNOT 1 1 NPS NPS 15150279 15150279 -- Annotation transfered from 1owd 1vjb NO 2 2 C2 C2 15161930 15161930 Paper says dimer -- Annotation transfered from 1kv6 1vje NO 2 2 C2 C2 11435117 11435117 1vjf NA 1 1 NPS NPS 0 0 No paper - no info 1vjj_1 PROBNOT 1 1 NPS NPS 14645372 11980702 BU changed since last release and is now corrected - Paper says: the protein is a monomer in solution - automaticaly inferred from 1l9m 1vjj_2 PROBNOT 1 1 NPS NPS 14645372 11980702 BU changed since last release and is now corrected - Paper says: the protein is a monomer in solution - automaticaly inferred from 1l9m 1vjm YES 6 3 C3 C3 14532280 14532280 SP says trimer -- Duplicated chains 1vjo NO 2 2 C2 C2 15657930 15657930 1vjp NO 4 4 D2 D2 0 0 Interface geometry conserved with 1gr0 (29%) 1vjs PROBNOT 1 1 NPS NPS 9163741 9163741 SP says monomer -- Annotation transfered from 1bli 1vjw PROBNOT 1 1 NPS NPS 8939753 8939753 SP says monomer 1vjy PROBNOT 1 1 NPS NPS 15317461 15317461 Paper says nothing, PISA says monomer -- Annotation transfered from 1py5 1vka PROBYES 2 1 C2 NPS 0 0 Surface < 400 sq angs, probably an artifact although it is difficult to be sure. PISA says monomer 1vke NO 6 6 D3 D3 0 0 Interface geometry conserved with 1p8c (90%) 1vkg YES 2 1 C2 NPS 15242608 15477595 The oligomerization state observed in the crystal is unlikely to occur in solution, because the results of size-exclusion chromatography and light-scattering experiments are compatible with a monomeric state for both the apoprotein and the protein–inhibitor complex. 1vki NA 2 2 C2 C2 0 0 No paper - no info 1vkj PROBYES 3 1 NS NPS 15060080 15060080 Paper says nothing, PISA says monomeric 1vkn PROBNOT 4 4 D2 D2 0 0 No paper - PISA says tetramer 1vko PROBNOT 4 4 D2 D2 0 0 No paper - PISA says tetramer -- interesting family: interface geometry not well conserved -- SCOP error? This one is twice as big as others with same dom-arch 1vkq PROBNOT 1 1 NPS NPS 15333929 0 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1o2e 1vl0 NA 3 3 C3 C3 0 0 No info - PISA says trimer 1vl8 NA 2 2 C2 C2 0 0 PISA says tetramer, and is (wrong?) with some like 1ipf which is described as a dimer in the paper. So I dont know what to think - unclear but potentially interesting. 1vl9 PROBNOT 1 1 NPS NPS 16508077 14529623 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution - automatic transfer from 1o2e 1vlg NO 24 24 Octa Octa 0 0 Interface geometry conserved with 1lb3 (28%) 1vlh PROBNOT 6 6 D3 D3 0 0 PISA says hexamer - Homologous enzymes are also hexamers 1vlj NO 2 2 C2 C2 0 0 Interfave geometry conserved with 1vhd (27%) 1vln_1 PROBNOT 4 4 D2 D2 8812975 0 BU changed since last release and is now corrected - - automaticaly inferred from 1qgl 1vln_2 PROBNOT 4 4 D2 D2 8812975 0 BU changed since last release and is now corrected - - automaticaly inferred from 1qgl 1vls NO 2 2 C2 C2 8831788 8831788 Paper says dimer -- Annotation transfered from 2lig 1vlt NO 2 2 C2 C2 8831788 8831788 Paper says dimer -- Annotation transfered from 2lig 1vlv NO 12 12 Tetr Tetr 0 0 Interface geometry conserved with 1vlv (44%) 1vlx PROBYES 4 1 D2 NPS 9094740 9094740 This is hard to believe but it seems that azurin is a monomeric protein! -- Annotation transfered from 5azu 1vlz YES 2 1 C2 NPS 7615544 7615544 CheY is a Mr 14,000 monomeric protein -- Annotation transfered from 1fqw 1vm0 NA 4 4 D2 D2 0 0 No paper, no function, no name 1vm1 PROBNOT 1 1 NPS NPS 11327849 11327849 -- Annotation transfered from 1ong 1vm6 PROBNOT 4 4 D2 D2 0 0 No paper - PISA says tetramer -- interesting family: interface geometry not well conserved 1vm7 NO 2 2 C2 C2 0 0 Interface geometry conserved with 1rkd (39%) 1vot PROBNOT 2 2 C2 C2 8989325 8989325 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. 1vp3 YES 2 1 C2 NPS 9145102 9145102 SP and PISA say monomer -- Annotation transfered from 3mct 1vp9 YES 2 1 C2 NPS 9145102 9145102 SP and PISA say monomer -- Annotation transfered from 3mct 1vpi PROBNOT 2 2 C2 C2 9054978 9054978 Can form paralogous dimers so probably relevant -- Annotation transfered from 1q5t 1vpt YES 2 1 C2 NPS 8612277 8612277 SP and PISA say monomer -- Annotation transfered from 3mct 1vq1_1 NO 1 1 NPS NPS 0 12741815 PrmC eluted at a volume consistent with a monomeric state. - automatic transfer from 1nv9 1vq1_2 NO 1 1 NPS NPS 0 12741815 PrmC eluted at a volume consistent with a monomeric state. - automatic transfer from 1nv9 1vr2 PROBNOT 1 1 NPS NPS 10368301 10368301 1vr6 NO 4 4 D2 D2 0 15276836 SP says tetramer - automatic transfer from 1rzm 1vrw PROBYES 2 4 C2 D2 11792710 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1v35 1vsb NO 1 1 NPS NPS 9425066 9425066 -- Annotation transfered from 1be6 1vsc PROBYES 2 1 C2 NPS 7539925 7539925 Paper does not mention a dimer - PISA says monomer and same sequence later crystalized as a monomer (1ij9) 1vsd NO 2 2 C2 C2 8805516 8805516 Interface is conserved with 1itg even though seq sim is ~35% so I believe this interface is functionally relevant (plus it is known to oligomerize). - very interesting -- Annotation transfered from 1cxu 1vse NO 2 2 C2 C2 8805516 8805516 Interface is conserved with 1itg even though seq sim is ~35% so I believe this interface is functionally relevant (plus it is known to oligomerize). - very interesting -- Annotation transfered from 1cxu 1vsf NO 2 2 C2 C2 8805516 8805516 Interface is conserved with 1itg even though seq sim is ~35% so I believe this interface is functionally relevant (plus it is known to oligomerize). - very interesting -- Annotation transfered from 1cxu 1vsh NO 2 2 C2 C2 9218451 9218451 Interface is conserved with 1itg even though seq sim is ~35% so I believe this interface is functionally relevant (plus it is known to oligomerize). - very interesting -- Annotation transfered from 1cxu 1vsi NO 2 2 C2 C2 9218451 9218451 Interface is conserved with 1itg even though seq sim is ~35% so I believe this interface is functionally relevant (plus it is known to oligomerize). - very interesting -- Annotation transfered from 1cxu 1vsj NO 2 2 C2 C2 9218451 9218451 Interface is conserved with 1itg even though seq sim is ~35% so I believe this interface is functionally relevant (plus it is known to oligomerize). - very interesting -- Annotation transfered from 1cxu 1vsk NO 2 2 C2 C2 9830010 9830010 Interface is conserved with 1itg even though seq sim is ~35% so I believe this interface is functionally relevant (plus it is known to oligomerize). - very interesting -- Annotation transfered from 1cxu 1vsl NO 2 2 C2 C2 9830010 9830010 Interface is conserved with 1itg even though seq sim is ~35% so I believe this interface is functionally relevant (plus it is known to oligomerize). - very interesting -- Annotation transfered from 1cxu 1vsm NO 2 2 C2 C2 9830010 9830010 Interface is conserved with 1itg even though seq sim is ~35% so I believe this interface is functionally relevant (plus it is known to oligomerize). - very interesting -- Annotation transfered from 1cxu 1vub_1 NO 2 2 C2 C2 9917404 9917404 Paper says dimer: CcdB forms a dimer in the crystal, consistent with solution studies. - automatic transfer from 3vub 1vub_2 NO 2 2 C2 C2 9917404 9917404 Paper says dimer: CcdB forms a dimer in the crystal, consistent with solution studies. - automatic transfer from 3vub 1vwa NO 4 4 D2 D2 9148939 9148939 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1vwb NO 4 4 D2 D2 9148939 9148939 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1vwc NO 4 4 D2 D2 9148939 9148939 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1vwd NO 4 4 D2 D2 9148939 9148939 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1vwe NO 4 4 D2 D2 9148939 9148939 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1vwf NO 4 4 D2 D2 9148939 9148939 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1vwg NO 4 4 D2 D2 9148939 9148939 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1vwh NO 4 4 D2 D2 9148939 9148939 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1vwi NO 4 4 D2 D2 9148939 9148939 BU changed since last release and is now corrected - -- Annotation transfered from 1vwl 1vwj NO 4 4 D2 D2 9148939 9148939 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1vwk NO 4 4 D2 D2 9148939 9148939 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1vwl NO 4 4 D2 D2 9148939 9148939 BU changed since last release and is now corrected - 1vwm NO 4 4 D2 D2 9148939 9148939 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1vwn NO 4 4 D2 D2 9148939 9148939 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1vwo NO 4 4 D2 D2 9148939 9148939 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1vwp NO 4 4 D2 D2 9148939 9148939 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1vwq NO 4 4 D2 D2 9148939 9148939 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1vwr NO 4 4 D2 D2 9148939 9148939 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 1vxa NO 1 1 NPS NPS 8642596 8642596 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1vxb NO 1 1 NPS NPS 8642596 8642596 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1vxc NO 1 1 NPS NPS 8642596 8642596 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1vxd NO 1 1 NPS NPS 8642596 8642596 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1vxe NO 1 1 NPS NPS 8642596 8642596 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1vxf NO 1 1 NPS NPS 8642596 8642596 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1vxg NO 1 1 NPS NPS 8642596 8642596 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1vxh NO 1 1 NPS NPS 8642596 8642596 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1vxo PROBNOT 1 1 NPS NPS -1 0 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1vxr PROBNOT 1 1 NPS NPS -1 0 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 1vyf PROBNOT 1 1 NPS NPS 15476393 0 1vyg PROBNOT 1 1 NPS NPS 15476393 0 -- Annotation transfered from 1vyf 1vyj_1 NO 3 3 C3 C3 15681588 8861913 - automatic transfer from 1axc 1vyj_2 NO 3 3 C3 C3 15681588 8861913 - automatic transfer from 1axc 1vym NO 3 3 C3 C3 15681588 8861913 - automatic transfer from 1axc 1vyp NO 1 1 NPS NPS 15128738 0 PETN reductase is a monomeric flavoenzyme -- Annotation transfered from 1gvo 1vyr NO 1 1 NPS NPS 15128738 0 PETN reductase is a monomeric flavoenzyme -- Annotation transfered from 1gvo 1vys NO 1 1 NPS NPS 15128738 0 PETN reductase is a monomeric flavoenzyme -- Annotation transfered from 1gvo 1vyz NO 1 1 NPS NPS 15189033 0 Cdks do not in general form homo-oligomers -- Annotation transfered from 1gij 1vza NO 2 2 C2 C2 8568895 8568895 SP says homodimer -- Annotation transfered from 4tms 1vzb NO 2 2 C2 C2 8568895 8568895 SP says homodimer -- Annotation transfered from 4tms 1vzc NO 2 2 C2 C2 8568895 8568895 SP says homodimer -- Annotation transfered from 4tms 1vzd NO 2 2 C2 C2 8568895 8568895 SP says homodimer -- Annotation transfered from 4tms 1vze NO 2 2 C2 C2 8568895 8568895 SP says homodimer -- Annotation transfered from 4tms 1vzz NO 2 2 C2 C2 15228388 0 -- Annotation transfered from 1e3v 1w00 NO 2 2 C2 C2 15228388 11007792 - automatic transfer from 1e3v 1w01 NO 2 2 C2 C2 15228388 0 -- Annotation transfered from 1e3v 1w02 NO 2 2 C2 C2 15228388 0 -- Annotation transfered from 1e3v 1w03 NA 1 1 NPS NPS 15850395 7791906 BU changed since last release and is now corrected - Might be interesting to discuss in the paper - So the difference in the two crystallised forms is a combination of the crystallisation conditions and the conformational change upon substrate binding. Biological significance? Intuitively, I would say - probably none I hope this helps, Cheers, Pete - automaticaly inferred from 1ips 1w04 NA 1 1 NPS NPS 15850395 7791906 BU changed since last release and is now corrected - Might be interesting to discuss in the paper - So the difference in the two crystallised forms is a combination of the crystallisation conditions and the conformational change upon substrate binding. Biological significance? Intuitively, I would say - probably none I hope this helps, Cheers, Pete - automaticaly inferred from 1ips 1w05 NA 1 1 NPS NPS 15850395 7791906 BU changed since last release and is now corrected - Might be interesting to discuss in the paper - So the difference in the two crystallised forms is a combination of the crystallisation conditions and the conformational change upon substrate binding. Biological significance? Intuitively, I would say - probably none I hope this helps, Cheers, Pete - automaticaly inferred from 1ips 1w06 NA 1 1 NPS NPS 15850395 7791906 BU changed since last release and is now corrected - Might be interesting to discuss in the paper - So the difference in the two crystallised forms is a combination of the crystallisation conditions and the conformational change upon substrate binding. Biological significance? Intuitively, I would say - probably none I hope this helps, Cheers, Pete - automaticaly inferred from 1ips 1w08 NO 1 1 NPS NPS 16126226 0 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1w0c_1 NO 4 4 D2 D2 15388924 0 - automatic transfer from 1e92 1w0c_2 NO 4 4 D2 D2 15388924 0 - automatic transfer from 1e92 1w0e PROBNOT 1 1 NPS NPS 15256616 15256616 Paper says nothing - 11304120 says P450s are monomeric enzymes 1w0f PROBNOT 1 1 NPS NPS 15256616 0 Paper says nothing - 11304120 says P450s are monomeric enzymes -- Annotation transfered from 1w0e 1w0g PROBNOT 1 1 NPS NPS 15256616 0 Paper says nothing - 11304120 says P450s are monomeric enzymes -- Annotation transfered from 1w0e 1w0x NO 1 1 NPS NPS 0 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 1w15 PROBYES 3 1 C3 NPS 15311271 0 paper do not talk about trimer, PISA says monomer 1w16 PROBNOT 1 1 NPS NPS 15311271 0 1w1j PROBYES 2 8 C2 D4 15169773 0 Paper says: Analytical gel filtration experiments showed that the His422 mutants are mainly in the octameric form with a small portion being present as a dimer. - dimer octamer equilibrium -- Annotation transfered from 1qlt 1w1k PROBYES 2 8 C2 D4 15169773 0 Paper says: Analytical gel filtration experiments showed that the His422 mutants are mainly in the octameric form with a small portion being present as a dimer. - dimer octamer equilibrium -- Annotation transfered from 1qlt 1w1l PROBYES 2 8 C2 D4 15169773 0 Paper says: Analytical gel filtration experiments showed that the His422 mutants are mainly in the octameric form with a small portion being present as a dimer. - dimer octamer equilibrium -- Annotation transfered from 1qlt 1w1m PROBYES 2 8 C2 D4 15169773 0 Paper says: Analytical gel filtration experiments showed that the His422 mutants are mainly in the octameric form with a small portion being present as a dimer. - dimer octamer equilibrium -- Annotation transfered from 1qlt 1w1z NO 8 8 D4 D4 15327955 15327955 Paper says octamer 1w22_1 NO 1 1 NPS NPS 15477595 15477595 The oligomerization state observed in the crystal is unlikely to occur in solution, because the results of size-exclusion chromatography and light-scattering experiments are compatible with a monomeric state for both the apoprotein and the protein–inhibitor complex. - automatic transfer from 1t67 1w22_2 NO 1 1 NPS NPS 15477595 15477595 The oligomerization state observed in the crystal is unlikely to occur in solution, because the results of size-exclusion chromatography and light-scattering experiments are compatible with a monomeric state for both the apoprotein and the protein–inhibitor complex. - automatic transfer from 1t67 1w28 PROBNOT 1 1 NPS NPS 15381427 9723623 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - this suggests that the trimeric structure of the apoenzyme found in the crystal might have some functional significance, for example in the protection of the C-terminal arm (rich in lysines and arginines) against proteases in the apo- or resting forms of DAOCS. However, DAOCS dissociates into monomers in the presence of Fe(II) and 2-oxoglutarate. - automaticaly inferred from 1hjf 1w2a PROBNOT 1 1 NPS NPS 15381427 9723623 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - this suggests that the trimeric structure of the apoenzyme found in the crystal might have some functional significance, for example in the protection of the C-terminal arm (rich in lysines and arginines) against proteases in the apo- or resting forms of DAOCS. However, DAOCS dissociates into monomers in the presence of Fe(II) and 2-oxoglutarate. - automaticaly inferred from 1hjf 1w2g NO 2 2 C2 C2 15628853 11914484 BU changed since last release and is now corrected - supperposed with itself - automatic transfer from 1gtv_1 1w2h NO 2 2 C2 C2 15628853 11914484 BU changed since last release and is now corrected - supperposed with itself - automatic transfer from 1gtv_1 1w2i YES 2 1 C2 NPS 15779887 15779887 Because PhAcP exists as a monomer in solution, dimerization is unlikely to be important for the biological function of the enzyme. 1w2m_1 NO 4 4 D2 D2 16229471 15388923 Paper says tetramer - automatic transfer from 1n51 1w2m_2 NO 4 4 D2 D2 16229471 15388923 Paper says tetramer - automatic transfer from 1n51 1w2n PROBNOT 1 1 NPS NPS 15381427 9723623 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - this suggests that the trimeric structure of the apoenzyme found in the crystal might have some functional significance, for example in the protection of the C-terminal arm (rich in lysines and arginines) against proteases in the apo- or resting forms of DAOCS. However, DAOCS dissociates into monomers in the presence of Fe(II) and 2-oxoglutarate. - automaticaly inferred from 1hjf 1w2o PROBNOT 1 1 NPS NPS 15381427 9723623 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - this suggests that the trimeric structure of the apoenzyme found in the crystal might have some functional significance, for example in the protection of the C-terminal arm (rich in lysines and arginines) against proteases in the apo- or resting forms of DAOCS. However, DAOCS dissociates into monomers in the presence of Fe(II) and 2-oxoglutarate. - automaticaly inferred from 1hjf 1w2p_1 PROBYES 1 2 NPS C2 15452124 11025547 BU changed since last release and is now incorrect - They say in the paper that there is no evidence that it forms dimers in solution - automaticaly inferred from 1e5n 1w2p_2 PROBYES 1 2 NPS C2 15452124 11025547 BU changed since last release and is now incorrect - They say in the paper that there is no evidence that it forms dimers in solution - automaticaly inferred from 1e5n 1w2u PROBNOT 1 1 NPS NPS 15364577 0 Paper says nothing, PISA says monomer -- Annotation transfered from 1uu4 1w2v_1 PROBYES 1 2 NPS C2 15452124 11025547 BU changed since last release and is now incorrect - They say in the paper that there is no evidence that it forms dimers in solution - automaticaly inferred from 1e5n 1w2v_2 PROBYES 1 2 NPS C2 15452124 11025547 BU changed since last release and is now incorrect - They say in the paper that there is no evidence that it forms dimers in solution - automaticaly inferred from 1e5n 1w2x_1 NO 2 2 C2 C2 15341732 15079078 Paper says: These mutant proteins are still dimeric in solution as determined by light-scattering experiments (data not shown). - automatic transfer from 1uyr 1w2x_2 NO 2 2 C2 C2 15341732 15079078 Paper says: These mutant proteins are still dimeric in solution as determined by light-scattering experiments (data not shown). - automatic transfer from 1uyr 1w2z_1 NO 2 2 C2 C2 15533431 8805580 Interface geometry conserved with 1sii (25%) - automatic transfer from 1ksi 1w2z_2 NO 2 2 C2 C2 15533431 8805580 Interface geometry conserved with 1sii (25%) - automatic transfer from 1ksi 1w31 NO 8 8 D4 D4 16131755 11545591 BU changed since last release and is now corrected - Paper says octamer - automatic transfer from 1h7o 1w32_1 PROBYES 1 2 NPS C2 15452124 11025547 BU changed since last release and is now incorrect - They say in the paper that there is no evidence that it forms dimers in solution - automaticaly inferred from 1e5n 1w32_2 PROBYES 1 2 NPS C2 15452124 11025547 BU changed since last release and is now incorrect - They say in the paper that there is no evidence that it forms dimers in solution - automaticaly inferred from 1e5n 1w34 NO 1 1 NPS NPS 16216071 8890910 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) - automatic transfer from 1que 1w35 NO 1 1 NPS NPS 16216071 8890910 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) - automatic transfer from 1que 1w37 NO 4 4 D2 D2 15265860 0 Paper says tetramer -- interesting dom arch: all are tetramers but different interf. geometry! Again, convergent evolution? -- Annotation transfered from 1w3t 1w3h_1 PROBYES 1 2 NPS C2 15452124 11025547 BU changed since last release and is now incorrect - They say in the paper that there is no evidence that it forms dimers in solution - automaticaly inferred from 1e5n 1w3h_2 PROBYES 1 2 NPS C2 15452124 11025547 BU changed since last release and is now incorrect - They say in the paper that there is no evidence that it forms dimers in solution - automaticaly inferred from 1e5n 1w3i NO 4 4 D2 D2 15265860 0 Paper says tetramer -- interesting dom arch: all are tetramers but different interf. geometry! Again, convergent evolution? -- Annotation transfered from 1w3t 1w3n NO 4 4 D2 D2 15265860 0 Paper says tetramer -- interesting dom arch: all are tetramers but different interf. geometry! Again, convergent evolution? -- Annotation transfered from 1w3t 1w3t NO 4 4 D2 D2 15265860 15265860 Paper says tetramer -- interesting dom arch: all are tetramers but different interf. geometry! Again, convergent evolution? 1w3u PROBYES 1 2 NPS C2 15608117 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1bt4 1w3v NA 1 1 NPS NPS 16444759 7791906 BU changed since last release and is now corrected - Might be interesting to discuss in the paper - So the difference in the two crystallised forms is a combination of the crystallisation conditions and the conformational change upon substrate binding. Biological significance? Intuitively, I would say - probably none I hope this helps, Cheers, Pete - automaticaly inferred from 1ips 1w3x NA 1 1 NPS NPS 16444759 7791906 BU changed since last release and is now corrected - Might be interesting to discuss in the paper - So the difference in the two crystallised forms is a combination of the crystallisation conditions and the conformational change upon substrate binding. Biological significance? Intuitively, I would say - probably none I hope this helps, Cheers, Pete - automaticaly inferred from 1ips 1w4l PROBYES 2 4 C2 NA 15563167 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 1w4n NO 2 2 C2 C2 0 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 1w4o_1 PROBNOT 1 1 NPS NPS 15670155 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1w4o_2 PROBNOT 1 1 NPS NPS 15670155 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1w4p_1 PROBNOT 1 1 NPS NPS 15670155 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1w4p_2 PROBNOT 1 1 NPS NPS 15670155 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1w4q_1 PROBNOT 1 1 NPS NPS 15670155 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1w4q_2 PROBNOT 1 1 NPS NPS 15670155 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1w4w PROBNOT 1 1 NPS NPS 15641789 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1gx2 1w4x NO 1 1 NPS NPS 15328411 15328411 PAMO is a monomeric 62-kDa enzyme that catalyses the conversion of phenylacetone to phenylacetate 1w4y PROBNOT 1 1 NPS NPS 15641789 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1gx2 1w5g NO 4 4 D2 D2 16584182 0 Paper says tetramer -- error with the symmetry search? -- four helix bundle ... not very relevant 1w5h NO 4 4 D2 D2 16584182 0 Paper says tetramer -- error with the symmetry search? -- Annotation transfered from 1w5g 1w5i NO 4 4 C4 C4 16584182 0 Paper says tetramer -- Annotation transfered from 1gcl 1w5l NO 4 4 C4 C4 16584182 0 Paper says tetramer -- Annotation transfered from 1gcl 1w5v NO 2 2 C2 C2 15560801 9083478 - automatic transfer from 1ajx 1w5w NO 2 2 C2 C2 15560801 9083478 - automatic transfer from 1ajx 1w5y NO 2 2 C2 C2 15560801 9083478 - automatic transfer from 1ajx 1w5z NO 2 2 C2 C2 0 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 1w60_1 NO 3 3 C3 C3 15681588 8861913 - automatic transfer from 1axc 1w60_2 NO 3 3 C3 C3 15681588 8861913 - automatic transfer from 1axc 1w6c NO 2 2 C2 C2 0 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 1w6g NO 2 2 C2 C2 0 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 1w6l PROBNOT 1 1 NPS NPS 16234932 14764581 Paper says nothing, PISA says monomer - automatic transfer from 1hl0 1w6r PROBYES 2 4 C2 NA 15563167 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 1w6w PROBNOT 1 1 NPS NPS 16234932 14764581 Paper says nothing, PISA says monomer - automatic transfer from 1hl0 1w6y NO 2 2 C2 C2 15819891 11007792 - automatic transfer from 1e3v 1w6z NO 1 1 NPS NPS 0 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1w75 PROBYES 2 4 C2 NA 15563167 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 1w76 PROBYES 2 4 C2 NA 15563167 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 1w7h PROBNOT 1 1 NPS NPS 15658854 11896401 - automatic transfer from 1kv1 1w7l NO 2 2 C2 C2 15364907 0 -- Annotation transfered from 1w7n 1w7m NO 2 2 C2 C2 15364907 0 -- Annotation transfered from 1w7n 1w7n NO 2 2 C2 C2 15364907 0 1w7o PROBNOT 1 1 NPS NPS 15456779 7966289 Paper not available - PISa says monomer and related prots are monomeric. - automatic transfer from 2cy3 1w7p YES 8 4 NS NPS 15469844 15469844 Wrong reconstruction 1w7v_1 NO 4 4 D2 D2 16229471 15388923 Paper says tetramer - automatic transfer from 1n51 1w7v_2 NO 4 4 D2 D2 16229471 15388923 Paper says tetramer - automatic transfer from 1n51 1w82 PROBNOT 1 1 NPS NPS 15658855 11896401 - automatic transfer from 1kv1 1w83 PROBNOT 1 1 NPS NPS 15658855 11896401 - automatic transfer from 1kv1 1w84 PROBNOT 1 1 NPS NPS 15658855 11896401 - automatic transfer from 1kv1 1w87_1 NO 1 1 NPS NPS 16216071 8890910 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) - automatic transfer from 1que 1w87_2 NO 1 1 NPS NPS 16216071 8890910 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) - automatic transfer from 1que 1w8c NO 1 1 NPS NPS 0 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 1w8e PROBNOT 1 1 NPS NPS 16234932 14764581 Paper says nothing, PISA says monomer - automatic transfer from 1hl0 1w8l PROBNOT 1 1 NPS NPS 14993672 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1w8m PROBNOT 1 1 NPS NPS 14993672 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1w8v PROBNOT 1 1 NPS NPS 14993672 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1w92 PROBYES 6 1 D3 NPS 15548613 15162488 BU changed since last release and is now incorrect - SP says monomer - automaticaly inferred from 1q1f 1w9b PROBYES 1 2 NPS C2 15889170 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1e70 1w9d PROBYES 1 2 NPS C2 15889170 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1e70 1wa0 NO 3 3 C3 C3 15610025 0 Active site at the monomer-monomer interface - automatic transfer from 1oe3 1wa1 NO 3 3 C3 C3 15610025 0 Active site at the monomer-monomer interface - automatic transfer from 1oe3 1wa2 NO 3 3 C3 C3 15610025 0 Active site at the monomer-monomer interface - automatic transfer from 1oe3 1wad PROBNOT 1 1 NPS NPS 8819167 8819167 Paper says nothing, PISA says monomer 1wae NO 3 3 C3 C3 15554622 0 Active site at the monomer-monomer interface - automatic transfer from 1oe3 1was YES 1 2 NPS C2 8486661 8486661 dimeric 1wat NO 2 2 C2 C2 8486661 8486661 Paper says dimer -- Annotation transfered from 2lig 1waw NO 1 1 NPS NPS 15664516 12639956 Monomer: paper says: the enzyme occurs in two major forms of 39 and 50 kDa. The subsequent cloning of its cDNA from a macrophage library showed that the 50-kDa form can be converted to the 39-kDa form post-translationally or by RNA processing - automatic transfer from 1hki 1wax PROBNOT 1 1 NPS NPS 15658854 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1wb0 NO 1 1 NPS NPS 15664516 12639956 Monomer: paper says: the enzyme occurs in two major forms of 39 and 50 kDa. The subsequent cloning of its cDNA from a macrophage library showed that the 50-kDa form can be converted to the 39-kDa form post-translationally or by RNA processing - automatic transfer from 1hki 1wb4_1 NA 1 2 NPS C2 15681871 11738044 BU changed since last release and is now incorrect - Paper says nothing - email sent - automatic transfer from 1gkl_2 1wb4_2 NA 1 2 NPS C2 15681871 11738044 BU changed since last release and is now incorrect - Paper says nothing - email sent - automatic transfer from 1gkl_2 1wb5_1 NA 1 2 NPS C2 15681871 11738044 BU changed since last release and is now incorrect - Paper says nothing - email sent - automatic transfer from 1gkl_2 1wb5_2 NA 1 2 NPS C2 15681871 11738044 BU changed since last release and is now incorrect - Paper says nothing - email sent - automatic transfer from 1gkl_2 1wb6_1 NA 1 2 NPS C2 15681871 11738044 BU changed since last release and is now incorrect - Paper says nothing - email sent - automatic transfer from 1gkl_2 1wb6_2 NA 1 2 NPS C2 15681871 11738044 BU changed since last release and is now incorrect - Paper says nothing - email sent - automatic transfer from 1gkl_2 1wbf YES 2 2 C2 C2 10089310 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. 1wbk NO 2 2 C2 C2 0 9083478 - automatic transfer from 1ajx 1wbl_1 YES 2 2 C2 C2 9500920 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. - automatic transfer from 1wbf 1wbl_2 YES 2 2 C2 C2 9500920 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. - automatic transfer from 1wbf 1wbm NO 2 2 C2 C2 0 9083478 - automatic transfer from 1ajx 1wbn PROBNOT 1 1 NPS NPS 15658855 11896401 - automatic transfer from 1kv1 1wbo PROBNOT 1 1 NPS NPS 15658854 11896401 - automatic transfer from 1kv1 1wbq_1 NO 4 4 D2 D2 16229471 15388923 Paper says tetramer - automatic transfer from 1n51 1wbq_2 NO 4 4 D2 D2 16229471 15388923 Paper says tetramer - automatic transfer from 1n51 1wbs PROBNOT 1 1 NPS NPS 15658855 11896401 - automatic transfer from 1kv1 1wbt PROBNOT 1 1 NPS NPS 15658855 11896401 - automatic transfer from 1kv1 1wbu_1 PROBNOT 1 1 NPS NPS 15658854 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1wbu_2 PROBNOT 1 1 NPS NPS 15658854 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1wbv PROBNOT 1 1 NPS NPS 15658855 11896401 - automatic transfer from 1kv1 1wbw PROBNOT 1 1 NPS NPS 15658855 11896401 - automatic transfer from 1kv1 1wcc NO 1 1 NPS NPS 15658854 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 1wcy NO 2 2 C2 C2 15255191 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 1wdn PROBNOT 1 1 NPS NPS 9571045 9571045 EcoCyc says monomer 1wdp PROBNOT 1 1 NPS NPS 15794648 15178253 SP says monomer - automatic transfer from 1v3i 1wdq PROBNOT 1 1 NPS NPS 15794648 15178253 SP says monomer - automatic transfer from 1v3i 1wdr PROBNOT 1 1 NPS NPS 15794648 15178253 SP says monomer - automatic transfer from 1v3i 1wds PROBNOT 1 1 NPS NPS 15794648 15178253 SP says monomer - automatic transfer from 1v3i 1we2 PROBNOT 1 1 NPS NPS 15583379 12054870 SP says monomer - automatic transfer from 1l4u 1we3 NO 21 21 NPS C7 15296740 15296740 1wef PROBNOT 1 1 NPS NPS 15326180 15326180 Ecocyc says monomer -- Annotation transfered from 1kg3 1weg PROBNOT 1 1 NPS NPS 15326180 15326180 Ecocyc says monomer -- Annotation transfered from 1kg3 1wei PROBNOT 1 1 NPS NPS 15326180 15326180 Ecocyc says monomer -- Annotation transfered from 1kg3 1wfc PROBNOT 1 1 NPS NPS 8910361 8910361 -- Annotation transfered from 1kv1 1wgi PROBNOT 2 2 C2 C2 8994974 8994974 SP says dimer 1wgj PROBNOT 2 2 C2 C2 8994974 8994974 SP says dimer -- Annotation transfered from 1wgi 1who PROBYES 2 1 C2 NPS 0 0 PISA says monomer - I am not sure 1whp PROBNOT 1 1 NPS NPS 0 0 PISA says monomer - I am not sure 1wl6 NO 4 4 D2 D2 16229471 15388923 Paper says tetramer - automatic transfer from 1n51 1wl9 NO 4 4 D2 D2 16229471 15388923 Paper says tetramer - automatic transfer from 1n51 1wla NO 1 1 NPS NPS 9300804 9300804 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1wlr NO 4 4 D2 D2 16229471 15388923 Paper says tetramer - automatic transfer from 1n51 1wlu NO 4 4 D2 D2 16061252 16061252 Paper says tetramer - automatic transfer from 1j1y 1wlv_1 NO 4 4 D2 D2 16061252 16061252 Paper says tetramer - automatic transfer from 1j1y 1wlv_2 NO 4 4 D2 D2 16061252 16061252 Paper says tetramer - automatic transfer from 1j1y 1wm0 PROBYES 1 2 NPS C2 15258145 15258145 PISA says homodimer and identicals are homodimers 1wm1 PROBNOT 1 1 NPS NPS 12893291 12893291 Interface geometry sort of conserved with 1ivy (<30% id) -- Annotation transfered from 1qtr 1wm6_1 NO 4 4 D2 D2 16061252 16061252 Paper says tetramer - automatic transfer from 1j1y 1wm6_2 NO 4 4 D2 D2 16061252 16061252 Paper says tetramer - automatic transfer from 1j1y 1wmn NO 2 2 C2 C2 16142901 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 1wmo NO 2 2 C2 C2 16142901 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 1wmp NO 2 2 C2 C2 16142901 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 1wmy NO 2 2 C2 C2 15319425 15319425 CEL-I forms a disulfide-linked homodimer 1wmz_1 NO 2 2 C2 C2 15319425 15319425 CEL-I forms a disulfide-linked homodimer - automatic transfer from 1wmy 1wmz_2 NO 2 2 C2 C2 15319425 15319425 CEL-I forms a disulfide-linked homodimer - automatic transfer from 1wmy 1wn3_1 NO 4 4 D2 D2 16061252 16061252 Paper says tetramer - automatic transfer from 1j1y 1wn3_2 NO 4 4 D2 D2 16061252 16061252 Paper says tetramer - automatic transfer from 1j1y 1wnt PROBNOT 4 4 D2 D2 15906319 15103634 BU changed since last release and is now corrected - XRs from human and four rodents (mouse, rat, guinea pig, and hamster) are tetramers with each subunit consisting of 244 amino acid residues. - automaticaly inferred from 1pr9 1woa_1 NO 2 2 C2 C2 15465054 12454456 Interface geometry conserved with 1m6j (43%) - paper says dimer - automatic transfer from 1m7p 1woa_2 NO 2 2 C2 C2 15465054 12454456 Interface geometry conserved with 1m6j (43%) - paper says dimer - automatic transfer from 1m7p 1wob_1 NO 2 2 C2 C2 15465054 12454456 Interface geometry conserved with 1m6j (43%) - paper says dimer - automatic transfer from 1m7p 1wob_2 NO 2 2 C2 C2 15465054 12454456 Interface geometry conserved with 1m6j (43%) - paper says dimer - automatic transfer from 1m7p 1wog NO 6 6 D3 D3 15355972 15355972 interface geometry conserved with 1gq7 (34%) -- Annotation transfered from 1woi 1woh NO 6 6 D3 D3 15355972 15355972 interface geometry conserved with 1gq7 (34%) -- Annotation transfered from 1woi 1woi NO 6 6 D3 D3 15355972 15355972 interface geometry conserved with 1gq7 (34%) 1wpg YES 4 1 NS NPS 15448704 12167852 BU changed since last release and is now incorrect - This is clearly a crystal contact - automaticaly inferred from 1iwo 1wq1 PROBNOT 2 2 NPS NPS 9219684 16483931 Paper points to this structure as being biological -- Annotation transfered from 2c5l_1 1wqm NO 1 1 NPS NPS 9649316 9649316 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1wqn NO 1 1 NPS NPS 9649316 9649316 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1wqo NO 1 1 NPS NPS 9649316 9649316 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1wqp NO 1 1 NPS NPS 9649316 9649316 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1wqq NO 1 1 NPS NPS 9649316 9649316 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1wqr NO 1 1 NPS NPS 9649316 9649316 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1wr5 PROBNOT 1 1 NPS NPS 14581238 14581238 Paper says nothing, PISA says monomer - automatic transfer from 1j0o 1wrp NO 2 2 C2 C2 3375234 3375234 -- Annotation transfered from 1jhg 1wsb PROBNOT 1 1 NPS NPS 0 11264581 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins - automatic transfer from 1f4p 1wsd NO 1 1 NPS NPS 9278275 10493860 - automatic transfer from 1c9n 1wsw PROBYES 2 1 C2 NPS 0 11264581 BU changed since last release and is now incorrect - 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins - automaticaly inferred from 1f4p 1wtl YES 4 2 C2 C2 7993911 7993911 Paper says dimer 1wtm NO 1 1 NPS NPS 15735330 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1wtn NO 1 1 NPS NPS 15735330 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1wua PROBNOT 1 1 NPS NPS 16406066 11932258 BU changed since last release and is now corrected - Actin does not form closed dimer - automaticaly inferred from 1lcu 1wut PROBYES 2 2 C2 C2 15987904 9384557 Wrong interface of the dimer - automatic transfer from 2amv 1wuy PROBYES 2 2 C2 C2 15987904 9384557 Wrong interface of the dimer - automatic transfer from 2amv 1wv0 PROBYES 2 2 C2 C2 15987904 9384557 Wrong interface of the dimer - automatic transfer from 2amv 1wv1 PROBYES 2 2 C2 C2 15987904 9384557 Wrong interface of the dimer - automatic transfer from 2amv 1wvj PROBNOT 2 2 C2 C2 15794751 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1wvp NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) - automatic transfer from 1a6m 1ww2 PROBYES 2 2 C2 C2 16213146 9384557 Wrong interface of the dimer - automatic transfer from 2amv 1ww3 PROBYES 2 2 C2 C2 16213146 9384557 Wrong interface of the dimer - automatic transfer from 2amv 1wxj NA 1 1 NPS NPS 0 0 No paper, PISA says monomer but related proteins are dimeric - automatic transfer from 1ujp 1wyi PROBYES 4 2 C2 C2 16511037 0 BU changed since last release and is now incorrect - Interface geometry conserved with 1m6j (50%) - automaticaly inferred from 1r2t 1wyk_1 NA 1 1 NPS NPS 9779796 8450538 Unclear, email sent - automatic transfer from 2snv 1wyk_2 NA 1 1 NPS NPS 9779796 8450538 Unclear, email sent - automatic transfer from 2snv 1wyk_3 NA 1 1 NPS NPS 9779796 8450538 Unclear, email sent - automatic transfer from 2snv 1wyk_4 NA 1 1 NPS NPS 9779796 8450538 Unclear, email sent - automatic transfer from 2snv 1wze PROBNOT 2 2 C2 C2 0 8471603 SP says dimer - automatic transfer from 1bmd 1wzi PROBNOT 2 2 C2 C2 0 8471603 SP says dimer - automatic transfer from 1bmd 1x0i YES 6 3 C3 C3 16023672 14532280 SP says trimer -- Duplicated chains - automatic transfer from 1vjm 1x0k PROBNOT 3 3 C3 C3 16023672 14532280 BU changed since last release and is now corrected - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1x0s PROBNOT 3 3 C3 C3 16084526 14532280 BU changed since last release and is now corrected - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1x11 PROBYES 2 1 NS NPS 9321393 9321393 Paper shows a monomer -- Annotation transfered from 1aqc 1x1p PROBNOT 1 1 NPS NPS 16367755 11274461 SP says monomer - automatic transfer from 1io2 1x1z NO 2 2 C2 C2 16248642 12011084 SP says dimer - interface geometry conserved with 1q6q (26%) - automatic transfer from 1lor 1x28 NO 2 2 C2 C2 15938611 7896726 Interface geometry conserved with 2ay6 (45%) - automatic transfer from 1amr 1x29 NO 2 2 C2 C2 15938611 7896726 Interface geometry conserved with 2ay6 (45%) - automatic transfer from 1amr 1x2a NO 2 2 C2 C2 15938611 7896726 Interface geometry conserved with 2ay6 (45%) - automatic transfer from 1amr 1x2b PROBNOT 1 1 NPS NPS 16452443 10467172 Interface geometry sort of conserved with 1ivy (<30% id) - automatic transfer from 1qtr 1x2e PROBNOT 1 1 NPS NPS 16452443 10467172 Interface geometry sort of conserved with 1ivy (<30% id) - automatic transfer from 1qtr 1x6l PROBNOT 1 1 NPS NPS 0 9495026 BU changed since last release and is now corrected - The weight they find in that paper is compatible with a monomer - automaticaly inferred from 1ctn 1x6n PROBNOT 1 1 NPS NPS 0 9495026 BU changed since last release and is now corrected - The weight they find in that paper is compatible with a monomer - automaticaly inferred from 1ctn 1x6u PROBNOT 4 4 D2 D2 16023668 11371194 BU changed since last release and is now corrected - - automaticaly inferred from 1g7u 1x70 NO 2 2 C2 C2 15634008 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 1x71_1 PROBNOT 1 1 NPS NPS 15642259 10684642 BU changed since last release and is now corrected - Neutrophil gelatinase associated lipocalin (NGAL), a member of the lipocalin family, is released from neutrophil granules as a 25 kDa monomer, a 46 kDa disulfide-linked homodimer, and a disulfide-linked heterodimer with gelatinase B (matrix metalloproteinase 9) - this one is not linked by a S-S bond. - automaticaly inferred from 1qqs 1x71_2 PROBNOT 1 1 NPS NPS 15642259 10684642 BU changed since last release and is now corrected - Neutrophil gelatinase associated lipocalin (NGAL), a member of the lipocalin family, is released from neutrophil granules as a 25 kDa monomer, a 46 kDa disulfide-linked homodimer, and a disulfide-linked heterodimer with gelatinase B (matrix metalloproteinase 9) - this one is not linked by a S-S bond. - automaticaly inferred from 1qqs 1x71_3 PROBNOT 1 1 NPS NPS 15642259 10684642 BU changed since last release and is now corrected - Neutrophil gelatinase associated lipocalin (NGAL), a member of the lipocalin family, is released from neutrophil granules as a 25 kDa monomer, a 46 kDa disulfide-linked homodimer, and a disulfide-linked heterodimer with gelatinase B (matrix metalloproteinase 9) - this one is not linked by a S-S bond. - automaticaly inferred from 1qqs 1x77 NO 2 2 C2 C2 16552139 16552139 1x83 PROBYES 2 1 C2 NPS 15643873 12540835 Seems to be a monomer - PISA would be wrong - automatic transfer from 1nfs 1x84 PROBYES 2 1 C2 NPS 15643873 12540835 Seems to be a monomer - PISA would be wrong - automatic transfer from 1nfs 1x88_1 PROBNOT 1 1 NPS NPS 0 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 1x88_2 PROBNOT 1 1 NPS NPS 0 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 1x89_1 PROBNOT 1 1 NPS NPS 15642259 10684642 BU changed since last release and is now corrected - Neutrophil gelatinase associated lipocalin (NGAL), a member of the lipocalin family, is released from neutrophil granules as a 25 kDa monomer, a 46 kDa disulfide-linked homodimer, and a disulfide-linked heterodimer with gelatinase B (matrix metalloproteinase 9) - this one is not linked by a S-S bond. - automaticaly inferred from 1qqs 1x89_2 PROBNOT 1 1 NPS NPS 15642259 10684642 BU changed since last release and is now corrected - Neutrophil gelatinase associated lipocalin (NGAL), a member of the lipocalin family, is released from neutrophil granules as a 25 kDa monomer, a 46 kDa disulfide-linked homodimer, and a disulfide-linked heterodimer with gelatinase B (matrix metalloproteinase 9) - this one is not linked by a S-S bond. - automaticaly inferred from 1qqs 1x89_3 PROBNOT 1 1 NPS NPS 15642259 10684642 BU changed since last release and is now corrected - Neutrophil gelatinase associated lipocalin (NGAL), a member of the lipocalin family, is released from neutrophil granules as a 25 kDa monomer, a 46 kDa disulfide-linked homodimer, and a disulfide-linked heterodimer with gelatinase B (matrix metalloproteinase 9) - this one is not linked by a S-S bond. - automaticaly inferred from 1qqs 1x8f PROBNOT 4 4 D2 D2 16023668 11371194 BU changed since last release and is now corrected - - automaticaly inferred from 1g7u 1x8r PROBNOT 1 1 NPS NPS 15736934 13129913 SP says monomer - automatic transfer from 1q36 1x8s PROBNOT 1 1 NPS NPS 15475968 15023337 Paper says nothing, PISA says monomer and related proteins are monomeric - automatic transfer from 1rzx 1x8t PROBNOT 1 1 NPS NPS 15736934 13129913 SP says monomer - automatic transfer from 1q36 1x8u_1 PROBNOT 1 1 NPS NPS 15642259 10684642 BU changed since last release and is now corrected - Neutrophil gelatinase associated lipocalin (NGAL), a member of the lipocalin family, is released from neutrophil granules as a 25 kDa monomer, a 46 kDa disulfide-linked homodimer, and a disulfide-linked heterodimer with gelatinase B (matrix metalloproteinase 9) - this one is not linked by a S-S bond. - automaticaly inferred from 1qqs 1x8u_2 PROBNOT 1 1 NPS NPS 15642259 10684642 BU changed since last release and is now corrected - Neutrophil gelatinase associated lipocalin (NGAL), a member of the lipocalin family, is released from neutrophil granules as a 25 kDa monomer, a 46 kDa disulfide-linked homodimer, and a disulfide-linked heterodimer with gelatinase B (matrix metalloproteinase 9) - this one is not linked by a S-S bond. - automaticaly inferred from 1qqs 1x8u_3 PROBNOT 1 1 NPS NPS 15642259 10684642 BU changed since last release and is now corrected - Neutrophil gelatinase associated lipocalin (NGAL), a member of the lipocalin family, is released from neutrophil granules as a 25 kDa monomer, a 46 kDa disulfide-linked homodimer, and a disulfide-linked heterodimer with gelatinase B (matrix metalloproteinase 9) - this one is not linked by a S-S bond. - automaticaly inferred from 1qqs 1x8v PROBNOT 1 1 NPS NPS 15530358 0 11304120 says P450s are monomeric enzymes - automatic transfer from 1u13 1x94 PROBYES 2 4 C2 D2 16477602 0 Interface geometry conserved with 1tk9 (44%) 1x96 NO 1 1 NPS NPS 15317464 15317464 SwissProt and PISA say monomer -- Annotation transfered from 1ads 1x97 NO 1 1 NPS NPS 15317464 15317464 SwissProt and PISA say monomer -- Annotation transfered from 1ads 1x98 NO 1 1 NPS NPS 15317464 15317464 SwissProt and PISA say monomer -- Annotation transfered from 1ads 1xa5 PROBNOT 1 1 NPS NPS 15596444 3145979 - automatic transfer from 3cln 1xaf PROBYES 2 1 C2 NPS 16498617 16498617 The monomeric character was confirmed by size-exclusion chromatography 1xan NO 2 2 C2 C2 8626496 8626496 Paper says dimer -- Annotation transfered from 5grt 1xar NA 4 2 C2 C2 15509576 11739956 BU changed since last release and is now incorrect - I dont get if it is a dimer or not? - In the DC-SIGN crystals, GlcNAc1 also forms a typical C-type lectin Ca2+ coordination and hydrogen bond network at the principal Ca2+ site on the partner monomer in the dimer, thereby cross-linking the two monomers - automaticaly inferred from 1k9j 1xas PROBNOT 1 1 NPS NPS 8063693 8063693 Seems to be monomeric although there is no clear evidence -- Annotation transfered from 1v0k 1xat NO 3 3 C3 C3 9578552 9578552 Paper says trimer 1xb3_1 PROBNOT 1 1 NPS NPS 15449946 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1xb3_2 PROBNOT 1 1 NPS NPS 15449946 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1xb4_1 NA 2 2 C2 C2 15579210 15579210 Paper says: The dimer contact is mediated by hydrophobic residues Pro5, Pro6, Val7, Phe10, Pro11, and Pro12, which is similar to the contact region described for Vps25 interactions with Vps22 and Vps36 - but the interaction observed is quite different from that seen in 1u5t 1xb6_1 PROBNOT 1 1 NPS NPS 15449946 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1xb6_2 PROBNOT 1 1 NPS NPS 15449946 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1xb7 NO 2 2 C2 C2 15337744 15337744 The purified protein is a homodimer as evidenced by size-exclusion chromatography coupled to light scattering 1xb8_1 PROBNOT 1 1 NPS NPS 15449946 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1xb8_2 PROBNOT 1 1 NPS NPS 15449946 0 This is hard to believe but it seems that azurin is a monomeric protein! - automatic transfer from 1azu 1xbo PROBNOT 1 1 NPS NPS 15482920 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 1xbu PROBNOT 1 1 NPS NPS 0 11484227 SwissProt says monomer - automatic transfer from 1f2o 1xbv NO 2 2 C2 C2 15697207 14567674 Interface geometry conserved with 1lor - automatic transfer from 1q6q 1xbx NO 2 2 C2 C2 15697207 14567674 Interface geometry conserved with 1lor - automatic transfer from 1q6q 1xby NO 2 2 C2 C2 15697207 14567674 Interface geometry conserved with 1lor - automatic transfer from 1q6q 1xbz NO 2 2 C2 C2 15697207 14567674 Interface geometry conserved with 1lor - automatic transfer from 1q6q 1xc7 PROBYES 2 2 C2 C2 15653344 9384557 Wrong interface of the dimer - automatic transfer from 2amv 1xc8 PROBNOT 1 1 NPS NPS 15249553 15249553 SP says monomer and a review says that these prots are monomeric - automatic transfer from 1tdz 1xca PROBYES 2 1 NS NPS 9600845 9737849 Apo-CRABPII is largely monomeric in solution 1xch NO 1 1 NPS NPS 9300804 9300804 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1xcm NO 1 1 NPS NPS 0 10574788 Ras proteins are monomeric G proteins - automatic transfer from 1ctq 1xcv NO 2 2 C2 C2 0 7568230 Interface geometry conserved down to 30% with 1on1 - automatic transfer from 1dpr 1xdd_1 PROBNOT 1 1 NPS NPS 15304496 7479767 BU changed since last release and is now corrected - Interface very small - probably monomer - automaticaly inferred from 1lfa 1xdd_2 PROBNOT 1 1 NPS NPS 15304496 7479767 BU changed since last release and is now corrected - Interface very small - probably monomer - automaticaly inferred from 1lfa 1xdg_1 PROBNOT 1 1 NPS NPS 15304496 7479767 BU changed since last release and is now corrected - Interface very small - probably monomer - automaticaly inferred from 1lfa 1xdg_2 PROBNOT 1 1 NPS NPS 15304496 7479767 BU changed since last release and is now corrected - Interface very small - probably monomer - automaticaly inferred from 1lfa 1xds PROBNOT 2 2 C2 C2 15548527 14607118 BU changed since last release and is now corrected - Interface geometry conserved with 1tw2 (50% id) - automaticaly inferred from 1r00 1xdu YES 1 2 NPS C2 15548527 14607118 Interface geometry conserved with 1tw2 (50% id) - automatic transfer from 1r00 1xea NO 4 4 D2 D2 0 0 Interface geometry conserved with 1tlt (32%) 1xeg PROBNOT 1 1 NPS NPS 0 8987974 9000633 says monomeric - automatic transfer from 1uga 1xei NO 1 1 NPS NPS 9714162 9714162 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1xej NO 1 1 NPS NPS 9714162 9714162 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1xek NO 1 1 NPS NPS 9714162 9714162 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 1xel NO 2 2 C2 C2 8611497 8611497 SP says homodimer -- Annotation transfered from 2udp 1xem NO 1 1 NPS NPS 15796505 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1xen NO 1 1 NPS NPS 15796505 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1xeo NO 1 1 NPS NPS 15796505 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 1xep NO 1 1 NPS NPS 15916423 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1xer NA 2 2 C2 C2 8836097 8836097 No info 1xev_1 PROBNOT 1 1 NPS NPS 0 8987974 9000633 says monomeric - automatic transfer from 1uga 1xev_2 PROBNOT 1 1 NPS NPS 0 8987974 9000633 says monomeric - automatic transfer from 1uga 1xev_3 PROBNOT 1 1 NPS NPS 0 8987974 9000633 says monomeric - automatic transfer from 1uga 1xev_4 PROBNOT 1 1 NPS NPS 0 8987974 9000633 says monomeric - automatic transfer from 1uga 1xey NO 6 6 D3 D3 15735332 12912902 Paper says hexamer - automatic transfer from 1pmo 1xf0 PROBNOT 1 1 NPS NPS 15087468 14996743 PISA says it is a monomer, and relative are too. - automatic transfer from 1s1r 1xfp_2 NO 1 1 NPS NPS 15383540 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1xgi_1 PROBNOT 1 1 NPS NPS 15796528 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1xgi_2 PROBNOT 1 1 NPS NPS 15796528 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1xgj_1 PROBNOT 1 1 NPS NPS 15796528 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1xgj_2 PROBNOT 1 1 NPS NPS 15796528 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 1xgm YES 2 1 C2 NPS 9811545 9811545 Paper says: PfMAP is a monomer in solution with a molecular mass of 32,740 Da. 1xgn_1 NO 1 1 NPS NPS 9811545 9811545 Paper says: PfMAP is a monomer in solution with a molecular mass of 32,740 Da. - automatic transfer from 1xgo 1xgn_2 NO 1 1 NPS NPS 9811545 9811545 Paper says: PfMAP is a monomer in solution with a molecular mass of 32,740 Da. - automatic transfer from 1xgo 1xgo NO 1 1 NPS NPS 9811545 9811545 Paper says: PfMAP is a monomer in solution with a molecular mass of 32,740 Da. 1xgs YES 2 1 C2 NPS 9811545 9811545 Paper says: PfMAP is a monomer in solution with a molecular mass of 32,740 Da. -- Annotation transfered from 1xgm 1xh4_1 NO 1 1 NPS NPS 15634010 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 1xh5_1 NO 1 1 NPS NPS 15634010 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 1xh6_1 NO 1 1 NPS NPS 15634010 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 1xh7_1 NO 1 1 NPS NPS 15634010 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 1xh8_1 NO 1 1 NPS NPS 15634010 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 1xha_1 NA 1 1 NPS NPS 15634010 8251932 BU changed since last release and is now corrected - Paper does not mention an oligomer - automaticaly inferred from 1cmk 1xhl NO 4 4 D2 D2 0 0 PISA says tetramer and I believe it 1xhy PROBNOT 2 2 C2 C2 15591246 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 1xi2 NO 2 2 C2 C2 16129418 10433694 - automatic transfer from 1qr2 1xib NO 4 4 D2 D2 15299449 0 -- Annotation transfered from 4xis 1xic NO 4 4 D2 D2 15299449 0 -- Annotation transfered from 4xis 1xid NO 4 4 D2 D2 15299449 0 -- Annotation transfered from 4xis 1xie NO 4 4 D2 D2 15299449 0 -- Annotation transfered from 4xis 1xif NO 4 4 D2 D2 15299449 0 -- Annotation transfered from 4xis 1xig NO 4 4 D2 D2 15299449 0 -- Annotation transfered from 4xis 1xih NO 4 4 D2 D2 15299449 0 -- Annotation transfered from 4xis 1xii NO 4 4 D2 D2 15299449 0 -- Annotation transfered from 4xis 1xij NO 4 4 D2 D2 15299449 0 -- Annotation transfered from 4xis 1xim NO 4 4 D2 D2 1540579 1540579 -- Annotation transfered from 5xin 1xin NO 4 4 D2 D2 1610791 1610791 -- Annotation transfered from 5xin 1xis NO 4 4 D2 D2 2006134 2006134 -- Annotation transfered from 4xis 1xiv NO 4 4 D2 D2 15978953 15117937 BU changed since last release and is now corrected - SP says tetramer - automatic transfer from 1t25 1xj0 NO 1 1 NPS NPS 0 10574788 Ras proteins are monomeric G proteins - automatic transfer from 1ctq 1xj7 PROBNOT 1 1 NPS NPS 15563469 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 1xjb PROBYES 2 1 C2 NPS 15929998 12899831 BU changed since last release and is now incorrect - Swissprot and PISA say it is a monomer - automaticaly inferred from 1mrq 1xji YES 1 3 NPS C3 15689517 14532280 BU changed since last release and is now incorrect - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 1xjo PROBNOT 1 1 NPS NPS 9048953 9048953 SwissProt says monomer -- Annotation transfered from 1f2o 1xka PROBNOT 2 2 NPS NPS 9618463 9618463 SP says: The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds -- Annotation transfered from 1nfw 1xkj NO 2 2 C2 C2 9020763 9020763 Paper says: Luciferase, as isolated from Vibrio harveyi, is an alpha beta heterodimer. When allowed to fold in the absence of the alpha subunit, either in vitro or in vivo, the beta subunit of enzyme will form a kinetically stable homodimer that does not unfold even after prolonged incubation in 5 M urea at pH 7.0 and 18 degrees C. -- Annotation transfered from 1bsl 1xkk NA 1 1 NPS NPS 15374980 12196540 The present data do not permit us to conclude that these contacts also arise in a cellular context - paper says that the protein may form dimers or even oligomers but they are not sure about these contacts - automatic transfer from 1m17 1xkv YES 2 2 NS C2 16239727 16239727 Paper says dimer - Interface geometry conserved with 1ii2 (44%) -- this version is wrong, but PISa gives the right one -- good example for power of conservation in curation process. - automatic transfer from 1j3b 1xkx PROBYES 1 2 NPS C2 15741340 9384557 BU changed since last release and is now incorrect - Wrong interface of the dimer - automaticaly inferred from 2amv 1xl0 PROBYES 1 2 NPS C2 15741340 9384557 BU changed since last release and is now incorrect - Wrong interface of the dimer - automaticaly inferred from 2amv 1xl1 PROBYES 1 2 NPS C2 15741340 9384557 BU changed since last release and is now incorrect - Wrong interface of the dimer - automaticaly inferred from 2amv 1xl2 NO 2 2 C2 C2 15822136 9083478 - automatic transfer from 1ajx 1xl5 NO 2 2 C2 C2 15822136 9083478 - automatic transfer from 1ajx 1xla NO 4 4 D2 D2 2319597 2319597 -- Annotation transfered from 1xlg 1xlb NO 4 4 D2 D2 2319597 2319597 -- Annotation transfered from 1xlg 1xlc NO 4 4 D2 D2 2319597 2319597 -- Annotation transfered from 1xlg 1xld NO 4 4 D2 D2 2319597 2319597 -- Annotation transfered from 1xlg 1xle NO 4 4 D2 D2 2319597 2319597 -- Annotation transfered from 1xlg 1xlf NO 4 4 D2 D2 2319597 2319597 -- Annotation transfered from 1xlg 1xlg NO 4 4 D2 D2 2319597 2319597 1xlh NO 4 4 D2 D2 2319597 2319597 -- Annotation transfered from 1xlg 1xli NO 4 4 D2 D2 2319597 2319597 -- Annotation transfered from 1xlg 1xlj NO 4 4 D2 D2 2319597 2319597 -- Annotation transfered from 1xlg 1xlk NO 4 4 D2 D2 2319597 2319597 -- Annotation transfered from 1xlg 1xll NO 4 4 D2 D2 2319597 2319597 -- Annotation transfered from 1xlg 1xlm NO 4 4 D2 D2 2319597 2319597 -- Annotation transfered from 1xlg 1xlu NO 1 1 NPS NPS 15667209 12869558 As expected (24 –28), the overall structure of BChE is very similar to that of TcAChE. However, BChE does not form the dimer observed in previous structures of TcAChE (5, 29), mouse AChE (30, 31), and human AChE (32). - automatic transfer from 1p0m 1xlv NO 1 1 NPS NPS 15667209 12869558 As expected (24 –28), the overall structure of BChE is very similar to that of TcAChE. However, BChE does not form the dimer observed in previous structures of TcAChE (5, 29), mouse AChE (30, 31), and human AChE (32). - automatic transfer from 1p0m 1xlw NO 1 1 NPS NPS 15667209 12869558 As expected (24 –28), the overall structure of BChE is very similar to that of TcAChE. However, BChE does not form the dimer observed in previous structures of TcAChE (5, 29), mouse AChE (30, 31), and human AChE (32). - automatic transfer from 1p0m 1xm1 PROBNOT 1 1 NPS NPS 0 11053836 - automatic transfer from 1doj 1xms ART 6 6 NS NS 15610008 1731253 BU changed since last release and is now corrected - - automaticaly inferred from 1rea 1xmv ART 6 6 NS NS 15610008 1731253 BU changed since last release and is now corrected - - automaticaly inferred from 1rea 1xnb PROBNOT 1 1 NPS NPS 0 0 Paper says nothing and PISA says monomer 1xnc PROBNOT 1 1 NPS NPS 7700870 7700870 Paper says nothing and PISA says monomer -- Annotation transfered from 1xnb 1xnk_1 PROBNOT 1 1 NPS NPS 15853815 12653995 BU changed since last release and is now corrected - according to the dynamic light scattering measurements, the protein was a monomer. PISA is wrong - automaticaly inferred from 1h1a 1xnk_2 PROBNOT 1 1 NPS NPS 15853815 12653995 BU changed since last release and is now corrected - according to the dynamic light scattering measurements, the protein was a monomer. PISA is wrong - automaticaly inferred from 1h1a 1xnn PROBNOT 1 1 NPS NPS 15603938 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 1xns PROBNOT 4 4 C4 C4 15591069 9288963 BU changed since last release and is now corrected - Paper shows a tetramer, is generally a tetramer, and PISA do find a cyclic tetramer. So the interfaces do exist in the crystal! - automaticaly inferred from 1crx 1xo0 PROBNOT 4 4 C4 C4 15591069 9288963 BU changed since last release and is now corrected - Paper shows a tetramer, is generally a tetramer, and PISA do find a cyclic tetramer. So the interfaces do exist in the crystal! - automaticaly inferred from 1crx 1xom_1 PROBYES 1 4 NPS D2 15576036 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1xom_2 PROBYES 1 4 NPS D2 15576036 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1xon_1 PROBYES 1 4 NPS D2 15576036 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1xon_2 PROBYES 1 4 NPS D2 15576036 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1xoq_1 PROBYES 1 4 NPS D2 15576036 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1xoq_2 PROBYES 1 4 NPS D2 15576036 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1xor_1 PROBYES 1 4 NPS D2 15576036 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1xor_2 PROBYES 1 4 NPS D2 15576036 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1xow PROBNOT 1 1 NPS NPS 15525515 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 1xoz PROBNOT 1 1 NPS NPS 15576036 15260978 No info about oligomer in all papers, PISA says monomer - automatic transfer from 1tbf 1xp0 PROBNOT 1 1 NPS NPS 15576036 15260978 No info about oligomer in all papers, PISA says monomer - automatic transfer from 1tbf 1xp1 NO 2 2 C2 C2 15582421 9338790 paper says dimer - automatic transfer from 1err 1xp5 PROBNOT 1 1 NPS NPS 15618517 12167852 BU changed since last release and is now corrected - This is clearly a crystal contact - automaticaly inferred from 1iwo 1xp6 NO 2 2 C2 C2 15582421 9338790 paper says dimer - automatic transfer from 1err 1xp9 NO 2 2 C2 C2 15582421 9338790 paper says dimer - automatic transfer from 1err 1xpb PROBNOT 1 1 NPS NPS 15299797 0 EcoCyc says monomer -- Annotation transfered from 1jwp 1xpc NO 2 2 C2 C2 15582421 9338790 paper says dimer - automatic transfer from 1err 1xph NA 1 2 NPS C2 15784257 11739956 BU changed since last release and is now incorrect - I dont get if it is a dimer or not? - In the DC-SIGN crystals, GlcNAc1 also forms a typical C-type lectin Ca2+ coordination and hydrogen bond network at the principal Ca2+ site on the partner monomer in the dimer, thereby cross-linking the two monomers - automaticaly inferred from 1k9j 1xpk_1 NO 2 2 C2 C2 15498869 15292254 - automatic transfer from 1tvz 1xpk_2 NO 2 2 C2 C2 15498869 15292254 - automatic transfer from 1tvz 1xpl_1 NO 2 2 C2 C2 15498869 15292254 - automatic transfer from 1tvz 1xpl_2 NO 2 2 C2 C2 15498869 15292254 - automatic transfer from 1tvz 1xpm_1 NO 2 2 C2 C2 15498869 15292254 - automatic transfer from 1tvz 1xpm_2 NO 2 2 C2 C2 15498869 15292254 - automatic transfer from 1tvz 1xps_1 PROBNOT 1 1 NPS NPS 10089510 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1xps_2 PROBNOT 1 1 NPS NPS 10089510 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1xpt_1 PROBNOT 1 1 NPS NPS 10089510 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1xpt_2 PROBNOT 1 1 NPS NPS 10089510 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1xpz PROBNOT 1 1 NPS NPS 15865431 8987974 9000633 says monomeric - automatic transfer from 1uga 1xq0 PROBNOT 1 1 NPS NPS 15865431 8987974 9000633 says monomeric - automatic transfer from 1uga 1xq3 PROBNOT 1 1 NPS NPS 15525515 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 1xqc_1 NO 2 2 C2 C2 15658851 9338790 paper says dimer - automatic transfer from 1err 1xqc_2 NO 2 2 C2 C2 15658851 9338790 paper says dimer - automatic transfer from 1err 1xqd PROBNOT 1 1 NPS NPS 15313618 10671516 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer - automatic transfer from 1cmj 1xqh_1 PROBNOT 1 1 NPS NPS 15525938 12372304 Paper says all SET proteins are monomeric - automatic transfer from 1muf 1xqh_2 PROBNOT 1 1 NPS NPS 15525938 12372304 Paper says all SET proteins are monomeric - automatic transfer from 1muf 1xra PROBYES 2 4 C2 D2 8550549 8550549 Paper says tetramer -- Annotation transfered from 1xrc 1xrb YES 2 4 C2 D2 8550549 8550549 Paper says tetramer 1xrc PROBYES 2 4 C2 D2 8550549 8550549 Paper says tetramer 1xrg NO 3 3 C3 C3 0 0 Interface conserved with 1jd1 (50% seq id) 1xry NO 1 1 NPS NPS 0 10413478 Aminopeptidase from Aeromonas proteolytica (AAP) is a small, monomeric enzyme (32KDa) - automatic transfer from 1cp6 1xt6 PROBNOT 1 1 NPS NPS 15805604 11264581 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins - automatic transfer from 1f4p 1xuc_1 PROBNOT 1 1 NPS NPS 15734645 10074939 BU changed since last release and is now corrected - - automaticaly inferred from 456c 1xuc_2 PROBNOT 1 1 NPS NPS 15734645 10074939 BU changed since last release and is now corrected - - automaticaly inferred from 456c 1xud_1 PROBNOT 1 1 NPS NPS 15734640 10074939 BU changed since last release and is now corrected - - automaticaly inferred from 456c 1xud_2 PROBNOT 1 1 NPS NPS 15734640 10074939 BU changed since last release and is now corrected - - automaticaly inferred from 456c 1xuf PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1xug PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1xuh PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1xui PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1xuj PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1xuk PROBNOT 1 1 NPS NPS 9468142 9468142 -- Annotation transfered from 1az8 1xuo_1 PROBNOT 1 1 NPS NPS 15686945 7479767 BU changed since last release and is now corrected - Interface very small - probably monomer - automaticaly inferred from 1lfa 1xuo_2 PROBNOT 1 1 NPS NPS 15686945 7479767 BU changed since last release and is now corrected - Interface very small - probably monomer - automaticaly inferred from 1lfa 1xur PROBYES 2 1 C2 NPS 15734640 10074939 - automatic transfer from 456c 1xva NO 4 4 D2 D2 8810903 8810903 Paper says tetramer -- Annotation transfered from 1d2h 1xvm PROBNOT 1 1 NPS NPS 16041079 11134922 - automatic transfer from 1gdn 1xvo PROBNOT 1 1 NPS NPS 16041079 11134922 - automatic transfer from 1gdn 1xw5 NO 2 2 C2 C2 0 8182750 - automatic transfer from 1hna 1xwf NO 4 4 D2 D2 16061414 10387078 SP says tetramer, interface geometry conserved among rat and human. - automatic transfer from 1b3r 1xxn PROBNOT 1 1 NPS NPS 0 0 Paper says nothing and PISA says monomer - automatic transfer from 1xnb 1xxp_1 PROBNOT 1 1 NPS NPS 15720545 8052312 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1ypt 1xxp_2 PROBNOT 1 1 NPS NPS 15720545 8052312 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1ypt 1xxv_1 PROBNOT 1 1 NPS NPS 15720545 8052312 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1ypt 1xxv_2 PROBNOT 1 1 NPS NPS 15720545 8052312 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1ypt 1xya NO 4 4 D2 D2 8180169 8180169 -- Annotation transfered from 1s5m 1xyb NO 4 4 D2 D2 8180169 8180169 -- Annotation transfered from 1s5m 1xyc NO 4 4 D2 D2 8180169 8180169 -- Annotation transfered from 1s5m 1xyl NO 4 4 D2 D2 7906142 7906142 -- Annotation transfered from 1s5m 1xym NO 4 4 D2 D2 7906142 7906142 -- Annotation transfered from 1s5m 1xyn PROBYES 2 1 C2 NPS 7827044 7827044 1xyv PROBNOT 1 1 NPS NPS 0 11264581 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins - automatic transfer from 1f4p 1xyy PROBYES 2 1 C2 NPS 0 11264581 BU changed since last release and is now incorrect - 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins - automaticaly inferred from 1f4p 1xz1 NO 24 24 Octa Octa 15791007 0 Interface geometry conserved with 1lb3 (80%) - automatic transfer from 1ies 1xz3 NO 24 24 Octa Octa 15791007 0 Interface geometry conserved with 1lb3 (80%) - automatic transfer from 1ies 1xz8 PROBYES 2 4 C2 D2 15716449 15716449 BU changed since last release and is now incorrect - PyrR eluted from high-performance liquid chromatography (HPLC) molecular sieving chromatography as a single symmetrical peak with an elution time corresponding to a native molecular weight of 77,000. This indicates that the native protein is a tetramer. In contrast, B. subtilis PyrR crystallized in hexameric and dimeric states, corresponding to molecular weights of 120,000 and 40,000, respectively (26), but migrated on gel filtration chromatography as though it had an intermediate molecular weight (27). This has been interpreted as resulting from rapid equilibration between the dimeric and hexameric states (27). Analysis of B. subtilis PyrR by HPLC under the same conditions used for B. caldolyticus PyrR yielded a molecular weight of 110,000 (21). The dimeric state of B. subtilis PyrR crystallized only in the presence of Sm2+, which fortuitously eliminated the hexamer by coordinating amino acid side chains at hexamer subunit contacts. It will be shown below that crystalline B. caldolyticus PyrR is a tetramer. - interesting story - automaticaly inferred from 1non 1xzn PROBYES 2 4 C2 D2 15716449 15716449 BU changed since last release and is now incorrect - PyrR eluted from high-performance liquid chromatography (HPLC) molecular sieving chromatography as a single symmetrical peak with an elution time corresponding to a native molecular weight of 77,000. This indicates that the native protein is a tetramer. In contrast, B. subtilis PyrR crystallized in hexameric and dimeric states, corresponding to molecular weights of 120,000 and 40,000, respectively (26), but migrated on gel filtration chromatography as though it had an intermediate molecular weight (27). This has been interpreted as resulting from rapid equilibration between the dimeric and hexameric states (27). Analysis of B. subtilis PyrR by HPLC under the same conditions used for B. caldolyticus PyrR yielded a molecular weight of 110,000 (21). The dimeric state of B. subtilis PyrR crystallized only in the presence of Sm2+, which fortuitously eliminated the hexamer by coordinating amino acid side chains at hexamer subunit contacts. It will be shown below that crystalline B. caldolyticus PyrR is a tetramer. - interesting story - automaticaly inferred from 1non 1xzx PROBNOT 1 1 NPS NPS 15466465 9808622 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Others are monomers, paper says nothing and PISA says monomer. - automaticaly inferred from 1bsx 1y0p PROBNOT 1 1 NPS NPS 0 10581550 SP says monomer - automatic transfer from 1qjd 1y0s_1 YES 1 2 NPS C2 10809235 10198642 BU changed since last release and is now incorrect - Either dimer or monomer but not not symmetrical dimer - automaticaly inferred from 3gwx 1y0s_2 YES 1 2 NPS C2 10809235 10198642 BU changed since last release and is now incorrect - Either dimer or monomer but not not symmetrical dimer - automaticaly inferred from 3gwx 1y0x PROBNOT 1 1 NPS NPS 15466465 9808622 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Others are monomers, paper says nothing and PISA says monomer. - automaticaly inferred from 1bsx 1y1d NO 4 4 D2 D2 15689188 11106758 - automatic transfer from 1g1o 1y1m_1 PROBNOT 1 1 NPS NPS 15996549 12805203 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Native structure should be a dimer but crystallizes as a monomer (membranne protein) - automaticaly inferred from 1pbq 1y1m_2 PROBNOT 1 1 NPS NPS 15996549 12805203 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Native structure should be a dimer but crystallizes as a monomer (membranne protein) - automaticaly inferred from 1pbq 1y1z PROBNOT 1 1 NPS NPS 15996549 12805203 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Native structure should be a dimer but crystallizes as a monomer (membranne protein) - automaticaly inferred from 1pbq 1y20 PROBNOT 1 1 NPS NPS 15996549 12805203 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Native structure should be a dimer but crystallizes as a monomer (membranne protein) - automaticaly inferred from 1pbq 1y2b_1 PROBYES 1 4 NPS D2 15685167 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1y2b_2 PROBYES 1 4 NPS D2 15685167 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1y2c_1 PROBYES 1 4 NPS D2 15685167 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1y2c_2 PROBYES 1 4 NPS D2 15685167 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1y2d_1 PROBYES 1 4 NPS D2 15685167 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1y2d_2 PROBYES 1 4 NPS D2 15685167 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1y2e_1 PROBYES 1 4 NPS D2 15685167 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1y2e_2 PROBYES 1 4 NPS D2 15685167 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1y2f PROBNOT 1 1 NPS NPS 15743191 10880432 BU changed since last release and is now corrected - No oligomer mentioned - PISA says monomer - automaticaly inferred from 1f46 1y2g_1 PROBNOT 1 1 NPS NPS 15743191 10880432 BU changed since last release and is now corrected - No oligomer mentioned - PISA says monomer - automaticaly inferred from 1f46 1y2g_2 PROBNOT 1 1 NPS NPS 15743191 10880432 BU changed since last release and is now corrected - No oligomer mentioned - PISA says monomer - automaticaly inferred from 1f46 1y2k_1 PROBYES 1 4 NPS D2 15685167 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1y2k_2 PROBYES 1 4 NPS D2 15685167 12842049 BU changed since last release and is now incorrect - the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automaticaly inferred from 1oyn 1y38 PROBYES 2 1 NS NPS 0 0 SP says monomer - automatic transfer from 1oxl 1y3a_1 PROBYES 4 1 C2 NPS 16004878 7481799 BU changed since last release and is now incorrect - Normally part of a heterotrimer, so apparently no homo-interaction. - automaticaly inferred from 1gdd 1y3u PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1az8 1y3v PROBNOT 1 1 NPS NPS 16374786 0 - automatic transfer from 1az8 1y3w PROBNOT 1 1 NPS NPS 16374786 0 - automatic transfer from 1az8 1y3x PROBNOT 1 1 NPS NPS 16374786 0 - automatic transfer from 1az8 1y3y PROBNOT 1 1 NPS NPS 16374786 0 - automatic transfer from 1az8 1y6q NO 2 2 C2 C2 15746096 12496243 Paper implies dimer - Dimer conserved with the dimer of the related hexameric form - automatic transfer from 1nc3 1y6r NO 2 2 C2 C2 15746096 12496243 Paper implies dimer - Dimer conserved with the dimer of the related hexameric form - automatic transfer from 1nc3 1y7t PROBNOT 2 2 C2 C2 16009341 8471603 SP says dimer - automatic transfer from 1bmd 1y8y NO 1 1 NPS NPS 15686876 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 1y91 NO 1 1 NPS NPS 15686876 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 1ya4 PROBYES 3 6 C3 D3 16081098 12725862 BU changed since last release and is now incorrect - exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automaticaly inferred from 1mx1 1ya8 PROBYES 3 6 C3 D3 16081098 12725862 BU changed since last release and is now incorrect - exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automaticaly inferred from 1mx1 1yac NO 8 8 D4 D4 9782055 9782055 Paper says: ycaCgp elutes as a complex of 180 kDa in size-exclusion chromatography -- Interface geometry of the dimer seems conserved with 1nf9 (26%) 1yah PROBYES 3 6 C3 D3 16081098 12725862 BU changed since last release and is now incorrect - exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automaticaly inferred from 1mx1 1yai_1 YES 2 2 C2 C2 8917495 9878406 Wrong interface of the dimer - automatic transfer from 1bzo 1yai_2 YES 2 2 NS C2 8917495 9878406 BU changed since last release and is now incorrect - Wrong interface of the dimer - automaticaly inferred from 1bzo 1yaj_1 PROBYES 3 6 C3 D3 16081098 12725862 BU changed since last release and is now incorrect - exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automaticaly inferred from 1mx1 1yaj_2 PROBYES 3 6 C3 D3 16081098 12725862 BU changed since last release and is now incorrect - exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automaticaly inferred from 1mx1 1yaj_3 PROBYES 3 6 C3 D3 16081098 12725862 BU changed since last release and is now incorrect - exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automaticaly inferred from 1mx1 1yaj_4 PROBYES 3 6 C3 D3 16081098 12725862 BU changed since last release and is now incorrect - exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automaticaly inferred from 1mx1 1yal PROBYES 2 1 C2 NPS 8973203 8973203 Family is monomeric and PISA says monomer (doesnt look like a native contact to me either) 1yam NO 1 1 NPS NPS 7473760 7473760 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1yan NO 1 1 NPS NPS 7473760 7473760 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1yao NO 1 1 NPS NPS 7473760 7473760 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1yap NO 1 1 NPS NPS 7473760 7473760 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1yaq NO 1 1 NPS NPS 7473760 7473760 Lysozyme C is monomeric -- Annotation transfered from 1lzr 1yas NO 2 2 C2 C2 8805565 8805565 BU changed since last release and is now corrected - PISA, SP, paper and I say homodimer -- Annotation transfered from 7yas 1yat PROBNOT 1 1 NPS NPS 7681823 7681823 Similar proteins are monomeric, no dimer mentioned in the paper and PISA says monomer 1yaz NO 2 2 C2 C2 10026301 10026301 SOD is a dimer -- Annotation transfered from 2jcw 1yb6 NO 2 2 C2 C2 17250917 14998991 PISA, SP, paper and I say homodimer - automatic transfer from 1sc9 1yb7 NO 2 2 C2 C2 17250917 14998991 PISA, SP, paper and I say homodimer - automatic transfer from 1sc9 1ybg PROBYES 4 1 D2 NPS 15701635 10823915 BU changed since last release and is now incorrect - MurA crystallizes from PEG 20000 as a monomeric species. - automaticaly inferred from 1eyn 1ybv NO 4 4 D2 D2 8939741 8939741 Said in paper that it is a tetramer -- Annotation transfered from 1g0o 1yc1 NA 1 1 NPS NPS 15713410 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automatic transfer from 1uy6 1yc2_1 PROBNOT 1 1 NPS NPS 15780941 12408821 - automatic transfer from 1ma3 1yc2_2 PROBNOT 1 1 NPS NPS 15780941 12408821 - automatic transfer from 1ma3 1yc2_3 PROBNOT 1 1 NPS NPS 15780941 12408821 - automatic transfer from 1ma3 1yc2_4 PROBNOT 1 1 NPS NPS 15780941 12408821 - automatic transfer from 1ma3 1yc2_5 PROBNOT 1 1 NPS NPS 15780941 12408821 - automatic transfer from 1ma3 1yc3 NA 1 1 NPS NPS 15713410 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automatic transfer from 1uy6 1yc4 NA 1 1 NPS NPS 15713410 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automatic transfer from 1uy6 1yca_1 NO 1 1 NPS NPS 8241160 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1yca_2 NO 1 1 NPS NPS 8241160 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1ycb_1 NO 1 1 NPS NPS 8241160 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1ycb_2 NO 1 1 NPS NPS 8241160 7612611 Myoglobin is well known to be monomeric - automatic transfer from 1mnh 1ycc PROBYES 2 1 C2 NPS 2166169 2166169 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1cih 1yci NO 2 2 C2 C2 15913349 0 BU changed since last release and is now corrected - 12432100 says: Furthermore, the structure reveals the presence of a FIH-1 homodimer that forms in solution and is essential for FIH activity. - automatic transfer from 1h2n 1ycq PROBYES 2 1 C2 NPS 8875929 8875929 1ycr PROBNOT 1 1 NPS NPS 8875929 8875929 cf. 1rv1 1yda PROBNOT 1 1 NPS NPS 7696263 7696263 9000633 says monomeric -- Annotation transfered from 1uga 1ydb PROBNOT 1 1 NPS NPS 7696263 7696263 9000633 says monomeric -- Annotation transfered from 1uga 1ydc PROBNOT 1 1 NPS NPS 7696263 7696263 9000633 says monomeric -- Annotation transfered from 1uga 1ydd PROBNOT 1 1 NPS NPS 7696263 7696263 9000633 says monomeric -- Annotation transfered from 1uga 1ydr NO 1 1 NPS NPS 8824261 8824261 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1yds NO 1 1 NPS NPS 8824261 8824261 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1ydt NO 1 1 NPS NPS 8824261 8824261 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 1ydv NO 2 2 C2 C2 9261072 9261072 Interface geometry conserved with 1m6j (43%) - paper says dimer -- Annotation transfered from 1m7p 1ye3 PROBNOT 2 2 C2 C2 0 9132002 BU changed since last release and is now corrected - - automaticaly inferred from 1lde 1yea PROBYES 2 1 C2 NPS 1326054 8401228 Paper implies it is a monomer 1yeb PROBYES 2 1 C2 NPS 1326054 8401228 Paper implies it is a monomer 1yer NA 2 1 C2 NPS 9108479 9108479 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization 1yes NA 1 1 NPS NPS 9108479 9108479 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization -- Annotation transfered from 1uy6 1yet NA 1 1 NPS NPS 9108479 9108479 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization -- Annotation transfered from 1uy6 1yf4 PROBNOT 1 1 NPS NPS 15854654 10561533 - automatic transfer from 1qqu 1yfe NO 4 4 D2 D2 16204892 9098893 Interface geometry conserved with 1q5n (22%) - automatic transfer from 1fur 1yfm NO 4 4 D2 D2 9665847 9665847 Interface geometry conserved with 1aos (21%) 1yfp_1 PROBNOT 1 1 NPS NPS 9782051 9145105 BU changed since last release and is now corrected - - automaticaly inferred from 1emc 1yfp_2 PROBNOT 1 1 NPS NPS 9782051 9145105 BU changed since last release and is now corrected - - automaticaly inferred from 1emc 1ygj PROBYES 1 2 NPS C2 15985434 12235162 BU changed since last release and is now incorrect - Interface geometry conserved with 1ub0 (31%) - automaticaly inferred from 1lhr 1ygk PROBYES 1 2 NPS C2 15985434 12235162 BU changed since last release and is now incorrect - Interface geometry conserved with 1ub0 (31%) - automaticaly inferred from 1lhr 1ygp NO 2 2 C2 C2 8703213 8703213 INterface conserved with 1fa9 (50%) 1ygs NO 3 3 C3 C3 9214508 9214508 Interface geometry conserved with 1khx (42%) -- Annotation transfered from 1dd1 1yhj PROBYES 1 2 NPS C2 15985434 12235162 BU changed since last release and is now incorrect - Interface geometry conserved with 1ub0 (31%) - automaticaly inferred from 1lhr 1yik NO 1 1 NPS NPS 15701702 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1yil NO 1 1 NPS NPS 15701702 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1yja NO 1 1 NPS NPS 10048334 10048334 1yjb NO 1 1 NPS NPS 10048334 10048334 -- Annotation transfered from 1yja 1yjc NO 1 1 NPS NPS 10048334 10048334 -- Annotation transfered from 1yja 1yjs NO 2 2 C2 C2 15865438 11877399 Paper says the quaternary structure of bsSHMT is a dimer (gel filtration) - automatic transfer from 1kkp 1yjy NO 2 2 C2 C2 15865438 11877399 Paper says the quaternary structure of bsSHMT is a dimer (gel filtration) - automatic transfer from 1kkp 1yjz NO 2 2 C2 C2 15865438 11877399 Paper says the quaternary structure of bsSHMT is a dimer (gel filtration) - automatic transfer from 1kkp 1yk7 NO 1 1 NPS NPS 15780613 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 1yk8 NO 1 1 NPS NPS 15896958 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 1ykc NO 2 2 C2 C2 0 8182750 - automatic transfer from 1hna 1ykf NO 4 4 D2 D2 9836873 0 -- Annotation transfered from 1bxz 1ykr NO 1 1 NPS NPS 15780638 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 1ykx NO 1 1 NPS NPS 15983424 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1yky NO 1 1 NPS NPS 15983424 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1ykz NO 1 1 NPS NPS 15983424 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1yl0 NO 1 1 NPS NPS 15983424 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1yl1 NO 1 1 NPS NPS 15983424 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1ylv NO 8 8 D4 D4 10386874 10386874 Paper says octamer -- Annotation transfered from 1qml 1yma NO 1 1 NPS NPS 8175669 8175669 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1ymb NO 1 1 NPS NPS 2359126 2359126 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1ymc NO 1 1 NPS NPS 8197124 8197124 Myoglobin is well known to be monomeric -- Annotation transfered from 1gjn 1ymu YES 2 1 C2 NPS 8632450 8632450 CheY is a Mr 14,000 monomeric protein -- Annotation transfered from 1fqw 1ymv NO 1 1 NPS NPS 8632450 8632450 CheY is a Mr 14,000 monomeric protein -- Annotation transfered from 1chn 1yna PROBNOT 1 1 NPS NPS 9753433 9753433 1ynd_1 PROBNOT 1 1 NPS NPS 15772070 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1ynd_2 PROBNOT 1 1 NPS NPS 15772070 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1yno NO 4 4 D2 D2 0 9665697 Interface geometry conserved with 1ovm (25%) - automatic transfer from 1bfd 1ynu NO 2 2 C2 C2 15848188 12686108 - automatic transfer from 1m4n 1yog NO 1 1 NPS NPS 8810310 8810310 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1yoh NO 1 1 NPS NPS 8810310 8810310 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1yoi NO 1 1 NPS NPS 8810310 8810310 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 1yoo NO 2 2 C2 C2 9891001 9891001 1you_1 PROBNOT 1 1 NPS NPS 15780611 10074939 BU changed since last release and is now corrected - - automaticaly inferred from 456c 1you_2 PROBNOT 1 1 NPS NPS 15780611 10074939 BU changed since last release and is now corrected - - automaticaly inferred from 456c 1yp6 PROBNOT 1 1 NPS NPS 16104761 11316880 Gel filtration performed and no dimer or oligomer mentioned. - automatic transfer from 1i06 1yp7 PROBNOT 1 1 NPS NPS 16104761 11316880 Gel filtration performed and no dimer or oligomer mentioned. - automatic transfer from 1i06 1yp9 PROBNOT 1 1 NPS NPS 16374786 0 - automatic transfer from 1az8 1ypa NA 1 1 NPS NPS 8278384 8278384 - automatic transfer from 1ypc 1ypb NA 1 1 NPS NPS 8278384 8278384 - automatic transfer from 1ypc 1ypc NA 1 1 NPS NPS 8278384 8278384 1ypi NO 2 2 C2 C2 2204417 2204417 Interface geometry conserved with 1m6j (43%) -- Annotation transfered from 7tim 1ypp PROBNOT 2 2 C2 C2 8706712 8706712 SP says dimer -- Annotation transfered from 1wgi 1ypr_1 PROBNOT 1 1 NPS NPS 9698363 0 SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio - automatic transfer from 1k0k 1ypr_2 PROBNOT 1 1 NPS NPS 9698363 0 SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio - automatic transfer from 1k0k 1ypt PROBYES 2 1 C2 NPS 8052312 8052312 SP says monomer 1yqj PROBNOT 1 1 NPS NPS 15837335 11896401 - automatic transfer from 1kv1 1yqo_1 NA 1 1 NPS NPS 16403573 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1yqo_2 NA 1 1 NPS NPS 16403573 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1yqs PROBNOT 1 1 NPS NPS 15909988 15581896 the Streptomyces R61 and Actinomadura R39 DD-peptidases, are water-soluble monomeric proteins; (12723972) - automatic transfer from 1pwd 1yrc PROBNOT 1 1 NPS NPS 15858263 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1yrd PROBNOT 1 1 NPS NPS 15858263 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 1yrs_1 PROBNOT 1 1 NPS NPS 15808464 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 1yrs_2 PROBNOT 1 1 NPS NPS 15808464 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 1yry YES 1 3 NPS C3 16154528 14706628 Paper says trimer - automatic transfer from 1rct 1ysc PROBNOT 1 1 NPS NPS 7727362 7727362 Paper says: The structure of monomeric serine carboxypeptidase from Saccharomyces cerevisiae 1yso NO 2 2 C2 C2 8652572 8652572 SOD is a dimer -- Annotation transfered from 2jcw 1ysz NA 1 1 NPS NPS 15951571 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 1yt0 NA 1 1 NPS NPS 15951571 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 1yt1_1 NA 1 1 NPS NPS 15951571 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 1yt1_2 NA 1 1 NPS NPS 15951571 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 1yt2 NA 1 1 NPS NPS 15951571 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 1yt7 NO 1 1 NPS NPS 15982880 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 1yt9 NO 2 2 C2 C2 15837308 9083478 - automatic transfer from 1ajx 1ytb_1 PROBYES 1 2 NPS C2 8413604 8367480 BU changed since last release and is now incorrect - Interface geometry conserved with 1mp9 (46%) - automaticaly inferred from 1tbp 1ytb_2 PROBYES 1 2 NPS C2 8413604 8367480 BU changed since last release and is now incorrect - Interface geometry conserved with 1mp9 (46%) - automaticaly inferred from 1tbp 1ytc PROBNOT 1 1 NPS NPS 8639684 8639684 1ytg NO 2 2 C2 C2 8841139 8841139 -- Annotation transfered from 1ajx 1yth NO 2 2 C2 C2 8841139 8841139 -- Annotation transfered from 1ajx 1yti NO 2 2 C2 C2 8841139 8841139 -- Annotation transfered from 1az5 1ytj NO 2 2 C2 C2 8841139 8841139 -- Annotation transfered from 1az5 1ytn PROBNOT 1 1 NPS NPS 8702535 8702535 -- Annotation transfered from 1yts 1ytq PROBYES 1 2 NPS C2 0 12084052 BU changed since last release and is now incorrect - B2-crystallin is a dimer in solution -- very interesting review: about evolution of oligomers! - automaticaly inferred from 2bb2 1yts PROBNOT 1 1 NPS NPS 8528087 8528087 1ytt PROBNOT 2 2 C2 C2 8539602 8539602 Interface geometry conserved with 1rdk (>50%) - although the interface structure has changed. -- Annotation transfered from 1msb 1ytv PROBYES 2 1 C2 NPS 16511036 12794084 BU changed since last release and is now incorrect - EcoCyc says monomer - automaticaly inferred from 1nl5 1ytw PROBNOT 1 1 NPS NPS 8702535 8702535 -- Annotation transfered from 1yts 1yvh NA 1 1 NPS NPS 15737992 10078535 BU changed since last release and is now corrected - Paper does not mention a trimer - automaticaly inferred from 2cbl 1yvs YES 6 3 D3 C3 9927651 9927651 BU changed since last release and is now incorrect - Paper says trimer - domain swapped 1yw7 PROBNOT 1 1 NPS NPS 0 9812898 Paper says nothing, PISA says monomer - automatic transfer from 1b6a 1yw8 PROBNOT 1 1 NPS NPS 0 9812898 Paper says nothing, PISA says monomer - automatic transfer from 1b6a 1yw9 PROBNOT 1 1 NPS NPS 0 9812898 Paper says nothing, PISA says monomer - automatic transfer from 1b6a 1ywn PROBNOT 1 1 NPS NPS 15837294 10368301 - automatic transfer from 1vr2 1yx9 PROBYES 1 2 NPS C2 15883044 1418819 BU changed since last release and is now incorrect - They discuss the dimer in the paper. The enzyme is generally described as a monomer and I dont think this dimeric state is relevant as 2psg (99%) also forms a dimer but with a completely different config. - automaticaly inferred from 1psa 1yxc NO 4 4 D2 D2 16041077 15066435 Interface geometry conserved with 1fdy (25%) -- interesting QS evolution: interface geometry of these two proteins from e coli is conserved while the geometry with other proteins (closer in seq % id but from other organisms) is not. - automatic transfer from 1s5w 1yxd NO 4 4 D2 D2 16041077 15066435 Interface geometry conserved with 1fdy (25%) -- interesting QS evolution: interface geometry of these two proteins from e coli is conserved while the geometry with other proteins (closer in seq % id but from other organisms) is not. - automatic transfer from 1s5w 1yxl PROBNOT 1 1 NPS NPS 0 16301791 Paper says nothing about oligomer - PISA says monomer - automatic transfer from 1td7 1yxq PROBYES 2 1 C2 NPS 15797212 11474115 BU changed since last release and is now incorrect - Actin exists in different states - automaticaly inferred from 1j6z 1yyy PROBNOT 1 1 NPS NPS 9724521 9724521 -- Annotation transfered from 1az8 1yzn PROBNOT 1 1 NPS NPS 16034420 16034420 Paper suggests is it a monomer 1z07 PROBNOT 1 1 NPS NPS 16034420 11278565 - automatic transfer from 1huq 1z0d_1 PROBNOT 1 1 NPS NPS 16034420 11278565 - automatic transfer from 1huq 1z0d_2 PROBNOT 1 1 NPS NPS 16034420 11278565 - automatic transfer from 1huq 1z3l PROBNOT 1 1 NPS NPS 15823052 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1z3m PROBNOT 1 1 NPS NPS 15823052 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1z3n NA 1 1 NPS NPS 15857120 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 1z3p PROBNOT 1 1 NPS NPS 15823052 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1z3t PROBNOT 1 1 NPS NPS 15819888 11743726 Paper says: produce a dimer in the crystal. For the intact protein in vivo, a linker and CBM would be connected to the C terminus of the catalytic module, and additional sugar groups would be expected to be found at Asn286; both of these factors would be expected to interfere with the formation of a dimer in vivo. - automatic transfer from 1gpi 1z3v PROBNOT 1 1 NPS NPS 15819888 11743726 Paper says: produce a dimer in the crystal. For the intact protein in vivo, a linker and CBM would be connected to the C terminus of the catalytic module, and additional sugar groups would be expected to be found at Asn286; both of these factors would be expected to interfere with the formation of a dimer in vivo. - automatic transfer from 1gpi 1z3w PROBNOT 1 1 NPS NPS 15819888 11743726 Paper says: produce a dimer in the crystal. For the intact protein in vivo, a linker and CBM would be connected to the C terminus of the catalytic module, and additional sugar groups would be expected to be found at Asn286; both of these factors would be expected to interfere with the formation of a dimer in vivo. - automatic transfer from 1gpi 1z3z PROBYES 1 4 NPS D2 16342932 7947767 BU changed since last release and is now incorrect - Paper says tetramer - automaticaly inferred from 1dge 1z4i YES 2 1 C2 NPS 16004879 15044615 BU changed since last release and is now incorrect - PISA is right - automaticaly inferred from 1q91 1z4j YES 2 1 C2 NPS 16004879 15044615 BU changed since last release and is now incorrect - PISA is right - automaticaly inferred from 1q91 1z4k YES 2 1 C2 NPS 16004879 15044615 BU changed since last release and is now incorrect - PISA is right - automaticaly inferred from 1q91 1z4l YES 2 1 C2 NPS 16004879 15044615 BU changed since last release and is now incorrect - PISA is right - automaticaly inferred from 1q91 1z4m YES 2 1 C2 NPS 16004879 15044615 BU changed since last release and is now incorrect - PISA is right - automaticaly inferred from 1q91 1z4p YES 2 1 C2 NPS 16004879 15044615 BU changed since last release and is now incorrect - PISA is right - automaticaly inferred from 1q91 1z4q YES 2 1 C2 NPS 16004879 15044615 BU changed since last release and is now incorrect - PISA is right - automaticaly inferred from 1q91 1z53 PROBNOT 1 1 NPS NPS 15900441 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 1z55 NO 1 1 NPS NPS 15983424 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1z5m NO 1 1 NPS NPS 15772071 15209375 gel filtration studies suggest that PDK1 is monomeric - automatic transfer from 1okz 1z5p NO 2 2 C2 C2 16109423 12496243 Paper implies dimer - Dimer conserved with the dimer of the related hexameric form - automatic transfer from 1nc3 1z62 PROBYES 2 2 C2 C2 -1 9384557 Wrong interface of the dimer - automatic transfer from 2amv 1z6d_1 PROBNOT 1 1 NPS NPS 16045769 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1z6d_2 PROBNOT 1 1 NPS NPS 16045769 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1z6p PROBYES 2 2 C2 C2 15214781 9384557 Wrong interface of the dimer - automatic transfer from 2amv 1z6q PROBYES 2 2 C2 C2 15214781 9384557 Wrong interface of the dimer - automatic transfer from 2amv 1z6s_1 PROBNOT 1 1 NPS NPS 16045769 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1z6s_2 PROBNOT 1 1 NPS NPS 16045769 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 1z71 PROBNOT 1 1 NPS NPS 15911253 11053836 - automatic transfer from 1doj 1z7g_1 NO 4 4 D2 D2 15990111 10360366 Tetramer, interface conserved down to 40% (1fsg). - automatic transfer from 1bzy 1z7g_2 NO 4 4 D2 D2 15990111 10360366 Tetramer, interface conserved down to 40% (1fsg). - automatic transfer from 1bzy 1z7j NO 4 4 D2 D2 16204882 11106758 - automatic transfer from 1g1o 1z89 NA 1 1 NPS NPS 16337231 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 1z8a NA 1 1 NPS NPS 16337231 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 1z8o PROBNOT 1 1 NPS NPS 15824115 10716705 Paper does not mention oligomer - PISA says monomer - many instances of monomers - automatic transfer from 1egy 1z8p PROBNOT 1 1 NPS NPS 15824115 10716705 Paper does not mention oligomer - PISA says monomer - many instances of monomers - automatic transfer from 1egy 1z9y PROBNOT 1 1 NPS NPS 0 8987974 9000633 says monomeric - automatic transfer from 1uga 1za5 NO 2 2 C2 C2 16430211 7849024 Paper says dimer - automatic transfer from 1isc 1zak PROBYES 2 1 C2 NPS 9428681 9428681 homologous protein are monomers and that PISA says monomer - stil not sure 1zap PROBNOT 1 1 NPS NPS 8845753 8591036 BU changed since last release and is now corrected - Paper implies it is monomeric: Assignments were in agreement typical of the monomeric aspartic-proteinase family. -- good example of large crystal contact - automaticaly inferred from 1eag 1zbv NO 1 1 NPS NPS 0 12529329 Elutes as a monomer - Papers says: The second peak in this final chromatographic step corresponded to a molecular mass of 40 kDa. - automatic transfer from 1ljy 1zbw NO 1 1 NPS NPS 0 12529329 Elutes as a monomer - Papers says: The second peak in this final chromatographic step corresponded to a molecular mass of 40 kDa. - automatic transfer from 1ljy 1zbx PROBNOT 2 2 NPS NPS 15937111 15937111 Paper indicates this structure 1zby PROBNOT 1 1 NPS NPS 12741816 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 1zbz PROBNOT 1 1 NPS NPS 12741816 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 1zc9 PROBYES 1 4 NPS D2 16342932 7947767 BU changed since last release and is now incorrect - Paper says tetramer - automaticaly inferred from 1dge 1zcr NO 4 4 D2 D2 15981995 11106758 - automatic transfer from 1g1o 1zd6 NO 4 4 D2 D2 15981995 11106758 - automatic transfer from 1g1o 1zdm_1 PROBNOT 1 1 NPS NPS 15741343 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 1zdm_2 PROBNOT 1 1 NPS NPS 15741343 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 1zdq NO 3 3 C3 C3 16574144 9353305 - automatic transfer from 1as7 1zds NO 3 3 C3 C3 16574144 9353305 - automatic transfer from 1as7 1ze8 PROBNOT 1 1 NPS NPS 16134940 8987974 9000633 says monomeric - automatic transfer from 1uga 1zei PROBNOT 6 6 D3 D3 9708987 9708987 Paper says hexamer 1zen NO 2 2 C2 C2 8939754 8939754 -- Annotation transfered from 1b57 1zeo PROBNOT 2 2 C2 C2 15974597 15258145 BU changed since last release and is now corrected - PISA says homodimer and identicals are homodimers - automaticaly inferred from 1wm0 1zfk PROBNOT 1 1 NPS NPS 0 8987974 9000633 says monomeric - automatic transfer from 1uga 1zfp NO 1 1 NPS NPS 9642078 9642078 1zfq PROBNOT 1 1 NPS NPS 0 8987974 9000633 says monomeric - automatic transfer from 1uga 1zg4 PROBNOT 1 1 NPS NPS 16041072 12079336 EcoCyc says monomer - automatic transfer from 1jwp 1zgb PROBYES 2 4 NS NA 16076210 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 1zgc PROBYES 2 4 C2 NA 16076210 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 1zge PROBNOT 1 1 NPS NPS 0 8987974 9000633 says monomeric - automatic transfer from 1uga 1zgf PROBNOT 1 1 NPS NPS 0 8987974 9000633 says monomeric - automatic transfer from 1uga 1zgi PROBNOT 1 1 NPS NPS 16137886 11053836 - automatic transfer from 1doj 1zgn NO 2 2 C2 C2 16195232 9398518 - automatic transfer from 9gss 1zgv PROBNOT 1 1 NPS NPS 16137886 11053836 - automatic transfer from 1doj 1zgy PROBYES 1 2 NPS C2 15976031 15258145 PISA says homodimer and identicals are homodimers - automatic transfer from 1wm0 1zhi PROBNOT 2 2 NPS NPS 15932939 15937111 Paper indicates this structure -- Annotation transfered from 1zbx 1zia NO 1 1 NPS NPS 8138527 8138527 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 1zib NO 1 1 NPS NPS 8138527 8138527 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 -- Annotation transfered from 1zia 1zid NO 4 4 D2 D2 9417034 9417034 1zii NO 2 2 C2 C2 8946853 8946853 Paper says dimer -- Annotation transfered from 1zil 1zij NO 3 3 C3 C3 8946853 8946853 Paper says trimer - Engineered Leucine Zipper protein GCN4 1zik NO 2 2 C2 C2 8946854 8946854 Paper says dimer -- Annotation transfered from 1zil 1zil NO 2 2 C2 C2 8946854 8946854 Paper says dimer 1zim NO 3 3 C3 C3 8946854 8946854 Paper says trimer - Engineered Leucine Zipper protein GCN4 -- Annotation transfered from 1zij 1zin PROBNOT 1 1 NPS NPS 9715904 9715904 SP says monomer 1zio PROBNOT 1 1 NPS NPS 9715904 9715904 SP says monomer -- Annotation transfered from 1zin 1zip PROBNOT 1 1 NPS NPS 9715904 9715904 SP says monomer -- Annotation transfered from 1zin 1ziu PROBNOT 1 1 NPS NPS 16288781 12794084 EcoCyc says monomer - automatic transfer from 1nl5 1zjl PROBNOT 1 1 NPS NPS 16288781 12794084 EcoCyc says monomer - automatic transfer from 1nl5 1zjy NO 4 4 D2 D2 15896805 12628239 paper says tetramer - automatic transfer from 1nxq 1zk1 NO 4 4 D2 D2 15896805 12628239 paper says tetramer - automatic transfer from 1nxq 1zk2 NO 4 4 D2 D2 15896805 12628239 paper says tetramer - automatic transfer from 1nxq 1zk3_1 NO 4 4 D2 D2 15896805 12628239 paper says tetramer - automatic transfer from 1nxq 1zk3_2 NO 4 4 D2 D2 15896805 12628239 paper says tetramer - automatic transfer from 1nxq 1zk4 NO 4 4 D2 D2 15896805 12628239 paper says tetramer - automatic transfer from 1nxq 1zkb PROBNOT 1 1 NPS NPS 16288781 12794084 EcoCyc says monomer - automatic transfer from 1nl5 1zkf_1 PROBNOT 1 1 NPS NPS 0 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1zkf_2 PROBNOT 1 1 NPS NPS 0 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 1zkn PROBNOT 4 4 D2 D2 14668322 12842049 the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automatic transfer from 1oyn 1zkr PROBYES 2 1 NS NPS 0 12851385 Paper says: Herein, we report the crystal structure of recombinant monomeric Fel d 1 at 1.85-A resolution - automatic transfer from 1puo 1zl7 NA 1 1 NPS NPS 16376474 0 - automatic transfer from 1umv 1zlb NA 1 1 NPS NPS 16376474 0 - automatic transfer from 1umv 1zlt PROBNOT 1 1 NPS NPS 0 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 1zlx NO 1 1 NPS NPS 16026156 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1zly NO 1 1 NPS NPS 16026156 12450384 Paper says: Human GAR Tfase remains monomeric in the crystals at both pH 8.5 (hgar) and pH 4.2 (lgar). The human protein is also monomeric at pH 5 and 8 in solution, as confirmed by size exclusion chromatography -- This paper is very interesting as it summarizes the litterature for the E. coli protein - automatic transfer from 1meo 1zlz NO 2 2 C2 C2 0 11294629 PAper, SP say dimer - automatic transfer from 1i0h 1zm6 PROBNOT 1 1 NPS NPS 16278156 16301791 Paper says nothing about oligomer - PISA says monomer - automatic transfer from 1td7 1zmg PROBNOT 1 1 NPS NPS 16288781 12794084 EcoCyc says monomer - automatic transfer from 1nl5 1zmt NO 4 4 D2 D2 16173767 14517233 Interface geometry conserved with 1o5i (29%) -- interesting class to show burst of crosstalk below 30% - automatic transfer from 1pwx 1zmy_2 NO 1 1 NPS NPS 16095608 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 1znb_1 PROBNOT 1 1 NPS NPS 8805566 9730812 BU changed since last release and is now corrected - - automaticaly inferred from 1a7t 1znb_2 PROBNOT 1 1 NPS NPS 8805566 9730812 BU changed since last release and is now corrected - - automaticaly inferred from 1a7t 1znd PROBNOT 1 1 NPS NPS 16316253 11316880 Gel filtration performed and no dimer or oligomer mentioned. - automatic transfer from 1i06 1zne PROBNOT 1 1 NPS NPS 16316253 11316880 Gel filtration performed and no dimer or oligomer mentioned. - automatic transfer from 1i06 1zng PROBNOT 1 1 NPS NPS 16316253 11316880 Gel filtration performed and no dimer or oligomer mentioned. - automatic transfer from 1i06 1znh PROBNOT 1 1 NPS NPS 16316253 11316880 Gel filtration performed and no dimer or oligomer mentioned. - automatic transfer from 1i06 1znk PROBNOT 1 1 NPS NPS 16316253 11316880 Gel filtration performed and no dimer or oligomer mentioned. - automatic transfer from 1i06 1znl PROBNOT 1 1 NPS NPS 16316253 11316880 Gel filtration performed and no dimer or oligomer mentioned. - automatic transfer from 1i06 1znw PROBNOT 1 1 NPS NPS 16288457 0 No paper, PISA says monomer - automatic transfer from 1s4q 1znx PROBNOT 1 1 NPS NPS 16288457 0 No paper, PISA says monomer - automatic transfer from 1s4q 1zny PROBNOT 1 1 NPS NPS 16288457 0 No paper, PISA says monomer - automatic transfer from 1s4q 1znz PROBNOT 1 1 NPS NPS 16288457 0 No paper, PISA says monomer - automatic transfer from 1s4q 1zo8_1 NO 4 4 D2 D2 16173767 14517233 Interface geometry conserved with 1o5i (29%) -- interesting class to show burst of crosstalk below 30% - automatic transfer from 1pwx 1zo8_2 NO 4 4 D2 D2 16173767 14517233 Interface geometry conserved with 1o5i (29%) -- interesting class to show burst of crosstalk below 30% - automatic transfer from 1pwx 1zo8_3 NO 4 4 D2 D2 16173767 14517233 Interface geometry conserved with 1o5i (29%) -- interesting class to show burst of crosstalk below 30% - automatic transfer from 1pwx 1zo8_4 NO 4 4 D2 D2 16173767 14517233 Interface geometry conserved with 1o5i (29%) -- interesting class to show burst of crosstalk below 30% - automatic transfer from 1pwx 1zo8_5 NO 4 4 D2 D2 16173767 14517233 Interface geometry conserved with 1o5i (29%) -- interesting class to show burst of crosstalk below 30% - automatic transfer from 1pwx 1zo9_1 NA 1 1 NPS NPS 0 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1zo9_2 NA 1 1 NPS NPS 0 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 1zob PROBYES 1 4 NPS D2 0 7947767 BU changed since last release and is now incorrect - Paper says tetramer - automaticaly inferred from 1dge 1zod PROBYES 1 4 NPS D2 0 7947767 BU changed since last release and is now incorrect - Paper says tetramer - automaticaly inferred from 1dge 1zoe PROBYES 2 1 C2 NPS 16298300 11604527 BU changed since last release and is now incorrect - Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. - automaticaly inferred from 1jam 1zog PROBYES 2 1 C2 NPS 16298300 11604527 BU changed since last release and is now incorrect - Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. - automaticaly inferred from 1jam 1zoh PROBYES 2 1 C2 NPS 16298300 11604527 BU changed since last release and is now incorrect - Protein kinase CK2 is a tetrameric enzyme comprised of two regulatory subunits (CK2b) and two catalytic subunits (CK2a andor CK2aprime). The crystal structure of dimeric CK2b demonstrated that a zinc finger mediates CK2b. The two catalytic subs do not contact each other. - automaticaly inferred from 1jam 1zon PROBNOT 1 1 NPS NPS 8805579 8805579 1zoo PROBNOT 2 2 C2 C2 8805579 8805579 Gel filtration chromatography reveals that, in the presence of Mn2+, the CD11a I domain exists in an equilibrium between monomer and dimer in solution - interesting 1zop PROBNOT 2 2 C2 C2 8805579 8805579 Gel filtration chromatography reveals that, in the presence of Mn2+, the CD11a I domain exists in an equilibrium between monomer and dimer in solution - interesting -- Annotation transfered from 1zoo 1zp5 PROBNOT 1 1 NPS NPS 16242329 9655333 No clear evidence after a quick search but PISA agrees ... - automatic transfer from 1a85 1zp8 NO 2 2 C2 C2 15934050 9083478 - automatic transfer from 1ajx 1zpa NO 2 2 C2 C2 15934050 9083478 - automatic transfer from 1ajx 1zpd NO 4 4 D2 D2 9685367 9685367 Interface geometry conserved with 1ovm (31%) 1zpe_1 PROBYES 1 3 NPS C3 16266687 11278703 BU changed since last release and is now incorrect - Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automaticaly inferred from 1hqx 1zpe_2 PROBYES 1 3 NPS C3 16266687 11278703 BU changed since last release and is now incorrect - Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automaticaly inferred from 1hqx 1zpe_3 PROBYES 1 3 NPS C3 16266687 11278703 BU changed since last release and is now incorrect - Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automaticaly inferred from 1hqx 1zpg_1 PROBYES 1 3 NPS C3 16266687 11278703 BU changed since last release and is now incorrect - Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automaticaly inferred from 1hqx 1zpg_2 PROBYES 1 3 NPS C3 16266687 11278703 BU changed since last release and is now incorrect - Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automaticaly inferred from 1hqx 1zpg_3 PROBYES 1 3 NPS C3 16266687 11278703 BU changed since last release and is now incorrect - Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference - automaticaly inferred from 1hqx 1zpr NO 2 2 C2 C2 8973201 8973201 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 1zq5 PROBNOT 1 1 NPS NPS 0 14996743 PISA says it is a monomer, and relative are too. - automatic transfer from 1s1r 1zr8 PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 1zrb PROBNOT 1 1 NPS NPS 15801822 11053836 - automatic transfer from 1doj 1zs0 PROBNOT 1 1 NPS NPS 16451058 9655333 No clear evidence after a quick search but PISA agrees ... - automatic transfer from 1a85 1zs2 NO 1 1 NPS NPS -1 12364331 9882648 says: Under both native and denaturing conditions, the molecular mass obtained was 70 ± 2 kDa (Fig. 3B). This result demonstrates the monomeric structure of the amylosucrase from N. polysaccharea - automatic transfer from 1mw1 1zsa PROBNOT 1 1 NPS NPS 8639494 8639494 9000633 says monomeric -- Annotation transfered from 1uga 1zsb PROBNOT 1 1 NPS NPS 8639494 8639494 9000633 says monomeric -- Annotation transfered from 1uga 1zsc PROBNOT 1 1 NPS NPS 8639494 8639494 9000633 says monomeric -- Annotation transfered from 1uga 1zsf NO 2 2 C2 C2 16627941 9083478 - automatic transfer from 1ajx 1zsn NO 4 4 D2 D2 16198563 0 - automatic transfer from 1v35 1zsp NO 4 4 D2 D2 0 1394426 Paper says tetramer - automatic transfer from 1n0j 1zsq PROBNOT 1 1 NPS NPS 16410353 14690594 BU changed since last release and is now corrected - Was shown to form dimers but via the coiled coil region (12668758) which is not in the crystal structure - automaticaly inferred from 1m7r 1zsr YES 2 1 C2 NPS 16627941 7664084 BU changed since last release and is now incorrect - SCOP error, only one domain is defined but there are two that are fused. - automaticaly inferred from 1hvc 1zt9_1 NO 2 2 C2 C2 0 0 - automatic transfer from 1jhg 1zt9_2 NO 2 2 C2 C2 0 0 - automatic transfer from 1jhg 1zte NO 4 4 D2 D2 0 1394426 Paper says tetramer - automatic transfer from 1n0j 1ztq_1 PROBNOT 1 1 NPS NPS 16005220 10074939 BU changed since last release and is now corrected - - automaticaly inferred from 456c 1ztq_2 PROBNOT 1 1 NPS NPS 16005220 10074939 BU changed since last release and is now corrected - - automaticaly inferred from 456c 1ztq_3 PROBNOT 1 1 NPS NPS 16005220 10074939 BU changed since last release and is now corrected - - automaticaly inferred from 456c 1ztq_4 PROBNOT 1 1 NPS NPS 16005220 10074939 BU changed since last release and is now corrected - - automaticaly inferred from 456c 1ztt PROBYES 2 1 C2 NPS 16049022 10669612 BU changed since last release and is now incorrect - - automatic transfer from 1qai 1ztw PROBYES 2 1 C2 NPS 16049022 10669612 BU changed since last release and is now incorrect - - automatic transfer from 1qai 1ztz PROBNOT 2 2 C2 C2 16227435 10651036 BU changed since last release and is now corrected - - automaticaly inferred from 3tlh 1zu8 NO 1 1 NPS NPS 0 12529329 Elutes as a monomer - Papers says: The second peak in this final chromatographic step corresponded to a molecular mass of 40 kDa. - automatic transfer from 1ljy 1zuc PROBNOT 2 2 C2 C2 15937332 15189034 no info in paper, PISA says dimer - automatic transfer from 1sr7 1zuq NO 4 4 D2 D2 0 1394426 Paper says tetramer - automatic transfer from 1n0j 1zur NO 1 1 NPS NPS 0 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1zv2 NO 3 3 C3 C3 16131751 0 - automatic transfer from 1n70 1zvi NO 2 2 C2 C2 16033258 12437343 Clear dimer - automatic transfer from 1m00 1zvl NO 2 2 C2 C2 16033258 12437343 Clear dimer - automatic transfer from 1m00 1zvq NO 1 1 NPS NPS 16531227 10574788 Ras proteins are monomeric G proteins - automatic transfer from 1ctq 1zvr PROBNOT 1 1 NPS NPS 16410353 14690594 BU changed since last release and is now corrected - Was shown to form dimers but via the coiled coil region (12668758) which is not in the crystal structure - automaticaly inferred from 1m7r 1zvx PROBNOT 1 1 NPS NPS 16451058 9655333 No clear evidence after a quick search but PISA agrees ... - automatic transfer from 1a85 1zw1 NO 4 4 D2 D2 16198563 0 - automatic transfer from 1v35 1zw6 NO 1 1 NPS NPS 16531227 10574788 Ras proteins are monomeric G proteins - automatic transfer from 1ctq 1zwn NO 1 1 NPS NPS 0 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 1zwp PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 1zx1 NO 2 2 C2 C2 0 10433694 - automatic transfer from 1qr2 1zxb NO 4 4 D2 D2 16198563 0 - automatic transfer from 1v35 1zxl NO 4 4 D2 D2 16198563 0 - automatic transfer from 1v35 1zxq PROBYES 2 1 C2 NPS 9153399 7608533 Paper show that ICAM-1 is dimeric but not this one (ICAM-2) 1zxv_1 PROBNOT 1 1 NPS NPS 15983377 11700563 Paper says nothing about a dimer - an email was sent to the authors -- And its a nature paper!!!! CRAP - automatic transfer from 1jky 1zxv_2 PROBNOT 1 1 NPS NPS 15983377 11700563 Paper says nothing about a dimer - an email was sent to the authors -- And its a nature paper!!!! CRAP - automatic transfer from 1jky 1zyj PROBNOT 1 1 NPS NPS 16169718 11896401 - automatic transfer from 1kv1 1zyu PROBNOT 1 1 NPS NPS 16834327 12054870 SP says monomer - automatic transfer from 1l4u 1zyx PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 1zz2 PROBNOT 1 1 NPS NPS 16169718 11896401 - automatic transfer from 1kv1 1zzl PROBNOT 1 1 NPS NPS 16134941 11896401 - automatic transfer from 1kv1 1zzq NO 2 2 C2 C2 16285725 12437343 Clear dimer - automatic transfer from 1m00 1zzs NO 2 2 C2 C2 16285725 11331003 Clear dimer - automatic transfer from 1fol 1zzz PROBNOT 1 1 NPS NPS 9724521 9724521 -- Annotation transfered from 1az8 200l NO 1 1 NPS NPS 8676387 8676387 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 201l_1 PROBNOT 1 1 NPS NPS 8429913 8503008 BU changed since last release and is now corrected - Phage T4 Lysosyme is monomeric - automaticaly inferred from 137l 201l_2 PROBNOT 1 1 NPS NPS 8429913 8503008 BU changed since last release and is now corrected - Phage T4 Lysosyme is monomeric - automaticaly inferred from 137l 205l NO 1 1 NPS NPS 8429913 8429913 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 206l NO 1 1 NPS NPS 8218201 8218201 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 207l NO 1 1 NPS NPS 8902616 8902616 Lysozyme C is monomeric -- Annotation transfered from 1lzr 208l NO 1 1 NPS NPS 8902616 8902616 Lysozyme C is monomeric -- Annotation transfered from 1lzr 209l NO 1 1 NPS NPS 8976549 8976549 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 20gs NO 2 2 C2 C2 10452896 0 -- Annotation transfered from 9gss 210l NO 1 1 NPS NPS 8976549 8976549 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 211l NO 1 1 NPS NPS 8976549 8976549 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 212l NO 1 1 NPS NPS 8976549 8976549 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 213l NO 1 1 NPS NPS 8976549 8976549 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 214l NO 1 1 NPS NPS 8976549 8976549 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 215l NO 1 1 NPS NPS 8976549 8976549 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 216l_1 NO 1 1 NPS NPS 8503008 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 216l_2 NO 1 1 NPS NPS 8503008 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 217l NO 1 1 NPS NPS 8503008 8503008 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 218l NO 1 1 NPS NPS 8976549 8976549 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 219l NO 1 1 NPS NPS 8976549 8976549 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 21bi PROBNOT 1 1 NPS NPS 0 0 SP says monomer 21gs NO 2 2 C2 C2 0 0 -- Annotation transfered from 9gss 220l NO 1 1 NPS NPS 9514755 9514755 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 221l NO 1 1 NPS NPS 8218201 8218201 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 221p PROBYES 2 1 C2 NPS 2199064 2199064 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 222l NO 1 1 NPS NPS 9514755 9514755 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 223l NO 1 1 NPS NPS 9514755 9514755 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 224l NO 1 1 NPS NPS 8218201 8218201 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 225l NO 1 1 NPS NPS 9514755 9514755 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 226l NO 1 1 NPS NPS 9514755 9514755 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 227l NO 1 1 NPS NPS 9514755 9514755 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 228l NO 1 1 NPS NPS 9514755 9514755 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 229l NO 1 1 NPS NPS 9514755 9514755 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 22gs NO 2 2 C2 C2 0 0 -- Annotation transfered from 9gss 230l NO 1 1 NPS NPS 9541409 9541409 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 231l NO 1 1 NPS NPS 9541409 9541409 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 232l NO 1 1 NPS NPS 9541409 9541409 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 233l NO 1 1 NPS NPS 9541409 9541409 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 234l NO 1 1 NPS NPS 9541409 9541409 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 235l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 236l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 237l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 238l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 239l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 240l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 241l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 242l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 243l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 244l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 245l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 246l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 247l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 248l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 249l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 250l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 251l NO 1 1 NPS NPS 9514271 9514271 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 252l NO 1 1 NPS NPS 9514755 9514755 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 253l NO 1 1 NPS NPS 7831309 7831309 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 254l NO 1 1 NPS NPS 7831309 7831309 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 255l NO 1 1 NPS NPS 7831309 7831309 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 256b PROBYES 2 1 C2 NPS 7031264 7031264 SP, EcoCyc, PISA say monomer -- Annotation transfered from 1lm3 256l NO 1 1 NPS NPS 2234094 2234094 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 257l NO 1 1 NPS NPS 10835104 10835104 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 258l NO 1 1 NPS NPS 10835104 10835104 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 259l NO 1 1 NPS NPS 10835104 10835104 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 260l NO 1 1 NPS NPS 10835104 10835104 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 261l NO 1 1 NPS NPS 10339544 10339544 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 2a0c NO 1 1 NPS NPS 16003486 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2a0n PROBNOT 1 1 NPS NPS 0 10968789 BU changed since last release and is now corrected - The HisH and HisF proteins form a stable 1 : 1 dimeric complex that constitutes the IGP synthase holoenzyme. - automaticaly inferred from 1thf 2a1h NO 2 2 C2 C2 0 12269802 Paper says dimer: The mammalian BCATs are homodimers with molecular masses ranging from about 41000 to 46000. - SP too - automatic transfer from 1kta 2a1m_1 PROBNOT 1 1 NPS NPS 15994329 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 2a1m_2 PROBNOT 1 1 NPS NPS 15994329 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 2a21 NO 4 4 D2 D2 0 11115499 Paper says tetramer - automatic transfer from 1fws 2a2g PROBYES 4 2 D2 C2 10089305 10089305 8761444 says dimer -- Annotation transfered from 2a2u 2a2i NO 4 4 D2 D2 0 11115499 Paper says tetramer - automatic transfer from 1fws 2a2r NO 2 2 C2 C2 16597834 9398518 - automatic transfer from 9gss 2a2s NO 2 2 C2 C2 16597834 9398518 - automatic transfer from 9gss 2a2u PROBYES 4 2 D2 C2 10089305 10089305 8761444 says dimer 2a31 PROBNOT 1 1 NPS NPS 16536459 10561533 - automatic transfer from 1qqu 2a32 PROBNOT 1 1 NPS NPS 16536459 10561533 - automatic transfer from 1qqu 2a39_1 PROBNOT 1 1 NPS NPS 9761741 9335168 SP says monomer - automatic transfer from 1a39 2a39_2 PROBNOT 1 1 NPS NPS 9761741 9335168 SP says monomer - automatic transfer from 1a39 2a3r_1 PROBNOT 1 1 NPS NPS 16083857 10543947 Paper says nothing, PISA says monomer - automatic transfer from 1cjm 2a3r_2 PROBNOT 1 1 NPS NPS 16083857 10543947 Paper says nothing, PISA says monomer - automatic transfer from 1cjm 2a3t NO 3 3 C3 C3 16131751 0 - automatic transfer from 1n70 2a3u PROBNOT 1 1 NPS NPS 16055923 14609325 - automatic transfer from 1ong 2a49 PROBNOT 1 1 NPS NPS 16055923 14609325 - automatic transfer from 1ong 2a4f NO 2 2 C2 C2 16203141 9083478 - automatic transfer from 1ajx 2a4l NO 1 1 NPS NPS 9030780 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2a4n PROBNOT 2 2 C2 C2 16131761 10378269 BU changed since last release and is now corrected - 1bo4 (33% id) has similar domain geometry - automaticaly inferred from 1b87 2a4t NO 1 1 NPS NPS 0 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2a4w YES 2 2 C2 C2 16756991 12121648 Paper says: In all three crystal structures, a single monomer occupies the asymmetric unit of the C2 unit cell, and two monomers form a close association with the resultant 2-fold axis of the MRD dimer corresponding to the crystallographic dyad. This is consistent with our gel filtration results (data not shown), which indicate that a dimer is the predominant species in solution. - domain swapped dimer -- wrong interface - automatic transfer from 1kll 2a4x YES 2 2 C2 C2 16756991 12121648 Paper says: In all three crystal structures, a single monomer occupies the asymmetric unit of the C2 unit cell, and two monomers form a close association with the resultant 2-fold axis of the MRD dimer corresponding to the crystallographic dyad. This is consistent with our gel filtration results (data not shown), which indicate that a dimer is the predominant species in solution. - domain swapped dimer -- wrong interface - automatic transfer from 1kll 2a5x YES 2 1 C2 NPS 16141336 11932258 Actin does not form closed dimer - automatic transfer from 1lcu 2a6l NO 4 4 D2 D2 16185069 15066435 Interface geometry conserved with 1fdy (25%) -- interesting QS evolution: interface geometry of these two proteins from e coli is conserved while the geometry with other proteins (closer in seq % id but from other organisms) is not. - automatic transfer from 1s5w 2a6n NO 4 4 D2 D2 16185069 15066435 Interface geometry conserved with 1fdy (25%) -- interesting QS evolution: interface geometry of these two proteins from e coli is conserved while the geometry with other proteins (closer in seq % id but from other organisms) is not. - automatic transfer from 1s5w 2a7a YES 1 4 NPS D2 16131760 0 BU changed since last release and is now incorrect - - automaticaly inferred from 1qgl 2a7b NO 1 1 NPS NPS 16131760 12176391 BU changed since last release and is now corrected - AP1 is tetrameric, this is one domain of one subunit which shoichiometry in the complex is one. - automatic transfer from 1gyw_2 2a7c PROBNOT 1 1 NPS NPS 16131760 9443341 - automatic transfer from 1c1m 2a7d NO 1 1 NPS NPS 16131760 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2a7f NO 1 1 NPS NPS 16131760 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2a7h PROBNOT 1 1 NPS NPS 16131760 0 - automatic transfer from 1az8 2a7i PROBNOT 1 1 NPS NPS 16131760 10504569 BU changed since last release and is now corrected - Thaumatin is a stable monomeric protein of 22kDa - automaticaly inferred from 1thw 2a7j PROBNOT 1 1 NPS NPS 16131760 9443341 - automatic transfer from 1c1m 2a94 NO 4 4 D2 D2 16331982 15117937 BU changed since last release and is now corrected - SP says tetramer - automatic transfer from 1t25 2a9e NO 4 4 D2 D2 0 15023060 Interface geometry conserved with 1mqf (60% id) -- interesting for folding (renaturation experiment) - automatic transfer from 1qwm 2a9j NO 2 2 C2 C2 17052986 15258155 11038361 and SP say dimer - automatic transfer from 1t8p 2a9o PROBYES 1 2 NPS C2 0 15090529 BU changed since last release and is now incorrect - When a protein solution of 1 to 2 mg/ml was used, the technique revealed the presence of a monomeric species alone, while using solutions of 5 to 10 mg/ml we observed a dimeric species. Higher concentrations revealed an equilibrium between dimeric, tetrameric, and octameric forms. - careful: different dimers use different faces - interesting - automaticaly inferred from 1nxw 2a9p PROBYES 1 2 NPS C2 0 15090529 BU changed since last release and is now incorrect - When a protein solution of 1 to 2 mg/ml was used, the technique revealed the presence of a monomeric species alone, while using solutions of 5 to 10 mg/ml we observed a dimeric species. Higher concentrations revealed an equilibrium between dimeric, tetrameric, and octameric forms. - careful: different dimers use different faces - interesting - automaticaly inferred from 1nxw 2a9q PROBYES 1 2 NPS C2 0 15090529 BU changed since last release and is now incorrect - When a protein solution of 1 to 2 mg/ml was used, the technique revealed the presence of a monomeric species alone, while using solutions of 5 to 10 mg/ml we observed a dimeric species. Higher concentrations revealed an equilibrium between dimeric, tetrameric, and octameric forms. - careful: different dimers use different faces - interesting - automaticaly inferred from 1nxw 2a9w_1 PROBNOT 2 2 C2 C2 16204883 10648646 BU changed since last release and is now corrected - Clear dimer - automaticaly inferred from 1qqq 2a9w_2 PROBNOT 2 2 C2 C2 16204883 10648646 BU changed since last release and is now corrected - Clear dimer - automaticaly inferred from 1qqq 2aa9 PROBNOT 1 1 NPS NPS 16225867 13129913 SP says monomer - automatic transfer from 1q36 2aaa PROBNOT 1 1 NPS NPS 2207069 2207069 SP says monomer 2aak PROBNOT 1 1 NPS NPS 1321826 1321826 Paper says nothing, PISA says monomer -- monomeric state seems consistent across the different homologous proteins. 2aat NO 2 2 C2 C2 2513875 2513875 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 2aaw PROBNOT 2 2 C2 C2 16385005 0 BU changed since last release and is now corrected - Paper says it is a dimer - automatic transfer from 1okt 2aay PROBNOT 1 1 NPS NPS 16225867 13129913 SP says monomer - automatic transfer from 1q36 2ab6_1 NO 2 2 C2 C2 0 8182750 - automatic transfer from 1hna 2ab6_2 NO 2 2 C2 C2 0 8182750 - automatic transfer from 1hna 2aba NO 1 1 NPS NPS 16156787 0 PETN reductase is a monomeric flavoenzyme - automatic transfer from 1gvo 2abb NO 1 1 NPS NPS 16156787 0 PETN reductase is a monomeric flavoenzyme - automatic transfer from 1gvo 2abe PROBNOT 1 1 NPS NPS 16214338 8987974 9000633 says monomeric - automatic transfer from 1uga 2abx NA 2 2 C2 C2 3507686 1550821 Interface conserved with 1kba but alpha toxins are generally considered monomeric and kappa dimeric (9116014). However, in paper 2036359 it reads: In addition to these sequence differences, nBgt (this protein) and other neuronal a-neurotoxins can exist as dimers in solution (unlike most other long a-neurotoxins, which are monomers in solution), which may also be related to their physiological activity (Chiappinelli & Lee, 1985) -- This is clearly an ambiguous case. 2ac0 NA 4 4 C2 C2 16793544 8023157 BU changed since last release and is now corrected - I am not sure about that one. 9628871 shows a cartoon of how it bind. Normally, there are 2 palindromic sequences, but in the crystal structure there are only 3 proteins, and the binding mode seems not compatible with that shown in 9628871 - automaticaly inferred from 1tsr 2ace PROBNOT 1 1 NPS NPS 8989325 8989325 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 2acg PROBNOT 1 1 NPS NPS 8078936 8078936 SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio 2ack PROBNOT 1 1 NPS NPS 10089512 10089512 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an exmaple. -- Annotation transfered from 1acj 2acq NO 1 1 NPS NPS 8117658 8117658 SwissProt and PISA say monomer -- Annotation transfered from 1ads 2acr NO 1 1 NPS NPS 8117658 8117658 SwissProt and PISA say monomer -- Annotation transfered from 1ads 2acs NO 1 1 NPS NPS 8117658 8117658 SwissProt and PISA say monomer -- Annotation transfered from 1ads 2act PROBNOT 1 1 NPS NPS -1 0 related proteins are monomeric and PISA says monomer -- example for illustrating a case where I am not too sure 2acu NO 1 1 NPS NPS 8117659 8117659 SwissProt and PISA say monomer -- Annotation transfered from 1ads 2adp PROBYES 2 4 C2 D2 16443160 1394426 BU changed since last release and is now incorrect - Paper says tetramer - automaticaly inferred from 1n0j 2adq PROBYES 2 4 C2 D2 16443160 1394426 BU changed since last release and is now incorrect - Paper says tetramer - automaticaly inferred from 1n0j 2adu PROBNOT 1 1 NPS NPS 16134930 9812898 Paper says nothing, PISA says monomer - automatic transfer from 1b6a 2ady NA 4 4 C2 C2 16793544 8023157 BU changed since last release and is now corrected - I am not sure about that one. 9628871 shows a cartoon of how it bind. Normally, there are 2 palindromic sequences, but in the crystal structure there are only 3 proteins, and the binding mode seems not compatible with that shown in 9628871 - automaticaly inferred from 1tsr 2ae1 YES 1 2 NPS C2 9560196 9560196 Said to be a dimer in the paper and SwissProt 2ae2 NO 2 2 C2 C2 10387002 10387002 paper says 2aeo PROBYES 4 2 NS C2 16416478 1619651 BU changed since last release and is now incorrect - PAper, SP say dimer - automaticaly inferred from 1cob 2afg PROBYES 4 1 NS NPS 8652550 8652550 SP says monomer 2afn NO 3 3 C3 C3 7547950 7547950 -- Annotation transfered from 1as7 2age PROBNOT 1 1 NPS NPS 16636277 0 - automatic transfer from 1az8 2agg PROBNOT 1 1 NPS NPS 16636277 0 - automatic transfer from 1az8 2agi PROBNOT 1 1 NPS NPS 16636277 0 - automatic transfer from 1az8 2ah4 PROBNOT 1 1 NPS NPS 16636277 0 - automatic transfer from 1az8 2ahb NO 2 2 C2 C2 16040614 0 - automatic transfer from 1m1m 2ahi NA 4 4 C2 C2 16793544 8023157 BU changed since last release and is now corrected - I am not sure about that one. 9628871 shows a cartoon of how it bind. Normally, there are 2 palindromic sequences, but in the crystal structure there are only 3 proteins, and the binding mode seems not compatible with that shown in 9628871 - automaticaly inferred from 1tsr 2ai1 PROBNOT 3 3 C3 C3 16239721 15342253 BU changed since last release and is now corrected - Gel-filtration of the enzyme at a concentration of 9.2 mg/ml, corresponding to the concentration used for crystallization, in the presence of 0.2 M CaCl2 leads to a molecular mass of 102 kDa for the enzyme. This is compatible with a trimeric form of the enzyme -- very interesting though since the paper says hexamers exists in orther organisms - automaticaly inferred from 1lvu 2ai2 PROBNOT 3 3 C3 C3 16239721 15342253 BU changed since last release and is now corrected - Gel-filtration of the enzyme at a concentration of 9.2 mg/ml, corresponding to the concentration used for crystallization, in the presence of 0.2 M CaCl2 leads to a molecular mass of 102 kDa for the enzyme. This is compatible with a trimeric form of the enzyme -- very interesting though since the paper says hexamers exists in orther organisms - automaticaly inferred from 1lvu 2ai3 PROBNOT 3 3 C3 C3 16239721 15342253 BU changed since last release and is now corrected - Gel-filtration of the enzyme at a concentration of 9.2 mg/ml, corresponding to the concentration used for crystallization, in the presence of 0.2 M CaCl2 leads to a molecular mass of 102 kDa for the enzyme. This is compatible with a trimeric form of the enzyme -- very interesting though since the paper says hexamers exists in orther organisms - automaticaly inferred from 1lvu 2ai8_1 NO 1 1 NPS NPS 12538898 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 2ai8_2 NO 1 1 NPS NPS 12538898 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 2ai8_3 NO 1 1 NPS NPS 12538898 9374869 9565550 says monomer: PDF from E. coli, a monomeric protein of 168 residues - automatic transfer from 1dff 2ai9_1 PROBNOT 1 1 NPS NPS 12538898 15382235 Paper implies monomer - related protein are monomeric and PISA says monomer - automatic transfer from 1q1y 2ai9_2 PROBNOT 1 1 NPS NPS 12538898 15382235 Paper implies monomer - related protein are monomeric and PISA says monomer - automatic transfer from 1q1y 2aid NO 2 2 C2 C2 8340363 8340363 -- Annotation transfered from 1ajx 2aig PROBYES 2 1 C2 NPS 9521103 9521103 In monomeric metzincins, such as crayfish astacin and adamalysin II -- Annotation transfered from 3aig 2aim NO 1 1 NPS NPS 9260273 9260273 The enzyme is a monomeric glycoprotein -- Annotation transfered from 1me4 2aio PROBNOT 4 4 D2 D2 16218639 9811546 BU changed since last release and is now corrected - Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automaticaly inferred from 1sml 2aix PROBNOT 2 2 C2 C2 0 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 2aj8_1 PROBYES 2 4 C2 D2 16330047 12690074 BU changed since last release and is now incorrect - The tetramer encloses a large cavity and may explain why the high molecular weight form of DP IV behaves as a hexamer on gel filtration chromatography -- very interesting case: exists in two forms, one membranne bound and one soluble. May mediate cell-cell interactions (two mem. bound) or, the soluble could interfere and disrupt the cell-cell interaction - there is a glycosilation important for tetramerization regulation - active site not at the interface. Very complete example for a talk or for teaching or for a paper - automaticaly inferred from 1orv 2aj8_2 PROBYES 2 4 C2 D2 16330047 12690074 BU changed since last release and is now incorrect - The tetramer encloses a large cavity and may explain why the high molecular weight form of DP IV behaves as a hexamer on gel filtration chromatography -- very interesting case: exists in two forms, one membranne bound and one soluble. May mediate cell-cell interactions (two mem. bound) or, the soluble could interfere and disrupt the cell-cell interaction - there is a glycosilation important for tetramerization regulation - active site not at the interface. Very complete example for a talk or for teaching or for a paper - automaticaly inferred from 1orv 2aj9 NO 2 2 C2 C2 16040614 0 - automatic transfer from 1m1m 2ajb_1 PROBYES 2 4 C2 D2 16330047 12690074 BU changed since last release and is now incorrect - The tetramer encloses a large cavity and may explain why the high molecular weight form of DP IV behaves as a hexamer on gel filtration chromatography -- very interesting case: exists in two forms, one membranne bound and one soluble. May mediate cell-cell interactions (two mem. bound) or, the soluble could interfere and disrupt the cell-cell interaction - there is a glycosilation important for tetramerization regulation - active site not at the interface. Very complete example for a talk or for teaching or for a paper - automaticaly inferred from 1orv 2ajb_2 PROBYES 2 4 C2 D2 16330047 12690074 BU changed since last release and is now incorrect - The tetramer encloses a large cavity and may explain why the high molecular weight form of DP IV behaves as a hexamer on gel filtration chromatography -- very interesting case: exists in two forms, one membranne bound and one soluble. May mediate cell-cell interactions (two mem. bound) or, the soluble could interfere and disrupt the cell-cell interaction - there is a glycosilation important for tetramerization regulation - active site not at the interface. Very complete example for a talk or for teaching or for a paper - automaticaly inferred from 1orv 2ajc_1 PROBYES 2 4 C2 D2 16330047 12690074 BU changed since last release and is now incorrect - The tetramer encloses a large cavity and may explain why the high molecular weight form of DP IV behaves as a hexamer on gel filtration chromatography -- very interesting case: exists in two forms, one membranne bound and one soluble. May mediate cell-cell interactions (two mem. bound) or, the soluble could interfere and disrupt the cell-cell interaction - there is a glycosilation important for tetramerization regulation - active site not at the interface. Very complete example for a talk or for teaching or for a paper - automaticaly inferred from 1orv 2ajc_2 PROBYES 2 4 C2 D2 16330047 12690074 BU changed since last release and is now incorrect - The tetramer encloses a large cavity and may explain why the high molecular weight form of DP IV behaves as a hexamer on gel filtration chromatography -- very interesting case: exists in two forms, one membranne bound and one soluble. May mediate cell-cell interactions (two mem. bound) or, the soluble could interfere and disrupt the cell-cell interaction - there is a glycosilation important for tetramerization regulation - active site not at the interface. Very complete example for a talk or for teaching or for a paper - automaticaly inferred from 1orv 2ajd_1 PROBYES 2 4 C2 D2 16330047 12690074 BU changed since last release and is now incorrect - The tetramer encloses a large cavity and may explain why the high molecular weight form of DP IV behaves as a hexamer on gel filtration chromatography -- very interesting case: exists in two forms, one membranne bound and one soluble. May mediate cell-cell interactions (two mem. bound) or, the soluble could interfere and disrupt the cell-cell interaction - there is a glycosilation important for tetramerization regulation - active site not at the interface. Very complete example for a talk or for teaching or for a paper - automaticaly inferred from 1orv 2ajd_2 PROBYES 2 4 C2 D2 16330047 12690074 BU changed since last release and is now incorrect - The tetramer encloses a large cavity and may explain why the high molecular weight form of DP IV behaves as a hexamer on gel filtration chromatography -- very interesting case: exists in two forms, one membranne bound and one soluble. May mediate cell-cell interactions (two mem. bound) or, the soluble could interfere and disrupt the cell-cell interaction - there is a glycosilation important for tetramerization regulation - active site not at the interface. Very complete example for a talk or for teaching or for a paper - automaticaly inferred from 1orv 2ajl NO 2 2 C2 C2 16236500 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2ak2 PROBNOT 1 1 NPS NPS 8868479 8868479 SP says monomer -- Annotation transfered from 1ak2 2ak7 NO 2 2 C2 C2 16411239 12972249 Reversible domain swapping - Whereas HPr is monomeric in solution, Crh forms a mixture of monomers and dimers in a slowly exchanging equilibrium that takes place within a matter of hours. - automatic transfer from 1mu4 2akm NO 2 2 C2 C2 16411755 15289101 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific - gene dup - interesting - automatic transfer from 1te6 2aky PROBNOT 1 1 NPS NPS 7670369 7670369 SP and PISA say monomer 2akz NO 2 2 C2 C2 16411755 15289101 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific - gene dup - interesting - automatic transfer from 1te6 2al1 NO 2 2 C2 C2 16309698 8605183 Interface conserved with 1te6 (62% id) -- Annotation transfered from 1one 2al2 NO 2 2 C2 C2 16309698 8605183 Interface conserved with 1te6 (62% id) -- Annotation transfered from 1one 2al4_1 PROBNOT 2 2 C2 C2 16192394 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 2al4_2 PROBNOT 2 2 C2 C2 16192394 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 2al4_3 PROBNOT 2 2 C2 C2 16192394 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 2al5 PROBNOT 2 2 C2 C2 16192394 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 2alf PROBNOT 1 1 NPS NPS 0 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2alp NO 1 1 NPS NPS 3900416 3900416 9846867 says monomer -- Annotation transfered from 1p05 2alr NO 1 1 NPS NPS 15299353 0 Swissprot and PISA say monomer -- Annotation transfered from 1cwn 2am9 PROBNOT 1 1 NPS NPS 16641486 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 2ama PROBNOT 1 1 NPS NPS 16641486 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 2amb PROBNOT 1 1 NPS NPS 16641486 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 2amg PROBNOT 1 1 NPS NPS 9126844 9126844 SP says monomer -- Annotation transfered from 1gcy 2amv PROBYES 2 2 C2 C2 9384557 9384557 Wrong interface of the dimer 2an9 PROBYES 6 2 D3 C2 16140325 0 BU changed since last release and is now incorrect - SP says: Homotetramer (under low ionic conditions) or homodimer (under high ionic conditions). - automaticaly inferred from 1s96 2anb PROBYES 6 2 D3 C2 16140325 0 BU changed since last release and is now incorrect - SP says: Homotetramer (under low ionic conditions) or homodimer (under high ionic conditions). - automaticaly inferred from 1s96 2anc PROBYES 6 2 D3 C2 16140325 0 BU changed since last release and is now incorrect - SP says: Homotetramer (under low ionic conditions) or homodimer (under high ionic conditions). - automaticaly inferred from 1s96 2ang NO 1 1 NPS NPS 9918722 9918722 Human angiogenin is monomeric -- Annotation transfered from 1h52 2ano PROBNOT 1 1 NPS NPS 17125251 7873554 ECOcyc says monomer - PISA says dimer - automatic transfer from 1drh 2anp NO 1 1 NPS NPS 16142900 10413478 Aminopeptidase from Aeromonas proteolytica (AAP) is a small, monomeric enzyme (32KDa) - automatic transfer from 1cp6 2anq PROBNOT 1 1 NPS NPS 17125251 7873554 ECOcyc says monomer - PISA says dimer - automatic transfer from 1drh 2ans PROBYES 2 1 C2 NPS 10423455 0 ALBP is monomeric at low and high salt concentrations. -- Annotation transfered from 1ab0 2ant_1 PROBYES 1 2 NPS C2 9067613 15342247 BU changed since last release and is now incorrect - 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization - automaticaly inferred from 1jvq 2ant_2 PROBYES 1 2 NPS C2 9067613 15342247 BU changed since last release and is now incorrect - 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization - automaticaly inferred from 1jvq 2anz PROBNOT 1 1 NPS NPS 16490206 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 2ao6 PROBNOT 1 1 NPS NPS 15525515 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 2aos NO 1 1 NPS NPS 0 12529329 Elutes as a monomer - Papers says: The second peak in this final chromatographic step corresponded to a molecular mass of 40 kDa. - automatic transfer from 1ljy 2aps NO 2 2 C2 C2 10656823 10656823 Paper says dimer 2aq8 PROBNOT 4 4 D2 D2 16647717 7886450 BU changed since last release and is now corrected - - automaticaly inferred from 1eny 2aq9 NO 3 3 C3 C3 16835299 7481807 Interface geometry conserved with 1j2z (43%) - automatic transfer from 1lxa 2aqd PROBNOT 1 1 NPS NPS 16490206 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 2aqk PROBNOT 4 4 D2 D2 16647717 7886450 BU changed since last release and is now corrected - - automaticaly inferred from 1eny 2aqu NO 2 2 C2 C2 16634628 9083478 - automatic transfer from 1ajx 2ar6 NO 2 2 C2 C2 16704415 12595543 Implied in paper that it is a dimer, PISA also says that - automatic transfer from 1n3q 2arb NO 2 2 C2 C2 16704415 12595543 Implied in paper that it is a dimer, PISA also says that - automatic transfer from 1n3q 2are NO 2 2 C2 C2 16704415 12595543 Implied in paper that it is a dimer, PISA also says that - automatic transfer from 1n3q 2arm PROBNOT 1 1 NPS NPS 16596639 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2arx NO 2 2 C2 C2 16704415 12595543 Implied in paper that it is a dimer, PISA also says that - automatic transfer from 1n3q 2as1 PROBNOT 1 1 NPS NPS 16490206 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 2as2 PROBNOT 1 1 NPS NPS 16490206 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 2as3 PROBNOT 1 1 NPS NPS 16490206 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 2as4 PROBNOT 1 1 NPS NPS 16490206 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 2as6 PROBNOT 1 1 NPS NPS 16490206 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 2asm PROBNOT 1 1 NPS NPS 16192358 11932258 BU changed since last release and is now corrected - Actin does not form closed dimer - automaticaly inferred from 1lcu 2aso PROBNOT 1 1 NPS NPS 16192358 11932258 BU changed since last release and is now corrected - Actin does not form closed dimer - automaticaly inferred from 1lcu 2asp PROBNOT 1 1 NPS NPS 16192358 11932258 BU changed since last release and is now corrected - Actin does not form closed dimer - automaticaly inferred from 1lcu 2asv NO 2 2 C2 C2 0 10220320 - automatic transfer from 2ecp 2at1 NO 12 12 D3 D3 2405902 2405902 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 2at2 YES 3 3 C3 NAC3 1906175 1906175 BU changed since last release and is now incorrect - -- low resolution (trace only) 2ata NA 4 4 C2 C2 16793544 8023157 BU changed since last release and is now corrected - I am not sure about that one. 9628871 shows a cartoon of how it bind. Normally, there are 2 palindromic sequences, but in the crystal structure there are only 3 proteins, and the binding mode seems not compatible with that shown in 9628871 - automaticaly inferred from 1tsr 2ath PROBYES 2 2 NS C2 16366601 15258145 BU changed since last release and is now incorrect - PISA says homodimer and identicals are homodimers - automaticaly inferred from 1wm0 2ati PROBNOT 2 2 C2 C2 16190745 12204691 BU changed since last release and is now corrected - - automaticaly inferred from 1l7x 2atj_1 PROBNOT 1 1 NPS NPS 9609699 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1gx2 2atj_2 PROBNOT 1 1 NPS NPS 9609699 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1gx2 2ato NO 1 1 NPS NPS 0 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 2ats PROBYES 2 4 C2 D2 0 15066435 BU changed since last release and is now incorrect - Interface geometry conserved with 1fdy (25%) -- interesting QS evolution: interface geometry of these two proteins from e coli is conserved while the geometry with other proteins (closer in seq % id but from other organisms) is not. - automaticaly inferred from 1s5w 2au8 NO 6 6 D3 D3 0 9668207 SP and EcoCyc say hexamer - automatic transfer from 1mjz 2au9 NO 6 6 D3 D3 0 9668207 SP and EcoCyc say hexamer - automatic transfer from 1mjz 2aub NO 1 1 NPS NPS 15930644 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2auu NO 6 6 D3 D3 0 9668207 SP and EcoCyc say hexamer - automatic transfer from 1mjz 2aux NO 1 1 NPS NPS 16290936 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 2auy NO 2 2 C2 C2 16704415 12595543 Implied in paper that it is a dimer, PISA also says that - automatic transfer from 1n3q 2auz NO 1 1 NPS NPS 16290936 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 2av0 NO 2 2 C2 C2 16262242 9826511 Paper and SP say dimer - automatic transfer from 7hbi 2av3 NO 2 2 C2 C2 16262242 9826511 Paper and SP say dimer - automatic transfer from 7hbi 2av6 NO 2 2 C2 C2 0 10220320 - automatic transfer from 2ecp 2avi NO 4 4 D2 D2 8506353 8506353 Avidin is a clear tetramer -- Annotation transfered from 2cam 2aw1 PROBNOT 1 1 NPS NPS 16290146 8987974 9000633 says monomeric - automatic transfer from 1uga 2aw3 NO 2 2 C2 C2 0 10220320 - automatic transfer from 2ecp 2awh PROBNOT 2 2 C2 C2 16405912 10198642 BU changed since last release and is now corrected - Either dimer or monomer but not not symmetrical dimer - automaticaly inferred from 3gwx 2ax2 PROBNOT 1 1 NPS NPS 16511248 8987974 9000633 says monomeric - automatic transfer from 1uga 2ax6 PROBNOT 1 1 NPS NPS 16129672 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 2ax7 PROBNOT 1 1 NPS NPS 16129672 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 2ax9 PROBNOT 1 1 NPS NPS 16129672 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 2axa PROBNOT 1 1 NPS NPS 16129672 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 2axi PROBNOT 1 1 NPS NPS 16511824 8875929 cf. 1rv1 - automatic transfer from 1ycr 2axm PROBYES 2 1 C2 NPS 9655399 9655399 BU changed since last release and is now incorrect - SP says monomer 2ay1 NO 2 2 C2 C2 9930977 9930977 PAper says dimer -- Annotation transfered from 2ay6 2ay2 NO 2 2 C2 C2 9930977 9930977 PAper says dimer -- Annotation transfered from 2ay6 2ay3 NO 2 2 C2 C2 9930977 9930977 PAper says dimer -- Annotation transfered from 2ay6 2ay4 NO 2 2 C2 C2 9930977 9930977 PAper says dimer -- Annotation transfered from 2ay6 2ay5 NO 2 2 C2 C2 9930977 9930977 PAper says dimer -- Annotation transfered from 2ay6 2ay6 NO 2 2 C2 C2 9930977 9930977 PAper says dimer 2ay7 NO 2 2 C2 C2 9930977 9930977 PAper says dimer -- Annotation transfered from 2ay6 2ay8 NO 2 2 C2 C2 9930977 9930977 PAper says dimer -- Annotation transfered from 2ay6 2ay9 NO 2 2 C2 C2 9930977 9930977 PAper says dimer -- Annotation transfered from 2ay6 2ayl NO 2 2 C2 C2 16421446 8121489 - automatic transfer from 1cqe 2ayp PROBNOT 1 1 NPS NPS 16242328 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2ayr PROBYES 1 2 NPS C2 16250633 9338790 BU changed since last release and is now incorrect - paper says dimer - automaticaly inferred from 1err 2ayw PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1az8 2az5 PROBYES 4 3 C2 C3 16284179 0 BU changed since last release and is now incorrect - No paper - SP says trimer - automaticaly inferred from 2tun 2aza_1 NA 1 1 NPS NPS 3210236 0 BU changed since last release and is now corrected - No clear info found - automaticaly inferred from 1azc 2aza_2 NA 1 1 NPS NPS 3210236 0 BU changed since last release and is now corrected - No clear info found - automaticaly inferred from 1azc 2azd NO 2 2 C2 C2 0 10220320 - automatic transfer from 2ecp 2azr PROBNOT 1 1 NPS NPS 16303309 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2azu_1 PROBYES 2 1 C2 NPS 1901363 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 2azu_2 PROBYES 2 1 C2 NPS 1901363 0 BU changed since last release and is now incorrect - This is hard to believe but it seems that azurin is a monomeric protein! - automaticaly inferred from 1azu 2azy PROBYES 1 2 NPS C2 17434532 11170377 BU changed since last release and is now incorrect - Papers of identical structures speak about the dimer as something relevant but it is interesting to note that two modes of dimerization exist among these proteins. I have not seen this discussed - automaticaly inferred from 1fx9 2azz PROBYES 1 2 NPS C2 17434532 11170377 BU changed since last release and is now incorrect - Papers of identical structures speak about the dimer as something relevant but it is interesting to note that two modes of dimerization exist among these proteins. I have not seen this discussed - automaticaly inferred from 1fx9 2b00 PROBYES 1 2 NPS C2 17434532 11170377 BU changed since last release and is now incorrect - Papers of identical structures speak about the dimer as something relevant but it is interesting to note that two modes of dimerization exist among these proteins. I have not seen this discussed - automaticaly inferred from 1fx9 2b01 PROBYES 1 2 NPS C2 17434532 11170377 BU changed since last release and is now incorrect - Papers of identical structures speak about the dimer as something relevant but it is interesting to note that two modes of dimerization exist among these proteins. I have not seen this discussed - automaticaly inferred from 1fx9 2b03 PROBYES 1 2 NPS C2 17434532 11170377 BU changed since last release and is now incorrect - Papers of identical structures speak about the dimer as something relevant but it is interesting to note that two modes of dimerization exist among these proteins. I have not seen this discussed - automaticaly inferred from 1fx9 2b04 PROBYES 1 2 NPS C2 17434532 11170377 BU changed since last release and is now incorrect - Papers of identical structures speak about the dimer as something relevant but it is interesting to note that two modes of dimerization exist among these proteins. I have not seen this discussed - automaticaly inferred from 1fx9 2b07 PROBNOT 1 1 NPS NPS 16303309 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2b08 NO 3 3 C3 C3 17227014 9353305 - automatic transfer from 1as7 2b14 NO 4 4 D2 D2 16627944 11106758 - automatic transfer from 1g1o 2b15 NO 4 4 D2 D2 16627944 11106758 - automatic transfer from 1g1o 2b17 PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2b1j_1 PROBNOT 1 1 NPS NPS 17050923 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 2b1j_2 PROBNOT 1 1 NPS NPS 17050923 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 2b1p PROBNOT 1 1 NPS NPS 16140012 12954329 - automatic transfer from 1pmv 2b2k PROBYES 2 1 C2 NPS 16617181 12540835 Seems to be a monomer - PISA would be wrong - automatic transfer from 1nfs 2b31 NO 1 1 NPS NPS 0 12529329 Elutes as a monomer - Papers says: The second peak in this final chromatographic step corresponded to a molecular mass of 40 kDa. - automatic transfer from 1ljy 2b35_1 PROBNOT 4 4 D2 D2 -1 7886450 BU changed since last release and is now corrected - - automaticaly inferred from 1eny 2b35_2 PROBNOT 4 4 D2 D2 -1 7886450 BU changed since last release and is now corrected - - automaticaly inferred from 1eny 2b36_1 PROBNOT 4 4 D2 D2 -1 7886450 BU changed since last release and is now corrected - - automaticaly inferred from 1eny 2b36_2 PROBNOT 4 4 D2 D2 -1 7886450 BU changed since last release and is now corrected - - automaticaly inferred from 1eny 2b37_1 PROBNOT 4 4 D2 D2 -1 7886450 BU changed since last release and is now corrected - - automaticaly inferred from 1eny 2b37_2 PROBNOT 4 4 D2 D2 -1 7886450 BU changed since last release and is now corrected - - automaticaly inferred from 1eny 2b3s_1 NA 1 1 NPS NPS 0 10700276 BU changed since last release and is now corrected - It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant - automaticaly inferred from 1ac1 2b3s_2 NA 1 1 NPS NPS 0 10700276 BU changed since last release and is now corrected - It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant - automaticaly inferred from 1ac1 2b3u NO 2 2 C2 C2 16455797 16455797 Paper says dimer -- Annotation transfered from 2b3v 2b3v NO 2 2 C2 C2 16455797 16455797 Paper says dimer 2b4b NO 2 2 C2 C2 16455797 16455797 Paper says dimer -- Annotation transfered from 2b3v 2b4d NO 2 2 C2 C2 16455797 16455797 Paper says dimer -- Annotation transfered from 2b3v 2b50_1 YES 1 2 NPS C2 16405912 10198642 BU changed since last release and is now incorrect - Either dimer or monomer but not not symmetrical dimer - automaticaly inferred from 3gwx 2b50_2 YES 1 2 NPS C2 16405912 10198642 BU changed since last release and is now incorrect - Either dimer or monomer but not not symmetrical dimer - automaticaly inferred from 3gwx 2b52 NO 1 1 NPS NPS 14698155 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2b53 NO 1 1 NPS NPS 11354366 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2b54 NO 1 1 NPS NPS 15537345 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2b55 NO 1 1 NPS NPS 12431051 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2b58 NO 2 2 C2 C2 16455797 16455797 Paper says dimer -- Annotation transfered from 2b3v 2b5g NO 2 2 C2 C2 16455797 16455797 Paper says dimer -- Annotation transfered from 2b3v 2b5z NO 1 1 NPS NPS 0 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2b63 NO 12 12 NPS NPS 16341226 17290000 RNA Pol II complex -- Annotation transfered from 2ja5 2b6m_1 NA 1 1 NPS NPS 0 10700276 BU changed since last release and is now corrected - It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant - automaticaly inferred from 1ac1 2b6m_2 NA 1 1 NPS NPS 0 10700276 BU changed since last release and is now corrected - It seems that it is accepted that the protein is a monomer, although it was observed that Human Thioredoxin can form dimers (which function remains unknown). Plus the dimeric form of v. cholerae has 40% seq id and uses the same interface. --> So I believe this dimer is phisiologicaly relevant - automaticaly inferred from 1ac1 2b6t NO 1 1 NPS NPS 17292912 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2b6w NO 1 1 NPS NPS 16269539 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2b6x NO 1 1 NPS NPS 16269539 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2b6y NO 1 1 NPS NPS 16269539 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2b6z NO 1 1 NPS NPS 16269539 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2b70 NO 1 1 NPS NPS 16269539 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2b72 NO 1 1 NPS NPS 16269539 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2b73 NO 1 1 NPS NPS 16269539 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2b74 NO 1 1 NPS NPS 16269539 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2b75 NO 1 1 NPS NPS 16269539 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2b77 NO 4 4 D2 D2 14711308 11106758 - automatic transfer from 1g1o 2b7r PROBNOT 1 1 NPS NPS 16699170 10581550 SP says monomer - automatic transfer from 1qjd 2b7s PROBNOT 1 1 NPS NPS 16699170 10581550 SP says monomer - automatic transfer from 1qjd 2b83 NO 4 4 D2 D2 17063493 12381840 - automatic transfer from 1jqb 2b8k NO 12 12 NPS NPS 16765890 17290000 RNA Pol II complex -- Annotation transfered from 2ja5 2b8u PROBNOT 1 1 NPS NPS 16640778 11526337 - automatic transfer from 1hzi 2b9a NO 4 4 D2 D2 14711308 11106758 - automatic transfer from 1g1o 2bag PROBYES 2 4 C2 NA 16913695 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 2baj PROBNOT 1 1 NPS NPS 16342939 11896401 - automatic transfer from 1kv1 2bak PROBNOT 1 1 NPS NPS 16342939 11896401 - automatic transfer from 1kv1 2bal PROBNOT 1 1 NPS NPS 16342939 11896401 - automatic transfer from 1kv1 2bat PROBNOT 4 4 C4 C4 1438172 0 BU changed since last release and is now corrected - The paper does not describe the quaternary state. Comparision of the structure with 1ivd shows a very similar structure, and no ligand bound at the interface. So there is apparently no reason why the QS would differ. - automaticaly inferred from 1inw 2baw_1 YES 1 2 NPS C2 16387648 10198642 BU changed since last release and is now incorrect - Either dimer or monomer but not not symmetrical dimer - automaticaly inferred from 3gwx 2baw_2 YES 1 2 NPS C2 16387648 10198642 BU changed since last release and is now incorrect - Either dimer or monomer but not not symmetrical dimer - automaticaly inferred from 3gwx 2bax PROBNOT 1 1 NPS NPS 16508077 14529623 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution - automatic transfer from 1o2e 2bb2 PROBYES 4 2 D2 C2 2234050 12084052 B2-crystallin is a dimer in solution -- very interesting review: about evolution of oligomers! 2bb4 PROBNOT 1 1 NPS NPS 0 9443341 - automatic transfer from 1c1m 2bb9 NO 2 2 C2 C2 16298527 9083478 - automatic transfer from 1ajx 2bbb NO 2 2 C2 C2 16298527 9083478 - automatic transfer from 1ajx 2bbq NO 2 2 C2 C2 1390771 1390771 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 2bc2_1 PROBNOT 1 1 NPS NPS 0 9730812 BU changed since last release and is now corrected - there is no evidence for dimerization of the enzyme in solution. - automaticaly inferred from 1bc2 2bc2_2 PROBNOT 1 1 NPS NPS 0 9730812 BU changed since last release and is now corrected - there is no evidence for dimerization of the enzyme in solution. - automaticaly inferred from 1bc2 2bc3 NO 4 4 D2 D2 16384581 9148939 BU changed since last release and is now corrected - - automatic transfer from 1vwl 2bce NO 1 1 NPS NPS 9548741 9548741 Paper says monomer 2bd2 PROBNOT 1 1 NPS NPS 0 9443341 - automatic transfer from 1c1m 2bd3 PROBNOT 1 1 NPS NPS 0 9443341 - automatic transfer from 1c1m 2bd4 PROBNOT 1 1 NPS NPS 0 9443341 - automatic transfer from 1c1m 2bd5 PROBNOT 1 1 NPS NPS 0 9443341 - automatic transfer from 1c1m 2bd7 PROBNOT 1 1 NPS NPS 0 9443341 - automatic transfer from 1c1m 2bd8 PROBNOT 1 1 NPS NPS 0 9443341 - automatic transfer from 1c1m 2bd9 PROBNOT 1 1 NPS NPS 0 9443341 - automatic transfer from 1c1m 2bda PROBNOT 1 1 NPS NPS 0 9443341 - automatic transfer from 1c1m 2bdb PROBNOT 1 1 NPS NPS 0 9443341 - automatic transfer from 1c1m 2bdc PROBNOT 1 1 NPS NPS 0 9443341 - automatic transfer from 1c1m 2bdl NO 1 1 NPS NPS 16376075 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 2bdm NO 1 1 NPS NPS 16373351 14563924 Paper says monomer dimer equilibrium - automatic transfer from 1po5 2bdy PROBNOT 1 1 NPS NPS 16290930 11053836 - automatic transfer from 1doj 2bef NO 6 6 D3 D3 9108019 9108019 SP, PISA and paper say hexamer -- Annotation transfered from 1b4s 2beh PROBNOT 2 2 C2 C2 0 15342247 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization - automatic transfer from 1jvq 2bf7 NO 4 4 D2 D2 16055151 0 - automatic transfer from 1e92 2bfa NO 4 4 D2 D2 16055151 0 - automatic transfer from 1e92 2bfh PROBNOT 1 1 NPS NPS 1769963 1769963 SP says monomer -- Annotation transfered from 1bas 2bfm NO 4 4 D2 D2 16055151 0 - automatic transfer from 1e92 2bfn NO 1 1 NPS NPS 17259360 11939779 SP says monomer - automatic transfer from 1g42 2bfo NO 4 4 D2 D2 16055151 0 - automatic transfer from 1e92 2bfp NO 4 4 D2 D2 16055151 0 - automatic transfer from 1e92 2bgd PROBNOT 1 1 NPS NPS 15863305 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2bge PROBNOT 1 1 NPS NPS 15863305 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2bgr NO 2 2 C2 C2 15695814 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2bgt PROBNOT 1 1 NPS NPS 8062817 8062817 SP says monomer -- Annotation transfered from 1bgt 2bgu PROBNOT 1 1 NPS NPS 8062817 8062817 SP says monomer -- Annotation transfered from 1bgt 2bh3 NO 4 4 D2 D2 16229471 15388923 Paper says tetramer - automatic transfer from 1n51 2bha NO 4 4 D2 D2 16229471 15388923 Paper says tetramer - automatic transfer from 1n51 2bhb NO 4 4 D2 D2 16229471 15388923 Paper says tetramer - automatic transfer from 1n51 2bhc NO 4 4 D2 D2 16229471 15388923 Paper says tetramer - automatic transfer from 1n51 2bhd NO 4 4 D2 D2 16229471 15388923 Paper says tetramer - automatic transfer from 1n51 2bhe NO 1 1 NPS NPS 15742375 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2bhf PROBNOT 1 1 NPS NPS 16234932 14764581 Paper says nothing, PISA says monomer - automatic transfer from 1hl0 2bhh NO 1 1 NPS NPS 15742375 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2bhj PROBYES 2 1 C2 NPS 15781384 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 2bi4 NO 2 2 C2 C2 15995211 0 Interfave geometry conserved with 1vhd (31%) - automatic transfer from 1rrm 2bj9 NA 4 4 C2 C2 15826657 15826657 this is a test 2bjs NA 1 1 NPS NPS 0 7791906 BU changed since last release and is now corrected - Might be interesting to discuss in the paper - So the difference in the two crystallised forms is a combination of the crystallisation conditions and the conformational change upon substrate binding. Biological significance? Intuitively, I would say - probably none I hope this helps, Cheers, Pete - automaticaly inferred from 1ips 2bjy NO 12 12 Tetr Tetr 15823016 10625425 Interface geometry conserved with 1o9r (25%) - automatic transfer from 1qgh 2bk3 NO 2 2 C2 C2 15710600 11753429 BU changed since last release and is now corrected - - automatic transfer from 1ojd_4 2bk4 NO 2 2 C2 C2 15710600 11753429 BU changed since last release and is now corrected - - automatic transfer from 1ojd_4 2bk5 NO 2 2 C2 C2 15710600 11753429 BU changed since last release and is now corrected - - automatic transfer from 1ojd_4 2bk6 NO 12 12 Tetr Tetr 15823016 10625425 Interface geometry conserved with 1o9r (25%) - automatic transfer from 1qgh 2bkb_1 NO 2 2 C2 C2 16430211 7849024 Paper says dimer - automatic transfer from 1isc 2bkb_2 NO 2 2 C2 C2 16430211 7849024 Paper says dimer - automatic transfer from 1isc 2bkc_1 NO 12 12 Tetr Tetr 15823016 10625425 Interface geometry conserved with 1o9r (25%) - automatic transfer from 1qgh 2bkc_2 NO 12 12 Tetr Tetr 15823016 10625425 Interface geometry conserved with 1o9r (25%) - automatic transfer from 1qgh 2bl4 NO 2 2 C2 C2 15995211 0 Interfave geometry conserved with 1vhd (31%) - automatic transfer from 1rrm 2blg PROBNOT 2 2 C2 C2 9760236 9760236 SP says: Under physiological conditions beta-lactoglobulin exists as an equilibrium mixture of monomeric and dimeric forms 2blh NO 1 1 NPS NPS 15794647 0 Myoglobin is a monomeric protein (8663546) - automatic transfer from 1a6m 2bli NO 1 1 NPS NPS 15794647 0 Myoglobin is a monomeric protein (8663546) - automatic transfer from 1a6m 2blj NO 1 1 NPS NPS 15794647 0 Myoglobin is a monomeric protein (8663546) - automatic transfer from 1a6m 2blm_1 PROBNOT 1 1 NPS NPS 2326252 11827533 BU changed since last release and is now corrected - Paper says nothing and PISA says monomeric - automaticaly inferred from 1i2w 2blm_2 PROBNOT 1 1 NPS NPS 2326252 11827533 BU changed since last release and is now corrected - Paper says nothing and PISA says monomeric - automaticaly inferred from 1i2w 2blo PROBNOT 1 1 NPS NPS 16131756 9443341 - automatic transfer from 1c1m 2blp PROBNOT 1 1 NPS NPS 16131756 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 2blq PROBNOT 1 1 NPS NPS 16131756 9443341 - automatic transfer from 1c1m 2blr PROBNOT 1 1 NPS NPS 16131756 10504569 BU changed since last release and is now corrected - Thaumatin is a stable monomeric protein of 22kDa - automaticaly inferred from 1thw 2bls PROBYES 2 1 C2 NPS 9819201 9819201 AmpC is a class C beta Lactamase and those are monomeric (12951239) -- Annotation transfered from 1c3b 2blu PROBNOT 1 1 NPS NPS 16131756 10504569 BU changed since last release and is now corrected - Thaumatin is a stable monomeric protein of 22kDa - automaticaly inferred from 1thw 2blv PROBNOT 1 1 NPS NPS 16131756 0 - automatic transfer from 1az8 2blw PROBNOT 1 1 NPS NPS 16131756 0 - automatic transfer from 1az8 2blx NO 1 1 NPS NPS 16131756 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2bly NO 1 1 NPS NPS 16131756 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2blz PROBNOT 1 1 NPS NPS 16131756 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 2bm2 NO 4 4 D2 D2 15781396 9521329 The paper shows tha tit is a tetramer. In addition, it is would be active only as a tetramer - automatic transfer from 1a0l 2bmh_1 NA 1 1 NPS NPS 15299332 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 2bmh_2 NA 1 1 NPS NPS 15299332 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 2bmi PROBYES 2 1 C2 NPS 9761816 9761816 Paper says: The metallo-[beta]-lactamases are monomeric except for the Stenotrophomonas enzyme which is tetrameric - no dimer mentioned 2bmw NO 1 1 NPS NPS 0 8890910 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) - automatic transfer from 1que 2bn7 NO 4 4 D2 D2 16229471 15388923 Paper says tetramer - automatic transfer from 1n51 2bo0 NO 3 3 C3 C3 0 0 Active site at the monomer-monomer interface - automatic transfer from 1oe3 2bod NA 1 2 NPS C2 16185060 8399160 Full size protein is dimeric (cf. SP references), I dont know wether this fragment should be as well. - automatic transfer from 1tml 2bp2 PROBNOT 1 1 NPS NPS -1 0 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1o2e 2bpp PROBYES 2 1 C2 NPS 1751497 1751497 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1bpq 2bpu NO 1 1 NPS NPS 0 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2bpv NO 2 2 C2 C2 9757136 9757136 -- Annotation transfered from 1ajx 2bpw NO 2 2 C2 C2 9757136 9757136 -- Annotation transfered from 1ajx 2bpx NO 2 2 C2 C2 9757136 9757136 -- Annotation transfered from 1ajx 2bpy NO 2 2 C2 C2 9757136 9757136 -- Annotation transfered from 1ajx 2bpz NO 2 2 C2 C2 9757136 9757136 -- Annotation transfered from 1ajx 2bqa NO 1 1 NPS NPS 9677301 9677301 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2bqb NO 1 1 NPS NPS 9677301 9677301 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2bqc NO 1 1 NPS NPS 9677301 9677301 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2bqd NO 1 1 NPS NPS 9677301 9677301 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2bqe NO 1 1 NPS NPS 9677301 9677301 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2bqf NO 1 1 NPS NPS 9677301 9677301 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2bqg NO 1 1 NPS NPS 9677301 9677301 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2bqh NO 1 1 NPS NPS 9677301 9677301 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2bqi NO 1 1 NPS NPS 9677301 9677301 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2bqj NO 1 1 NPS NPS 9677301 9677301 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2bqk NO 1 1 NPS NPS 9677301 9677301 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2bql NO 1 1 NPS NPS 9677301 9677301 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2bqm NO 1 1 NPS NPS 9677301 9677301 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2bqn NO 1 1 NPS NPS 9677301 9677301 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2bqo NO 1 1 NPS NPS 9677301 9677301 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2bqp NA 2 2 C2 C2 -1 0 2bqv NO 2 2 C2 C2 16335934 9083478 - automatic transfer from 1ajx 2br1 PROBNOT 1 1 NPS NPS 15974586 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2brb PROBNOT 1 1 NPS NPS 15974586 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2brc PROBYES 1 2 NPS C2 15955698 9230303 BU changed since last release and is now incorrect - - automaticaly inferred from 1a4h 2brd NO 3 3 C3 C3 8676377 8676377 SP says trimer 2bre_1 PROBYES 1 2 NPS C2 15955698 9230303 BU changed since last release and is now incorrect - - automaticaly inferred from 1a4h 2bre_2 PROBYES 1 2 NPS C2 15955698 9230303 BU changed since last release and is now incorrect - - automaticaly inferred from 1a4h 2brg PROBNOT 1 1 NPS NPS 15974586 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2brh PROBNOT 1 1 NPS NPS 15974586 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2brk PROBNOT 1 1 NPS NPS 0 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2brm PROBNOT 1 1 NPS NPS 15974586 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2brn PROBNOT 1 1 NPS NPS 15974586 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2bro PROBNOT 1 1 NPS NPS 15974586 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2brs_1 NA 1 2 NPS C2 16245931 11319227 BU changed since last release and is now incorrect - Paper shows the dimer but no evidence - PISA give another form and to me, both have very weak interfaces. - automatic transfer from 1h8u_1 2brs_2 NA 1 2 NPS C2 16245931 11319227 BU changed since last release and is now incorrect - Paper shows the dimer but no evidence - PISA give another form and to me, both have very weak interfaces. - automatic transfer from 1h8u_1 2brt PROBNOT 1 1 NPS NPS 16106293 0 No info about olig. state in the paper, PISA says monomer. Given all similar enzymes function as monomers, I ll say it s true. - automatic transfer from 1gp4 2bsa NO 1 1 NPS NPS 16216071 8890910 FNR is active as a monomer (Lax & al. Photosynthesis Research, 1985) - automatic transfer from 1que 2bsl NO 2 2 C2 C2 0 12732650 - automatic transfer from 1jub 2bsm NA 2 1 C2 NPS 15974572 0 BU changed since last release and is now incorrect - 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automaticaly inferred from 1uy6 2bsx PROBNOT 6 6 D3 D3 16131758 0 BU changed since last release and is now corrected - Identical/homologs are true hexamers and PISA says hexamer - automaticaly inferred from 1sq6 2bt0_1 NA 2 1 C2 NPS 15974572 0 BU changed since last release and is now incorrect - 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automaticaly inferred from 1uy6 2bt0_2 NA 2 1 C2 NPS 15974572 0 BU changed since last release and is now incorrect - 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automaticaly inferred from 1uy6 2bt3 NO 2 2 C2 C2 16157884 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 2bt6_1 PROBNOT 1 1 NPS NPS 16411746 9551550 BU changed since last release and is now corrected - Paper says nothing, PISA implies monomer - automaticaly inferred from 1ayf 2bt6_2 PROBNOT 1 1 NPS NPS 16411746 9551550 BU changed since last release and is now corrected - Paper says nothing, PISA implies monomer - automaticaly inferred from 1ayf 2btm NO 2 2 C2 C2 10383424 10383424 Interface geometry conserved with 1m6j (43%) - paper says dimer 2btr NO 1 1 NPS NPS 16260160 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2bts NO 1 1 NPS NPS 16260160 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2bu9 NA 1 1 NPS NPS 16143309 7791906 BU changed since last release and is now corrected - Might be interesting to discuss in the paper - So the difference in the two crystallised forms is a combination of the crystallisation conditions and the conformational change upon substrate binding. Biological significance? Intuitively, I would say - probably none I hope this helps, Cheers, Pete - automaticaly inferred from 1ips 2bua_1 PROBYES 2 4 C2 D2 16376544 12690074 BU changed since last release and is now incorrect - The tetramer encloses a large cavity and may explain why the high molecular weight form of DP IV behaves as a hexamer on gel filtration chromatography -- very interesting case: exists in two forms, one membranne bound and one soluble. May mediate cell-cell interactions (two mem. bound) or, the soluble could interfere and disrupt the cell-cell interaction - there is a glycosilation important for tetramerization regulation - active site not at the interface. Very complete example for a talk or for teaching or for a paper - automaticaly inferred from 1orv 2bua_2 PROBYES 2 4 C2 D2 16376544 12690074 BU changed since last release and is now incorrect - The tetramer encloses a large cavity and may explain why the high molecular weight form of DP IV behaves as a hexamer on gel filtration chromatography -- very interesting case: exists in two forms, one membranne bound and one soluble. May mediate cell-cell interactions (two mem. bound) or, the soluble could interfere and disrupt the cell-cell interaction - there is a glycosilation important for tetramerization regulation - active site not at the interface. Very complete example for a talk or for teaching or for a paper - automaticaly inferred from 1orv 2bub_1 PROBYES 1 2 NPS C2 16376544 15175333 BU changed since last release and is now incorrect - Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automaticaly inferred from 1tkr 2bub_2 PROBYES 1 2 NPS C2 16376544 15175333 BU changed since last release and is now incorrect - Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automaticaly inferred from 1tkr 2buc_1 PROBYES 2 4 C2 D2 16376544 12690074 BU changed since last release and is now incorrect - The tetramer encloses a large cavity and may explain why the high molecular weight form of DP IV behaves as a hexamer on gel filtration chromatography -- very interesting case: exists in two forms, one membranne bound and one soluble. May mediate cell-cell interactions (two mem. bound) or, the soluble could interfere and disrupt the cell-cell interaction - there is a glycosilation important for tetramerization regulation - active site not at the interface. Very complete example for a talk or for teaching or for a paper - automaticaly inferred from 1orv 2buc_2 PROBYES 2 4 C2 D2 16376544 12690074 BU changed since last release and is now incorrect - The tetramer encloses a large cavity and may explain why the high molecular weight form of DP IV behaves as a hexamer on gel filtration chromatography -- very interesting case: exists in two forms, one membranne bound and one soluble. May mediate cell-cell interactions (two mem. bound) or, the soluble could interfere and disrupt the cell-cell interaction - there is a glycosilation important for tetramerization regulation - active site not at the interface. Very complete example for a talk or for teaching or for a paper - automaticaly inferred from 1orv 2bve_1 PROBNOT 1 1 NPS NPS 17137591 9660955 Paper doesnt mention a dimer and PISA says monomer - automatic transfer from 1qfp 2bve_2 PROBNOT 1 1 NPS NPS 17137591 9660955 Paper doesnt mention a dimer and PISA says monomer - automatic transfer from 1qfp 2bvn_1 PROBNOT 1 1 NPS NPS 16257965 9838020 BU changed since last release and is now corrected - EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa. - automaticaly inferred from 1dg1 2bvn_2 PROBNOT 1 1 NPS NPS 16257965 9838020 BU changed since last release and is now corrected - EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa. - automaticaly inferred from 1dg1 2bvv PROBNOT 1 1 NPS NPS 10220321 10220321 Paper says nothing and PISA says monomer -- Annotation transfered from 1xnb 2bvw PROBYES 2 1 NS NPS 10413461 10413461 BU changed since last release and is now incorrect - Paper says nothing, PISA says monomer -- Annotation transfered from 1ocb 2bw1 NO 12 12 Tetr Tetr 16997323 0 Interface geometry conserved with 1o9r (30%) - automatic transfer from 1umn 2bw4 NO 3 3 C3 C3 16093314 7499203 - automatic transfer from 2nrd 2bw5 NO 3 3 C3 C3 16093314 7499203 - automatic transfer from 2nrd 2bw9 PROBYES 6 1 C6 NPS 16085709 0 BU changed since last release and is now incorrect - Myoglobin is a monomeric protein (8663546) - automaticaly inferred from 1a6m 2bwd NO 3 3 C3 C3 16093314 7499203 - automatic transfer from 2nrd 2bwh NO 1 1 NPS NPS 16085709 0 Myoglobin is a monomeric protein (8663546) - automatic transfer from 1a6m 2bwi NO 3 3 C3 C3 16093314 7499203 - automatic transfer from 2nrd 2bws NO 4 4 D2 D2 16411772 15388923 Paper says tetramer - automatic transfer from 1n51 2bwt NO 4 4 D2 D2 16411772 15388923 Paper says tetramer - automatic transfer from 1n51 2bwu NO 4 4 D2 D2 16411772 15388923 Paper says tetramer - automatic transfer from 1n51 2bwv NO 4 4 D2 D2 16411772 15388923 Paper says tetramer - automatic transfer from 1n51 2bww NO 4 4 D2 D2 16411772 15388923 Paper says tetramer - automatic transfer from 1n51 2bwx NO 4 4 D2 D2 16411772 15388923 Paper says tetramer - automatic transfer from 1n51 2bwy NO 4 4 D2 D2 16411772 15388923 Paper says tetramer - automatic transfer from 1n51 2bx7 NO 2 2 C2 C2 0 12732650 - automatic transfer from 1jub 2by5 PROBNOT 1 1 NPS NPS 16421442 0 - automatic transfer from 1az8 2by6 PROBNOT 1 1 NPS NPS 16421442 0 - automatic transfer from 1az8 2by7 PROBNOT 1 1 NPS NPS 16421442 0 - automatic transfer from 1az8 2by8 PROBNOT 1 1 NPS NPS 16421442 0 - automatic transfer from 1az8 2by9 PROBNOT 1 1 NPS NPS 16421442 0 - automatic transfer from 1az8 2bya PROBNOT 1 1 NPS NPS 16421442 0 - automatic transfer from 1az8 2byb NO 2 2 C2 C2 0 11753429 BU changed since last release and is now corrected - - automatic transfer from 1ojd_4 2byh NA 1 1 NPS NPS 16213716 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automatic transfer from 1uy6 2byi NA 1 1 NPS NPS 16213716 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automatic transfer from 1uy6 2byj_1 PROBNOT 2 2 C2 C2 16096275 9514741 BU changed since last release and is now corrected - Although the paper mentions an hexamer found in the crystal no evidence is shown that is exists in solution. - automaticaly inferred from 1oat 2byj_2 PROBNOT 2 2 C2 C2 16096275 9514741 BU changed since last release and is now corrected - Although the paper mentions an hexamer found in the crystal no evidence is shown that is exists in solution. - automaticaly inferred from 1oat 2byl_1 PROBNOT 2 2 C2 C2 16096275 9514741 BU changed since last release and is now corrected - Although the paper mentions an hexamer found in the crystal no evidence is shown that is exists in solution. - automaticaly inferred from 1oat 2byl_2 PROBNOT 2 2 C2 C2 16096275 9514741 BU changed since last release and is now corrected - Although the paper mentions an hexamer found in the crystal no evidence is shown that is exists in solution. - automaticaly inferred from 1oat 2bz5_1 NA 1 1 NPS NPS 16202589 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automatic transfer from 1uy6 2bz5_2 NA 1 1 NPS NPS 16202589 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automatic transfer from 1uy6 2bz9_1 PROBYES 2 1 C2 NPS 17846131 0 BU changed since last release and is now incorrect - 11304120 says P450s are monomeric enzymes - automaticaly inferred from 1u13 2bz9_2 PROBNOT 1 1 NPS NPS 17846131 0 11304120 says P450s are monomeric enzymes - automatic transfer from 1u13 2bza PROBNOT 1 1 NPS NPS 10651279 10651279 -- Annotation transfered from 1az8 2bzs NO 2 2 C2 C2 16302811 10433694 - automatic transfer from 1qr2 2bzz PROBNOT 1 1 NPS NPS 16401072 11154698 - automatic transfer from 1hi2 2c01 PROBNOT 1 1 NPS NPS 16401072 11154698 - automatic transfer from 1hi2 2c02 PROBNOT 1 1 NPS NPS 16401072 11154698 - automatic transfer from 1hi2 2c05 PROBNOT 1 1 NPS NPS 16401072 11154698 - automatic transfer from 1hi2 2c0r NO 2 2 C2 C2 16532449 0 - automatic transfer from 1bt4 2c1a NO 1 1 NPS NPS 16249095 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 2c1b NO 1 1 NPS NPS 16249095 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 2c1h NO 8 8 D4 D4 16304458 15327955 Paper says octamer - automatic transfer from 1w1z 2c1j_1 NO 2 2 C2 C2 16246723 10488331 14-3-3c forms the canonical dimer found in mammalian 14-3-3 proteins - automatic transfer from 1qjb 2c1n_1 PROBYES 1 2 NPS C2 16246723 10488331 BU changed since last release and is now incorrect - 14-3-3c forms the canonical dimer found in mammalian 14-3-3 proteins - automaticaly inferred from 1qjb 2c1n_2 PROBYES 1 2 NPS C2 16246723 10488331 BU changed since last release and is now incorrect - 14-3-3c forms the canonical dimer found in mammalian 14-3-3 proteins - automaticaly inferred from 1qjb 2c2c PROBNOT 1 1 NPS NPS -1 0 -- Annotation transfered from 3c2c 2c2s_1 PROBNOT 1 1 NPS NPS 17569517 15039552 - automatic transfer from 1s3u 2c2s_2 PROBNOT 1 1 NPS NPS 17569517 15039552 - automatic transfer from 1s3u 2c2t_1 PROBNOT 1 1 NPS NPS 17569517 15039552 - automatic transfer from 1s3u 2c2t_2 PROBNOT 1 1 NPS NPS 17569517 15039552 - automatic transfer from 1s3u 2c3c NO 2 2 C2 C2 16388586 12390015 Paper says dimer - automatic transfer from 1mo9 2c3d NO 2 2 C2 C2 16388586 12390015 Paper says dimer - automatic transfer from 1mo9 2c3j PROBNOT 1 1 NPS NPS 16289938 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2c3k PROBNOT 1 1 NPS NPS 16289938 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2c3l PROBNOT 1 1 NPS NPS 16289938 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2c4h PROBYES 1 4 NPS NA 16763558 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 2c4j_1 NO 2 2 C2 C2 0 8182750 - automatic transfer from 1hna 2c4j_2 NO 2 2 C2 C2 0 8182750 - automatic transfer from 1hna 2c4v PROBYES 2 12 C2 Tetr 16480265 12784220 BU changed since last release and is now incorrect - Interface geometry conserved with 1h0s (38%) - automaticaly inferred from 1j2y 2c57 NO 12 12 Tetr Tetr 16480265 12784220 Interface geometry conserved with 1h0s (38%) - automatic transfer from 1j2y 2c58 PROBYES 1 4 NPS NA 16763558 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 2c5f PROBYES 1 4 NPS NA 16763558 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 2c5g PROBYES 1 4 NPS NA 16763558 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 2c5l_1 PROBNOT 2 2 NPS NPS 16483931 16483931 Paper points to this structure as being biological 2c5l_2 PROBNOT 2 2 NPS NPS 16483931 16483931 Paper points to this structure as being biological -- Annotation transfered from 2c5l_1 2c5y NO 1 1 NPS NPS 16492568 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2c64 NO 2 2 C2 C2 16366596 11753429 BU changed since last release and is now corrected - - automatic transfer from 1ojd_4 2c65 NO 2 2 C2 C2 16366596 11753429 BU changed since last release and is now corrected - - automatic transfer from 1ojd_4 2c66 NO 2 2 C2 C2 16366596 11753429 BU changed since last release and is now corrected - - automatic transfer from 1ojd_4 2c67 NO 2 2 C2 C2 16366596 11753429 BU changed since last release and is now corrected - - automatic transfer from 1ojd_4 2c68 NO 1 1 NPS NPS 16325401 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2c69 NO 1 1 NPS NPS 16325401 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2c6i NO 1 1 NPS NPS 16325401 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2c6k NO 1 1 NPS NPS 16325401 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2c6l NO 1 1 NPS NPS 16325401 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2c6m NO 1 1 NPS NPS 16325401 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2c6o NO 1 1 NPS NPS 16325401 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2c70 NO 2 2 C2 C2 16605246 11753429 BU changed since last release and is now corrected - - automatic transfer from 1ojd_4 2c72 NO 2 2 C2 C2 16605246 11753429 BU changed since last release and is now corrected - - automatic transfer from 1ojd_4 2c73 NO 2 2 C2 C2 16605246 11753429 BU changed since last release and is now corrected - - automatic transfer from 1ojd_4 2c75 NO 2 2 C2 C2 16605246 11753429 BU changed since last release and is now corrected - - automatic transfer from 1ojd_4 2c76 NO 2 2 C2 C2 16605246 11753429 BU changed since last release and is now corrected - - automatic transfer from 1ojd_4 2c77 NO 1 1 NPS NPS 16734421 9838020 BU changed since last release and is now corrected - EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa. - automatic transfer from 1ha3_1 2c78 NO 1 1 NPS NPS 16734421 9838020 BU changed since last release and is now corrected - EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa. - automatic transfer from 1ha3_1 2c80 NO 2 2 C2 C2 16777141 0 - automatic transfer from 1oe8 2c89_1 PROBNOT 1 1 NPS NPS 0 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer - automatic transfer from 1gze_2 2c89_2 PROBNOT 1 1 NPS NPS 0 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer - automatic transfer from 1gze_2 2c89_3 PROBNOT 1 1 NPS NPS 0 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer - automatic transfer from 1gze_2 2c89_4 PROBNOT 1 1 NPS NPS 0 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer - automatic transfer from 1gze_2 2c8a_1 PROBNOT 1 1 NPS NPS 0 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer - automatic transfer from 1gze_2 2c8a_2 PROBNOT 1 1 NPS NPS 0 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer - automatic transfer from 1gze_2 2c8a_3 PROBNOT 1 1 NPS NPS 0 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer - automatic transfer from 1gze_2 2c8a_4 PROBNOT 1 1 NPS NPS 0 12029083 BU changed since last release and is now corrected - Paper implies monomer: Crystals of C3 free of NAD were initially obtained with four independent molecules in the asymmetric unit and diffracted to 2.7 Å resolution. - PISA says monomer - automatic transfer from 1gze_2 2c8o NO 1 1 NPS NPS 16510972 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2c8p NO 1 1 NPS NPS 16510972 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2c8u NO 2 2 C2 C2 16777141 0 - automatic transfer from 1oe8 2c9s PROBNOT 2 2 C2 C2 16406071 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 2c9u PROBNOT 2 2 C2 C2 16406071 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 2c9v PROBNOT 2 2 C2 C2 16406071 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 2ca2 PROBNOT 1 1 NPS NPS 3151020 3151020 9000633 says monomeric -- Annotation transfered from 1uga 2ca8 NO 2 2 C2 C2 16777141 0 - automatic transfer from 1oe8 2cab NO 1 1 NPS NPS 6430186 6430186 10529183 says monomer -- Annotation transfered from 1crm 2cag NO 4 4 D2 D2 8901874 8901874 Interface geometry conserved with 1m7s (40% id) -- Annotation transfered from 1mqf 2cah NO 4 4 D2 D2 7791219 7791219 Interface geometry conserved with 1m7s (40% id) -- Annotation transfered from 1mqf 2cai NO 2 2 C2 C2 16777141 0 - automatic transfer from 1oe8 2cam NO 4 4 D2 D2 9760187 9760187 Avidin is a clear tetramer 2can YES 3 2 NS C2 9309222 9309222 Cannot possibly be this assembly - the active entity is a dimer 2caq NO 2 2 C2 C2 16777141 0 - automatic transfer from 1oe8 2cb5 YES 2 6 NS D3 10404591 10404591 PIsa is right and shows a hexamer in which the interface geometry is conserved with 3gcb (38%) 2cba PROBNOT 1 1 NPS NPS 1433293 1433293 9000633 says monomeric -- Annotation transfered from 1uga 2cbb PROBNOT 1 1 NPS NPS 1433293 1433293 9000633 says monomeric -- Annotation transfered from 1uga 2cbc PROBNOT 1 1 NPS NPS 1433293 1433293 9000633 says monomeric -- Annotation transfered from 1uga 2cbd PROBNOT 1 1 NPS NPS 1433293 1433293 9000633 says monomeric -- Annotation transfered from 1uga 2cbe PROBNOT 1 1 NPS NPS 1433293 1433293 9000633 says monomeric -- Annotation transfered from 1uga 2cbl NA 3 1 C3 NPS 10078535 10078535 Paper does not mention a trimer 2cbp PROBNOT 1 1 NPS NPS 8876647 8876647 Paper says nothing - PISA says monomer 2cbr PROBYES 2 1 NS NPS 10531482 9737849 BU changed since last release and is now incorrect - Said to be a monomer in this paper, which looks at the structure with NMR. However, it was shown that it forms dimers at high [.]. So it is an interesting case: apo and holo forms of CRABPI tend to self-associate at high (1.2 mM) concentrations, while at low concentrations (0.2mM), they are predominantly monomeric (10924105) 2cbs NO 1 1 NPS NPS 10531482 10531482 Apo-CRABPII is largely monomeric in solution -- Annotation transfered from 3cbs 2ccn NO 4 4 D2 D2 16584182 0 Paper says tetramer -- error with the symmetry search? -- four helix bundle ... not very relevant - automatic transfer from 1w5g 2ccp PROBNOT 1 1 NPS NPS 2169873 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 2ccs NA 1 1 NPS NPS 16480864 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automatic transfer from 1uy6 2cct NA 1 1 NPS NPS 16480864 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automatic transfer from 1uy6 2ccu NA 1 1 NPS NPS 16480864 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automatic transfer from 1uy6 2ccw NA 1 1 NPS NPS 16786065 10818345 BU changed since last release and is now corrected - No clear info found - automaticaly inferred from 1dz0 2ccy PROBNOT 2 2 C2 C2 3005592 3005592 SP and PISA say homodimer 2cd0 NO 2 2 C2 C2 10524280 10524280 Classic IgV interaction 2cd2 PROBNOT 1 1 NPS NPS 10194348 10194348 PISA also says monomer - Human is monomeric so I guess it should be - Only Thermogota seems to be dimeric -- Annotation transfered from 1cd2 2cdd_1 NA 1 1 NPS NPS 16460658 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automatic transfer from 1uy6 2cdd_2 NA 1 1 NPS NPS 16460658 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automatic transfer from 1uy6 2cdn PROBNOT 1 1 NPS NPS 16672241 15060080 BU changed since last release and is now corrected - Paper says nothing, PISA says monomeric - automaticaly inferred from 1vkj 2cds NO 1 1 NPS NPS 0 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 2cdt PROBNOT 1 1 NPS NPS 0 15185962 - automatic transfer from 1neg 2cdv PROBNOT 1 1 NPS NPS 6319712 6319712 Paper says nothing, PISA says monomer -- Annotation transfered from 1j0o 2cei NO 24 24 Octa Octa 17070541 9159481 Interface geometry conserved with 1lb3 (53%) - automatic transfer from 2fha 2cej NO 2 2 C2 C2 16509598 9083478 - automatic transfer from 1ajx 2cek PROBYES 1 4 NPS NA 16594661 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 2cel_1 PROBNOT 1 1 NPS NPS 8951380 9466911 None of the papers speaks about a dimer - a dimer is found using PISA but visual inspection reveals a weak interface. - automatic transfer from 6cel 2cel_2 PROBNOT 1 1 NPS NPS 8951380 9466911 None of the papers speaks about a dimer - a dimer is found using PISA but visual inspection reveals a weak interface. - automatic transfer from 6cel 2cem NO 2 2 C2 C2 16509598 9083478 - automatic transfer from 1ajx 2cen NO 2 2 C2 C2 16509598 9083478 - automatic transfer from 1ajx 2cep PROBNOT 1 1 NPS NPS 8038157 0 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 2ceq_1 PROBYES 1 4 NPS D2 17002288 9299327 BU changed since last release and is now incorrect - The enzyme is a tetramer with subunit molecular mass at 60 kDa - automaticaly inferred from 1gow 2ceq_2 PROBYES 1 4 NPS D2 17002288 9299327 BU changed since last release and is now incorrect - The enzyme is a tetramer with subunit molecular mass at 60 kDa - automaticaly inferred from 1gow 2cer_1 PROBYES 1 4 NPS D2 17002288 9299327 BU changed since last release and is now incorrect - The enzyme is a tetramer with subunit molecular mass at 60 kDa - automaticaly inferred from 1gow 2cer_2 PROBYES 1 4 NPS D2 17002288 9299327 BU changed since last release and is now incorrect - The enzyme is a tetramer with subunit molecular mass at 60 kDa - automaticaly inferred from 1gow 2cev_1 YES 6 6 D3 D3 10196128 10196128 Interface geometry conserved with 1gq6 (28%) -- bad interface -- interesting as the geometry of the trimers varies. - automatic transfer from 1cev 2cev_2 YES 6 6 D3 D3 10196128 10196128 Interface geometry conserved with 1gq6 (28%) -- bad interface -- interesting as the geometry of the trimers varies. - automatic transfer from 1cev 2cfd NO 2 2 C2 C2 0 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 2cfg NO 2 2 C2 C2 0 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 2cfk NO 2 2 C2 C2 0 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 2cfl NO 2 2 C2 C2 0 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 2cfw NO 2 2 C2 C2 0 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 2cg0 NO 2 2 C2 C2 0 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 2cg1 NO 2 2 C2 C2 0 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 2cga PROBNOT 2 2 NS NS 4057257 4057257 2cgi NO 1 1 NPS NPS 0 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2cgn PROBYES 1 2 NPS C2 17135241 0 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - 12432100 says: Furthermore, the structure reveals the presence of a FIH-1 homodimer that forms in solution and is essential for FIH activity. - automaticaly inferred from 1h2n 2cgo PROBYES 1 2 NPS C2 17135241 0 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - 12432100 says: Furthermore, the structure reveals the presence of a FIH-1 homodimer that forms in solution and is essential for FIH activity. - automaticaly inferred from 1h2n 2cgu PROBNOT 1 1 NPS NPS 16574416 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2cgv PROBNOT 1 1 NPS NPS 16574416 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2cgw PROBNOT 1 1 NPS NPS 16574416 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2cgx PROBNOT 1 1 NPS NPS 16574416 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2che NO 1 1 NPS NPS 8257674 8257674 CheY is a Mr 14,000 monomeric protein -- Annotation transfered from 1chn 2chf NO 1 1 NPS NPS 8257674 8257674 CheY is a Mr 14,000 monomeric protein -- Annotation transfered from 1chn 2chm PROBNOT 1 1 NPS NPS 16759100 15260978 No info about oligomer in all papers, PISA says monomer - automatic transfer from 1tbf 2chr NO 8 8 D4 D4 15299651 0 Paper says octamer -- Annotation transfered from 1chr 2chs_1 NO 3 3 C3 C3 8378335 8046752 Interface conserved with 1jd1 (0% id) -- Annotation transfered from 1com_1 2chs_2 NO 3 3 C3 C3 8378335 8046752 Interface conserved with 1jd1 (0% id) -- Annotation transfered from 1com_1 2chs_3 NO 3 3 C3 C3 8378335 8046752 Interface conserved with 1jd1 (0% id) -- Annotation transfered from 1com_1 2chs_4 NO 3 3 C3 C3 8378335 8046752 Interface conserved with 1jd1 (0% id) -- Annotation transfered from 1com_1 2cht_1 NO 3 3 C3 C3 8378335 8046752 Interface conserved with 1jd1 (0% id) -- Annotation transfered from 1com_1 2cht_2 NO 3 3 C3 C3 8378335 8046752 Interface conserved with 1jd1 (0% id) -- Annotation transfered from 1com_1 2cht_3 NO 3 3 C3 C3 8378335 8046752 Interface conserved with 1jd1 (0% id) -- Annotation transfered from 1com_1 2cht_4 NO 3 3 C3 C3 8378335 8046752 Interface conserved with 1jd1 (0% id) -- Annotation transfered from 1com_1 2chy NO 1 1 NPS NPS 2645526 2645526 CheY is a Mr 14,000 monomeric protein -- Annotation transfered from 1chn 2ci2 NA 6 6 C6 C6 3828302 3828302 PISA says dodecamer, I dont know: 1ypb which is very similar has a different crystal packing 2ckm PROBYES 2 4 NS NA 16942022 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 2cla PROBNOT 3 3 C3 C3 2271709 2271709 SP says trimer -- PISA very wrong -- Annotation transfered from 3cla 2clx NO 1 1 NPS NPS 17064068 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2cm2 PROBNOT 1 1 NPS NPS 16916797 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2cm3 PROBYES 4 1 C2 NPS 16916797 15817824 BU changed since last release and is now incorrect - Apparently it can also exist in a dimeric form - automaticaly inferred from 1i57 2cm7 PROBNOT 1 1 NPS NPS 16916797 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2cm8 PROBNOT 1 1 NPS NPS 16916797 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2cma PROBNOT 1 1 NPS NPS 16916797 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2cmb PROBNOT 1 1 NPS NPS 16916797 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2cmc PROBNOT 1 1 NPS NPS 16916797 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2cmd NO 2 2 C2 C2 1507230 1507230 Paper says dimer 2cmf PROBYES 2 4 NS NA 16942022 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 2cmm NO 1 1 NPS NPS 8473336 8473336 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2cmo PROBNOT 2 2 C2 C2 16483599 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 2cmy PROBNOT 1 1 NPS NPS 17640870 0 - automatic transfer from 1az8 2cna PROBNOT 4 4 D2 D2 1112816 1112816 -- Annotation transfered from 1cn1 2cnb_1 PROBNOT 2 2 C2 C2 16946458 12615316 BU changed since last release and is now corrected - Paper says dimer - automaticaly inferred from 1gy8 2cnb_2 PROBNOT 2 2 C2 C2 16946458 12615316 BU changed since last release and is now corrected - Paper says dimer - automaticaly inferred from 1gy8 2cne PROBNOT 1 1 NPS NPS 17028182 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2cnf PROBNOT 1 1 NPS NPS 17028182 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2cng PROBNOT 1 1 NPS NPS 17028182 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2cnh PROBNOT 1 1 NPS NPS 17028182 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2cni PROBNOT 1 1 NPS NPS 17028182 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2cp4 PROBNOT 1 1 NPS NPS 1742281 1742281 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 2cpk NO 1 1 NPS NPS 1862342 1862342 two alpha, two beta, alphas do not contact each others -- Annotation transfered from 1jlu 2cpl PROBNOT 1 1 NPS NPS 1453463 1453463 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 2cpp PROBNOT 1 1 NPS NPS 3656428 3656428 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 2crk NO 2 2 C2 C2 9849893 9849893 Paper says: CK plays an important role in the rapid regeneration of ATP in cells where such demands are high. It functions as an 85-kDa dimer 2cro YES 3 1 C3 NPS 2647998 9174359 Apparently monomeric (said in the reference) 2crx YES 4 8 C4 C4 9670032 9670032 BU changed since last release and is now incorrect - -- Annotation transfered from 1kbu 2csc NO 2 2 C2 C2 2043640 2043640 Interface geometry conserved with 1a59 (27%) -- Annotation transfered from 6cts 2csl_1 NO 3 3 C3 C3 0 0 Interface conserved with 1jd1 (50% seq id) 2csl_2 NO 3 3 C3 C3 0 0 Interface conserved with 1jd1 (50% seq id) -- Annotation transfered from 2csl_1 2csn PROBYES 2 1 C2 NPS 8692811 7759525 Origonal paper says nothing - CK1 usually accepted as monomeric (cf paper). 2cst NO 2 2 C2 C2 7897655 7897655 Interface geometry conserved with 2ay6 (34%) 2cth_1 PROBNOT 1 1 NPS NPS -1 1663945 Paper not available, PISA says monomer and family generally monomeric - automatic transfer from 2cym 2cth_2 PROBNOT 1 1 NPS NPS -1 1663945 Paper not available, PISA says monomer and family generally monomeric - automatic transfer from 2cym 2cts NO 2 2 C2 C2 7120407 7120407 Interface geometry conserved with 1a59 (27%) -- Annotation transfered from 6cts 2ctv NO 4 4 D2 D2 -1 0 SP says tetramer -- Annotation transfered from 1cjp 2ctx NA 2 2 C2 C2 1939183 1939183 Ask the persons who work with it 2cv3 PROBNOT 1 1 NPS NPS 16511165 9443341 - automatic transfer from 1c1m 2cvc NO 1 1 NPS NPS 0 12356749 BU changed since last release and is now corrected - 1846136 finds it as a monomer with gel filtration. - automatic transfer from 1h29_4 2cvl_1 NO 3 3 C3 C3 0 0 Interface conserved with 1jd1 (50% seq id) -- Annotation transfered from 2csl_1 2cvl_2 NO 3 3 C3 C3 0 0 Interface conserved with 1jd1 (50% seq id) -- Annotation transfered from 2csl_1 2cvq PROBNOT 2 2 C2 C2 16009341 8471603 SP says dimer - automatic transfer from 1bmd 2cwi_1 NO 1 1 NPS NPS 0 10727216 - automatic transfer from 1qqy 2cwi_2 NO 1 1 NPS NPS 0 10727216 - automatic transfer from 1qqy 2cwj YES 1 3 NPS C3 0 0 Interface conserved with 1jd1 (43% seq id) 2cwt NO 2 2 C2 C2 16566584 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 2cwu NO 2 2 C2 C2 16566584 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 2cwv NO 2 2 C2 C2 16566584 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 2cxb_1 PROBNOT 1 1 NPS NPS 15299423 0 - automatic transfer from 1cxa 2cxb_2 PROBNOT 1 1 NPS NPS 15299423 0 - automatic transfer from 1cxa 2cxg NO 1 1 NPS NPS 7857935 7857935 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric 2cy3 PROBNOT 1 1 NPS NPS 7966289 7966289 Paper not available - PISa says monomer and related prots are monomeric. 2cyh PROBNOT 1 1 NPS NPS 8652512 8652512 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 2cym PROBNOT 1 1 NPS NPS 1663945 1663945 Paper not available, PISA says monomer and family generally monomeric 2cyp PROBNOT 1 1 NPS NPS 6092361 6092361 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 2cyy NA 2 2 C2 C2 0 14976242 BU changed since last release and is now corrected - Paper says it forms disks, but these are not observed in the crystal: it adopts a helical symmetry. - automaticaly inferred from 1ri7 2d01 PROBNOT 1 1 NPS NPS 16533035 15159559 BU changed since last release and is now corrected - Sp says monomer - automaticaly inferred from 1ot9 2d06_1 PROBNOT 1 1 NPS NPS 16221673 12471039 Paper says nothing, PISA says monomer - automatic transfer from 1ls6 2d06_2 PROBNOT 1 1 NPS NPS 16221673 12471039 Paper says nothing, PISA says monomer - automatic transfer from 1ls6 2d10_1 PROBNOT 1 1 NPS NPS 16615918 10970839 May exist in equilibrium between monomers and oligomers: 10893267 - interesting - automatic transfer from 1gc7 2d10_2 PROBNOT 1 1 NPS NPS 16615918 10970839 May exist in equilibrium between monomers and oligomers: 10893267 - interesting - automatic transfer from 1gc7 2d10_3 PROBNOT 1 1 NPS NPS 16615918 10970839 May exist in equilibrium between monomers and oligomers: 10893267 - interesting - automatic transfer from 1gc7 2d10_4 PROBNOT 1 1 NPS NPS 16615918 10970839 May exist in equilibrium between monomers and oligomers: 10893267 - interesting - automatic transfer from 1gc7 2d11_1 PROBNOT 1 1 NPS NPS 16615918 10970839 May exist in equilibrium between monomers and oligomers: 10893267 - interesting - automatic transfer from 1gc7 2d11_2 PROBNOT 1 1 NPS NPS 16615918 10970839 May exist in equilibrium between monomers and oligomers: 10893267 - interesting - automatic transfer from 1gc7 2d11_3 PROBNOT 1 1 NPS NPS 16615918 10970839 May exist in equilibrium between monomers and oligomers: 10893267 - interesting - automatic transfer from 1gc7 2d11_4 PROBNOT 1 1 NPS NPS 16615918 10970839 May exist in equilibrium between monomers and oligomers: 10893267 - interesting - automatic transfer from 1gc7 2d1n_1 PROBNOT 1 1 NPS NPS 16603129 10074939 BU changed since last release and is now corrected - - automaticaly inferred from 456c 2d1n_2 PROBNOT 1 1 NPS NPS 16603129 10074939 BU changed since last release and is now corrected - - automaticaly inferred from 456c 2d1o_1 PROBNOT 1 1 NPS NPS 16603129 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 2d1o_2 PROBNOT 1 1 NPS NPS 16603129 7831311 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme - automatic transfer from 1caq 2d1w NO 2 2 C2 C2 16487484 15323556 Interface geometry conserved with 1ksi (25%) - automatic transfer from 1sii 2d2q_1 PROBNOT 1 1 NPS NPS 16582480 10970839 May exist in equilibrium between monomers and oligomers: 10893267 - interesting - automatic transfer from 1gc7 2d2q_2 PROBNOT 1 1 NPS NPS 16582480 10970839 May exist in equilibrium between monomers and oligomers: 10893267 - interesting - automatic transfer from 1gc7 2d3s_1 YES 2 2 C2 C2 16310781 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. - automatic transfer from 1wbf 2d3s_2 YES 2 2 C2 C2 16310781 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. - automatic transfer from 1wbf 2d3u_1 PROBNOT 1 1 NPS NPS 16828488 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2d3u_2 PROBNOT 1 1 NPS NPS 16828488 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2d3z_1 PROBNOT 1 1 NPS NPS 16828488 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2d3z_2 PROBNOT 1 1 NPS NPS 16828488 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2d41_1 PROBNOT 1 1 NPS NPS 16828488 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2d41_2 PROBNOT 1 1 NPS NPS 16828488 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2d4i_1 NO 1 1 NPS NPS 16552138 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2d4i_2 NO 1 1 NPS NPS 16552138 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2d4j NO 1 1 NPS NPS 16552138 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2d4k_1 NO 1 1 NPS NPS 16552138 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2d4k_2 NO 1 1 NPS NPS 16552138 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2d5i PROBNOT 2 2 C2 C2 16684776 0 - automatic transfer from 1tik 2d6b PROBYES 10 1 NR NPS 16929100 1185784 BU changed since last release and is now incorrect - Lysozyme C is well established as being monomeric - automaticaly inferred from 8lyz 2d6c_1 NO 1 1 NPS NPS 17173408 0 Myoglobin is a monomeric protein (8663546) - automatic transfer from 1a6m 2d6c_2 NO 1 1 NPS NPS 17173408 0 Myoglobin is a monomeric protein (8663546) - automatic transfer from 1a6m 2d8o PROBNOT 1 1 NPS NPS 16510975 10504569 BU changed since last release and is now corrected - Thaumatin is a stable monomeric protein of 22kDa - automaticaly inferred from 1thw 2d8w PROBNOT 1 1 NPS NPS 16510975 0 - automatic transfer from 1az8 2d91 NO 1 1 NPS NPS 16510975 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2daa NO 2 2 C2 C2 -1 0 Homodimer 2dab NO 2 2 C2 C2 9749913 9749913 Homodimer -- Annotation transfered from 2daa 2dap NO 2 2 C2 C2 9521647 9521647 Paper says dimer 2dbv NO 4 4 D2 D2 9175858 9175858 SP says homotetramer - papers too -- Annotation transfered from 1npt 2dc6 NO 1 1 NPS NPS 0 12044902 SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) - automatic transfer from 1ito 2dc7 NO 1 1 NPS NPS 0 12044902 SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) - automatic transfer from 1ito 2dc8 NO 1 1 NPS NPS 0 12044902 SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) - automatic transfer from 1ito 2dc9 NO 1 1 NPS NPS 0 12044902 SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) - automatic transfer from 1ito 2dca NO 1 1 NPS NPS 0 12044902 SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) - automatic transfer from 1ito 2dcb NO 1 1 NPS NPS 0 12044902 SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) - automatic transfer from 1ito 2dcc NO 1 1 NPS NPS 0 12044902 SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) - automatic transfer from 1ito 2dcd NO 1 1 NPS NPS 0 12044902 SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. (here only one chain) - automatic transfer from 1ito 2dcy_1 PROBNOT 1 1 NPS NPS 16467302 0 Paper says nothing and PISA says monomer - automatic transfer from 1xnb 2dcy_2 PROBNOT 1 1 NPS NPS 16467302 0 Paper says nothing and PISA says monomer - automatic transfer from 1xnb 2dcy_3 PROBNOT 1 1 NPS NPS 16467302 0 Paper says nothing and PISA says monomer - automatic transfer from 1xnb 2dcy_4 PROBNOT 1 1 NPS NPS 16467302 0 Paper says nothing and PISA says monomer - automatic transfer from 1xnb 2dcy_5 PROBNOT 1 1 NPS NPS 16467302 0 Paper says nothing and PISA says monomer - automatic transfer from 1xnb 2de8 PROBNOT 1 1 NPS NPS 16820677 9443341 - automatic transfer from 1c1m 2de9 PROBNOT 1 1 NPS NPS 16820677 9443341 - automatic transfer from 1c1m 2dea NO 1 1 NPS NPS 16596389 10413478 Aminopeptidase from Aeromonas proteolytica (AAP) is a small, monomeric enzyme (32KDa) - automatic transfer from 1cp6 2df3 PROBNOT 1 1 NPS NPS 16623661 14747738 Paper doesnt mention a dimer and PISA says monomer - automatic transfer from 1nko 2dfh PROBNOT 1 1 NPS NPS 17510955 11274461 SP says monomer - automatic transfer from 1io2 2dfn PROBNOT 1 1 NPS NPS 17183161 12054870 SP says monomer - automatic transfer from 1l4u 2dfp PROBNOT 2 2 NS NS 10353814 10353814 Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. 2dft PROBYES 4 1 C2 NPS 17183161 12054870 BU changed since last release and is now incorrect - SP says monomer - automaticaly inferred from 1l4u 2dg3 PROBNOT 1 1 NPS NPS 12600203 10425089 BU changed since last release and is now corrected - - automaticaly inferred from 1qpl 2dgc NO 2 2 C2 C2 7500340 7500340 Paper says dimer -- Annotation transfered from 1zil 2dgl NO 6 6 D3 D3 16675957 12912902 Paper says hexamer - automatic transfer from 1pmo 2dgm NO 6 6 D3 D3 16675957 12912902 Paper says hexamer - automatic transfer from 1pmo 2dhc NO 1 1 NPS NPS 8515812 8515812 SP says monomer -- Annotation transfered from 1edb 2dhd NO 1 1 NPS NPS 8515812 8515812 SP says monomer -- Annotation transfered from 1edb 2dhe NO 1 1 NPS NPS 8515812 8515812 SP says monomer -- Annotation transfered from 1edb 2dhf PROBYES 2 1 C2 NPS 2248959 2248959 -- Annotation transfered from 1dhf 2dhq YES 10 12 NS Tetr 10360352 10360352 Paper says dodecamer 2dij NO 1 1 NPS NPS 8672460 8672460 SP says monomer and Cyclodextrin - glycosyltransferases are monomeric -- Annotation transfered from 2cxg 2dik YES 2 2 C2 C2 9753432 9753432 Dimer but wrong interface, the right form is found in 1dik -- problem is PISA does not give the right one 2dkb YES 2 4 C2 D2 8342040 8342040 Identical structures are tetramers and PISA says tetramer for that one. 2dl2 NO 1 1 NPS NPS 10097129 10097129 Paper says monomeric -- Annotation transfered from 1m4k 2dld NO 2 2 C2 C2 0 0 Interface geometry conserved with 2nad (27%) 2dli NO 1 1 NPS NPS 10097129 10097129 Paper says monomeric -- Annotation transfered from 1m4k 2dln YES 1 2 NPS C2 7939684 7939684 Interface geometry conseved with 1ehi (34%) 2dm5 PROBNOT 1 1 NPS NPS 16935302 11316880 Gel filtration performed and no dimer or oligomer mentioned. - automatic transfer from 1i06 2dm6 NO 2 2 C2 C2 16916844 15007077 - automatic transfer from 1v3u 2dnj PROBNOT 2 2 C2 C2 1748997 1748997 BU changed since last release and is now corrected - Either C2 or NPS? 2doo YES 2 1 C2 NPS 16937423 10757977 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says nothing - PISA implies monomer - automaticaly inferred from 1ddk 2dor NO 2 2 C2 C2 9655329 9655329 -- Annotation transfered from 1jub 2dp4 PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1p7v 2dpg NO 2 2 C2 C2 9485426 9485426 -- Annotation transfered from 1e77 2dpz PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2dqk PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1p7v 2dqy PROBYES 3 6 C3 D3 16962139 12725862 BU changed since last release and is now incorrect - exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automaticaly inferred from 1mx1 2dqz PROBYES 3 6 C3 D3 16962139 12725862 BU changed since last release and is now incorrect - exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automaticaly inferred from 1mx1 2dr0 PROBYES 3 6 C3 D3 16962139 12725862 BU changed since last release and is now incorrect - exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automaticaly inferred from 1mx1 2dr5 YES 1 2 NPS C2 17051158 14592988 - automatic transfer from 1ueu 2dr7 YES 1 2 NPS C2 17051158 14592988 - automatic transfer from 1ueu 2dr8 YES 1 2 NPS C2 17051158 14592988 - automatic transfer from 1ueu 2dr9 YES 1 2 NPS C2 17051158 14592988 - automatic transfer from 1ueu 2dra YES 1 2 NPS C2 17051158 14592988 - automatic transfer from 1ueu 2drb YES 1 2 NPS C2 17051158 14592988 - automatic transfer from 1ueu 2drc PROBYES 2 1 C2 NPS 1932031 1932031 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1dds 2dri NO 1 1 NPS NPS 7982928 7982928 ribose ABC transporter, subunit B - monomer according to EcoCyc -- Annotation transfered from 1drj 2ds1 NO 1 1 NPS NPS 16876403 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2dsx PROBNOT 1 1 NPS NPS 16930541 3441010 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes - automatic transfer from 1rdg 2dt0 NO 1 1 NPS NPS 17372347 12529329 Elutes as a monomer - Papers says: The second peak in this final chromatographic step corresponded to a molecular mass of 40 kDa. - automatic transfer from 1ljy 2dt1 NO 1 1 NPS NPS 17372347 12529329 Elutes as a monomer - Papers says: The second peak in this final chromatographic step corresponded to a molecular mass of 40 kDa. - automatic transfer from 1ljy 2dt2 NO 1 1 NPS NPS 17372347 12529329 Elutes as a monomer - Papers says: The second peak in this final chromatographic step corresponded to a molecular mass of 40 kDa. - automatic transfer from 1ljy 2dt3 NO 1 1 NPS NPS 17372347 12529329 Elutes as a monomer - Papers says: The second peak in this final chromatographic step corresponded to a molecular mass of 40 kDa. - automatic transfer from 1ljy 2dtq NO 2 2 C2 C2 17368483 10678837 - automatic transfer from 1dn2 2dtr PROBNOT 2 2 C2 C2 8823163 8823163 -- Annotation transfered from 1fwz 2dts NO 2 2 C2 C2 17368483 10678837 - automatic transfer from 1dn2 2dtw_1 YES 2 2 C2 C2 17057334 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. - automatic transfer from 1wbf 2dtw_2 YES 2 2 C2 C2 17057334 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. - automatic transfer from 1wbf 2dty_1 YES 2 2 C2 C2 17057334 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. - automatic transfer from 1wbf 2dty_2 YES 2 2 C2 C2 17057334 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. - automatic transfer from 1wbf 2du0_1 YES 2 2 C2 C2 17057334 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. - automatic transfer from 1wbf 2du0_2 YES 2 2 C2 C2 17057334 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. - automatic transfer from 1wbf 2du1_1 YES 2 2 C2 C2 17057334 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. - automatic transfer from 1wbf 2du1_2 YES 2 2 C2 C2 17057334 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. - automatic transfer from 1wbf 2dub NO 6 6 D3 D3 9480773 9480773 Everyone says hexamer! 2dud PROBYES 2 4 C2 D2 0 15133161 Given 3ull, this one is probably an error. - automatic transfer from 1s3o 2duj PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1p7v 2duv NO 1 1 NPS NPS 17178224 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2dux NA 1 1 NPS NPS 16952371 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2duz NA 1 1 NPS NPS 16952371 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2dv0 NA 1 1 NPS NPS 16952371 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2dv8 PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2dv9 NO 4 4 C2 C2 17057347 8656429 Paper says tetramer - automatic transfer from 2pel 2dva NO 4 4 C2 C2 17057347 8656429 Paper says tetramer - automatic transfer from 2pel 2dvb NO 4 4 C2 C2 17057347 8656429 Paper says tetramer - automatic transfer from 2pel 2dvd NO 4 4 C2 C2 17057347 8656429 Paper says tetramer - automatic transfer from 2pel 2dvf NO 4 4 C2 C2 17057347 8656429 Paper says tetramer - automatic transfer from 2pel 2dvg NO 4 4 C2 C2 17057347 8656429 Paper says tetramer - automatic transfer from 2pel 2dvi YES 1 2 NPS C2 17051158 14592988 - automatic transfer from 1ueu 2dws NO 3 3 C3 C3 17148448 0 - automatic transfer from 1n70 2dwt NO 3 3 C3 C3 17148448 0 - automatic transfer from 1n70 2dwx_1 PROBNOT 1 1 NPS NPS 17506864 12808037 BU changed since last release and is now corrected - Fragment (150 aa of >600). SP says monomeric - paper says: we do not see any evidence for dimerization in solution by using either gel filtration or dynamic light scattering, suggesting that this is not an in vivo natural dimeric interaction. - automaticaly inferred from 1na8 2dwx_2 PROBNOT 1 1 NPS NPS 17506864 12808037 BU changed since last release and is now corrected - Fragment (150 aa of >600). SP says monomeric - paper says: we do not see any evidence for dimerization in solution by using either gel filtration or dynamic light scattering, suggesting that this is not an in vivo natural dimeric interaction. - automaticaly inferred from 1na8 2dwx_3 PROBNOT 1 1 NPS NPS 17506864 12808037 BU changed since last release and is now corrected - Fragment (150 aa of >600). SP says monomeric - paper says: we do not see any evidence for dimerization in solution by using either gel filtration or dynamic light scattering, suggesting that this is not an in vivo natural dimeric interaction. - automaticaly inferred from 1na8 2dwx_4 PROBNOT 1 1 NPS NPS 17506864 12808037 BU changed since last release and is now corrected - Fragment (150 aa of >600). SP says monomeric - paper says: we do not see any evidence for dimerization in solution by using either gel filtration or dynamic light scattering, suggesting that this is not an in vivo natural dimeric interaction. - automaticaly inferred from 1na8 2dwy_1 PROBNOT 1 1 NPS NPS 17506864 12808037 BU changed since last release and is now corrected - Fragment (150 aa of >600). SP says monomeric - paper says: we do not see any evidence for dimerization in solution by using either gel filtration or dynamic light scattering, suggesting that this is not an in vivo natural dimeric interaction. - automaticaly inferred from 1na8 2dwy_2 PROBNOT 1 1 NPS NPS 17506864 12808037 BU changed since last release and is now corrected - Fragment (150 aa of >600). SP says monomeric - paper says: we do not see any evidence for dimerization in solution by using either gel filtration or dynamic light scattering, suggesting that this is not an in vivo natural dimeric interaction. - automaticaly inferred from 1na8 2dwy_3 PROBNOT 1 1 NPS NPS 17506864 12808037 BU changed since last release and is now corrected - Fragment (150 aa of >600). SP says monomeric - paper says: we do not see any evidence for dimerization in solution by using either gel filtration or dynamic light scattering, suggesting that this is not an in vivo natural dimeric interaction. - automaticaly inferred from 1na8 2dwy_4 PROBNOT 1 1 NPS NPS 17506864 12808037 BU changed since last release and is now corrected - Fragment (150 aa of >600). SP says monomeric - paper says: we do not see any evidence for dimerization in solution by using either gel filtration or dynamic light scattering, suggesting that this is not an in vivo natural dimeric interaction. - automaticaly inferred from 1na8 2dy2 NO 3 3 C3 C3 17148448 0 - automatic transfer from 1n70 2e2c PROBYES 2 1 C2 NPS 10350465 10350465 Paper says: The interaction between particular pairs of E2-C proteins in the crystal has some of the hallmarks of a functional dimer, though solution studies suggest that the E2-C protein exists as a monomer. 2e2h NO 10 10 NPS NPS 17129781 11313498 Correct complex. -- Annotation transfered from 1i3q 2e2i NO 10 10 NPS NPS 17129781 11313498 Correct complex. -- Annotation transfered from 1i3q 2e2j NO 10 10 NPS NPS 17129781 11313498 Correct complex. -- Annotation transfered from 1i3q 2e33_2 PROBNOT 1 1 NPS NPS 17389369 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 2e39 PROBNOT 1 1 NPS NPS 17372351 9038188 Peroxidases seem to be monomeric in general - automatic transfer from 1gza 2e3a PROBNOT 1 1 NPS NPS 17372351 9038188 Peroxidases seem to be monomeric in general - automatic transfer from 1gza 2e3b PROBNOT 1 1 NPS NPS 17372351 9038188 Peroxidases seem to be monomeric in general - automatic transfer from 1gza 2e6y NO 2 2 C2 C2 17290979 12011084 SP says dimer - interface geometry conserved with 1q6q (26%) - automatic transfer from 1lor 2e7q_1 YES 2 2 C2 C2 17510954 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. - automatic transfer from 1wbf 2e7q_2 YES 2 2 C2 C2 17510954 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. - automatic transfer from 1wbf 2e7t_1 YES 2 2 C2 C2 17510954 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. - automatic transfer from 1wbf 2e7t_2 YES 2 2 C2 C2 17510954 10089310 Paper says it is a dimeric lectin but the wrong interface is being used in this reconstruction. - automatic transfer from 1wbf 2ebn PROBNOT 1 1 NPS NPS 7947807 7947807 SP says monomer 2eck_1 PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP and EcoCyc say monomer - automaticaly inferred from 1e4y 2eck_2 PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP and EcoCyc say monomer - automaticaly inferred from 1e4y 2ecp NO 2 2 C2 C2 10220320 10220320 2eda NO 1 1 NPS NPS 8369276 8369276 SP says monomer -- Annotation transfered from 1edb 2edc NO 1 1 NPS NPS 8369276 8369276 SP says monomer -- Annotation transfered from 1edb 2eft PROBNOT 2 2 C2 C2 17524982 12502353 BU changed since last release and is now corrected - - automaticaly inferred from 1mzs 2eip NO 6 6 D3 D3 15299678 0 SP and EcoCyc say hexamer -- Annotation transfered from 1mjz 2ejn PROBYES 2 1 C2 NPS 0 12851385 BU changed since last release and is now incorrect - Paper says: Herein, we report the crystal structure of recombinant monomeric Fel d 1 at 1.85-A resolution - automaticaly inferred from 1puo 2emd PROBNOT 2 2 C2 C2 9145105 9145105 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 2emo 2emn PROBNOT 2 2 C2 C2 9145105 9145105 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 2emo 2emo PROBNOT 2 2 C2 C2 9145105 9145105 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium 2enb NO 1 1 NPS NPS 8025105 8025105 Paper says monomeric -- Annotation transfered from 1ena 2enr NO 4 4 D2 D2 11092923 11092923 SP says tetramer -- Annotation transfered from 1cjp 2epe NO 1 1 NPS NPS 0 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2eql NO 1 1 NPS NPS 1569037 1569037 2er0 PROBNOT 1 1 NPS NPS 2690945 2690945 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 2er6 PROBNOT 1 1 NPS NPS 3119339 3119339 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 2er7 PROBNOT 1 1 NPS NPS 2266553 2266553 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 2er9 PROBNOT 1 1 NPS NPS 2690945 2690945 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 2era NA 1 1 NPS NPS 10691969 10691969 All papers are useless impossible to find an answer %$@~# -- Annotation transfered from 5ebx 2erk PROBNOT 1 1 NPS NPS 9298898 9298898 -- Annotation transfered from 4erk 2erz NO 1 1 NPS NPS 16249185 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 2es2 PROBNOT 1 1 NPS NPS 16780871 7703860 The difference in the self-association of CspB in the presence and absence of phosphate was supported by size-exclusion chromatography - phosphate-induced dimerization - automatic transfer from 1csq 2est PROBNOT 1 1 NPS NPS 6926029 6926029 -- Annotation transfered from 1c1m 2etf_1 PROBNOT 1 1 NPS NPS 0 10932255 Paper says nothing, PISA says monomer - automatic transfer from 1f82 2etf_2 PROBNOT 1 1 NPS NPS 0 10932255 Paper says nothing, PISA says monomer - automatic transfer from 1f82 2etm_1 PROBNOT 1 1 NPS NPS 0 12467573 Paper says nothing about a oligomer, PISA says monomer - automatic transfer from 1mp8 2etm_2 PROBNOT 1 1 NPS NPS 0 12467573 Paper says nothing about a oligomer, PISA says monomer - automatic transfer from 1mp8 2eu2 PROBNOT 1 1 NPS NPS 16820676 8987974 9000633 says monomeric - automatic transfer from 1uga 2eu3 PROBNOT 1 1 NPS NPS 16820676 8987974 9000633 says monomeric - automatic transfer from 1uga 2euh NO 4 4 D2 D2 10388564 10388564 Interface geometry conserved with 1uxr (35%) -- Annotation transfered from 1qi6 2eun PROBNOT 1 1 NPS NPS 16490206 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 2euo PROBNOT 1 1 NPS NPS 16490206 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 2eup PROBNOT 1 1 NPS NPS 16490206 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 2euq PROBNOT 1 1 NPS NPS 16490206 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 2eur PROBNOT 1 1 NPS NPS 16490206 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 2eus PROBNOT 1 1 NPS NPS 16490206 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 2eut PROBNOT 1 1 NPS NPS 16490206 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 2euu PROBNOT 1 1 NPS NPS 16490206 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 2ev0 NO 2 2 C2 C2 16533030 12847518 Interface geometry conserved down to 30% with 1b1b - automatic transfer from 1on1 2ev5 NO 2 2 C2 C2 16533030 12847518 Interface geometry conserved down to 30% with 1b1b - automatic transfer from 1on1 2ev6 NO 2 2 C2 C2 16533030 12847518 Interface geometry conserved down to 30% with 1b1b - automatic transfer from 1on1 2evk NO 1 1 NPS NPS 16519512 0 Myoglobin is a monomeric protein (8663546) - automatic transfer from 1a6m 2evp NO 1 1 NPS NPS 16519512 0 Myoglobin is a monomeric protein (8663546) - automatic transfer from 1a6m 2ewa PROBNOT 1 1 NPS NPS 16374788 11896401 - automatic transfer from 1kv1 2ewb NO 6 6 D3 D3 16519517 8357796 Interface geometry conserved with 1gyt (30%) - automatic transfer from 1bll 2ewp_1 NO 2 2 C2 C2 16307879 11864604 Paper says dimer - automatic transfer from 1kv6 2ewp_2 NO 2 2 C2 C2 16307879 11864604 Paper says dimer - automatic transfer from 1kv6 2ewp_3 NO 2 2 C2 C2 16307879 11864604 Paper says dimer - automatic transfer from 1kv6 2exc PROBNOT 1 1 NPS NPS 0 12954329 - automatic transfer from 1pmv 2exl NA 2 1 C2 NPS 0 12970348 BU changed since last release and is now incorrect - Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automaticaly inferred from 1qy5 2exm NO 1 1 NPS NPS 7479711 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2exo PROBNOT 1 1 NPS NPS 7918478 7918478 Apparently the family doesnt form dimers but there is no clear evidence. -- Annotation transfered from 1exp 2ez4 NO 4 4 D2 D2 16680160 8145244 Interface geometry conserved with 1ovm (23%) - automatic transfer from 1pow 2ez7 PROBNOT 1 1 NPS NPS 16807956 8987974 9000633 says monomeric - automatic transfer from 1uga 2ez8 NO 4 4 D2 D2 16680160 8145244 Interface geometry conserved with 1ovm (23%) - automatic transfer from 1pow 2ez9 NO 4 4 D2 D2 16680160 8145244 Interface geometry conserved with 1ovm (23%) - automatic transfer from 1pow 2ezt NO 4 4 D2 D2 16680160 8145244 Interface geometry conserved with 1ovm (23%) - automatic transfer from 1pow 2ezu NO 4 4 D2 D2 16680160 8145244 Interface geometry conserved with 1ovm (23%) - automatic transfer from 1pow 2f01 NO 4 4 D2 D2 16699183 9148939 BU changed since last release and is now corrected - - automatic transfer from 1vwl 2f14 PROBNOT 1 1 NPS NPS 16787097 8987974 9000633 says monomeric - automatic transfer from 1uga 2f1g_1 PROBNOT 1 1 NPS NPS 16446091 12641451 SP says monomer - automatic transfer from 1nqc 2f1g_2 PROBNOT 1 1 NPS NPS 16446091 12641451 SP says monomer - automatic transfer from 1nqc 2f1o_1 NO 2 2 C2 C2 0 11587640 BU changed since last release and is now corrected - - automatic transfer from 1h66_2 2f1o_2 NO 2 2 C2 C2 0 11587640 BU changed since last release and is now corrected - - automatic transfer from 1h66_2 2f1o_3 NO 2 2 C2 C2 0 11587640 BU changed since last release and is now corrected - - automatic transfer from 1h66_2 2f1o_4 NO 2 2 C2 C2 0 11587640 BU changed since last release and is now corrected - - automatic transfer from 1h66_2 2f21 PROBYES 1 2 NPS C2 16807295 10932246 Dimer according to PISA, and also according to me given the interface between the 2 polyp. chains in the ASU. But apparently no biochemical evidence. - automatic transfer from 1f8a 2f2k NA 1 1 NPS NPS 16639747 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2f2n NO 1 1 NPS NPS 16600702 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2f2v PROBNOT 1 1 NPS NPS 0 15185962 - automatic transfer from 1neg 2f30 NO 1 1 NPS NPS 16600702 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2f38 PROBNOT 1 1 NPS NPS 16475787 14996743 PISA says it is a monomer, and relative are too. - automatic transfer from 1s1r 2f3b PROBNOT 4 4 D2 D2 0 12595529 BU changed since last release and is now corrected - - automaticaly inferred from 1nv6 2f3d PROBNOT 4 4 D2 D2 0 12595529 BU changed since last release and is now corrected - - automaticaly inferred from 1nv6 2f3g PROBNOT 2 2 C2 C2 9405042 9405042 Paper says: IIAGlc aggregates in solution; dimeric, trimeric, and hexameric forms of IIAGlc have been observed in gel filtration and immunoelectrophoretic studies (40). The dimeric and trimeric crystal contact interactions shown in Figure 2b,c are likely to represent the states observed in these studies. - Interface conserved with 1gpr (42%) 2f3h PROBNOT 4 4 D2 D2 0 12595529 BU changed since last release and is now corrected - - automaticaly inferred from 1nv6 2f3p PROBYES 2 2 C2 C2 16464598 9384557 Wrong interface of the dimer - automatic transfer from 2amv 2f3q PROBYES 2 2 C2 C2 16464598 9384557 Wrong interface of the dimer - automatic transfer from 2amv 2f3r PROBYES 6 2 D3 C2 16690197 0 BU changed since last release and is now incorrect - SP says: Homotetramer (under low ionic conditions) or homodimer (under high ionic conditions). - automaticaly inferred from 1s96 2f3s PROBYES 2 2 C2 C2 16464598 9384557 Wrong interface of the dimer - automatic transfer from 2amv 2f3t PROBYES 6 2 D3 C2 16690197 0 BU changed since last release and is now incorrect - SP says: Homotetramer (under low ionic conditions) or homodimer (under high ionic conditions). - automaticaly inferred from 1s96 2f3u PROBYES 2 2 C2 C2 16464598 9384557 Wrong interface of the dimer - automatic transfer from 2amv 2f48 PROBNOT 2 2 C2 C2 0 12015149 Paper says dimer - automatic transfer from 1kzh 2f4a NO 1 1 NPS NPS 16600702 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2f4b_1 PROBYES 1 2 NPS C2 16451087 15258145 PISA says homodimer and identicals are homodimers - automatic transfer from 1wm0 2f4b_2 PROBYES 1 2 NPS C2 16451087 15258145 PISA says homodimer and identicals are homodimers - automatic transfer from 1wm0 2f4g NO 1 1 NPS NPS 16600702 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2f4y_1 YES 1 3 NPS C3 16600702 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 2f4y_2 YES 1 3 NPS C3 16600702 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 2f4y_3 YES 1 3 NPS C3 16600702 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 2f56_1 YES 1 3 NPS C3 16600702 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 2f56_2 YES 1 3 NPS C3 16600702 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 2f56_3 YES 1 3 NPS C3 16600702 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 2f5c NO 2 2 C2 C2 16533030 12847518 Interface geometry conserved down to 30% with 1b1b - automatic transfer from 1on1 2f5d NO 2 2 C2 C2 16533030 12847518 Interface geometry conserved down to 30% with 1b1b - automatic transfer from 1on1 2f5e NO 2 2 C2 C2 16533030 12847518 Interface geometry conserved down to 30% with 1b1b - automatic transfer from 1on1 2f5f NO 2 2 C2 C2 16533030 12847518 Interface geometry conserved down to 30% with 1b1b - automatic transfer from 1on1 2f5i NO 2 2 C2 C2 0 0 Same dimer as 2b3u 2f5m_1 YES 1 3 NPS C3 16600702 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 2f5m_2 YES 1 3 NPS C3 16600702 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 2f5m_3 YES 1 3 NPS C3 16600702 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 2f5q PROBNOT 1 1 NPS NPS 16497933 9224623 Paper says: DNA glycosylases are relatively small monomeric proteins that do not require cofactors for their activity, - automatic transfer from 1r2y 2f5s PROBNOT 1 1 NPS NPS 16497933 9224623 Paper says: DNA glycosylases are relatively small monomeric proteins that do not require cofactors for their activity, - automatic transfer from 1r2y 2f5w_1 YES 1 3 NPS C3 16600702 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 2f5w_2 YES 1 3 NPS C3 16600702 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 2f5w_3 YES 1 3 NPS C3 16600702 9927651 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Paper says trimer - domain swapped - automaticaly inferred from 1yvs 2f69 PROBNOT 1 1 NPS NPS 16415881 12372304 Paper says all SET proteins are monomeric - automatic transfer from 1muf 2f6t PROBNOT 1 1 NPS NPS 16386905 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2f6v PROBNOT 1 1 NPS NPS 16386905 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2f6w PROBNOT 1 1 NPS NPS 16386905 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2f6y PROBNOT 1 1 NPS NPS 16386905 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2f6z PROBNOT 1 1 NPS NPS 16386905 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2f70 PROBNOT 1 1 NPS NPS 16386905 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2f71 PROBNOT 1 1 NPS NPS 16386905 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2f7d NO 1 1 NPS NPS 0 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 2f7e NO 1 1 NPS NPS 16413780 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 2f7i NO 4 4 D2 D2 14711308 11106758 - automatic transfer from 1g1o 2f7x NO 1 1 NPS NPS 16403626 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 2f7z NO 1 1 NPS NPS 16413780 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 2f8f NO 2 2 C2 C2 16777141 0 - automatic transfer from 1oe8 2f8i PROBYES 2 4 C2 D2 12820260 11106758 BU changed since last release and is now incorrect - - automaticaly inferred from 1g1o 2f8j_1 NO 2 2 C2 C2 0 0 - automatic transfer from 1uu2 2f8j_2 NO 2 2 C2 C2 0 0 - automatic transfer from 1uu2 2f90 NO 2 2 C2 C2 17052986 15258155 11038361 and SP say dimer - automatic transfer from 1t8p 2fal NO 1 1 NPS NPS 8411158 8411158 Myoglobin is well known to be monomeric 2fam NO 1 1 NPS NPS 8411158 8411158 Myoglobin is well known to be monomeric -- Annotation transfered from 2fal 2fap_1 PROBNOT 1 1 NPS NPS 10089303 10425089 BU changed since last release and is now corrected - - automaticaly inferred from 1qpl 2fax PROBNOT 1 1 NPS NPS 9063874 9063874 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 2fdx 2fbb NO 1 1 NPS NPS 16552135 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2fbp NO 4 4 D2 D2 2157849 2157849 -- Annotation transfered from 1eyi 2fbr NO 4 4 D2 D2 0 11106758 - automatic transfer from 1g1o 2fbz NO 2 2 C2 C2 16489746 12220171 Paper says dimer - similar to mamamlian ones - interesting for conservation as many species available - automatic transfer from 1m7z 2fc1 NO 2 2 C2 C2 16489746 12220171 Paper says dimer - similar to mamamlian ones - interesting for conservation as many species available - automatic transfer from 1m7z 2fcb NO 1 1 NPS NPS 10064577 10064577 We showed that FcgRII is monomeric in solution as proven by size exclusion chromatography of both baculo-derived, thus glycosylated, and E. coli material and conclude that the previously observed dimer originates from the requirements of crystal packing. -- Annotation transfered from 1h9v 2fcr PROBNOT 1 1 NPS NPS 1602481 1602481 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins 2fd2 NO 1 1 NPS NPS 1939185 1939185 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 2fd7 PROBNOT 1 1 NPS NPS 0 8450543 Although no clear reference was found, it is accepted to me that crambin is at least predominantly monomeric in somution. -- this family is a MESSSS - automatic transfer from 1cbn 2fd9 PROBNOT 1 1 NPS NPS 0 8450543 Although no clear reference was found, it is accepted to me that crambin is at least predominantly monomeric in somution. -- this family is a MESSSS - automatic transfer from 1cbn 2fde NO 2 2 C2 C2 16458505 9083478 - automatic transfer from 1ajx 2fdn PROBNOT 1 1 NPS NPS 9405040 9405040 No info, PISA says monomer -- Annotation transfered from 1fdn 2fdx PROBNOT 1 1 NPS NPS 9063874 9063874 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins 2fe6 PROBNOT 1 1 NPS NPS 16510191 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 2fer PROBNOT 1 1 NPS NPS 16510191 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 2fet PROBYES 2 2 C2 C2 0 9384557 Wrong interface of the dimer - automatic transfer from 2amv 2feu_1 PROBNOT 1 1 NPS NPS 16510191 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 2feu_2 PROBNOT 1 1 NPS NPS 16510191 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 2ff1 NO 2 2 C2 C2 16630632 11292348 Paper says dimer: The T. vivax IAG-NH is a homodimer, with each subunit consisting of ten beta-strands, 12 alpha-helices and three small 3(10)-helices. - We estimated the apparent molecular mass of the active nucleoside hydrolase from T. vivax using gel chromatography on a 10/30 Superdex-200 HR column. The enzyme elutes with a distribution coefficient (Kd in equation (1)) of 0.42 corresponding to a calculated molecular mass of 59,600 Da. Denaturing polyacrylamide gel electrophoresis gave a single band with a subunit molecular mass of approximately 35,000 Da, consistent with the predicted subunit molecular mass of 37,584 Da. - automatic transfer from 1hoz 2ff2 NO 2 2 C2 C2 16630632 11292348 Paper says dimer: The T. vivax IAG-NH is a homodimer, with each subunit consisting of ten beta-strands, 12 alpha-helices and three small 3(10)-helices. - We estimated the apparent molecular mass of the active nucleoside hydrolase from T. vivax using gel chromatography on a 10/30 Superdex-200 HR column. The enzyme elutes with a distribution coefficient (Kd in equation (1)) of 0.42 corresponding to a calculated molecular mass of 59,600 Da. Denaturing polyacrylamide gel electrophoresis gave a single band with a subunit molecular mass of approximately 35,000 Da, consistent with the predicted subunit molecular mass of 37,584 Da. - automatic transfer from 1hoz 2ff5 PROBYES 2 2 C2 C2 0 9384557 Wrong interface of the dimer - automatic transfer from 2amv 2ff7 PROBNOT 1 1 NPS NPS 16858415 12823972 Paper says: we suggest that this conformation may represent a latent monomeric form of the NBD. - non-native state (normally homodimeric). - automatic transfer from 1mt0 2ffn PROBNOT 1 1 NPS NPS -1 14581238 Paper says nothing, PISA says monomer - automatic transfer from 1j0o 2ffy_1 PROBNOT 1 1 NPS NPS 16506777 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 2ffy_2 PROBNOT 1 1 NPS NPS 16506777 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 2fg6_1 PROBNOT 3 3 C3 C3 0 12095263 Paper says trimer - automatic transfer from 1js1 2fg6_2 PROBNOT 3 3 C3 C3 0 12095263 Paper says trimer - automatic transfer from 1js1 2fg7_1 PROBNOT 3 3 C3 C3 0 12095263 Paper says trimer - automatic transfer from 1js1 2fg7_2 PROBNOT 3 3 C3 C3 0 12095263 Paper says trimer - automatic transfer from 1js1 2fgb PROBNOT 1 1 NPS NPS 0 14996743 PISA says it is a monomer, and relative are too. - automatic transfer from 1s1r 2fgf PROBNOT 1 1 NPS NPS 1849658 1849658 SP says monomer -- Annotation transfered from 1bas 2fgi PROBYES 2 1 C2 NPS 9774334 9774334 Paper does not mention dimer and PISA says monomer 2fha NO 24 24 Octa Octa 9159481 9159481 Interface geometry conserved with 1lb3 (53%) 2fhe NO 2 2 C2 C2 9367777 9367777 2fht PROBYES 1 2 NPS C2 17243149 11041848 BU changed since last release and is now incorrect - vMIP-II is a monomer at millimolar concentrations - but the dimer is similar in related proteins so it is relevant. - automaticaly inferred from 1cm9 2fib PROBNOT 1 1 NPS NPS 9207064 9016719 BU changed since last release and is now corrected - Paper doesnt speak about this dimer - automaticaly inferred from 1fic 2fiv NO 2 2 C2 C2 9271500 9271500 -- Annotation transfered from 3fiv 2fj2_1 PROBNOT 2 2 C2 C2 17243149 11041848 vMIP-II is a monomer at millimolar concentrations - but the dimer is similar in related proteins so it is relevant. - automatic transfer from 1cm9 2fj2_2 PROBNOT 2 2 C2 C2 17243149 11041848 vMIP-II is a monomer at millimolar concentrations - but the dimer is similar in related proteins so it is relevant. - automatic transfer from 1cm9 2fjp NO 2 2 C2 C2 16759103 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2fjs NO 3 3 C3 C3 17227014 9353305 - automatic transfer from 1as7 2fjv PROBYES 2 1 C2 NPS 16771498 10669612 BU changed since last release and is now incorrect - - automatic transfer from 1qai 2fjw PROBYES 2 1 C2 NPS 16771498 10669612 BU changed since last release and is now incorrect - - automatic transfer from 1qai 2fjx PROBYES 2 1 C2 NPS 16771498 10669612 BU changed since last release and is now incorrect - - automatic transfer from 1qai 2fjy_1 PROBNOT 1 1 NPS NPS 16111659 10662696 BU changed since last release and is now corrected - - automaticaly inferred from 1dqe 2fjy_2 PROBNOT 1 1 NPS NPS 16111659 10662696 BU changed since last release and is now corrected - - automaticaly inferred from 1dqe 2fka PROBNOT 1 1 NPS NPS 16674976 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 2fke YES 2 1 C2 NPS 7684380 10852943 Normally monomeric in solution - But very interesting: one mutation (F36M) transforms it into an inducible dimer. Isnt that so interesting? It thus also shows that it can be very simple to form a heterointerfaces, and that a high proportion of supposedly errors in the BU can reflect a potential high affinity (given that 1/2 mutations are introduced) - very nice example! 2fko PROBNOT 3 3 C3 C3 0 0 No info but this fold has the active site at the interface of the trimer - - automatic transfer from 1v3w 2fky_1 PROBNOT 1 1 NPS NPS 16439123 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2fky_2 PROBNOT 1 1 NPS NPS 16439123 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2fl2_1 PROBNOT 1 1 NPS NPS 16439123 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2fl2_2 PROBNOT 1 1 NPS NPS 16439123 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2fl6_1 PROBNOT 1 1 NPS NPS 16439123 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2fl6_2 PROBNOT 1 1 NPS NPS 16439123 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2flk PROBNOT 1 1 NPS NPS 16674976 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 2flm NO 4 4 D2 D2 14583036 11106758 - automatic transfer from 1g1o 2flv PROBNOT 1 1 NPS NPS 9063874 9063874 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 2fdx 2flw PROBNOT 1 1 NPS NPS 16674976 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 2fm0 PROBNOT 4 4 D2 D2 16539372 12842049 the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automatic transfer from 1oyn 2fm1 NO 4 4 D2 D2 0 12269813 - automatic transfer from 1m6s 2fm5 PROBNOT 4 4 D2 D2 16539372 12842049 the crystallographic and biochemical studies suggest that either monomer, dimer, or tetramer may be catalytically active, depending on the isoforms of the enzyme. -- interesting family to look at the evolution of oligomeric state - automatic transfer from 1oyn 2fm6_1 YES 1 4 NPS D2 0 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automatic transfer from 1sml 2fm6_2 YES 1 4 NPS D2 0 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automatic transfer from 1sml 2fme_1 PROBNOT 1 1 NPS NPS 16458511 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2fme_2 PROBNOT 1 1 NPS NPS 16458511 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2fmf PROBNOT 1 1 NPS NPS 16674976 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 2fmg PROBNOT 1 1 NPS NPS 16686544 8987974 9000633 says monomeric - automatic transfer from 1uga 2fmh PROBNOT 1 1 NPS NPS 16674976 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 2fmi PROBNOT 1 1 NPS NPS 16674976 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 2fmk PROBNOT 1 1 NPS NPS 16674976 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 2fmx_1 PROBYES 1 2 NPS C2 16899220 11739406 BU changed since last release and is now incorrect - The protein had a native apparent molecular mass of 43.6 kD corresponding to a dimer - automaticaly inferred from 1f6b 2fmx_2 PROBYES 1 2 NPS C2 16899220 11739406 BU changed since last release and is now incorrect - The protein had a native apparent molecular mass of 43.6 kD corresponding to a dimer - automaticaly inferred from 1f6b 2fmz PROBNOT 1 1 NPS NPS 16686544 8987974 9000633 says monomeric - automatic transfer from 1uga 2fn3 NO 4 4 D2 D2 0 9665697 Interface geometry conserved with 1ovm (25%) - automatic transfer from 1bfd 2fnx PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2fo0 PROBNOT 1 1 NPS NPS 16543148 12654251 Dimer not mentioned in the paper - PISA says dimer? - automatic transfer from 1opk 2fo9 PROBNOT 1 1 NPS NPS 16488429 9443341 - automatic transfer from 1c1m 2foa PROBNOT 1 1 NPS NPS 16488429 9443341 - automatic transfer from 1c1m 2fob PROBNOT 1 1 NPS NPS 16488429 9443341 - automatic transfer from 1c1m 2foc PROBNOT 1 1 NPS NPS 16488429 9443341 - automatic transfer from 1c1m 2fod PROBNOT 1 1 NPS NPS 16488429 9443341 - automatic transfer from 1c1m 2foe PROBNOT 1 1 NPS NPS 16488429 9443341 - automatic transfer from 1c1m 2fof PROBNOT 1 1 NPS NPS 16488429 9443341 - automatic transfer from 1c1m 2fog PROBNOT 1 1 NPS NPS 16488429 9443341 - automatic transfer from 1c1m 2foh PROBNOT 1 1 NPS NPS 16488429 9443341 - automatic transfer from 1c1m 2foq PROBNOT 1 1 NPS NPS 16506782 8987974 9000633 says monomeric - automatic transfer from 1uga 2fos PROBNOT 1 1 NPS NPS 16506782 8987974 9000633 says monomeric - automatic transfer from 1uga 2fou PROBNOT 1 1 NPS NPS 16506782 8987974 9000633 says monomeric - automatic transfer from 1uga 2fov PROBNOT 1 1 NPS NPS 16506782 8987974 9000633 says monomeric - automatic transfer from 1uga 2fox PROBNOT 1 1 NPS NPS 9063874 9063874 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 2fdx 2foy_1 NO 1 1 NPS NPS 16506782 0 10529183 says monomer - automatic transfer from 1crm 2foy_2 NO 1 1 NPS NPS 16506782 0 10529183 says monomer - automatic transfer from 1crm 2fpz NO 4 4 D2 D2 16681368 9521329 The paper shows tha tit is a tetramer. In addition, it is would be active only as a tetramer - automatic transfer from 1a0l 2fq6 PROBNOT 4 4 D2 D2 17300162 8831789 - automatic transfer from 1cl1 2fq9_1 PROBNOT 1 1 NPS NPS 0 12641451 SP says monomer - automatic transfer from 1nqc 2fq9_2 PROBNOT 1 1 NPS NPS 0 12641451 SP says monomer - automatic transfer from 1nqc 2fqd PROBNOT 1 1 NPS NPS 17217912 12794077 Paper says nothing, PISA says monomer - automatic transfer from 1n68 2fqe PROBNOT 1 1 NPS NPS 17217912 12794077 Paper says nothing, PISA says monomer - automatic transfer from 1n68 2fqf PROBNOT 1 1 NPS NPS 17217912 12794077 Paper says nothing, PISA says monomer - automatic transfer from 1n68 2fqg PROBNOT 1 1 NPS NPS 17217912 12794077 Paper says nothing, PISA says monomer - automatic transfer from 1n68 2fql NO 3 3 C3 C3 17027502 17027502 Paper says trimer - note that the trimer also forms higher order assemblies (24-mers) 2fqo NO 2 2 C2 C2 16686542 11553770 - automatic transfer from 1ie0 2fqt NO 2 2 C2 C2 16686542 11553770 - automatic transfer from 1ie0 2fr3 PROBNOT 1 1 NPS NPS 16979656 9737849 BU changed since last release and is now corrected - Apo-CRABPII is largely monomeric in solution - automaticaly inferred from 1xca 2fra_1 PROBNOT 1 1 NPS NPS 0 12641451 SP says monomer - automatic transfer from 1nqc 2fra_2 PROBNOT 1 1 NPS NPS 0 12641451 SP says monomer - automatic transfer from 1nqc 2frf NO 1 1 NPS NPS 16777231 11935353 Myoglobin is well known to be monomeric - automatic transfer from 1gjn 2fri NO 1 1 NPS NPS 16777231 11935353 Myoglobin is well known to be monomeric - automatic transfer from 1gjn 2frj NO 1 1 NPS NPS 16777231 11935353 Myoglobin is well known to be monomeric - automatic transfer from 1gjn 2frk NO 1 1 NPS NPS 16777231 11935353 Myoglobin is well known to be monomeric - automatic transfer from 1gjn 2frq_1 PROBNOT 1 1 NPS NPS 0 12641451 SP says monomer - automatic transfer from 1nqc 2frq_2 PROBNOT 1 1 NPS NPS 0 12641451 SP says monomer - automatic transfer from 1nqc 2frz_1 PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 2frz_2 PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 2fs2 PROBNOT 4 4 D2 D2 16464851 16464851 BU changed since last release and is now corrected - masses determined by gel filtration chromatography correspond to 67 kDa and 58kDa. Both PaaIs are therefore homotetramers. (PISA wrong - says dimer) - automaticaly inferred from 1psu 2fs6_1 PROBNOT 1 1 NPS NPS 16979656 9737849 BU changed since last release and is now corrected - Apo-CRABPII is largely monomeric in solution - automaticaly inferred from 1xca 2fs6_2 PROBNOT 1 1 NPS NPS 16979656 9737849 BU changed since last release and is now corrected - Apo-CRABPII is largely monomeric in solution - automaticaly inferred from 1xca 2fs7_1 PROBNOT 1 1 NPS NPS 16979656 9737849 BU changed since last release and is now corrected - Apo-CRABPII is largely monomeric in solution - automaticaly inferred from 1xca 2fs7_2 PROBNOT 1 1 NPS NPS 16979656 9737849 BU changed since last release and is now corrected - Apo-CRABPII is largely monomeric in solution - automaticaly inferred from 1xca 2fs8 NO 4 4 D2 D2 16681368 9521329 The paper shows tha tit is a tetramer. In addition, it is would be active only as a tetramer - automatic transfer from 1a0l 2fs9 NO 4 4 D2 D2 16681368 9521329 The paper shows tha tit is a tetramer. In addition, it is would be active only as a tetramer - automatic transfer from 1a0l 2ft2_1 PROBNOT 1 1 NPS NPS 0 12641451 SP says monomer - automatic transfer from 1nqc 2ft2_2 PROBNOT 1 1 NPS NPS 0 12641451 SP says monomer - automatic transfer from 1nqc 2ftd_1 NO 1 1 NPS NPS 0 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 2ftd_2 NO 1 1 NPS NPS 0 10074491 Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa - automatic transfer from 1atk 2ftq PROBNOT 2 2 C2 C2 0 10648646 BU changed since last release and is now corrected - Clear dimer - automaticaly inferred from 1qqq 2fts NO 2 2 C2 C2 16511563 15201864 Interface geometry conserved with 1uz5 (32%) - automatic transfer from 1t3e 2fu3 NO 2 2 C2 C2 16511563 15201864 Interface geometry conserved with 1uz5 (32%) - automatic transfer from 1t3e 2fu6_1 YES 1 4 NPS D2 0 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automatic transfer from 1sml 2fu6_2 YES 1 4 NPS D2 0 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automatic transfer from 1sml 2fu7_1 YES 1 4 NPS D2 0 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automatic transfer from 1sml 2fu7_2 YES 1 4 NPS D2 0 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automatic transfer from 1sml 2fu8_1 YES 1 4 NPS D2 0 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automatic transfer from 1sml 2fu8_2 YES 1 4 NPS D2 0 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automatic transfer from 1sml 2fu9_1 YES 1 4 NPS D2 0 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automatic transfer from 1sml 2fu9_2 YES 1 4 NPS D2 0 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automatic transfer from 1sml 2fua NO 4 4 C4 C4 15299567 0 -- Annotation transfered from 1e4a 2fud_1 PROBNOT 1 1 NPS NPS 0 12641451 SP says monomer - automatic transfer from 1nqc 2fud_2 PROBNOT 1 1 NPS NPS 0 12641451 SP says monomer - automatic transfer from 1nqc 2fum_1 PROBNOT 1 1 NPS NPS 16674948 12551895 A further step of gel filtration in a Superdex 75 column was performed to separate the monomeric protein from aggregated material. - automatic transfer from 1o6y 2fum_2 PROBNOT 1 1 NPS NPS 16674948 12551895 A further step of gel filtration in a Superdex 75 column was performed to separate the monomeric protein from aggregated material. - automatic transfer from 1o6y 2fum_3 PROBNOT 1 1 NPS NPS 16674948 12551895 A further step of gel filtration in a Superdex 75 column was performed to separate the monomeric protein from aggregated material. - automatic transfer from 1o6y 2fum_4 PROBNOT 1 1 NPS NPS 16674948 12551895 A further step of gel filtration in a Superdex 75 column was performed to separate the monomeric protein from aggregated material. - automatic transfer from 1o6y 2fus NO 4 4 D2 D2 9098893 9098893 Interface geometry conserved with 1q5n (22%) -- Annotation transfered from 1fur 2fvd NO 1 1 NPS NPS 17064073 11335721 Cdks do not in general form homo-oligomers - automatic transfer from 1gij 2fvj PROBYES 1 2 NPS C2 16373399 15258145 PISA says homodimer and identicals are homodimers - automatic transfer from 1wm0 2fvp PROBYES 2 1 C2 NPS 17003051 10669612 BU changed since last release and is now incorrect - - automatic transfer from 1qai 2fvq PROBYES 2 1 C2 NPS 17003051 10669612 BU changed since last release and is now incorrect - - automatic transfer from 1qai 2fvr PROBYES 2 1 C2 NPS 17003051 10669612 BU changed since last release and is now incorrect - - automatic transfer from 1qai 2fvs PROBYES 2 1 C2 NPS 17003051 10669612 BU changed since last release and is now incorrect - - automatic transfer from 1qai 2fvx PROBNOT 1 1 NPS NPS 9063874 9063874 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 2fdx 2fvy NA 1 2 NPS C2 17473016 0 Ecocyc says it forms dimers but I am not sure whether this may require some additional domain like a transmembrane helix? - automatic transfer from 1glg 2fw0 NA 1 2 NPS C2 17473016 0 Ecocyc says it forms dimers but I am not sure whether this may require some additional domain like a transmembrane helix? - automatic transfer from 1glg 2fw4_1 NO 1 1 NPS NPS 16870440 0 10529183 says monomer - automatic transfer from 1crm 2fw4_2 NO 1 1 NPS NPS 16870440 0 10529183 says monomer - automatic transfer from 1crm 2fwn NO 4 4 D2 D2 0 9665697 Interface geometry conserved with 1ovm (25%) - automatic transfer from 1bfd 2fww NO 4 4 D2 D2 16681368 9521329 The paper shows tha tit is a tetramer. In addition, it is would be active only as a tetramer - automatic transfer from 1a0l 2fwy NA 1 1 NPS NPS 16884307 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automatic transfer from 1uy6 2fwz NA 1 1 NPS NPS 16884307 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automatic transfer from 1uy6 2fx2 PROBNOT 1 1 NPS NPS 2002503 2002503 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1f4p 2fx3 PROBNOT 1 1 NPS NPS 16552145 9838020 BU changed since last release and is now corrected - EF-Tu from bacteria (from Escherichia coli, Ec, if not otherwise stated by subscripts: Thermus thermophilus, Tt, and T. aquaticus, Ta; Salmonella typhimurium, St) and its eukaryotic/archeal counterpart (EF-1α) is a monomeric protein with molecular weight of 40–52 kDa. - automaticaly inferred from 1dg1 2fx4 PROBNOT 1 1 NPS NPS 16681368 0 - automatic transfer from 1az8 2fx6 PROBNOT 1 1 NPS NPS 16681368 0 - automatic transfer from 1az8 2fxf NO 2 2 C2 C2 0 0 Same dimer as 2b3u -- Annotation transfered from 2f5i 2fxr NO 4 4 D2 D2 16681368 9521329 The paper shows tha tit is a tetramer. In addition, it is would be active only as a tetramer - automatic transfer from 1a0l 2fxu PROBNOT 1 1 NPS NPS 16551075 11932258 BU changed since last release and is now corrected - Actin does not form closed dimer - automaticaly inferred from 1lcu 2fym_1 NO 2 2 C2 C2 16516921 11676541 Interface conserved with 1one (50% id) -- Annotation transfered from 1e9i_1 2fym_2 NO 2 2 C2 C2 16516921 11676541 Interface conserved with 1one (50% id) -- Annotation transfered from 1e9i_1 2fyp NA 2 1 C2 NPS 0 12970348 BU changed since last release and is now incorrect - Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automaticaly inferred from 1qy5 2fys_1 PROBNOT 1 1 NPS NPS 16567630 9753691 - automatic transfer from 4erk 2fys_2 PROBNOT 1 1 NPS NPS 16567630 9753691 - automatic transfer from 4erk 2fz4 PROBNOT 1 1 NPS NPS 16600867 15060080 BU changed since last release and is now corrected - Paper says nothing, PISA says monomeric - automaticaly inferred from 1vkj 2fz8 NA 1 1 NPS NPS 16952371 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2fz9 NA 1 1 NPS NPS 16952371 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2fzb NA 1 1 NPS NPS 16952371 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2fzd NA 1 1 NPS NPS 16952371 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2fze NO 2 2 C2 C2 16605250 12196016 - automatic transfer from 1m6w 2fzh PROBNOT 1 1 NPS NPS 17019704 10194348 PISA also says monomer - Human is monomeric so I guess it should be - Only Thermogota seems to be dimeric - automatic transfer from 1cd2 2fzi PROBNOT 1 1 NPS NPS 17019704 10194348 PISA also says monomer - Human is monomeric so I guess it should be - Only Thermogota seems to be dimeric - automatic transfer from 1cd2 2fzl PROBNOT 1 1 NPS NPS 16600867 15060080 BU changed since last release and is now corrected - Paper says nothing, PISA says monomeric - automaticaly inferred from 1vkj 2fzw NO 2 2 C2 C2 16605250 12196016 - automatic transfer from 1m6w 2g0g PROBYES 2 2 NS C2 16640330 15258145 BU changed since last release and is now incorrect - PISA says homodimer and identicals are homodimers - automaticaly inferred from 1wm0 2g0h PROBYES 2 2 NS C2 16640330 15258145 BU changed since last release and is now incorrect - PISA says homodimer and identicals are homodimers - automaticaly inferred from 1wm0 2g0r NO 1 1 NPS NPS 16790933 0 Myoglobin is a monomeric protein (8663546) - automatic transfer from 1a6m 2g0s NO 1 1 NPS NPS 16790933 0 Myoglobin is a monomeric protein (8663546) - automatic transfer from 1a6m 2g0v PROBYES 2 1 NS NPS 16790933 0 BU changed since last release and is now incorrect - Myoglobin is a monomeric protein (8663546) - automaticaly inferred from 1a6m 2g0x PROBYES 2 1 NS NPS 16790933 0 BU changed since last release and is now incorrect - Myoglobin is a monomeric protein (8663546) - automaticaly inferred from 1a6m 2g0z PROBYES 2 1 NS NPS 16790933 0 BU changed since last release and is now incorrect - Myoglobin is a monomeric protein (8663546) - automaticaly inferred from 1a6m 2g10 PROBYES 2 1 NS NPS 16790933 0 BU changed since last release and is now incorrect - Myoglobin is a monomeric protein (8663546) - automaticaly inferred from 1a6m 2g11 PROBYES 2 1 NS NPS 16790933 0 BU changed since last release and is now incorrect - Myoglobin is a monomeric protein (8663546) - automaticaly inferred from 1a6m 2g12 PROBYES 2 1 NS NPS 16790933 0 BU changed since last release and is now incorrect - Myoglobin is a monomeric protein (8663546) - automaticaly inferred from 1a6m 2g14 PROBYES 2 1 NS NPS 16790933 0 BU changed since last release and is now incorrect - Myoglobin is a monomeric protein (8663546) - automaticaly inferred from 1a6m 2g1j_1 PROBNOT 1 1 NPS NPS 16834327 12054870 SP says monomer - automatic transfer from 1l4u 2g1j_2 PROBNOT 1 1 NPS NPS 16834327 12054870 SP says monomer - automatic transfer from 1l4u 2g1k PROBNOT 1 1 NPS NPS 16834327 12054870 SP says monomer - automatic transfer from 1l4u 2g1q_1 PROBNOT 1 1 NPS NPS 16603356 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2g1q_2 PROBNOT 1 1 NPS NPS 16603356 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2g3p YES 2 1 C2 NPS 10329170 10329170 However, we could find no evidence of dimer formation of D1D2-fd, as judged by gel-filtration chromatography or light-scattering at protein concentrations (10 mg/ml) close to those used in the crystallisation set-up. Dimer formation may therefore be an artifact of the high-salt crystallisation conditions and may not reflect an interaction of biological relevance. -- good interesting example of corrected error for the paper 2g3t_1 NO 2 2 C2 C2 0 0 Same dimer as 2b3u -- Annotation transfered from 2f5i 2g3t_2 NO 2 2 C2 C2 0 0 Same dimer as 2b3u -- Annotation transfered from 2f5i 2g4g NO 4 4 D2 D2 17196219 11106758 - automatic transfer from 1g1o 2g4h NO 24 24 Octa Octa 17327674 0 Interface geometry conserved with 1lb3 (80%) - automatic transfer from 1ies 2g4i PROBNOT 4 4 D2 D2 17327674 0 BU changed since last release and is now corrected - - automaticaly inferred from 1qgl 2g4j PROBNOT 4 4 D2 D2 17327674 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o1h 2g4l NO 2 2 C2 C2 17327674 14998991 PISA, SP, paper and I say homodimer - automatic transfer from 1sc9 2g4p NO 1 1 NPS NPS 17327674 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2g4q NO 1 1 NPS NPS 17327674 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2g4t PROBNOT 1 1 NPS NPS 17327674 9443341 - automatic transfer from 1c1m 2g4u PROBNOT 1 1 NPS NPS 17327674 9443341 - automatic transfer from 1c1m 2g4v PROBNOT 1 1 NPS NPS 17327674 0 - automatic transfer from 1p7v 2g4w_1 PROBNOT 1 1 NPS NPS 17327674 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 2g4w_2 PROBNOT 1 1 NPS NPS 17327674 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 2g4x PROBNOT 1 1 NPS NPS 17327674 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 2g4y PROBNOT 1 1 NPS NPS 17327674 10504569 BU changed since last release and is now corrected - Thaumatin is a stable monomeric protein of 22kDa - automaticaly inferred from 1thw 2g50_1 PROBNOT 4 4 D2 D2 16634623 8193145 BU changed since last release and is now corrected - 15299671 says tetramer - automaticaly inferred from 1pkn 2g50_2 PROBNOT 4 4 D2 D2 16634623 8193145 BU changed since last release and is now corrected - 15299671 says tetramer - automaticaly inferred from 1pkn 2g51 PROBNOT 1 1 NPS NPS 17327674 11134922 - automatic transfer from 1gdn 2g52 PROBNOT 1 1 NPS NPS 17327674 11134922 - automatic transfer from 1gdn 2g55 PROBNOT 1 1 NPS NPS 17327674 0 - automatic transfer from 1az8 2g58 PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2g5l NO 4 4 D2 D2 0 9148939 BU changed since last release and is now corrected - - automatic transfer from 1vwl 2g5n PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1az8 2g5p NO 2 2 C2 C2 16759095 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2g5r PROBNOT 1 1 NPS NPS 16623661 14747738 Paper doesnt mention a dimer and PISA says monomer - automatic transfer from 1nko 2g5t NO 2 2 C2 C2 16759095 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2g5u NO 4 4 D2 D2 15610856 11106758 - automatic transfer from 1g1o 2g5v PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1az8 2g63_1 NO 2 2 C2 C2 16759095 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2g63_2 NO 2 2 C2 C2 16759095 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2g6d PROBNOT 1 1 NPS NPS 0 12641451 SP says monomer - automatic transfer from 1nqc 2g6h NO 2 2 C2 C2 16804678 12437343 Clear dimer - automatic transfer from 1m00 2g6i NO 2 2 C2 C2 16804678 12437343 Clear dimer - automatic transfer from 1m00 2g6k NO 2 2 C2 C2 16804678 12437343 Clear dimer - automatic transfer from 1m00 2g6l NO 2 2 C2 C2 16804678 12437343 Clear dimer - automatic transfer from 1m00 2g6m NO 2 2 C2 C2 16804678 12437343 Clear dimer - automatic transfer from 1m00 2g6n NO 2 2 C2 C2 16804678 12437343 Clear dimer - automatic transfer from 1m00 2g6o NO 2 2 C2 C2 16804678 11331003 Clear dimer - automatic transfer from 1fol 2g6w PROBNOT 2 2 C2 C2 16557306 10642176 BU changed since last release and is now corrected - Paper describes a dimer and PISA finds it - automaticaly inferred from 1dje 2g73 PROBYES 2 1 C2 NPS 0 12540835 Seems to be a monomer - PISA would be wrong - automatic transfer from 1nfs 2g74 PROBYES 2 1 C2 NPS 0 12540835 Seems to be a monomer - PISA would be wrong - automatic transfer from 1nfs 2g7y_1 PROBNOT 1 1 NPS NPS 0 12641451 SP says monomer - automatic transfer from 1nqc 2g7y_2 PROBNOT 1 1 NPS NPS 0 12641451 SP says monomer - automatic transfer from 1nqc 2g83_1 PROBNOT 1 1 NPS NPS 16981699 7481799 Normally part of a heterotrimer, so apparently no homo-interaction. - automatic transfer from 1gdd 2g83_2 PROBNOT 1 1 NPS NPS 16981699 7481799 Normally part of a heterotrimer, so apparently no homo-interaction. - automatic transfer from 1gdd 2g8o PROBNOT 2 2 C2 C2 0 10648646 BU changed since last release and is now corrected - Clear dimer - automaticaly inferred from 1qqq 2g8q_1 PROBNOT 1 1 NPS NPS 16730994 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 2g8q_2 PROBNOT 1 1 NPS NPS 16730994 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 2g8r_1 PROBNOT 1 1 NPS NPS 16730994 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 2g8r_2 PROBNOT 1 1 NPS NPS 16730994 3680242 BU changed since last release and is now corrected - No domain swapping - Known as a monomer, SP and PISA say monomer - automaticaly inferred from 1rbb 2g8t PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1az8 2g98_1 PROBNOT 1 1 NPS NPS 10915766 3052280 y-Crystallins are exclusively monomeric - automatic transfer from 1h4a 2g98_2 PROBNOT 1 1 NPS NPS 10915766 3052280 y-Crystallins are exclusively monomeric - automatic transfer from 1h4a 2g9k NO 4 4 D2 D2 15610856 11106758 - automatic transfer from 1g1o 2g9q PROBYES 2 2 C2 C2 16970395 9384557 Wrong interface of the dimer - automatic transfer from 2amv 2g9r PROBYES 2 2 C2 C2 16970395 9384557 Wrong interface of the dimer - automatic transfer from 2amv 2g9u PROBYES 2 2 C2 C2 16970395 9384557 Wrong interface of the dimer - automatic transfer from 2amv 2g9v PROBYES 2 2 C2 C2 16970395 9384557 Wrong interface of the dimer - automatic transfer from 2amv 2ga2 PROBNOT 1 1 NPS NPS 0 9812898 Paper says nothing, PISA says monomer - automatic transfer from 1b6a 2gab NO 4 4 D2 D2 15610856 11106758 - automatic transfer from 1g1o 2gal YES 2 1 C2 NPS 9760227 9760227 Paper says: The hGal-7 molecule crystallizes as a dimer, although in solution it is known to exist as a monomer unlike most other mammalian galectins, except Gal-10 (6). -- Annotation transfered from 5gal 2gar PROBNOT 1 1 NPS NPS 9698564 9698564 Paper says: E. coli GarTfase exhibits a pH-dependent monomer-dimer equilibrium with the monomer preferably populated above pH 7.4 and the dimer below pH 6.6 -- BUT this one contains a mutation at the interface that prevent dimer formation even at low pH. -- check 12450384 for good summary of the protein 2gbp NA 1 2 NPS C2 3057628 3057628 Ecocyc says it forms dimers but I am not sure whether this may require some additional domain like a transmembrane helix? -- Annotation transfered from 1glg 2gc8_1 PROBNOT 1 1 NPS NPS 16722622 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2gc8_2 PROBNOT 1 1 NPS NPS 16722622 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2gch NA 4 1 C2 NPS 6914398 6914398 BU changed since last release and is now incorrect - They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 2gct NA 2 1 C2 NPS 1888717 1888717 They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 2gd1 NO 4 4 D2 D2 3210237 3210237 SP says homotetramer - papers too -- Annotation transfered from 1npt 2gd8 PROBNOT 1 1 NPS NPS 17181151 8987974 9000633 says monomeric - automatic transfer from 1uga 2gdd NO 4 4 D2 D2 0 9521329 The paper shows tha tit is a tetramer. In addition, it is would be active only as a tetramer - automatic transfer from 1a0l 2gdm PROBNOT 1 1 NPS NPS 7643380 7643380 SP says monomer 2gdo PROBNOT 1 1 NPS NPS 16603354 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2gds NO 4 4 D2 D2 10488113 1394426 Paper says tetramer - automatic transfer from 1n0j 2gdu NO 2 2 C2 C2 16990265 14756551 Paper says: Native molecular weight determination indicated that BiSP is a homodimer in solution, estimated by gel filtration experiments at pH 6.5. To verify the dimer formation at crystallization pH, dynamic light scattering was performed. Results confirmed dimer formation at crystallization pH 8.5 and at pH 6.5 (data not shown) - automatic transfer from 1r7a 2gdv NO 2 2 C2 C2 0 14756551 Paper says: Native molecular weight determination indicated that BiSP is a homodimer in solution, estimated by gel filtration experiments at pH 6.5. To verify the dimer formation at crystallization pH, dynamic light scattering was performed. Results confirmed dimer formation at crystallization pH 8.5 and at pH 6.5 (data not shown) - automatic transfer from 1r7a 2geh PROBNOT 1 1 NPS NPS 16759856 8987974 9000633 says monomeric - automatic transfer from 1uga 2gfc NO 1 1 NPS NPS 16699172 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 2gfd NA 2 1 C2 NPS 0 12970348 BU changed since last release and is now incorrect - Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automaticaly inferred from 1qy5 2gfj_1 YES 1 4 NPS D2 0 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automatic transfer from 1sml 2gfj_2 YES 1 4 NPS D2 0 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automatic transfer from 1sml 2gfk_1 YES 1 4 NPS D2 0 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automatic transfer from 1sml 2gfk_2 YES 1 4 NPS D2 0 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automatic transfer from 1sml 2gfs PROBNOT 1 1 NPS NPS 16509574 11896401 - automatic transfer from 1kv1 2gh7 NO 4 4 D2 D2 16699183 9148939 BU changed since last release and is now corrected - - automatic transfer from 1vwl 2ghg PROBNOT 1 1 NPS NPS 16644221 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2ghy NO 2 2 C2 C2 16699189 0 BU changed since last release and is now corrected - - automatic transfer from 1gmg_2 2giu PROBNOT 2 2 C2 C2 16632357 0 - automatic transfer from 1qkm 2gj4 PROBYES 2 2 C2 C2 16945526 9384557 Wrong interface of the dimer - automatic transfer from 2amv 2gkr NA 1 2 NPS NS 17266986 1870129 BU changed since last release and is now incorrect - - automaticaly inferred from 4ovo 2glk PROBNOT 4 4 D2 D2 16707576 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o1h 2glr NO 2 2 C2 C2 8145243 8145243 -- Annotation transfered from 1bay 2gls NO 12 12 D6 D6 2572586 2572586 Salmonella typhimurium GS has a molecular mass of 620 kDa and is a dodecamer with 622 symmetry -- Annotation transfered from 1f1h 2glt PROBNOT 4 4 D2 D2 9010922 9010922 SP says homotetramer 2gm1_1 PROBNOT 1 1 NPS NPS 16730979 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2gm1_2 PROBNOT 1 1 NPS NPS 16730979 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2gm1_3 PROBNOT 1 1 NPS NPS 16730979 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2gm1_4 PROBNOT 1 1 NPS NPS 16730979 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2gm9 PROBYES 2 2 C2 C2 16945526 9384557 Wrong interface of the dimer - automatic transfer from 2amv 2gme NO 2 2 C2 C2 16824540 12595543 Implied in paper that it is a dimer, PISA also says that - automatic transfer from 1n3q 2gmm NO 2 2 C2 C2 16824540 12595543 Implied in paper that it is a dimer, PISA also says that - automatic transfer from 1n3q 2gmp NO 2 2 C2 C2 16824540 12595543 Implied in paper that it is a dimer, PISA also says that - automatic transfer from 1n3q 2gmt NA 2 1 C2 NPS 7947790 7947790 They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 2gn3 NO 2 2 C2 C2 16824540 12595543 Implied in paper that it is a dimer, PISA also says that - automatic transfer from 1n3q 2gn7 NO 2 2 C2 C2 16824540 12595543 Implied in paper that it is a dimer, PISA also says that - automatic transfer from 1n3q 2gnb NO 2 2 C2 C2 16824540 12595543 Implied in paper that it is a dimer, PISA also says that - automatic transfer from 1n3q 2gnd NO 2 2 C2 C2 16824540 12595543 Implied in paper that it is a dimer, PISA also says that - automatic transfer from 1n3q 2gnk YES 3 3 NS C3 9733647 9733647 Paper says: The trimers formed by native GlnK (Figure 2) and the GlnK/ATP complex are basically the same. 2gnm NO 2 2 C2 C2 16824540 12595543 Implied in paper that it is a dimer, PISA also says that - automatic transfer from 1n3q 2gns PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2gnt NO 2 2 C2 C2 16824540 12595543 Implied in paper that it is a dimer, PISA also says that - automatic transfer from 1n3q 2gp7_1 NO 2 2 C2 C2 16990259 11864604 Paper says dimer - automatic transfer from 1kv6 2gp7_2 NO 2 2 C2 C2 16990259 11864604 Paper says dimer - automatic transfer from 1kv6 2gpa NO 2 2 C2 C2 10548038 10548038 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 2gpb NO 2 2 C2 C2 2125493 2125493 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 2gpn NO 2 2 C2 C2 9568898 9568898 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 2gpo NO 2 2 C2 C2 16990259 11864604 Paper says dimer - automatic transfer from 1kv6 2gpp NO 2 2 C2 C2 16990259 11864604 Paper says dimer - automatic transfer from 1kv6 2gpr PROBNOT 1 1 NPS NPS 9705652 9705652 Paper says nothing, crystal packing different from 1gpr - PISA says monomer 2gpu NO 2 2 C2 C2 16990259 11864604 Paper says dimer - automatic transfer from 1kv6 2gqn PROBNOT 4 4 D2 D2 17300162 8831789 - automatic transfer from 1cl1 2gqp_1 NA 1 1 NPS NPS 0 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 2gqp_2 NA 1 1 NPS NPS 0 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 2grt NO 2 2 C2 C2 9174360 9174360 Paper says dimer -- Annotation transfered from 5grt 2gs2 NA 2 1 NS NPS 16777603 12196540 BU changed since last release and is now incorrect - The present data do not permit us to conclude that these contacts also arise in a cellular context - paper says that the protein may form dimers or even oligomers but they are not sure about these contacts - automaticaly inferred from 1m17 2gs6 NA 2 1 NS NPS 16777603 12196540 BU changed since last release and is now incorrect - The present data do not permit us to conclude that these contacts also arise in a cellular context - paper says that the protein may form dimers or even oligomers but they are not sure about these contacts - automaticaly inferred from 1m17 2gsa NO 2 2 C2 C2 9144156 9144156 Paper says dimer 2gsq NO 2 2 C2 C2 8710848 8710848 2gsr NO 2 2 C2 C2 7932743 7932743 2gss NO 2 2 C2 C2 9012673 9012673 -- Annotation transfered from 9gss 2gst NO 2 2 C2 C2 8110735 8110735 -- Annotation transfered from 6gsv 2gtk PROBYES 1 2 NPS C2 16737814 15258145 PISA says homodimer and identicals are homodimers - automatic transfer from 1wm0 2gtm PROBNOT 1 1 NPS NPS 16750367 11896401 - automatic transfer from 1kv1 2gtn PROBNOT 1 1 NPS NPS 16750367 11896401 - automatic transfer from 1kv1 2gtu NO 2 2 C2 C2 10652317 0 -- Annotation transfered from 1hna 2gub PROBNOT 4 4 D2 D2 16707576 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o1h 2guy PROBNOT 1 1 NPS NPS 16880540 1930835 SP says monomer - automatic transfer from 6taa 2gv2 PROBNOT 1 1 NPS NPS 16925398 8875929 cf. 1rv1 - automatic transfer from 1ycr 2gv6 PROBNOT 1 1 NPS NPS 16821772 11696548 Paper says nothing - related are monomers and PISA says monomer - automatic transfer from 1eax 2gv7 PROBNOT 1 1 NPS NPS 16821772 11696548 Paper says nothing - related are monomers and PISA says monomer - automatic transfer from 1eax 2gvy_1 PROBNOT 1 1 NPS NPS 16880540 1930835 SP says monomer - automatic transfer from 6taa 2gvy_2 PROBNOT 1 1 NPS NPS 16880540 1930835 SP says monomer - automatic transfer from 6taa 2gwj PROBNOT 1 1 NPS NPS 16905096 11932258 BU changed since last release and is now corrected - Actin does not form closed dimer - automaticaly inferred from 1lcu 2gwk YES 2 1 C2 NPS 16905096 11932258 Actin does not form closed dimer - automatic transfer from 1lcu 2gwx_1 YES 1 2 NPS C2 10198642 10198642 BU changed since last release and is now incorrect - Either dimer or monomer but not not symmetrical dimer - automaticaly inferred from 3gwx 2gwx_2 YES 1 2 NPS C2 10198642 10198642 BU changed since last release and is now incorrect - Either dimer or monomer but not not symmetrical dimer - automaticaly inferred from 3gwx 2gyd NO 24 24 Octa Octa 17163775 0 Interface geometry conserved with 1lb3 (80%) - automatic transfer from 1ies 2gyi NO 4 4 D2 D2 7893671 7893671 -- Annotation transfered from 1s5m 2gyo PROBNOT 2 2 C2 C2 17524982 12502353 BU changed since last release and is now corrected - - automaticaly inferred from 1mzs 2h15 PROBNOT 1 1 NPS NPS 17125255 8987974 9000633 says monomeric - automatic transfer from 1uga 2h1u PROBNOT 1 1 NPS NPS 16754679 9443341 - automatic transfer from 1c1m 2h40 PROBNOT 1 1 NPS NPS 16735511 12955149 BU changed since last release and is now corrected - No info about oligomer in all papers, PISa says monomer and inspection of the structure let think it is right. - automaticaly inferred from 1udu 2h42_1 PROBNOT 1 1 NPS NPS 16735511 12955149 BU changed since last release and is now corrected - No info about oligomer in all papers, PISa says monomer and inspection of the structure let think it is right. - automaticaly inferred from 1udu 2h42_2 PROBNOT 1 1 NPS NPS 16735511 12955149 BU changed since last release and is now corrected - No info about oligomer in all papers, PISa says monomer and inspection of the structure let think it is right. - automaticaly inferred from 1udu 2h42_3 PROBNOT 1 1 NPS NPS 16735511 12955149 BU changed since last release and is now corrected - No info about oligomer in all papers, PISa says monomer and inspection of the structure let think it is right. - automaticaly inferred from 1udu 2h44 PROBNOT 1 1 NPS NPS 16735511 12955149 BU changed since last release and is now corrected - No info about oligomer in all papers, PISa says monomer and inspection of the structure let think it is right. - automaticaly inferred from 1udu 2h4e PROBNOT 4 4 D2 D2 17175208 9789022 BU changed since last release and is now corrected - All dimers similar to that one are found to be tetramers by PISA. Because the native structure is tetrameric, dimer are certainly mistakes - automaticaly inferred from 1bmz 2h4g PROBNOT 1 1 NPS NPS 16806920 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2h4k PROBNOT 1 1 NPS NPS 16806920 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2h4n PROBNOT 1 1 NPS NPS 9398308 9398308 9000633 says monomeric -- Annotation transfered from 1uga 2h4x NO 2 2 C2 C2 0 15258155 11038361 and SP say dimer - automatic transfer from 1t8p 2h4z NO 2 2 C2 C2 0 15258155 11038361 and SP say dimer - automatic transfer from 1t8p 2h52 NO 2 2 C2 C2 0 15258155 11038361 and SP say dimer - automatic transfer from 1t8p 2h55 NA 1 1 NPS NPS 16884307 0 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automatic transfer from 1uy6 2h5c NO 1 1 NPS NPS 16834383 2611204 9846867 says monomer - automatic transfer from 1p05 2h5d NO 1 1 NPS NPS 16834383 2611204 9846867 says monomer - automatic transfer from 1p05 2h5l_1 NO 4 4 D2 D2 17214973 10387078 SP says tetramer, interface geometry conserved among rat and human. - automatic transfer from 1b3r 2h5l_2 NO 4 4 D2 D2 17214973 10387078 SP says tetramer, interface geometry conserved among rat and human. - automatic transfer from 1b3r 2h5s PROBNOT 1 1 NPS NPS 17017804 14609325 - automatic transfer from 1ong 2h6a_1 YES 1 4 NPS D2 0 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automatic transfer from 1sml 2h6a_2 YES 1 4 NPS D2 0 9811546 Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automatic transfer from 1sml 2h6w PROBNOT 1 1 NPS NPS 16781732 9808622 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - Others are monomers, paper says nothing and PISA says monomer. - automaticaly inferred from 1bsx 2h6x_1 NO 1 1 NPS NPS 0 10489448 Paper says: Gel-filtration chromatography and polyacrylamide gel electrophoresis suggest that CVWC Trx may exist as both monomers and dimers in solution. In contrast, analytical ultracentrifugation of the CVWC enzyme revealed no significant dimer formation in solution at concentrations up to 30 µM (data not shown). - likely monomer-dimer equilibrium - automatic transfer from 1txx 2h6x_2 NO 1 1 NPS NPS 0 10489448 Paper says: Gel-filtration chromatography and polyacrylamide gel electrophoresis suggest that CVWC Trx may exist as both monomers and dimers in solution. In contrast, analytical ultracentrifugation of the CVWC enzyme revealed no significant dimer formation in solution at concentrations up to 30 µM (data not shown). - likely monomer-dimer equilibrium - automatic transfer from 1txx 2h7c NO 6 6 D3 D3 16962139 12725862 exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automatic transfer from 1mx1 2h7i YES 1 4 NPS D2 17034137 7886450 BU changed since last release and is now incorrect - - automaticaly inferred from 1eny 2h7j_1 PROBNOT 1 1 NPS NPS 17034136 12641451 SP says monomer - automatic transfer from 1nqc 2h7j_2 PROBNOT 1 1 NPS NPS 17034136 12641451 SP says monomer - automatic transfer from 1nqc 2h7l YES 1 4 NPS D2 17034137 7886450 BU changed since last release and is now incorrect - - automaticaly inferred from 1eny 2h7m YES 1 4 NPS D2 17034137 7886450 BU changed since last release and is now incorrect - - automaticaly inferred from 1eny 2h7n YES 1 4 NPS D2 17034137 7886450 BU changed since last release and is now incorrect - - automaticaly inferred from 1eny 2h7p YES 1 4 NPS D2 17034137 7886450 BU changed since last release and is now incorrect - - automaticaly inferred from 1eny 2h7q PROBNOT 1 1 NPS NPS 16943206 0 BU changed since last release and is now corrected - - automaticaly inferred from 1o76 2h8m_1 NA 1 1 NPS NPS 0 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 2h8m_2 NA 1 1 NPS NPS 0 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 2h9i PROBNOT 4 4 D2 D2 17227913 7886450 BU changed since last release and is now corrected - - automaticaly inferred from 1eny 2h9j NO 1 1 NPS NPS 17120266 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2h9k NO 1 1 NPS NPS 17120266 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2had NO 1 1 NPS NPS 2026135 2026135 SP says monomer -- Annotation transfered from 1edb 2ham PROBNOT 1 1 NPS NPS 16913708 11344298 paper says nothing, PISA says monomer - automatic transfer from 1ie9 2hap PROBNOT 2 2 NS NS 9886287 9886294 Paper says: The structure reveals that HAP1 is bound in a dramatically asymmetric manner to the DNA target. - automatic transfer from 1hwt_1 2har PROBNOT 1 1 NPS NPS 16913708 11344298 paper says nothing, PISA says monomer - automatic transfer from 1ie9 2has PROBNOT 1 1 NPS NPS 16913708 11344298 paper says nothing, PISA says monomer - automatic transfer from 1ie9 2hax YES 2 1 C2 NPS 17266726 11800562 BU changed since last release and is now incorrect - Paper says monomeric based on 9501917 - automaticaly inferred from 1hzb 2hb1 PROBNOT 1 1 NPS NPS 16806920 15817824 Apparently it can also exist in a dimeric form - automatic transfer from 1i57 2hb7 PROBNOT 1 1 NPS NPS 16913708 11344298 paper says nothing, PISA says monomer - automatic transfer from 1ie9 2hb8 PROBNOT 1 1 NPS NPS 16913708 11344298 paper says nothing, PISA says monomer - automatic transfer from 1ie9 2hb9 PROBNOT 4 4 D2 D2 0 9811546 BU changed since last release and is now corrected - Paper says: L1 is unique amongst all known beta-lactamases in that it exists as a tetramer. - automaticaly inferred from 1sml 2hbc PROBYES 2 4 C2 D2 -1 0 I am not sure how to fill in this form. Should I be filling in the details of what I think the structure should be? (reply:yes!) Although there is no specific evidence, this dimeric haemoglobin (a) structure forms a reasonable, haemoglobin-like tetramer after 2 fold symmetry is applied. This is a case where I think evidence to the contrary of a tetramer would be needed over evidence of a tetramer (on the grounds of homology). What does propagate changes mean in this context? I assume by homology , but that seems risky as other comments about special cases of homologues may exist. I would suggest that the form should come with a table of homologuues that I can explicitly pick (or pick all) to be annotated with this comment. Specifically I guess the comment applies all dimers that are 100% identical to this one? It would be nice to be able to automatically cross check with other sources. Will you provide the structure of the dimer? That is really critical I think. (reply: this is on the TO-DO list :) All the best, and sorry for the long comment , (reply: thank you!) Dan. For the historical record, this is the first structure annotated by a user :D 2hbg PROBNOT 1 1 NPS NPS 2585515 2585515 SP says monomer 2hch_1 NA 1 1 NPS NPS 0 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 2hch_2 NA 1 1 NPS NPS 0 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 2hck PROBYES 2 1 C2 NPS 9024658 9024658 Not found info about the dimer, interestingly it dimerizes at the level of the activation segment ... maybe, like in the case of the PLA, it is an inhibitory mechanism? - interesting - the author of the structure (Frank Sicheri) said that there is no biological relevance that he knows of 2hd4 PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1p7v 2hd6 PROBNOT 1 1 NPS NPS 16942027 8987974 9000633 says monomeric - automatic transfer from 1uga 2hdj_1 PROBNOT 1 1 NPS NPS 17034817 12899831 Swissprot and PISA say it is a monomer - automatic transfer from 1mrq 2hdj_2 PROBNOT 1 1 NPS NPS 17034817 12899831 Swissprot and PISA say it is a monomer - automatic transfer from 1mrq 2hdq_1 PROBNOT 1 1 NPS NPS 17072304 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 2hdq_2 PROBNOT 1 1 NPS NPS 17072304 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 2hdr_1 PROBNOT 1 1 NPS NPS 17072304 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 2hdr_2 PROBNOT 1 1 NPS NPS 17072304 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 2hds_1 PROBNOT 1 1 NPS NPS 17072304 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 2hds_2 PROBNOT 1 1 NPS NPS 17072304 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 2hdu_1 PROBNOT 1 1 NPS NPS 17072304 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 2hdu_2 PROBNOT 1 1 NPS NPS 17072304 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 2hea NO 1 1 NPS NPS 9398521 9398521 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2heb NO 1 1 NPS NPS 9398521 9398521 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2hec NO 1 1 NPS NPS 9398521 9398521 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2hed NO 1 1 NPS NPS 9398521 9398521 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2hee NO 1 1 NPS NPS 9398521 9398521 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2hef NO 1 1 NPS NPS 9398521 9398521 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2het_1 PROBNOT 1 1 NPS NPS 17015448 1358206 The elution volume of recoverin corresponds to a monomer. - automatic transfer from 1omr 2het_2 PROBNOT 1 1 NPS NPS 17015448 1358206 The elution volume of recoverin corresponds to a monomer. - automatic transfer from 1omr 2het_3 PROBNOT 1 1 NPS NPS 17015448 1358206 The elution volume of recoverin corresponds to a monomer. - automatic transfer from 1omr 2het_4 PROBNOT 1 1 NPS NPS 17015448 1358206 The elution volume of recoverin corresponds to a monomer. - automatic transfer from 1omr 2hex YES 5 10 C5 D5 10089443 10731422 BU changed since last release and is now incorrect - Paper says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium -- A decamer this protein may be, but the structure of this decamer it is not. Look at 1bhc and tell me that this structure is correct! - automaticaly inferred from 1b0c 2hfp PROBYES 1 2 NPS C2 16919947 9744270 BU changed since last release and is now incorrect - Paper says homodimer - automaticaly inferred from 1prg 2hg1_1 NA 1 1 NPS NPS 0 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 2hg1_2 NA 1 1 NPS NPS 0 12970348 Normally homodimer but there may be a problem with the C-terminal dimerization domain? - automatic transfer from 1qy5 2hh5_1 PROBNOT 1 1 NPS NPS 16876402 12641451 SP says monomer - automatic transfer from 1nqc 2hh5_2 PROBNOT 1 1 NPS NPS 16876402 12641451 SP says monomer - automatic transfer from 1nqc 2hha NO 2 2 C2 C2 16919457 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2hhf NO 2 2 C2 C2 17050531 12269802 Paper says dimer: The mammalian BCATs are homodimers with molecular masses ranging from about 41000 to 46000. - SP too - automatic transfer from 1kta 2hhj NO 2 2 C2 C2 0 15258155 11038361 and SP say dimer - automatic transfer from 1t8p 2hhm NO 2 2 C2 C2 1332026 8068620 - automatic transfer from 1imb 2hhn_1 PROBNOT 1 1 NPS NPS 16876402 12641451 SP says monomer - automatic transfer from 1nqc 2hhn_2 PROBNOT 1 1 NPS NPS 16876402 12641451 SP says monomer - automatic transfer from 1nqc 2hij_2 PROBYES 1 2 NPS C2 0 15342247 BU changed since last release and is now incorrect - 9914261 says: An accompanying consequence of the metastable state of the active serpins is a vulnerability to pathological intermolecular linkages as dimers, oligomers and polymers. -- disease associated to oligomerization - automaticaly inferred from 1jvq 2hip PROBYES 2 1 NS NPS 1917989 1917989 This is certainly an error - still the native state could be a dimer (see 1hpi, an email was sent to enquire) 2his PROBNOT 1 1 NPS NPS 9731776 9731776 Apparently the family doesnt form dimers but there is no clear evidence. -- Annotation transfered from 1exp 2hkk PROBNOT 1 1 NPS NPS 17127057 8987974 9000633 says monomeric - automatic transfer from 1uga 2hl4 PROBNOT 1 1 NPS NPS 17251017 8987974 9000633 says monomeric - automatic transfer from 1uga 2hlb PROBNOT 1 1 NPS NPS 17264214 7481799 Normally part of a heterotrimer, so apparently no homo-interaction. - automatic transfer from 1gdd 2hlc PROBYES 4 1 C2 NPS 15299709 15299709 Paper says: The collagenase purified from H. lineatum larvae is a monomeric enzyme of molecular weight 25 223 Da - Although tetrameric collagenases exist in other organisms - potentialy interessting 2hlp NO 4 4 D2 D2 10653643 10653643 Paper says tetramer 2hmb PROBNOT 1 1 NPS NPS 1526991 1526991 No info found but PISA says monomer and homologous proteins are monomeric so I will assume it is one. -- Annotation transfered from 1hmr 2hmp YES 2 1 C2 NPS 16893553 11932258 Actin does not form closed dimer - automatic transfer from 1lcu 2hnc PROBNOT 1 1 NPS NPS 17000110 8987974 9000633 says monomeric - automatic transfer from 1uga 2hnp PROBNOT 1 1 NPS NPS 8128219 8128219 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 2hnq PROBNOT 1 1 NPS NPS 8128219 8128219 Apparently it can also exist in a dimeric form -- Annotation transfered from 1i57 2hnx PROBNOT 1 1 NPS NPS 17077479 15357970 PAper says nothing, PISA says monomer - automatic transfer from 1tou 2hoc PROBNOT 1 1 NPS NPS 17000110 8987974 9000633 says monomeric - automatic transfer from 1uga 2hog PROBNOT 1 1 NPS NPS 16978863 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2hpd_1 NA 1 1 NPS NPS 8342039 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 2hpd_2 NA 1 1 NPS NPS 8342039 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 2hpe NO 2 2 C2 C2 0 7613867 - automatic transfer from 1hii 2hpf NO 2 2 C2 C2 0 7613867 - automatic transfer from 1hii 2hph NA 1 2 NPS C2 0 0 Ecocyc says it forms dimers but I am not sure whether this may require some additional domain like a transmembrane helix? - automatic transfer from 1glg 2hpr PROBNOT 1 1 NPS NPS 7704530 9334229 E. coli HPr is a small, monomeric protein (I assume it is similar for subtilis) 2hpz PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1p7v 2hr5 NO 2 2 C2 C2 0 15468318 Swapped dimer - automatic transfer from 1nnq 2hrl PROBNOT 1 1 NPS NPS 16895906 14747738 Paper doesnt mention a dimer and PISA says monomer - automatic transfer from 1nko 2hrq_1 PROBYES 3 6 C3 D3 17407327 12725862 BU changed since last release and is now incorrect - exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automaticaly inferred from 1mx1 2hrq_2 PROBYES 3 6 C3 D3 17407327 12725862 BU changed since last release and is now incorrect - exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automaticaly inferred from 1mx1 2hrr PROBYES 3 6 C3 D3 17407327 12725862 BU changed since last release and is now incorrect - exists in a trimer-hexamer equilibrium that can be shifted toward trimer through the binding of compounds to a site on the surface of the enzyme. - automaticaly inferred from 1mx1 2hsd NO 4 4 D2 D2 7922040 7922040 SP says homotetramer -- Annotation transfered from 1hdc 2hsh PROBYES 1 2 NPS C2 17260951 9369469 BU changed since last release and is now incorrect - SP says dimer, paper too, interface geometry conserved with 1nsw (36%) - monomer dimer equilibrium -- very interesting paper: quantification of the interface strengh according to the pH (> 10 fold difference). - automaticaly inferred from 1aiu 2htn PROBNOT 24 24 Octa Octa 17077480 7664064 BU changed since last release and is now corrected - SP says 24-mer -- Symmetry problem? check - automatic transfer from 1bcf 2hts PROBNOT 1 1 NPS NPS 8284672 8284672 The protein is made of a DNA BD and a trimerization domain. Since the trimerization is not part of the structure I guess it should be a monomer -- Annotation transfered from 1fyk 2htx NO 1 1 NPS NPS 17461426 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2hu1 NO 1 1 NPS NPS 17461426 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2hv5 NA 1 1 NPS NPS 16952371 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2hvd NO 6 6 D3 D3 16944299 12972261 Hexamer of two different chains: A and B (A6, A5B, A4B2, A3B3, A2B4, AB5, B6). - Interesting for Dmitry - automatic transfer from 1ucn 2hvm PROBNOT 1 1 NPS NPS 8831791 8831791 -- Annotation transfered from 1kr1 2hvn NA 1 1 NPS NPS 16952371 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2hvo NA 1 1 NPS NPS 16952371 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2hvp NO 2 2 C2 C2 2645523 2645523 -- Annotation transfered from 1ajx 2hvx PROBNOT 1 1 NPS NPS 17361995 12614156 Paper says nothing, PISA says monomer - automatic transfer from 1nn6 2hwh_1 PROBNOT 1 1 NPS NPS 16934455 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2hwh_2 PROBNOT 1 1 NPS NPS 16934455 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2hwi_1 PROBNOT 1 1 NPS NPS 16934455 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2hwi_2 PROBNOT 1 1 NPS NPS 16934455 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2hx2 NO 2 2 C2 C2 17425297 11331003 Clear dimer - automatic transfer from 1fol 2hx3 NO 2 2 C2 C2 17425297 12437343 Clear dimer - automatic transfer from 1m00 2hx4 NO 2 2 C2 C2 17425297 12437343 Clear dimer - automatic transfer from 1m00 2hxk_1 PROBYES 1 2 NPS C2 17260951 9369469 BU changed since last release and is now incorrect - SP says dimer, paper too, interface geometry conserved with 1nsw (36%) - monomer dimer equilibrium -- very interesting paper: quantification of the interface strengh according to the pH (> 10 fold difference). - automaticaly inferred from 1aiu 2hxk_2 PROBYES 1 2 NPS C2 17260951 9369469 BU changed since last release and is now incorrect - SP says dimer, paper too, interface geometry conserved with 1nsw (36%) - monomer dimer equilibrium -- very interesting paper: quantification of the interface strengh according to the pH (> 10 fold difference). - automaticaly inferred from 1aiu 2hxk_3 PROBYES 1 2 NPS C2 17260951 9369469 BU changed since last release and is now incorrect - SP says dimer, paper too, interface geometry conserved with 1nsw (36%) - monomer dimer equilibrium -- very interesting paper: quantification of the interface strengh according to the pH (> 10 fold difference). - automaticaly inferred from 1aiu 2hxl PROBNOT 1 1 NPS NPS 16990002 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2hxq PROBNOT 1 1 NPS NPS 16990002 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2hxz_1 PROBNOT 1 1 NPS NPS 17034136 12641451 SP says monomer - automatic transfer from 1nqc 2hxz_2 PROBNOT 1 1 NPS NPS 17034136 12641451 SP says monomer - automatic transfer from 1nqc 2hxz_3 PROBNOT 1 1 NPS NPS 17034136 12641451 SP says monomer - automatic transfer from 1nqc 2hy0 PROBNOT 1 1 NPS NPS 16990002 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2hyf_1 NO 2 2 C2 C2 17118401 12847518 Interface geometry conserved down to 30% with 1b1b - automatic transfer from 1on1 2hyf_2 NO 2 2 C2 C2 17118401 12847518 Interface geometry conserved down to 30% with 1b1b - automatic transfer from 1on1 2hyg NO 2 2 C2 C2 17118401 12847518 Interface geometry conserved down to 30% with 1b1b - automatic transfer from 1on1 2i03_1 NO 2 2 C2 C2 17034148 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2i03_2 NO 2 2 C2 C2 17034148 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2i0g PROBNOT 2 2 C2 C2 17034120 0 - automatic transfer from 1qkm 2i0h PROBNOT 1 1 NPS NPS 16945533 11896401 - automatic transfer from 1kv1 2i0i_1 PROBNOT 1 1 NPS NPS 17267502 8757139 BU changed since last release and is now corrected - This is just a domain of a large protein. 15504326 says: Single-particle electron microscopy (EM) combined with biochemical measurements revealed the molecular shape of SAP97 and a monomer-dimer transition that depended on the N-terminal L27 domain. - automaticaly inferred from 1pdr 2i0i_2 PROBNOT 1 1 NPS NPS 17267502 8757139 BU changed since last release and is now corrected - This is just a domain of a large protein. 15504326 says: Single-particle electron microscopy (EM) combined with biochemical measurements revealed the molecular shape of SAP97 and a monomer-dimer transition that depended on the N-terminal L27 domain. - automaticaly inferred from 1pdr 2i0i_3 PROBNOT 1 1 NPS NPS 17267502 8757139 BU changed since last release and is now corrected - This is just a domain of a large protein. 15504326 says: Single-particle electron microscopy (EM) combined with biochemical measurements revealed the molecular shape of SAP97 and a monomer-dimer transition that depended on the N-terminal L27 domain. - automaticaly inferred from 1pdr 2i16 NA 1 1 NPS NPS 17139089 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2i17 NA 1 1 NPS NPS 17139089 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2i1b PROBNOT 1 1 NPS NPS 2602367 2602367 SP says monomer -- Annotation transfered from 21bi 2i1l_1 PROBNOT 1 1 NPS NPS 0 12910462 BU changed since last release and is now corrected - Enzyme, no reason for that type of interaction, plus this is a thermophile. - automaticaly inferred from 1mrz 2i1l_2 PROBNOT 1 1 NPS NPS 0 12910462 BU changed since last release and is now corrected - Enzyme, no reason for that type of interaction, plus this is a thermophile. - automaticaly inferred from 1mrz 2i1r_1 PROBNOT 1 1 NPS NPS 17049849 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2i1r_2 PROBNOT 1 1 NPS NPS 17049849 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2i42 PROBNOT 1 1 NPS NPS 0 8052312 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1ypt 2i4j NO 2 2 C2 C2 17403688 9744270 Paper says homodimer - automatic transfer from 1prg 2i4p NO 2 2 C2 C2 17403688 9744270 Paper says homodimer - automatic transfer from 1prg 2i4z NO 2 2 C2 C2 17403688 9744270 Paper says homodimer - automatic transfer from 1prg 2i5s PROBNOT 1 1 NPS NPS 0 8120892 - automatic transfer from 1onc 2i6z NO 1 1 NPS NPS 17180231 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2ica PROBNOT 1 1 NPS NPS 17125246 7479767 BU changed since last release and is now corrected - Interface very small - probably monomer - automaticaly inferred from 1lfa 2id4_1 NA 1 1 NPS NPS 17426142 17426142 Papers do not give information and PISA suggests a dimer. -- Annotation transfered from 2id4_2 2id4_2 NA 1 1 NPS NPS 17426142 17426142 Papers do not give information and PISA suggests a dimer. 2id8 PROBNOT 1 1 NPS NPS 17139083 0 - automatic transfer from 1p7v 2idj PROBNOT 4 4 D2 D2 17158459 10756111 BU changed since last release and is now corrected - Paper says tetramer - automaticaly inferred from 1d2g 2idk PROBNOT 4 4 D2 D2 17158459 10756111 BU changed since last release and is now corrected - Paper says tetramer - automaticaly inferred from 1d2g 2ie6 PROBYES 3 1 C3 NPS 17028130 12401794 BU changed since last release and is now incorrect - SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) - automaticaly inferred from 1n42 2ie7 PROBYES 3 1 C3 NPS 17028130 12401794 BU changed since last release and is now incorrect - SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) - automaticaly inferred from 1n42 2ieg PROBYES 2 2 C2 C2 17095214 9384557 Wrong interface of the dimer - automatic transfer from 2amv 2ieh_1 PROBNOT 1 1 NPS NPS 0 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2ieh_2 PROBNOT 1 1 NPS NPS 0 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2iei PROBYES 2 2 C2 C2 17095214 9384557 Wrong interface of the dimer - automatic transfer from 2amv 2ifb NO 1 1 NPS NPS 2671390 2671390 Paper says: large quantities of the native, monomeric protein can be produced in, and readily purified, from Escherichia coli. -- Annotation transfered from 1icm 2ifq_1 PROBYES 1 2 NPS C2 17260951 9369469 BU changed since last release and is now incorrect - SP says dimer, paper too, interface geometry conserved with 1nsw (36%) - monomer dimer equilibrium -- very interesting paper: quantification of the interface strengh according to the pH (> 10 fold difference). - automaticaly inferred from 1aiu 2ifq_2 PROBYES 1 2 NPS C2 17260951 9369469 BU changed since last release and is now incorrect - SP says dimer, paper too, interface geometry conserved with 1nsw (36%) - monomer dimer equilibrium -- very interesting paper: quantification of the interface strengh according to the pH (> 10 fold difference). - automaticaly inferred from 1aiu 2ifq_3 PROBYES 1 2 NPS C2 17260951 9369469 BU changed since last release and is now incorrect - SP says dimer, paper too, interface geometry conserved with 1nsw (36%) - monomer dimer equilibrium -- very interesting paper: quantification of the interface strengh according to the pH (> 10 fold difference). - automaticaly inferred from 1aiu 2ig9 NO 4 4 D2 D2 17446402 15028678 Interface geometry conserved with 1mpy (25%) - automatic transfer from 1f1x 2iga NO 4 4 D2 D2 17446402 15028678 Interface geometry conserved with 1mpy (25%) - automatic transfer from 1f1x 2igc NO 1 1 NPS NPS 17473014 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2igd PROBYES 1 1 NPS NPS 0 0 12379842 implies it is monomeric, PISA also says monomeric 2ih8_1 PROBNOT 1 1 NPS NPS 17045575 12118243 BU changed since last release and is now corrected - The crystal structure of the M. albomyces laccase (MaL) shows that the enzyme is a monomer - automaticaly inferred from 1gw0 2ih8_2 PROBNOT 1 1 NPS NPS 17045575 12118243 BU changed since last release and is now corrected - The crystal structure of the M. albomyces laccase (MaL) shows that the enzyme is a monomer - automaticaly inferred from 1gw0 2ih9_1 PROBNOT 1 1 NPS NPS 17045575 12118243 BU changed since last release and is now corrected - The crystal structure of the M. albomyces laccase (MaL) shows that the enzyme is a monomer - automaticaly inferred from 1gw0 2ih9_2 PROBNOT 1 1 NPS NPS 17045575 12118243 BU changed since last release and is now corrected - The crystal structure of the M. albomyces laccase (MaL) shows that the enzyme is a monomer - automaticaly inferred from 1gw0 2ihl NO 1 1 NPS NPS 8356074 0 2ihp PROBNOT 2 2 C2 C2 17260952 8994974 SP says dimer - automatic transfer from 1wgi 2ihq PROBNOT 1 1 NPS NPS 17181141 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 2iit NO 2 2 C2 C2 17055272 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2iiv NO 2 2 C2 C2 17055272 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2iiy PROBYES 1 2 NPS C2 17260951 9369469 BU changed since last release and is now incorrect - SP says dimer, paper too, interface geometry conserved with 1nsw (36%) - monomer dimer equilibrium -- very interesting paper: quantification of the interface strengh according to the pH (> 10 fold difference). - automaticaly inferred from 1aiu 2ij2_1 NA 1 1 NPS NPS 0 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 2ij2_2 NA 1 1 NPS NPS 0 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 2ij5_1 PROBNOT 1 1 NPS NPS 17028183 12435731 11304120 says P450s are monomeric enzymes - automatic transfer from 1n40 2ij5_2 PROBNOT 1 1 NPS NPS 17028183 12435731 11304120 says P450s are monomeric enzymes - automatic transfer from 1n40 2ij5_3 PROBNOT 1 1 NPS NPS 17028183 12435731 11304120 says P450s are monomeric enzymes - automatic transfer from 1n40 2ij5_4 PROBNOT 1 1 NPS NPS 17028183 12435731 11304120 says P450s are monomeric enzymes - automatic transfer from 1n40 2ij5_5 PROBNOT 1 1 NPS NPS 17028183 12435731 11304120 says P450s are monomeric enzymes - automatic transfer from 1n40 2ij5_6 PROBNOT 1 1 NPS NPS 17028183 12435731 11304120 says P450s are monomeric enzymes - automatic transfer from 1n40 2ij7_1 PROBNOT 1 1 NPS NPS 17028183 12435731 11304120 says P450s are monomeric enzymes - automatic transfer from 1n40 2ij7_2 PROBNOT 1 1 NPS NPS 17028183 12435731 11304120 says P450s are monomeric enzymes - automatic transfer from 1n40 2ij7_3 PROBNOT 1 1 NPS NPS 17028183 12435731 11304120 says P450s are monomeric enzymes - automatic transfer from 1n40 2ij7_4 PROBNOT 1 1 NPS NPS 17028183 12435731 11304120 says P450s are monomeric enzymes - automatic transfer from 1n40 2ij7_5 PROBNOT 1 1 NPS NPS 17028183 12435731 11304120 says P450s are monomeric enzymes - automatic transfer from 1n40 2ij7_6 PROBNOT 1 1 NPS NPS 17028183 12435731 11304120 says P450s are monomeric enzymes - automatic transfer from 1n40 2ijn_1 PROBNOT 1 1 NPS NPS 17049853 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2ijn_2 PROBNOT 1 1 NPS NPS 17049853 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2ik4 PROBNOT 2 2 C2 C2 17260952 8994974 SP says dimer - automatic transfer from 1wgi 2ikg NA 1 1 NPS NPS 17368668 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2ikh NA 1 1 NPS NPS 17368668 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2iki NA 1 1 NPS NPS 17368668 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2ikj NA 1 1 NPS NPS 17368668 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2ili PROBNOT 1 1 NPS NPS 0 8987974 9000633 says monomeric - automatic transfer from 1uga 2imm NO 2 2 C2 C2 1602480 1602480 -- Annotation transfered from 2imn 2imn NO 2 2 C2 C2 1602480 1602480 2in4 NO 1 1 NPS NPS 0 11935353 Myoglobin is well known to be monomeric - automatic transfer from 1gjn 2ine NA 1 1 NPS NPS 17083960 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2int PROBYES 2 1 C2 NPS 1400355 1400355 In a cell paper, binds receptor as a monomer (10219247)- in a JBC paper, purified as a monomer (7706290) - PISA says monomer -- Annotation transfered from 1hij 2inz NA 1 1 NPS NPS 17083960 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2ipw NA 1 1 NPS NPS 17083960 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2iq0 NA 1 1 NPS NPS 17083960 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2iqd NA 1 1 NPS NPS 17083960 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2irt_1 PROBNOT 1 1 NPS NPS 15299459 7867645 BU changed since last release and is now corrected - Paper says nothing, antagonist of a monomeric protein and PISA says monomer - automaticaly inferred from 1ilr 2irt_2 PROBNOT 1 1 NPS NPS 15299459 7867645 BU changed since last release and is now corrected - Paper says nothing, antagonist of a monomeric protein and PISA says monomer - automaticaly inferred from 1ilr 2isf NA 1 1 NPS NPS 17083960 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2isy PROBNOT 2 2 C2 C2 17209554 9887269 BU changed since last release and is now corrected - Interface conserved down to 30% with 1on1 - automaticaly inferred from 1b1b 2isz YES 4 2 C2 C2 17209554 9887269 BU changed since last release and is now incorrect - Interface conserved down to 30% with 1on1 - automaticaly inferred from 1b1b 2it0 YES 4 2 C2 C2 17209554 9887269 BU changed since last release and is now incorrect - Interface conserved down to 30% with 1on1 - automaticaly inferred from 1b1b 2it5 NA 1 1 NPS NPS 17150970 11739956 BU changed since last release and is now corrected - Seems that it is not really a monomer, but it is not really a dimer either - Paper says: The DC-SIGN crystals contain pairs of CRDs cross-linked by the oligosaccharide, in which one monomer forms the same contacts with the oligosaccharide observed for DC-SIGNR, while the partner monomer interacts with the terminal N-acetylglucosamine (GlcNAc) on the alpha 1-3 branch - automaticaly inferred from 1k9i 2it6 NA 1 1 NPS NPS 17150970 11739956 BU changed since last release and is now corrected - Seems that it is not really a monomer, but it is not really a dimer either - Paper says: The DC-SIGN crystals contain pairs of CRDs cross-linked by the oligosaccharide, in which one monomer forms the same contacts with the oligosaccharide observed for DC-SIGNR, while the partner monomer interacts with the terminal N-acetylglucosamine (GlcNAc) on the alpha 1-3 branch - automaticaly inferred from 1k9i 2itg NO 2 2 C2 C2 8977101 8977101 Often described as a dimer (sometimes tetramer), and convincingly a similar dimer (same interface) is found in 1a5v (30% id). -- Annotation transfered from 1itg 2itk PROBYES 1 2 NPS C2 0 10932246 Dimer according to PISA, and also according to me given the interface between the 2 polyp. chains in the ASU. But apparently no biochemical evidence. - automatic transfer from 1f8a 2itw NA 1 1 NPS NPS 0 12196540 The present data do not permit us to conclude that these contacts also arise in a cellular context - paper says that the protein may form dimers or even oligomers but they are not sure about these contacts - automatic transfer from 1m17 2itx NA 1 1 NPS NPS 0 12196540 The present data do not permit us to conclude that these contacts also arise in a cellular context - paper says that the protein may form dimers or even oligomers but they are not sure about these contacts - automatic transfer from 1m17 2ity NA 1 1 NPS NPS 0 12196540 The present data do not permit us to conclude that these contacts also arise in a cellular context - paper says that the protein may form dimers or even oligomers but they are not sure about these contacts - automatic transfer from 1m17 2ivi NA 1 1 NPS NPS 0 7791906 BU changed since last release and is now corrected - Might be interesting to discuss in the paper - So the difference in the two crystallised forms is a combination of the crystallisation conditions and the conformational change upon substrate binding. Biological significance? Intuitively, I would say - probably none I hope this helps, Cheers, Pete - automaticaly inferred from 1ips 2ivj NA 1 1 NPS NPS 0 7791906 BU changed since last release and is now corrected - Might be interesting to discuss in the paper - So the difference in the two crystallised forms is a combination of the crystallisation conditions and the conformational change upon substrate binding. Biological significance? Intuitively, I would say - probably none I hope this helps, Cheers, Pete - automaticaly inferred from 1ips 2iws PROBYES 1 2 NPS C2 17114002 9230303 BU changed since last release and is now incorrect - - automaticaly inferred from 1a4h 2iwu PROBYES 1 2 NPS C2 17114002 9230303 BU changed since last release and is now incorrect - - automaticaly inferred from 1a4h 2iwx PROBYES 1 2 NPS C2 17114002 9230303 BU changed since last release and is now incorrect - - automaticaly inferred from 1a4h 2ixc PROBYES 4 2 NS C2 17046787 12951098 BU changed since last release and is now incorrect - Interface geometry conserved with 1rtv (40%) - automaticaly inferred from 1pm7 2ixj PROBNOT 2 2 C2 C2 17046787 0 BU changed since last release and is now corrected - Interface geometry conserved with 1dzr (65%) - automaticaly inferred from 1rtv 2ixl_1 NO 2 2 C2 C2 17046787 12791259 Interface geometry conserved with 1rtv (65%) - automatic transfer from 1nxm 2ixl_2 NO 2 2 C2 C2 17046787 12791259 Interface geometry conserved with 1rtv (65%) - automatic transfer from 1nxm 2ixo_1 NA 1 1 NPS NPS 0 16885030 This protein behaves strangely: paper says: despite high residuals and broad c(s) peaks protein aggregation, we found for both proteins species s values compatible with monomers in the absence of ligand, and monomers and dimers in the presence of ligand. 2ixo_2 NA 1 1 NPS NPS 0 16885030 This protein behaves strangely: paper says: despite high residuals and broad c(s) peaks protein aggregation, we found for both proteins species s values compatible with monomers in the absence of ligand, and monomers and dimers in the presence of ligand. -- Annotation transfered from 2ixo_1 2ixp_1 NA 2 2 C2 C2 16885030 16885030 Paper says: Analytical ultracentrifugation demonstrates the presence of a monomer/dimer equilibrium in solution. The dimer seems to be triggered by a peptide. -- Annotation transfered from 2ixp_2 2ixp_2 NA 2 2 C2 C2 16885030 16885030 Paper says: Analytical ultracentrifugation demonstrates the presence of a monomer/dimer equilibrium in solution. The dimer seems to be triggered by a peptide. 2iyq PROBNOT 1 1 NPS NPS 17020768 12054870 SP says monomer - automatic transfer from 1l4u 2iyr_1 PROBNOT 1 1 NPS NPS 17020768 12054870 SP says monomer - automatic transfer from 1l4u 2iyr_2 PROBNOT 1 1 NPS NPS 17020768 12054870 SP says monomer - automatic transfer from 1l4u 2iys PROBNOT 1 1 NPS NPS 17020768 12054870 SP says monomer - automatic transfer from 1l4u 2iyt PROBNOT 1 1 NPS NPS 17020768 12054870 SP says monomer - automatic transfer from 1l4u 2iyu PROBNOT 1 1 NPS NPS 17020768 12054870 SP says monomer - automatic transfer from 1l4u 2iyv PROBNOT 1 1 NPS NPS 17020768 12054870 SP says monomer - automatic transfer from 1l4u 2iyw PROBNOT 1 1 NPS NPS 17020768 12054870 SP says monomer - automatic transfer from 1l4u 2iyx PROBNOT 1 1 NPS NPS 17020768 12054870 SP says monomer - automatic transfer from 1l4u 2iyy PROBNOT 1 1 NPS NPS 17020768 12054870 SP says monomer - automatic transfer from 1l4u 2iyz PROBNOT 1 1 NPS NPS 17020768 12054870 SP says monomer - automatic transfer from 1l4u 2iza NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2izb NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2izc NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2izd NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2ize NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2izf NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2izg NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2izh NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2izi NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2izj NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2izk YES 4 4 NS D2 9405158 9405158 2izl NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2j0d_1 PROBNOT 1 1 NPS NPS 16954191 15256616 Paper says nothing - 11304120 says P450s are monomeric enzymes - automatic transfer from 1w0e 2j0d_2 PROBNOT 1 1 NPS NPS 16954191 15256616 Paper says nothing - 11304120 says P450s are monomeric enzymes - automatic transfer from 1w0e 2j14_1 YES 1 2 NPS C2 16931011 10198642 BU changed since last release and is now incorrect - Either dimer or monomer but not not symmetrical dimer - automaticaly inferred from 3gwx 2j14_2 YES 1 2 NPS C2 16931011 10198642 BU changed since last release and is now incorrect - Either dimer or monomer but not not symmetrical dimer - automaticaly inferred from 3gwx 2j1m_1 NA 1 1 NPS NPS 0 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 2j1m_2 NA 1 1 NPS NPS 0 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 2j4f PROBYES 1 4 NPS NA 7981200 0 BU changed since last release and is now incorrect - BU changed since last release and is now incorrect - Very complex structure, QS changes with splicing variant and probably other factors. Investigate in more details for using it as an example. - automaticaly inferred from 1eea 2j4s_1 NA 1 1 NPS NPS 0 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 2j4s_2 NA 1 1 NPS NPS 0 16214136 BU changed since last release and is now corrected - Paper (not the one from the struct) says it can exist as a monomer (inactive) or dimer (active) so there is an equilibrium. But I hardly believe this small interface is the right one. I would be safer to let it as a monomer. - automaticaly inferred from 1jme 2j4z PROBYES 2 1 C2 NPS 17125279 12467573 BU changed since last release and is now incorrect - Paper does not mention oligomer - PISA says monomer - automaticaly inferred from 1mq4 2j50_1 PROBNOT 1 1 NPS NPS 17125279 12467573 Paper does not mention oligomer - PISA says monomer - automatic transfer from 1mq4 2j50_2 PROBNOT 1 1 NPS NPS 17125279 12467573 Paper does not mention oligomer - PISA says monomer - automatic transfer from 1mq4 2j5f NA 1 1 NPS NPS 17334377 12196540 The present data do not permit us to conclude that these contacts also arise in a cellular context - paper says that the protein may form dimers or even oligomers but they are not sure about these contacts - automatic transfer from 1m17 2j5k PROBNOT 4 4 D2 D2 17211074 0 BU changed since last release and is now corrected - SP says tetramer -- strange PISA says dimer - error? - automaticaly inferred from 1hlp 2j5q PROBNOT 4 4 D2 D2 17211074 0 BU changed since last release and is now corrected - SP says tetramer -- strange PISA says dimer - error? - automaticaly inferred from 1hlp 2j5r PROBNOT 4 4 D2 D2 17211074 0 BU changed since last release and is now corrected - SP says tetramer -- strange PISA says dimer - error? - automaticaly inferred from 1hlp 2j5x_1 PROBNOT 1 1 NPS NPS 11266366 10881192 PAper says nothing, PISA says monomer - automatic transfer from 1e0s 2j5x_2 PROBNOT 1 1 NPS NPS 11266366 10881192 PAper says nothing, PISA says monomer - automatic transfer from 1e0s 2j6m NA 1 1 NPS NPS 0 12196540 The present data do not permit us to conclude that these contacts also arise in a cellular context - paper says that the protein may form dimers or even oligomers but they are not sure about these contacts - automatic transfer from 1m17 2j7l NA 2 1 C2 NPS 17098869 2478891 BU changed since last release and is now incorrect - C alpha only (low resol) - automaticaly inferred from 3dpa 2j7x PROBYES 1 2 NPS C2 0 11250199 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - - automaticaly inferred from 1hj1 2j7y PROBYES 1 2 NPS C2 0 11250199 BU changed since last release and is now incorrect - BU changed since last release and is now corrected - - automaticaly inferred from 1hj1 2j7z PROBYES 2 1 C2 NPS 0 9618518 Chemokines are known to be predominantly in the monomeric form at physiological concentrations, and monomeric analogs are biologically active. Moreover, sedimentation equilibrium and NMR studies of SDF-1 have indicated that this chemokine is a monomer even at high concentrations. - automatic transfer from 1a15 2j8t NA 1 1 NPS NPS 0 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2j9a NO 6 6 D3 D3 17157838 8357796 Interface geometry conserved with 1gyt (30%) - automatic transfer from 1bll 2j9n PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1az8 2ja5 NO 12 12 NPS NPS 17290000 17290000 RNA Pol II complex 2ja6 NO 12 12 NPS NPS 17290000 17290000 RNA Pol II complex -- Annotation transfered from 2ja5 2ja7_1 NO 12 12 NPS NPS 17290000 17290000 RNA Pol II complex -- Annotation transfered from 2ja5 2ja7_2 NO 12 12 NPS NPS 17290000 17290000 RNA Pol II complex -- Annotation transfered from 2ja5 2ja8 NO 12 12 NPS NPS 17290000 17290000 RNA Pol II complex -- Annotation transfered from 2ja5 2jcw NO 2 2 C2 C2 10026301 10026301 SOD is a dimer 2jdo PROBNOT 1 1 NPS NPS 17275837 12434148 Paper says nothing about oligomer - PISA says monomer - automatic transfer from 1o6l 2jdr PROBNOT 1 1 NPS NPS 17275837 12434148 Paper says nothing about oligomer - PISA says monomer - automatic transfer from 1o6l 2jds NO 1 1 NPS NPS 0 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 2jdw NO 2 2 C2 C2 9218780 9218780 Paper says: The sedimentation analysis shows that AT and its mutants ATDelta M302 and ATDelta 11, as well as StrB1, form homodimers and that the mutations did not affect dimerization. 2jdx YES 2 2 NS C2 9915841 9915841 Paper says: The sedimentation analysis shows that AT and its mutants ATDelta M302 and ATDelta 11, as well as StrB1, form homodimers and that the mutations did not affect dimerization. -- Annotation transfered from 1jdx 2jev NO 2 2 C2 C2 17516632 0 Same dimer as 2b3u -- Annotation transfered from 2f5i 2jf2 NO 3 3 C3 C3 0 7481807 Interface geometry conserved with 1j2z (43%) - automatic transfer from 1lxa 2jf3 NO 3 3 C3 C3 0 7481807 Interface geometry conserved with 1j2z (43%) - automatic transfer from 1lxa 2jfc_1 NO 3 3 C3 C3 0 0 Active site at the monomer-monomer interface - automatic transfer from 1oe3 2jfc_2 NO 3 3 C3 C3 0 0 Active site at the monomer-monomer interface - automatic transfer from 1oe3 2jhf PROBNOT 2 2 C2 C2 0 9132002 BU changed since last release and is now corrected - - automaticaly inferred from 1lde 2jhg PROBNOT 2 2 C2 C2 0 9132002 BU changed since last release and is now corrected - - automaticaly inferred from 1lde 2jho NO 1 1 NPS NPS 17404234 0 Myoglobin is a monomeric protein (8663546) - automatic transfer from 1a6m 2jxr PROBNOT 1 1 NPS NPS 9135120 9135120 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1fq7 2kau NO 9 9 C3 C3 7754395 7754395 Interface geometry conserved with 4ubp (64% id avg) -- Annotation transfered from 1ejs 2kce NO 2 2 C2 C2 8939755 8939755 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 2knt PROBNOT 1 1 NPS NPS 9761897 9761897 SP says: Trimers composed of three different chains: alpha 1(VI), alpha 2(VI), and alpha 3(VI) 2l78 NO 1 1 NPS NPS 1569571 1569571 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 2lao PROBNOT 1 1 NPS NPS 8496186 8496186 Both papers do not mention a dimer - PISA says monomer -- Annotation transfered from 1lag 2lbd PROBNOT 1 1 NPS NPS 7501014 7501014 Do not talk about monomer nor dimer - PISA says monomer, they all crystallize as monomers so I assume they are really monomers. -- Annotation transfered from 1exa 2lbp PROBNOT 1 1 NPS NPS 2649683 2649683 EcoCyc shows that it is part of a larger complex and that it contributes one protein only. 2ldb NO 4 4 D2 D2 2330370 2330370 BU changed since last release and is now corrected - Paper, SP say tetramer 2ldx NO 4 4 D2 D2 2443489 2443489 BU changed since last release and is now corrected - SP says tetramer 2lgs NO 12 12 D6 D6 8099447 11329256 Salmonella typhimurium GS has a molecular mass of 620 kDa and is a dodecamer with 622 symmetry - automatic transfer from 1f1h 2lh1 PROBNOT 1 1 NPS NPS -1 0 SP says monomer -- Annotation transfered from 2gdm 2lh2 PROBNOT 1 1 NPS NPS -1 0 SP says monomer -- Annotation transfered from 2gdm 2lh3 PROBNOT 1 1 NPS NPS -1 0 SP says monomer -- Annotation transfered from 2gdm 2lh5 PROBNOT 1 1 NPS NPS -1 0 SP says monomer -- Annotation transfered from 2gdm 2lh6 PROBNOT 1 1 NPS NPS -1 0 SP says monomer -- Annotation transfered from 2gdm 2lh7 PROBNOT 1 1 NPS NPS -1 0 SP says monomer -- Annotation transfered from 2gdm 2lhb PROBNOT 1 1 NPS NPS 4032476 4032476 SP says: Monomer at high oxygen tension and high pH and dimeric at low oxygen tension and lower pH - induced dimerization 2lhm NO 1 1 NPS NPS 1939116 1939116 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2lig NO 2 2 C2 C2 1660187 1660187 Paper says dimer 2lip PROBNOT 1 1 NPS NPS 9032074 9032074 SP says monomer, PISA too -- Annotation transfered from 5lip 2lis PROBNOT 1 1 NPS NPS 10666624 10666624 Monomerization of the lysin dimer exposes the hydrophobic patch and allows it to interact with the VE glycoproteins. -- Annotation transfered from 1lis 2liv PROBNOT 1 1 NPS NPS 2649682 2649682 EcoCyc says monomer 2ljr NO 2 2 C2 C2 9551553 9551553 Interface geometry conserved with 1e6b (27%) -- Annotation transfered from 1ljr 2lpr NO 1 1 NPS NPS 1931963 1931963 9846867 says monomer -- Annotation transfered from 1p05 2lve NO 2 2 C2 C2 9739086 9739086 Interface conserved down to <30% (1cd8)! -- Annotation transfered from 1lve 2lym NO 1 1 NPS NPS 3586017 3586017 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 2lyo NO 1 1 NPS NPS 9659395 9659395 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 2lyz NO 1 1 NPS NPS 4856347 4856347 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 2lz2 NO 1 1 NPS NPS 0 0 -- Annotation transfered from 135l 2lzm NO 1 1 NPS NPS 3586019 3586019 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 2lzt NO 1 1 NPS NPS 2302327 2302327 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 2mas NO 4 4 D2 D2 9572842 9572842 Interface geometry conserved with 1ezr (78%) -- Annotation transfered from 1mas 2mbw NO 1 1 NPS NPS 8810310 8810310 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2mcg NO 2 2 C2 C2 2515285 2515285 -- Annotation transfered from 1a8j 2mcm PROBNOT 1 1 NPS NPS 2771945 0 No paper but PISA, PQS and PDB agree so I ll assume it is a monomer 2mea_1 YES 1 2 NPS NPS 10556244 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 2mea_2 YES 1 2 NPS NPS 10556244 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 2meb NO 1 1 NPS NPS 10556244 10556244 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2mec_1 YES 1 2 NPS NPS 10556244 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 2mec_2 YES 1 2 NPS NPS 10556244 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 2med NO 1 1 NPS NPS 10556244 10556244 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2mee NO 1 1 NPS NPS 10556244 10556244 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2mef NO 1 1 NPS NPS 10556244 10556244 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2meg NO 1 1 NPS NPS 10556244 10556244 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2meh NO 1 1 NPS NPS 10556244 10556244 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2mei NO 1 1 NPS NPS 10556244 10556244 Lysozyme C is monomeric -- Annotation transfered from 1lzr 2mga NO 1 1 NPS NPS 8230194 8230194 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2mgb NO 1 1 NPS NPS 8230194 8230194 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2mgc NO 1 1 NPS NPS 8230194 8230194 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2mgd NO 1 1 NPS NPS 8230194 8230194 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2mge NO 1 1 NPS NPS 8230194 8230194 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2mgf NO 1 1 NPS NPS 8230194 8230194 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2mgg NO 1 1 NPS NPS 8230194 8230194 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2mgh NO 1 1 NPS NPS 8230194 8230194 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2mgi NO 1 1 NPS NPS 8230194 8230194 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2mgj NO 1 1 NPS NPS 8230194 8230194 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2mgk NO 1 1 NPS NPS 8230194 8230194 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2mgl NO 1 1 NPS NPS 8230194 8230194 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2mgm NO 1 1 NPS NPS 8230194 8230194 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2mhr NO 1 1 NPS NPS 3681996 3681996 PAper says monomer: Monomeric analogues of hemerythrin and hemoglobin, found in muscle tissue, have been designated myohemerythrin and myoglobin -- Annotation transfered from 1a7d 2mib PROBNOT 1 1 NPS NPS 1807351 1807351 SP says monomer 2mip_1 NO 2 2 C2 C2 8378311 7613867 - automatic transfer from 1hii 2mip_2 NO 2 2 C2 C2 8378311 7613867 - automatic transfer from 1hii 2mjp NO 2 2 C2 C2 10404228 10404228 Both gel filtration and dynamic light-scattering studies show that Mj0226 protein forms a dimer under physiological conditions (data not shown). -- Annotation transfered from 1b78 2mm1 NO 1 1 NPS NPS 2342104 2342104 Myoglobin is well known to be monomeric 2mnr NO 8 8 D4 D4 1892834 1892834 Interface geometry conserved with 1sjb (24%) -- Annotation transfered from 1mns 2msb PROBNOT 2 2 C2 C2 1436090 1436090 Interface geometry conserved with 1rdk (>50%) - although the interface structure has changed. -- Annotation transfered from 1msb 2muc NO 8 8 D4 D4 10336378 10336378 Paper says octamer 2mya NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2myb NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2myc NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2myd NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2mye NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2nac NO 2 2 C2 C2 8114093 8114093 Interface geometry conserved with 1hku (31%) 2nad NO 2 2 C2 C2 8114093 8114093 Interface geometry conserved with 1hku (31%) -- Annotation transfered from 2nac 2ncd NO 2 2 C2 C2 9796817 9796817 Dimeric ncd with neck linker -- Annotation transfered from 1n6m 2nck NO 4 4 D2 D2 8263923 8263923 Equilibrium sedimentation studies are consistent with the enzyme being a tetramer in solution. 2nlr PROBNOT 1 1 NPS NPS 10200171 10200171 2nmn NO 1 1 NPS NPS 17327679 9582341 Paper says monomer - automatic transfer from 1a3k 2nmo NO 1 1 NPS NPS 17327679 9582341 Paper says monomer - automatic transfer from 1a3k 2nmt NO 1 1 NPS NPS 9846880 11371195 Paper says: This monomeric 455 residue enzyme has an ordered bi− bi reaction mechanism. Full characterization is in Towler, D.A. et al. Purification and characterization of myristoylCoA:protein N-myristoyltransferase. Proc. Natl. Acad. Sci. USA 84, 2708− 2712 (1987) (one of the rare case where PISA might be wrong while PDB is correct!) -- Annotation transfered from 1iid 2nmx_1 NO 1 1 NPS NPS 17407288 0 10529183 says monomer - automatic transfer from 1crm 2nmx_2 NO 1 1 NPS NPS 17407288 0 10529183 says monomer - automatic transfer from 1crm 2nn1_1 NO 1 1 NPS NPS 17407288 0 10529183 says monomer - automatic transfer from 1crm 2nn1_2 NO 1 1 NPS NPS 17407288 0 10529183 says monomer - automatic transfer from 1crm 2nn7_1 NO 1 1 NPS NPS 17407288 0 10529183 says monomer - automatic transfer from 1crm 2nn7_2 NO 1 1 NPS NPS 17407288 0 10529183 says monomer - automatic transfer from 1crm 2nn8 NO 1 1 NPS NPS 17327679 9582341 Paper says monomer - automatic transfer from 1a3k 2nng PROBNOT 1 1 NPS NPS 17407288 8987974 9000633 says monomeric - automatic transfer from 1uga 2nno PROBNOT 1 1 NPS NPS 17407288 8987974 9000633 says monomeric - automatic transfer from 1uga 2nnq PROBNOT 1 1 NPS NPS 17502136 15357970 PAper says nothing, PISA says monomer - automatic transfer from 1tou 2nns PROBNOT 1 1 NPS NPS 17407288 8987974 9000633 says monomeric - automatic transfer from 1uga 2nnu PROBYES 1 2 NPS C2 17189190 10693813 BU changed since last release and is now incorrect - Paper says: The E2NT module forms a dimer both in the crystal and in solution. - automaticaly inferred from 1dto 2nnv PROBNOT 1 1 NPS NPS 17407288 8987974 9000633 says monomeric - automatic transfer from 1uga 2nod_1 PROBYES 2 1 C2 NPS 9516116 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 2nod_2 PROBYES 2 1 C2 NPS 9516116 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 2nos PROBNOT 1 1 NPS NPS 9334294 9334294 Dimerization impaired -- very interesting case of dimerization inhibition. 2nph NO 2 2 C2 C2 17116869 9083478 - automatic transfer from 1ajx 2npx YES 1 4 NPS D2 8425532 8425532 Paper says it is tetrameric -- Annotation transfered from 1joa 2nqk NO 2 2 C2 C2 17198377 11428898 Interface geometry conserved with 1uz5 (34%) - automatic transfer from 1fc5 2nqm NO 2 2 C2 C2 17198377 11428898 Interface geometry conserved with 1uz5 (34%) - automatic transfer from 1fc5 2nqn NO 2 2 C2 C2 17198377 11428898 Interface geometry conserved with 1uz5 (34%) - automatic transfer from 1fc5 2nqq_1 NO 2 2 C2 C2 17198377 11428898 Interface geometry conserved with 1uz5 (34%) - automatic transfer from 1fc5 2nqq_2 NO 2 2 C2 C2 17198377 11428898 Interface geometry conserved with 1uz5 (34%) - automatic transfer from 1fc5 2nqr NO 2 2 C2 C2 17198377 11428898 Interface geometry conserved with 1uz5 (34%) - automatic transfer from 1fc5 2nqs NO 2 2 C2 C2 17198377 11428898 Interface geometry conserved with 1uz5 (34%) - automatic transfer from 1fc5 2nqu NO 2 2 C2 C2 17198377 11428898 Interface geometry conserved with 1uz5 (34%) - automatic transfer from 1fc5 2nqv NO 2 2 C2 C2 17198377 11428898 Interface geometry conserved with 1uz5 (34%) - automatic transfer from 1fc5 2nrd NO 3 3 C3 C3 7499203 7499203 2nro NO 2 2 C2 C2 17198377 11428898 Interface geometry conserved with 1uz5 (34%) - automatic transfer from 1fc5 2nrp NO 2 2 C2 C2 17198377 11428898 Interface geometry conserved with 1uz5 (34%) - automatic transfer from 1fc5 2nrs NO 2 2 C2 C2 17198377 11428898 Interface geometry conserved with 1uz5 (34%) - automatic transfer from 1fc5 2nse NO 2 2 C2 C2 9875848 9875848 Clear dimer -- Annotation transfered from 1fol 2nsi_1 PROBNOT 2 2 C2 C2 10409685 10409685 BU changed since last release and is now corrected - - automaticaly inferred from 1nsi 2nsi_2 PROBNOT 2 2 C2 C2 10409685 10409685 BU changed since last release and is now corrected - - automaticaly inferred from 1nsi 2ntg NO 1 1 NPS NPS 17473014 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2nth NO 1 1 NPS NPS 17473014 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2ntj PROBNOT 4 4 D2 D2 17227913 7886450 BU changed since last release and is now corrected - - automaticaly inferred from 1eny 2ntu PROBNOT 3 3 C3 C3 17141271 14532280 BU changed since last release and is now corrected - SP says trimer -- Duplicated chains - automaticaly inferred from 1vjm 2ntw YES 6 3 C3 C3 17141271 10514362 BU changed since last release and is now incorrect - SP says trimer - automaticaly inferred from 1c8r 2nuc NO 1 1 NPS NPS 8762134 8762134 Paper says monomeric -- Annotation transfered from 1ena 2nul PROBYES 2 1 C2 NPS 9268657 0 EcoCyc says monomer 2nuz PROBNOT 1 1 NPS NPS 0 15185962 - automatic transfer from 1neg 2nv6 PROBNOT 4 4 D2 D2 16906155 7886450 BU changed since last release and is now corrected - - automaticaly inferred from 1eny 2nvc NA 1 1 NPS NPS 17418233 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2nvd NA 1 1 NPS NPS 17418233 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2nvh PROBNOT 1 1 NPS NPS 17179045 0 SP says monomer - automatic transfer from 21bi 2nvq NO 10 10 NPS NPS 17129781 11313498 Correct complex. -- Annotation transfered from 1i3q 2nvt NO 10 10 NPS NPS 17129781 11313498 Correct complex. -- Annotation transfered from 1i3q 2nvx NO 10 10 NPS NPS 17129781 11313498 Correct complex. -- Annotation transfered from 1i3q 2nvy NO 10 10 NPS NPS 17129781 11313498 Correct complex. -- Annotation transfered from 1i3q 2nvz NO 10 10 NPS NPS 17129781 11313498 Correct complex. -- Annotation transfered from 1i3q 2nw4 PROBNOT 1 1 NPS NPS 17008401 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 2nwd YES 1 2 NPS NPS 17360367 10504240 BU changed since last release and is now incorrect - - automaticaly inferred from 1ckg 2nxc YES 1 2 NPS C2 17215866 0 No paper, but looking at the dimer it is certainly the right assembly (PISA) - automatic transfer from 1ufk 2nxe_1 YES 1 2 NPS C2 17215866 0 No paper, but looking at the dimer it is certainly the right assembly (PISA) - automatic transfer from 1ufk 2nxe_2 YES 1 2 NPS C2 17215866 0 No paper, but looking at the dimer it is certainly the right assembly (PISA) - automatic transfer from 1ufk 2nxj_1 YES 1 2 NPS C2 17215866 0 No paper, but looking at the dimer it is certainly the right assembly (PISA) - automatic transfer from 1ufk 2nxj_2 YES 1 2 NPS C2 17215866 0 No paper, but looking at the dimer it is certainly the right assembly (PISA) - automatic transfer from 1ufk 2nyb_1 NO 2 2 C2 C2 17628062 7849024 Paper says dimer - automatic transfer from 1isc 2nyb_2 NO 2 2 C2 C2 17628062 7849024 Paper says dimer - automatic transfer from 1isc 2o0u PROBNOT 1 1 NPS NPS 17194588 12954329 - automatic transfer from 1pmv 2o1n PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2o23 NA 4 4 D2 D2 0 15087549 BU changed since last release and is now corrected - I think it should be 4 subs, D2 sym, but PISA says D4 with 8 subs. A close rat homolog (>80%) has four subunits. Could be interesting to dig - automaticaly inferred from 1so8 2o2u PROBNOT 1 1 NPS NPS 17194588 12954329 - automatic transfer from 1pmv 2o2y NO 4 4 D2 D2 17327670 0 - automatic transfer from 1v35 2o4k NO 2 2 C2 C2 17360759 9083478 - automatic transfer from 1ajx 2o4p NO 2 2 C2 C2 17360759 9083478 - automatic transfer from 1ajx 2o4s NO 2 2 C2 C2 17360759 9083478 - automatic transfer from 1ajx 2o4z PROBNOT 1 1 NPS NPS 17346964 8987974 9000633 says monomeric - automatic transfer from 1uga 2o5d_1 PROBNOT 1 1 NPS NPS 17276060 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2o5d_2 PROBNOT 1 1 NPS NPS 17276060 12438577 BU changed since last release and is now corrected - BU changed since last release and is now incorrect - HCV RdRp exists primarily as a monomer - automaticaly inferred from 1gx6 2o7n PROBNOT 1 1 NPS NPS 17291752 7479767 BU changed since last release and is now corrected - Interface very small - probably monomer - automaticaly inferred from 1lfa 2o92 NO 1 1 NPS NPS 0 12529329 Elutes as a monomer - Papers says: The second peak in this final chromatographic step corresponded to a molecular mass of 40 kDa. - automatic transfer from 1ljy 2oa7 NO 2 2 C2 C2 0 9446594 - automatic transfer from 1bay 2oac NO 2 2 C2 C2 0 9446594 - automatic transfer from 1bay 2oad NO 2 2 C2 C2 0 9446594 - automatic transfer from 1bay 2oat PROBYES 4 2 C2 C2 9878407 9878407 Although the paper mentions an hexamer found in the crystal no evidence is shown that is exists in solution. -- Annotation transfered from 1oat 2oaz PROBNOT 1 1 NPS NPS 0 9812898 Paper says nothing, PISA says monomer - automatic transfer from 1b6a 2ocj_1 NA 1 4 NPS C2 17327663 8023157 BU changed since last release and is now incorrect - I am not sure about that one. 9628871 shows a cartoon of how it bind. Normally, there are 2 palindromic sequences, but in the crystal structure there are only 3 proteins, and the binding mode seems not compatible with that shown in 9628871 - automaticaly inferred from 1tsr 2ocj_2 NA 1 4 NPS C2 17327663 8023157 BU changed since last release and is now incorrect - I am not sure about that one. 9628871 shows a cartoon of how it bind. Normally, there are 2 palindromic sequences, but in the crystal structure there are only 3 proteins, and the binding mode seems not compatible with that shown in 9628871 - automaticaly inferred from 1tsr 2ocj_3 NA 1 4 NPS C2 17327663 8023157 BU changed since last release and is now incorrect - I am not sure about that one. 9628871 shows a cartoon of how it bind. Normally, there are 2 palindromic sequences, but in the crystal structure there are only 3 proteins, and the binding mode seems not compatible with that shown in 9628871 - automaticaly inferred from 1tsr 2ocj_4 NA 1 4 NPS C2 17327663 8023157 BU changed since last release and is now incorrect - I am not sure about that one. 9628871 shows a cartoon of how it bind. Normally, there are 2 palindromic sequences, but in the crystal structure there are only 3 proteins, and the binding mode seems not compatible with that shown in 9628871 - automaticaly inferred from 1tsr 2od8 NA 3 3 C3 C3 17308348 8001157 BU changed since last release and is now corrected - Should be a trimer - check the paper - automaticaly inferred from 1plr 2oe4 NO 1 1 NPS NPS 16269539 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2oe7 NO 1 1 NPS NPS 17292912 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2oe9 NO 1 1 NPS NPS 17292912 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2oea NO 1 1 NPS NPS 17292912 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2of2 PROBNOT 1 1 NPS NPS 17276681 10404594 - automatic transfer from 1qpc 2of4 PROBNOT 1 1 NPS NPS 17276681 10404594 - automatic transfer from 1qpc 2ofj_1 PROBNOT 1 1 NPS NPS 17503785 15134446 Paper says monomer - automatic transfer from 1fhv 2ofj_2 PROBNOT 1 1 NPS NPS 17503785 15134446 Paper says monomer - automatic transfer from 1fhv 2ofj_3 PROBNOT 1 1 NPS NPS 17503785 15134446 Paper says monomer - automatic transfer from 1fhv 2ofj_4 PROBNOT 1 1 NPS NPS 17503785 15134446 Paper says monomer - automatic transfer from 1fhv 2ofu PROBNOT 1 1 NPS NPS 16884310 10404594 - automatic transfer from 1qpc 2ofv PROBYES 2 1 NS NPS 16970394 10404594 BU changed since last release and is now incorrect - - automaticaly inferred from 1qpc 2og8_1 PROBNOT 1 1 NPS NPS 16970394 10404594 - automatic transfer from 1qpc 2og8_2 PROBNOT 1 1 NPS NPS 16970394 10404594 - automatic transfer from 1qpc 2ogz NO 2 2 C2 C2 17239592 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2oh0 NO 1 1 NPS NPS 17258463 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 2ohx NO 2 2 C2 C2 15299346 0 -- Annotation transfered from 8adh 2oj9 PROBNOT 1 1 NPS NPS 17317169 11694888 Fragment - Paper says: The IGF1 receptor is structurally homologous to the insulin receptor. Members of this receptor subfamily are heterotetrameric glycoproteins consisting of two extracellular ligand-binding alpha-subunits and two transmembrane catalytic beta-subunits. No dimer mentioned and PISA says monomer - automatic transfer from 1k3a 2ojf NO 1 1 NPS NPS 17258463 8003955 two alpha, two beta, alphas do not contact each others - automatic transfer from 1jlu 2ok1 PROBNOT 1 1 NPS NPS 17300186 12954329 - automatic transfer from 1pmv 2olh NO 1 1 NPS NPS 0 12529329 Elutes as a monomer - Papers says: The second peak in this final chromatographic step corresponded to a molecular mass of 40 kDa. - automatic transfer from 1ljy 2oli PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2olq NO 1 1 NPS NPS 17475535 12837799 Paper says: E. coli PCK is a monomeric, globular protein - automatic transfer from 1os1 2olr NO 1 1 NPS NPS 17475535 12837799 Paper says: E. coli PCK is a monomeric, globular protein - automatic transfer from 1os1 2om9_1 PROBYES 1 2 NPS C2 17462987 15258145 PISA says homodimer and identicals are homodimers - automatic transfer from 1wm0 2om9_2 PROBYES 1 2 NPS C2 17462987 15258145 PISA says homodimer and identicals are homodimers - automatic transfer from 1wm0 2om9_3 PROBYES 1 2 NPS C2 17462987 15258145 PISA says homodimer and identicals are homodimers - automatic transfer from 1wm0 2om9_4 PROBYES 1 2 NPS C2 17462987 15258145 PISA says homodimer and identicals are homodimers - automatic transfer from 1wm0 2omf NO 3 3 C3 C3 0 0 Interface geometry conserved with 1prn (20%) -- Annotation transfered from 1gfn 2one NO 2 2 C2 C2 9376357 8605183 Interface conserved with 1te6 (62% id) -- Annotation transfered from 1one 2oov_1 PROBNOT 2 2 C2 C2 17409383 15299901 BU changed since last release and is now corrected - Paper says dimer - automaticaly inferred from 1a2v 2oov_2 PROBNOT 2 2 C2 C2 17409383 15299901 BU changed since last release and is now corrected - Paper says dimer - automaticaly inferred from 1a2v 2oov_3 PROBNOT 2 2 C2 C2 17409383 15299901 BU changed since last release and is now corrected - Paper says dimer - automaticaly inferred from 1a2v 2op3_1 PROBNOT 1 1 NPS NPS 17469812 12641451 SP says monomer - automatic transfer from 1nqc 2op3_2 PROBNOT 1 1 NPS NPS 17469812 12641451 SP says monomer - automatic transfer from 1nqc 2oph NO 2 2 C2 C2 17350841 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2oqe_1 PROBNOT 2 2 C2 C2 17409383 15299901 BU changed since last release and is now corrected - Paper says dimer - automaticaly inferred from 1a2v 2oqe_2 PROBNOT 2 2 C2 C2 17409383 15299901 BU changed since last release and is now corrected - Paper says dimer - automaticaly inferred from 1a2v 2oqe_3 PROBNOT 2 2 C2 C2 17409383 15299901 BU changed since last release and is now corrected - Paper says dimer - automaticaly inferred from 1a2v 2oqi_1 NO 2 2 C2 C2 17367123 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2oqi_2 NO 2 2 C2 C2 17367123 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2oqn PROBNOT 1 1 NPS NPS 17452791 10504569 BU changed since last release and is now corrected - Thaumatin is a stable monomeric protein of 22kDa - automaticaly inferred from 1thw 2oqu PROBNOT 1 1 NPS NPS 17452791 9443341 - automatic transfer from 1c1m 2oqv NO 2 2 C2 C2 17367123 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2or1 PROBNOT 2 2 C2 C2 3187531 3187531 The repressor of phage 434 binds to a set of operator sites as a homodimer. -- Annotation transfered from 1per 2or3 PROBNOT 2 2 C2 C2 0 12914946 BU changed since last release and is now corrected - Homodimeric - automaticaly inferred from 1ps4 2osn PROBYES 1 3 NPS C3 17372360 16508078 BU changed since last release and is now incorrect - Paper says trimeric in solution - automaticaly inferred from 1g2x 2otc_1 PROBNOT 3 3 C3 C3 9275160 10747936 Paper says trimer: Anabolic OTCase is the simplest form of the enzyme, comprising a single homotrimeric unit - automatic transfer from 1duv 2otc_2 PROBNOT 3 3 C3 C3 9275160 10747936 Paper says trimer: Anabolic OTCase is the simplest form of the enzyme, comprising a single homotrimeric unit - automatic transfer from 1duv 2otc_3 PROBNOT 3 3 C3 C3 9275160 10747936 Paper says trimer: Anabolic OTCase is the simplest form of the enzyme, comprising a single homotrimeric unit - automatic transfer from 1duv 2otf PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2oth PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2otv PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1az8 2ou8 NO 1 1 NPS NPS 17473014 3681997 Phage T4 lysosyme is monomeric - automatic transfer from 1l10 2ou9 PROBNOT 1 1 NPS NPS 17473014 8503008 BU changed since last release and is now corrected - Phage T4 Lysosyme is monomeric - automaticaly inferred from 137l 2oub PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2ouz NO 2 2 C2 C2 17456742 9338790 paper says dimer - automatic transfer from 1err 2ovh PROBYES 1 2 NPS C2 17356170 15189034 BU changed since last release and is now incorrect - no info in paper, PISA says dimer - automaticaly inferred from 1sr7 2ovm PROBYES 1 2 NPS C2 17356170 15189034 BU changed since last release and is now incorrect - no info in paper, PISA says dimer - automaticaly inferred from 1sr7 2ovo NA 1 2 NPS NS 3971987 1870129 BU changed since last release and is now incorrect - - automaticaly inferred from 4ovo 2ovx_1 PROBNOT 1 1 NPS NPS 17599356 12051944 BU changed since last release and is now corrected - MMP9 appears to be able to form homodimers - automaticaly inferred from 1gkd 2ovx_2 PROBNOT 1 1 NPS NPS 17599356 12051944 BU changed since last release and is now corrected - MMP9 appears to be able to form homodimers - automaticaly inferred from 1gkd 2ovz_1 PROBNOT 1 1 NPS NPS 17599356 12051944 BU changed since last release and is now corrected - MMP9 appears to be able to form homodimers - automaticaly inferred from 1gkd 2ovz_2 PROBNOT 1 1 NPS NPS 17599356 12051944 BU changed since last release and is now corrected - MMP9 appears to be able to form homodimers - automaticaly inferred from 1gkd 2ow0_1 PROBNOT 1 1 NPS NPS 17599356 12051944 BU changed since last release and is now corrected - MMP9 appears to be able to form homodimers - automaticaly inferred from 1gkd 2ow0_2 PROBNOT 1 1 NPS NPS 17599356 12051944 BU changed since last release and is now corrected - MMP9 appears to be able to form homodimers - automaticaly inferred from 1gkd 2ow1_1 PROBNOT 1 1 NPS NPS 17599356 12051944 BU changed since last release and is now corrected - MMP9 appears to be able to form homodimers - automaticaly inferred from 1gkd 2ow1_2 PROBNOT 1 1 NPS NPS 17599356 12051944 BU changed since last release and is now corrected - MMP9 appears to be able to form homodimers - automaticaly inferred from 1gkd 2ow2_1 PROBNOT 1 1 NPS NPS 17599356 12051944 BU changed since last release and is now corrected - MMP9 appears to be able to form homodimers - automaticaly inferred from 1gkd 2ow2_2 PROBNOT 1 1 NPS NPS 17599356 12051944 BU changed since last release and is now corrected - MMP9 appears to be able to form homodimers - automaticaly inferred from 1gkd 2ow9_1 PROBNOT 1 1 NPS NPS 17623656 10074939 BU changed since last release and is now corrected - - automaticaly inferred from 456c 2ow9_2 PROBNOT 1 1 NPS NPS 17623656 10074939 BU changed since last release and is now corrected - - automaticaly inferred from 456c 2oxi NO 2 2 C2 C2 15299812 0 -- Annotation transfered from 8adh 2oxs PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1az8 2oy2_1 PROBNOT 1 1 NPS NPS 17096442 9655333 No clear evidence after a quick search but PISA agrees ... - automatic transfer from 1a85 2oy2_2 PROBNOT 1 1 NPS NPS 17096442 9655333 No clear evidence after a quick search but PISA agrees ... - automatic transfer from 1a85 2oy4_1 PROBNOT 1 1 NPS NPS 17096442 9655333 No clear evidence after a quick search but PISA agrees ... - automatic transfer from 1a85 2oy4_2 PROBNOT 1 1 NPS NPS 17096442 9655333 No clear evidence after a quick search but PISA agrees ... - automatic transfer from 1a85 2oyf PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2oz7 PROBNOT 1 1 NPS NPS 17311914 10840043 paper does not mention dimer and PISA says monomer - automatic transfer from 1e3g 2oz9 NO 2 2 C2 C2 3375234 0 - automatic transfer from 1jhg 2p23 PROBYES 2 1 NS NPS 17339340 14730967 BU changed since last release and is now incorrect - Paper says nothing, PISA says monomer - automaticaly inferred from 1pwa 2p2a PROBNOT 2 2 C2 C2 17455929 12015593 BU changed since last release and is now corrected - Paper says dimer (and shows it) - automaticaly inferred from 1lbb 2p2i_1 PROBNOT 1 1 NPS NPS 17253678 10368301 - automatic transfer from 1vr2 2p2i_2 PROBNOT 1 1 NPS NPS 17253678 10368301 - automatic transfer from 1vr2 2p2l PROBYES 3 1 C3 NPS 17452788 9033596 BU changed since last release and is now incorrect - Small G protein - Interacts with many proteins (SP) and may interact with itself as well --> monomer oligomer equilibrium (11134022) - automaticaly inferred from 1mh1 2p33 PROBNOT 1 1 NPS NPS 17459703 12954329 - automatic transfer from 1pmv 2p3b NO 2 2 C2 C2 17467738 9083478 - automatic transfer from 1ajx 2p3r_1 PROBNOT 4 4 D2 D2 17441732 9843423 BU changed since last release and is now corrected - - automaticaly inferred from 1bo5 2p3r_2 PROBNOT 4 4 D2 D2 17441732 9843423 BU changed since last release and is now corrected - - automaticaly inferred from 1bo5 2p4k NO 4 4 D2 D2 0 1394426 Paper says tetramer - automatic transfer from 1n0j 2p54 PROBNOT 1 1 NPS NPS 17243659 11587644 SP says: Heterodimer with the retinoid X receptor. - automatic transfer from 1i7g 2p70 PROBNOT 1 1 NPS NPS 0 10662696 BU changed since last release and is now corrected - - automaticaly inferred from 1dqe 2p71 PROBNOT 1 1 NPS NPS 0 10662696 BU changed since last release and is now corrected - - automaticaly inferred from 1dqe 2p8s NO 2 2 C2 C2 17433672 15175333 Paper says: It is characterized [...] as a soluble 210–290-kDa homodimeric form. - automatic transfer from 1tkr 2p9h NO 2 2 C2 C2 17543986 11601849 Dimer because tetramerization helix is missing - automatic transfer from 1jyf 2pab NO 4 4 D2 D2 671542 671542 transthyretin is tetrameric -- Annotation transfered from 1fh2 2pad PROBNOT 1 1 NPS NPS 952885 952885 Papain is a 23,400-dalton single polypeptide -- Annotation transfered from 9pap 2paf NO 2 2 C2 C2 17543986 11601849 Dimer because tetramerization helix is missing - automatic transfer from 1jyf 2pah NO 4 4 D2 D2 9642259 9642259 Interesting - link between oligom state and disease - Examination of the mutations causing PKU shows that some of the most frequent mutations are located at the interface of the catalytic and tetramerization domains. 2pal PROBNOT 1 1 NPS NPS 1880797 1880797 -- Annotation transfered from 1pal 2pb8 PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2pbg PROBNOT 1 1 NPS NPS 9223646 9223646 Paper says nothing about a dimer - PISA says monomer 2pbh PROBNOT 1 1 NPS NPS 8617355 8617355 SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond - here only one chain -- Annotation transfered from 1pbh 2pcb_2 PROBNOT 1 1 NPS NPS 1334573 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). - automatic transfer from 3ccp 2pcy PROBNOT 1 1 NPS NPS 6698995 6698995 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) 2pe0 NO 1 1 NPS NPS 17531483 15209375 gel filtration studies suggest that PDK1 is monomeric - automatic transfer from 1okz 2pe1 NO 1 1 NPS NPS 17531483 15209375 gel filtration studies suggest that PDK1 is monomeric - automatic transfer from 1okz 2pe2 NO 1 1 NPS NPS 17544272 15209375 gel filtration studies suggest that PDK1 is monomeric - automatic transfer from 1okz 2pel NO 4 4 C2 C2 8656429 8656429 Paper says tetramer 2pev NA 1 1 NPS NPS 0 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2pf8 NA 1 1 NPS NPS 0 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2pfh NA 1 1 NPS NPS 0 10882376 BU changed since last release and is now corrected - Swissprot and PISA say monomer - BUT PISA dimer of 1m9h (<40%) is similar to that one so I believe there might be some relevance to this crystal contact - given the orientation of the N/C terminis, Y2H could be interessting to test. 1afs also has a similar binding! -- interesting. - automaticaly inferred from 1ef3 2pfk_1 PROBYES 4 4 C2 D2 2527305 2975709 BU changed since last release and is now incorrect - 12015149: The eubacterial ATP-dependent PFKs, of which the E. coli enzyme is the best-studied example, are allosterically regulated homotetramers - automaticaly inferred from 1pfk 2pfl NO 2 2 C2 C2 10504733 10504733 -- Annotation transfered from 3pfl 2pg2 YES 2 1 C2 NPS 17498954 11328809 There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automatic transfer from 1ii6 2pgt NO 2 2 C2 C2 9245401 9245401 -- Annotation transfered from 9gss 2phh NO 2 2 C2 C2 2819062 3040401 the enzyme exists mainly as a dimer in solution 2phi PROBNOT 2 2 C2 C2 0 0 Papers of identical structures speak about the dimer as something relevant but it is interesting to note that two modes of dimerization exist among these proteins. I have not seen this discussed -- Annotation transfered from 1fx9 2phk PROBNOT 2 2 C2 C2 9362479 9362479 BU changed since last release and is now corrected - Paper says it is probably a dimer - PISA is wrong here (overlaping structures) - note that this kinase contains 4 copies of alpha,beta,gamma,delta! - interesting 2phy PROBNOT 1 1 NPS NPS 7756254 7756254 SP says monomer -- Annotation transfered from 1s1z 2pii NO 3 3 C3 C3 15299730 0 Interface geometry conserved with 1qy7 (66%) -- Annotation transfered from 1pil 2pil PROBYES 1 2 NPS NS 10048019 10048019 The protein forms filaments 2pk4 PROBNOT 1 1 NPS NPS 1657149 1657149 This is just a very small domain of much a larger protein so probably monomeric -- Annotation transfered from 1pk4 2pk5 PROBNOT 2 2 C2 C2 17581235 10651036 BU changed since last release and is now corrected - - automaticaly inferred from 3tlh 2pk6 PROBNOT 2 2 C2 C2 17581235 10651036 BU changed since last release and is now corrected - - automaticaly inferred from 3tlh 2pkc PROBNOT 1 1 NPS NPS 8083213 8083213 -- Annotation transfered from 1p7v 2plh YES 4 4 C4 D2 15299760 0 Paper implies so - PISa finds it. 2plt PROBNOT 1 1 NPS NPS 8399201 8027022 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) 2pmj PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2pmt_1 NO 2 2 C2 C2 9655824 9655824 Interface geometry conserved with 1e6b (29%) - automatic transfer from 1pmt 2pmt_2 NO 2 2 C2 C2 9655824 9655824 Interface geometry conserved with 1e6b (29%) - automatic transfer from 1pmt 2por NO 3 3 C3 C3 1328651 1328651 Interface geometry conserved with 1prn (28%) 2pq2 PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1p7v 2pri NO 2 2 C2 C2 7500360 7500360 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 2prj NO 2 2 C2 C2 8580837 8580837 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 2prk PROBNOT 1 1 NPS NPS 3271105 3271105 -- Annotation transfered from 1p7v 2prn NO 3 3 C3 C3 9684893 9684893 Interface geometry conserved with 1gfn (20%) -- Annotation transfered from 1prn 2prq NO 1 1 NPS NPS 17574677 10413478 Aminopeptidase from Aeromonas proteolytica (AAP) is a small, monomeric enzyme (32KDa) - automatic transfer from 1cp6 2psg PROBYES 2 2 C2 C2 2056534 2056534 They discuss the dimer in the paper. The enzyme is generally described as a monomer and I dont think this dimeric state is relevant as 2psg (99%) also forms a dimer but with a completely different config. -- Annotation transfered from 1psa 2psr NO 2 2 C2 C2 10026247 10026247 Paper says dimer 2ptk PROBNOT 1 1 NPS NPS 9405157 9405157 2ptn PROBNOT 1 1 NPS NPS -1 0 -- Annotation transfered from 1az8 2pvb PROBNOT 1 1 NPS NPS 10548066 10548066 -- Annotation transfered from 1pal 2pwa PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1p7v 2pwb PROBNOT 1 1 NPS NPS 0 0 - automatic transfer from 1p7v 2pws PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2pwz_1 NO 2 2 C2 C2 0 1507230 Paper says dimer - automatic transfer from 2cmd 2pwz_2 NO 2 2 C2 C2 0 1507230 Paper says dimer - automatic transfer from 2cmd 2py4 NO 3 3 C3 C3 0 15276840 Paper says: dUTPases are primarily homotrimeric and catalyze the metal ion dependent hydrolysis of dUTP to 2′-deoxyuridine 5′-monophosphate (dUMP) and pyrophosphate. - automatic transfer from 1snf 2pyc PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2pyp PROBNOT 1 1 NPS NPS 9045611 9045611 SP says monomer -- Annotation transfered from 1s1z 2pyr PROBNOT 1 1 NPS NPS 9506946 9506946 SP says monomer -- Annotation transfered from 1s1z 2q1n_1 YES 2 1 NS NPS 0 11932258 BU changed since last release and is now incorrect - Actin does not form closed dimer - automaticaly inferred from 1lcu 2q1n_2 YES 2 1 NS NPS 0 11932258 BU changed since last release and is now incorrect - Actin does not form closed dimer - automaticaly inferred from 1lcu 2q1p PROBNOT 1 1 NPS NPS 0 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1oxl 2q21 PROBYES 2 1 C2 NPS 1899707 1899707 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 2q31_1 YES 2 1 NS NPS 0 11932258 BU changed since last release and is now incorrect - Actin does not form closed dimer - automaticaly inferred from 1lcu 2q31_2 YES 2 1 NS NPS 0 11932258 BU changed since last release and is now incorrect - Actin does not form closed dimer - automaticaly inferred from 1lcu 2q36 YES 2 1 C2 NPS 0 11932258 Actin does not form closed dimer - automatic transfer from 1lcu 2q3m NA 2 1 C2 NPS 17850744 15317023 BU changed since last release and is now incorrect - Paper says nothing and PISA find a dimer with an large interface. - automaticaly inferred from 1q44 2q3v NA 4 4 D2 D2 17850744 0 No paper, no function, no name - automatic transfer from 1vm0 2q5a PROBYES 1 2 NPS C2 0 10932246 Dimer according to PISA, and also according to me given the interface between the 2 polyp. chains in the ASU. But apparently no biochemical evidence. - automatic transfer from 1f8a 2qr2 NO 2 2 C2 C2 10433694 10433694 -- Annotation transfered from 1qr2 2rac NO 1 1 NPS NPS 9860825 9860825 Amicyanin is a monomeric protein with a molecular weight of 15000 (Husain & Davidson, 1985) -- Annotation transfered from 1aaj 2ran PROBNOT 1 1 NPS NPS 8362244 8362244 SP and PISA say monomer - Probably monomeric in solution - However when bound to a 2d membranne, it forms trimeric assemblies: (PID 11099380) -- Annotation transfered from 1n42 2rap PROBNOT 1 1 NPS NPS 9312017 9312017 2rat NO 1 1 NPS NPS 1547232 1547232 -- Annotation transfered from 6rsa 2rdv_1 PROBNOT 1 1 NPS NPS 10089348 10089348 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes - automatic transfer from 1rdv 2rdv_2 PROBNOT 1 1 NPS NPS 10089348 10089348 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes - automatic transfer from 1rdv 2rdv_3 PROBNOT 1 1 NPS NPS 10089348 10089348 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes - automatic transfer from 1rdv 2reb ART 1 6 NPS NS 1731246 1731246 2ren PROBNOT 1 1 NPS NPS 2493678 2493678 2rhe NO 2 2 C2 C2 6876161 6876161 Non classic interface - Bence-Jones interaction 2rig YES 1 2 NPS C2 1939201 1939201 Domain swapped dimer but only the backbone is defined --> problem with PISA 2rla NO 3 3 C3 C3 9265637 9265637 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference -- Annotation transfered from 1hqx 2rma_1 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rma_10 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rma_2 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rma_3 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rma_4 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rma_5 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rma_6 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rma_7 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rma_8 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rma_9 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rmb_1 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rmb_10 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rmb_2 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rmb_3 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rmb_4 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rmb_5 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rmb_6 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rmb_7 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rmb_8 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rmb_9 PROBNOT 1 1 NPS NPS 8075981 8980234 Paper implies CypA is monomeric - automatic transfer from 5cyh 2rmc PROBYES 4 1 D2 NPS 8265636 8265636 Paper assume a monomer and PISa says monomer too 2rn2 PROBNOT 1 1 NPS NPS 1311386 1311386 SP says monomer -- Annotation transfered from 1f21 2rns NO 1 1 NPS NPS 1463719 1463719 -- Annotation transfered from 6rsa 2rom PROBNOT 1 1 NPS NPS 9334748 9334748 Paper does not mention oligomer - Crystallized many times as a monomer - PISA says monomer -- Annotation transfered from 1cmj 2rox NO 4 4 D2 D2 15299640 0 transthyretin is tetrameric -- Annotation transfered from 1fh2 2roy NO 4 4 D2 D2 15299640 0 transthyretin is tetrameric -- Annotation transfered from 1fh2 2rsl NO 6 6 C2 C2 8081753 8081753 Binds to 3 binding sites, each being formed by DNA inverted repeats. 2rta NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rtb NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rtc NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rtd NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rte NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rtf NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rtg NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rth NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rti NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rtj NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rtk NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rtl NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rtm NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rtn NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rto NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rtp NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rtq NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer -- Annotation transfered from 2rtr 2rtr NO 4 4 D2 D2 9405158 9405158 Streptavidin is well known to be a homotetramer 2rus NO 2 2 C2 C2 1899197 1899197 Paper says: In contrast to the hexadecameric plant enzyme, ribulose-P2 carboxylase from Rhodospirillum rubrum is a dimer of only large subunits. -- Annotation transfered from 1rus 2sak PROBNOT 2 2 C2 C2 9145104 11856331 BU changed since last release and is now corrected - The SAK dimer was detected by SDS/PAGE (15%), gel-filtration chromatography and MALDI-TOF mass spectroscopy. Gel-filtration analysis was carried out using a Superdex75 column (HR, 10/30, Amersham Pharmacia Biotech), eluting with 25 mm Tris/HCl, pH 8.0, 1 mm phenylmethanesulfonyl fluoride, 150 mm NaCl. The peak fractions were collected and analyzed by SDS/PAGE. The MALDI-TOF spectrum was obtained in positive ion mode with a Bruker BIFLEX III MALDI-TOF mass spectrometer using α-cyano-4-hydroxycinnamicbacid (CCA) as the matrix. -- however, they show an isologous interaction in the paper - automaticaly inferred from 1c77 2sam NO 2 2 C2 C2 8241141 8241141 -- Annotation transfered from 1az5 2sar_1 PROBNOT 1 1 NPS NPS 1654932 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 2sar_2 PROBNOT 1 1 NPS NPS 1654932 0 BU changed since last release and is now corrected - 11969396 says monomer - automaticaly inferred from 1gmp 2sba PROBNOT 4 4 D2 D2 7711015 7711015 -- Annotation transfered from 1sbd 2sbt NO 1 1 NPS NPS 4508127 4508127 -- Annotation transfered from 1yja 2sem PROBYES 2 1 C2 NPS 9851931 9851931 PISA says monomer and related proteins are monomeric -- Annotation transfered from 1sem 2shk PROBYES 2 1 C2 NPS 15299895 0 Paper says: This monomeric enzyme shows 53% amino-acid identity to E. coli SK II and, at less than 19 kD, is one of the smallest kinases so far described. -- Annotation transfered from 1e6c 2skc NO 2 2 C2 C2 8976550 8976550 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 2skd NO 2 2 C2 C2 8976550 8976550 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 2ske NO 2 2 C2 C2 8976550 8976550 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 2sn3 PROBNOT 1 1 NPS NPS 1522588 1522588 Paper says nothing and PISA says monomer -- Annotation transfered from 1jzb 2snm NO 1 1 NPS NPS 1920420 1920420 Paper says monomeric -- Annotation transfered from 1ena 2sns NO 1 1 NPS NPS 288045 288045 Paper says monomeric -- Annotation transfered from 1ena 2snv NA 1 1 NPS NPS 8450538 8450538 Unclear, email sent 2snw NO 2 2 C2 C2 8831786 8831786 Interface geometry conserved with 1vcq (68%) 2sod_1 NO 2 2 C2 C2 7175933 1619651 PAper, SP say dimer - automatic transfer from 1cob 2sod_2 NO 2 2 C2 C2 7175933 1619651 PAper, SP say dimer - automatic transfer from 1cob 2spl NO 1 1 NPS NPS 1629229 1629229 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2spm NO 1 1 NPS NPS 1629229 1629229 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2spn NO 1 1 NPS NPS 1629229 1629229 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2spo NO 1 1 NPS NPS 1629229 1629229 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 2sqc_1 PROBNOT 1 1 NPS NPS 9931258 9295270 Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer - automatic transfer from 1sqc 2sqc_2 PROBNOT 1 1 NPS NPS 9931258 9295270 Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer - automatic transfer from 1sqc 2src PROBNOT 1 1 NPS NPS 10360179 10360179 -- Annotation transfered from 2ptk 2st1 NO 1 1 NPS NPS 3286644 3286644 -- Annotation transfered from 1yja 2taa_1 PROBNOT 1 1 NPS NPS 6609921 1930835 SP says monomer - automatic transfer from 6taa 2taa_2 PROBNOT 1 1 NPS NPS 6609921 1930835 SP says monomer - automatic transfer from 6taa 2taa_3 PROBNOT 1 1 NPS NPS 6609921 1930835 SP says monomer - automatic transfer from 6taa 2tbs PROBNOT 1 1 NPS NPS 7846025 7846025 -- Annotation transfered from 1utm 2tcl PROBNOT 1 1 NPS NPS 7656013 7656013 No clear evidence after a quick search but PISA agrees ... -- Annotation transfered from 1hfc 2tdd NO 2 2 C2 C2 8343503 8343503 SP says homodimer -- Annotation transfered from 4tms 2tdm NO 2 2 C2 C2 8371269 8371269 SP says homodimer -- Annotation transfered from 4tms 2tdx NO 2 2 C2 C2 9697776 9697776 Interface geometry conserved down to 30% with 1on1 -- Annotation transfered from 1dpr 2tep NO 4 4 C2 C2 -1 0 Paper says tetramer -- Annotation transfered from 2pel 2tga PROBNOT 1 1 NPS NPS -1 0 -- Annotation transfered from 1az8 2tgd PROBNOT 1 1 NPS NPS 0 0 -- Annotation transfered from 1az8 2tgt PROBNOT 1 1 NPS NPS -1 0 -- Annotation transfered from 1az8 2tio PROBNOT 1 1 NPS NPS 9920392 9920392 -- Annotation transfered from 1az8 2tir NO 1 1 NPS NPS 8098620 8098620 Paper says: Gel-filtration chromatography and polyacrylamide gel electrophoresis suggest that CVWC Trx may exist as both monomers and dimers in solution. In contrast, analytical ultracentrifugation of the CVWC enzyme revealed no significant dimer formation in solution at concentrations up to 30 µM (data not shown). - likely monomer-dimer equilibrium -- Annotation transfered from 1txx 2tli PROBNOT 2 2 C2 C2 10651278 10651278 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 8tln 2tlx PROBNOT 1 1 NPS NPS 10651278 10651278 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 2tmk NO 2 2 C2 C2 9253404 9253404 Low similarity to other homodimers but interface geometry conserved 2tmn PROBNOT 2 2 C2 C2 3709536 3709536 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 8tln 2tmy NO 1 1 NPS NPS 9521117 9521117 Paper says monomer - very interesting paper btw -- Annotation transfered from 1tmy 2tn4 PROBNOT 1 1 NPS NPS 9438870 9438870 -- Annotation transfered from 1tcf 2tnf NO 3 3 C3 C3 10089307 10089307 Paper says trimer - Interface geometry conserved with 1tnf (80%) 2toh NO 4 4 D2 D2 9753429 9753429 Paper says tetramer - interesting: highly linked to disease. -- Annotation transfered from 1toh 2tpr NO 2 2 C2 C2 1924336 1924336 GR are homodimers -- Annotation transfered from 1typ 2trh NO 4 4 D2 D2 9818054 9818054 transthyretin is tetrameric -- Annotation transfered from 1fh2 2trm PROBNOT 1 1 NPS NPS 3112942 3112942 Trypsin is monomeric 2trs NO 4 4 C2 C2 9201907 9201907 Paper says a2b2 -- Annotation transfered from 2wsy 2trx_1 NO 1 1 NPS NPS 2181145 10489448 Paper says: Gel-filtration chromatography and polyacrylamide gel electrophoresis suggest that CVWC Trx may exist as both monomers and dimers in solution. In contrast, analytical ultracentrifugation of the CVWC enzyme revealed no significant dimer formation in solution at concentrations up to 30 µM (data not shown). - likely monomer-dimer equilibrium - automatic transfer from 1txx 2trx_2 NO 1 1 NPS NPS 2181145 10489448 Paper says: Gel-filtration chromatography and polyacrylamide gel electrophoresis suggest that CVWC Trx may exist as both monomers and dimers in solution. In contrast, analytical ultracentrifugation of the CVWC enzyme revealed no significant dimer formation in solution at concentrations up to 30 µM (data not shown). - likely monomer-dimer equilibrium - automatic transfer from 1txx 2try NO 4 4 D2 D2 9818054 9818054 transthyretin is tetrameric -- Annotation transfered from 1fh2 2tsa PROBYES 4 1 D2 NPS 15299604 0 This is hard to believe but it seems that azurin is a monomeric protein! -- Annotation transfered from 5azu 2tsb PROBYES 4 1 D2 NPS 15299604 0 This is hard to believe but it seems that azurin is a monomeric protein! -- Annotation transfered from 5azu 2tsc NO 2 2 C2 C2 2223754 2223754 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 2tsr_1 NO 2 2 C2 C2 9894005 9894005 SP says dimer - automatic transfer from 1rts 2tsr_2 NO 2 2 C2 C2 9894005 9894005 SP says dimer - automatic transfer from 1rts 2tsy NO 4 4 C2 C2 9201907 9201907 Paper says a2b2 -- Annotation transfered from 2wsy 2tun PROBYES 6 3 C2 C3 0 0 No paper - SP says trimer 2tys NO 4 4 C2 C2 9201907 9201907 Paper says a2b2 -- Annotation transfered from 2wsy 2ubp YES 3 9 NPS C3 10368287 10368287 Interface geometry conserved with 1e2f (64% id avg) -- Annotation transfered from 4ubp 2ucz PROBNOT 1 1 NPS NPS 9048545 9048545 Paper says nothing, PISA says monomer -- monomeric state seems consistent across the different homologous proteins. 2udp NO 2 2 C2 C2 8931134 8931134 SP says homodimer 2ull YES 16 1 NR NPS 9232638 9232638 2upj NO 2 2 C2 C2 7658450 7658450 -- Annotation transfered from 1ajx 2usn PROBNOT 1 1 NPS NPS 9792098 9792098 Stromelysin is secreted from cells as a 55- to 57-kDa monomeric proenzyme that, upon activation, loses 80 amino acids to yield a 45-kDa mature enzyme -- Annotation transfered from 1caq 2uw9 PROBNOT 1 1 NPS NPS 0 12434148 Paper says nothing about oligomer - PISA says monomer - automatic transfer from 1o6l 2uwd NA 2 1 C2 NPS 0 0 BU changed since last release and is now incorrect - 15217611 says: The HSP90 proteins have three domains. The C-terminal domain is the site for homodimerization of the proteins and contains binding sites for cochaperones. This is the Nter domain so I am not sure about the dimerization - automaticaly inferred from 1uy6 2uyi_1 PROBNOT 1 1 NPS NPS 17498954 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2uyi_2 PROBNOT 1 1 NPS NPS 17498954 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2uym_1 PROBNOT 1 1 NPS NPS 17498954 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2uym_2 PROBNOT 1 1 NPS NPS 17498954 11328809 BU changed since last release and is now corrected - There is no step during the walk where the kinesin could end-up in that position. Plus, if the dimerization domain was present, this would be prevented - automaticaly inferred from 1ii6 2v0a PROBNOT 2 2 C2 C2 17548825 12441104 BU changed since last release and is now corrected - Mammalian Cu,Zn SOD assembles into an unusually stable homodimer - automaticaly inferred from 1hl5 2v0m_1 PROBNOT 1 1 NPS NPS 16954191 15256616 Paper says nothing - 11304120 says P450s are monomeric enzymes - automatic transfer from 1w0e 2v0m_2 PROBNOT 1 1 NPS NPS 16954191 15256616 Paper says nothing - 11304120 says P450s are monomeric enzymes - automatic transfer from 1w0e 2v0m_3 PROBNOT 1 1 NPS NPS 16954191 15256616 Paper says nothing - 11304120 says P450s are monomeric enzymes - automatic transfer from 1w0e 2v0m_4 PROBNOT 1 1 NPS NPS 16954191 15256616 Paper says nothing - 11304120 says P450s are monomeric enzymes - automatic transfer from 1w0e 2v1e NO 1 1 NPS NPS 0 11935353 Myoglobin is well known to be monomeric - automatic transfer from 1gjn 2v1f NO 1 1 NPS NPS 0 11935353 Myoglobin is well known to be monomeric - automatic transfer from 1gjn 2v1g NO 1 1 NPS NPS 0 11935353 Myoglobin is well known to be monomeric - automatic transfer from 1gjn 2v1h NO 1 1 NPS NPS 0 11935353 Myoglobin is well known to be monomeric - automatic transfer from 1gjn 2v1i NO 1 1 NPS NPS 0 11935353 Myoglobin is well known to be monomeric - automatic transfer from 1gjn 2v1j NO 1 1 NPS NPS 0 11935353 Myoglobin is well known to be monomeric - automatic transfer from 1gjn 2v1k NO 1 1 NPS NPS 0 11935353 Myoglobin is well known to be monomeric - automatic transfer from 1gjn 2vao NO 8 8 D4 D4 9261083 9141139 Paper says octamer 2vhb NO 2 2 C2 C2 9115439 9115439 Paper says dimer -- interesting example to show a benchmark of what is a good interface because the interface with 5.5 resids is almost identical to that with 11!! Why is that? -- Annotation transfered from 1vhb 2vp3 YES 2 1 C2 NPS 9145102 9145102 SP and PISA say monomer -- Annotation transfered from 3mct 2vub YES 8 2 D4 C2 9917404 9917404 Paper says dimer: CcdB forms a dimer in the crystal, consistent with solution studies. 2wea YES 2 1 C2 NPS -1 0 It should be a monomer -- Annotation transfered from 2wec 2web YES 2 1 C2 NPS -1 0 It should be a monomer -- Annotation transfered from 2wec 2wec YES 2 1 C2 NPS -1 0 It should be a monomer 2wed YES 2 1 C2 NPS -1 0 It should be a monomer -- Annotation transfered from 2wec 2wsy NO 4 4 C2 C2 9548921 9548921 Paper says a2b2 2xat NO 3 3 C3 C3 9578552 9578552 Paper says trimer -- Annotation transfered from 1xat 2xim NO 4 4 D2 D2 1540579 1540579 -- Annotation transfered from 5xin 2xin NO 4 4 D2 D2 1610791 1610791 -- Annotation transfered from 5xin 2xis NO 4 4 D2 D2 2006134 2006134 -- Annotation transfered from 4xis 2xyl PROBYES 2 1 C2 NPS 9537990 0 Most protein in the family appear to be monomeric. Plus the crystal contact in the structure is very small. 2yas YES 1 2 NPS C2 10548044 10548044 PISA, SP, paper and I say homodimer -- Annotation transfered from 7yas 2ycc PROBNOT 1 1 NPS NPS 1311391 1311391 Cytochrome C may form disulfide bridged homodimers but most of the sequences are mutated so that it doesnt, or when not mutated it seems that no disulfide bond exists in the crystal anyway (cf. 1chh) - In order to prevent the formation of covalent homodimers during subsequent analyses, the further replacement of Cys 102 by a threonine was made. It has been shown that this latter replacement is neutral in terms of the structural andfunctional characteristics of yeast iso-1 cytochrome c (PID 7757009) -- Annotation transfered from 1crh 2yfp NO 1 1 NPS NPS 9782051 9782051 SP says monomeric - In fact its state depends on the environment ([.], pH etc ...) - PMID 9759496 says: The excitation spectrum of wild-type GFP changes its shape as a function of protein concentration, implying some form of aggregation - monomer dimer equilibrium -- Annotation transfered from 1oxe 2ypi NO 2 2 C2 C2 2204418 2204418 Interface geometry conserved with 1m6j (43%) -- Annotation transfered from 7tim 2yu9 NO 10 10 NPS NPS 17129781 11313498 Correct complex. -- Annotation transfered from 1i3q 2yvb NO 1 1 NPS NPS 0 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 2yvc_1 PROBNOT 1 1 NPS NPS 0 10970839 May exist in equilibrium between monomers and oligomers: 10893267 - interesting - automatic transfer from 1gc7 2yvc_2 PROBNOT 1 1 NPS NPS 0 10970839 May exist in equilibrium between monomers and oligomers: 10893267 - interesting - automatic transfer from 1gc7 2yvc_3 PROBNOT 1 1 NPS NPS 0 10970839 May exist in equilibrium between monomers and oligomers: 10893267 - interesting - automatic transfer from 1gc7 2ywp PROBNOT 1 1 NPS NPS 16446090 12244092 paper: fractions containing a monomeric form of Chk1 were pooled and concentrated to about 7 mg/ml for crystallization - automatic transfer from 1nvs 2znb_1 PROBNOT 1 1 NPS NPS 9416622 9730812 BU changed since last release and is now corrected - - automaticaly inferred from 1a7t 2znb_2 PROBNOT 1 1 NPS NPS 9416622 9730812 BU changed since last release and is now corrected - - automaticaly inferred from 1a7t 2znc PROBYES 2 1 C2 NPS 9541386 9541386 10529183 says monomer, PISA too -- Annotation transfered from 3znc 2zta NO 2 2 C2 C2 1948029 1948029 Paper says dimer -- Annotation transfered from 1zil 31bi PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 21bi 3aat NO 2 2 C2 C2 1993208 1993208 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 3aid NO 2 2 C2 C2 8894111 8894111 -- Annotation transfered from 1ajx 3aig PROBYES 2 1 C2 NPS 9521103 7583637 In monomeric metzincins, such as crayfish astacin and adamalysin II 3aky PROBNOT 1 1 NPS NPS 7635152 7635152 SP and PISA say monomer -- Annotation transfered from 2aky 3amv NO 2 2 C2 C2 10548038 10548038 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 3app NO 1 1 NPS NPS 6341600 6341600 -- Annotation transfered from 1bxo 3at1 NO 12 12 D3 D3 2405902 2405902 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 3atj PROBYES 2 1 C2 NPS 0 0 SP says monomer 3azu PROBYES 4 1 D2 NPS 1901363 1901363 This is hard to believe but it seems that azurin is a monomeric protein! -- Annotation transfered from 5azu 3bc2 NO 1 1 NPS NPS 0 0 -- Annotation transfered from 1bvt 3bjl NO 2 2 C2 C2 8692936 8692936 The three identical structures have a different dimeric packing! cf. paper -- interessting -- Annotation transfered from 1bjm 3blg PROBNOT 1 1 NPS NPS 9760236 9760236 SP says: Under physiological conditions beta-lactoglobulin exists as an equilibrium mixture of monomeric and dimeric forms -- Annotation transfered from 1gxa 3blm PROBYES 2 1 C2 NPS 2005620 2005620 Class A betalactamase are apparently monomeric in solution (said in paper) -- Annotation transfered from 1kgf 3bls_1 PROBNOT 1 1 NPS NPS 9819201 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 3bls_2 PROBNOT 1 1 NPS NPS 9819201 10595535 BU changed since last release and is now corrected - AmpC is a class C beta Lactamase and those are monomeric (12951239) - automaticaly inferred from 1c3b 3bp2 PROBNOT 1 1 NPS NPS 6466614 6466614 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1o2e 3bto_1 PROBNOT 2 2 C2 C2 9003191 9132002 BU changed since last release and is now corrected - - automaticaly inferred from 1lde 3bto_2 PROBNOT 2 2 C2 C2 9003191 9132002 BU changed since last release and is now corrected - - automaticaly inferred from 1lde 3c2c PROBNOT 1 1 NPS NPS -1 0 3ca2 PROBNOT 1 1 NPS NPS 3151020 3151020 9000633 says monomeric -- Annotation transfered from 1uga 3cao NO 1 1 NPS NPS 10398589 10398589 Paper says: No molecular association was observed with or without Zn, at low protein concentration (1.7 μM) with either cacodylate (pH 5.6) or Tris-HCl (pH 7.6) buffer. - PISa says monomer too -- interesting case as in some cytochromes, there is an induced dimerization by Zn ions (refs in paper) 3car NO 1 1 NPS NPS 10398589 10398589 Paper says: No molecular association was observed with or without Zn, at low protein concentration (1.7 μM) with either cacodylate (pH 5.6) or Tris-HCl (pH 7.6) buffer. - PISa says monomer too -- interesting case as in some cytochromes, there is an induced dimerization by Zn ions (refs in paper) -- Annotation transfered from 3cao 3cbh PROBNOT 1 1 NPS NPS 2377893 2377893 PISA problem: low resolution - similar proteins appear monomeric so I assume this one should be too 3cbs NO 1 1 NPS NPS 10531482 9737849 Apo-CRABPII is largely monomeric in solution 3ccp PROBNOT 1 1 NPS NPS 2169873 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). 3ccx PROBNOT 1 1 NPS NPS 8664277 8664277 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 3cd2 PROBNOT 1 1 NPS NPS 10194348 10194348 PISA also says monomer - Human is monomeric so I guess it should be - Only Thermogota seems to be dimeric -- Annotation transfered from 1cd2 3cd4 PROBYES 2 1 C2 NPS 8254672 8986758 By analytical ultracentrifugation at comparable concentrations, gp120 and CD4 alone were shown to behave as monomers and form a 1:1 complex when mixed (P. Hensley, personal communication), which suggests that self-association was not the root of the deviations. - This doesnt show for sure that there is no association since CD4 is normally in a membranne - But since PISA says monomer, I ll stick to this 3cel PROBNOT 1 1 NPS NPS 8951380 8951380 None of the papers speaks about a dimer - a dimer is found using PISA but visual inspection reveals a weak interface. -- Annotation transfered from 6cel 3cev_1 YES 6 6 D3 D3 10196128 10196128 Interface geometry conserved with 1gq6 (28%) -- bad interface -- interesting as the geometry of the trimers varies. - automatic transfer from 1cev 3cev_2 YES 6 6 D3 D3 10196128 10196128 Interface geometry conserved with 1gq6 (28%) -- bad interface -- interesting as the geometry of the trimers varies. - automatic transfer from 1cev 3cgt NO 1 1 NPS NPS 9558324 9558324 Paper says monomeric: Cyclodextrin glycosyltransferases (CGTases, EC 2.4.1.19) are of bacterial origin and are monomeric. They catalyze the -- Annotation transfered from 7cgt 3chy NO 1 1 NPS NPS 1869568 1869568 CheY is a Mr 14,000 monomeric protein -- Annotation transfered from 1chn 3cla PROBNOT 3 3 C3 C3 2187098 2187098 SP says trimer -- PISA very wrong 3cln PROBNOT 1 1 NPS NPS 3145979 3145979 3cna PROBNOT 4 4 D2 D2 4638345 4638345 -- Annotation transfered from 1cn1 3cp4 PROBNOT 1 1 NPS NPS 1742281 1742281 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 3cpp PROBNOT 1 1 NPS NPS 2611203 2611203 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 3cro YES 2 1 C2 NPS 2038059 9174359 Apparently monomeric (said in the reference) 3crx PROBNOT 4 4 C4 C4 9670032 9670032 BU changed since last release and is now corrected - -- symmetry search error? 3csc NO 2 2 C2 C2 2043640 2043640 Interface geometry conserved with 1a59 (27%) -- Annotation transfered from 6cts 3csu NO 3 3 C3 C3 10318893 10318893 -- Annotation transfered from 1gq3 3cyh PROBNOT 1 1 NPS NPS 8652512 8652512 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 3cyr NO 1 1 NPS NPS -1 0 Paper says: Tetraheme cytochrome c(3) is a small soluble and monomeric protein that performs a central step in the bioenergetic metabolism of sulfate reducing bacteria - PISA says monomer too -- Annotation transfered from 1gm4 3cyt_1 PROBNOT 1 1 NPS NPS 6256733 0 - automatic transfer from 5cyt 3cyt_2 PROBNOT 1 1 NPS NPS 6256733 0 - automatic transfer from 5cyt 3daa NO 2 2 C2 C2 9538014 9538014 Homodimer -- Annotation transfered from 2daa 3dap NO 2 2 C2 C2 9521647 9521647 Paper says dimer -- Annotation transfered from 2dap 3dbv NO 4 4 D2 D2 9175858 9175858 SP says homotetramer - papers too -- Annotation transfered from 1npt 3dfr PROBNOT 1 1 NPS NPS 6815178 6815178 SP says monomer 3dhe NO 2 2 C2 C2 10625652 10625652 Paper says dimer 3dni NA 2 2 C2 C2 3560229 3560229 3dpa NA 1 1 NPS NPS 2478891 2478891 C alpha only (low resol) 3drc PROBYES 2 1 C2 NPS 1932031 1932031 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1dds 3ebx NA 1 1 NPS NPS 3272151 3272151 All papers are useless impossible to find an answer %$@~# -- Annotation transfered from 5ebx 3enl NO 2 2 C2 C2 2405163 8605183 Interface conserved with 1te6 (62% id) -- Annotation transfered from 1one 3enr YES 2 4 C2 D2 11092923 11092923 -- Annotation transfered from 1qgl 3er3 PROBNOT 1 1 NPS NPS 6381096 6381096 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 3er5 PROBNOT 1 1 NPS NPS 8424781 6381096 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 3era NA 2 2 C2 C2 10691969 10691969 All papers are useless impossible to find an answer %$@~# -- Annotation transfered from 1qkd 3erd NO 2 2 C2 C2 9875847 9875847 paper says dimer -- Annotation transfered from 1err 3erk PROBNOT 1 1 NPS NPS 9753691 9753691 -- Annotation transfered from 4erk 3ert NO 2 2 C2 C2 9875847 9875847 paper says dimer -- Annotation transfered from 1err 3est PROBNOT 1 1 NPS NPS 3271103 3271103 -- Annotation transfered from 1c1m 3ezm YES 1 2 NPS C2 10329150 10329150 Domain swapped dimer 3fbp NO 4 4 D2 D2 2157849 2157849 -- Annotation transfered from 1eyi 3fib PROBNOT 1 1 NPS NPS 9207064 9016719 BU changed since last release and is now corrected - Paper doesnt speak about this dimer - automaticaly inferred from 1fic 3fiv NO 2 2 C2 C2 9271500 9271500 3fua NO 4 4 C4 C4 8676381 0 -- Annotation transfered from 1e4a 3fx2 PROBNOT 1 1 NPS NPS 2002503 2002503 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1f4p 3fyg NO 2 2 C2 C2 9698551 9698551 3gal_1 PROBNOT 1 1 NPS NPS 9760227 9760227 BU changed since last release and is now corrected - Paper says: The hGal-7 molecule crystallizes as a dimer, although in solution it is known to exist as a monomer unlike most other mammalian galectins, except Gal-10 (6). - automaticaly inferred from 5gal 3gal_2 PROBNOT 1 1 NPS NPS 9760227 9760227 BU changed since last release and is now corrected - Paper says: The hGal-7 molecule crystallizes as a dimer, although in solution it is known to exist as a monomer unlike most other mammalian galectins, except Gal-10 (6). - automaticaly inferred from 5gal 3gar PROBYES 2 2 C2 C2 9698564 9698564 Paper says: E. coli GarTfase exhibits a pH-dependent monomer-dimer equilibrium with the monomer preferably populated above pH 7.4 and the dimer below pH 6.6 -- BUT this one contains a mutation at the interface that prevent dimer formation even at low pH. 3gbp NA 1 2 NPS C2 1967096 1967096 Ecocyc says it forms dimers but I am not sure whether this may require some additional domain like a transmembrane helix? -- Annotation transfered from 1glg 3gcb NO 6 6 D3 D3 9546396 9546396 SP says hexamer and interface geometry conserved with 1cb5 (38%) 3gch NA 2 1 C2 NPS 2364065 2364065 They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 3gct NA 4 1 C2 NPS 1888717 1888717 BU changed since last release and is now incorrect - They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 3gpb NO 2 2 C2 C2 2125493 2125493 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) 3gpd NO 4 4 D2 D2 957435 957435 SP says tetramer - papers too 3grs NO 2 2 C2 C2 3656429 3656429 Paper says dimer -- Annotation transfered from 5grt 3grt NO 2 2 C2 C2 2059620 9174360 Paper says dimer -- Annotation transfered from 5grt 3gsb NO 2 2 C2 C2 9144156 9144156 Paper says dimer -- Annotation transfered from 2gsa 3gss NO 2 2 C2 C2 9012673 9012673 -- Annotation transfered from 9gss 3gst NO 2 2 C2 C2 8110735 8110735 -- Annotation transfered from 6gsv 3gwx YES 2 2 NS C2 10198642 10198642 Either dimer or monomer but not not symmetrical dimer 3hts PROBYES 2 1 C2 NPS 10331875 10331875 The protein is made of a DNA BD and a trimerization domain. Since the trimerization is not part of the structure I guess it should be a monomer 3hud NO 2 2 C2 C2 1896463 1896463 Dimer of identical or non-identical chains of three types - gene dup - interesting -- Annotation transfered from 1hdx 3hvp NO 2 2 C2 C2 2548279 2548279 -- Annotation transfered from 1ajx 3icb NO 1 1 NPS NPS 3722173 11316872 Paper says monomer 3il8 PROBNOT 2 2 C2 C2 1988949 1988949 Paper says dimer - but a monomer-dimer equilibrium seems to exist 3ink PROBYES 2 1 NS NPS 1631562 0 3jdw NO 2 2 C2 C2 9218780 9218780 Paper says: The sedimentation analysis shows that AT and its mutants ATDelta M302 and ATDelta 11, as well as StrB1, form homodimers and that the mutations did not affect dimerization. -- Annotation transfered from 2jdw 3kar NO 1 1 NPS NPS 9485302 9485302 Missing dimerization coil-coil 3kiv PROBNOT 1 1 NPS NPS 10026282 10026282 Real protein 4500 aa! So monomeric seems right - paper says nothing - PISA says monomeric 3kvt NO 4 4 C4 C4 9886290 9886290 Interface geometry conserved with 1t1d (41%) 3lad NO 2 2 C2 C2 1880807 1880807 Paper says dimer 3lbd PROBNOT 1 1 NPS NPS 9501913 9501913 Do not talk about monomer nor dimer - PISA says monomer, they all crystallize as monomers so I assume they are really monomers. -- Annotation transfered from 1exa 3lck PROBNOT 1 1 NPS NPS 8945479 8945479 -- Annotation transfered from 1qpc 3lhb_1 PROBYES 2 1 C2 NPS 10378271 4032476 BU changed since last release and is now incorrect - SP says: Monomer at high oxygen tension and high pH and dimeric at low oxygen tension and lower pH - induced dimerization - automaticaly inferred from 2lhb 3lhb_2 PROBYES 2 1 C2 NPS 10378271 4032476 BU changed since last release and is now incorrect - SP says: Monomer at high oxygen tension and high pH and dimeric at low oxygen tension and lower pH - induced dimerization - automaticaly inferred from 2lhb 3lhb_3 PROBYES 2 1 C2 NPS 10378271 4032476 BU changed since last release and is now incorrect - SP says: Monomer at high oxygen tension and high pH and dimeric at low oxygen tension and lower pH - induced dimerization - automaticaly inferred from 2lhb 3lhb_4 PROBYES 2 1 C2 NPS 10378271 4032476 BU changed since last release and is now incorrect - SP says: Monomer at high oxygen tension and high pH and dimeric at low oxygen tension and lower pH - induced dimerization - automaticaly inferred from 2lhb 3lhb_5 PROBYES 2 1 C2 NPS 10378271 4032476 BU changed since last release and is now incorrect - SP says: Monomer at high oxygen tension and high pH and dimeric at low oxygen tension and lower pH - induced dimerization - automaticaly inferred from 2lhb 3lhb_6 PROBYES 2 1 C2 NPS 10378271 4032476 BU changed since last release and is now incorrect - SP says: Monomer at high oxygen tension and high pH and dimeric at low oxygen tension and lower pH - induced dimerization - automaticaly inferred from 2lhb 3lhm NO 1 1 NPS NPS 1939116 1939116 Lysozyme C is monomeric -- Annotation transfered from 1lzr 3lip PROBNOT 1 1 NPS NPS 9032074 9032074 SP says monomer, PISA too -- Annotation transfered from 5lip 3ljr NO 2 2 C2 C2 9551553 9551553 Interface geometry conserved with 1e6b (27%) -- Annotation transfered from 1ljr 3lpr NO 1 1 NPS NPS 1931963 1931963 9846867 says monomer -- Annotation transfered from 1p05 3lve NO 2 2 C2 C2 9739086 9739086 Interface conserved down to <30% (1cd8)! -- Annotation transfered from 1lve 3lym NO 1 1 NPS NPS 3586017 3586017 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 3lyn NO 2 2 C2 C2 10698629 10698629 Interface geometry conserved with 1lyn (64%) 3lyo NO 1 1 NPS NPS 9659395 9659395 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 3lyt_1 NO 1 1 NPS NPS -1 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 3lyt_2 NO 1 1 NPS NPS -1 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 3lyz NO 1 1 NPS NPS 4856347 4856347 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 3lz2 NO 1 1 NPS NPS 1515108 1515108 -- Annotation transfered from 135l 3lzm NO 1 1 NPS NPS 2674124 2674124 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 3lzt NO 1 1 NPS NPS 9761848 9761848 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 3mag YES 2 1 C2 NPS 10377383 10377383 SP and PISA say monomer -- Annotation transfered from 3mct 3mba NO 1 1 NPS NPS 2926816 2926816 Myoglobin is well known to be monomeric -- Annotation transfered from 2fal 3mbp PROBNOT 1 1 NPS NPS 9309217 9309217 EcoCyc says monomer -- Annotation transfered from 1nl5 3mcg YES 4 2 C2 C2 2515285 2515285 3mct YES 2 1 C2 NPS 10377383 10377383 SP and PISA say monomer 3mds NO 4 4 D2 D2 2038060 2038060 Paper says tetramer - the tetramer has essentially the same geometry as the human SOD (1em1). However the nature of the interfaces has changed -- very interesting example of interface evolution! 3muc NO 8 8 D4 D4 10336378 10336378 Paper says octamer -- Annotation transfered from 2muc 3nll PROBNOT 1 1 NPS NPS 9063874 9063874 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 2fdx 3nod_1 PROBYES 2 1 C2 NPS 9516116 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 3nod_2 PROBYES 2 1 C2 NPS 9516116 9334294 BU changed since last release and is now incorrect - Dimerization impaired -- very interesting case of dimerization inhibition. - automaticaly inferred from 1nos 3nos NO 2 2 C2 C2 10074942 10074942 Clear dimer -- Annotation transfered from 1m9r 3nse NO 2 2 C2 C2 9875848 9875848 Clear dimer -- Annotation transfered from 1fol 3nuc NO 1 1 NPS NPS 8762134 8762134 Paper says monomeric -- Annotation transfered from 1ena 3nul PROBNOT 1 1 NPS NPS 9016723 9016723 SP says: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio -- Annotation transfered from 1a0k 3orc NO 1 1 NPS NPS 9684880 9684880 Engineered monomer 3p2p PROBNOT 2 2 C2 C2 2704992 2704992 SP says Monomer or homodimer, Acylation causes dimerization. Paper doent say if this dimer is relevant or not - PISA says dimer -- Annotation transfered from 5p2p 3pah YES 1 2 NPS C2 9843368 9843368 They speak of the: dimeric catalytic domain (residues 117-424) - Even though the tetramerization helix is missing, it should still be a dimer. -- Annotation transfered from 1dmw 3pal PROBNOT 1 1 NPS NPS 1880797 1880797 -- Annotation transfered from 1pal 3paz NO 1 1 NPS NPS 9341204 9341204 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 -- Annotation transfered from 8paz 3pbg_1 PROBNOT 1 1 NPS NPS 9223646 9223646 Paper says nothing about a dimer - PISA says monomer - automatic transfer from 2pbg 3pbg_2 PROBNOT 1 1 NPS NPS 9223646 9223646 Paper says nothing about a dimer - PISA says monomer - automatic transfer from 2pbg 3pbh PROBNOT 1 1 NPS NPS 8617355 8617355 SP says: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond - here only one chain -- Annotation transfered from 1pbh 3pcy PROBNOT 1 1 NPS NPS 3941073 3941073 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) -- Annotation transfered from 2pcy 3pep PROBNOT 1 1 NPS NPS 2217165 2217165 Pepsin genaraly described as a monomer. -- Annotation transfered from 4pep 3pfk NO 4 4 D2 D2 6115424 6115424 12015149: The eubacterial ATP-dependent PFKs, of which the E. coli enzyme is the best-studied example, are allosterically regulated homotetramers -- Annotation transfered from 6pfk 3pfl NO 2 2 C2 C2 10504733 10504733 3pgh_1 NO 2 2 C2 C2 8967954 10811226 - automatic transfer from 1cvu 3pgh_2 NO 2 2 C2 C2 8967954 10811226 - automatic transfer from 1cvu 3pgm NO 4 4 D2 D2 6115412 0 BU changed since last release and is now corrected - 11038361 and SP say tetramer 3pgt NO 2 2 C2 C2 10441116 10441116 -- Annotation transfered from 9gss 3phv NO 2 2 C2 C2 2682266 2682266 -- Annotation transfered from 1ajx 3pnp NO 3 3 C3 C3 0 0 Paper says trimer -- Annotation transfered from 1v48 3por NO 3 3 C3 C3 7685826 7685826 Interface geometry conserved with 1prn (28%) -- Annotation transfered from 2por 3prg NA 1 2 NPS C2 9813012 9813012 Strange: they say: PPARgamma does not form functional homodimers - ? others say homodimer who to believe? - interesting 3prk PROBNOT 1 1 NPS NPS 1894649 1894649 -- Annotation transfered from 1p7v 3prn NO 3 3 C3 C3 9684893 9684893 Interface geometry conserved with 1gfn (20%) -- Annotation transfered from 1prn 3psg PROBNOT 1 1 NPS NPS 1594574 1594574 Pepsin genaraly described as a monomer. -- Annotation transfered from 4pep 3psr NO 2 2 C2 C2 10026247 10026247 Paper says dimer -- Annotation transfered from 2psr 3ptb PROBNOT 1 1 NPS NPS -1 0 -- Annotation transfered from 1az8 3pte PROBNOT 1 1 NPS NPS 7490745 0 the Streptomyces R61 and Actinomadura R39 DD-peptidases, are water-soluble monomeric proteins; (12723972) -- Annotation transfered from 1pwd 3ptn PROBNOT 1 1 NPS NPS -1 0 -- Annotation transfered from 1az8 3pyp PROBNOT 1 1 NPS NPS 9515969 9515969 SP says monomer -- Annotation transfered from 1s1z 3ran_1 PROBYES 1 2 NPS C2 9878368 9878368 BU changed since last release and is now incorrect - Paper says dimer - automaticaly inferred from 1byu 3ran_2 PROBYES 1 2 NPS C2 9878368 9878368 BU changed since last release and is now incorrect - Paper says dimer - automaticaly inferred from 1byu 3ran_3 PROBYES 1 2 NPS C2 9878368 9878368 BU changed since last release and is now incorrect - Paper says dimer - automaticaly inferred from 1byu 3ran_4 PROBYES 1 2 NPS C2 9878368 9878368 BU changed since last release and is now incorrect - Paper says dimer - automaticaly inferred from 1byu 3rap PROBYES 2 1 C2 NPS 10591105 10591105 3rat NO 1 1 NPS NPS 1547232 1547232 -- Annotation transfered from 6rsa 3rla NO 3 3 C3 C3 9265637 9265637 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference -- Annotation transfered from 1hqx 3rn3 NO 1 1 NPS NPS 2619965 2619965 -- Annotation transfered from 6rsa 3rp2 PROBYES 2 1 C2 NPS 3233198 3233198 3rsd NO 1 1 NPS NPS 9636030 9636030 -- Annotation transfered from 6rsa 3rsk NO 1 1 NPS NPS 9860854 9860854 3rsp NO 1 1 NPS NPS 9684895 9684895 -- Annotation transfered from 6rsa 3sdh NO 2 2 C2 C2 8289287 8289287 Paper and SP say dimer -- Annotation transfered from 7hbi 3sdp NO 2 2 C2 C2 2271564 2271564 Paper and SP say dimer 3seb NO 1 1 NPS NPS 9514739 9514739 SEB is monomeric -- Annotation transfered from 1se3 3sem_1 PROBNOT 1 1 NPS NPS 9851931 7802869 BU changed since last release and is now corrected - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1sem 3sem_2 PROBNOT 1 1 NPS NPS 9851931 7802869 BU changed since last release and is now corrected - PISA says monomer and related proteins are monomeric - automaticaly inferred from 1sem 3sqc_1 PROBNOT 1 1 NPS NPS 9931258 9295270 Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer - automatic transfer from 1sqc 3sqc_2 PROBNOT 1 1 NPS NPS 9931258 9295270 Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer - automatic transfer from 1sqc 3sqc_3 PROBNOT 1 1 NPS NPS 9931258 9295270 Paper does not mention a trimer - a human protein homologue is active as a monomer (15525992) and PISA says monomer - automatic transfer from 1sqc 3tgl PROBNOT 1 1 NPS NPS -1 2046751 BU changed since last release and is now corrected - Bad structure (only CA) - automaticaly inferred from 5tgl 3tim PROBNOT 2 2 C2 C2 2062827 2062827 SP says dimer -- Annotation transfered from 6tim 3tlh YES 1 2 NPS C2 10651036 10651036 3tli PROBNOT 2 2 C2 C2 10651278 10651278 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 8tln 3tmk_1 NO 2 2 C2 C2 9521686 9253404 Low similarity to other homodimers but interface geometry conserved - automatic transfer from 2tmk 3tmk_2 NO 2 2 C2 C2 9521686 9253404 Low similarity to other homodimers but interface geometry conserved - automatic transfer from 2tmk 3tmk_3 NO 2 2 C2 C2 9521686 9253404 Low similarity to other homodimers but interface geometry conserved - automatic transfer from 2tmk 3tmk_4 NO 2 2 C2 C2 9521686 9253404 Low similarity to other homodimers but interface geometry conserved - automatic transfer from 2tmk 3tmn PROBNOT 1 1 NPS NPS 3343246 3343246 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 3tms NO 2 2 C2 C2 2128651 2128651 SP and EcoCyc say dimer -- Annotation transfered from 1ev8 3tmy_1 NO 1 1 NPS NPS 9521117 9521117 Paper says monomer - very interesting paper btw - automatic transfer from 1tmy 3tmy_2 NO 1 1 NPS NPS 9521117 9521117 Paper says monomer - very interesting paper btw - automatic transfer from 1tmy 3ubp YES 3 9 NPS C3 10368287 10368287 Interface geometry conserved with 1e2f (64% id avg) -- Annotation transfered from 4ubp 3ull PROBNOT 4 4 D2 D2 9033597 0 Structure very close to 1eqq (~33% id). So probably relevant 3upj NO 2 2 C2 C2 7658450 7658450 -- Annotation transfered from 1hii 3vhb NO 2 2 C2 C2 10448042 10448042 Paper says dimer -- interesting example to show a benchmark of what is a good interface because the interface with 5.5 resids is almost identical to that with 11!! Why is that? -- Annotation transfered from 1vhb 3vsb NO 1 1 NPS NPS 9425066 9425066 -- Annotation transfered from 1be6 3vub NO 2 2 C2 C2 9917404 9917404 Paper says dimer: CcdB forms a dimer in the crystal, consistent with solution studies. 3wrp NO 2 2 C2 C2 3375234 3375234 -- Annotation transfered from 1jhg 3xim NO 4 4 D2 D2 1540579 1540579 -- Annotation transfered from 5xin 3xin NO 4 4 D2 D2 1610791 1610791 -- Annotation transfered from 5xin 3xis NO 4 4 D2 D2 2006134 2006134 -- Annotation transfered from 4xis 3yas YES 1 2 NPS C2 10548044 10548044 PISA, SP, paper and I say homodimer -- Annotation transfered from 7yas 3ygs PROBNOT 2 2 NS NS 10376594 10376594 Paper says dimer 3ypi NO 2 2 C2 C2 2007138 2007138 Interface geometry conserved with 1m6j (43%) -- Annotation transfered from 7tim 3znb_1 PROBNOT 1 1 NPS NPS 9416622 9730812 BU changed since last release and is now corrected - - automaticaly inferred from 1a7t 3znb_2 PROBNOT 1 1 NPS NPS 9416622 9730812 BU changed since last release and is now corrected - - automaticaly inferred from 1a7t 3znc PROBYES 2 1 C2 NPS 9541386 9541386 10529183 says monomer, PISA too 41bi PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 21bi 421p PROBYES 2 1 C2 NPS 2199064 2199064 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 456c PROBYES 2 1 C2 NPS 10074939 10074939 4aig PROBYES 2 1 C2 NPS 9428736 9428736 In monomeric metzincins, such as crayfish astacin and adamalysin II -- Annotation transfered from 3aig 4ake PROBYES 2 1 C2 NPS 8805521 0 SP and EcoCyc say monomer 4ape PROBNOT 1 1 NPS NPS 6381096 6381096 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 4at1 NO 12 12 D3 D3 2271528 2271528 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 4atj_1 PROBNOT 1 1 NPS NPS 12351824 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1gx2 4atj_2 PROBNOT 1 1 NPS NPS 12351824 0 BU changed since last release and is now corrected - SP says monomer - automaticaly inferred from 1gx2 4azu PROBYES 4 1 D2 NPS 1942029 1942029 This is hard to believe but it seems that azurin is a monomeric protein! -- Annotation transfered from 5azu 4bjl NO 2 2 C2 C2 8692936 8692936 The three identical structures have a different dimeric packing! cf. paper -- interessting -- Annotation transfered from 1bjm 4blc NO 4 4 D2 D2 10417406 10417406 Interface geometry conserved with 1mqf (50% id) 4blm_1 PROBNOT 1 1 NPS NPS 1856867 11827533 BU changed since last release and is now corrected - Paper says nothing and PISA says monomeric - automaticaly inferred from 1i2w 4blm_2 PROBNOT 1 1 NPS NPS 1856867 11827533 BU changed since last release and is now corrected - Paper says nothing and PISA says monomeric - automaticaly inferred from 1i2w 4bp2 PROBNOT 1 1 NPS NPS 1793547 1793547 Not any paper of an apparently dimeric form discusses the dimer - plus the pancreatic form is accepted to be monomeric in solution -- Annotation transfered from 1o2e 4ca2 PROBNOT 1 1 NPS NPS 1932029 1932029 9000633 says monomeric -- Annotation transfered from 1uga 4cac PROBNOT 1 1 NPS NPS 3151019 3151019 9000633 says monomeric -- Annotation transfered from 1uga 4ccp PROBNOT 1 1 NPS NPS 2169873 2169873 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 4ccx PROBNOT 1 1 NPS NPS 8664277 8664277 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 4cd2 PROBNOT 1 1 NPS NPS 10194348 10194348 PISA also says monomer - Human is monomeric so I guess it should be - Only Thermogota seems to be dimeric -- Annotation transfered from 1cd2 4cel_1 PROBNOT 1 1 NPS NPS 8951380 9466911 None of the papers speaks about a dimer - a dimer is found using PISA but visual inspection reveals a weak interface. - automatic transfer from 6cel 4cel_2 PROBNOT 1 1 NPS NPS 8951380 9466911 None of the papers speaks about a dimer - a dimer is found using PISA but visual inspection reveals a weak interface. - automatic transfer from 6cel 4cev_1 YES 6 6 D3 D3 10196128 10196128 Interface geometry conserved with 1gq6 (28%) -- bad interface -- interesting as the geometry of the trimers varies. - automatic transfer from 1cev 4cev_2 YES 6 6 D3 D3 10196128 10196128 Interface geometry conserved with 1gq6 (28%) -- bad interface -- interesting as the geometry of the trimers varies. - automatic transfer from 1cev 4cgt NO 1 1 NPS NPS 9738912 9738912 Paper says monomeric: Cyclodextrin glycosyltransferases (CGTases, EC 2.4.1.19) are of bacterial origin and are monomeric. They catalyze the -- Annotation transfered from 7cgt 4cha NA 4 1 C2 NPS 4046030 4046030 BU changed since last release and is now incorrect - They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). 4cla PROBNOT 3 3 C3 C3 2015231 2015231 SP says trimer -- PISA very wrong -- Annotation transfered from 3cla 4cln PROBNOT 1 1 NPS NPS 1939171 1939171 -- Annotation transfered from 3cln 4cox_1 NO 2 2 C2 C2 8967954 10811226 - automatic transfer from 1cvu 4cox_2 NO 2 2 C2 C2 8967954 10811226 - automatic transfer from 1cvu 4cp4 PROBNOT 1 1 NPS NPS 1742281 1742281 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 4cpp PROBNOT 1 1 NPS NPS 2001355 2001355 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 4cpv PROBNOT 2 2 C2 C2 2334704 2334704 Sedimentation equilibrium analysis results show that the EF fragment exists in a monomer-dimer equilibrium when complexed with La3+ // This symmetry is conserved with 1b8c. Not very clear though -- Annotation transfered from 5cpv 4crx YES 4 8 C4 C4 10377382 10377382 BU changed since last release and is now incorrect - -- Annotation transfered from 1kbu 4csc NO 2 2 C2 C2 2043640 2043640 Interface geometry conserved with 1a59 (27%) -- Annotation transfered from 6cts 4csm YES 2 2 C2 C2 9384560 9384560 Wrong dimer reconstructed 4cts NO 2 2 C2 C2 6716477 6716477 Interface geometry conserved with 1a59 (27%) -- Annotation transfered from 6cts 4cyh PROBNOT 1 1 NPS NPS 8652512 8652512 Paper implies CypA is monomeric -- Annotation transfered from 5cyh 4daa NO 2 2 C2 C2 9538014 9538014 Homodimer -- Annotation transfered from 2daa 4dbv NO 4 4 D2 D2 9175858 9175858 SP says homotetramer - papers too -- Annotation transfered from 1npt 4dcg PROBNOT 1 1 NPS NPS 10377383 10377383 SP and PISA say monomer -- Annotation transfered from 1eam 4dfr PROBYES 2 1 C2 NPS 6815178 6815178 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1dds 4enl NO 2 2 C2 C2 -1 8605183 Interface conserved with 1te6 (62% id) -- Annotation transfered from 1one 4er1 PROBNOT 1 1 NPS NPS 6381096 6381096 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 4er2 PROBNOT 1 1 NPS NPS 6381096 6381096 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 4er4 PROBNOT 1 1 NPS NPS 3295561 3295561 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 4erk PROBNOT 1 1 NPS NPS 9753691 9753691 4est PROBNOT 1 1 NPS NPS -1 0 -- Annotation transfered from 1c1m 4fbp NO 4 4 D2 D2 1850623 1850623 -- Annotation transfered from 1eyi 4fgf PROBNOT 1 1 NPS NPS 7691311 7691311 SP says monomer -- Annotation transfered from 1bas 4fiv NO 2 2 C2 C2 9827997 9827997 -- Annotation transfered from 3fiv 4fua NO 4 4 C4 C4 8676381 8676381 -- Annotation transfered from 1e4a 4fx2 PROBNOT 1 1 NPS NPS 2002503 2002503 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1f4p 4fxc PROBNOT 1 1 NPS NPS 8586613 8586613 Paper says nothing, PISA says monomer 4gal YES 2 1 C2 NPS 9760227 9760227 Paper says: The hGal-7 molecule crystallizes as a dimer, although in solution it is known to exist as a monomer unlike most other mammalian galectins, except Gal-10 (6). -- Annotation transfered from 5gal 4gch NA 4 1 C2 NPS 2364065 2364065 BU changed since last release and is now incorrect - They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 4gcr PROBNOT 1 1 NPS NPS 15299528 0 y-Crystallins are exclusively monomeric -- Annotation transfered from 1gcs 4gpb NO 2 2 C2 C2 2125493 2125493 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 4gpd NO 4 4 D2 D2 7411626 7411626 4gr1 NO 2 2 C2 C2 2355009 2355009 Paper says dimer -- Annotation transfered from 5grt 4grt NO 2 2 C2 C2 9174360 9174360 Paper says dimer -- Annotation transfered from 5grt 4gsa NO 2 2 C2 C2 9144156 9144156 Paper says dimer -- Annotation transfered from 2gsa 4gss NO 2 2 C2 C2 9166793 9166793 -- Annotation transfered from 9gss 4gst NO 2 2 C2 C2 8241147 8241147 -- Annotation transfered from 6gsv 4hbi NO 2 2 C2 C2 9826511 9826511 Paper and SP say dimer -- Annotation transfered from 7hbi 4hvp NO 2 2 C2 C2 2686029 2686029 -- Annotation transfered from 1ajx 4i1b PROBNOT 1 1 NPS NPS 1553379 1553379 SP says monomer -- Annotation transfered from 21bi 4icb NO 1 1 NPS NPS 1542107 1542107 Paper says monomer -- Annotation transfered from 3icb 4jdw NO 2 2 C2 C2 9218780 9218780 Paper says: The sedimentation analysis shows that AT and its mutants ATDelta M302 and ATDelta 11, as well as StrB1, form homodimers and that the mutations did not affect dimerization. -- Annotation transfered from 2jdw 4kiv PROBNOT 1 1 NPS NPS 10026282 10026282 Real protein 4500 aa! So monomeric seems right - paper says nothing - PISA says monomeric -- Annotation transfered from 3kiv 4lbd PROBNOT 1 1 NPS NPS 9501913 9501913 Do not talk about monomer nor dimer - PISA says monomer, they all crystallize as monomers so I assume they are really monomers. -- Annotation transfered from 1exa 4lip_1 PROBNOT 1 1 NPS NPS 9660188 9660188 SP says monomer, PISA too - automatic transfer from 5lip 4lip_2 PROBNOT 1 1 NPS NPS 9660188 9660188 SP says monomer, PISA too - automatic transfer from 5lip 4lve NO 2 2 C2 C2 9739086 9739086 Interface conserved down to <30% (1cd8)! -- Annotation transfered from 1lve 4lym NO 1 1 NPS NPS 2398048 2398048 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 4lyo NO 1 1 NPS NPS 9659395 9659395 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 4lyt_1 NO 1 1 NPS NPS -1 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 4lyt_2 NO 1 1 NPS NPS -1 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 4lyz NO 1 1 NPS NPS 4856347 4856347 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 4lzm NO 1 1 NPS NPS 2062826 2062826 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 4lzt NO 1 1 NPS NPS 9761848 9761848 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 4mba NO 1 1 NPS NPS 2926816 2926816 Myoglobin is well known to be monomeric -- Annotation transfered from 2fal 4mbn NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 4mbp PROBNOT 1 1 NPS NPS 9309217 9309217 EcoCyc says monomer -- Annotation transfered from 1nl5 4mdh NO 2 2 C2 C2 2775751 2775751 SP says dimer 4nll PROBNOT 1 1 NPS NPS 9063874 9063874 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 2fdx 4nos_1 PROBNOT 2 2 C2 C2 10074942 10409685 BU changed since last release and is now corrected - - automaticaly inferred from 1nsi 4nos_2 PROBNOT 2 2 C2 C2 10074942 10409685 BU changed since last release and is now corrected - - automaticaly inferred from 1nsi 4nse NO 2 2 C2 C2 9875848 9875848 Clear dimer -- Annotation transfered from 1fol 4nul PROBNOT 1 1 NPS NPS 9063874 9063874 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 2fdx 4ovo NA 2 2 NS NS 1870129 1870129 4p2p PROBNOT 2 2 C2 C2 1930837 1930837 Papers of identical structures speak about the dimer as something relevant but it is interesting to note that two modes of dimerization exist among these proteins. I have not seen this discussed -- Annotation transfered from 1fx9 4pad PROBNOT 1 1 NPS NPS 952885 952885 Papain is a 23,400-dalton single polypeptide -- Annotation transfered from 9pap 4pah YES 1 2 NPS C2 9843368 9843368 They speak of the: dimeric catalytic domain (residues 117-424) - Even though the tetramerization helix is missing, it should still be a dimer. -- Annotation transfered from 1dmw 4pal PROBNOT 1 1 NPS NPS 1880797 1880797 -- Annotation transfered from 1pal 4paz NO 1 1 NPS NPS 9341204 9341204 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 -- Annotation transfered from 8paz 4pbg_1 PROBNOT 1 1 NPS NPS 9223646 9223646 Paper says nothing about a dimer - PISA says monomer - automatic transfer from 2pbg 4pbg_2 PROBNOT 1 1 NPS NPS 9223646 9223646 Paper says nothing about a dimer - PISA says monomer - automatic transfer from 2pbg 4pcy PROBNOT 1 1 NPS NPS 3560221 3560221 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) -- Annotation transfered from 2pcy 4pep PROBNOT 1 1 NPS NPS 2115087 2115087 Pepsin genaraly described as a monomer. 4pfk NO 4 4 D2 D2 6115424 6115424 12015149: The eubacterial ATP-dependent PFKs, of which the E. coli enzyme is the best-studied example, are allosterically regulated homotetramers -- Annotation transfered from 6pfk 4pgm NO 4 4 D2 D2 9512715 0 11038361 and SP say tetramer 4pgt NO 2 2 C2 C2 10441116 10441116 -- Annotation transfered from 9gss 4phv NO 2 2 C2 C2 -1 0 -- Annotation transfered from 1ajx 4pnp NO 3 3 C3 C3 0 0 Paper says trimer -- Annotation transfered from 1v48 4prg PROBYES 4 2 C2 C2 10339548 15258145 BU changed since last release and is now incorrect - PISA says homodimer and identicals are homodimers - automaticaly inferred from 1wm0 4pro_1 PROBYES 2 1 C2 NPS 9808037 2611204 BU changed since last release and is now incorrect - 9846867 says monomer - automaticaly inferred from 1p05 4pti NO 1 1 NPS NPS -1 0 10731422 says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium - pH induced oligomerization -- Annotation transfered from 9pti 4q21 NO 1 1 NPS NPS 2406906 2406906 Ras proteins are monomeric G proteins -- Annotation transfered from 1ctq 4rat NO 1 1 NPS NPS 1547232 1547232 -- Annotation transfered from 6rsa 4rla NO 3 3 C3 C3 9265637 9265637 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference -- Annotation transfered from 1hqx 4rsd NO 1 1 NPS NPS 9636030 9636030 -- Annotation transfered from 6rsa 4rsk NO 1 1 NPS NPS 9860854 9860854 -- Annotation transfered from 3rsk 4rxn PROBNOT 1 1 NPS NPS 7411618 7411618 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes 4sdh NO 2 2 C2 C2 8289287 8289287 Paper and SP say dimer -- Annotation transfered from 7hbi 4tgl PROBNOT 1 1 NPS NPS 1737010 2046751 BU changed since last release and is now corrected - Bad structure (only CA) - automaticaly inferred from 5tgl 4tim PROBNOT 2 2 C2 C2 1895291 1895291 SP says dimer -- Annotation transfered from 6tim 4tli PROBNOT 1 1 NPS NPS 10651278 10651278 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 4tln PROBNOT 1 1 NPS NPS 7317361 7317361 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 4tmk YES 1 2 NPS C2 9826650 9826650 Homodimer 4tmn PROBNOT 2 2 C2 C2 3442675 3442675 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 8tln 4tms NO 2 2 C2 C2 2128651 2128651 SP says homodimer 4tmy_1 NO 1 1 NPS NPS 9521117 9521117 Paper says monomer - very interesting paper btw - automatic transfer from 1tmy 4tmy_2 NO 1 1 NPS NPS 9521117 9521117 Paper says monomer - very interesting paper btw - automatic transfer from 1tmy 4tnc PROBNOT 1 1 NPS NPS 3338985 3338985 -- Annotation transfered from 1ncx 4tsv NO 3 3 C3 C3 9442056 9442056 SP and paper say trimer 4ubp YES 3 9 NPS C3 10766443 10766443 Interface geometry conserved with 1e2f (64% id avg) 4upj NO 2 2 C2 C2 7658450 7658450 -- Annotation transfered from 1hii 4vhb NO 2 2 C2 C2 10448042 10448042 Paper says dimer -- interesting example to show a benchmark of what is a good interface because the interface with 5.5 resids is almost identical to that with 11!! Why is that? -- Annotation transfered from 1vhb 4vub NO 2 2 C2 C2 9917404 9917404 Paper says dimer: CcdB forms a dimer in the crystal, consistent with solution studies. -- Annotation transfered from 3vub 4xia NO 4 4 D2 D2 2769749 2769749 -- Annotation transfered from 1xlg 4xim NO 4 4 D2 D2 1610791 1610791 -- Annotation transfered from 5xin 4xis NO 4 4 D2 D2 2006134 2006134 4yas YES 1 2 NPS C2 10548044 10548044 PISA, SP, paper and I say homodimer -- Annotation transfered from 7yas 4znb_1 PROBNOT 1 1 NPS NPS 10210203 9730812 BU changed since last release and is now corrected - - automaticaly inferred from 1a7t 4znb_2 PROBNOT 1 1 NPS NPS 10210203 9730812 BU changed since last release and is now corrected - - automaticaly inferred from 1a7t 521p PROBYES 2 1 C2 NPS 2199064 2199064 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 5abp NO 1 1 NPS NPS 2818726 2818726 EcoCyc says monomer -- Annotation transfered from 1abe 5adh NO 2 2 C2 C2 3771574 3771574 -- Annotation transfered from 8adh 5at1 NO 12 12 D3 D3 2271528 2271528 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 5azu PROBYES 4 1 D2 NPS 1942029 1942029 This is hard to believe but it seems that azurin is a monomeric protein! 9094740 for example does not mention a tetramer nor a dimer. 11740504 says: in the crystal of wild type native azurin, the protein molecules pack as noncovalent dimers with their hydrophobic patches opposite each other (Fig. 1a,b)10, 11. Although there is no evidence of dimer formation in solution, this orientation has been suggested to be similar to the transient complex that is formed in solution during the electron self-exchange (e.s.e.) reaction 5bj3_1 NO 2 2 C2 C2 11432784 11432784 - automatic transfer from 1gck 5bj3_2 NO 2 2 C2 C2 11432784 11432784 - automatic transfer from 1gck 5bj4 NO 2 2 C2 C2 11432784 11432784 -- Annotation transfered from 1gck 5ca2 PROBNOT 1 1 NPS NPS 1909891 1909891 9000633 says monomeric -- Annotation transfered from 1uga 5cac PROBNOT 1 1 NPS NPS 3151019 3151019 9000633 says monomeric -- Annotation transfered from 1uga 5ccp PROBNOT 1 1 NPS NPS 8396972 8396972 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 5cel PROBNOT 1 1 NPS NPS 9466911 9466911 None of the papers speaks about a dimer - a dimer is found using PISA but visual inspection reveals a weak interface. -- Annotation transfered from 6cel 5cev_1 YES 6 6 D3 D3 10196128 10196128 Interface geometry conserved with 1gq6 (28%) -- bad interface -- interesting as the geometry of the trimers varies. - automatic transfer from 1cev 5cev_2 YES 6 6 D3 D3 10196128 10196128 Interface geometry conserved with 1gq6 (28%) -- bad interface -- interesting as the geometry of the trimers varies. - automatic transfer from 1cev 5cgt NO 1 1 NPS NPS 9738912 9738912 Paper says monomeric: Cyclodextrin glycosyltransferases (CGTases, EC 2.4.1.19) are of bacterial origin and are monomeric. They catalyze the -- Annotation transfered from 7cgt 5cha NA 4 1 C2 NPS 3980476 3980476 BU changed since last release and is now incorrect - They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 5chy NO 1 1 NPS NPS 9030562 9030562 CheY is a Mr 14,000 monomeric protein -- Annotation transfered from 1chn 5cna NO 4 4 D2 D2 15299352 0 SP says tetramer -- Annotation transfered from 1cjp 5cox_1 NO 2 2 C2 C2 8967954 10811226 - automatic transfer from 1cvu 5cox_2 NO 2 2 C2 C2 8967954 10811226 - automatic transfer from 1cvu 5cp4 PROBNOT 1 1 NPS NPS 9649301 9649301 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 5cpp PROBNOT 1 1 NPS NPS 2713354 2713354 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 5cpv PROBNOT 2 2 C2 C2 2777802 9385642 Sedimentation equilibrium analysis results show that the EF fragment exists in a monomer-dimer equilibrium when complexed with La3+ // This symmetry is conserved with 1b8c. Not very clear though 5cro_1 YES 2 2 C2 C2 9653036 10686105 Paper says dimer but the wrong one is found here (cf paper) - automatic transfer from 1d1l 5cro_2 YES 2 2 C2 C2 9653036 10686105 Paper says dimer but the wrong one is found here (cf paper) - automatic transfer from 1d1l 5crx YES 4 8 C4 C4 10377382 10377382 BU changed since last release and is now incorrect - -- Annotation transfered from 1kbu 5csc NO 2 2 C2 C2 2043641 2043641 Interface geometry conserved with 1a59 (27%) -- Annotation transfered from 6cts 5cts NO 2 2 C2 C2 2337600 2337600 Interface geometry conserved with 1a59 (27%) -- Annotation transfered from 6cts 5cyh PROBNOT 1 1 NPS NPS 8652512 8980234 Paper implies CypA is monomeric 5cyt PROBNOT 1 1 NPS NPS -1 0 5daa NO 2 2 C2 C2 9930994 9930994 Homodimer -- Annotation transfered from 2daa 5dfr PROBNOT 1 1 NPS NPS 1998681 1998681 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 5eaa NO 2 2 C2 C2 10708649 10708649 Interface geometry conserved with 2ay6 (45%) -- Annotation transfered from 1amr 5eas PROBNOT 1 1 NPS NPS 9295271 9295271 SP says monomer -- Annotation transfered from 5eau 5eat PROBNOT 1 1 NPS NPS 9295271 9295271 SP says monomer -- Annotation transfered from 5eau 5eau PROBNOT 1 1 NPS NPS 9295271 9295271 SP says monomer 5ebx NA 1 1 NPS NPS 2722828 2722828 All papers are useless impossible to find an answer %$@~# 5enl NO 2 2 C2 C2 2007121 8605183 Interface conserved with 1te6 (62% id) -- Annotation transfered from 1one 5er1 PROBNOT 1 1 NPS NPS -1 0 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 5er2 PROBNOT 1 1 NPS NPS 2676515 2676515 Most eukaryotic aspartic proteinases are monomeric -- Annotation transfered from 1e82 5est PROBNOT 1 1 NPS NPS 2611205 2611205 -- Annotation transfered from 1c1m 5fbp NO 4 4 D2 D2 1849642 1849642 -- Annotation transfered from 1eyi 5fd1 NO 1 1 NPS NPS 8245025 0 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 5fiv YES 1 2 NPS C2 10651036 10651036 -- Annotation transfered from 1b11 5fwg NO 2 2 C2 C2 8110735 8110735 -- Annotation transfered from 6gsv 5fx2 PROBNOT 1 1 NPS NPS 2002503 2002503 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 1f4p 5gal YES 2 1 C2 NPS 9760227 9760227 Paper says: The hGal-7 molecule crystallizes as a dimer, although in solution it is known to exist as a monomer unlike most other mammalian galectins, except Gal-10 (6). 5gch NA 4 1 C2 NPS 2261462 0 BU changed since last release and is now incorrect - They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 5gpb NO 2 2 C2 C2 2125493 2125493 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 5grt NO 2 2 C2 C2 9174360 9174360 Paper says dimer 5gss NO 2 2 C2 C2 9398518 9398518 -- Annotation transfered from 9gss 5gst NO 2 2 C2 C2 8241147 8241147 -- Annotation transfered from 6gsv 5hbi NO 2 2 C2 C2 9826511 9826511 Paper and SP say dimer -- Annotation transfered from 7hbi 5hpg PROBYES 2 1 C2 NPS 9521645 9521645 This is just a very small domain of much a larger protein so closed symmetry is unlikely - Paper says: Kringles have a propensity to naturally occur in tandem arrays and associate with one another to form more compact units. [...] Although a number of different arrangements utilizing local rather than crystallographic symmetry elements have been identified in crystal structures, such as 2-fold rotation axis and pseudo 21 and 31 screw axis-like symmetries, none correspond to the unique antiparallel C-terminal interface arrangement of K5HPg, in which 389 Å2 (13% of each kringle) of surface area is inaccessible to solvent. However, the most distinguishing characteristic of the K5HPg dimer, as compared to other kringles, is the large number of water molecules mediating the dimer interface. Whether this is physiologically relevant remains to be shown by structure determination of a tandem kringle array. 5hvp NO 2 2 C2 C2 2201682 2201682 -- Annotation transfered from 1ajx 5i1b PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 21bi 5jdw YES 2 2 NS C2 9915841 9915841 Paper says: The sedimentation analysis shows that AT and its mutants ATDelta M302 and ATDelta 11, as well as StrB1, form homodimers and that the mutations did not affect dimerization. -- Annotation transfered from 1jdx 5lip PROBNOT 1 1 NPS NPS 9660188 9660188 SP says monomer, PISA too 5lpr NO 1 1 NPS NPS 1931963 1931963 9846867 says monomer -- Annotation transfered from 1p05 5lve NO 2 2 C2 C2 11045631 11045631 Interface conserved down to <30% (1cd8)! -- Annotation transfered from 1lve 5lym_1 NO 1 1 NPS NPS 15299739 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 5lym_2 NO 1 1 NPS NPS 15299739 1185784 Lysozyme C is well established as being monomeric - automatic transfer from 8lyz 5lyt NO 1 1 NPS NPS -1 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 5lyz NO 1 1 NPS NPS 4856347 4856347 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 5lzm NO 1 1 NPS NPS 2062826 2062826 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 5mba NO 1 1 NPS NPS 1931125 1931125 Myoglobin is well known to be monomeric -- Annotation transfered from 2fal 5mbn NO 1 1 NPS NPS -1 0 Myoglobin is a monomeric protein (8663546) -- Annotation transfered from 1a6m 5mdh NO 2 2 C2 C2 10075524 10075524 SP says dimer -- Annotation transfered from 4mdh 5nll PROBNOT 1 1 NPS NPS 9063874 9063874 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 2fdx 5nse NO 2 2 C2 C2 0 0 Clear dimer -- Annotation transfered from 1fol 5nuc NO 1 1 NPS NPS 8762134 8762134 Paper says monomeric -- Annotation transfered from 1ena 5nul PROBNOT 1 1 NPS NPS 9063874 9063874 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 2fdx 5p21 PROBYES 2 1 C2 NPS 2196171 2196171 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 5p2p PROBNOT 2 2 C2 C2 2215698 2215698 SP says Monomer or homodimer, Acylation causes dimerization. Paper doent say if this dimer is relevant or not - PISA says dimer 5pad PROBNOT 1 1 NPS NPS 952885 952885 Papain is a 23,400-dalton single polypeptide -- Annotation transfered from 9pap 5pah YES 1 2 NPS C2 9843368 9843368 They speak of the: dimeric catalytic domain (residues 117-424) - Even though the tetramerization helix is missing, it should still be a dimer. -- Annotation transfered from 1dmw 5pal PROBNOT 1 1 NPS NPS 1542115 1542115 Similar structures are either monomers or weak dimers - Paper does not mention dimer - PISA says monomer 5paz NO 1 1 NPS NPS 9341204 9341204 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 -- Annotation transfered from 8paz 5pcy PROBNOT 1 1 NPS NPS 3560221 3560221 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) -- Annotation transfered from 2pcy 5pep PROBNOT 1 1 NPS NPS 2115088 2115088 Pepsin genaraly described as a monomer. -- Annotation transfered from 4pep 5pgm_1 NO 4 4 D2 D2 10064712 0 11038361 and SP say tetramer - automatic transfer from 4pgm 5pgm_2 NO 4 4 D2 D2 10064712 0 11038361 and SP say tetramer - automatic transfer from 4pgm 5prn NO 3 3 C3 C3 9684893 9684893 Interface geometry conserved with 1gfn (20%) -- Annotation transfered from 1prn 5pti NO 1 1 NPS NPS 6210373 6210373 10731422 says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium - pH induced oligomerization -- Annotation transfered from 9pti 5ptp PROBNOT 1 1 NPS NPS 1557349 1557349 -- Annotation transfered from 1az8 5rat NO 1 1 NPS NPS 1547232 1547232 -- Annotation transfered from 6rsa 5rla NO 3 3 C3 C3 9265637 9265637 Paper says trimeric - Also says that it is stable as a monomer (trimer -> monomer by single point mutation) -- interesting QS interference -- Annotation transfered from 1hqx 5rub NO 2 2 C2 C2 2107319 2107319 Paper says: In contrast to the hexadecameric plant enzyme, ribulose-P2 carboxylase from Rhodospirillum rubrum is a dimer of only large subunits. -- Annotation transfered from 1rus 5rxn PROBNOT 1 1 NPS NPS 0 0 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 4rxn 5tgl PROBYES 2 1 C2 NPS 2046751 2046751 Bad structure (only CA) 5tim PROBNOT 2 2 C2 C2 1880808 1880808 SP says dimer -- Annotation transfered from 6tim 5tli PROBNOT 1 1 NPS NPS 10651278 10651278 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 5tln PROBNOT 1 1 NPS NPS 7317361 7317361 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 5tmn PROBNOT 2 2 C2 C2 3442675 3442675 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 8tln 5tmp YES 1 2 NPS C2 9826650 9826650 Homodimer -- Annotation transfered from 4tmk 5tnc PROBNOT 1 1 NPS NPS 3210231 3210231 -- Annotation transfered from 1ncx 5tsw_1 NO 3 3 C3 C3 9442056 9442056 SP and paper say trimer - automatic transfer from 4tsv 5tsw_2 NO 3 3 C3 C3 9442056 9442056 SP and paper say trimer - automatic transfer from 4tsv 5ttr_1 NO 4 4 D2 D2 9733771 11106758 - automatic transfer from 1g1o 5ttr_2 NO 4 4 D2 D2 9733771 11106758 - automatic transfer from 1g1o 5ttr_3 NO 4 4 D2 D2 9733771 11106758 - automatic transfer from 1g1o 5ull PROBNOT 1 1 NPS NPS 9063874 9063874 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 2fdx 5upj NO 2 2 C2 C2 7783120 7783120 -- Annotation transfered from 1hii 5xia NO 4 4 D2 D2 2769749 2769749 -- Annotation transfered from 1xlg 5xim NO 4 4 D2 D2 1610791 1610791 -- Annotation transfered from 5xin 5xin NO 4 4 D2 D2 1610791 1610791 5yas YES 1 2 NPS C2 10548044 10548044 PISA, SP, paper and I say homodimer -- Annotation transfered from 7yas 621p PROBYES 2 1 C2 NPS 2199064 2199064 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 6abp NO 1 1 NPS NPS 2069949 2069949 EcoCyc says monomer -- Annotation transfered from 1abe 6adh NO 2 2 C2 C2 7024556 7024556 -- Annotation transfered from 8adh 6at1 NO 12 12 D3 D3 2271528 2271528 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 6atj PROBNOT 1 1 NPS NPS 10574977 10574977 SP says monomer -- Annotation transfered from 7atj 6ca2 PROBNOT 1 1 NPS NPS 1932029 1932029 9000633 says monomeric -- Annotation transfered from 1uga 6ccp PROBNOT 1 1 NPS NPS 8396973 8396973 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 6cel PROBNOT 1 1 NPS NPS 9466911 9466911 None of the papers speaks about a dimer - a dimer is found using PISA but visual inspection reveals a weak interface. 6cgt NO 1 1 NPS NPS 9738912 9738912 Paper says monomeric: Cyclodextrin glycosyltransferases (CGTases, EC 2.4.1.19) are of bacterial origin and are monomeric. They catalyze the -- Annotation transfered from 7cgt 6cha NA 4 1 C2 NPS 3584139 3584139 BU changed since last release and is now incorrect - They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 6chy_1 PROBNOT 1 1 NPS NPS 9030562 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 6chy_2 PROBNOT 1 1 NPS NPS 9030562 2999789 BU changed since last release and is now corrected - CheY is a Mr 14,000 monomeric protein - automaticaly inferred from 1fqw 6cox NO 2 2 C2 C2 8967954 8967954 -- Annotation transfered from 1cvu 6cp4 PROBNOT 1 1 NPS NPS 9649301 9649301 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 6cpp PROBNOT 1 1 NPS NPS 2001355 2001355 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 6cro NO 2 2 C2 C2 9653037 9653037 Right dimer 6csc NO 2 2 C2 C2 0 0 Interface geometry conserved with 1a59 (27%) -- Annotation transfered from 6cts 6cts NO 2 2 C2 C2 2337600 2337600 Interface geometry conserved with 1a59 (27%) 6dfr PROBNOT 1 1 NPS NPS 2185835 2185835 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 6ebx NA 2 2 C2 C2 1418823 1418823 All papers are useless impossible to find an answer %$@~# -- Annotation transfered from 1qkd 6enl NO 2 2 C2 C2 2007121 8605183 Interface conserved with 1te6 (62% id) -- Annotation transfered from 1one 6est PROBNOT 1 1 NPS NPS 2354062 2354062 -- Annotation transfered from 1c1m 6fd1 NO 1 1 NPS NPS 9600844 9600844 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 6fdr NO 1 1 NPS NPS 10387068 10387068 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 6fiv YES 1 2 NPS C2 10651036 10651036 -- Annotation transfered from 1b11 6gch NA 4 1 C2 NPS 2271520 2271520 BU changed since last release and is now incorrect - They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 6gpb NO 2 2 C2 C2 2106586 2106586 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 6gss NO 2 2 C2 C2 9398518 9398518 -- Annotation transfered from 9gss 6gst NO 2 2 C2 C2 8664265 8664265 -- Annotation transfered from 6gsv 6gsu NO 2 2 C2 C2 8664265 8664265 -- Annotation transfered from 6gsv 6gsv NO 2 2 C2 C2 8664265 8664265 6gsw NO 2 2 C2 C2 8664265 8664265 -- Annotation transfered from 6gsv 6gsx NO 2 2 C2 C2 8664265 8664265 -- Annotation transfered from 6gsv 6gsy NO 2 2 C2 C2 8664265 8664265 -- Annotation transfered from 6gsv 6hbi NO 2 2 C2 C2 9826511 9826511 Paper and SP say dimer -- Annotation transfered from 7hbi 6jdw YES 2 2 NS C2 9915841 9915841 Paper says: The sedimentation analysis shows that AT and its mutants ATDelta M302 and ATDelta 11, as well as StrB1, form homodimers and that the mutations did not affect dimerization. -- Annotation transfered from 1jdx 6ldh PROBNOT 4 4 D2 D2 3430615 3430615 Tight tetramer, PISA agrees. -- 8ldh is strange though: less contacts than the others (1ldm). Why is that? Check - possible error/bug -- Annotation transfered from 8ldh 6lpr NO 1 1 NPS NPS 1931963 1931963 9846867 says monomer -- Annotation transfered from 1p05 6lyt NO 1 1 NPS NPS -1 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 6lyz NO 1 1 NPS NPS 4856347 4856347 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 6lzm NO 1 1 NPS NPS 2062826 2062826 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 6nse NO 2 2 C2 C2 0 0 Clear dimer -- Annotation transfered from 1fol 6nul PROBNOT 1 1 NPS NPS 9063874 9063874 8772174 says: Flavodoxins are a group of small, monomeric flavoproteins -- Annotation transfered from 2fdx 6pad PROBNOT 1 1 NPS NPS 952885 952885 Papain is a 23,400-dalton single polypeptide -- Annotation transfered from 9pap 6pah YES 2 2 NS C2 9843368 9843368 6paz NO 1 1 NPS NPS 9341204 9341204 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 -- Annotation transfered from 8paz 6pcy PROBNOT 1 1 NPS NPS 3560221 3560221 plastocyanins are monomeric proteins. (the newly designed nonpolar lysine mutants elute at times similar to that of plastocyanin, a monomeric -sheet protein with a mass of 10.6 kDa PID=11880628) -- Annotation transfered from 2pcy 6pfk NO 4 4 D2 D2 2136935 2136935 12015149: The eubacterial ATP-dependent PFKs, of which the E. coli enzyme is the best-studied example, are allosterically regulated homotetramers 6prn NO 3 3 C3 C3 9684893 9684893 Interface geometry conserved with 1gfn (20%) -- Annotation transfered from 1prn 6pti NO 1 1 NPS NPS 2448484 2448484 10731422 says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium - pH induced oligomerization -- Annotation transfered from 9pti 6q21 PROBYES 4 1 C4 NPS 2406906 2406906 6rat NO 1 1 NPS NPS 1547232 1547232 -- Annotation transfered from 6rsa 6rxn PROBNOT 1 1 NPS NPS 2091025 2091025 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes 6taa PROBNOT 1 1 NPS NPS 1930835 1930835 SP says monomer 6tim PROBNOT 2 2 C2 C2 2062828 2062828 SP says dimer 6tli PROBNOT 1 1 NPS NPS 10651278 10651278 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 6tmn PROBNOT 2 2 C2 C2 3810156 3810156 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 8tln 6upj NO 2 2 C2 C2 7783120 7783120 -- Annotation transfered from 1hii 6xia NO 4 4 D2 D2 2085424 2085424 -- Annotation transfered from 4xis 6xim NO 4 4 D2 D2 1610791 1610791 -- Annotation transfered from 5xin 6yas YES 1 2 NPS C2 10548044 10548044 PISA, SP, paper and I say homodimer -- Annotation transfered from 7yas 721p PROBYES 2 1 C2 NPS 2199064 2199064 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 7aat NO 2 2 C2 C2 1593633 1593633 Interface geometry conserved with 2ay6 (38%) -- Annotation transfered from 1ivr 7abp NO 1 1 NPS NPS 2069949 2069949 EcoCyc says monomer -- Annotation transfered from 1abe 7adh YES 1 2 NPS C2 6343388 6343388 7at1 NO 12 12 D3 D3 2271529 2271529 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 7atj PROBNOT 1 1 NPS NPS 10574977 10574977 SP says monomer 7ca2 PROBNOT 1 1 NPS NPS 1932029 1932029 9000633 says monomeric -- Annotation transfered from 1uga 7cat YES 4 4 C2 D2 3856839 0 BU changed since last release and is now incorrect - The BioUnit in the PDB is just wrong. It doesn t make any physical sense - the subunits are separated by 100 Angstroms of empty space. 7ccp PROBNOT 1 1 NPS NPS 8396973 8396973 Peroxidases seem to be monomeric in general. This one forms a one-to-one complex with cytochome c so it should be (info from SP). -- Annotation transfered from 3ccp 7cel PROBNOT 1 1 NPS NPS 9466911 9466911 None of the papers speaks about a dimer - a dimer is found using PISA but visual inspection reveals a weak interface. -- Annotation transfered from 6cel 7cgt NO 1 1 NPS NPS 9738912 9738912 Paper says monomeric: Cyclodextrin glycosyltransferases (CGTases, EC 2.4.1.19) are of bacterial origin and are monomeric. They catalyze the 7cpp PROBNOT 1 1 NPS NPS 2713354 2713354 BioCyc says monomer - PISA too - tens have been crystallised as monomers -- Annotation transfered from 8cpp 7dfr PROBNOT 1 1 NPS NPS 2185835 2185835 ECOcyc says monomer - PISA says dimer -- Annotation transfered from 1drh 7enl NO 2 2 C2 C2 2007120 8605183 Interface conserved with 1te6 (62% id) -- Annotation transfered from 1one 7est PROBNOT 1 1 NPS NPS 2354062 2354062 -- Annotation transfered from 1c1m 7fd1 NO 1 1 NPS NPS 10387068 10387068 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 7fdr NO 1 1 NPS NPS 10387068 10387068 paper 9915836 says: Although in the crystalline state AvFdI is clearly a monomer (2-5), previous studies have suggested that the homologous seven-iron ferredoxins from S. griseus (40), P. ovalis (41), and Sulfolobus acidocaldarius (42) might form dimers under certain conditions in solution. In general, the more physiological conditions of low salt (40) and, as shown in Fig. 2, lower pH tend to favor the formation of dimers. In addition, FdI does have a regulatory function, and it has been proposed that this function might involve dimer formation (43). None of these data are definitive, but they do leave open the possibility that either the metabolic or regulatory functions of FdI may involve dimer formation. -- Annotation transfered from 1frm 7gch NA 4 1 C2 NPS 2271520 2271520 BU changed since last release and is now incorrect - They explain in the paper (3980476) that chymotrypsin can form an asymmetric dimer, but can also be found as a monomer in particular conditions. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 4cha 7gpb NO 4 4 D2 D2 1900534 1900534 Paper says: Phosphorylase reconstituted with PLPP is not active, but the modified enzyme exhibits properties the of R-state conformation as detected by high affinity for AMP and aggregation of dimers to tetramers (Withers et al., 1982). -- Annotation transfered from 1abb 7gss NO 2 2 C2 C2 9398518 9398518 -- Annotation transfered from 9gss 7hbi NO 2 2 C2 C2 9826511 9826511 Paper and SP say dimer 7hvp NO 2 2 C2 C2 2247451 2247451 -- Annotation transfered from 1ajx 7jdw YES 2 2 NS C2 9915841 9915841 Paper says: The sedimentation analysis shows that AT and its mutants ATDelta M302 and ATDelta 11, as well as StrB1, form homodimers and that the mutations did not affect dimerization. -- Annotation transfered from 1jdx 7lpr NO 1 1 NPS NPS 1931963 1931963 9846867 says monomer -- Annotation transfered from 1p05 7lyz NO 1 1 NPS NPS -1 0 Lysozyme C is well established as being monomeric -- Annotation transfered from 8lyz 7lzm NO 1 1 NPS NPS 2062826 2062826 Phage T4 lysosyme is monomeric -- Annotation transfered from 1l10 7nse NO 2 2 C2 C2 0 0 Clear dimer -- Annotation transfered from 1fol 7paz NO 1 1 NPS NPS 9341204 9341204 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 -- Annotation transfered from 8paz 7pck YES 4 1 NS NPS 10048321 10074491 BU changed since last release and is now incorrect - Cathepsin K was synthesized as a prepropeptide of 37 kDa, and the mature enzyme was a monomeric protein with an apparent molecular mass of about 29 kDa 7pcy NA 4 4 C4 C4 2308169 2308169 Plastocyanin is normally a monomeric protein but this interface seems quite strong. difficult case. PISA says monomeric but I would like to see the paper before making a judgment. 7prn NO 3 3 C3 C3 9684893 9684893 Interface geometry conserved with 1gfn (20%) -- Annotation transfered from 1prn 7pti NO 1 1 NPS NPS 1699222 1699222 10731422 says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium - pH induced oligomerization -- Annotation transfered from 9pti 7rat NO 1 1 NPS NPS 1547232 1547232 -- Annotation transfered from 6rsa 7rsa NO 1 1 NPS NPS 3401445 3401445 -- Annotation transfered from 6rsa 7rxn PROBNOT 1 1 NPS NPS 1992166 1992166 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes 7taa PROBNOT 1 1 NPS NPS 9283074 9283074 SP says monomer -- Annotation transfered from 6taa 7tim NO 2 2 C2 C2 2043623 2043623 Interface geometry conserved with 1m6j (43%) 7tli PROBNOT 1 1 NPS NPS 10651278 10651278 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 7tln PROBNOT 1 1 NPS NPS 6830761 6830761 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 7upj NO 2 2 C2 C2 9089336 9089336 -- Annotation transfered from 1ajx 7xim NO 4 4 D2 D2 1610791 1610791 -- Annotation transfered from 5xin 7yas YES 1 2 NPS C2 10548044 10548044 PISA, SP, paper and I say homodimer 821p PROBYES 2 1 C2 NPS 8357792 8357792 Ras proteins are monomeric G proteins (not dimeric) -- Annotation transfered from 121p 830c_1 PROBNOT 1 1 NPS NPS 10074939 10074939 BU changed since last release and is now corrected - - automaticaly inferred from 456c 830c_2 PROBNOT 1 1 NPS NPS 10074939 10074939 BU changed since last release and is now corrected - - automaticaly inferred from 456c 8aat NO 2 2 C2 C2 1593633 1593633 Interface geometry conserved with 2ay6 (38%) -- Annotation transfered from 1ivr 8abp NO 1 1 NPS NPS 2069949 2069949 EcoCyc says monomer -- Annotation transfered from 1abe 8adh NO 2 2 C2 C2 3771574 3771574 8at1 NO 12 12 D3 D3 2271529 2271529 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 8ca2 PROBNOT 1 1 NPS NPS 1932029 1932029 9000633 says monomeric -- Annotation transfered from 1uga 8cat NO 4 4 D2 D2 3856839 3856839 Interface geometry conserved with 1mqf (50% id) -- Annotation transfered from 4blc 8cgt NO 1 1 NPS NPS 9738912 9738912 Paper says monomeric: Cyclodextrin glycosyltransferases (CGTases, EC 2.4.1.19) are of bacterial origin and are monomeric. They catalyze the -- Annotation transfered from 7cgt 8cho PROBNOT 2 2 C2 C2 9622484 9369474 8cpp PROBNOT 1 1 NPS NPS 2001355 2001355 BioCyc says monomer - PISA too - tens have been crystallised as monomers 8dfr NA 1 2 NPS C2 0 0 Not sure about the oligomeric state. PISA says dimer, but in Human it is clearly a monomer. That could be interessting -- Annotation transfered from 1dr7 8est PROBNOT 1 1 NPS NPS 2337582 2337582 -- Annotation transfered from 1c1m 8gch NA 2 1 NPS NPS 2036388 2036388 BU changed since last release and is now incorrect - They explain in the paper (3980476) that chymotrypsin can form an asymetric dimer, but can also be found as a monomer in particular conditions. Here PISA says monomer. Note that this protein has been the subject of many discussions in respect to its oligomeric state. For safety, I ll say that alpha (believed to be dimeric in some references) and gamma chymotrypsin (believed to be a monomer) are not well defined (NA). -- Annotation transfered from 1ex3 8gpb NO 2 2 C2 C2 1900534 1900534 phosphorylase a can exist in two states of aggregation: a catalytically more active dimer and a less active tetramer (Wang and Graves, 1964) -- Annotation transfered from 3gpb 8gss_1 NO 2 2 C2 C2 9398518 9398518 - automatic transfer from 9gss 8gss_2 NO 2 2 C2 C2 9398518 9398518 - automatic transfer from 9gss 8hvp NO 2 2 C2 C2 1993177 1993177 -- Annotation transfered from 1ajx 8i1b PROBNOT 1 1 NPS NPS 0 0 SP says monomer -- Annotation transfered from 2mib 8jdw YES 2 2 NS C2 9915841 9915841 Paper says: The sedimentation analysis shows that AT and its mutants ATDelta M302 and ATDelta 11, as well as StrB1, form homodimers and that the mutations did not affect dimerization. -- Annotation transfered from 1jdx 8ldh PROBNOT 4 4 D2 D2 3430615 3430615 Tight tetramer, PISA agrees. -- 8ldh is strange though: less contacts than the others (1ldm). Why is that? Check - possible error/bug 8lpr NO 1 1 NPS NPS 1931963 1931963 9846867 says monomer -- Annotation transfered from 1p05 8lyz NO 1 1 NPS NPS 1185784 1185784 Lysozyme C is well established as being monomeric 8nse NO 2 2 C2 C2 11695891 11695891 Clear dimer -- Annotation transfered from 1fol 8ohm NA 2 2 C2 C2 9614113 9614113 Although Rep DNA helicase, for example, is a stable monomer in solution in the absence of DNA, a dimeric form of Rep is induced in the presence of DNA which is known as the functional form. However, PISA doesnt believe this particular dimer, the true one might be 1hei. 8paz NO 1 1 NPS NPS 9341204 9341204 pseudoazurin is predominantly monomeric in solution Williams et al., 1995 8prk PROBNOT 2 2 C2 C2 9878371 9878371 SP says dimer -- Annotation transfered from 1wgi 8prn NO 3 3 C3 C3 9684893 9684893 Interface geometry conserved with 1gfn (20%) -- Annotation transfered from 1prn 8pti NO 1 1 NPS NPS 1714504 1714504 10731422 says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium - pH induced oligomerization -- Annotation transfered from 9pti 8rat NO 1 1 NPS NPS 1547232 1547232 -- Annotation transfered from 6rsa 8rsa YES 2 1 C2 NPS 2340284 2340284 No domain swapping - Known as a monomer, SP and PISA say monomer 8rxn PROBNOT 1 1 NPS NPS 1616692 1616692 11454214 says: rubredoxins are small, monomeric and mononuclear iron proteins found in many prokaryotes -- Annotation transfered from 7rxn 8tim NO 2 2 C2 C2 0 0 Interface geometry conserved with 1m6j (52%) - paper says dimer -- Annotation transfered from 1sq7 8tli PROBNOT 1 1 NPS NPS 10651278 10651278 thermolysin fragment corresponds to a mixture of monomers and dimers -- Annotation transfered from 1os0 8tln PROBNOT 2 2 C2 C2 1445869 8639498 thermolysin fragment corresponds to a mixture of monomers and dimers 8xia NO 4 4 D2 D2 2734296 2734296 -- Annotation transfered from 4xis 8xim NO 4 4 D2 D2 1610791 1610791 -- Annotation transfered from 5xin 966c PROBNOT 1 1 NPS NPS 10074939 10074939 No clear evidence after a quick search but PISA agrees ... -- Annotation transfered from 1hfc 9aat NO 2 2 C2 C2 1593633 1593633 Interface geometry conserved with 2ay6 (38%) -- Annotation transfered from 1ivr 9abp NO 1 1 NPS NPS 2204627 2204627 EcoCyc says monomer -- Annotation transfered from 1abe 9atc NO 12 12 D3 D3 9829701 9829701 SP says: Heterododecamer (2C3:3R2) of six catalytic pyrB chains organized as two trimers (C3), and six regulatory pyrI chains organized as three dimers (R2) -- Annotation transfered from 1raa 9ca2 PROBNOT 1 1 NPS NPS 1932029 1932029 9000633 says monomeric -- Annotation transfered from 1uga 9cgt NO 1 1 NPS NPS 9738912 9738912 Paper says monomeric: Cyclodextrin glycosyltransferases (CGTases, EC 2.4.1.19) are of bacterial origin and are monomeric. They catalyze the -- Annotation transfered from 7cgt 9est PROBNOT 1 1 NPS NPS 1998677 1998677 -- Annotation transfered from 1c1m 9gpb NO 4 4 D2 D2 2770867 2770867 Paper says: Phosphorylase reconstituted with PLPP is not active, but the modified enzyme exhibits properties the of R-state conformation as detected by high affinity for AMP and aggregation of dimers to tetramers (Withers et al., 1982). -- Annotation transfered from 1abb 9gss NO 2 2 C2 C2 9398518 9398518 9hvp NO 2 2 C2 C2 2200122 2200122 -- Annotation transfered from 1ajx 9ilb PROBNOT 1 1 NPS NPS 9874779 9874779 SP says monomer -- Annotation transfered from 21bi 9jdw YES 2 2 NS C2 9915841 9915841 Paper says: The sedimentation analysis shows that AT and its mutants ATDelta M302 and ATDelta 11, as well as StrB1, form homodimers and that the mutations did not affect dimerization. -- Annotation transfered from 1jdx 9ldb PROBNOT 4 4 D2 D2 1678537 1678537 -- Annotation transfered from 9ldt 9ldt PROBNOT 4 4 D2 D2 1678537 1678537 9lpr NO 1 1 NPS NPS 1931963 1931963 9846867 says monomer -- Annotation transfered from 1p05 9nse NO 2 2 C2 C2 11051558 11051558 Clear dimer -- Annotation transfered from 1fol 9pai PROBNOT 1 1 NPS NPS 7552714 7552714 Paper says nothing - Family mostly monomeric - PISA says monomer -- Annotation transfered from 1dvn 9pap PROBNOT 1 1 NPS NPS 6502713 3304137 Papain is a 23,400-dalton single polypeptide 9pti NO 1 1 NPS NPS 0 0 10731422 says: co-existence of two different BPTI particles in solution: a monomer and a decamer, with no evidence of any other intermediates. Moreover, using both approaches, the fraction of decamers was found to increase with increasing salt concentration - monomer decamer equilibrium - pH induced oligomerization 9rat NO 1 1 NPS NPS 1547232 1547232 -- Annotation transfered from 6rsa 9rsa YES 2 1 C2 NPS 2340284 2340284 No domain swapping - Known as a monomer, SP and PISA say monomer 9rub NO 2 2 C2 C2 1905726 1905726 Paper says: In contrast to the hexadecameric plant enzyme, ribulose-P2 carboxylase from Rhodospirillum rubrum is a dimer of only large subunits. -- Annotation transfered from 1rus 9xia NO 4 4 D2 D2 2734296 2734296 -- Annotation transfered from 4xis 9xim NO 4 4 D2 D2 1610791 1610791 -- Annotation transfered from 5xin